BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] (1102 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] 2272 0.0 gi|71774197 ubiquitin specific protease 47 [Homo sapiens] 184 5e-46 gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 164 4e-40 gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 151 4e-36 gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 149 1e-35 gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [... 124 6e-28 gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [... 124 6e-28 gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 123 8e-28 gi|149192845 ubiquitin specific protease 24 [Homo sapiens] 119 2e-26 gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens] 118 3e-26 gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 110 6e-24 gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 109 2e-23 gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 109 2e-23 gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ... 94 7e-19 gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo ... 94 9e-19 gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ... 94 9e-19 gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo ... 94 9e-19 gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo ... 94 9e-19 gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ... 93 1e-18 gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 93 1e-18 gi|32313610 ubiquitin specific protease 18 [Homo sapiens] 92 2e-18 gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ... 92 4e-18 gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo ... 92 4e-18 gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 91 5e-18 gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 91 5e-18 gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 91 5e-18 gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 91 5e-18 gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 91 5e-18 gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 91 5e-18 gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 91 5e-18 >gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] Length = 1102 Score = 2272 bits (5887), Expect = 0.0 Identities = 1102/1102 (100%), Positives = 1102/1102 (100%) Query: 1 MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME 60 MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME Sbjct: 1 MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME 60 Query: 61 DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ 120 DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ Sbjct: 61 DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ 120 Query: 121 CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE 180 CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE Sbjct: 121 CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE 180 Query: 181 KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK 240 KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK Sbjct: 181 KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK 240 Query: 241 AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC 300 AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC Sbjct: 241 AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC 300 Query: 301 RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI 360 RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI Sbjct: 301 RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI 360 Query: 361 FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK 420 FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK Sbjct: 361 FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK 420 Query: 421 INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF 480 INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF Sbjct: 421 INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF 480 Query: 481 DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL 540 DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL Sbjct: 481 DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL 540 Query: 541 VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS 600 VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS Sbjct: 541 VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS 600 Query: 601 SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI 660 SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI Sbjct: 601 SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI 660 Query: 661 FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM 720 FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM Sbjct: 661 FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM 720 Query: 721 CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL 780 CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL Sbjct: 721 CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL 780 Query: 781 PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF 840 PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF Sbjct: 781 PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF 840 Query: 841 KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN 900 KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN Sbjct: 841 KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN 900 Query: 901 SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE 960 SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE Sbjct: 901 SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE 960 Query: 961 CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV 1020 CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV Sbjct: 961 CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV 1020 Query: 1021 MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD 1080 MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD Sbjct: 1021 MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD 1080 Query: 1081 HFNKAPKRSRYTYLEKAIKIHN 1102 HFNKAPKRSRYTYLEKAIKIHN Sbjct: 1081 HFNKAPKRSRYTYLEKAIKIHN 1102 >gi|71774197 ubiquitin specific protease 47 [Homo sapiens] Length = 1287 Score = 184 bits (466), Expect = 5e-46 Identities = 107/249 (42%), Positives = 146/249 (58%), Gaps = 10/249 (4%) Query: 207 SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEG--DDSSKSVPLALQRVF 264 +K TGYVGL NQ TCY+NSLLQTLF T + R A+Y E +D S+P LQR+F Sbjct: 93 NKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLF 152 Query: 265 YELQHSDK-PVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKL 323 LQ S K + T +T+SFGW++ +++ QHDVQELCRV+ D +E K K T I +L Sbjct: 153 VLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINEL 212 Query: 324 FRGKMVSYIQCKEVDYRSDRREDYYDIQLSIK--GKKNIFESFVD----YVAVEQLDGDN 377 ++GK+ Y++C E Y R + Y DI L I+ G F S + ++ E LDG N Sbjct: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 Query: 378 KYDAGEHGLQ-EAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF 436 +Y + +A KG++FL P +L LQL RF +D T IK+NDR FPE+L + F Sbjct: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Query: 437 LQKTDPKDP 445 + D K P Sbjct: 333 IDVEDEKSP 341 Score = 70.5 bits (171), Expect = 8e-12 Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 22/168 (13%) Query: 443 KDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHD 502 K+ Y L +V+VHSG GGHY + D +W F+D VSR T+E+ I+ +GG Sbjct: 394 KNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQED-IKKTHGGSS 452 Query: 503 D-----DLSVRHCTNAYMLVY-----IRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEA 552 + TNAYML+Y R +K EV + P+ + +Q+E+ +E Sbjct: 453 GSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEV------DEYPEHIKNLVQKERELEE 506 Query: 553 QKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS 600 Q++++R+ ++++ FC H + E K++ K LK + Sbjct: 507 QEKRQREIERNTCKIKL-----FCLHPTKQVMMENKLEVHKDKTLKEA 549 >gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] Length = 1247 Score = 164 bits (415), Expect = 4e-40 Identities = 122/412 (29%), Positives = 201/412 (48%), Gaps = 48/412 (11%) Query: 208 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEG----------DDSSKSVP 257 ++ T G++NQG TCY+NSLLQTL FT + R+A++ + E D + +P Sbjct: 47 REFTNLSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDAKVRIIP 106 Query: 258 LALQRVFYELQHSDKPVG-TKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCV 316 L LQR+F +L D+ T LT SFGW + + QHDVQEL R+L +E + GT Sbjct: 107 LQLQRLFAQLLLLDQEAASTADLTDSFGWTSNEEMRQHDVQELNRILFSALETSLVGTSG 166 Query: 317 EGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVD-YVAVEQLDG 375 I +L+ G +V+ I CKE S+R+ED+ D+ +++K + ++ + YV E D Sbjct: 167 HDLIYRLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVKNVSGLEDALWNMYVEEEVFDC 226 Query: 376 DNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLD 434 DN Y G L +A K K LPP L + L+RF +D + K + FP ++ L Sbjct: 227 DNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLK 286 Query: 435 EFLQKTDPKD-PANYILHAVLVHSGDNHGGHYVVYLNPKGD-GKWCKFDDDVVSRCTKEE 492 F ++++ D Y L +V++H G +GGHY VY+ G W +F ++ + Sbjct: 287 PFCEQSELDDLEYIYDLFSVIIHKGGCYGGHYHVYIKDVDHLGNW-QFQEE-------KS 338 Query: 493 AIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVER--LQEEKRI 550 + N + + H + + E+ L V Q + Q+L+++ + K+ Sbjct: 339 KPDVNLKDLQSEEEIDHPLMILKAILLEENNLIPVDQ------LGQKLLKKIGISWNKKY 392 Query: 551 EAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSL 602 Q R+ L+ Q+ +++ D+ + ++LKNSSL Sbjct: 393 RKQHGPLRKFLQLHSQIFLLSSDE-----------------STVRLLKNSSL 427 >gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] Length = 1035 Score = 151 bits (381), Expect = 4e-36 Identities = 113/409 (27%), Positives = 199/409 (48%), Gaps = 47/409 (11%) Query: 206 DSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPT-------------EGDDS 252 + +K +VGL N GATCY+N+ LQ F +LR+A+Y+ P+ E D Sbjct: 81 ERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYE 140 Query: 253 SKSVPLALQRVFYELQHSDKP-VGTKKLTKSFGWETLDSFMQHDVQELCRV---LLDNVE 308 +++ LQ +F LQ+S++ + K+ G LD+ Q D QE ++ LL++ Sbjct: 141 PQTICEHLQYLFALLQNSNRRYIDPSGFVKALG---LDTGQQQDAQEFSKLFMSLLEDTL 197 Query: 309 NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYV 368 +K K V + + F G+ C + S +Y+++L+I+G K + + +++ Sbjct: 198 SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFL 257 Query: 369 AVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEF 427 E+L+GDN+Y Q A + ++ L+LP L+LQLMRF++D QT K+N F Sbjct: 258 KEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGF 317 Query: 428 PEQLPLDEFLQKTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVS 486 E L ++ +++ Y L AVL+H G + GHY+ ++ G+W KF+D+ + Sbjct: 318 SEILDMEPYVEHKG--GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIE 375 Query: 487 RCTKEE---AIEHNYGGHDDDLSVR-------HCT-NAYMLVYIRES--------KLSEV 527 + ++ IE + + + HC+ NAYMLVY ++ ++ Sbjct: 376 KMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAF 435 Query: 528 LQAVTDHD---IPQQLVERLQEEKR-IEAQKRKERQEAHLYMQVQIVAE 572 LQ + D D + +E + K+ ++ K K + LY ++ AE Sbjct: 436 LQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAE 484 >gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] Length = 485 Score = 149 bits (377), Expect = 1e-35 Identities = 111/404 (27%), Positives = 197/404 (48%), Gaps = 47/404 (11%) Query: 206 DSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPT-------------EGDDS 252 + +K +VGL N GATCY+N+ LQ F +LR+A+Y+ P+ E D Sbjct: 81 ERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYE 140 Query: 253 SKSVPLALQRVFYELQHSDKP-VGTKKLTKSFGWETLDSFMQHDVQELCRV---LLDNVE 308 +++ LQ +F LQ+S++ + K+ G LD+ Q D QE ++ LL++ Sbjct: 141 PQTICEHLQYLFALLQNSNRRYIDPSGFVKALG---LDTGQQQDAQEFSKLFMSLLEDTL 197 Query: 309 NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYV 368 +K K V + + F G+ C + S +Y+++L+I+G K + + +++ Sbjct: 198 SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFL 257 Query: 369 AVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEF 427 E+L+GDN+Y Q A + ++ L+LP L+LQLMRF++D QT K+N F Sbjct: 258 KEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGF 317 Query: 428 PEQLPLDEFLQKTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVS 486 E L ++ +++ Y L AVL+H G + GHY+ ++ G+W KF+D+ + Sbjct: 318 SEILDMEPYVEHKG--GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIE 375 Query: 487 RCTKEE---AIEHNYGGHDDDLSVR-------HCT-NAYMLVYIRES--------KLSEV 527 + ++ IE + + + HC+ NAYMLVY ++ ++ Sbjct: 376 KMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAF 435 Query: 528 LQAVTDHD---IPQQLVERLQEEKR-IEAQKRKERQEAHLYMQV 567 LQ + D D + +E + K+ ++ K K + LY ++ Sbjct: 436 LQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRL 479 >gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo sapiens] Length = 2554 Score = 124 bits (310), Expect = 6e-28 Identities = 115/440 (26%), Positives = 179/440 (40%), Gaps = 98/440 (22%) Query: 212 GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY------------MMPTEGDDSSKSVPLA 259 G+VGLKN GATCYMNS++Q L+ +R + M E D+ +V Sbjct: 1555 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1614 Query: 260 LQRVFYELQHSDKPVGTKK-------------LTKSFG---------------------W 285 Y Q DKP +K L FG W Sbjct: 1615 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLW 1674 Query: 286 -ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRR 344 E ++ QHD E L+D+++ +K + K+ G C+ +R + Sbjct: 1675 GEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECE 1734 Query: 345 EDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLH 403 E + + + I+ +N+ +S YV + L+G N Y + + + K + LPPVL Sbjct: 1735 ESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLA 1794 Query: 404 LQLMRFMYDPQTDQNIKINDRFEFPEQL-------------------PLDEFLQKTDPKD 444 +QL RF YD + + IK ND FEFP +L P + +Q+++ + Sbjct: 1795 IQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSE 1854 Query: 445 -----PANYILHAVLVHSGDNHGGHYVVYLNPK--GDG---KWCKFDDDVVSRC------ 488 Y L VLVHSG GGHY Y+ + GDG +W KFDD V+ C Sbjct: 1855 SETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDE 1914 Query: 489 -TKEEAIEHNYGGHDDDLSVRHCT--------NAYMLVYIRESKL---SEVLQAVTDHDI 536 K + Y G D ++ + NAY+L Y R + E+++ +++ I Sbjct: 1915 EMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAI 1974 Query: 537 ---PQQLVERLQEEKRIEAQ 553 P Q++ E+ + Q Sbjct: 1975 TTRPHQIIMPSAIERSVRKQ 1994 >gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo sapiens] Length = 2570 Score = 124 bits (310), Expect = 6e-28 Identities = 115/440 (26%), Positives = 179/440 (40%), Gaps = 98/440 (22%) Query: 212 GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY------------MMPTEGDDSSKSVPLA 259 G+VGLKN GATCYMNS++Q L+ +R + M E D+ +V Sbjct: 1555 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1614 Query: 260 LQRVFYELQHSDKPVGTKK-------------LTKSFG---------------------W 285 Y Q DKP +K L FG W Sbjct: 1615 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLW 1674 Query: 286 -ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRR 344 E ++ QHD E L+D+++ +K + K+ G C+ +R + Sbjct: 1675 GEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECE 1734 Query: 345 EDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLH 403 E + + + I+ +N+ +S YV + L+G N Y + + + K + LPPVL Sbjct: 1735 ESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLA 1794 Query: 404 LQLMRFMYDPQTDQNIKINDRFEFPEQL-------------------PLDEFLQKTDPKD 444 +QL RF YD + + IK ND FEFP +L P + +Q+++ + Sbjct: 1795 IQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSE 1854 Query: 445 -----PANYILHAVLVHSGDNHGGHYVVYLNPK--GDG---KWCKFDDDVVSRC------ 488 Y L VLVHSG GGHY Y+ + GDG +W KFDD V+ C Sbjct: 1855 SETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDE 1914 Query: 489 -TKEEAIEHNYGGHDDDLSVRHCT--------NAYMLVYIRESKL---SEVLQAVTDHDI 536 K + Y G D ++ + NAY+L Y R + E+++ +++ I Sbjct: 1915 EMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTIDQDDELIRYISELAI 1974 Query: 537 ---PQQLVERLQEEKRIEAQ 553 P Q++ E+ + Q Sbjct: 1975 TTRPHQIIMPSAIERSVRKQ 1994 >gi|110347427 ubiquitin specific protease 34 [Homo sapiens] Length = 3546 Score = 123 bits (309), Expect = 8e-28 Identities = 103/372 (27%), Positives = 163/372 (43%), Gaps = 50/372 (13%) Query: 195 VQADAPHGVAWDSKKHTG------YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTE 248 +Q+ AP+ WD H +VGL N GATCY+ S +Q L+ + R+AV+ Sbjct: 1871 MQSHAPY--KWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYS 1928 Query: 249 GDDSSKSVPLALQRVFYELQHSD-KPVGTKKLTKSFGW--ETLDSFMQHDVQELCRVLLD 305 D K+ L LQ++F L S+ K + K++ + L++ Q D+ E L+ Sbjct: 1929 EDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLIT 1988 Query: 306 NVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFV 365 +E ++ T+ LF G + + + + ++ S E++Y ++ + KNI+ES Sbjct: 1989 KIEEMSPE--LKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLD 2046 Query: 366 DYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDR 424 + + L+GDN Y G + AEK F LP +L MR+ ++ T K+N Sbjct: 2047 EVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTH 2106 Query: 425 FEFPEQLPL-----DEFLQKTDPK-------------DPANYILHAVLVHSGDNHGGHYV 466 F FP +L + D + K++ K + Y L V VH+G GGHY Sbjct: 2107 FSFPLRLDMTPYTEDFLMGKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYY 2166 Query: 467 VYL----NPKG--DGKWCKFDD---------DVVSRCTKEEAIEHNYGGHDD---DLSVR 508 ++ NP + KW F+D + S C E Y D D S Sbjct: 2167 SFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFE 2226 Query: 509 HCTNAYMLVYIR 520 +AYML Y R Sbjct: 2227 KTHSAYMLFYKR 2238 >gi|149192845 ubiquitin specific protease 24 [Homo sapiens] Length = 2460 Score = 119 bits (297), Expect = 2e-26 Identities = 101/366 (27%), Positives = 162/366 (44%), Gaps = 52/366 (14%) Query: 206 DSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFY 265 DS+ +G+VGL+N GATCYMN++ Q L+ L +++ + + D+ SV +Q +F Sbjct: 1521 DSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFG 1580 Query: 266 ELQHSD----KPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIP 321 L S P K+ K + E L Q D E L+D ++ +K + Sbjct: 1581 HLMESKLQYYVPENFWKIFKMWNKE-LYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFK 1639 Query: 322 KLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDA 381 F+G CK+ +R +R E + + L + +++ S +V E L+G N Y Sbjct: 1640 NTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYC 1699 Query: 382 GEHGLQEAEKGVK---FLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF-- 436 + +E VK +LP VL + LMRF +D ++ ++IK +++ FP L ++ + Sbjct: 1700 EK--CKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTV 1757 Query: 437 --LQKTDPKDPA-----------------------NYILHAVLVHSGDNHGGHYVVYLNP 471 + + D NY L V+VHSG H GHY ++ Sbjct: 1758 SGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKD 1817 Query: 472 K---GDGKWCKFDDDVVSRC-TKEEAIEHNYGGHDDDLSV-----------RHCTNAYML 516 + G GKW KF+D V+ +E +E+ G + V R NAYML Sbjct: 1818 RRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYML 1877 Query: 517 VYIRES 522 Y R S Sbjct: 1878 FYQRVS 1883 >gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens] Length = 2555 Score = 118 bits (296), Expect = 3e-26 Identities = 114/442 (25%), Positives = 178/442 (40%), Gaps = 97/442 (21%) Query: 212 GYVGLKNQGATCYMNSLLQTLFFTNQLRKAVY------------MMPTEGDDSSKSVPLA 259 G+VGLKN GATCYMNS++Q L+ +R ++ M E DS +V Sbjct: 1557 GFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPR 1616 Query: 260 LQRVFYELQHSDKPVGTKK-------------LTKSFG---------------------W 285 Y Q DKP +K L FG W Sbjct: 1617 DDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLW 1676 Query: 286 -ETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRR 344 E ++ QHD E L+D+++ +K + K+ G C+ +R + Sbjct: 1677 GEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECE 1736 Query: 345 EDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQ-EAEKGVKFLTLPPVLH 403 E + + + I+ +N+ +S Y+ + L+G N Y + + + K + LP VL Sbjct: 1737 ESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLA 1796 Query: 404 LQLMRFMYDPQTDQNIKINDRFEFPEQLPL-------------------DEFLQKTDPKD 444 +QL RF YD + + IK ND FEFP +L + +E +++ + D Sbjct: 1797 IQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSD 1856 Query: 445 -----PANYILHAVLVHSGDNHGGHYVVYL---NPKGD--GKWCKFDDDVVSRC------ 488 Y L VLVHSG GGHY Y+ N K D W KFDD V+ C Sbjct: 1857 NETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDE 1916 Query: 489 -TKEEAIEHNYGGHDDDLSVRHCT--------NAYMLVYIRESKL---SEVLQAVTDHDI 536 K + Y G D ++ + NAY+L Y + + E+++ +++ I Sbjct: 1917 EMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTI 1976 Query: 537 --PQQLVERLQEEKRIEAQKRK 556 P Q++ E+ + Q K Sbjct: 1977 ARPHQIIMSPAIERSVRKQNVK 1998 >gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] Length = 370 Score = 110 bits (276), Expect = 6e-24 Identities = 98/337 (29%), Positives = 152/337 (45%), Gaps = 39/337 (11%) Query: 213 YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDK 272 Y GL N G TCY NS+LQ L+F R+ V ++ +S+ L +F+ + K Sbjct: 38 YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQ-PRKKESLLTCLADLFHSIATQKK 96 Query: 273 PVGT---KKLTKSFGWET--LDSFMQHDVQELCRVLLD---------------------- 305 VG KK E D++MQ D E LL+ Sbjct: 97 KVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG 156 Query: 306 NVENKMKGTCVEGT-IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESF 364 N++N+ + + T + ++F+G + + +C + S + ED+ D+ + ++ +I Sbjct: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCL 216 Query: 365 VDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKIND 423 + E L + KY E QEA K +K LP +L L L RF Y Q + K++ Sbjct: 217 RGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSY 276 Query: 424 RFEFPEQLPLDEFLQKTDPKDPAN-YILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFD 481 R FP +L L F D +P Y L AV+VH G + GHY+ + K W FD Sbjct: 277 RVVFPLELRL--FNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIV--KSHDFWLLFD 332 Query: 482 DDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518 DD+V + +AIE Y G D+S ++ + Y+L Y Sbjct: 333 DDIVEK-IDAQAIEEFY-GLTSDIS-KNSESGYILFY 366 >gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sapiens] Length = 359 Score = 109 bits (272), Expect = 2e-23 Identities = 96/337 (28%), Positives = 150/337 (44%), Gaps = 39/337 (11%) Query: 213 YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDK 272 Y GL N G TCY NS+LQ L+F R+ V + +++ L +F+ + K Sbjct: 27 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ-QKKKENLLTCLADLFHSIATQKK 85 Query: 273 PVGT---KKLTKSFGWET--LDSFMQHDVQELCRVLLDNV---------ENKMKGTCVEG 318 VG KK E D++MQ D E LL+ + + K G G Sbjct: 86 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 145 Query: 319 T--------------IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESF 364 + ++F+G + + +C + S + ED+ D+ + ++ +I Sbjct: 146 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCL 205 Query: 365 VDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKIND 423 D+ E L + KY QEA+K ++ LP +L L L RF Y Q + K++ Sbjct: 206 RDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSY 265 Query: 424 RFEFPEQLPLDEFLQKTDPKD-PANYILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFD 481 R FP +L L F +D + Y L AV+VH G + GHY+ + K G W FD Sbjct: 266 RVVFPLELRL--FNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIV--KSHGFWLLFD 321 Query: 482 DDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518 DD+V + +AIE Y G D+S ++ + Y+L Y Sbjct: 322 DDIVEK-IDAQAIEEFY-GLTSDIS-KNSESGYILFY 355 >gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapiens] Length = 366 Score = 109 bits (272), Expect = 2e-23 Identities = 96/337 (28%), Positives = 150/337 (44%), Gaps = 39/337 (11%) Query: 213 YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDK 272 Y GL N G TCY NS+LQ L+F R+ V + +++ L +F+ + K Sbjct: 34 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ-QKKKENLLTCLADLFHSIATQKK 92 Query: 273 PVGT---KKLTKSFGWET--LDSFMQHDVQELCRVLLDNV---------ENKMKGTCVEG 318 VG KK E D++MQ D E LL+ + + K G G Sbjct: 93 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 152 Query: 319 T--------------IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESF 364 + ++F+G + + +C + S + ED+ D+ + ++ +I Sbjct: 153 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCL 212 Query: 365 VDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKIND 423 D+ E L + KY QEA+K ++ LP +L L L RF Y Q + K++ Sbjct: 213 RDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSY 272 Query: 424 RFEFPEQLPLDEFLQKTDPKD-PANYILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFD 481 R FP +L L F +D + Y L AV+VH G + GHY+ + K G W FD Sbjct: 273 RVVFPLELRL--FNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIV--KSHGFWLLFD 328 Query: 482 DDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518 DD+V + +AIE Y G D+S ++ + Y+L Y Sbjct: 329 DDIVEK-IDAQAIEEFY-GLTSDIS-KNSESGYILFY 362 >gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo sapiens] Length = 559 Score = 94.0 bits (232), Expect = 7e-19 Identities = 95/360 (26%), Positives = 161/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI+ ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIDKNVQYPECLDMKLYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 +T+ P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QTN-SGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo sapiens] Length = 530 Score = 93.6 bits (231), Expect = 9e-19 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + LT VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKMLTLLTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo sapiens] Length = 530 Score = 93.6 bits (231), Expect = 9e-19 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 +T+ P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QTN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo sapiens] Length = 530 Score = 93.6 bits (231), Expect = 9e-19 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + LT VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKMLTLLTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo sapiens] Length = 530 Score = 93.6 bits (231), Expect = 9e-19 Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 +T+ P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QTN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo sapiens] Length = 530 Score = 93.2 bits (230), Expect = 1e-18 Identities = 95/343 (27%), Positives = 153/343 (44%), Gaps = 46/343 (13%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 +T+ P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QTN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL 540 AY+L YI++S+ ++V+ P+ L Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRAL 394 >gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] Length = 1316 Score = 93.2 bits (230), Expect = 1e-18 Identities = 88/333 (26%), Positives = 144/333 (43%), Gaps = 41/333 (12%) Query: 205 WDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQ--- 261 W G GL+N G TC+ N+ LQ L +T L A YM+ E + + + Sbjct: 103 WQQTHRVG-AGLQNLGNTCFANAALQCLTYTPPL--ANYMLSHEHSKTCHAEGFCMMCTM 159 Query: 262 --RVFYELQHSD---KPVGT----KKLTKSFGW---ETLDSFMQHDVQELCRVLLDNVEN 309 + L + KP+ +++ + F + E F+Q+ V + + L+ Sbjct: 160 QAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNK 219 Query: 310 KMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVA 369 + T + ++F G + S ++C SD + Y DI L IK +++ ++ +V Sbjct: 220 LDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVK 279 Query: 370 VEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFP 428 EQLDG+N Y + + A K VL L L RF KI ++P Sbjct: 280 PEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYP 335 Query: 429 EQLPLDEFLQKTDPKDPANYILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFDDDVVSR 487 E L + ++ + + +P Y+L+AVLVH+G N H GHY Y+ +G W + +D +VS Sbjct: 336 EYLDIRPYMSQPN-GEPIVYVLYAVLVHTGFNCHAGHYFCYIK-ASNGLWYQMNDSIVS- 392 Query: 488 CTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 520 D+ AY+L YIR Sbjct: 393 --------------TSDIRSVLSQQAYVLFYIR 411 >gi|32313610 ubiquitin specific protease 18 [Homo sapiens] Length = 372 Score = 92.4 bits (228), Expect = 2e-18 Identities = 89/334 (26%), Positives = 144/334 (43%), Gaps = 28/334 (8%) Query: 204 AWDSKKHTGYVGLKNQGATCYMNSLLQTLF----FTNQLRKAVYMMPTEGDDSSKSVPLA 259 AWD G VGL N G TC +NSL+Q FT L++ +P D+ +SVP Sbjct: 47 AWDYPH--GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT--VPRGADEQRRSVPFQ 102 Query: 260 LQRVFYELQHS-DKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEG 318 + + ++Q S K V +L + F+QHD +L L + +++++ + Sbjct: 103 MLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVE 162 Query: 319 TIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSI-----KGKKNIFESFVDYVAVEQL 373 + L+ ++ + C + S R + LS+ K K + ++ + +L Sbjct: 163 RLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPREL 222 Query: 374 DGDNKYDAGEHGLQEAEKGVKFLT-LPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLP 432 +K G + K V LT LP L + LMRF + Q KI FP+ L Sbjct: 223 SSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI--RNSQTRKICHSLYFPQSLD 280 Query: 433 LDEFLQK------TDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVS 486 + L + + Y L AV+ H G GHY VY+ DGKW F+D + Sbjct: 281 FSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNIC 340 Query: 487 RCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 520 + E+ I+ YG + + AY+LVY++ Sbjct: 341 LVSWED-IQCTYG----NPNYHWQETAYLLVYMK 369 >gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo sapiens] Length = 530 Score = 91.7 bits (226), Expect = 4e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QQN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTAASITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo sapiens] Length = 530 Score = 91.7 bits (226), Expect = 4e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHPSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QQN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTAASITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 [Homo sapiens] Length = 530 Score = 91.3 bits (225), Expect = 5e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QQN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo sapiens] Length = 530 Score = 91.3 bits (225), Expect = 5e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo sapiens] Length = 530 Score = 91.3 bits (225), Expect = 5e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo sapiens] Length = 530 Score = 91.3 bits (225), Expect = 5e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo sapiens] Length = 530 Score = 91.3 bits (225), Expect = 5e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Homo sapiens] Length = 530 Score = 91.3 bits (225), Expect = 5e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 >gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Homo sapiens] Length = 530 Score = 91.3 bits (225), Expect = 5e-18 Identities = 94/360 (26%), Positives = 159/360 (44%), Gaps = 46/360 (12%) Query: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSK--------SVPLALQRVFYE 266 GL+N G TCY+N+ LQ L +T L A YM+ E + ++ + R + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPL--ANYMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138 Query: 267 LQHSDKPVGTKKLTKSFG---WETLDSFMQHDVQELCRVLLDN---VENKMKGTCVEGTI 320 H +P ++ L F E F+ V + + L V++ K T + I Sbjct: 139 PGHVIQP--SQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---I 193 Query: 321 PKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYD 380 ++F G S I+C SD + Y DI L I+ +++ ++ V E+L+G+N Y Sbjct: 194 HQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYH 253 Query: 381 AGEHGLQE--AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 438 G LQ A K + T VL L L RF KI ++PE L + ++ Sbjct: 254 CGV-CLQRAPASKTLTLHTSAKVLILVLKRF----SDVTGNKIAKNVQYPECLDMQPYMS 308 Query: 439 KTDPKDPANYILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHN 497 + + P Y+L+AVLVH+G H GHY Y+ + +G+W K DD V+ + + Sbjct: 309 QPN-TGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQ-EGQWYKMDDAEVTASSITSVLSQ- 365 Query: 498 YGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKE 557 AY+L YI++S+ ++V+ P+ L + + + + +++ Sbjct: 366 --------------QAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRD 411 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,656,900 Number of Sequences: 37866 Number of extensions: 2032473 Number of successful extensions: 7431 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 105 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 6910 Number of HSP's gapped (non-prelim): 359 length of query: 1102 length of database: 18,247,518 effective HSP length: 113 effective length of query: 989 effective length of database: 13,968,660 effective search space: 13815004740 effective search space used: 13815004740 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.