Search of human proteins with 154759275

Search of human proteins with 154759275

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154759275 monocyte to macrophage differentiation-associated
2 isoform 2 [Homo sapiens]
         (246 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154759275 monocyte to macrophage differentiation-associated 2...   528   e-150
gi|154759277 monocyte to macrophage differentiation-associated 2...   514   e-146
gi|52630445 monocyte to macrophage differentiation-associated pr...   365   e-101
gi|118600969 C-type lectin domain family 17, member A [Homo sapi...    32   0.39 
gi|38261973 adiponectin receptor 2 [Homo sapiens]                      32   0.66 
gi|12965172 taste receptor, type 2, member 9 [Homo sapiens]            30   1.9  
gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]             29   4.3  
gi|12408663 T-lymphocyte maturation-associated protein isoform c...    29   4.3  
gi|29789379 sphingomyelin synthase 1 [Homo sapiens]                    28   5.6  
gi|23097338 neurexophilin 1 precursor [Homo sapiens]                   28   5.6  
gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]      28   5.6  
gi|52138515 neurexophilin 2 [Homo sapiens]                             28   7.3  
gi|210147409 sphingomyelin synthase 2 [Homo sapiens]                   28   7.3  
gi|210147407 sphingomyelin synthase 2 [Homo sapiens]                   28   7.3  
gi|22749271 sphingomyelin synthase 2 [Homo sapiens]                    28   7.3  
gi|195963433 syncytin precursor [Homo sapiens]                         28   9.5  
gi|48949851 syncytin precursor [Homo sapiens]                          28   9.5  
gi|30578410 source of immunodominant MHC-associated peptides [Ho...    28   9.5  

>gi|154759275 monocyte to macrophage differentiation-associated 2
           isoform 2 [Homo sapiens]
          Length = 246

 Score =  528 bits (1359), Expect = e-150
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MFAPRLLDFQKTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLS 60
           MFAPRLLDFQKTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLS
Sbjct: 1   MFAPRLLDFQKTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLS 60

Query: 61  DDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYA 120
           DDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYA
Sbjct: 61  DDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYA 120

Query: 121 PWLNLRELGPWASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVVMGFFPALVILSMP 180
           PWLNLRELGPWASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVVMGFFPALVILSMP
Sbjct: 121 PWLNLRELGPWASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVVMGFFPALVILSMP 180

Query: 181 NTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWHLFVAFGAGTHYYAIWRYLYLPSTL 240
           NTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWHLFVAFGAGTHYYAIWRYLYLPSTL
Sbjct: 181 NTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWHLFVAFGAGTHYYAIWRYLYLPSTL 240

Query: 241 QTKVSK 246
           QTKVSK
Sbjct: 241 QTKVSK 246


>gi|154759277 monocyte to macrophage differentiation-associated 2
           isoform 1 [Homo sapiens]
          Length = 270

 Score =  514 bits (1324), Expect = e-146
 Identities = 246/270 (91%), Positives = 246/270 (91%), Gaps = 24/270 (8%)

Query: 1   MFAPRLLDFQKTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLS 60
           MFAPRLLDFQKTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLS
Sbjct: 1   MFAPRLLDFQKTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLS 60

Query: 61  DDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYA 120
           DDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYA
Sbjct: 61  DDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYA 120

Query: 121 PWLNLRELGPWASHMRWLVWIMASVGTIYVFFFHE------------------------R 156
           PWLNLRELGPWASHMRWLVWIMASVGTIYVFFFHE                        R
Sbjct: 121 PWLNLRELGPWASHMRWLVWIMASVGTIYVFFFHERTGSCVQFLRGEACPKAGTACLPAR 180

Query: 157 YKLVELLCYVVMGFFPALVILSMPNTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWH 216
           YKLVELLCYVVMGFFPALVILSMPNTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWH
Sbjct: 181 YKLVELLCYVVMGFFPALVILSMPNTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWH 240

Query: 217 LFVAFGAGTHYYAIWRYLYLPSTLQTKVSK 246
           LFVAFGAGTHYYAIWRYLYLPSTLQTKVSK
Sbjct: 241 LFVAFGAGTHYYAIWRYLYLPSTLQTKVSK 270


>gi|52630445 monocyte to macrophage differentiation-associated
           precursor [Homo sapiens]
          Length = 238

 Score =  365 bits (937), Expect = e-101
 Identities = 165/229 (72%), Positives = 191/229 (83%)

Query: 11  KTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLSDDDWETISAW 70
           K ++ RFMNHR PA+ RY+PT YEHAANC THAF I+P+I+GS+ L+ LSDD WE I+AW
Sbjct: 4   KNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKITAW 63

Query: 71  IYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYAPWLNLRELGP 130
           IYG+GLC LF+VSTVFH +SWKKSHLR VEHC HM DRMVIYFFIAASYAPWLNLRELGP
Sbjct: 64  IYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRELGP 123

Query: 131 WASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVVMGFFPALVILSMPNTEGIWELVT 190
            ASHMRW +W+MA+ GTIYVF +HE+YK+VEL  Y+ MGF PALV+ SM NT+G+ EL  
Sbjct: 124 LASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQELAC 183

Query: 191 GGVFYCLGMVFFKSDGRIPFAHAIWHLFVAFGAGTHYYAIWRYLYLPST 239
           GG+ YCLG+VFFKSDG IPFAHAIWHLFVA  A  HYYAIW+YLY   T
Sbjct: 184 GGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPT 232


>gi|118600969 C-type lectin domain family 17, member A [Homo
           sapiens]
          Length = 289

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 14/33 (42%), Positives = 19/33 (57%)

Query: 115 IAASYAPWLNLRELGPWASHMRWLVWIMASVGT 147
           +AA+  PWLN R  GP     RW+V++   V T
Sbjct: 130 LAATPVPWLNQRSGGPGCCQKRWMVYLCLLVVT 162


>gi|38261973 adiponectin receptor 2 [Homo sapiens]
          Length = 386

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 41/189 (21%), Positives = 68/189 (35%), Gaps = 34/189 (17%)

Query: 71  IYGLGLCGLFVV---STVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYAPWLNLR- 126
           ++GL   G  +    S +FHT+     H   V       D   I   I  S+ PWL    
Sbjct: 183 VFGLFFLGAILCLSFSWLFHTVY---CHSEGVSRLFSKLDYSGIALLIMGSFVPWLYYSF 239

Query: 127 ELGPWASHMRWLVWIMASVGTIYV----FFFHERYKLVELLCYVVMGFFPALVILSMPNT 182
              P    +  +V  +  +  I V     F   +Y+ V    ++ +G    +  L    +
Sbjct: 240 YCNPQPCFIYLIVICVLGIAAIIVSQWDMFATPQYRGVRAGVFLGLGLSGIIPTLHYVIS 299

Query: 183 EGIWELVTGGVF---------YCLGMVFFKSDGRIP------------FAHAIWHLFVAF 221
           EG  +  T G           Y  G   + +  RIP             +H ++H+FV  
Sbjct: 300 EGFLKAATIGQIGWLMLMASLYITGAALYAA--RIPERFFPGKCDIWFHSHQLFHIFVVA 357

Query: 222 GAGTHYYAI 230
           GA  H++ +
Sbjct: 358 GAFVHFHGV 366


>gi|12965172 taste receptor, type 2, member 9 [Homo sapiens]
          Length = 312

 Score = 30.0 bits (66), Expect = 1.9
 Identities = 12/65 (18%), Positives = 31/65 (47%)

Query: 122 WLNLRELGPWASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVVMGFFPALVILSMPN 181
           W        W +    + +++      + FFF  + K+ +++  +++G F   +I+S+P 
Sbjct: 89  WTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVMLAILLGSFLISLIISVPK 148

Query: 182 TEGIW 186
            + +W
Sbjct: 149 NDDMW 153


>gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]
          Length = 363

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 22/91 (24%)

Query: 70  WIYGLGLC---GLFVVSTVFHTISWKKSHLRMVEHCLHMFDRM--VIYFFIAASYAPWLN 124
           W++G  +C   G F+   +F +I +          C+ + DR   VIY F++    PW  
Sbjct: 110 WLFGPVMCKVFGSFLTLNMFASIFFIT--------CMSV-DRYQSVIYPFLSQRRNPWQ- 159

Query: 125 LRELGPWASHMRWLVWIMASVGTIYVFFFHE 155
                  AS++  LVW MA + ++  F+F +
Sbjct: 160 -------ASYIVPLVWCMACLSSLPTFYFRD 183


>gi|12408663 T-lymphocyte maturation-associated protein isoform c
          [Homo sapiens]
          Length = 97

 Score = 28.9 bits (63), Expect = 4.3
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 32 EYEHAANCATHAFWIIPSILGSSNLYFLSDDDW-----ETISAWIYGLGLCGLFVVSTVF 86
          E++ A +C    F++  S+L +     + D        E I+A ++      L+VV  VF
Sbjct: 30 EFDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVF 89

Query: 87 HTISWKKS 94
            I WK S
Sbjct: 90 SLIRWKSS 97


>gi|29789379 sphingomyelin synthase 1 [Homo sapiens]
          Length = 413

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 12/49 (24%), Positives = 25/49 (51%), Gaps = 5/49 (10%)

Query: 122 WLNLRELGP---WASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVV 167
           +L ++E  P   W  H  W+ W+++ VG   +   H+ Y +  ++ Y +
Sbjct: 293 YLFIKEYSPRRLWWYH--WICWLLSVVGIFCILLAHDHYTVDVVVAYYI 339


>gi|23097338 neurexophilin 1 precursor [Homo sapiens]
          Length = 271

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 133 SHMRWLVWIMASVGTIYVFFFHERYKLVELLC 164
           SH+ WL      V  IY+ F+   YKLV+ +C
Sbjct: 225 SHVSWLCSKPFKVICIYISFYSTDYKLVQKVC 256


>gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]
          Length = 293

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 31/127 (24%), Positives = 49/127 (38%), Gaps = 14/127 (11%)

Query: 17  FMNHRVPAHKRYQ-----PTEYEHAANCA-----THAFWIIPSILGSSNL--YFLSDDDW 64
           F+   +P  K+Y+     P  +E+   C       H    +P I G+     YF    DW
Sbjct: 70  FLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDW 129

Query: 65  ETISAWIYGLGLC-GLFVVSTVFHTISWKKSHLRMVEHCLH-MFDRMVIYFFIAASYAPW 122
           E +  W + L  C G  V+   +H    +  H + +   +H +       F + A YA  
Sbjct: 130 ERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHP 189

Query: 123 LNLRELG 129
           L    LG
Sbjct: 190 LETLILG 196


>gi|52138515 neurexophilin 2 [Homo sapiens]
          Length = 264

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 133 SHMRWLVWIMASVGTIYVFFFHERYKLVELLC 164
           SH+ WL      V  IY+ F+   YKLV+ +C
Sbjct: 218 SHVSWLCSKPFKVICIYIAFYSVDYKLVQKVC 249


>gi|210147409 sphingomyelin synthase 2 [Homo sapiens]
          Length = 365

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 12/49 (24%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 122 WLNLRELGP---WASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVV 167
           +L ++E  P   W  H+  + W++++ G I +   HE Y +  ++ Y +
Sbjct: 237 YLFIKEYSPRHFWWYHL--ICWLLSAAGIICILVAHEHYTIDVIIAYYI 283


>gi|210147407 sphingomyelin synthase 2 [Homo sapiens]
          Length = 365

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 12/49 (24%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 122 WLNLRELGP---WASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVV 167
           +L ++E  P   W  H+  + W++++ G I +   HE Y +  ++ Y +
Sbjct: 237 YLFIKEYSPRHFWWYHL--ICWLLSAAGIICILVAHEHYTIDVIIAYYI 283


>gi|22749271 sphingomyelin synthase 2 [Homo sapiens]
          Length = 365

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 12/49 (24%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 122 WLNLRELGP---WASHMRWLVWIMASVGTIYVFFFHERYKLVELLCYVV 167
           +L ++E  P   W  H+  + W++++ G I +   HE Y +  ++ Y +
Sbjct: 237 YLFIKEYSPRHFWWYHL--ICWLLSAAGIICILVAHEHYTIDVIIAYYI 283


>gi|195963433 syncytin precursor [Homo sapiens]
          Length = 538

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 9/24 (37%), Positives = 14/24 (58%)

Query: 125 LRELGPWASHMRWLVWIMASVGTI 148
           LR  GPW    +W+ WI+  +G +
Sbjct: 432 LRNTGPWGLLSQWMPWILPFLGPL 455


>gi|48949851 syncytin precursor [Homo sapiens]
          Length = 538

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 9/24 (37%), Positives = 14/24 (58%)

Query: 125 LRELGPWASHMRWLVWIMASVGTI 148
           LR  GPW    +W+ WI+  +G +
Sbjct: 432 LRNTGPWGLLSQWMPWILPFLGPL 455


>gi|30578410 source of immunodominant MHC-associated peptides [Homo
           sapiens]
          Length = 826

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 11/40 (27%), Positives = 21/40 (52%)

Query: 60  SDDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMV 99
           +D+    +S W YG  + G+   +T+    +W  SH+ +V
Sbjct: 595 TDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALV 634


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.142    0.497 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,612,904
Number of Sequences: 37866
Number of extensions: 394735
Number of successful extensions: 890
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 879
Number of HSP's gapped (non-prelim): 18
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.