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Search of human proteins with 110224452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
(1091 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 2176 0.0
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 2176 0.0
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 2176 0.0
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 2176 0.0
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 2138 0.0
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 2118 0.0
gi|4827006 solute carrier family 12, member 4 isoform a [Homo sa... 1669 0.0
gi|225579065 solute carrier family 12, member 4 isoform d [Homo ... 1665 0.0
gi|225579067 solute carrier family 12, member 4 isoform e [Homo ... 1664 0.0
gi|225579061 solute carrier family 12, member 4 isoform b [Homo ... 1652 0.0
gi|225579063 solute carrier family 12, member 4 isoform c [Homo ... 1641 0.0
gi|198041678 solute carrier family 12 (potassium-chloride transp... 1555 0.0
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 1555 0.0
gi|123701900 solute carrier family 12 (potassium/chloride transp... 1512 0.0
gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo ... 239 1e-62
gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo ... 236 1e-61
gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo ... 236 1e-61
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 223 1e-57
gi|134254459 sodium potassium chloride cotransporter 2 [Homo sap... 211 2e-54
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 195 2e-49
gi|38569457 solute carrier family 12, member 8 [Homo sapiens] 104 4e-22
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 47 1e-04
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 46 2e-04
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 40 0.009
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 37 0.078
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 36 0.17
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 36 0.17
gi|181337167 solute carrier family 7 (cationic amino acid transp... 36 0.17
gi|114326550 solute carrier family 7 (cationic amino acid transp... 35 0.30
gi|114326544 solute carrier family 7 (cationic amino acid transp... 35 0.30
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 2176 bits (5639), Expect = 0.0
Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)
Query: 1 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 60
MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN
Sbjct: 51 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 110
Query: 61 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 120
SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP
Sbjct: 111 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 170
Query: 121 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 180
TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS
Sbjct: 171 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 230
Query: 181 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 240
AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA
Sbjct: 231 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 290
Query: 241 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 300
AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY
Sbjct: 291 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 350
Query: 301 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 360
AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT
Sbjct: 351 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 410
Query: 361 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 420
CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV
Sbjct: 411 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 470
Query: 421 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 480
DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG
Sbjct: 471 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 530
Query: 481 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 540
ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA
Sbjct: 531 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 590
Query: 541 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL
Sbjct: 591 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 650
Query: 601 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 660
ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY
Sbjct: 651 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 710
Query: 661 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 720
QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF
Sbjct: 711 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 770
Query: 721 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 780
ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI
Sbjct: 771 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 830
Query: 781 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 840
SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF
Sbjct: 831 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 890
Query: 841 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 900
PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD
Sbjct: 891 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 950
Query: 901 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 960
LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK
Sbjct: 951 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 1010
Query: 961 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1020
DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS
Sbjct: 1011 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1070
Query: 1021 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1080
NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR
Sbjct: 1071 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1130
Query: 1081 GGGSEVITIYS 1091
GGGSEVITIYS
Sbjct: 1131 GGGSEVITIYS 1141
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 2176 bits (5639), Expect = 0.0
Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)
Query: 1 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 60
MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN
Sbjct: 1 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 60
Query: 61 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 120
SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP
Sbjct: 61 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 120
Query: 121 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 180
TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS
Sbjct: 121 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 180
Query: 181 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 240
AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA
Sbjct: 181 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 240
Query: 241 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 300
AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY
Sbjct: 241 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 300
Query: 301 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 360
AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT
Sbjct: 301 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 360
Query: 361 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 420
CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV
Sbjct: 361 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 420
Query: 421 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 480
DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG
Sbjct: 421 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 480
Query: 481 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 540
ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA
Sbjct: 481 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 540
Query: 541 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL
Sbjct: 541 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
Query: 601 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 660
ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY
Sbjct: 601 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 660
Query: 661 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 720
QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF
Sbjct: 661 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 720
Query: 721 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 780
ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI
Sbjct: 721 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 780
Query: 781 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 840
SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF
Sbjct: 781 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 840
Query: 841 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 900
PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD
Sbjct: 841 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 900
Query: 901 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 960
LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK
Sbjct: 901 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 960
Query: 961 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1020
DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS
Sbjct: 961 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1020
Query: 1021 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1080
NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR
Sbjct: 1021 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1080
Query: 1081 GGGSEVITIYS 1091
GGGSEVITIYS
Sbjct: 1081 GGGSEVITIYS 1091
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 2176 bits (5639), Expect = 0.0
Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)
Query: 1 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 60
MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN
Sbjct: 1 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 60
Query: 61 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 120
SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP
Sbjct: 61 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 120
Query: 121 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 180
TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS
Sbjct: 121 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 180
Query: 181 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 240
AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA
Sbjct: 181 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 240
Query: 241 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 300
AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY
Sbjct: 241 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 300
Query: 301 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 360
AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT
Sbjct: 301 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 360
Query: 361 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 420
CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV
Sbjct: 361 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 420
Query: 421 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 480
DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG
Sbjct: 421 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 480
Query: 481 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 540
ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA
Sbjct: 481 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 540
Query: 541 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL
Sbjct: 541 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
Query: 601 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 660
ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY
Sbjct: 601 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 660
Query: 661 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 720
QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF
Sbjct: 661 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 720
Query: 721 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 780
ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI
Sbjct: 721 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 780
Query: 781 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 840
SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF
Sbjct: 781 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 840
Query: 841 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 900
PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD
Sbjct: 841 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 900
Query: 901 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 960
LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK
Sbjct: 901 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 960
Query: 961 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1020
DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS
Sbjct: 961 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1020
Query: 1021 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1080
NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR
Sbjct: 1021 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1080
Query: 1081 GGGSEVITIYS 1091
GGGSEVITIYS
Sbjct: 1081 GGGSEVITIYS 1091
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 2176 bits (5639), Expect = 0.0
Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)
Query: 1 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 60
MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN
Sbjct: 60 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 119
Query: 61 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 120
SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP
Sbjct: 120 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 179
Query: 121 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 180
TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS
Sbjct: 180 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 239
Query: 181 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 240
AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA
Sbjct: 240 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 299
Query: 241 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 300
AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY
Sbjct: 300 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 359
Query: 301 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 360
AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT
Sbjct: 360 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 419
Query: 361 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 420
CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV
Sbjct: 420 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 479
Query: 421 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 480
DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG
Sbjct: 480 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 539
Query: 481 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 540
ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA
Sbjct: 540 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 599
Query: 541 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL
Sbjct: 600 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 659
Query: 601 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 660
ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY
Sbjct: 660 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 719
Query: 661 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 720
QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF
Sbjct: 720 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 779
Query: 721 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 780
ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI
Sbjct: 780 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 839
Query: 781 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 840
SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF
Sbjct: 840 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 899
Query: 841 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 900
PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD
Sbjct: 900 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 959
Query: 901 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 960
LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK
Sbjct: 960 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 1019
Query: 961 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1020
DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS
Sbjct: 1020 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1079
Query: 1021 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1080
NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR
Sbjct: 1080 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1139
Query: 1081 GGGSEVITIYS 1091
GGGSEVITIYS
Sbjct: 1140 GGGSEVITIYS 1150
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 2138 bits (5539), Expect = 0.0
Identities = 1076/1091 (98%), Positives = 1076/1091 (98%), Gaps = 15/1091 (1%)
Query: 1 MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNN 60
MSEMSGATTSLATVALDPPSDRTSHPQDVIED DGHKKARNAYLNN
Sbjct: 60 MSEMSGATTSLATVALDPPSDRTSHPQDVIED---------------DGHKKARNAYLNN 104
Query: 61 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 120
SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP
Sbjct: 105 SNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKP 164
Query: 121 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 180
TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS
Sbjct: 165 TKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMS 224
Query: 181 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 240
AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA
Sbjct: 225 AIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRA 284
Query: 241 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 300
AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY
Sbjct: 285 AIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIY 344
Query: 301 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 360
AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT
Sbjct: 345 AGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNAT 404
Query: 361 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 420
CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV
Sbjct: 405 CDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLV 464
Query: 421 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 480
DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG
Sbjct: 465 DITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFG 524
Query: 481 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 540
ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA
Sbjct: 525 ACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIA 584
Query: 541 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 600
KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL
Sbjct: 585 KDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNL 644
Query: 601 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 660
ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY
Sbjct: 645 ACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEY 704
Query: 661 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 720
QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF
Sbjct: 705 QGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTF 764
Query: 721 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 780
ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI
Sbjct: 765 ASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGI 824
Query: 781 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 840
SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF
Sbjct: 825 SHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFF 884
Query: 841 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 900
PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD
Sbjct: 885 PSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKD 944
Query: 901 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 960
LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK
Sbjct: 945 LATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVK 1004
Query: 961 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1020
DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS
Sbjct: 1005 DRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQS 1064
Query: 1021 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1080
NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR
Sbjct: 1065 NVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVR 1124
Query: 1081 GGGSEVITIYS 1091
GGGSEVITIYS
Sbjct: 1125 GGGSEVITIYS 1135
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 2118 bits (5487), Expect = 0.0
Identities = 1066/1082 (98%), Positives = 1072/1082 (99%), Gaps = 2/1082 (0%)
Query: 12 ATVALDPP-SDRTSHPQDVIE-DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 69
A+++ +P +D + QD E DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY
Sbjct: 18 ASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 77
Query: 70 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 129
FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF
Sbjct: 78 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 137
Query: 130 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 189
MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP
Sbjct: 138 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
Query: 190 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 249
AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL
Sbjct: 198 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 257
Query: 250 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 309
KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA
Sbjct: 258 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 317
Query: 310 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 369
PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN
Sbjct: 318 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 377
Query: 370 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 429
VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL
Sbjct: 378 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 437
Query: 430 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 489
VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR
Sbjct: 438 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 497
Query: 490 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 549
DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR
Sbjct: 498 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 557
Query: 550 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 609
VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR
Sbjct: 558 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 617
Query: 610 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 669
TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD
Sbjct: 618 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 677
Query: 670 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 729
GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG
Sbjct: 678 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 737
Query: 730 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 789
LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL
Sbjct: 738 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 797
Query: 790 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 849
GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE
Sbjct: 798 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 857
Query: 850 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 909
GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR
Sbjct: 858 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 917
Query: 910 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 969
IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT
Sbjct: 918 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 977
Query: 970 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1029
SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV
Sbjct: 978 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1037
Query: 1030 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1089
KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI
Sbjct: 1038 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1097
Query: 1090 YS 1091
YS
Sbjct: 1098 YS 1099
>gi|4827006 solute carrier family 12, member 4 isoform a [Homo
sapiens]
Length = 1085
Score = 1669 bits (4321), Expect = 0.0
Identities = 827/1058 (78%), Positives = 931/1058 (87%), Gaps = 7/1058 (0%)
Query: 40 GEHSQLLD-DGHKKARNA--YLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMAN 96
GE ++L D DGH R + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +
Sbjct: 29 GERAELDDSDGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVS 88
Query: 97 YTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTA 156
YTNLTQGAKEHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTA
Sbjct: 89 YTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTA 148
Query: 157 GVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLG 216
GVLQA IVLICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLG
Sbjct: 149 GVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLG 208
Query: 217 TTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFI 276
TTFAAAMYILGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+
Sbjct: 209 TTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFV 268
Query: 277 GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKE 336
GV+YVNKFASLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT
Sbjct: 269 GVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAV 328
Query: 337 INNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKG 396
++N TV ++LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG
Sbjct: 329 VDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKG 388
Query: 397 EIIEK---PSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDA 453
+I+EK PSA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DA
Sbjct: 389 DIVEKHGLPSADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDA 447
Query: 454 QKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 513
QKSIP+GTILAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVI
Sbjct: 448 QKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVI 507
Query: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573
VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAEL
Sbjct: 508 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAEL 567
Query: 574 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICL 633
GILIASLD+VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CL
Sbjct: 568 GILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCL 627
Query: 634 ALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHT 693
ALMF+SSWYYA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHT
Sbjct: 628 ALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHT 687
Query: 694 KNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQ 753
KNWRPQLLVLLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQ
Sbjct: 688 KNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQ 747
Query: 754 TIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARA 813
TIK++ME EKVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RA
Sbjct: 748 TIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRA 807
Query: 814 WKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQ 873
WKTFI TVR TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+Q
Sbjct: 808 WKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQ 867
Query: 874 HKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTL 933
HKVWRKC +RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTL
Sbjct: 868 HKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTL 927
Query: 934 MMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKD 993
MMEQRSQMLR MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+D
Sbjct: 928 MMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRD 987
Query: 994 KYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPP 1053
KYM + + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPP
Sbjct: 988 KYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPP 1047
Query: 1054 RNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1091
RN EGDENYMEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1048 RNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1085
>gi|225579065 solute carrier family 12, member 4 isoform d [Homo
sapiens]
Length = 1079
Score = 1665 bits (4312), Expect = 0.0
Identities = 821/1049 (78%), Positives = 925/1049 (88%), Gaps = 4/1049 (0%)
Query: 46 LDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAK 105
L G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAK
Sbjct: 32 LGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAK 91
Query: 106 EHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIV 165
EHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IV
Sbjct: 92 EHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIV 151
Query: 166 LICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYI 225
LICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYI
Sbjct: 152 LICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYI 211
Query: 226 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFA 285
LGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFA
Sbjct: 212 LGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFA 271
Query: 286 SLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSK 345
SLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++
Sbjct: 272 SLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQ 331
Query: 346 LWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---P 402
LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK P
Sbjct: 332 LWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLP 391
Query: 403 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 462
SA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTI
Sbjct: 392 SADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTI 450
Query: 463 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 522
LAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTC
Sbjct: 451 LAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTC 510
Query: 523 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDL 582
GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+
Sbjct: 511 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDM 570
Query: 583 VAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 642
VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWY
Sbjct: 571 VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWY 630
Query: 643 YAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLV 702
YA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLV
Sbjct: 631 YALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLV 690
Query: 703 LLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAE 762
LLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME E
Sbjct: 691 LLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIE 750
Query: 763 KVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVR 822
KVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR
Sbjct: 751 KVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVR 810
Query: 823 VTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSI 882
TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +
Sbjct: 811 CTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRM 870
Query: 883 RIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQML 942
RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQML
Sbjct: 871 RIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQML 930
Query: 943 RHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQK 1002
R MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM
Sbjct: 931 RQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDP 990
Query: 1003 AKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENY 1062
+ + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENY
Sbjct: 991 SHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENY 1050
Query: 1063 MEFLEVLTEGLERVLLVRGGGSEVITIYS 1091
MEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1051 MEFLEVLTEGLERVLLVRGGGREVITIYS 1079
>gi|225579067 solute carrier family 12, member 4 isoform e [Homo
sapiens]
Length = 1054
Score = 1664 bits (4310), Expect = 0.0
Identities = 820/1046 (78%), Positives = 924/1046 (88%), Gaps = 4/1046 (0%)
Query: 49 GHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHE 108
G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAKEHE
Sbjct: 10 GNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHE 69
Query: 109 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 168
EAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IVLIC
Sbjct: 70 EAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLIC 129
Query: 169 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 228
CCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYILGA
Sbjct: 130 CCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGA 189
Query: 229 IEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 288
IEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFASLF
Sbjct: 190 IEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 249
Query: 289 LACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWG 348
LACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++LW
Sbjct: 250 LACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWS 309
Query: 349 FFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---PSAK 405
FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK PSA
Sbjct: 310 FFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSAD 369
Query: 406 SSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAI 465
+ + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTILAI
Sbjct: 370 APSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAI 428
Query: 466 LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAG 525
+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTCGAG
Sbjct: 429 ITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAG 488
Query: 526 LQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAP 585
LQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+VAP
Sbjct: 489 LQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAP 548
Query: 586 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAI 645
ILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWYYA+
Sbjct: 549 ILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYAL 608
Query: 646 VAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLK 705
VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVLLK
Sbjct: 609 VAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLK 668
Query: 706 LDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVK 765
LDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME EKVK
Sbjct: 669 LDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVK 728
Query: 766 GFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTT 825
GFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR TT
Sbjct: 729 GFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTT 788
Query: 826 AAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIF 885
AAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +RIF
Sbjct: 789 AAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIF 848
Query: 886 TVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHM 945
TVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQMLR M
Sbjct: 849 TVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQM 908
Query: 946 RLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKS 1005
RL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM + +
Sbjct: 909 RLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHA 968
Query: 1006 MEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEF 1065
+ F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENYMEF
Sbjct: 969 PDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEF 1028
Query: 1066 LEVLTEGLERVLLVRGGGSEVITIYS 1091
LEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1029 LEVLTEGLERVLLVRGGGREVITIYS 1054
>gi|225579061 solute carrier family 12, member 4 isoform b [Homo
sapiens]
Length = 1079
Score = 1652 bits (4277), Expect = 0.0
Identities = 821/1058 (77%), Positives = 925/1058 (87%), Gaps = 13/1058 (1%)
Query: 40 GEHSQLLD-DGHKKARNA--YLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMAN 96
GE ++L D DGH R + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +
Sbjct: 29 GERAELDDSDGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVS 88
Query: 97 YTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTA 156
YTNLTQGAKEHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTA
Sbjct: 89 YTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTA 148
Query: 157 GVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLG 216
GVLQA IVLICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLG
Sbjct: 149 GVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLG 208
Query: 217 TTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFI 276
TTFAAAMYILGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+
Sbjct: 209 TTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFV 268
Query: 277 GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKE 336
GV+YVNKFASLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT
Sbjct: 269 GVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAV 328
Query: 337 INNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKG 396
++N TV ++LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG
Sbjct: 329 VDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKG 388
Query: 397 EIIEK---PSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDA 453
+I+EK PSA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DA
Sbjct: 389 DIVEKHGLPSADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDA 447
Query: 454 QKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVI 513
QKSIP+GTILAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVI
Sbjct: 448 QKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVI 507
Query: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573
VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAEL
Sbjct: 508 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAEL 567
Query: 574 GILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICL 633
GILIASLD+VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CL
Sbjct: 568 GILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCL 627
Query: 634 ALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHT 693
ALMF+SSWYYA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHT
Sbjct: 628 ALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHT 687
Query: 694 KNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQ 753
KNWRPQLLVLLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQ
Sbjct: 688 KNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQ 747
Query: 754 TIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARA 813
TIK++ME EKVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RA
Sbjct: 748 TIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRA 807
Query: 814 WKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQ 873
WKTFI TVR TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+Q
Sbjct: 808 WKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQ 867
Query: 874 HKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTL 933
HKVWRKC +RIFTVAQ++DNSIQMKKDLA FLYHLR+EAE H+SDISAYTYERTL
Sbjct: 868 HKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAE------HNSDISAYTYERTL 921
Query: 934 MMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKD 993
MMEQRSQMLR MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+D
Sbjct: 922 MMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRD 981
Query: 994 KYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPP 1053
KYM + + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPP
Sbjct: 982 KYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPP 1041
Query: 1054 RNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1091
RN EGDENYMEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1042 RNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1079
>gi|225579063 solute carrier family 12, member 4 isoform c [Homo
sapiens]
Length = 1087
Score = 1641 bits (4250), Expect = 0.0
Identities = 809/1016 (79%), Positives = 905/1016 (89%), Gaps = 4/1016 (0%)
Query: 79 EEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQ 138
EE+D RPKVSSLL ++ +YTNLTQGAKEHEEAE+ +++ + P MGT MGVYLPCLQ
Sbjct: 73 EELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQ 132
Query: 139 NIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMIS 198
NIFGVILFLRLTW+VGTAGVLQA IVLICCCCT+LTAISMSAIATNGVVPAGGSYFMIS
Sbjct: 133 NIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMIS 192
Query: 199 RALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN 258
R+LGPEFGGAVGLCFYLGTTFAAAMYILGAIEI L YI P AAIF+ A S A LNN
Sbjct: 193 RSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNN 252
Query: 259 MRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCML 318
MRVYGT FL M LVVF+GV+YVNKFASLFLACVI+SIL+IYAG IKS F PP FPVCML
Sbjct: 253 MRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCML 312
Query: 319 GNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPG 378
GNRTLS D+C+KT ++N TV ++LW FFC+S +CD YF+ NNVT I GIPG
Sbjct: 313 GNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPG 372
Query: 379 LASGIITENLWSNYLPKGEIIEK---PSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFP 435
A+G++ ENLWS YL KG+I+EK PSA + + SL YV+ DI TSFT+LVGIFFP
Sbjct: 373 AAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPL-YVVADIATSFTVLVGIFFP 431
Query: 436 SVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDA 495
SVTGIMAGSNRSGDL+DAQKSIP+GTILAI+TTS VY S+VVLFGACIEGVVLRDK+GD
Sbjct: 432 SVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDG 491
Query: 496 VKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSK 555
V NLVVGTL+WPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K
Sbjct: 492 VSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK 551
Query: 556 ANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 615
NGEPTWALLLTA IAELGILIASLD+VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRP
Sbjct: 552 VNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRP 611
Query: 616 RFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLS 675
RF+YYHWALSF+GMS+CLALMF+SSWYYA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLS
Sbjct: 612 RFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLS 671
Query: 676 LSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGS 735
LSAAR+ALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGS
Sbjct: 672 LSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGS 731
Query: 736 VIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHN 795
VI G+FLE+YGEA AAEQTIK++ME EKVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN
Sbjct: 732 VIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHN 791
Query: 796 TVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVW 855
+VV+GWP GWRQSED RAWKTFI TVR TTAAHLALLV KNI+F+PSN E++ EG+IDVW
Sbjct: 792 SVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVW 851
Query: 856 WIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVE 915
WIVHDGGMLMLLPFLL+QHKVWRKC +RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVE
Sbjct: 852 WIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVE 911
Query: 916 VVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDE 975
VVEMH+SDISAYTYERTLMMEQRSQMLR MRL+KTER+REAQLVKDR+S LRL S+ SDE
Sbjct: 912 VVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDE 971
Query: 976 DEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVI 1035
++E+ +K+ MTWT+DKYM + + + F++L++++PDQSNVRRMHTAVKLNEVI
Sbjct: 972 EDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVI 1031
Query: 1036 VNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1091
V +SH+A+LVLLNMPGPPRN EGDENYMEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1032 VTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1087
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 1555 bits (4025), Expect = 0.0
Identities = 775/1099 (70%), Positives = 897/1099 (81%), Gaps = 56/1099 (5%)
Query: 48 DGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEH 107
DG+ K + ++N+++ E+G EY KN+ALFEEEMDT P VSSLL+ +ANYTNL QG++EH
Sbjct: 42 DGNPKESSPFINSTDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREH 101
Query: 108 EEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLI 167
EEAEN GKKKP + P+MGTFMGVYLPCLQNIFGVILFLRLTWVVG AG++++F +V I
Sbjct: 102 EEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFI 161
Query: 168 CCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILG 227
CC CTMLTAISMSAIATNGVVPAGGSY+MISR+LGPEFGGAVGLCFYLGTTFA AMYILG
Sbjct: 162 CCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILG 221
Query: 228 AIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASL 287
IEI L Y+ P AIF ++DA E+AAMLNNMRVYGT L M VVF+GV+YVNKFA +
Sbjct: 222 TIEILLAYLFPAMAIFKAEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALV 281
Query: 288 FLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLW 347
FL CVI+SILAIYAG IKS+F PP+FP+C+LGNRTLS DVC+K N TV ++LW
Sbjct: 282 FLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLW 341
Query: 348 GFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSS 407
G FC SS+F NATCDEYF NNVT IQGIPG ASG+I ENLWS+YL KG I+E+ S
Sbjct: 342 GLFC-SSRFLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTSV 400
Query: 408 DVLGS----LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTIL 463
+ ++H YV D+T+ FTLLVGI+FPSVTGIMAGSNRSGDL+DAQKSIP GTIL
Sbjct: 401 GLADGTPIDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTIL 460
Query: 464 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 523
AI TTS VY+S+VVLFGACIEGVVLRDKFG+AV GNLVVGTL+WPSPWVIVIGSFFSTCG
Sbjct: 461 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 520
Query: 524 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLV 583
AGLQSLTGAPRLLQAI++D I+PFL+VFGH KANGEPTWALLLTA I E+GILIASLD V
Sbjct: 521 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEV 580
Query: 584 APILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYY 643
APILSMFFLMCY+FVNLACA+QTLLRTPNWRPRFRYYHW LSF+GMS+CLALMFI SWYY
Sbjct: 581 APILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYY 640
Query: 644 AIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVL 703
A+VAM+IAG+IYKYIEY+GAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVL
Sbjct: 641 ALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVL 700
Query: 704 LKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEK 763
+++D+D +V HP+LL+ SQLKAGKGLTIVGSV+ G FLEN+ +A AE++I+ LMEAEK
Sbjct: 701 VRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEAEK 760
Query: 764 VKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRV 823
VKGFCQ+V+++ LR+G+SHLIQS GLGG++HNTV++GWP WRQ ED + W+ FI VR
Sbjct: 761 VKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRE 820
Query: 824 TTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIR 883
TTA HLALLV KN+S FP N E+FSEG+IDVWWIVHDGGMLMLLPFLL+ HKVWRKC +R
Sbjct: 821 TTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMR 880
Query: 884 IFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLR 943
IFTVAQ++DNSIQMKKDL TFLYHLRI AEVEVVEMH+SDISAYTYE+TL+MEQRSQ+L+
Sbjct: 881 IFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILK 940
Query: 944 HMRLSKTERDREAQLVKDR-----------NSMLRLT----------------------- 969
M L+K ER+RE Q + D N+ LRL
Sbjct: 941 QMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDSEEKPEEEVQLIHDQ 1000
Query: 970 ----------SIGSDEDEETETYQEKVHMTWTKDKYMA--SRGQKAKSMEGFQDLLNMRP 1017
S G + + E ET EKVH+TWTKDK +A ++G S EG +D +M+P
Sbjct: 1001 SAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKP 1060
Query: 1018 D-----QSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEG 1072
+ QSNVRRMHTAV+LNEVIV KS +AKLVLLNMPGPPRN GDENYMEFLEVLTE
Sbjct: 1061 EWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLTEH 1120
Query: 1073 LERVLLVRGGGSEVITIYS 1091
L+RV+LVRGGG EVITIYS
Sbjct: 1121 LDRVMLVRGGGREVITIYS 1139
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 1555 bits (4025), Expect = 0.0
Identities = 775/1099 (70%), Positives = 897/1099 (81%), Gaps = 56/1099 (5%)
Query: 48 DGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEH 107
DG+ K + ++N+++ E+G EY KN+ALFEEEMDT P VSSLL+ +ANYTNL QG++EH
Sbjct: 19 DGNPKESSPFINSTDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREH 78
Query: 108 EEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLI 167
EEAEN GKKKP + P+MGTFMGVYLPCLQNIFGVILFLRLTWVVG AG++++F +V I
Sbjct: 79 EEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFI 138
Query: 168 CCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILG 227
CC CTMLTAISMSAIATNGVVPAGGSY+MISR+LGPEFGGAVGLCFYLGTTFA AMYILG
Sbjct: 139 CCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILG 198
Query: 228 AIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASL 287
IEI L Y+ P AIF ++DA E+AAMLNNMRVYGT L M VVF+GV+YVNKFA +
Sbjct: 199 TIEILLAYLFPAMAIFKAEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALV 258
Query: 288 FLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLW 347
FL CVI+SILAIYAG IKS+F PP+FP+C+LGNRTLS DVC+K N TV ++LW
Sbjct: 259 FLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLW 318
Query: 348 GFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSS 407
G FC SS+F NATCDEYF NNVT IQGIPG ASG+I ENLWS+YL KG I+E+ S
Sbjct: 319 GLFC-SSRFLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTSV 377
Query: 408 DVLGS----LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTIL 463
+ ++H YV D+T+ FTLLVGI+FPSVTGIMAGSNRSGDL+DAQKSIP GTIL
Sbjct: 378 GLADGTPIDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTIL 437
Query: 464 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 523
AI TTS VY+S+VVLFGACIEGVVLRDKFG+AV GNLVVGTL+WPSPWVIVIGSFFSTCG
Sbjct: 438 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 497
Query: 524 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLV 583
AGLQSLTGAPRLLQAI++D I+PFL+VFGH KANGEPTWALLLTA I E+GILIASLD V
Sbjct: 498 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEV 557
Query: 584 APILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYY 643
APILSMFFLMCY+FVNLACA+QTLLRTPNWRPRFRYYHW LSF+GMS+CLALMFI SWYY
Sbjct: 558 APILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYY 617
Query: 644 AIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVL 703
A+VAM+IAG+IYKYIEY+GAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVL
Sbjct: 618 ALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVL 677
Query: 704 LKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEK 763
+++D+D +V HP+LL+ SQLKAGKGLTIVGSV+ G FLEN+ +A AE++I+ LMEAEK
Sbjct: 678 VRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEAEK 737
Query: 764 VKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRV 823
VKGFCQ+V+++ LR+G+SHLIQS GLGG++HNTV++GWP WRQ ED + W+ FI VR
Sbjct: 738 VKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRE 797
Query: 824 TTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIR 883
TTA HLALLV KN+S FP N E+FSEG+IDVWWIVHDGGMLMLLPFLL+ HKVWRKC +R
Sbjct: 798 TTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMR 857
Query: 884 IFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLR 943
IFTVAQ++DNSIQMKKDL TFLYHLRI AEVEVVEMH+SDISAYTYE+TL+MEQRSQ+L+
Sbjct: 858 IFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILK 917
Query: 944 HMRLSKTERDREAQLVKDR-----------NSMLRLT----------------------- 969
M L+K ER+RE Q + D N+ LRL
Sbjct: 918 QMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDSEEKPEEEVQLIHDQ 977
Query: 970 ----------SIGSDEDEETETYQEKVHMTWTKDKYMA--SRGQKAKSMEGFQDLLNMRP 1017
S G + + E ET EKVH+TWTKDK +A ++G S EG +D +M+P
Sbjct: 978 SAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKP 1037
Query: 1018 D-----QSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEG 1072
+ QSNVRRMHTAV+LNEVIV KS +AKLVLLNMPGPPRN GDENYMEFLEVLTE
Sbjct: 1038 EWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLTEH 1097
Query: 1073 LERVLLVRGGGSEVITIYS 1091
L+RV+LVRGGG EVITIYS
Sbjct: 1098 LDRVMLVRGGGREVITIYS 1116
>gi|123701900 solute carrier family 12 (potassium/chloride
transporters), member 7 [Homo sapiens]
Length = 1083
Score = 1512 bits (3915), Expect = 0.0
Identities = 749/1048 (71%), Positives = 869/1048 (82%), Gaps = 11/1048 (1%)
Query: 48 DGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEH 107
DG+ + + +LNN E+ + KN+ALFEEEMD+ P VSSLLN++ANYTNL+QG EH
Sbjct: 43 DGNPRENSPFLNNVEVEQESFFEGKNMALFEEEMDSNPMVSSLLNKLANYTNLSQGVVEH 102
Query: 108 EEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLI 167
EE E E +++ K P+MGTF+GVYLPCLQNI GVILFLRLTW+VG AGVL++F IV +
Sbjct: 103 EEDE---ESRRREAKAPRMGTFIGVYLPCLQNILGVILFLRLTWIVGVAGVLESFLIVAM 159
Query: 168 CCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILG 227
CC CTMLTAISMSAIATNGVVPAGGSY+MISR+LGPEFGGAVGLCFYLGTTFA AMYILG
Sbjct: 160 CCTCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILG 219
Query: 228 AIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASL 287
IEIFL YI P AAIF ++ A E+AAML+NMRVYGT LVLM LVVF+GV+YVNK A +
Sbjct: 220 TIEIFLTYISPGAAIFQAEAAGGEAAAMLHNMRVYGTCTLVLMALVVFVGVKYVNKLALV 279
Query: 288 FLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLW 347
FLACV++SILAIYAG IKS+F PP PVC+LGNRTLS R D C K I+N + S LW
Sbjct: 280 FLACVVLSILAIYAGVIKSAFDPPDIPVCLLGNRTLSRRSFDACVKAYGIHNNSATSALW 339
Query: 348 GFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---PSA 404
G FCN SQ +A CDEYF+ NNVT IQGIPG ASG+ ENLWS Y G +EK PS
Sbjct: 340 GLFCNGSQP-SAACDEYFIQNNVTEIQGIPGAASGVFLENLWSTYAHAGAFVEKKGVPSV 398
Query: 405 KSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILA 464
++ + YVL DI SFTLLVGI+FPSVTGIMAGSNRSGDLKDAQKSIP GTILA
Sbjct: 399 PVAEESRASALPYVLTDIAASFTLLVGIYFPSVTGIMAGSNRSGDLKDAQKSIPTGTILA 458
Query: 465 ILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGA 524
I+TTSF+YLS +VLFGACIEGVVLRDKFG+A++GNLV+G L+WPSPWVIVIGSFFSTCGA
Sbjct: 459 IVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCGA 518
Query: 525 GLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVA 584
GLQSLTGAPRLLQAIA+D I+PFL+VFGH KANGEPTWALLLT I E GILIASLD VA
Sbjct: 519 GLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLTVLICETGILIASLDSVA 578
Query: 585 PILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYA 644
PILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF++YHW LSF+GMS+CLALMFI SWYYA
Sbjct: 579 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLALMFICSWYYA 638
Query: 645 IVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLL 704
+ AM+IAG IYKYIEY+GAEKEWGDGIRGLSL+AAR+ALLR+E GPPHTKNWRPQ+LV+L
Sbjct: 639 LSAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALLRVEHGPPHTKNWRPQVLVML 698
Query: 705 KLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKV 764
LD + VKHPRLL+F SQLKAGKGLTIVGSV+ G +L+ + EA AE+ I+ LM EK
Sbjct: 699 NLDAEQAVKHPRLLSFTSQLKAGKGLTIVGSVLEGTYLDKHMEAQRAEENIRSLMSTEKT 758
Query: 765 KGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVT 824
KGFCQLVV++ LR+G+SHLIQS GLGG+KHNTV+M WP W+Q ++ +WK F+ TVR T
Sbjct: 759 KGFCQLVVSSSLRDGMSHLIQSAGLGGLKHNTVLMAWPASWKQEDNPFSWKNFVDTVRDT 818
Query: 825 TAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRI 884
TAAH ALLVAKN+ FP N E+F G+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +RI
Sbjct: 819 TAAHQALLVAKNVDSFPQNQERFGGGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRI 878
Query: 885 FTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRH 944
FTVAQ++DNSIQMKKDL FLYHLRI AEVEVVEM ++DISA+TYERTLMMEQRSQML+
Sbjct: 879 FTVAQVDDNSIQMKKDLQMFLYHLRISAEVEVVEMVENDISAFTYERTLMMEQRSQMLKQ 938
Query: 945 MRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR-GQKA 1003
M+LSK E++REAQL+ DRN+ + + T +KV MTWT++K +A + +
Sbjct: 939 MQLSKNEQEREAQLIHDRNTASHTAAAARTQAPPT---PDKVQMTWTREKLIAEKYRSRD 995
Query: 1004 KSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYM 1063
S+ GF+DL +M+PDQSNVRRMHTAVKLN V++NKS +A+LVLLNMPGPP+N +GDENYM
Sbjct: 996 TSLSGFKDLFSMKPDQSNVRRMHTAVKLNGVVLNKSQDAQLVLLNMPGPPKNRQGDENYM 1055
Query: 1064 EFLEVLTEGLERVLLVRGGGSEVITIYS 1091
EFLEVLTEGL RVLLVRGGG EVITIYS
Sbjct: 1056 EFLEVLTEGLNRVLLVRGGGREVITIYS 1083
>gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo
sapiens]
Length = 1021
Score = 239 bits (610), Expect = 1e-62
Identities = 199/743 (26%), Positives = 328/743 (44%), Gaps = 139/743 (18%)
Query: 425 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 484
+F + IFFPS TGI+AG+N SGDLKD +IP GT++AI T+ YL+ G+C
Sbjct: 339 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSC-- 396
Query: 485 GVVLRDKFGDAVKGNLVVG---------------------------------TLSWPSPW 511
V+RD G + + G T+S S +
Sbjct: 397 --VVRDASG-VLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGF 453
Query: 512 --VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTA 568
+I G F +T + L L A ++ Q + +D + P + FG N EP LL
Sbjct: 454 APLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAY 513
Query: 569 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 628
AIA I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G
Sbjct: 514 AIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFG 573
Query: 629 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 688
I + +MF+ +W+ A++A+ + + Y+ Y+ E WG ++ S + A + L E
Sbjct: 574 AIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNE 633
Query: 689 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 748
H KN+RPQ LVL P L+ F L I G V++G + E
Sbjct: 634 VEDHIKNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPEL 689
Query: 749 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 808
+ K+K F V+A LR G+ L+Q+ GLG MK N +V+G+ W+ +
Sbjct: 690 QLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSA 749
Query: 809 EDARAWKTFIG-------------TVRVTTAAHLALLVAKNIS--FFP------------ 841
A + +IG +R+ +++ ++ +I+ F P
Sbjct: 750 HPATV-EDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARVD 808
Query: 842 ----------SNVEQFSEG--NIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQ 889
+ + Q +G ID++W+ DGG+ +L+P+LL + + W KC IR+F Q
Sbjct: 809 PKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVFVGGQ 868
Query: 890 LEDNSIQMKKDLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLS 948
+ + Q +K + + L R+ EV ++ + + A E T E M+ RL+
Sbjct: 869 I-NRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRA---EHTKRFE---DMIAPFRLN 921
Query: 949 KTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEG 1008
+D R+ +++ DEE TK++ + R
Sbjct: 922 DGFKDEATVNEMRRDCPWKIS------DEEI-----------TKNRVKSLR--------- 955
Query: 1009 FQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEV 1068
V+LNE++++ S +A L+++ +P + YM +LE
Sbjct: 956 -------------------QVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLET 996
Query: 1069 LTEGLE-RVLLVRGGGSEVITIY 1090
L++ L V+L+RG V+T Y
Sbjct: 997 LSQDLRPPVILIRGNQENVLTFY 1019
Score = 123 bits (308), Expect = 1e-27
Identities = 69/207 (33%), Positives = 112/207 (54%), Gaps = 21/207 (10%)
Query: 109 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 168
E E T +K P + + G GV + C+ NI+GVIL+LRL W+ AG++ + I+L+
Sbjct: 119 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 178
Query: 169 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 228
T +T +S+SAI+TNG V +GG+YF+ISR+LGPE GG++GL F AM+ +G
Sbjct: 179 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 238
Query: 229 IEIFLVYIVPRAAIFHSDDALKESAA----MLNNMRVYGTAFLVLMVLVVFIGVRYVNKF 284
E D L+E A +N++R+ G + +++ + G+ + +K
Sbjct: 239 AETV-------------RDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKA 285
Query: 285 ASLFLACVIVSILAIYAGAIKSSFAPP 311
LF ++VS +A + + PP
Sbjct: 286 QVLFFLVIMVS----FANYLVGTLIPP 308
>gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo
sapiens]
Length = 1029
Score = 236 bits (601), Expect = 1e-61
Identities = 199/752 (26%), Positives = 328/752 (43%), Gaps = 148/752 (19%)
Query: 425 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 484
+F + IFFPS TGI+AG+N SGDLKD +IP GT++AI T+ YL+ G+C
Sbjct: 338 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSC-- 395
Query: 485 GVVLRDKFGDAVKGNLVVG---------------------------------TLSWPSPW 511
V+RD G + + G T+S S +
Sbjct: 396 --VVRDASG-VLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGF 452
Query: 512 --VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTA 568
+I G F +T + L L A ++ Q + +D + P + FG N EP LL
Sbjct: 453 APLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAY 512
Query: 569 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 628
AIA I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G
Sbjct: 513 AIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFG 572
Query: 629 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 688
I + +MF+ +W+ A++A+ + + Y+ Y+ E WG ++ S + A + L E
Sbjct: 573 AIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNE 632
Query: 689 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 748
H KN+RPQ LVL P L+ F L I G V++G + E
Sbjct: 633 VEDHIKNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPEL 688
Query: 749 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 808
+ K+K F V+A LR G+ L+Q+ GLG MK N +V+G+ W+ +
Sbjct: 689 QLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSA 748
Query: 809 EDARAWKTFIG-------------TVRVTTAAHLALLVAKNIS--FFP------------ 841
A + +IG +R+ +++ ++ +I+ F P
Sbjct: 749 HPATV-EDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARGA 807
Query: 842 -------------------SNVEQFSEG--NIDVWWIVHDGGMLMLLPFLLKQHKVWRKC 880
+ + Q +G ID++W+ DGG+ +L+P+LL + + W KC
Sbjct: 808 RPSVSGALDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKC 867
Query: 881 SIRIFTVAQLEDNSIQMKKDLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMMEQRS 939
IR+F Q+ + Q +K + + L R+ EV ++ + + A E T E
Sbjct: 868 KIRVFVGGQI-NRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRA---EHTKRFE--- 920
Query: 940 QMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR 999
M+ RL+ +D R+ +++ DEE TK++ + R
Sbjct: 921 DMIAPFRLNDGFKDEATVNEMRRDCPWKIS------DEEI-----------TKNRVKSLR 963
Query: 1000 GQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD 1059
V+LNE++++ S +A L+++ +P +
Sbjct: 964 ----------------------------QVRLNEIVLDYSRDAALIVITLPIGRKGKCPS 995
Query: 1060 ENYMEFLEVLTEGLE-RVLLVRGGGSEVITIY 1090
YM +LE L++ L V+L+RG V+T Y
Sbjct: 996 SLYMAWLETLSQDLRPPVILIRGNQENVLTFY 1027
Score = 123 bits (308), Expect = 1e-27
Identities = 69/207 (33%), Positives = 112/207 (54%), Gaps = 21/207 (10%)
Query: 109 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 168
E E T +K P + + G GV + C+ NI+GVIL+LRL W+ AG++ + I+L+
Sbjct: 118 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 177
Query: 169 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 228
T +T +S+SAI+TNG V +GG+YF+ISR+LGPE GG++GL F AM+ +G
Sbjct: 178 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 237
Query: 229 IEIFLVYIVPRAAIFHSDDALKESAA----MLNNMRVYGTAFLVLMVLVVFIGVRYVNKF 284
E D L+E A +N++R+ G + +++ + G+ + +K
Sbjct: 238 AETV-------------RDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKA 284
Query: 285 ASLFLACVIVSILAIYAGAIKSSFAPP 311
LF ++VS +A + + PP
Sbjct: 285 QVLFFLVIMVS----FANYLVGTLIPP 307
>gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo
sapiens]
Length = 1030
Score = 236 bits (601), Expect = 1e-61
Identities = 199/752 (26%), Positives = 328/752 (43%), Gaps = 148/752 (19%)
Query: 425 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 484
+F + IFFPS TGI+AG+N SGDLKD +IP GT++AI T+ YL+ G+C
Sbjct: 339 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSC-- 396
Query: 485 GVVLRDKFGDAVKGNLVVG---------------------------------TLSWPSPW 511
V+RD G + + G T+S S +
Sbjct: 397 --VVRDASG-VLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGF 453
Query: 512 --VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTA 568
+I G F +T + L L A ++ Q + +D + P + FG N EP LL
Sbjct: 454 APLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAY 513
Query: 569 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 628
AIA I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G
Sbjct: 514 AIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFG 573
Query: 629 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 688
I + +MF+ +W+ A++A+ + + Y+ Y+ E WG ++ S + A + L E
Sbjct: 574 AIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNE 633
Query: 689 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 748
H KN+RPQ LVL P L+ F L I G V++G + E
Sbjct: 634 VEDHIKNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPEL 689
Query: 749 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 808
+ K+K F V+A LR G+ L+Q+ GLG MK N +V+G+ W+ +
Sbjct: 690 QLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSA 749
Query: 809 EDARAWKTFIG-------------TVRVTTAAHLALLVAKNIS--FFP------------ 841
A + +IG +R+ +++ ++ +I+ F P
Sbjct: 750 HPATV-EDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARGA 808
Query: 842 -------------------SNVEQFSEG--NIDVWWIVHDGGMLMLLPFLLKQHKVWRKC 880
+ + Q +G ID++W+ DGG+ +L+P+LL + + W KC
Sbjct: 809 RPSVSGALDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKC 868
Query: 881 SIRIFTVAQLEDNSIQMKKDLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMMEQRS 939
IR+F Q+ + Q +K + + L R+ EV ++ + + A E T E
Sbjct: 869 KIRVFVGGQI-NRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRA---EHTKRFE--- 921
Query: 940 QMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR 999
M+ RL+ +D R+ +++ DEE TK++ + R
Sbjct: 922 DMIAPFRLNDGFKDEATVNEMRRDCPWKIS------DEEI-----------TKNRVKSLR 964
Query: 1000 GQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD 1059
V+LNE++++ S +A L+++ +P +
Sbjct: 965 ----------------------------QVRLNEIVLDYSRDAALIVITLPIGRKGKCPS 996
Query: 1060 ENYMEFLEVLTEGLE-RVLLVRGGGSEVITIY 1090
YM +LE L++ L V+L+RG V+T Y
Sbjct: 997 SLYMAWLETLSQDLRPPVILIRGNQENVLTFY 1028
Score = 123 bits (308), Expect = 1e-27
Identities = 69/207 (33%), Positives = 112/207 (54%), Gaps = 21/207 (10%)
Query: 109 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 168
E E T +K P + + G GV + C+ NI+GVIL+LRL W+ AG++ + I+L+
Sbjct: 119 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 178
Query: 169 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 228
T +T +S+SAI+TNG V +GG+YF+ISR+LGPE GG++GL F AM+ +G
Sbjct: 179 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 238
Query: 229 IEIFLVYIVPRAAIFHSDDALKESAA----MLNNMRVYGTAFLVLMVLVVFIGVRYVNKF 284
E D L+E A +N++R+ G + +++ + G+ + +K
Sbjct: 239 AETV-------------RDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKA 285
Query: 285 ASLFLACVIVSILAIYAGAIKSSFAPP 311
LF ++VS +A + + PP
Sbjct: 286 QVLFFLVIMVS----FANYLVGTLIPP 308
>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
transporters), member 2 [Homo sapiens]
Length = 1212
Score = 223 bits (567), Expect = 1e-57
Identities = 147/421 (34%), Positives = 215/421 (51%), Gaps = 46/421 (10%)
Query: 425 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 484
+F + IFFP+ TGI+AG+N SGDL D Q +IP GT+LAIL T+ VY+ V G+C
Sbjct: 486 TFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSC-- 543
Query: 485 GVVLRDKFGD---------------AVKGNL-------------------VVGTLSWPSP 510
V+RD G+ A K N V+ +S +P
Sbjct: 544 --VVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTP 601
Query: 511 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVF--GHSKANGEPTWALLLTA 568
+I G F +T + L SL AP++ QA+ KDNI P ++F G+ K N EP +LT
Sbjct: 602 -LISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGK-NNEPLRGYILTF 659
Query: 569 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 628
IA ILIA L+++API+S FFL Y +N + +L ++P WRP F+YY+ +S +G
Sbjct: 660 LIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLG 719
Query: 629 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 688
+C +MF+ +W+ A++ VI +Y Y+ Y+ + WG + L+ A +RL
Sbjct: 720 AILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSG 779
Query: 689 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 748
H KN+RPQ LV+ P LL GL I G V +G + E
Sbjct: 780 VEDHVKNFRPQCLVMTGAPN----SRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEM 835
Query: 749 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 808
+ + + K+K F V A LREG +L+Q+ GLG MK NT+V+G+ W Q+
Sbjct: 836 SIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQA 895
Query: 809 E 809
+
Sbjct: 896 D 896
Score = 121 bits (303), Expect = 4e-27
Identities = 62/172 (36%), Positives = 106/172 (61%), Gaps = 9/172 (5%)
Query: 125 QMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIAT 184
+ G GV + C+ NI+GV+LF+RL+W+VG AG+ + ++++ T +T +S SAIAT
Sbjct: 284 KFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIAT 343
Query: 185 NGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFH 244
NG V GG+Y++ISR+LGPEFGGA+GL F A AMY++G E +V ++ +I
Sbjct: 344 NGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAET-VVELLKEHSILM 402
Query: 245 SDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSI 296
D+ +N++R+ G +V+++ + G+ + K + L ++++I
Sbjct: 403 IDE--------INDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAI 446
Score = 76.6 bits (187), Expect = 1e-13
Identities = 58/245 (23%), Positives = 110/245 (44%), Gaps = 55/245 (22%)
Query: 849 EGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQM-KKDLATFLYH 907
+ IDVWW+ DGG+ +L+P+LL K W+ C IR+F ++ N I ++ +AT L
Sbjct: 1021 KNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKI--NRIDHDRRAMATLLSK 1078
Query: 908 LRIE-AEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSML 966
RI+ +++ V+ DI+ + ++ + +++ RL + +++++ +
Sbjct: 1079 FRIDFSDIMVL----GDINTKPKKENIIAFE--EIIEPYRLHEDDKEQDIADKMKEDEPW 1132
Query: 967 RLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMH 1026
R+T D E E Y+ K +
Sbjct: 1133 RIT------DNELELYKTKT---------------------------------------Y 1147
Query: 1027 TAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEV 1086
++LNE++ S A ++++++P + YM +LE L++ L +LLVRG V
Sbjct: 1148 RQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSV 1207
Query: 1087 ITIYS 1091
+T YS
Sbjct: 1208 LTFYS 1212
>gi|134254459 sodium potassium chloride cotransporter 2 [Homo
sapiens]
Length = 1099
Score = 211 bits (538), Expect = 2e-54
Identities = 142/421 (33%), Positives = 207/421 (49%), Gaps = 50/421 (11%)
Query: 426 FTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEG 485
F + IFFP+ TGI+AG+N SGDL+D Q +IP GT+LAI T+ YL + GAC
Sbjct: 380 FFSVFAIFFPAATGILAGANISGDLEDPQDAIPRGTMLAIFITTVAYLGVAICVGAC--- 436
Query: 486 VVLRDKFGDA---------VKGNLVVG----------------------TLSWPSPW--V 512
V+RD G+ G+ G +S S + +
Sbjct: 437 -VVRDATGNMNDTIISGMNCNGSAACGLGYDFSRCRHEPCQYGLMNNFQVMSMVSGFGPL 495
Query: 513 IVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVF--GHSKANGEPTWALLLTAAI 570
I G F +T + L SL AP++ QA+ KDNI L+ F G+ K N EP +LT I
Sbjct: 496 ITAGIFSATLSSALASLVSAPKVFQALCKDNIYKALQFFAKGYGK-NNEPLRGYILTFLI 554
Query: 571 AELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMS 630
A ILIA L+ +API+S FFL Y +N +C + ++P WRP + Y+ +S G
Sbjct: 555 AMAFILIAELNTIAPIISNFFLASYALINFSCFHASYAKSPGWRPAYGIYNMWVSLFGAV 614
Query: 631 ICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGP 690
+C A+MF+ +W+ A++ VI +Y Y+ + + WG + LS +A L L
Sbjct: 615 LCCAVMFVINWWAAVITYVIEFFLYVYVTCKKPDVNWGSSTQALSYVSALDNALELTTVE 674
Query: 691 PHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGN---FLENYGE 747
H KN+RPQ +VL + P LL GL I V VG ++
Sbjct: 675 DHVKNFRPQCIVL----TGGPMTRPALLDITHAFTKNSGLCICCEVFVGPRKLCVKEMNS 730
Query: 748 ALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQ 807
+A +Q + K+K F V A R+G+ L+Q+ GLG MK NT+V+G+ WR+
Sbjct: 731 GMAKKQA---WLIKNKIKAFYAAVAADCFRDGVRSLLQASGLGRMKPNTLVIGYKKNWRK 787
Query: 808 S 808
+
Sbjct: 788 A 788
Score = 132 bits (331), Expect = 2e-30
Identities = 83/253 (32%), Positives = 135/253 (53%), Gaps = 25/253 (9%)
Query: 57 YLNNSNYEEGDEYFDKNLALFEEEMDTRPKVS-SLLNRMANYTNLTQGAKEHEEAENITE 115
Y N+ G + +L E++ V+ S +R+AN G E+AEN +
Sbjct: 114 YYRNTGSISGPKVNRPSLLEIHEQLAKNVAVTPSSADRVAN----GDGIPGDEQAENKED 169
Query: 116 GKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLT 175
+ K G GV + C+ NI+GV+LF+RL+W+VG AG+ I+L+ T +T
Sbjct: 170 DQAGVVK---FGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAGIGLGVLIILLSTMVTSIT 226
Query: 176 AISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVY 235
+S SAIATNG V GG+Y++ISR+LGPEFGG++GL F A AMY++G E +
Sbjct: 227 GLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVV-- 284
Query: 236 IVPRAAIFHSDDALKESAAML----NNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLAC 291
D LKES +M+ N++R+ G+ +V+++ + G+ + K + L
Sbjct: 285 -----------DLLKESDSMMVDPTNDIRIIGSITVVILLGISVAGMEWEAKAQVILLVI 333
Query: 292 VIVSILAIYAGAI 304
++++I + G +
Sbjct: 334 LLIAIANFFIGTV 346
Score = 85.5 bits (210), Expect = 2e-16
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 55/275 (20%)
Query: 819 GTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWR 878
G++ + + H+ K + ++ +G IDVWW+ DGG+ +L+P++L K W+
Sbjct: 878 GSINTSQSMHVGEFNQKLVEASTQFKKKQEKGTIDVWWLFDDGGLTLLIPYILTLRKKWK 937
Query: 879 KCSIRIFTVAQLEDNSIQMKK-DLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMME 936
C +RI+ ++ N I+ +K +A+ L RI+ A++ ++ DI+ + + +
Sbjct: 938 DCKLRIYVGGKI--NRIEEEKIVMASLLSKFRIKFADIHII----GDINIRPNKESWKVF 991
Query: 937 QRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYM 996
+ +M+ RL ++ +D R + ++T D E E +EK
Sbjct: 992 E--EMIEPYRLHESCKDLTTAEKLKRETPWKIT------DAELEAVKEK----------- 1032
Query: 997 ASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNP 1056
+ V+LNE++ S A L++L++P +
Sbjct: 1033 ----------------------------SYRQVRLNELLQEHSRAANLIVLSLPVARKGS 1064
Query: 1057 EGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1091
D YM +LE+LT+ L VLLVRG V+T YS
Sbjct: 1065 ISDLLYMAWLEILTKNLPPVLLVRGNHKNVLTFYS 1099
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 195 bits (496), Expect = 2e-49
Identities = 130/412 (31%), Positives = 214/412 (51%), Gaps = 37/412 (8%)
Query: 403 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 462
S+ D LG+ E +F + + F TGIMAG+N SG+LKD ++IP+GTI
Sbjct: 244 SSTLKDNLGAGYAEDYTTGAVMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTI 303
Query: 463 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 522
+A+ T FVY+ L + +L++ +G +L WP +++IG + +
Sbjct: 304 VAVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISL------WPP--LVLIGIYATAL 355
Query: 523 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTA-AIAELGILIASLD 581
A + SL GA R+L A+A+D++ + + G WA +L + + +L +L L+
Sbjct: 356 SASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLN 415
Query: 582 LVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSW 641
+A ++++F+L+ Y V+L+C PN+RP F + W +G++ CL +MF+ S
Sbjct: 416 TLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISP 475
Query: 642 YYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLL 701
A ++++ G++ + +G WG + L R LLRL+ H K WRPQLL
Sbjct: 476 GAAGGSLLLMGLLAALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLL 535
Query: 702 VLLKLDEDLHVKHPR----LLTFASQLKAGKGLTIVGSVIVGNF--------LENYGEAL 749
+L V +PR LL A+QLK G GL ++G V +G+ YG L
Sbjct: 536 LL--------VGNPRGALPLLRLANQLKKG-GLYVLGHVTLGDLDSLPSDPVQPQYGAWL 586
Query: 750 AAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGW 801
+ L++ +VK F L ++ +R+G HL++ GLGGMK NT+V+G+
Sbjct: 587 S-------LVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGF 631
Score = 112 bits (279), Expect = 2e-24
Identities = 53/109 (48%), Positives = 77/109 (70%)
Query: 125 QMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIAT 184
++ TF+GV +P + ++F +++FLR+ +VVG AG+LQA A++L+ LT +S+ AIAT
Sbjct: 36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIAT 95
Query: 185 NGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFL 233
NG V GG+YFMISR LGPE GG++GL FYL A+ +LG +E L
Sbjct: 96 NGAVQGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVL 144
Score = 31.6 bits (70), Expect = 4.3
Identities = 16/38 (42%), Positives = 19/38 (50%)
Query: 1044 LVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG 1081
L L +P PP +P Y+ LE LT L LLV G
Sbjct: 868 LTFLYLPRPPADPARYPRYLALLETLTRDLGPTLLVHG 905
>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
Length = 714
Score = 104 bits (260), Expect = 4e-22
Identities = 59/176 (33%), Positives = 102/176 (57%), Gaps = 9/176 (5%)
Query: 425 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 484
SF + G+FFP+ TG+MAG N GDL++ SIP+G++ A+ + F+Y+ V L GA
Sbjct: 232 SFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIVFVFLLGAICT 291
Query: 485 GVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNI 544
LR F A K +L+ ++ ++G + S+ + + L GAPR+LQ IA++ +
Sbjct: 292 REALRYDFLIAEKVSLM--------GFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKV 343
Query: 545 IPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVN 599
IP L G K N P A+ LT+ + + + ++++API+++ F++ Y+ V+
Sbjct: 344 IPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVD 399
Score = 90.9 bits (224), Expect = 6e-18
Identities = 62/207 (29%), Positives = 94/207 (45%), Gaps = 27/207 (13%)
Query: 107 HEEAENITEGKKKPTKTPQM--------GTFMGVYLPCLQNIFGVILFLRLTWVVGTAGV 158
HE A+ + +P Q+ GT+ GV+ C+ NIFGV+LFLR W+VG GV
Sbjct: 12 HEAAQQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGV 71
Query: 159 LQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTT 218
L +V ++T +S + + +GG Y MIS LG + GG +GL + G
Sbjct: 72 LLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGGTIGLLYVFGQC 131
Query: 219 FAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVL--VVFI 276
A AMYI G E ++ + + N V G + VL+ L +
Sbjct: 132 VAGAMYITGFAE-----------------SISDLLGLGNIWAVRGISVAVLLALLGINLA 174
Query: 277 GVRYVNKFASLFLACVIVSILAIYAGA 303
GV+++ + L L + VS L G+
Sbjct: 175 GVKWIIRLQLLLLFLLAVSTLDFVVGS 201
Score = 33.1 bits (74), Expect = 1.5
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 16/79 (20%)
Query: 613 WRPRFRYYH-----WALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEW 667
WR +Y W +S +G L +MF+ W Y +V M +A ++Y YI
Sbjct: 582 WRRSTSFYTHMCNPW-VSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYI--------- 631
Query: 668 GDGIRGLSL-SAARFALLR 685
G GL L SA+ F+ R
Sbjct: 632 GRASPGLHLGSASNFSFFR 650
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 47.0 bits (110), Expect = 1e-04
Identities = 51/211 (24%), Positives = 83/211 (39%), Gaps = 21/211 (9%)
Query: 400 EKPSAKSSDVLGS-----LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQ 454
E PS + + G+ L T F VG + TG ++++ Q
Sbjct: 274 EPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTG--------EEVRNPQ 325
Query: 455 KSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVI 513
K+IPIG + ++L Y + +L +K V V W P+ +V+
Sbjct: 326 KAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYV----GWGPAKYVV 381
Query: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573
GS + + L S+ PR+L A+A+D ++ R P A L I+ L
Sbjct: 382 AAGSLCALSTSLLGSMFPLPRILFAMARDGLL--FRFLARVSKRQSPVAATLTAGVISAL 439
Query: 574 GILIASLDLVAPILSMFFLMCYLFVNLACAL 604
+ L + ++S+ LM Y V AC L
Sbjct: 440 MAFLFDLKALVDMMSIGTLMAYSLV-AACVL 469
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 20/211 (9%)
Query: 400 EKPSAKSSDVLGS-----LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQ 454
E PS + + G+ L T F VG + TG ++++ Q
Sbjct: 234 EPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTG--------EEVRNPQ 285
Query: 455 KSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVI 513
K+IPIG + ++L Y + +L +K V V W P+ +V+
Sbjct: 286 KAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYV----GWGPAKYVV 341
Query: 514 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 573
GS + + L S+ PR++ A+A+D ++ F + + P A L + A+A L
Sbjct: 342 AAGSLCALSTSLLGSIFPMPRVIYAMAEDGLL-FKCLAQINSKTKTPIIATLSSGAVAAL 400
Query: 574 GILIASLDLVAPILSMFFLMCYLFVNLACAL 604
+ L + ++S+ LM Y V AC L
Sbjct: 401 MAFLFDLKALVDMMSIGTLMAYSLV-AACVL 430
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 40.4 bits (93), Expect = 0.009
Identities = 48/208 (23%), Positives = 89/208 (42%), Gaps = 27/208 (12%)
Query: 418 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLS--- 474
VL T F VG + TG ++K+ QK+IP+G + ++L Y
Sbjct: 255 VLSGAATCFYAFVGFDCIATTG--------EEVKNPQKAIPVGIVASLLICFIAYFGVSA 306
Query: 475 --NVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWP-SPWVIVIGSFFSTCGAGLQSLTG 531
+++ C++ DA K + W + + + +GS + + L S+
Sbjct: 307 ALTLMMPYFCLDN---NSPLPDAFK------HVGWEGAKYAVAVGSLCALSASLLGSMFP 357
Query: 532 APRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFF 591
PR++ A+A+D ++ F + + P A L + A+A + + L + ++S+
Sbjct: 358 MPRVIYAMAEDGLL-FKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGT 416
Query: 592 LMCYLFVNLACALQTLLRTPNWRPRFRY 619
L+ Y V AC L +LR +P Y
Sbjct: 417 LLAYSLV-AACVL--VLRYQPEQPNLVY 441
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 37.4 bits (85), Expect = 0.078
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 449 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 507
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
Query: 508 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 567
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
Query: 568 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 615
+ +L+ + +S +CY L L R RP
Sbjct: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 1/124 (0%)
Query: 931 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW 990
RT E+R + S+T+ Q +K+ + +DEDE+ + EK H +
Sbjct: 246 RTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 305
Query: 991 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP 1050
KD A R + K E ++ D+ E K AK V+ +
Sbjct: 306 PKD-LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKT 364
Query: 1051 GPPR 1054
PP+
Sbjct: 365 HPPK 368
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 1/124 (0%)
Query: 931 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW 990
RT E+R + S+T+ Q +K+ + +DEDE+ + EK H +
Sbjct: 230 RTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 289
Query: 991 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP 1050
KD A R + K E ++ D+ E K AK V+ +
Sbjct: 290 PKD-LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKT 348
Query: 1051 GPPR 1054
PP+
Sbjct: 349 HPPK 352
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 36.2 bits (82), Expect = 0.17
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 418 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVV 477
VL T F +G + TG A K+ SIP +++ Y+S V
Sbjct: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
Query: 478 LFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 537
+ + + ++ + V + + +V+ IGS + L SL PR++
Sbjct: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
Query: 538 AIAKDNIIPFLRVFGHSKANGE-PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYL 596
A+A D ++ R H + E P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
Query: 597 FVNLACAL 604
V++ L
Sbjct: 421 LVSVCVLL 428
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 35.4 bits (80), Expect = 0.30
Identities = 43/191 (22%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 416 EYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSN 475
E +L T F VG + TG A ++ Q+SIP+G ++++ Y +
Sbjct: 251 EGILRGAATCFYAFVGFDCIATTGEEA--------QNPQRSIPMGIVISLSVCFLAYFAV 302
Query: 476 VVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVIVIGSFFSTCGAGLQSLTGAPR 534
+ L+ + + L +G W P+ +V+ +GS + + L S+ PR
Sbjct: 303 SSALTLMMPYYQLQPE-SPLPEAFLYIG---WAPARYVVAVGSLCALSTSLLGSMFPMPR 358
Query: 535 LLQAIAKDNIIPFLRVFGH-SKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLM 593
++ A+A+D ++ RV P A +++ IA + L + ++S+ L+
Sbjct: 359 VIYAMAEDGLL--FRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLL 416
Query: 594 CYLFVNLACAL 604
Y V++ C L
Sbjct: 417 AYSLVSI-CVL 426
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 35.4 bits (80), Expect = 0.30
Identities = 43/191 (22%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 416 EYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSN 475
E +L T F VG + TG A ++ Q+SIP+G ++++ Y +
Sbjct: 251 EGILRGAATCFYAFVGFDCIATTGEEA--------QNPQRSIPMGIVISLSVCFLAYFAV 302
Query: 476 VVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVIVIGSFFSTCGAGLQSLTGAPR 534
+ L+ + + L +G W P+ +V+ +GS + + L S+ PR
Sbjct: 303 SSALTLMMPYYQLQPE-SPLPEAFLYIG---WAPARYVVAVGSLCALSTSLLGSMFPMPR 358
Query: 535 LLQAIAKDNIIPFLRVFGH-SKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLM 593
++ A+A+D ++ RV P A +++ IA + L + ++S+ L+
Sbjct: 359 VIYAMAEDGLL--FRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLL 416
Query: 594 CYLFVNLACAL 604
Y V++ C L
Sbjct: 417 AYSLVSI-CVL 426
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,279,147
Number of Sequences: 37866
Number of extensions: 1627302
Number of successful extensions: 4650
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 4551
Number of HSP's gapped (non-prelim): 100
length of query: 1091
length of database: 18,247,518
effective HSP length: 113
effective length of query: 978
effective length of database: 13,968,660
effective search space: 13661349480
effective search space used: 13661349480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.