Guide to the Human Genome
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Search of human proteins with 150378533

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
         (1102 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]           2272   0.0  
gi|71774197 ubiquitin specific protease 47 [Homo sapiens]             184   5e-46
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]                  164   4e-40
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]   151   4e-36
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]   149   1e-35
gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [...   124   6e-28
gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [...   124   6e-28
gi|110347427 ubiquitin specific protease 34 [Homo sapiens]            123   8e-28
gi|149192845 ubiquitin specific protease 24 [Homo sapiens]            119   2e-26
gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]    118   3e-26
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]                 110   6e-24
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap...   109   2e-23
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi...   109   2e-23
gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ...    94   7e-19
gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo ...    94   9e-19
gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ...    94   9e-19
gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo ...    94   9e-19
gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo ...    94   9e-19
gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ...    93   1e-18
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]             93   1e-18
gi|32313610 ubiquitin specific protease 18 [Homo sapiens]              92   2e-18
gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ...    92   4e-18
gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo ...    92   4e-18
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ...    91   5e-18
gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    91   5e-18
gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    91   5e-18
gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    91   5e-18
gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    91   5e-18
gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    91   5e-18
gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Ho...    91   5e-18

>gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
          Length = 1102

 Score = 2272 bits (5887), Expect = 0.0
 Identities = 1102/1102 (100%), Positives = 1102/1102 (100%)

Query: 1    MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME 60
            MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME
Sbjct: 1    MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME 60

Query: 61   DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ 120
            DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ
Sbjct: 61   DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ 120

Query: 121  CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE 180
            CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE
Sbjct: 121  CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE 180

Query: 181  KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK 240
            KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK
Sbjct: 181  KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK 240

Query: 241  AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC 300
            AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC
Sbjct: 241  AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC 300

Query: 301  RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI 360
            RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI
Sbjct: 301  RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI 360

Query: 361  FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK 420
            FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK
Sbjct: 361  FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK 420

Query: 421  INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF 480
            INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF
Sbjct: 421  INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF 480

Query: 481  DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL 540
            DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL
Sbjct: 481  DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL 540

Query: 541  VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS 600
            VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS
Sbjct: 541  VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS 600

Query: 601  SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI 660
            SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI
Sbjct: 601  SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI 660

Query: 661  FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM 720
            FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM
Sbjct: 661  FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM 720

Query: 721  CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL 780
            CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL
Sbjct: 721  CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL 780

Query: 781  PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF 840
            PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF
Sbjct: 781  PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF 840

Query: 841  KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN 900
            KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN
Sbjct: 841  KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN 900

Query: 901  SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE 960
            SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE
Sbjct: 901  SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE 960

Query: 961  CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV 1020
            CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV
Sbjct: 961  CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV 1020

Query: 1021 MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD 1080
            MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD
Sbjct: 1021 MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD 1080

Query: 1081 HFNKAPKRSRYTYLEKAIKIHN 1102
            HFNKAPKRSRYTYLEKAIKIHN
Sbjct: 1081 HFNKAPKRSRYTYLEKAIKIHN 1102


>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
          Length = 1287

 Score =  184 bits (466), Expect = 5e-46
 Identities = 107/249 (42%), Positives = 146/249 (58%), Gaps = 10/249 (4%)

Query: 207 SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEG--DDSSKSVPLALQRVF 264
           +K  TGYVGL NQ  TCY+NSLLQTLF T + R A+Y    E   +D   S+P  LQR+F
Sbjct: 93  NKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLF 152

Query: 265 YELQHSDK-PVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKL 323
             LQ S K  + T  +T+SFGW++ +++ QHDVQELCRV+ D +E K K T     I +L
Sbjct: 153 VLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINEL 212

Query: 324 FRGKMVSYIQCKEVDYRSDRREDYYDIQLSIK--GKKNIFESFVD----YVAVEQLDGDN 377
           ++GK+  Y++C E  Y   R + Y DI L I+  G    F S  +    ++  E LDG N
Sbjct: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272

Query: 378 KYDAGEHGLQ-EAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF 436
           +Y       + +A KG++FL  P +L LQL RF +D  T   IK+NDR  FPE+L +  F
Sbjct: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332

Query: 437 LQKTDPKDP 445
           +   D K P
Sbjct: 333 IDVEDEKSP 341



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 22/168 (13%)

Query: 443 KDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHD 502
           K+   Y L +V+VHSG   GGHY   +    D +W  F+D  VSR T+E+ I+  +GG  
Sbjct: 394 KNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQED-IKKTHGGSS 452

Query: 503 D-----DLSVRHCTNAYMLVY-----IRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEA 552
                   +    TNAYML+Y      R +K  EV       + P+ +   +Q+E+ +E 
Sbjct: 453 GSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEV------DEYPEHIKNLVQKERELEE 506

Query: 553 QKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS 600
           Q++++R+      ++++     FC H    +  E K++    K LK +
Sbjct: 507 QEKRQREIERNTCKIKL-----FCLHPTKQVMMENKLEVHKDKTLKEA 549


>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
          Length = 1247

 Score =  164 bits (415), Expect = 4e-40
 Identities = 122/412 (29%), Positives = 201/412 (48%), Gaps = 48/412 (11%)

Query: 208 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEG----------DDSSKSVP 257
           ++ T   G++NQG TCY+NSLLQTL FT + R+A++ +  E           D   + +P
Sbjct: 47  REFTNLSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDAKVRIIP 106

Query: 258 LALQRVFYELQHSDKPVG-TKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCV 316
           L LQR+F +L   D+    T  LT SFGW + +   QHDVQEL R+L   +E  + GT  
Sbjct: 107 LQLQRLFAQLLLLDQEAASTADLTDSFGWTSNEEMRQHDVQELNRILFSALETSLVGTSG 166

Query: 317 EGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVD-YVAVEQLDG 375
              I +L+ G +V+ I CKE    S+R+ED+ D+ +++K    + ++  + YV  E  D 
Sbjct: 167 HDLIYRLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVKNVSGLEDALWNMYVEEEVFDC 226

Query: 376 DNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLD 434
           DN Y  G    L +A K  K   LPP L + L+RF +D    +  K    + FP ++ L 
Sbjct: 227 DNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLK 286

Query: 435 EFLQKTDPKD-PANYILHAVLVHSGDNHGGHYVVYLNPKGD-GKWCKFDDDVVSRCTKEE 492
            F ++++  D    Y L +V++H G  +GGHY VY+      G W +F ++       + 
Sbjct: 287 PFCEQSELDDLEYIYDLFSVIIHKGGCYGGHYHVYIKDVDHLGNW-QFQEE-------KS 338

Query: 493 AIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVER--LQEEKRI 550
             + N      +  + H       + + E+ L  V Q      + Q+L+++  +   K+ 
Sbjct: 339 KPDVNLKDLQSEEEIDHPLMILKAILLEENNLIPVDQ------LGQKLLKKIGISWNKKY 392

Query: 551 EAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSL 602
             Q    R+   L+ Q+ +++ D+                 +  ++LKNSSL
Sbjct: 393 RKQHGPLRKFLQLHSQIFLLSSDE-----------------STVRLLKNSSL 427


>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
          Length = 1035

 Score =  151 bits (381), Expect = 4e-36
 Identities = 113/409 (27%), Positives = 199/409 (48%), Gaps = 47/409 (11%)

Query: 206 DSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPT-------------EGDDS 252
           + +K   +VGL N GATCY+N+ LQ  F   +LR+A+Y+ P+             E D  
Sbjct: 81  ERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYE 140

Query: 253 SKSVPLALQRVFYELQHSDKP-VGTKKLTKSFGWETLDSFMQHDVQELCRV---LLDNVE 308
            +++   LQ +F  LQ+S++  +      K+ G   LD+  Q D QE  ++   LL++  
Sbjct: 141 PQTICEHLQYLFALLQNSNRRYIDPSGFVKALG---LDTGQQQDAQEFSKLFMSLLEDTL 197

Query: 309 NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYV 368
           +K K   V   + + F G+      C +    S     +Y+++L+I+G K + +   +++
Sbjct: 198 SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFL 257

Query: 369 AVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEF 427
             E+L+GDN+Y        Q A + ++ L+LP  L+LQLMRF++D QT    K+N    F
Sbjct: 258 KEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGF 317

Query: 428 PEQLPLDEFLQKTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVS 486
            E L ++ +++         Y L AVL+H G   + GHY+ ++     G+W KF+D+ + 
Sbjct: 318 SEILDMEPYVEHKG--GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIE 375

Query: 487 RCTKEE---AIEHNYGGHDDDLSVR-------HCT-NAYMLVYIRES--------KLSEV 527
           +   ++    IE +        + +       HC+ NAYMLVY  ++        ++   
Sbjct: 376 KMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAF 435

Query: 528 LQAVTDHD---IPQQLVERLQEEKR-IEAQKRKERQEAHLYMQVQIVAE 572
           LQ + D D     +  +E  +  K+ ++  K K  +   LY ++   AE
Sbjct: 436 LQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAE 484


>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
          Length = 485

 Score =  149 bits (377), Expect = 1e-35
 Identities = 111/404 (27%), Positives = 197/404 (48%), Gaps = 47/404 (11%)

Query: 206 DSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPT-------------EGDDS 252
           + +K   +VGL N GATCY+N+ LQ  F   +LR+A+Y+ P+             E D  
Sbjct: 81  ERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYE 140

Query: 253 SKSVPLALQRVFYELQHSDKP-VGTKKLTKSFGWETLDSFMQHDVQELCRV---LLDNVE 308
            +++   LQ +F  LQ+S++  +      K+ G   LD+  Q D QE  ++   LL++  
Sbjct: 141 PQTICEHLQYLFALLQNSNRRYIDPSGFVKALG---LDTGQQQDAQEFSKLFMSLLEDTL 197

Query: 309 NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYV 368
           +K K   V   + + F G+      C +    S     +Y+++L+I+G K + +   +++
Sbjct: 198 SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFL 257

Query: 369 AVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEF 427
             E+L+GDN+Y        Q A + ++ L+LP  L+LQLMRF++D QT    K+N    F
Sbjct: 258 KEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGF 317

Query: 428 PEQLPLDEFLQKTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVS 486
            E L ++ +++         Y L AVL+H G   + GHY+ ++     G+W KF+D+ + 
Sbjct: 318 SEILDMEPYVEHKG--GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIE 375

Query: 487 RCTKEE---AIEHNYGGHDDDLSVR-------HCT-NAYMLVYIRES--------KLSEV 527
           +   ++    IE +        + +       HC+ NAYMLVY  ++        ++   
Sbjct: 376 KMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAF 435

Query: 528 LQAVTDHD---IPQQLVERLQEEKR-IEAQKRKERQEAHLYMQV 567
           LQ + D D     +  +E  +  K+ ++  K K  +   LY ++
Sbjct: 436 LQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRL 479


>gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo
            sapiens]
          Length = 2554

 Score =  124 bits (310), Expect = 6e-28
 Identities = 115/440 (26%), Positives = 179/440 (40%), Gaps = 98/440 (22%)

Query: 212  GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY------------MMPTEGDDSSKSVPLA 259
            G+VGLKN GATCYMNS++Q L+    +R  +             M   E  D+  +V   
Sbjct: 1555 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1614

Query: 260  LQRVFYELQHSDKPVGTKK-------------LTKSFG---------------------W 285
                 Y  Q  DKP  +K              L   FG                     W
Sbjct: 1615 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLW 1674

Query: 286  -ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRR 344
             E ++   QHD  E    L+D+++  +K       + K+  G       C+   +R +  
Sbjct: 1675 GEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECE 1734

Query: 345  EDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLH 403
            E +  + + I+  +N+ +S   YV  + L+G N Y   +   + +  K +    LPPVL 
Sbjct: 1735 ESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLA 1794

Query: 404  LQLMRFMYDPQTDQNIKINDRFEFPEQL-------------------PLDEFLQKTDPKD 444
            +QL RF YD + +  IK ND FEFP +L                   P  + +Q+++  +
Sbjct: 1795 IQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSE 1854

Query: 445  -----PANYILHAVLVHSGDNHGGHYVVYLNPK--GDG---KWCKFDDDVVSRC------ 488
                    Y L  VLVHSG   GGHY  Y+  +  GDG   +W KFDD  V+ C      
Sbjct: 1855 SETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDE 1914

Query: 489  -TKEEAIEHNYGGHDDDLSVRHCT--------NAYMLVYIRESKL---SEVLQAVTDHDI 536
              K +     Y G   D  ++  +        NAY+L Y R   +    E+++ +++  I
Sbjct: 1915 EMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAI 1974

Query: 537  ---PQQLVERLQEEKRIEAQ 553
               P Q++     E+ +  Q
Sbjct: 1975 TTRPHQIIMPSAIERSVRKQ 1994


>gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo
            sapiens]
          Length = 2570

 Score =  124 bits (310), Expect = 6e-28
 Identities = 115/440 (26%), Positives = 179/440 (40%), Gaps = 98/440 (22%)

Query: 212  GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY------------MMPTEGDDSSKSVPLA 259
            G+VGLKN GATCYMNS++Q L+    +R  +             M   E  D+  +V   
Sbjct: 1555 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1614

Query: 260  LQRVFYELQHSDKPVGTKK-------------LTKSFG---------------------W 285
                 Y  Q  DKP  +K              L   FG                     W
Sbjct: 1615 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLW 1674

Query: 286  -ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRR 344
             E ++   QHD  E    L+D+++  +K       + K+  G       C+   +R +  
Sbjct: 1675 GEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECE 1734

Query: 345  EDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLH 403
            E +  + + I+  +N+ +S   YV  + L+G N Y   +   + +  K +    LPPVL 
Sbjct: 1735 ESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLA 1794

Query: 404  LQLMRFMYDPQTDQNIKINDRFEFPEQL-------------------PLDEFLQKTDPKD 444
            +QL RF YD + +  IK ND FEFP +L                   P  + +Q+++  +
Sbjct: 1795 IQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSE 1854

Query: 445  -----PANYILHAVLVHSGDNHGGHYVVYLNPK--GDG---KWCKFDDDVVSRC------ 488
                    Y L  VLVHSG   GGHY  Y+  +  GDG   +W KFDD  V+ C      
Sbjct: 1855 SETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDE 1914

Query: 489  -TKEEAIEHNYGGHDDDLSVRHCT--------NAYMLVYIRESKL---SEVLQAVTDHDI 536
              K +     Y G   D  ++  +        NAY+L Y R   +    E+++ +++  I
Sbjct: 1915 EMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAI 1974

Query: 537  ---PQQLVERLQEEKRIEAQ 553
               P Q++     E+ +  Q
Sbjct: 1975 TTRPHQIIMPSAIERSVRKQ 1994


>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
          Length = 3546

 Score =  123 bits (309), Expect = 8e-28
 Identities = 103/372 (27%), Positives = 163/372 (43%), Gaps = 50/372 (13%)

Query: 195  VQADAPHGVAWDSKKHTG------YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTE 248
            +Q+ AP+   WD   H        +VGL N GATCY+ S +Q L+   + R+AV+     
Sbjct: 1871 MQSHAPY--KWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYS 1928

Query: 249  GDDSSKSVPLALQRVFYELQHSD-KPVGTKKLTKSFGW--ETLDSFMQHDVQELCRVLLD 305
             D   K+  L LQ++F  L  S+ K    +   K++    + L++  Q D+ E    L+ 
Sbjct: 1929 EDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLIT 1988

Query: 306  NVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFV 365
             +E       ++ T+  LF G + + +   + ++ S   E++Y ++  +   KNI+ES  
Sbjct: 1989 KIEEMSPE--LKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLD 2046

Query: 366  DYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDR 424
            +    + L+GDN Y     G +  AEK   F  LP +L    MR+ ++  T    K+N  
Sbjct: 2047 EVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTH 2106

Query: 425  FEFPEQLPL-----DEFLQKTDPK-------------DPANYILHAVLVHSGDNHGGHYV 466
            F FP +L +     D  + K++ K             +   Y L  V VH+G   GGHY 
Sbjct: 2107 FSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYY 2166

Query: 467  VYL----NPKG--DGKWCKFDD---------DVVSRCTKEEAIEHNYGGHDD---DLSVR 508
             ++    NP    + KW  F+D          + S C   E     Y    D   D S  
Sbjct: 2167 SFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFE 2226

Query: 509  HCTNAYMLVYIR 520
               +AYML Y R
Sbjct: 2227 KTHSAYMLFYKR 2238


>gi|149192845 ubiquitin specific protease 24 [Homo sapiens]
          Length = 2460

 Score =  119 bits (297), Expect = 2e-26
 Identities = 101/366 (27%), Positives = 162/366 (44%), Gaps = 52/366 (14%)

Query: 206  DSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFY 265
            DS+  +G+VGL+N GATCYMN++ Q L+    L +++  +  + D+   SV   +Q +F 
Sbjct: 1521 DSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFG 1580

Query: 266  ELQHSD----KPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIP 321
             L  S      P    K+ K +  E L    Q D  E    L+D ++  +K    +    
Sbjct: 1581 HLMESKLQYYVPENFWKIFKMWNKE-LYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFK 1639

Query: 322  KLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDA 381
              F+G       CK+  +R +R E +  + L +   +++  S   +V  E L+G N Y  
Sbjct: 1640 NTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYC 1699

Query: 382  GEHGLQEAEKGVK---FLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF-- 436
             +   +E    VK     +LP VL + LMRF +D ++ ++IK +++  FP  L ++ +  
Sbjct: 1700 EK--CKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTV 1757

Query: 437  --LQKTDPKDPA-----------------------NYILHAVLVHSGDNHGGHYVVYLNP 471
              + + D                            NY L  V+VHSG  H GHY  ++  
Sbjct: 1758 SGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKD 1817

Query: 472  K---GDGKWCKFDDDVVSRC-TKEEAIEHNYGGHDDDLSV-----------RHCTNAYML 516
            +   G GKW KF+D V+      +E +E+   G +    V           R   NAYML
Sbjct: 1818 RRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYML 1877

Query: 517  VYIRES 522
             Y R S
Sbjct: 1878 FYQRVS 1883


>gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]
          Length = 2555

 Score =  118 bits (296), Expect = 3e-26
 Identities = 114/442 (25%), Positives = 178/442 (40%), Gaps = 97/442 (21%)

Query: 212  GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY------------MMPTEGDDSSKSVPLA 259
            G+VGLKN GATCYMNS++Q L+    +R ++             M   E  DS  +V   
Sbjct: 1557 GFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPR 1616

Query: 260  LQRVFYELQHSDKPVGTKK-------------LTKSFG---------------------W 285
                 Y  Q  DKP  +K              L   FG                     W
Sbjct: 1617 DDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLW 1676

Query: 286  -ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRR 344
             E ++   QHD  E    L+D+++  +K       + K+  G       C+   +R +  
Sbjct: 1677 GEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECE 1736

Query: 345  EDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLH 403
            E +  + + I+  +N+ +S   Y+  + L+G N Y   +   + +  K +    LP VL 
Sbjct: 1737 ESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLA 1796

Query: 404  LQLMRFMYDPQTDQNIKINDRFEFPEQLPL-------------------DEFLQKTDPKD 444
            +QL RF YD + +  IK ND FEFP +L +                   +E +++ +  D
Sbjct: 1797 IQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSD 1856

Query: 445  -----PANYILHAVLVHSGDNHGGHYVVYL---NPKGD--GKWCKFDDDVVSRC------ 488
                    Y L  VLVHSG   GGHY  Y+   N K D    W KFDD  V+ C      
Sbjct: 1857 NETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDE 1916

Query: 489  -TKEEAIEHNYGGHDDDLSVRHCT--------NAYMLVYIRESKL---SEVLQAVTDHDI 536
              K +     Y G   D  ++  +        NAY+L Y +   +    E+++ +++  I
Sbjct: 1917 EMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTI 1976

Query: 537  --PQQLVERLQEEKRIEAQKRK 556
              P Q++     E+ +  Q  K
Sbjct: 1977 ARPHQIIMSPAIERSVRKQNVK 1998


>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
          Length = 370

 Score =  110 bits (276), Expect = 6e-24
 Identities = 98/337 (29%), Positives = 152/337 (45%), Gaps = 39/337 (11%)

Query: 213 YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDK 272
           Y GL N G TCY NS+LQ L+F    R+ V    ++     +S+   L  +F+ +    K
Sbjct: 38  YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQ-PRKKESLLTCLADLFHSIATQKK 96

Query: 273 PVGT---KKLTKSFGWET--LDSFMQHDVQELCRVLLD---------------------- 305
            VG    KK       E    D++MQ D  E    LL+                      
Sbjct: 97  KVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG 156

Query: 306 NVENKMKGTCVEGT-IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESF 364
           N++N+   +  + T + ++F+G + +  +C   +  S + ED+ D+ + ++   +I    
Sbjct: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCL 216

Query: 365 VDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKIND 423
             +   E L  + KY   E    QEA K +K   LP +L L L RF Y  Q  +  K++ 
Sbjct: 217 RGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSY 276

Query: 424 RFEFPEQLPLDEFLQKTDPKDPAN-YILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFD 481
           R  FP +L L  F    D  +P   Y L AV+VH G   + GHY+  +  K    W  FD
Sbjct: 277 RVVFPLELRL--FNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIV--KSHDFWLLFD 332

Query: 482 DDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518
           DD+V +    +AIE  Y G   D+S ++  + Y+L Y
Sbjct: 333 DDIVEK-IDAQAIEEFY-GLTSDIS-KNSESGYILFY 366


>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
           sapiens]
          Length = 359

 Score =  109 bits (272), Expect = 2e-23
 Identities = 96/337 (28%), Positives = 150/337 (44%), Gaps = 39/337 (11%)

Query: 213 YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDK 272
           Y GL N G TCY NS+LQ L+F    R+ V     +     +++   L  +F+ +    K
Sbjct: 27  YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ-QKKKENLLTCLADLFHSIATQKK 85

Query: 273 PVGT---KKLTKSFGWET--LDSFMQHDVQELCRVLLDNV---------ENKMKGTCVEG 318
            VG    KK       E    D++MQ D  E    LL+ +         + K  G    G
Sbjct: 86  KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 145

Query: 319 T--------------IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESF 364
                          + ++F+G + +  +C   +  S + ED+ D+ + ++   +I    
Sbjct: 146 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCL 205

Query: 365 VDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKIND 423
            D+   E L  + KY        QEA+K ++   LP +L L L RF Y  Q  +  K++ 
Sbjct: 206 RDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSY 265

Query: 424 RFEFPEQLPLDEFLQKTDPKD-PANYILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFD 481
           R  FP +L L  F   +D  +    Y L AV+VH G   + GHY+  +  K  G W  FD
Sbjct: 266 RVVFPLELRL--FNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIV--KSHGFWLLFD 321

Query: 482 DDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518
           DD+V +    +AIE  Y G   D+S ++  + Y+L Y
Sbjct: 322 DDIVEK-IDAQAIEEFY-GLTSDIS-KNSESGYILFY 355


>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
           sapiens]
          Length = 366

 Score =  109 bits (272), Expect = 2e-23
 Identities = 96/337 (28%), Positives = 150/337 (44%), Gaps = 39/337 (11%)

Query: 213 YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDK 272
           Y GL N G TCY NS+LQ L+F    R+ V     +     +++   L  +F+ +    K
Sbjct: 34  YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ-QKKKENLLTCLADLFHSIATQKK 92

Query: 273 PVGT---KKLTKSFGWET--LDSFMQHDVQELCRVLLDNV---------ENKMKGTCVEG 318
            VG    KK       E    D++MQ D  E    LL+ +         + K  G    G
Sbjct: 93  KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 152

Query: 319 T--------------IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESF 364
                          + ++F+G + +  +C   +  S + ED+ D+ + ++   +I    
Sbjct: 153 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCL 212

Query: 365 VDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKIND 423
            D+   E L  + KY        QEA+K ++   LP +L L L RF Y  Q  +  K++ 
Sbjct: 213 RDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSY 272

Query: 424 RFEFPEQLPLDEFLQKTDPKD-PANYILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFD 481
           R  FP +L L  F   +D  +    Y L AV+VH G   + GHY+  +  K  G W  FD
Sbjct: 273 RVVFPLELRL--FNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIV--KSHGFWLLFD 328

Query: 482 DDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518
           DD+V +    +AIE  Y G   D+S ++  + Y+L Y
Sbjct: 329 DDIVEK-IDAQAIEEFY-GLTSDIS-KNSESGYILFY 362


>gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo
           sapiens]
          Length = 559

 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 95/360 (26%), Positives = 161/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI+   ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIDKNVQYPECLDMKLYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           +T+   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QTN-SGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo
           sapiens]
          Length = 530

 Score = 93.6 bits (231), Expect = 9e-19
 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +  LT   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKMLTLLTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo
           sapiens]
          Length = 530

 Score = 93.6 bits (231), Expect = 9e-19
 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           +T+   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QTN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo
           sapiens]
          Length = 530

 Score = 93.6 bits (231), Expect = 9e-19
 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +  LT   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKMLTLLTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo
           sapiens]
          Length = 530

 Score = 93.6 bits (231), Expect = 9e-19
 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           +T+   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QTN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo
           sapiens]
          Length = 530

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 95/343 (27%), Positives = 153/343 (44%), Gaps = 46/343 (13%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           +T+   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QTN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL 540
                          AY+L YI++S+     ++V+    P+ L
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRAL 394


>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
          Length = 1316

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 88/333 (26%), Positives = 144/333 (43%), Gaps = 41/333 (12%)

Query: 205 WDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQ--- 261
           W      G  GL+N G TC+ N+ LQ L +T  L  A YM+  E   +  +    +    
Sbjct: 103 WQQTHRVG-AGLQNLGNTCFANAALQCLTYTPPL--ANYMLSHEHSKTCHAEGFCMMCTM 159

Query: 262 --RVFYELQHSD---KPVGT----KKLTKSFGW---ETLDSFMQHDVQELCRVLLDNVEN 309
              +   L +     KP+      +++ + F +   E    F+Q+ V  + +  L+    
Sbjct: 160 QAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNK 219

Query: 310 KMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVA 369
             + T     + ++F G + S ++C      SD  + Y DI L IK  +++ ++   +V 
Sbjct: 220 LDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVK 279

Query: 370 VEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFP 428
            EQLDG+N Y   +   +  A K         VL L L RF          KI    ++P
Sbjct: 280 PEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYP 335

Query: 429 EQLPLDEFLQKTDPKDPANYILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFDDDVVSR 487
           E L +  ++ + +  +P  Y+L+AVLVH+G N H GHY  Y+    +G W + +D +VS 
Sbjct: 336 EYLDIRPYMSQPN-GEPIVYVLYAVLVHTGFNCHAGHYFCYIK-ASNGLWYQMNDSIVS- 392

Query: 488 CTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 520
                           D+       AY+L YIR
Sbjct: 393 --------------TSDIRSVLSQQAYVLFYIR 411


>gi|32313610 ubiquitin specific protease 18 [Homo sapiens]
          Length = 372

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 89/334 (26%), Positives = 144/334 (43%), Gaps = 28/334 (8%)

Query: 204 AWDSKKHTGYVGLKNQGATCYMNSLLQTLF----FTNQLRKAVYMMPTEGDDSSKSVPLA 259
           AWD     G VGL N G TC +NSL+Q       FT  L++    +P   D+  +SVP  
Sbjct: 47  AWDYPH--GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT--VPRGADEQRRSVPFQ 102

Query: 260 LQRVFYELQHS-DKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEG 318
           +  +  ++Q S  K V   +L        +  F+QHD  +L   L + +++++    +  
Sbjct: 103 MLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVE 162

Query: 319 TIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSI-----KGKKNIFESFVDYVAVEQL 373
            +  L+  ++   + C +    S R      + LS+     K  K + ++   +    +L
Sbjct: 163 RLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPREL 222

Query: 374 DGDNKYDAGEHGLQEAEKGVKFLT-LPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLP 432
              +K      G +   K V  LT LP  L + LMRF    +  Q  KI     FP+ L 
Sbjct: 223 SSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI--RNSQTRKICHSLYFPQSLD 280

Query: 433 LDEFLQK------TDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVS 486
             + L         + +    Y L AV+ H G    GHY VY+    DGKW  F+D  + 
Sbjct: 281 FSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNIC 340

Query: 487 RCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 520
             + E+ I+  YG    + +      AY+LVY++
Sbjct: 341 LVSWED-IQCTYG----NPNYHWQETAYLLVYMK 369


>gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo
           sapiens]
          Length = 530

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QQN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTAASITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo
           sapiens]
          Length = 530

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHPSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QQN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTAASITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1
           [Homo sapiens]
          Length = 530

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QQN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


>gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
           sapiens]
          Length = 530

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%)

Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266
           GL+N G TCY+N+ LQ L +T  L  A YM+  E   +          ++   + R  + 
Sbjct: 81  GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138

Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320
             H  +P  ++ L   F     E    F+   V  + +  L     V++  K T +   I
Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193

Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380
            ++F G   S I+C      SD  + Y DI L I+  +++ ++    V  E+L+G+N Y 
Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253

Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438
            G   LQ   A K +   T   VL L L RF          KI    ++PE L +  ++ 
Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308

Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497
           + +   P  Y+L+AVLVH+G   H GHY  Y+  + +G+W K DD  V+  +    +   
Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365

Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557
                          AY+L YI++S+     ++V+    P+ L     + +  + + +++
Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,656,900
Number of Sequences: 37866
Number of extensions: 2032473
Number of successful extensions: 7431
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 6910
Number of HSP's gapped (non-prelim): 359
length of query: 1102
length of database: 18,247,518
effective HSP length: 113
effective length of query: 989
effective length of database: 13,968,660
effective search space: 13815004740
effective search space used: 13815004740
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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