Search of human proteins with 11024682

Search of human proteins with 11024682

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11024682 insulin-like growth factor 1 isoform 4
preproprotein [Homo sapiens]
         (153 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein...   320   3e-88
gi|163659903 insulin-like growth factor 1 isoform 3 preproprotei...   282   9e-77
gi|163659899 insulin-like growth factor 1 isoform 1 preproprotei...   282   9e-77
gi|163659901 insulin-like growth factor 1 isoform 2 preproprotei...   275   1e-74
gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Hom...    94   6e-20
gi|108796063 insulin-like growth factor 2 isoform 1 precursor [H...    94   6e-20
gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens]     94   6e-20
gi|4557671 proinsulin precursor [Homo sapiens]                         49   1e-06
gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]      37   0.007
gi|38454322 adhesion molecule with Ig-like domain 3 [Homo sapiens]     29   1.4  
gi|5902052 relaxin 1 preproprotein [Homo sapiens]                      29   1.8  
gi|5016090 nuclear receptor subfamily 0, group B, member 1 [Homo...    28   2.3  
gi|53729363 leucine rich repeat and sterile alpha motif containi...    28   3.1  
gi|53729361 leucine rich repeat and sterile alpha motif containi...    28   3.1  
gi|53729359 leucine rich repeat and sterile alpha motif containi...    28   3.1  
gi|4508045 zona pellucida glycoprotein 2 preproprotein [Homo sap...    28   3.1  
gi|46048171 MAS-related GPR, member X3 [Homo sapiens]                  27   8.9  

>gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein
           [Homo sapiens]
          Length = 153

 Score =  320 bits (820), Expect = 3e-88
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 1   MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 60
           MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
Sbjct: 1   MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 60

Query: 61  ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 120
           ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
Sbjct: 61  ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 120

Query: 121 VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM 153
           VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM
Sbjct: 121 VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM 153


>gi|163659903 insulin-like growth factor 1 isoform 3 preproprotein
           [Homo sapiens]
          Length = 195

 Score =  282 bits (721), Expect = 9e-77
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 60
           MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
Sbjct: 1   MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 60

Query: 61  ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 120
           ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
Sbjct: 61  ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 120

Query: 121 VRAQRHTDMPKTQK 134
           VRAQRHTDMPKTQK
Sbjct: 121 VRAQRHTDMPKTQK 134


>gi|163659899 insulin-like growth factor 1 isoform 1 preproprotein
           [Homo sapiens]
          Length = 158

 Score =  282 bits (721), Expect = 9e-77
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 60
           MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
Sbjct: 1   MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 60

Query: 61  ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 120
           ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
Sbjct: 61  ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 120

Query: 121 VRAQRHTDMPKTQK 134
           VRAQRHTDMPKTQK
Sbjct: 121 VRAQRHTDMPKTQK 134


>gi|163659901 insulin-like growth factor 1 isoform 2 preproprotein
           [Homo sapiens]
          Length = 137

 Score =  275 bits (702), Expect = 1e-74
 Identities = 132/132 (100%), Positives = 132/132 (100%)

Query: 22  VKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGS 81
           VKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGS
Sbjct: 6   VKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGS 65

Query: 82  SSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKTQKEVHLKNA 141
           SSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKTQKEVHLKNA
Sbjct: 66  SSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKTQKEVHLKNA 125

Query: 142 SRGSAGNKNYRM 153
           SRGSAGNKNYRM
Sbjct: 126 SRGSAGNKNYRM 137


>gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Homo
           sapiens]
          Length = 180

 Score = 93.6 bits (231), Expect = 6e-20
 Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 37  LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
           L LLTF + A+         ETLCG ELVD LQFVCGDRGFYF++P    S   R    G
Sbjct: 10  LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65

Query: 91  IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
           IV+ECCFRSCDL  LE YCA   PAKS R V
Sbjct: 66  IVEECCFRSCDLALLETYCA--TPAKSERDV 94


>gi|108796063 insulin-like growth factor 2 isoform 1 precursor [Homo
           sapiens]
          Length = 180

 Score = 93.6 bits (231), Expect = 6e-20
 Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 37  LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
           L LLTF + A+         ETLCG ELVD LQFVCGDRGFYF++P    S   R    G
Sbjct: 10  LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 65

Query: 91  IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
           IV+ECCFRSCDL  LE YCA   PAKS R V
Sbjct: 66  IVEECCFRSCDLALLETYCA--TPAKSERDV 94


>gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens]
          Length = 236

 Score = 93.6 bits (231), Expect = 6e-20
 Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)

Query: 37  LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
           L LLTF + A+         ETLCG ELVD LQFVCGDRGFYF++P    S   R    G
Sbjct: 66  LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 121

Query: 91  IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
           IV+ECCFRSCDL  LE YCA   PAKS R V
Sbjct: 122 IVEECCFRSCDLALLETYCA--TPAKSERDV 150


>gi|4557671 proinsulin precursor [Homo sapiens]
          Length = 110

 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 23/80 (28%)

Query: 53  LCGAELVDALQFVCGDRGFYFNKPT----------------GYGSSSRR-------APQT 89
           LCG+ LV+AL  VCG+RGF++   T                G G+ S +         + 
Sbjct: 30  LCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKR 89

Query: 90  GIVDECCFRSCDLRRLEMYC 109
           GIV++CC   C L +LE YC
Sbjct: 90  GIVEQCCTSICSLYQLENYC 109


>gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]
          Length = 200

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 14/25 (56%), Positives = 19/25 (76%)

Query: 53 LCGAELVDALQFVCGDRGFYFNKPT 77
          LCG+ LV+AL  VCG+RGF++   T
Sbjct: 30 LCGSHLVEALYLVCGERGFFYTPKT 54


>gi|38454322 adhesion molecule with Ig-like domain 3 [Homo sapiens]
          Length = 504

 Score = 29.3 bits (64), Expect = 1.4
 Identities = 14/43 (32%), Positives = 20/43 (46%)

Query: 95  CCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKTQKEVH 137
           CC R+C  RR     +PL+   +  SV +    D P  +  VH
Sbjct: 409 CCRRACRCRRWPQTPSPLQELSAQSSVLSTTPPDAPSRKASVH 451


>gi|5902052 relaxin 1 preproprotein [Homo sapiens]
          Length = 185

 Score = 28.9 bits (63), Expect = 1.8
 Identities = 10/29 (34%), Positives = 14/29 (48%)

Query: 81  SSSRRAPQTGIVDECCFRSCDLRRLEMYC 109
           S  +R P   + ++CC   C  R L  YC
Sbjct: 157 SQKKRRPYVALFEKCCLIGCTKRSLAKYC 185


>gi|5016090 nuclear receptor subfamily 0, group B, member 1 [Homo
           sapiens]
          Length = 470

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 16/103 (15%)

Query: 11  LFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFVCGDRG 70
           L++CCFC     + H    S + Y  L     T  A A PE   G            DR 
Sbjct: 129 LYRCCFCG----EDHPRQGS-ILYSLLTSSKQTHVAPAAPEARPGG--------AWWDRS 175

Query: 71  FYFNKPTGYGSSSRRAPQTGIVDECCFRSCD--LRRLEMYCAP 111
           ++  +P G   +      T ++  CCF   D   +   +YC P
Sbjct: 176 YFAQRPGG-KEALPGGRATALLYRCCFCGEDHPQQGSTLYCVP 217


>gi|53729363 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 28.1 bits (61), Expect = 3.1
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 50  PETLCGAELVDALQFVCGDRGFYFNKPTGY 79
           P  +CGA     LQF+C + G  +  P+ Y
Sbjct: 189 PREVCGAGTAAILQFLCKESGLEYYPPSQY 218


>gi|53729361 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 28.1 bits (61), Expect = 3.1
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 50  PETLCGAELVDALQFVCGDRGFYFNKPTGY 79
           P  +CGA     LQF+C + G  +  P+ Y
Sbjct: 189 PREVCGAGTAAILQFLCKESGLEYYPPSQY 218


>gi|53729359 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 28.1 bits (61), Expect = 3.1
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 50  PETLCGAELVDALQFVCGDRGFYFNKPTGY 79
           P  +CGA     LQF+C + G  +  P+ Y
Sbjct: 189 PREVCGAGTAAILQFLCKESGLEYYPPSQY 218


>gi|4508045 zona pellucida glycoprotein 2 preproprotein [Homo
           sapiens]
          Length = 745

 Score = 28.1 bits (61), Expect = 3.1
 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 5/57 (8%)

Query: 20  LKVKMHTMSSSHLFYLALCLLTF-----TSSATAGPETLCGAELVDALQFVCGDRGF 71
           LK K+      H FYLA   LTF     T S    PE LC + +      +C   GF
Sbjct: 321 LKTKLSEKCLLHQFYLASLKLTFLLRPETVSMVIYPECLCESPVSIVTGELCTQDGF 377


>gi|46048171 MAS-related GPR, member X3 [Homo sapiens]
          Length = 322

 Score = 26.6 bits (57), Expect = 8.9
 Identities = 17/64 (26%), Positives = 28/64 (43%), Gaps = 6/64 (9%)

Query: 6   SLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFV 65
           SL   + +  FCDFL     ++      ++ +  L F          LCG+ LV  ++ +
Sbjct: 150 SLLRSILEWMFCDFLFSGADSVWCETSDFITIAWLVFLCVV------LCGSSLVLLVRIL 203

Query: 66  CGDR 69
           CG R
Sbjct: 204 CGSR 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.134    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,974,622
Number of Sequences: 37866
Number of extensions: 245452
Number of successful extensions: 723
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 703
Number of HSP's gapped (non-prelim): 20
length of query: 153
length of database: 18,247,518
effective HSP length: 93
effective length of query: 60
effective length of database: 14,725,980
effective search space: 883558800
effective search space used: 883558800
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.