Search of human proteins with 154759257

Search of human proteins with 154759257

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154759257 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Homo
sapiens]
         (666 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154759257 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Homo sap...  1312   0.0  
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   176   6e-44
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   161   2e-39
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   160   5e-39
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   145   2e-34
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi...   141   2e-33
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   139   6e-33
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   139   6e-33
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   138   2e-32
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   133   5e-31
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi...   132   1e-30
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ...   129   1e-29
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   127   4e-29
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   126   7e-29
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            123   5e-28
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            123   5e-28
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      122   8e-28
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]   122   1e-27
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   121   2e-27
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   121   2e-27
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   121   2e-27
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  120   3e-27
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   117   3e-26
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   117   3e-26
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         115   1e-25
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          115   1e-25
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   113   6e-25
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   110   4e-24
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   105   1e-22
gi|8922976 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Homo sapiens]   103   7e-22

>gi|154759257 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Homo
           sapiens]
          Length = 666

 Score = 1312 bits (3395), Expect = 0.0
 Identities = 666/666 (100%), Positives = 666/666 (100%)

Query: 1   MALFYVARYPGPDAAAAAGPEGAEAGAHGRARALLERLQSRARERQQQREPAQTEAAAST 60
           MALFYVARYPGPDAAAAAGPEGAEAGAHGRARALLERLQSRARERQQQREPAQTEAAAST
Sbjct: 1   MALFYVARYPGPDAAAAAGPEGAEAGAHGRARALLERLQSRARERQQQREPAQTEAAAST 60

Query: 61  EPATRRRRRPRRRRRVNDAEPGSPEAPQGKRRKADGEDAGAESNEEAPGEPSAGSSEEAP 120
           EPATRRRRRPRRRRRVNDAEPGSPEAPQGKRRKADGEDAGAESNEEAPGEPSAGSSEEAP
Sbjct: 61  EPATRRRRRPRRRRRVNDAEPGSPEAPQGKRRKADGEDAGAESNEEAPGEPSAGSSEEAP 120

Query: 121 GEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKVQPFLPR 180
           GEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKVQPFLPR
Sbjct: 121 GEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKVQPFLPR 180

Query: 181 WLAEPNCVRRNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGF 240
           WLAEPNCVRRNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGF
Sbjct: 181 WLAEPNCVRRNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGF 240

Query: 241 LVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKV 300
           LVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKV
Sbjct: 241 LVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKV 300

Query: 301 FNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGF 360
           FNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGF
Sbjct: 301 FNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGF 360

Query: 361 SLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCC 420
           SLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCC
Sbjct: 361 SLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCC 420

Query: 421 PQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLT 480
           PQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLT
Sbjct: 421 PQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLT 480

Query: 481 HHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYG 540
           HHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYG
Sbjct: 481 HHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYG 540

Query: 541 PGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAG 600
           PGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAG
Sbjct: 541 PGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAG 600

Query: 601 KTGQAFTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEE 660
           KTGQAFTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEE
Sbjct: 601 KTGQAFTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEE 660

Query: 661 RKQRAA 666
           RKQRAA
Sbjct: 661 RKQRAA 666


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  176 bits (446), Expect = 6e-44
 Identities = 130/469 (27%), Positives = 213/469 (45%), Gaps = 81/469 (17%)

Query: 209 LQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVI 268
           L K + A G     P+Q A IP               G    D+C  A TG+GKT AF +
Sbjct: 229 LLKAITAMGFKQPTPIQKACIPV--------------GLLGKDICACAATGTGKTAAFAL 274

Query: 269 PVVQALL--SRVVCHIRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQE 326
           PV++ L+   R     R LV++PT+EL  QV  V         +   L  G   +  ++ 
Sbjct: 275 PVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEA 334

Query: 327 SLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLP 386
           +L        R   DI++ATPGRL+DH+   P F L  +  LI+DEADRM+D   +  + 
Sbjct: 335 AL--------RAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMK 386

Query: 387 RVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGL 446
            ++                                    Q +LFSAT+T   + L  + L
Sbjct: 387 EIIRMCSHHR-----------------------------QTMLFSATMTDEVKDLASVSL 417

Query: 447 HQP-RLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYV---PCSLSSKPLVVLHLVLEM 502
             P R+F            + + D   +     L   ++   P     +  +V  L+   
Sbjct: 418 KNPVRIF-----------VNSNTDVAPF-----LRQEFIRIRPNREGDREAIVAALLTRT 461

Query: 503 GFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLIST 562
               V+ FT +++ +HR+ +L+   G + V E        QR   L++F+  +I +L++T
Sbjct: 462 FTDHVMLFTQTKKQAHRMHILLGLMG-LQVGELHGNLSQTQRLEALRRFKDEQIDILVAT 520

Query: 563 DATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERRFLRMLT 622
           D  ARG+D++GV+ V+N+  P  ++ YVHRVGRTARAG+ G++ +L+ +  ER+ L+ + 
Sbjct: 521 DVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGE-DERKMLKEIV 579

Query: 623 EAGAPELQRHELSSKLLQPLVPRYEE------ALSQLEESVKEERKQRA 665
           +A    ++   L   ++     + E+      A+ QLE   KE ++  A
Sbjct: 580 KAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEA 628


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  161 bits (407), Expect = 2e-39
 Identities = 114/412 (27%), Positives = 202/412 (49%), Gaps = 66/412 (16%)

Query: 251 DLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKVFNIYTDATPL 310
           D+   A TGSGKT AF +P++ ALL      + ALV+ PT+ELA Q+S+ F     +  +
Sbjct: 63  DIIGLAETGSGKTGAFALPILNALLETPQ-RLFALVLTPTRELAFQISEQFEALGSSIGV 121

Query: 311 RVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLII 370
           + +++ G      +  +L +K          I++ATPGRL+DH++ T GF+L+ L++L++
Sbjct: 122 QSAVIVGGIDSMSQSLALAKKP--------HIIIATPGRLIDHLENTKGFNLRALKYLVM 173

Query: 371 DEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLF 430
           DEADR+++   ++ + +++        P D                         +  LF
Sbjct: 174 DEADRILNMDFETEVDKILKVI-----PRDR------------------------KTFLF 204

Query: 431 SATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSS 490
           SAT+T+  +KLQ+  L  P   +                S KY     L  +Y+      
Sbjct: 205 SATMTKKVQKLQRAALKNPVKCAV---------------SSKYQTVEKLQQYYIFIPSKF 249

Query: 491 KPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQ 550
           K   +++++ E+  +  + F ++  N+ R  LL++  G   +     +    +R   L +
Sbjct: 250 KDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIP-LHGQMSQSKRLGSLNK 308

Query: 551 FEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLL 610
           F+     +L++TD  +RG+D+  V++VVN+D P + + Y+HRVGRTARAG++G+A T + 
Sbjct: 309 FKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT 368

Query: 611 KVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEERK 662
           +     F R+           H +  KL  P  P  ++ +  L E V E ++
Sbjct: 369 QYDVELFQRI----------EHLIGKKL--PGFPTQDDEVMMLTERVAEAQR 408


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  160 bits (404), Expect = 5e-39
 Identities = 138/466 (29%), Positives = 213/466 (45%), Gaps = 80/466 (17%)

Query: 209 LQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVI 268
           L +Q R  G+    PVQ   IPA+LE   C                 A TGSGKT AFV+
Sbjct: 13  LVEQCRQLGLKQPTPVQLGCIPAILEGRDC--------------LGCAKTGSGKTAAFVL 58

Query: 269 PVVQALLSRVVCHIRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESL 328
           P++Q L S     I  LV+ PT+ELA Q+++ F +      L+  ++ G   +  +   L
Sbjct: 59  PILQKL-SEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALEL 117

Query: 329 VQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRV 388
            +K          +V+ATPGRL DH+  +  FS++++RFL++DEADR+++          
Sbjct: 118 SRKP--------HVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQ--------- 160

Query: 389 VAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLHQ 448
               F  +  A   A+  RRQ                  LLFSATLT    +LQ L  +Q
Sbjct: 161 GCTDFTVDLEAILAAVPARRQT-----------------LLFSATLTDTLRELQGLATNQ 203

Query: 449 PRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFSR-- 506
           P  +        +E  D                 Y+      K   ++HL+         
Sbjct: 204 PFFWEAQAPVSTVEQLD---------------QRYLLVPEKVKDAYLVHLIQRFQDEHED 248

Query: 507 --VLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLISTDA 564
             ++ FTN+ +    L ++++ F    VA   S     +R   L +F+    ++LI+TD 
Sbjct: 249 WSIIIFTNTCKTCQILCMMLRKFSFPTVA-LHSMMKQKERFAALAKFKSSIYRILIATDV 307

Query: 565 TARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTL-------LLKVQERRF 617
            +RG+D+  V++V+N++ P   + Y+HRVGRTARAG+ GQA TL       L+   E + 
Sbjct: 308 ASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAIEEQI 367

Query: 618 LRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEERKQ 663
            + L E    E    E+   L Q  V R  E   +LE +  +E+K+
Sbjct: 368 KKKLEEFSVEEA---EVLQILTQVNVVR-RECEIKLEAAHFDEKKE 409


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  145 bits (365), Expect = 2e-34
 Identities = 116/419 (27%), Positives = 194/419 (46%), Gaps = 61/419 (14%)

Query: 251 DLCVSAPTGSGKTLAFVIPVVQALLS---RVVCHIRALVVLPTKELAQQVSKVFNIYTDA 307
           D+  +A TGSGKTLAF++PV++AL          +  L++ PT+ELA Q  +V       
Sbjct: 108 DVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKN 167

Query: 308 TPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRF 367
                 L+ G K L  E E +            +I+V TPGRL+ H+D+T  F    L+ 
Sbjct: 168 HDFSAGLIIGGKDLKHEAERINN---------INILVCTPGRLLQHMDETVSFHATDLQM 218

Query: 368 LIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQK 427
           L++DEADR++D      +  V+              L ++RQ                  
Sbjct: 219 LVLDEADRILDMGFADTMNAVIEN------------LPKKRQT----------------- 249

Query: 428 LLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCS 487
           LLFSAT T++ + L +L L  P                   +  KY+ P  L  +Y+ C 
Sbjct: 250 LLFSATQTKSVKDLARLSLKNPEYVWVH-------------EKAKYSTPATLEQNYIVCE 296

Query: 488 LSSKPLVVLHLVLEMGFSR--VLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRR 545
           L  K + VL+  L     +  ++ F++ +E  +   +  +   GV +     R    +R 
Sbjct: 297 LQQK-ISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRM 355

Query: 546 MILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQA 605
            +  +F + +  +L +TD  ARG+D   V  V+ +D P+   TY+HR GRTAR  + G+A
Sbjct: 356 EVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEA 415

Query: 606 FTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEERKQR 664
             +LL   E+  ++ L +   P ++  +++ + L  +  + E  L+Q ++   +ER QR
Sbjct: 416 LLILLP-SEKAMVQQLLQKKVP-VKEIKINPEKLIDVQKKLESILAQDQD--LKERAQR 470


>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
           sapiens]
          Length = 670

 Score =  141 bits (356), Expect = 2e-33
 Identities = 158/615 (25%), Positives = 252/615 (40%), Gaps = 134/615 (21%)

Query: 55  EAAASTEPATRRRRRPRRRRRVNDAEPGSPEAPQGKRRKADGEDAGAESNEEAPGEPSAG 114
           EAA  +  +  ++++ ++R+ VNDAEP + +A    + K++              E SA 
Sbjct: 97  EAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSE--------------EESAE 142

Query: 115 SSEEAPGEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKV 174
           +++E         ++E   E                       VP L LG  G  +    
Sbjct: 143 TTKETENNVEKPDNDEDESE-----------------------VPSLPLGLTGAFEDTSF 179

Query: 175 QPFLPRWLAEPNCVRRNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLE 234
                      N V  N                   K ++  G ++   +Q   I  LLE
Sbjct: 180 ASLC-------NLVNENTL-----------------KAIKEMGFTNMTEIQHKSIRPLLE 215

Query: 235 SAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRA---LVVLPTK 291
                   GR      DL  +A TGSGKTLAF+IP V+ ++            L++ PT+
Sbjct: 216 --------GR------DLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTR 261

Query: 292 ELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLV 351
           ELA Q   V             L+ G  + + E     QK  +G     +I+VATPGRL+
Sbjct: 262 ELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAE----AQKLGNGI----NIIVATPGRLL 313

Query: 352 DHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQ 411
           DH+  TPGF  + L+ L+IDEADR++D   +  L +++              LL  R+  
Sbjct: 314 DHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIK-------------LLPTRR-- 358

Query: 412 AVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSG 471
                         Q +LFSAT T+  E L ++ L +  L+             G  D  
Sbjct: 359 --------------QTMLFSATQTRKVEDLARISLKKEPLYV------------GVDDDK 392

Query: 472 KYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVD 531
             A   GL   YV C    + L++   + +    +++ F +S  +    + L+  +  + 
Sbjct: 393 ANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCMSVKYHYELLN-YIDLP 451

Query: 532 VAEFSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVH 591
           V     +    +R     QF       L+ TD  ARG+D+  V+ +V YD P   + Y+H
Sbjct: 452 VLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIH 511

Query: 592 RVGRTARAGKTGQAFTLL-LKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEAL 650
           RVGRTAR G  G+   LL L+ +E  FLR L ++  P L   + S   +  +  + E+ +
Sbjct: 512 RVGRTAR-GLNGRGHALLILRPEELGFLRYLKQSKVP-LSEFDFSWSKISDIQSQLEKLI 569

Query: 651 SQ---LEESVKEERK 662
            +   L +S +E  K
Sbjct: 570 EKNYFLHKSAQEAYK 584


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  139 bits (351), Expect = 6e-33
 Identities = 126/458 (27%), Positives = 203/458 (44%), Gaps = 83/458 (18%)

Query: 223 PVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHI 282
           P+Q   IP +L         GR      +L  SAPTGSGKTLAF IP++  L        
Sbjct: 82  PIQMQAIPVMLH--------GR------ELLASAPTGSGKTLAFSIPILMQLKQPANKGF 127

Query: 283 RALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADI 342
           RAL++ PT+ELA Q+ +     ++ T  R+ ++      AK+      K  D       I
Sbjct: 128 RALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD-------I 180

Query: 343 VVATPGRLVDHIDQTP-GFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADP 401
           +V TP RL+  + Q P G  L  + +L++DE+D++ +     +                 
Sbjct: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGF----------------- 223

Query: 402 CALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGL 461
                R Q  ++  A   C    +++ +FSAT   + E+  +L L      S G  +  +
Sbjct: 224 -----RDQLASIFLA---CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAV 275

Query: 462 EDTDGD-----GDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFSR-VLCFTNSRE 515
           E  + +      ++GK                    L+ +  +++ GF+  VL F  S E
Sbjct: 276 ETVEQELLFVGSETGK--------------------LLAMRELVKKGFNPPVLVFVQSIE 315

Query: 516 NSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVE 575
            +  LF  +  + G++V    +     QR   +  F  GKI +LI T   ARGID +GV 
Sbjct: 316 RAKELFHEL-IYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVN 374

Query: 576 LVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQE---RRFLRMLTEAGAPELQR- 631
           LV+NYD P     Y+HR+GRT RAG  G+A T   +  +   R    ++ +AG P  +  
Sbjct: 375 LVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYI 434

Query: 632 ---HELSSKLLQPLV--PRYEEALSQLEESVKEERKQR 664
               +L SK  + ++  P   E++S   +   E+ K +
Sbjct: 435 KGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDK 472


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  139 bits (351), Expect = 6e-33
 Identities = 126/458 (27%), Positives = 203/458 (44%), Gaps = 83/458 (18%)

Query: 223 PVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHI 282
           P+Q   IP +L         GR      +L  SAPTGSGKTLAF IP++  L        
Sbjct: 190 PIQMQAIPVMLH--------GR------ELLASAPTGSGKTLAFSIPILMQLKQPANKGF 235

Query: 283 RALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADI 342
           RAL++ PT+ELA Q+ +     ++ T  R+ ++      AK+      K  D       I
Sbjct: 236 RALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD-------I 288

Query: 343 VVATPGRLVDHIDQTP-GFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADP 401
           +V TP RL+  + Q P G  L  + +L++DE+D++ +     +                 
Sbjct: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGF----------------- 331

Query: 402 CALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGL 461
                R Q  ++  A   C    +++ +FSAT   + E+  +L L      S G  +  +
Sbjct: 332 -----RDQLASIFLA---CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAV 383

Query: 462 EDTDGD-----GDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFSR-VLCFTNSRE 515
           E  + +      ++GK                    L+ +  +++ GF+  VL F  S E
Sbjct: 384 ETVEQELLFVGSETGK--------------------LLAMRELVKKGFNPPVLVFVQSIE 423

Query: 516 NSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVE 575
            +  LF  +  + G++V    +     QR   +  F  GKI +LI T   ARGID +GV 
Sbjct: 424 RAKELFHEL-IYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVN 482

Query: 576 LVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQE---RRFLRMLTEAGAPELQR- 631
           LV+NYD P     Y+HR+GRT RAG  G+A T   +  +   R    ++ +AG P  +  
Sbjct: 483 LVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYI 542

Query: 632 ---HELSSKLLQPLV--PRYEEALSQLEESVKEERKQR 664
               +L SK  + ++  P   E++S   +   E+ K +
Sbjct: 543 KGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDK 580


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  138 bits (347), Expect = 2e-32
 Identities = 110/412 (26%), Positives = 188/412 (45%), Gaps = 115/412 (27%)

Query: 251 DLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKVFNIYTDATPL 310
           D+   A TGSGKT AF +P++ ALL      + ALV+ PT+ELA Q+S+ F     +  +
Sbjct: 63  DIIGLAETGSGKTGAFALPILNALLETPQ-RLFALVLTPTRELAFQISEQFEALGSSIGV 121

Query: 311 RVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLII 370
           + +++ G      +  +L +K          I++ATPGRL+DH++ T GF+L+ L++L++
Sbjct: 122 QSAVIVGGIDSMSQSLALAKKP--------HIIIATPGRLIDHLENTKGFNLRALKYLVM 173

Query: 371 DEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLF 430
           DEADR+++   ++ + +++        P D                         +  LF
Sbjct: 174 DEADRILNMDFETEVDKILKVI-----PRD------------------------RKTFLF 204

Query: 431 SATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSS 490
           SAT+T+  +KLQ+  L  P                                  V C++SS
Sbjct: 205 SATMTKKVQKLQRAALKNP----------------------------------VKCAVSS 230

Query: 491 KPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQ 550
           K   V                   E   + ++ +        ++F S+     R   L +
Sbjct: 231 KYQTV-------------------EKLQQYYIFIP-------SKFKSK-----RLGSLNK 259

Query: 551 FEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLL 610
           F+     +L++TD  +RG+D+  V++VVN+D P + + Y+HRVGRTARAG++G+A T + 
Sbjct: 260 FKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT 319

Query: 611 KVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLEESVKEERK 662
           +     F R+           H +  KL  P  P  ++ +  L E V E ++
Sbjct: 320 QYDVELFQRI----------EHLIGKKL--PGFPTQDDEVMMLTERVAEAQR 359


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  133 bits (335), Expect = 5e-31
 Identities = 143/612 (23%), Positives = 250/612 (40%), Gaps = 101/612 (16%)

Query: 37  RLQSRARERQQQREPAQTEAAASTEPATRRRRRPRRRRRVNDAEPGSPEAPQGKRRKADG 96
           R Q+  +E++++ +  +TE  A  E        P+ ++    AEP   +    K +KA  
Sbjct: 24  RKQTEEKEKKEKPKSDKTEEIAEEEETVF----PKAKQVKKKAEPSEVDMNSPKSKKAKK 79

Query: 97  EDAGAESNEEAPGEPSAGSSEEAPGEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGP 156
           ++  ++ N+ +P   S    +E P E    SS+     ++   S E   D P  ++    
Sbjct: 80  KEEPSQ-NDISPKTKSLRKKKE-PIEKKVVSSKTKKVTKNEEPSEEEI-DAPKPKK---- 132

Query: 157 LVPGLVLGGFGKRKAPKVQPFLPRWLAEPNC--------VRRNVTEDLVPIEDIPD---- 204
           +     + G  + K+PK++   P    EP+C           +  E  +P+E        
Sbjct: 133 MKKEKEMNGETREKSPKLKNGFPH--PEPDCNPSEAASEESNSEIEQEIPVEQKEGAFSN 190

Query: 205 --VHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGK 262
             +  +  K L+  G++  FP+QA     +              Y   DL   A TG+GK
Sbjct: 191 FPISEETIKLLKGRGVTFLFPIQAKTFHHV--------------YSGKDLIAQARTGTGK 236

Query: 263 TLAFVIPVVQALLSRVVCHIR-----ALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTG 317
           T +F IP+++ L   +    R      LV+ PT+ELA QVSK F+  T    L V+   G
Sbjct: 237 TFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDIT--KKLSVACFYG 294

Query: 318 QKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMI 377
                 + E +        R   DI+V TPGR+ DHI Q     L +L+ +++DE D+M+
Sbjct: 295 GTPYGGQFERM--------RNGIDILVGTPGRIKDHI-QNGKLDLTKLKHVVLDEVDQML 345

Query: 378 DSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQN 437
           D      +  +++ A++ +   +P  LL           S  CP       +F+      
Sbjct: 346 DMGFADQVEEILSVAYKKDSEDNPQTLL----------FSATCPHW-----VFNVAKKYM 390

Query: 438 PEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLH 497
               +Q+ L   +   T +                      + H  + C  + +  V+  
Sbjct: 391 KSTYEQVDLIGKKTQKTAIT---------------------VEHLAIKCHWTQRAAVIGD 429

Query: 498 LVL----EMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQ 553
           ++       G + + C T          L   +    D           QR + LK F  
Sbjct: 430 VIRVYSGHQGRTIIFCETKKEAQE----LSQNSAIKQDAQSLHGDIPQKQREITLKGFRN 485

Query: 554 GKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQ 613
           G   +L++T+  ARG+D+  V+LV+    P+ + +Y+HR GRT RAG+TG         +
Sbjct: 486 GSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKE 545

Query: 614 ERRFLRMLTEAG 625
           E + +++  +AG
Sbjct: 546 EYQLVQVEQKAG 557


>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
           sapiens]
          Length = 600

 Score =  132 bits (332), Expect = 1e-30
 Identities = 131/470 (27%), Positives = 199/470 (42%), Gaps = 99/470 (21%)

Query: 200 EDIP-DVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPT 258
           E +P  +HP +   LR  G     PVQ+A IP  +              R  D+   A T
Sbjct: 10  ESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFM--------------RNKDVAAEAVT 55

Query: 259 GSGKTLAFVIPVVQALLSR----VVCHIRALVVLPTKELAQQVSKVFNIYTDATP-LRVS 313
           GSGKTLAFVIP+++ LL R        + A+++ PT+ELA Q+ +V + +T   P     
Sbjct: 56  GSGKTLAFVIPILEILLRREEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQI 115

Query: 314 LVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHI-DQTPGFSL----QQLRFL 368
           L  G ++  ++ E   Q+         +I+VATPGRL D    +  G  L    + L  L
Sbjct: 116 LWIGGRNPGEDVERFKQQG-------GNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVL 168

Query: 369 IIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKL 428
           ++DEADR++D   ++                               + +T    +P Q+ 
Sbjct: 169 VLDEADRLLDMGFEA-------------------------------SINTILEFLPKQRR 197

Query: 429 --LFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPC 486
             LFSAT TQ  E L + GL  P   S            G   S     P  L ++Y+ C
Sbjct: 198 TGLFSATQTQEVENLVRAGLRNPVRVSV--------KEKGVAASSAQKTPSRLENYYMVC 249

Query: 487 SLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFL----LVQAFG--------GVDVAE 534
               K   ++H +            N ++  H +F      V+ +G        GV +  
Sbjct: 250 KADEKFNQLVHFL-----------RNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMC 298

Query: 535 FSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVG 594
              +    +R  I  +F + +  +L+ TD  ARGID+  V  V+ YD P     +VHR G
Sbjct: 299 IHGKM-KYKRNKIFMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCG 357

Query: 595 RTARAGKTGQAFTLLLKVQER--RFLRMLTEAGAPELQRHELSSKLLQPL 642
           RTAR G  G A   LL ++E    FL +  +    E++    ++ LL  L
Sbjct: 358 RTARIGHGGSALVFLLPMEESYINFLAINQKCPLQEMKPQRNTADLLPKL 407


>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
           [Homo sapiens]
          Length = 851

 Score =  129 bits (323), Expect = 1e-29
 Identities = 182/663 (27%), Positives = 265/663 (39%), Gaps = 140/663 (21%)

Query: 11  GPDAAAAAGPEGAEAGAHGRARALLERLQSRARERQQQREPAQTEAAAS----TEPATRR 66
           GP     AG      G  G A      L   A        P QT AAA       P T  
Sbjct: 69  GPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHA-------SPTQTMAAADGSLFDNPRTFS 121

Query: 67  RRRPRRRRRVNDAEP----GSPEAPQGKRRKADGEDAGAESNEEAPGEPSAGSSEE--AP 120
           RR P +  R   A       S EAP  KRR         +++ +       G++++  +P
Sbjct: 122 RRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFSP 181

Query: 121 GEPSAGSSEEAPGERSTSASAEAAPDGPALEEAAGPLVPGLVLGGFGKRKAPKVQPFLPR 180
            + S  +S+    ER    ++    + P + E   P+V           K  + + F   
Sbjct: 182 KKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVV-----------KQVQEKVFTSA 230

Query: 181 WLAEPNCVRRNVTEDLVPIEDIPDVHPDLQKQLRAH-GISSYFPVQAAVIPALLESAACG 239
              E                    +HP L   +     +SS   VQ   IP LLE     
Sbjct: 231 AFHELG------------------LHPHLISTINTVLKMSSMTSVQKQSIPVLLE----- 267

Query: 240 FLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIR-----ALVVLPTKELA 294
              GR      D  V + TGSGKTLA+ IPVVQ+L +      R     ALV++PT+ELA
Sbjct: 268 ---GR------DALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELA 318

Query: 295 QQ----VSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRL 350
            Q    V K+   +T   P    L+ G+K   K +++ ++K  +       I+++TPGRL
Sbjct: 319 LQSFDTVQKLLKPFTWIVP--GVLMGGEKR--KSEKARLRKGIN-------ILISTPGRL 367

Query: 351 VDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQA 410
           VDHI  T      +LR+L+ DEADR++D   +  +  V+  A  +E         Q+R  
Sbjct: 368 VDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDI-TVILNAVNAE--------CQKR-- 416

Query: 411 QAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFST-GLAHRGLEDTD---- 465
                          Q +L SATLT+   +L  + LH P   S    +H  L   D    
Sbjct: 417 ---------------QNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQ 461

Query: 466 -----GDGDS-GKYAFPVGLTHH--YVPCSLSSKPLVVLHL---VLEMGFSRVLCFTNSR 514
                  GD    +A P  L  H   VP  L    L    L     E     V+ F++  
Sbjct: 462 EVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCE 521

Query: 515 --ENSHRLFL--LVQAFGGVDVAEFSS--------RYGPG----QRRMILKQFEQGKIQL 558
             E  + LFL  L+ + G     +  S        R   G    +R  + ++F   +  +
Sbjct: 522 LVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGV 581

Query: 559 LISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERRFL 618
           L+ TD  ARG+D+  V  +V Y+AP     Y+HR+GRTAR G  G +  L+L   E  ++
Sbjct: 582 LLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSL-LILAPSEAEYV 640

Query: 619 RML 621
             L
Sbjct: 641 NSL 643


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  127 bits (318), Expect = 4e-29
 Identities = 117/440 (26%), Positives = 194/440 (44%), Gaps = 96/440 (21%)

Query: 213 LRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQ 272
           L+ HG     P+Q   IPA++         GR      DL   A TGSGKT+AF++P+ +
Sbjct: 387 LKKHGYEKPTPIQTQAIPAIMS--------GR------DLIGIAKTGSGKTIAFLLPMFR 432

Query: 273 ALLSRVVCHIR----ALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESL 328
            ++ +          A+++ PT+ELA Q++K    ++    LRV  V G   ++++   L
Sbjct: 433 HIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAEL 492

Query: 329 VQKTADGYRCLADIVVATPGRLVDHIDQTPG--FSLQQLRFLIIDEADRMIDSMHQSWLP 386
            +         A+I+V TPGR++D +    G   +L+++ ++++DEADRM D   +  + 
Sbjct: 493 KRG--------AEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVM 544

Query: 387 RVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGL 446
           R+V       D   P                        Q ++FSAT  +  E L +  L
Sbjct: 545 RIV-------DNVRP----------------------DRQTVMFSATFPRAMEALARRIL 575

Query: 447 HQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFS- 505
            +P     G               G+      +    +      K L +L L+     S 
Sbjct: 576 SKPIEVQVG---------------GRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESG 620

Query: 506 RVLCFTNSRENSHRL--------FLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQ 557
            V+ F + +E++  L        +  +   GG+D  +         R  I+  F+ G  +
Sbjct: 621 SVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYD---------RDSIINDFKNGTCK 671

Query: 558 LLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQER-- 615
           LL++T   ARG+DV+ + LVVNY  P +   YVHR GRT RAG  G A+T + + Q R  
Sbjct: 672 LLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYA 731

Query: 616 ----RFLRMLTEAGAPELQR 631
               + L +   A  P+L++
Sbjct: 732 GDIIKALELSGTAVPPDLEK 751



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 27  AHGRARALLERLQSRARERQQQREPAQTEAAASTEPATRRRRRPRRR-RRVNDAEPGSPE 85
           +  R R  L R +SR R+R ++R  +++          RRR R R R RR   + PG+  
Sbjct: 60  SRSRDRKRLRRSRSRERDRSRERRRSRSR--------DRRRSRSRSRGRRSRSSSPGNKS 111

Query: 86  APQGKRRKADGEDAGAESNEEAPGEPSAGSSEEAPGEPSAGSSEE 130
                R ++  +  G ES++E   +      E+   E  AG+ ++
Sbjct: 112 KKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK---EKDAGNFDQ 153



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 22/104 (21%), Positives = 42/104 (40%), Gaps = 1/104 (0%)

Query: 39  QSRARERQQQREPAQTEAAASTEPATRRRRRPRRRRRVNDAEPGSPEAPQGKRRKADGED 98
           +SR+R+R ++RE +++     +    R+R R R R R  D       +    RR++    
Sbjct: 39  RSRSRDRDRRRERSRSRDKRRSRSRDRKRLR-RSRSRERDRSRERRRSRSRDRRRSRSRS 97

Query: 99  AGAESNEEAPGEPSAGSSEEAPGEPSAGSSEEAPGERSTSASAE 142
            G  S   +PG  S  +   +  +      E +  ++      E
Sbjct: 98  RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKE 141


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  126 bits (316), Expect = 7e-29
 Identities = 110/403 (27%), Positives = 180/403 (44%), Gaps = 45/403 (11%)

Query: 246 GYRPSDLCVSAPTGSGKTLAFVIPVVQAL-----LSRVVCHIR---ALVVLPTKELAQQV 297
           G +  D+   A TGSGKT AF+IP++  +     + R+    +   A+++ PT+ELAQQ+
Sbjct: 425 GLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQI 484

Query: 298 SKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQT 357
            +    +     +R   V G   +++E +          R   +IV+ATPGRL+D ++  
Sbjct: 485 EEETIKFGKPLGIRTVAVIG--GISREDQGF------RLRMGCEIVIATPGRLIDVLENR 536

Query: 358 PGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAAS 417
               L +  ++++DEADRMID   +  + +++     S    D     +    + + A  
Sbjct: 537 Y-LVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTD---EAEDPEKMLANF 592

Query: 418 TCCPQMPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPV 477
                   Q ++F+AT+    E+L +  L +P +   G A +  E  +            
Sbjct: 593 ESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVE------------ 640

Query: 478 GLTHHYVPCSLSSKPLVVLHLVLEMGFSR-VLCFTNSRENSHRLFLLVQAFGGVDVAEFS 536
                 V     S+    L  +LE GF   ++ F N ++    L   ++  G  +     
Sbjct: 641 ----QKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMG-YNACTLH 695

Query: 537 SRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRT 596
              G  QR   L   + G   +L++TD   RGID+Q V +VVNYD  + +  Y+HR+GRT
Sbjct: 696 GGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRT 755

Query: 597 ARAGKTGQAFTLLLKVQERRF-------LRMLTEAGAPELQRH 632
            RAGK+G A T L K     F       L     +  PEL  H
Sbjct: 756 GRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANH 798


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  123 bits (309), Expect = 5e-28
 Identities = 120/408 (29%), Positives = 185/408 (45%), Gaps = 76/408 (18%)

Query: 209 LQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVI 268
           L  Q+R    +   P+Q   +P  L         GR      D+   A TGSGKT AF+ 
Sbjct: 264 LMHQIRKSEYTQPTPIQCQGVPVALS--------GR------DMIGIAKTGSGKTAAFIW 309

Query: 269 PVVQALLSRVVCHIR----ALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKE 324
           P++  ++ +          A++V PT+EL QQ+      +  A  LR   V G  S+ ++
Sbjct: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369

Query: 325 QESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSW 384
            ++L +         A+IVV TPGRL+DH+ +    +LQ++ +L+ DEADRM D M   +
Sbjct: 370 AKALQEG--------AEIVVCTPGRLIDHV-KKKATNLQRVSYLVFDEADRMFD-MGFEY 419

Query: 385 LPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQL 444
             R +A+  + +                             Q LLFSAT  +  EKL + 
Sbjct: 420 QVRSIASHVRPD----------------------------RQTLLFSATFRKKIEKLARD 451

Query: 445 GLHQPRLFSTGLAHRGLEDTDGDGD---SGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLE 501
            L  P     G      ED     +   SG   +   LT   V  + S     VL  V +
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN-WLTRRLVEFTSSGS---VLLFVTK 507

Query: 502 MGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLIS 561
              +  L   N ++  H L LL    G +D +E         R  ++  F++  I +L++
Sbjct: 508 KANAEELA-NNLKQEGHNLGLL---HGDMDQSE---------RNKVISDFKKKDIPVLVA 554

Query: 562 TDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLL 609
           TD  ARG+D+  ++ V+NYD  + + T+ HR+GRT RAG+ G A+TLL
Sbjct: 555 TDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  123 bits (309), Expect = 5e-28
 Identities = 120/408 (29%), Positives = 185/408 (45%), Gaps = 76/408 (18%)

Query: 209 LQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVI 268
           L  Q+R    +   P+Q   +P  L         GR      D+   A TGSGKT AF+ 
Sbjct: 264 LMHQIRKSEYTQPTPIQCQGVPVALS--------GR------DMIGIAKTGSGKTAAFIW 309

Query: 269 PVVQALLSRVVCHIR----ALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKE 324
           P++  ++ +          A++V PT+EL QQ+      +  A  LR   V G  S+ ++
Sbjct: 310 PMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369

Query: 325 QESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSW 384
            ++L +         A+IVV TPGRL+DH+ +    +LQ++ +L+ DEADRM D M   +
Sbjct: 370 AKALQEG--------AEIVVCTPGRLIDHV-KKKATNLQRVSYLVFDEADRMFD-MGFEY 419

Query: 385 LPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQL 444
             R +A+  + +                             Q LLFSAT  +  EKL + 
Sbjct: 420 QVRSIASHVRPD----------------------------RQTLLFSATFRKKIEKLARD 451

Query: 445 GLHQPRLFSTGLAHRGLEDTDGDGD---SGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLE 501
            L  P     G      ED     +   SG   +   LT   V  + S     VL  V +
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWN-WLTRRLVEFTSSGS---VLLFVTK 507

Query: 502 MGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLIS 561
              +  L   N ++  H L LL    G +D +E         R  ++  F++  I +L++
Sbjct: 508 KANAEELA-NNLKQEGHNLGLL---HGDMDQSE---------RNKVISDFKKKDIPVLVA 554

Query: 562 TDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLL 609
           TD  ARG+D+  ++ V+NYD  + + T+ HR+GRT RAG+ G A+TLL
Sbjct: 555 TDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLL 602


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  122 bits (307), Expect = 8e-28
 Identities = 110/406 (27%), Positives = 180/406 (44%), Gaps = 82/406 (20%)

Query: 211 KQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPV 270
           K L+  G++  FP+Q      +              Y   DL   A TG+GKT +F IP+
Sbjct: 150 KLLKGRGVTYLFPIQVKTFGPV--------------YEGKDLIAQARTGTGKTFSFAIPL 195

Query: 271 VQALLSRVVC-----HIRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQ 325
           ++ L             + LV+ PT+ELA QV+K F   T    L V+   G  S     
Sbjct: 196 IERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDIT--RKLSVACFYGGTSY---- 249

Query: 326 ESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWL 385
           +S +    +G     DI+V TPGR+ DH+ Q+    L +LR +++DE D+M+D      +
Sbjct: 250 QSQINHIRNGI----DILVGTPGRIKDHL-QSGRLDLSKLRHVVLDEVDQMLDLGFAEQV 304

Query: 386 PRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLG 445
             ++  +++++   +P                        Q LLFSAT  Q   K+ +  
Sbjct: 305 EDIIHESYKTDSEDNP------------------------QTLLFSATCPQWVYKVAKKY 340

Query: 446 LHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFS 505
           +               E  D  G   + A    + H  + C  S +P V+  ++     S
Sbjct: 341 MKSR-----------YEQVDLVGKMTQKAATT-VEHLAIQCHWSQRPAVIGDVLQVYSGS 388

Query: 506 --RVLCFTNSRENSHRLFLL------VQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQ 557
             R + F  +++N   + +        Q   G D+A+        QR + LK F +G  +
Sbjct: 389 EGRAIIFCETKKNVTEMAMNPHIKQNAQCLHG-DIAQ-------SQREITLKGFREGSFK 440

Query: 558 LLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTG 603
           +L++T+  ARG+D+  V+LV+    PQ + +Y+HR GRT RAG+TG
Sbjct: 441 VLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTG 486


>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
          Length = 547

 Score =  122 bits (306), Expect = 1e-27
 Identities = 112/401 (27%), Positives = 168/401 (41%), Gaps = 89/401 (22%)

Query: 251 DLCVSAPTGSGKTLAFVIPVVQALLSR------VVCHIRALVVLPTKELAQQVSKVFNIY 304
           DL   A TGSGKT A+ IP++Q LL R      V   +R LV++PTKELA+Q   +    
Sbjct: 46  DLLARARTGSGKTAAYAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQL 105

Query: 305 TD--ATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSL 362
               A  +RV+ V+  +    ++  L++K         D+VV TP R++ H+ Q      
Sbjct: 106 ATYCARDVRVANVSAAEDSVSQRAVLMEKP--------DVVVGTPSRILSHLQQDSLKLR 157

Query: 363 QQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQ 422
             L  L++DEAD +             +  F+ E  +  C L +  QA            
Sbjct: 158 DSLELLVVDEADLLF------------SFGFEEELKSLLCHLPRIYQA------------ 193

Query: 423 MPLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHH 482
                 L SAT  ++ + L++L LH P           L+++   G       P  L   
Sbjct: 194 -----FLMSATFNEDVQALKELILHNPVTLK-------LQESQLPG-------PDQLQQF 234

Query: 483 YVPCSLSSKPLVVLHLVLEMGFSR--VLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYG 540
            V C       ++L+ +L++   R   L F N+ E S+RL L ++ F  +     +    
Sbjct: 235 QVVCETEEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFS-IPTCVLNGELP 293

Query: 541 PGQRRMILKQFEQGKIQLLISTDA---------------------------TARGIDVQG 573
              R  I+ QF QG    +I+TDA                            ARGID   
Sbjct: 294 LRSRCHIISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHH 353

Query: 574 VELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQE 614
           V  V+N+D P     Y+HR GRTARA   G   T +L  ++
Sbjct: 354 VSAVLNFDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQ 394


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  121 bits (304), Expect = 2e-27
 Identities = 108/418 (25%), Positives = 180/418 (43%), Gaps = 93/418 (22%)

Query: 209 LQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVI 268
           L   +   G +   PVQ   IP +L         GR      DL   A TGSGKT AF++
Sbjct: 299 LNNNIAKAGYTKLTPVQKYSIPIIL--------AGR------DLMACAQTGSGKTAAFLL 344

Query: 269 PVVQALLSRVVCHIR--------ALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKS 320
           P++  ++   +   R         ++V PT+EL  Q+      ++  T +R  ++ G   
Sbjct: 345 PILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQ 404

Query: 321 LAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSM 380
           L      +VQ          +I+ ATPGRL+D I +     L+Q+++L++DEADRM+D  
Sbjct: 405 LGHSIRQIVQG--------CNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMG 455

Query: 381 HQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMP----LQKLLFSATLTQ 436
               + ++++                             CP MP     Q L+FSAT  +
Sbjct: 456 FGPEMKKLIS-----------------------------CPGMPSKEQRQTLMFSATFPE 486

Query: 437 NPEKLQQLGLHQPRLF----STGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKP 492
             ++L    L    LF      G A R ++ T                   +     SK 
Sbjct: 487 EIQRLAAEFLKSNYLFVAVGQVGGACRDVQQT------------------VLQVGQFSKR 528

Query: 493 LVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRR---MILK 549
             ++ ++  +G  R + F  +++ +      +  F   +    +S +G  ++R     L 
Sbjct: 529 EKLVEILRNIGDERTMVFVETKKKAD----FIATFLCQEKISTTSIHGDREQREREQALG 584

Query: 550 QFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFT 607
            F  GK  +L++T   ARG+D++ V+ V+N+D P  +  YVHR+GRT R G TG+A +
Sbjct: 585 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  121 bits (304), Expect = 2e-27
 Identities = 108/418 (25%), Positives = 180/418 (43%), Gaps = 93/418 (22%)

Query: 209 LQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVI 268
           L   +   G +   PVQ   IP +L         GR      DL   A TGSGKT AF++
Sbjct: 299 LNNNIAKAGYTKLTPVQKYSIPIIL--------AGR------DLMACAQTGSGKTAAFLL 344

Query: 269 PVVQALLSRVVCHIR--------ALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKS 320
           P++  ++   +   R         ++V PT+EL  Q+      ++  T +R  ++ G   
Sbjct: 345 PILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQ 404

Query: 321 LAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSM 380
           L      +VQ          +I+ ATPGRL+D I +     L+Q+++L++DEADRM+D  
Sbjct: 405 LGHSIRQIVQG--------CNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMG 455

Query: 381 HQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMP----LQKLLFSATLTQ 436
               + ++++                             CP MP     Q L+FSAT  +
Sbjct: 456 FGPEMKKLIS-----------------------------CPGMPSKEQRQTLMFSATFPE 486

Query: 437 NPEKLQQLGLHQPRLF----STGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKP 492
             ++L    L    LF      G A R ++ T                   +     SK 
Sbjct: 487 EIQRLAAEFLKSNYLFVAVGQVGGACRDVQQT------------------VLQVGQFSKR 528

Query: 493 LVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRR---MILK 549
             ++ ++  +G  R + F  +++ +      +  F   +    +S +G  ++R     L 
Sbjct: 529 EKLVEILRNIGDERTMVFVETKKKAD----FIATFLCQEKISTTSIHGDREQREREQALG 584

Query: 550 QFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFT 607
            F  GK  +L++T   ARG+D++ V+ V+N+D P  +  YVHR+GRT R G TG+A +
Sbjct: 585 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  121 bits (304), Expect = 2e-27
 Identities = 108/418 (25%), Positives = 180/418 (43%), Gaps = 93/418 (22%)

Query: 209 LQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVI 268
           L   +   G +   PVQ   IP +L         GR      DL   A TGSGKT AF++
Sbjct: 265 LNNNIAKAGYTKLTPVQKYSIPIIL--------AGR------DLMACAQTGSGKTAAFLL 310

Query: 269 PVVQALLSRVVCHIR--------ALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKS 320
           P++  ++   +   R         ++V PT+EL  Q+      ++  T +R  ++ G   
Sbjct: 311 PILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQ 370

Query: 321 LAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSM 380
           L      +VQ          +I+ ATPGRL+D I +     L+Q+++L++DEADRM+D  
Sbjct: 371 LGHSIRQIVQG--------CNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMG 421

Query: 381 HQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMP----LQKLLFSATLTQ 436
               + ++++                             CP MP     Q L+FSAT  +
Sbjct: 422 FGPEMKKLIS-----------------------------CPGMPSKEQRQTLMFSATFPE 452

Query: 437 NPEKLQQLGLHQPRLF----STGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKP 492
             ++L    L    LF      G A R ++ T                   +     SK 
Sbjct: 453 EIQRLAAEFLKSNYLFVAVGQVGGACRDVQQT------------------VLQVGQFSKR 494

Query: 493 LVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRR---MILK 549
             ++ ++  +G  R + F  +++ +      +  F   +    +S +G  ++R     L 
Sbjct: 495 EKLVEILRNIGDERTMVFVETKKKAD----FIATFLCQEKISTTSIHGDREQREREQALG 550

Query: 550 QFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFT 607
            F  GK  +L++T   ARG+D++ V+ V+N+D P  +  YVHR+GRT R G TG+A +
Sbjct: 551 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 608


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  120 bits (302), Expect = 3e-27
 Identities = 118/421 (28%), Positives = 186/421 (44%), Gaps = 86/421 (20%)

Query: 213 LRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQ 272
           L+  GI    P+Q   IP +L         GR      D+   A TGSGKTL F +PV+ 
Sbjct: 196 LKKKGIHHPTPIQIQGIPTILS--------GR------DMIGIAFTGSGKTLVFTLPVIM 241

Query: 273 ALLS---RVVCHIR----ALVVLPTKELAQQVSKVFNIYT-----DATPL-RVSLVTGQK 319
             L    R+    R     L++ P++ELA+Q   +   Y      D++PL R +L  G  
Sbjct: 242 FCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 301

Query: 320 SLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDS 379
           S+ ++ E++        R    ++VATPGRL+D + Q    SL   R+L +DEADRMID 
Sbjct: 302 SVKEQMETI--------RHGVHMMVATPGRLMDLL-QKKMVSLDICRYLALDEADRMIDM 352

Query: 380 MHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPE 439
             +  + R + + F+ +                             Q LLFSAT+ +  +
Sbjct: 353 GFEGDI-RTIFSYFKGQR----------------------------QTLLFSATMPKKIQ 383

Query: 440 KLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLV 499
              +  L +P   + G A             G  +  V     YV        +V L   
Sbjct: 384 NFAKSALVKPVTINVGRA-------------GAASLDVIQEVEYVK---EEAKMVYLLEC 427

Query: 500 LEMGFSRVLCFTNSRENSHRL--FLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQ 557
           L+     VL F   + +   +  +LL++   GV+           +R   ++ F +GK  
Sbjct: 428 LQKTPPPVLIFAEKKADVDAIHEYLLLK---GVEAVAIHGGKDQEERTKAIEAFREGKKD 484

Query: 558 LLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERRF 617
           +L++TD  ++G+D   ++ V+NYD P+ +  YVHR+GRT R+G TG A T + K  +   
Sbjct: 485 VLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESV 544

Query: 618 L 618
           L
Sbjct: 545 L 545


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  117 bits (293), Expect = 3e-26
 Identities = 105/392 (26%), Positives = 172/392 (43%), Gaps = 75/392 (19%)

Query: 223 PVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSR-VVCH 281
           P+Q   IP +L+                D+   A TGSGKT  F++P+ + L +      
Sbjct: 121 PIQRKTIPVILDG--------------KDVVAMARTGSGKTACFLLPMFERLKTHSAQTG 166

Query: 282 IRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLAD 341
            RAL++ PT+ELA Q  K        T L+ +L+ G   +  +  +L +          D
Sbjct: 167 ARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHEN--------PD 218

Query: 342 IVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADP 401
           I++ATPGRLV H+       LQ + +++ DEADR+ +      L  ++A           
Sbjct: 219 IIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIA----------- 266

Query: 402 CALLQRRQAQAVTAASTCCPQMP--LQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHR 459
                               ++P   Q +LFSATL +   +  + GL +P L    +  +
Sbjct: 267 --------------------RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTK 306

Query: 460 GLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLV--LEMGFSRVLCFTNSRENS 517
             E                L   +      +K  V+LHL+  +     + + F  ++ ++
Sbjct: 307 LNEQ---------------LKTSFFLVREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHA 351

Query: 518 HRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELV 577
             L  L+     V  A   S   P  R++ L +F  GK   LI TD  ARG+D+  ++ V
Sbjct: 352 EYLTELLTT-QRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNV 410

Query: 578 VNYDAPQYLRTYVHRVGRTARAGKTGQAFTLL 609
           +NY  P   + ++HRVGR ARAG++G A++L+
Sbjct: 411 INYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  117 bits (293), Expect = 3e-26
 Identities = 105/392 (26%), Positives = 172/392 (43%), Gaps = 75/392 (19%)

Query: 223 PVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLSR-VVCH 281
           P+Q   IP +L+                D+   A TGSGKT  F++P+ + L +      
Sbjct: 121 PIQRKTIPVILDG--------------KDVVAMARTGSGKTACFLLPMFERLKTHSAQTG 166

Query: 282 IRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLAD 341
            RAL++ PT+ELA Q  K        T L+ +L+ G   +  +  +L +          D
Sbjct: 167 ARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHEN--------PD 218

Query: 342 IVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADP 401
           I++ATPGRLV H+       LQ + +++ DEADR+ +      L  ++A           
Sbjct: 219 IIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIA----------- 266

Query: 402 CALLQRRQAQAVTAASTCCPQMP--LQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHR 459
                               ++P   Q +LFSATL +   +  + GL +P L    +  +
Sbjct: 267 --------------------RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTK 306

Query: 460 GLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLV--LEMGFSRVLCFTNSRENS 517
             E                L   +      +K  V+LHL+  +     + + F  ++ ++
Sbjct: 307 LNEQ---------------LKTSFFLVREDTKAAVLLHLLHNVVRPQDQTVVFVATKHHA 351

Query: 518 HRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELV 577
             L  L+     V  A   S   P  R++ L +F  GK   LI TD  ARG+D+  ++ V
Sbjct: 352 EYLTELLTT-QRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNV 410

Query: 578 VNYDAPQYLRTYVHRVGRTARAGKTGQAFTLL 609
           +NY  P   + ++HRVGR ARAG++G A++L+
Sbjct: 411 INYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  115 bits (288), Expect = 1e-25
 Identities = 104/387 (26%), Positives = 173/387 (44%), Gaps = 69/387 (17%)

Query: 251 DLCVSAPTGSGKTLAFVIPVV-----QALLSRVVCHIRALVVLPTKELAQQVSKVFNIYT 305
           D+   A TGSGKTLA+++P +     Q  L R    I  LV+ PT+ELAQQV +V + Y 
Sbjct: 210 DMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPI-CLVLAPTRELAQQVQQVADDYG 268

Query: 306 DATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQL 365
             + L+ + + G      +   L +          +I +ATPGRL+D ++     +L++ 
Sbjct: 269 KCSRLKSTCIYGGAPKGPQIRDLERGV--------EICIATPGRLIDFLESGKT-NLRRC 319

Query: 366 RFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPL 425
            +L++DEADRM+D   +  + ++V       D   P                        
Sbjct: 320 TYLVLDEADRMLDMGFEPQIRKIV-------DQIRP----------------------DR 350

Query: 426 QKLLFSATLTQNPEKLQQLGLHQPRLFSTG-----LAHRGLEDTDGDGDSGKYAFPVGLT 480
           Q L++SAT  +   +L +  L      + G       H  L+  D   +S K        
Sbjct: 351 QTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEK-------- 402

Query: 481 HHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYG 540
                     K + ++  ++    ++ + F  ++     L   ++  G   +     +  
Sbjct: 403 --------DHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQ 454

Query: 541 PGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAG 600
           P +R  +L +F  GK  +LI+TD  +RG+DV+ V+ V+NYD P     YVHR+GRTAR+ 
Sbjct: 455 P-ERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARST 513

Query: 601 KTGQAFTLLLK---VQERRFLRMLTEA 624
             G A+T        Q R  +++L EA
Sbjct: 514 NKGTAYTFFTPGNLKQARELIKVLEEA 540


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  115 bits (288), Expect = 1e-25
 Identities = 104/387 (26%), Positives = 173/387 (44%), Gaps = 69/387 (17%)

Query: 251 DLCVSAPTGSGKTLAFVIPVV-----QALLSRVVCHIRALVVLPTKELAQQVSKVFNIYT 305
           D+   A TGSGKTLA+++P +     Q  L R    I  LV+ PT+ELAQQV +V + Y 
Sbjct: 210 DMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPI-CLVLAPTRELAQQVQQVADDYG 268

Query: 306 DATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQL 365
             + L+ + + G      +   L +          +I +ATPGRL+D ++     +L++ 
Sbjct: 269 KCSRLKSTCIYGGAPKGPQIRDLERGV--------EICIATPGRLIDFLESGKT-NLRRC 319

Query: 366 RFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPL 425
            +L++DEADRM+D   +  + ++V       D   P                        
Sbjct: 320 TYLVLDEADRMLDMGFEPQIRKIV-------DQIRP----------------------DR 350

Query: 426 QKLLFSATLTQNPEKLQQLGLHQPRLFSTG-----LAHRGLEDTDGDGDSGKYAFPVGLT 480
           Q L++SAT  +   +L +  L      + G       H  L+  D   +S K        
Sbjct: 351 QTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEK-------- 402

Query: 481 HHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYG 540
                     K + ++  ++    ++ + F  ++     L   ++  G   +     +  
Sbjct: 403 --------DHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQ 454

Query: 541 PGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAG 600
           P +R  +L +F  GK  +LI+TD  +RG+DV+ V+ V+NYD P     YVHR+GRTAR+ 
Sbjct: 455 P-ERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARST 513

Query: 601 KTGQAFTLLLK---VQERRFLRMLTEA 624
             G A+T        Q R  +++L EA
Sbjct: 514 NKGTAYTFFTPGNLKQARELIKVLEEA 540


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  113 bits (282), Expect = 6e-25
 Identities = 114/431 (26%), Positives = 181/431 (41%), Gaps = 72/431 (16%)

Query: 190 RNVTEDLVPIE--DIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGY 247
           + VT  ++  E   +P+V   L   L+  G     P+Q  +IP          L+GR   
Sbjct: 196 QEVTRPIIDFEHCSLPEV---LNHNLKKSGYEVPTPIQMQMIPV--------GLLGR--- 241

Query: 248 RPSDLCVSAPTGSGKTLAFVIPVVQALLSRVVCHIRALVVLPTKELAQQVSKVFNIYTDA 307
              D+  SA TGSGKT AF++PV+   L        AL++ PT+ELA Q+ +        
Sbjct: 242 ---DILASADTGSGKTAAFLLPVIMRALFESKTP-SALILTPTRELAIQIERQAKELMSG 297

Query: 308 TP-LRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLR 366
            P ++  L+ G   L  +   L Q           +++ATPGRL+D I Q+    L  ++
Sbjct: 298 LPRMKTVLLVGGLPLPPQLYRLQQHVK--------VIIATPGRLLDIIKQS-SVELCGVK 348

Query: 367 FLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQ 426
            +++DEAD M+    Q  +  ++      E+  + C                       Q
Sbjct: 349 IVVVDEADTMLKMGFQQQVLDIL------ENIPNDC-----------------------Q 379

Query: 427 KLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPC 486
            +L SAT+  + E+L    LH P    TG             +       V     +V  
Sbjct: 380 TILVSATIPTSIEQLASQLLHNPVRIITG-------------EKNLPCANVRQIILWVED 426

Query: 487 SLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRM 546
               K L  +    ++    VL F + +  +  L   VQ   G+      S     +R+ 
Sbjct: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486

Query: 547 ILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQAF 606
           ILK   +G  ++++ST    RG+D+  V LVVN+D P  +  YVH++GR  R G+ G A 
Sbjct: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546

Query: 607 TLLLKVQERRF 617
           T +    +R F
Sbjct: 547 TFINNNSKRLF 557


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  110 bits (275), Expect = 4e-24
 Identities = 109/440 (24%), Positives = 183/440 (41%), Gaps = 96/440 (21%)

Query: 189 RRNVTEDLVPIEDIPDVHPDLQKQLRAHGISSYFPVQAAVIPALLESAACGFLVGRGGYR 248
           +R +       +D    +P++ + ++  G     P+Q+   P +L+              
Sbjct: 233 KRPIPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGI------------ 280

Query: 249 PSDLCVSAPTGSGKTLAFVIP-----VVQALLSRVVCHIRALVVLPTKELAQQVSKVFNI 303
             DL   A TG+GKTL +++P     V+Q  L         LV+ PT+ELA QV      
Sbjct: 281 --DLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCK 338

Query: 304 YTDATPLRVSLVTGQKSLAKEQESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQ 363
           Y+    LR   V G  +  ++ E L +          DI++ATPGRL D +  +   +L+
Sbjct: 339 YS-YKGLRSVCVYGGGNRDEQIEELKKGV--------DIIIATPGRLND-LQMSNFVNLK 388

Query: 364 QLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQM 423
            + +L++DEAD+M+D   +  + ++               LL  R  +            
Sbjct: 389 NITYLVLDEADKMLDMGFEPQIMKI---------------LLDVRPDR------------ 421

Query: 424 PLQKLLFSATLTQNPEKLQQLGLHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHY 483
             Q ++ SAT   +  +L Q  L +P +   G                        T   
Sbjct: 422 --QTVMTSATWPHSVHRLAQSYLKEPMIVYVG------------------------TLDL 455

Query: 484 VPCSLSSKPLVVLHLVLEMGFSRVLCFTNSRENSHRLFLLVQA------------FGGVD 531
           V  S   + ++V     E  +S +  F  S  ++ ++ + V               G + 
Sbjct: 456 VAVSSVKQNIIVT--TEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNIS 513

Query: 532 VAEFSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVH 591
           V           R   L+ F+ GK+++LI+TD  +RG+DV  V  V N+D P+ +  YVH
Sbjct: 514 VESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVH 573

Query: 592 RVGRTARAGKTGQAFTLLLK 611
           R+GRT RAG+TG + T L +
Sbjct: 574 RIGRTGRAGRTGVSITTLTR 593


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  105 bits (262), Expect = 1e-22
 Identities = 104/403 (25%), Positives = 168/403 (41%), Gaps = 86/403 (21%)

Query: 223 PVQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALLS------ 276
           PVQ   IP + E                DL   A TGSGKT AF++P++  + S      
Sbjct: 205 PVQKHAIPIIKEKR--------------DLMACAQTGSGKTAAFLLPILSQIYSDGPGEA 250

Query: 277 -----------RVVCHIRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQ 325
                      R   +  +LV+ PT+ELA Q+ +    ++  + +R  +V G   + ++ 
Sbjct: 251 LRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQI 310

Query: 326 ESLVQKTADGYRCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWL 385
             L +           ++VATPGRLVD +++     L   ++L++DEADRM+D   +  +
Sbjct: 311 RDLERG--------CHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFEPQI 361

Query: 386 PRVVAAAFQSEDPADPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLG 445
            R+V                            T  P+     ++FSAT  +  + L +  
Sbjct: 362 RRIVEQ-------------------------DTMPPKGVRHTMMFSATFPKEIQMLARDF 396

Query: 446 LHQPRLFSTGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGF- 504
           L +    + G      E+               +T   V    S K   +L L+   G  
Sbjct: 397 LDEYIFLAVGRVGSTSEN---------------ITQKVVWVEESDKRSFLLDLLNATGKD 441

Query: 505 SRVLCFTNSRENSHRL--FLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLIST 562
           S  L F  +++ +  L  FL  + +    +    S+     R   L QF  GK  +L++T
Sbjct: 442 SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR---DREEALHQFRSGKSPILVAT 498

Query: 563 DATARGIDVQGVELVVNYDAPQYLRTYVHRVGRTARAGKTGQA 605
              ARG+D+  V+ V+N+D P  +  YVHR+GRT R G  G A
Sbjct: 499 AVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLA 541


>gi|8922976 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Homo sapiens]
          Length = 540

 Score =  103 bits (256), Expect = 7e-22
 Identities = 109/388 (28%), Positives = 173/388 (44%), Gaps = 60/388 (15%)

Query: 224 VQAAVIPALLESAACGFLVGRGGYRPSDLCVSAPTGSGKTLAFVIPVVQALL------SR 277
           VQ++ IP+LL              R   +  +A TGSGKTL++++P++Q LL      S 
Sbjct: 154 VQSSTIPSLL--------------RGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSL 199

Query: 278 VVCHIRALVVLPTKELAQQVSKVFNIYTDATPLRVSLVTGQKSLAKEQESLVQKTADGYR 337
            +   R LV++P++ELAQQV  V      +  L V  + G   + + +  L ++ +    
Sbjct: 200 PIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPS---- 255

Query: 338 CLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFQSED 397
             AD++VATPG L   + ++   SL+QL FL++DEAD ++D      +  ++  +  +E 
Sbjct: 256 --ADVLVATPGALWKAL-KSRLISLEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEG 312

Query: 398 PA---DPCALLQRRQAQAVTAASTCCPQMPLQKLLFSATLTQNPEKLQQLGLH--QPRLF 452
           PA   DP       +AQ V   +T  P+  + +LL           +    LH   P + 
Sbjct: 313 PADLEDPF----NPKAQLVLVGATF-PE-GVGQLLNKVASPDAVTTITSSKLHCIMPHVK 366

Query: 453 STGLAHRGLEDTDGDGDSGKYAFPVGLTHHYVPCSLSSKPLVVLHLVLEMGFSRVLCFTN 512
            T L  +G +         K A  V +  H      +                 VL F N
Sbjct: 367 QTFLRLKGAD---------KVAELVHILKHRDRAERTGPS------------GTVLVFCN 405

Query: 513 SRENSHRLFLLVQAFGGVDVAEFSSRYGPGQRRMILKQFEQGKIQLLISTDATARGIDVQ 572
           S    + L  ++     +       +     R  I + F++    +L+ TD  +RG+D  
Sbjct: 406 SSSTVNWLGYILDDHK-IQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTDIASRGLDST 464

Query: 573 GVELVVNYDAPQYLRTYVHRVGRTARAG 600
           GVELVVNYD P  L+ Y+HR GR  R G
Sbjct: 465 GVELVVNYDFPPTLQDYIHRAGRVGRVG 492


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,754,001
Number of Sequences: 37866
Number of extensions: 1347416
Number of successful extensions: 15522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 1049
Number of HSP's that attempted gapping in prelim test: 10986
Number of HSP's gapped (non-prelim): 4560
length of query: 666
length of database: 18,247,518
effective HSP length: 109
effective length of query: 557
effective length of database: 14,120,124
effective search space: 7864909068
effective search space used: 7864909068
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.