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Search of human proteins with 149274607
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 754 0.0
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 367 e-102
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 324 9e-89
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 324 9e-89
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 324 9e-89
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 324 9e-89
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 324 9e-89
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 324 9e-89
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 320 2e-87
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 320 2e-87
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 142 5e-34
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 124 1e-28
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 118 7e-27
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 110 2e-24
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 107 1e-23
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 107 2e-23
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 107 2e-23
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 106 4e-23
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 103 2e-22
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 103 2e-22
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 100 2e-21
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 100 2e-21
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 98 1e-20
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 97 2e-20
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 97 2e-20
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 97 3e-20
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 94 1e-19
gi|11225256 uncoupling protein 1 [Homo sapiens] 89 6e-18
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 88 1e-17
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 88 1e-17
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 754 bits (1946), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MGAQPGEPQNTCSRIQTLFRRVKTLLIKAPPPPQPPPPPPSWNPGCTHVYGYAFGHMHDN 60
MGAQPGEPQNTCSRIQTLFRRVKTLLIKAPPPPQPPPPPPSWNPGCTHVYGYAFGHMHDN
Sbjct: 1 MGAQPGEPQNTCSRIQTLFRRVKTLLIKAPPPPQPPPPPPSWNPGCTHVYGYAFGHMHDN 60
Query: 61 NLEHLPSQQVLDTGEQLMVPVEVLEVDNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYM 120
NLEHLPSQQVLDTGEQLMVPVEVLEVDNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYM
Sbjct: 61 NLEHLPSQQVLDTGEQLMVPVEVLEVDNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYM 120
Query: 121 QVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGI 180
QVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGI
Sbjct: 121 QVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGI 180
Query: 181 QGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRA 240
QGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRA
Sbjct: 181 QGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRA 240
Query: 241 LYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMAS 300
LYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMAS
Sbjct: 241 LYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMAS 300
Query: 301 YPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVV 360
YPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVV
Sbjct: 301 YPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVV 360
Query: 361 YEAMKKTLGI 370
YEAMKKTLGI
Sbjct: 361 YEAMKKTLGI 370
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 367 bits (942), Expect = e-102
Identities = 196/304 (64%), Positives = 235/304 (77%), Gaps = 3/304 (0%)
Query: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
VLD GE L VP E + + +W K L++GA+AGAVSRTGTAPLDR KV+MQV++SKTN
Sbjct: 162 VLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTN 221
Query: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
N+LGGL+SMV EGG RSLWRGNGINVLKIAPE AIKF +EQ K G Q + QE
Sbjct: 222 RLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQE 281
Query: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
R +AGSLA A +QT+I PMEVLKTRLTLRRTGQYKGLLDCAR+IL+REG RA YRGYLPN
Sbjct: 282 RFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPN 341
Query: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
+LGIIPYA DLAVYE L+ +W++ D DP LV L+ T+S+TCGQ+ASYPL LVR
Sbjct: 342 VLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVR 401
Query: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TRMQAQ ++EG +M G+L+ IL+Q+G GLYRG+ P +KV+PA ISYVVYE MK+
Sbjct: 402 TRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Query: 367 TLGI 370
LG+
Sbjct: 462 ALGV 465
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 324 bits (830), Expect = 9e-89
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 163 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 222
Query: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 223 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 282
Query: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 283 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 342
Query: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
Query: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
Query: 367 TLGI 370
TLG+
Sbjct: 463 TLGV 466
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 324 bits (830), Expect = 9e-89
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 197 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 256
Query: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 257 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 316
Query: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 317 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 376
Query: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 377 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 436
Query: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 437 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496
Query: 367 TLGI 370
TLG+
Sbjct: 497 TLGV 500
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 324 bits (830), Expect = 9e-89
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 183 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 242
Query: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 243 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 302
Query: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 303 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 362
Query: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 363 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 422
Query: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 423 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 482
Query: 367 TLGI 370
TLG+
Sbjct: 483 TLGV 486
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 324 bits (830), Expect = 9e-89
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 163 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 222
Query: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 223 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 282
Query: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 283 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 342
Query: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
Query: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
Query: 367 TLGI 370
TLG+
Sbjct: 463 TLGV 466
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 324 bits (830), Expect = 9e-89
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 60 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 119
Query: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 120 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 179
Query: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 180 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 239
Query: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 240 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 299
Query: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 300 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 359
Query: 367 TLGI 370
TLG+
Sbjct: 360 TLGV 363
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 324 bits (830), Expect = 9e-89
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 197 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 256
Query: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 257 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 316
Query: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 317 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 376
Query: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 377 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 436
Query: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 437 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496
Query: 367 TLGI 370
TLG+
Sbjct: 497 TLGV 500
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 320 bits (819), Expect = 2e-87
Identities = 166/303 (54%), Positives = 218/303 (71%), Gaps = 3/303 (0%)
Query: 71 LDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNF 129
+D G+ L +P E E + K W + LL+G +AGAVSRT TAPLDR K+ MQV+ SK++
Sbjct: 172 IDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDK 231
Query: 130 TNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQER 189
N+ GG + MV+EGG RSLWRGNG NV+KIAPE A+KF +EQ K ER
Sbjct: 232 MNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFER 291
Query: 190 LLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNM 249
++GS+A A +QT I PMEV+KTRL + +TGQY G+ DCA++IL+ EG A Y+GY+PN+
Sbjct: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 351
Query: 250 LGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRT 308
LGIIPYA DLAVYE+L+ +W+ + +D +P +V L LS+TCGQ+ASYPL LVRT
Sbjct: 352 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRT 411
Query: 309 RMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKT 367
RMQAQ +EGS M G+ +RI++++G GLYRG+TP +KVLPA GISYVVYE MK+T
Sbjct: 412 RMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQT 471
Query: 368 LGI 370
LG+
Sbjct: 472 LGV 474
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 320 bits (819), Expect = 2e-87
Identities = 166/303 (54%), Positives = 218/303 (71%), Gaps = 3/303 (0%)
Query: 71 LDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNF 129
+D G+ L +P E E + K W + LL+G +AGAVSRT TAPLDR K+ MQV+ SK++
Sbjct: 153 IDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDK 212
Query: 130 TNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQER 189
N+ GG + MV+EGG RSLWRGNG NV+KIAPE A+KF +EQ K ER
Sbjct: 213 MNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFER 272
Query: 190 LLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNM 249
++GS+A A +QT I PMEV+KTRL + +TGQY G+ DCA++IL+ EG A Y+GY+PN+
Sbjct: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 332
Query: 250 LGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRT 308
LGIIPYA DLAVYE+L+ +W+ + +D +P +V L LS+TCGQ+ASYPL LVRT
Sbjct: 333 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRT 392
Query: 309 RMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKT 367
RMQAQ +EGS M G+ +RI++++G GLYRG+TP +KVLPA GISYVVYE MK+T
Sbjct: 393 RMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQT 452
Query: 368 LGI 370
LG+
Sbjct: 453 LGV 455
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 142 bits (358), Expect = 5e-34
Identities = 94/286 (32%), Positives = 152/286 (53%), Gaps = 11/286 (3%)
Query: 87 DNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFR 146
D+++ L LL GA+AGA+++T APLDR K+ QV S + + L GF
Sbjct: 29 DHRQVL-SSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFL 87
Query: 147 SLWRGNGINVLKIAPEYAIKFSVFEQCKNY---FCGIQGS--PPFQERLLAGSLAVAISQ 201
SLWRGN ++++ P AI+FS E+ K + G +G PP+ RL AG+LA +
Sbjct: 88 SLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPW-PRLFAGALAGTTAA 146
Query: 202 TLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLA 261
+L P+++++ R+ + Y + +I + EG + LY G++P +LG+IPYA
Sbjct: 147 SLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFF 206
Query: 262 VYEMLQCFWVK-SGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSN 320
YE L+ + SGR P + + + GQ ASYPL +VR RMQ
Sbjct: 207 TYETLKSLHREYSGRRQPYPFERMIFGA--CAGLIGQSASYPLDVVRRRMQTAGVTGYPR 264
Query: 321 PTMRGVLQRILAQQGWL-GLYRGMTPTLLKVLPAGGISYVVYEAMK 365
++ L+ I+ ++G + GLY+G++ +K A GIS+ ++ M+
Sbjct: 265 ASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
Score = 35.0 bits (79), Expect = 0.11
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 283 LVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRG 342
L SL L+ + A PL + Q + R VL +G+L L+RG
Sbjct: 34 LSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFR-VLYYTYLNEGFLSLWRG 92
Query: 343 MTPTLLKVLPAGGISYVVYEAMKKTLG 369
+ T+++V+P I + +E K+ LG
Sbjct: 93 NSATMVRVVPYAAIQFSAHEEYKRILG 119
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 124 bits (311), Expect = 1e-28
Identities = 87/289 (30%), Positives = 142/289 (49%), Gaps = 21/289 (7%)
Query: 97 LSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINV 156
L+G +AG ++T APLDR KV +Q ++ + L+++ Q+ GF L++GNG +
Sbjct: 41 LAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMM 100
Query: 157 LKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTL 216
++I P AI+F FE K G RL+AGS+A + P+++++ RL
Sbjct: 101 IRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAF 160
Query: 217 RRTGQ--YKGLLDCARQILQRE-GTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKS 273
+ G+ Y G++ + I +E G YRG +P +LG+ PYA + L+ +
Sbjct: 161 QVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSH 220
Query: 274 -----GRDMGD-PSGLVSLSSVTLSTTCG-------QMASYPLTLVRTRMQAQDTVEGSN 320
GR D P+ LV + V L CG Q SYP + R RMQ +
Sbjct: 221 APTLLGRPSSDNPNVLVLKTHVNL--LCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFE 278
Query: 321 P--TMRGVLQRILAQQG-WLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
TMR ++ + G GLYRG++ ++ +P+ +++ YE MK+
Sbjct: 279 KCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327
Score = 58.9 bits (141), Expect = 7e-09
Identities = 52/198 (26%), Positives = 90/198 (45%), Gaps = 25/198 (12%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVY-SSKTNFTNLLGGLQSM-VQEGGFRSLWRGNG 153
L++G+MAG + T PLD +V + + ++T ++ +++ +EGGF +RG
Sbjct: 134 LMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLM 193
Query: 154 INVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQER----------------LLAGSLAV 197
+L +AP + F F K+ G+ +P R LL G +A
Sbjct: 194 PTILGMAPYAGVSFFTFGTLKSV--GLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAG 251
Query: 198 AISQTLINPMEVLKTRLTLRRT-GQYKGLL---DCARQILQREGTR-ALYRGYLPNMLGI 252
AI+QT+ P +V + R+ L +++ L D + + G R LYRG N +
Sbjct: 252 AIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRC 311
Query: 253 IPYACTDLAVYEMLQCFW 270
IP YE+++ F+
Sbjct: 312 IPSQAVAFTTYELMKQFF 329
Score = 42.7 bits (99), Expect = 5e-04
Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 12/130 (9%)
Query: 52 YAFGHMHDNNLEHLPSQQVLDTGEQLMVPVEVLEVDNKEALWKFLLSGAMAGAVSRTGTA 111
+ FG + L H P+ + + V V V+ LL G +AGA+++T +
Sbjct: 208 FTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVN--------LLCGGVAGAIAQTISY 259
Query: 112 PLDRAKVYMQVYSSKTNFTNLLGGLQSMV----QEGGFRSLWRGNGINVLKIAPEYAIKF 167
P D + MQ+ + F L +M G + L+RG +N ++ P A+ F
Sbjct: 260 PFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAF 319
Query: 168 SVFEQCKNYF 177
+ +E K +F
Sbjct: 320 TTYELMKQFF 329
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 118 bits (296), Expect = 7e-27
Identities = 84/280 (30%), Positives = 138/280 (49%), Gaps = 12/280 (4%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGIN 155
LL +AG +S + TAPL+ A V QV + + + + G R+LW+GN +
Sbjct: 16 LLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVA 75
Query: 156 VLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLT 215
L++ P A++ + + + F G ++AGSLA +S + P +++KTRL
Sbjct: 76 CLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLI 135
Query: 216 LRR--TGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKS 273
++ Y+GLL I Q+EG ALYRG ++G +P++ L VY L+ W
Sbjct: 136 MQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGP 195
Query: 274 GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV----EGSNPTMRGVL-- 327
P + ++V L+ Q S+P V+ +MQAQ G + G +
Sbjct: 196 RDQFSLPQ---NFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDC 252
Query: 328 -QRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
++I+ QG LGL+ G+T LLK++P GI + +E K+
Sbjct: 253 FRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
Score = 73.6 bits (179), Expect = 3e-13
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 10/173 (5%)
Query: 93 WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYS-SKTNFTNLLGGLQSMVQEGGFRSLWRG 151
W +++G++AG VS T P D K + + + + ++ LL ++ Q+ GF +L+RG
Sbjct: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
Query: 152 NGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLK 211
+ V+ P A V+ + + G + + LA A++QTL P E +K
Sbjct: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
Query: 212 TRLT-----LRRTG----QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPY 255
++ L +G + G +DC RQI++ +G L+ G N+L I+PY
Sbjct: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPY 279
Score = 72.8 bits (177), Expect = 5e-13
Identities = 55/183 (30%), Positives = 92/183 (50%), Gaps = 10/183 (5%)
Query: 188 ERLLAGSLAVAISQTLINPMEVLKTRLTLRRT-GQYKGLLDCARQILQREGTRALYRGYL 246
+RLL LA +S +L P+E+ + G +G ++ + EG RAL++G
Sbjct: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
Query: 247 PNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLV 306
L + P + LA Y F V D+G S S+ + +L+ + +YP L+
Sbjct: 74 VACLRLFPCSAVQLAAYRK---FVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLI 130
Query: 307 RTRMQAQDTVEGSNPTMRGVLQR---ILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEA 363
+TR+ Q+ +E P+ RG+L I Q+G+L LYRG++ T++ LP S +VY
Sbjct: 131 KTRLIMQNILE---PSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMN 187
Query: 364 MKK 366
++K
Sbjct: 188 LEK 190
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 110 bits (275), Expect = 2e-24
Identities = 86/292 (29%), Positives = 140/292 (47%), Gaps = 26/292 (8%)
Query: 94 KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSS------KTNFTNLLGGLQSMVQEGGFRS 147
K LL+G +A AVS+T AP++R K+ +QV +S + + ++ L + +E GF S
Sbjct: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
Query: 148 LWRGNGINVLKIAPEYAIKFSVFEQCKNYFC-GIQGSPPFQERLLA----GSLAVAISQT 202
WRGN NV++ P A+ F+ ++ K F G+ F LA G A A S
Sbjct: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
Query: 203 LINPMEVLKTRLTLR-----RTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYAC 257
++ P++ +TRL + Q+KGL DC +I + +G LY+G+ ++ GII Y
Sbjct: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
Query: 258 TDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVE 317
+ Y+ ++ K + LVS + TTC + SYP VR RM Q
Sbjct: 202 SYFGAYDTVKGLLPKPKK----TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQS--G 255
Query: 318 GSNPTMRGVLQ---RILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
+ +G L +I +G +RG +L+ G + V+Y+ +K+
Sbjct: 256 EAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRG-TGGALVLVLYDKIKE 306
Score = 56.2 bits (134), Expect = 5e-08
Identities = 50/206 (24%), Positives = 87/206 (42%), Gaps = 34/206 (16%)
Query: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLRRT-------GQYKGLLDCARQILQREGT 238
F + LLAG +A A+S+T + P+E +K L ++ + +YKG++DC +I + +G
Sbjct: 20 FGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGF 79
Query: 239 RALYRGYLPNMLGIIPYACTDLAVYEML-QCF------------WVKSGRDMGDPSGLVS 285
+ +RG L N++ P + A + Q F W + G +G S
Sbjct: 80 FSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATS 139
Query: 286 LSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGV---LQRILAQQGWLGLYRG 342
L V YPL RTR+ +G+ + +I G GLY+G
Sbjct: 140 LCVV-----------YPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQG 188
Query: 343 MTPTLLKVLPAGGISYVVYEAMKKTL 368
++ ++ + Y+ +K L
Sbjct: 189 FGVSVQGIIVYRASYFGAYDTVKGLL 214
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 107 bits (268), Expect = 1e-23
Identities = 84/299 (28%), Positives = 139/299 (46%), Gaps = 33/299 (11%)
Query: 93 WKFL---LSGAMAGAVSRTGTAPLDRAKVYMQVY------SSKTNFTNLLGGLQSMVQEG 143
W FL L+G +A AVS+T AP++R K+ +QV S++ + ++ + + +E
Sbjct: 6 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 65
Query: 144 GFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCG-----IQGSPPFQERLLAGSLAVA 198
GF S WRGN NV++ P A+ F+ ++ K F G Q F L +G A A
Sbjct: 66 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGA 125
Query: 199 ISQTLINPMEVLKTRLTL-----RRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGII 253
S + P++ +TRL ++ GL DC +I + +G R LY+G+ ++ GII
Sbjct: 126 TSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGII 185
Query: 254 PYACTDLAVYEMLQCFWVKSGRDMGDPSGL---VSLSSVTLSTTCGQMASYPLTLVRTRM 310
Y VY+ + + DP + VS T + SYP VR RM
Sbjct: 186 IYRAAYFGVYDTAKGM-------LPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRM 238
Query: 311 QAQDTVEGSNPTMRGVL---QRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Q +G++ G + ++I +G ++G +L+ + G V+Y+ +KK
Sbjct: 239 MMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGM-GGAFVLVLYDEIKK 296
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 107 bits (266), Expect = 2e-23
Identities = 79/284 (27%), Positives = 131/284 (46%), Gaps = 12/284 (4%)
Query: 93 WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN-------FTNLLGGLQSMVQEGGF 145
WK + G +A V+ GT P+D K +QV + + + L + +E G
Sbjct: 41 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGV 100
Query: 146 RSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLIN 205
+L+ G +L+ A IK +++ K F ++ G ++ IS T+ N
Sbjct: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIAN 160
Query: 206 PMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEM 265
P +VLK R+ + + ++ I Q+EGTR L+RG +P +L VY++
Sbjct: 161 PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220
Query: 266 LQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRG 325
+ + SG MGD +SS T G +AS P+ +VRTRM Q + G +G
Sbjct: 221 TKKHLILSGM-MGDTILTHFVSSFTCG-LAGALASNPVDVVRTRMMNQRAIVGHVDLYKG 278
Query: 326 VLQRIL---AQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
+ IL +G+ LY+G P L++ P I ++ YE +K+
Sbjct: 279 TVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Score = 68.9 bits (167), Expect = 7e-12
Identities = 51/185 (27%), Positives = 90/185 (48%), Gaps = 15/185 (8%)
Query: 193 GSLAVAISQTLINPMEVLKTRLTLRRTG--------QYKGLLDCARQILQREGTRALYRG 244
G LA +++ P+++ KTRL ++ +Y+G+ +I + EG ALY G
Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 106
Query: 245 YLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLT 304
P +L Y + +Y+ L+ +V+ + D + L+++ +S + P
Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLFVER---LEDETLLINMICGVVSGVISSTIANPTD 163
Query: 305 LVRTRMQAQDTV-EGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEA 363
+++ RMQAQ ++ +GS M G I Q+G GL+RG+ PT + G+ VY+
Sbjct: 164 VLKIRMQAQGSLFQGS---MIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220
Query: 364 MKKTL 368
KK L
Sbjct: 221 TKKHL 225
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 107 bits (266), Expect = 2e-23
Identities = 79/284 (27%), Positives = 131/284 (46%), Gaps = 12/284 (4%)
Query: 93 WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN-------FTNLLGGLQSMVQEGGF 145
WK + G +A V+ GT P+D K +QV + + + L + +E G
Sbjct: 38 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGV 97
Query: 146 RSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLIN 205
+L+ G +L+ A IK +++ K F ++ G ++ IS T+ N
Sbjct: 98 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIAN 157
Query: 206 PMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEM 265
P +VLK R+ + + ++ I Q+EGTR L+RG +P +L VY++
Sbjct: 158 PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 217
Query: 266 LQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRG 325
+ + SG MGD +SS T G +AS P+ +VRTRM Q + G +G
Sbjct: 218 TKKHLILSGM-MGDTILTHFVSSFTCG-LAGALASNPVDVVRTRMMNQRAIVGHVDLYKG 275
Query: 326 VLQRIL---AQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
+ IL +G+ LY+G P L++ P I ++ YE +K+
Sbjct: 276 TVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Score = 68.9 bits (167), Expect = 7e-12
Identities = 51/185 (27%), Positives = 90/185 (48%), Gaps = 15/185 (8%)
Query: 193 GSLAVAISQTLINPMEVLKTRLTLRRTG--------QYKGLLDCARQILQREGTRALYRG 244
G LA +++ P+++ KTRL ++ +Y+G+ +I + EG ALY G
Sbjct: 44 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 103
Query: 245 YLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLT 304
P +L Y + +Y+ L+ +V+ + D + L+++ +S + P
Sbjct: 104 IAPALLRQASYGTIKIGIYQSLKRLFVER---LEDETLLINMICGVVSGVISSTIANPTD 160
Query: 305 LVRTRMQAQDTV-EGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEA 363
+++ RMQAQ ++ +GS M G I Q+G GL+RG+ PT + G+ VY+
Sbjct: 161 VLKIRMQAQGSLFQGS---MIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 217
Query: 364 MKKTL 368
KK L
Sbjct: 218 TKKHL 222
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 106 bits (264), Expect = 4e-23
Identities = 82/297 (27%), Positives = 143/297 (48%), Gaps = 30/297 (10%)
Query: 94 KFLLSGAMAGAVSRTGTAPLDRAKVYMQV-YSSKT-----NFTNLLGGLQSMVQEGGFRS 147
K L+G +A A+S+T AP++R K+ +QV ++SK + ++ + + +E G S
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69
Query: 148 LWRGNGINVLKIAPEYAIKFSVFEQCKNYFCG-----IQGSPPFQERLLAGSLAVAISQT 202
WRGN NV++ P A+ F+ ++ K F G Q F L +G A A S
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129
Query: 203 LINPMEVLKTRLT--LRRTG---QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYAC 257
+ P++ +TRL + ++G +++GL DC +I + +G R LY+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRA 189
Query: 258 TDLAVYEMLQCFWVKSGRDMGDPSG---LVSLSSVTLSTTCGQMASYPLTLVRTRMQAQD 314
VY+ + + DP +VS T + SYP VR RM Q
Sbjct: 190 AYFGVYDTAKGM-------LPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQS 242
Query: 315 TVEGSNPTMRGVL---QRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
+G++ G + ++I +G ++G +L+ + G V+Y+ +KK +
Sbjct: 243 GRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGM-GGAFVLVLYDELKKVI 298
Score = 65.5 bits (158), Expect = 7e-11
Identities = 55/206 (26%), Positives = 90/206 (43%), Gaps = 34/206 (16%)
Query: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTG-------QYKGLLDCARQILQREGT 238
F + LAG +A AIS+T + P+E +K L ++ QYKG++DC +I + +G
Sbjct: 8 FAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGV 67
Query: 239 RALYRGYLPNMLGIIPYACTDLAVYEMLQ-----------CFWVKSGRDM--GDPSGLVS 285
+ +RG L N++ P + A + + FW ++ G +G S
Sbjct: 68 LSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATS 127
Query: 286 LSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGV---LQRILAQQGWLGLYRG 342
L V YPL RTR+ A G+ RG+ L +I G GLY+G
Sbjct: 128 LCFV-----------YPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQG 176
Query: 343 MTPTLLKVLPAGGISYVVYEAMKKTL 368
+ ++ ++ + VY+ K L
Sbjct: 177 FSVSVQGIIIYRAAYFGVYDTAKGML 202
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 103 bits (257), Expect = 2e-22
Identities = 81/285 (28%), Positives = 129/285 (45%), Gaps = 13/285 (4%)
Query: 93 WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN-------FTNLLGGLQSMVQEGGF 145
WK + G +A + GT P+D K +Q+ + + +L L + +E G
Sbjct: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
Query: 146 RSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLIN 205
++L+ G +L+ A IK ++ K F ++ G L+ IS T+ N
Sbjct: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
Query: 206 PMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEM 265
P +VLK R+ + G++ I Q+EGTR L++G +L VY++
Sbjct: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
Query: 266 LQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV-EGSNPTMR 324
+ + SG MGD LSS T G +AS P+ +VRTRM Q + +G
Sbjct: 186 TKKHLILSGL-MGDTVYTHFLSSFTCG-LAGALASNPVDVVRTRMMNQRVLRDGRCSGYT 243
Query: 325 GVLQRIL---AQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
G L +L +G+ LY+G P L++ P I +V YE +KK
Sbjct: 244 GTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Score = 68.2 bits (165), Expect = 1e-11
Identities = 54/187 (28%), Positives = 90/187 (48%), Gaps = 19/187 (10%)
Query: 193 GSLAVAISQTLINPMEVLKTRLTLR--------RTGQYKGLLDCARQILQREGTRALYRG 244
G LA ++ P+++ KTRL ++ + +Y+G+L +I + EG +ALY G
Sbjct: 12 GGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSG 71
Query: 245 YLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVS--LSSVTLSTTCGQMASYP 302
P ML Y + Y+ L+ +++ D P ++ LS V ST P
Sbjct: 72 IAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN-----P 126
Query: 303 LTLVRTRMQAQ-DTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVY 361
+++ RMQAQ +T++G M G I Q+G GL++G++ T + G+ VY
Sbjct: 127 TDVLKIRMQAQSNTIQGG---MIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVY 183
Query: 362 EAMKKTL 368
+ KK L
Sbjct: 184 DITKKHL 190
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 103 bits (257), Expect = 2e-22
Identities = 79/295 (26%), Positives = 138/295 (46%), Gaps = 30/295 (10%)
Query: 94 KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFT------NLLGGLQSMVQEGGFRS 147
K L+G +A A+S+T AP++R K+ +QV + T ++ + + +E G S
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
Query: 148 LWRGNGINVLKIAPEYAIKFSVFEQCKNYFCG-----IQGSPPFQERLLAGSLAVAISQT 202
WRGN NV++ P A+ F+ ++ K F G Q F L +G A A S
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
Query: 203 LINPMEVLKTRLT--LRRTG---QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYAC 257
+ P++ +TRL + + G +++GL DC +I + +G + LY+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
Query: 258 TDLAVYEMLQCFWVKSGRDMGDPSG---LVSLSSVTLSTTCGQMASYPLTLVRTRMQAQD 314
+Y+ + + DP ++S T + SYP VR RM Q
Sbjct: 190 AYFGIYDTAKGM-------LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQS 242
Query: 315 TVEGSNPTMRGVL---QRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
+G++ G L ++I +G ++G +L+ + G V+Y+ +KK
Sbjct: 243 GRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGM-GGAFVLVLYDEIKK 296
Score = 66.2 bits (160), Expect = 4e-11
Identities = 51/196 (26%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTG-------QYKGLLDCARQILQREGT 238
F + LAG +A AIS+T + P+E +K L ++ QYKG++DC +I + +G
Sbjct: 8 FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGV 67
Query: 239 RALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQM 298
+ +RG L N++ P + A + + ++ G D L ++ G
Sbjct: 68 LSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL-GGVDKRTQFWLYFAGNLASGGAAGAT 126
Query: 299 A---SYPLTLVRTRMQAQDTVEGSNPTMRGV---LQRILAQQGWLGLYRGMTPTLLKVLP 352
+ YPL RTR+ A G+ RG+ L +I G GLY+G ++ ++
Sbjct: 127 SLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIII 186
Query: 353 AGGISYVVYEAMKKTL 368
+ +Y+ K L
Sbjct: 187 YRAAYFGIYDTAKGML 202
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 100 bits (249), Expect = 2e-21
Identities = 75/282 (26%), Positives = 129/282 (45%), Gaps = 18/282 (6%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSS--KTNFTNLLGGLQSMVQEGGFRSLWRGNG 153
+ +GAMAG + + P+D K MQ S K +T++ G L+ +++ GF RG
Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
Query: 154 INVLKIAPEYAIKFSVFEQCKNYFCGI---QGSPPFQERLLAGSLAVAISQTLINPMEVL 210
+ ++ P +A+ F+ +E K + QG+ + AGS+A + ++NP EV+
Sbjct: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-AGSMATLLHDAVMNPAEVV 167
Query: 211 KTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFW 270
K RL + + Q++ + C R + + EG A YR Y + IP+ YE LQ
Sbjct: 168 KQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQ-EQ 225
Query: 271 VKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV-------EGSNPTM 323
V R S ++S L+ A+ PL + +T + Q+ V G M
Sbjct: 226 VNPHRTYNPQSHIISGG---LAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM 282
Query: 324 RGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMK 365
+ + G G ++G+ ++ +P+ IS+ VYE K
Sbjct: 283 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 80/185 (43%), Gaps = 12/185 (6%)
Query: 97 LSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINV 156
++G+MA + P + K +Q+Y+S+ + + ++++ + G + +R +
Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHR--SAISCIRTVWRTEGLGAFYRSYTTQL 205
Query: 157 LKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTL 216
P +I F +E + + P Q +++G LA A++ P++V KT L
Sbjct: 206 TMNIPFQSIHFITYEFLQEQVNPHRTYNP-QSHIISGGLAGALAAAATTPLDVCKTLLNT 264
Query: 217 RR---------TGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQ 267
+ +G+ G+ + R + Q G ++G ++ +P +VYE +
Sbjct: 265 QENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFK 324
Query: 268 CFWVK 272
F K
Sbjct: 325 YFLTK 329
Score = 42.7 bits (99), Expect = 5e-04
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 279 DPSGLVSLSSVTLSTTCGQMAS-------YPLTLVRTRMQA-QDTVEGSNPTMRGVLQRI 330
D L + +SV+ T G MA YP+ V+TRMQ+ + ++ G L++I
Sbjct: 35 DYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKI 94
Query: 331 LAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
+ +G+ RG+ ++ PA + + YE MK+TL
Sbjct: 95 MRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTL 132
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/180 (21%), Positives = 80/180 (44%), Gaps = 7/180 (3%)
Query: 190 LLAGSLAVAISQTLINPMEVLKTR---LTLRRTGQYKGLLDCARQILQREGTRALYRGYL 246
+ AG++A + +++ P++ +KTR L+ QY + ++I++ EG RG
Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
Query: 247 PNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLV 306
++G P A YE ++ G+ S L + + +++T P +V
Sbjct: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGN-SHLANGIAGSMATLLHDAVMNPAEVV 167
Query: 307 RTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
+ R+Q ++ S + ++ + +G YR T L +P I ++ YE +++
Sbjct: 168 KQRLQMYNSQHRSAISC---IRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQE 224
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 100 bits (249), Expect = 2e-21
Identities = 79/307 (25%), Positives = 136/307 (44%), Gaps = 37/307 (12%)
Query: 89 KEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQ--------VYSSKTNFTNLLGG----- 135
KE L +G G V T PL+ K +Q VY + + + G
Sbjct: 8 KENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRP 67
Query: 136 ----------LQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPP 185
L+S++++ G +SL+RG G N++ +AP A+ F+ + + K F GI
Sbjct: 68 TSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNS 127
Query: 186 FQERLLAGSLAVAISQTLINPMEVLKTRLTLR---RTGQYKGLLDCARQILQREGTRALY 242
+ + A I+ +L+NP+ ++KTR+ L R + L CAR + Q EG R Y
Sbjct: 128 NIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFY 187
Query: 243 RGYLPNMLGIIPYACTDLAVYEMLQCFWVK-------SGRDMGDPSGLVSLSSVTLSTTC 295
RG + G I A+YE L+ + + +G + S +++ LS C
Sbjct: 188 RGLTASYAG-ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGC 246
Query: 296 GQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGG 355
+YP ++RTR++ + T + + + ++G+L YRG+ L++ +P
Sbjct: 247 ASCIAYPHEVIRTRLREEGT---KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTA 303
Query: 356 ISYVVYE 362
I YE
Sbjct: 304 IVLSTYE 310
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/208 (26%), Positives = 86/208 (41%), Gaps = 37/208 (17%)
Query: 190 LLAGSLAVAISQTLINPMEVLKTRLT------------------------LRRTGQYKGL 225
L AG + P+EV+KTRL +R T GL
Sbjct: 15 LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGL 74
Query: 226 LDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVY----EMLQCFWVKSGRDMGDPS 281
+ IL++EG ++L+RG PN++G+ P A Y E +V + S
Sbjct: 75 FQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPN-------S 127
Query: 282 GLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQ-QGWLGLY 340
+V + S + P+ +V+TRMQ + V GS R + Q +G G Y
Sbjct: 128 NIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFY 187
Query: 341 RGMTPTLLKVLPAGGISYVVYEAMKKTL 368
RG+T + + I + +YE++KK L
Sbjct: 188 RGLTASYAGISET-IICFAIYESLKKYL 214
Score = 52.8 bits (125), Expect = 5e-07
Identities = 47/184 (25%), Positives = 79/184 (42%), Gaps = 16/184 (8%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQS---MVQEGGFRSLWRGN 152
+ S A ++ + P+ K MQ+ K + + LQ + Q G R +RG
Sbjct: 132 IFSAGSAAFITNSLMNPIWMVKTRMQL-EQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
Query: 153 GINVLKIAPEYAIKFSVFEQCKNYFCGI----------QGSPPFQERLLAGSLAVAISQT 202
+ I+ E I F+++E K Y + S F + A +L+ +
Sbjct: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
Query: 203 LINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAV 262
+ P EV++TRL T +YK + AR + + EG A YRG ++ IP L+
Sbjct: 250 IAYPHEVIRTRLREEGT-KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLST 308
Query: 263 YEML 266
YE++
Sbjct: 309 YELI 312
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 98.2 bits (243), Expect = 1e-20
Identities = 79/298 (26%), Positives = 134/298 (44%), Gaps = 35/298 (11%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQ-----VYSSKTNFTNLLGG-------------LQ 137
L +G G V T PL+ K +Q +Y S+ + G L+
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 138 SMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAV 197
++++ G RSL+RG G N++ +AP AI F+ + CK + Q +++ ++A
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 198 AISQTLINPMEVLKTRLTL--RRTGQYK-GLLDCARQILQREGTRALYRGYLPNMLGIIP 254
+ T NP+ ++KTRL L R G+ + G +C R++ Q +G + YRG + G I
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG-IS 188
Query: 255 YACTDLAVYEML--QCFWVKSGRDMGDPSGLVSLSS--------VTLSTTCGQMASYPLT 304
+YE + + K+ M + V +S S TC +YP
Sbjct: 189 ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHE 248
Query: 305 LVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYE 362
+VRTR++ + T S L ++ ++G+ LYRG+T L++ +P I YE
Sbjct: 249 VVRTRLREEGTKYRS---FFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 303
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/187 (24%), Positives = 83/187 (44%), Gaps = 19/187 (10%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQ---SMVQEGGFRSLWRGN 152
++S AMAG + T T P+ K +Q+ ++ +G + + Q G + +RG
Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQL-DARNRGERRMGAFECVRKVYQTDGLKGFYRGM 180
Query: 153 GINVLKIAPEYAIKFSVFEQCKNYFC-------------GIQGSPPFQERLLAGSLAVAI 199
+ I+ E I F ++E K ++ + F +LA + +
Sbjct: 181 SASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTC 239
Query: 200 SQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTD 259
+ T+ P EV++TRL T +Y+ ++Q EG +LYRG +++ IP
Sbjct: 240 ATTIAYPHEVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIM 298
Query: 260 LAVYEML 266
+A YE++
Sbjct: 299 MATYELV 305
Score = 37.7 bits (86), Expect = 0.017
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 17/109 (15%)
Query: 277 MGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV----EGSNPTMRGV------ 326
M LV L + T G + + PL +V+TR+Q+ E TM G
Sbjct: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
Query: 327 -------LQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
L+ IL ++G L+RG+ P L+ V P+ I + Y K+ L
Sbjct: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL 109
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 97.4 bits (241), Expect = 2e-20
Identities = 68/248 (27%), Positives = 122/248 (49%), Gaps = 11/248 (4%)
Query: 123 YSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQG 182
+ T FT + +V+ G R+LW G ++ P AI F+ ++Q K + CG
Sbjct: 90 FQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL 149
Query: 183 SPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALY 242
+ ++AG+LA + T+I+P+E+++T+L + Y+ L C R + + G R+L+
Sbjct: 150 TSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLW 208
Query: 243 RGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYP 302
G+ P L +P++ YE+++ W+ R S +S + +S T + + P
Sbjct: 209 LGWGPTALRDVPFSALYWFNYELVKS-WLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLP 267
Query: 303 LTLVRTRMQ----AQDTVEGSNP----TMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAG 354
+V+T+ Q A + V NP + +L+RI A+ G GL+ G P ++K P+
Sbjct: 268 FDVVKTQRQVALGAMEAVR-VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSC 326
Query: 355 GISYVVYE 362
I YE
Sbjct: 327 AIMISTYE 334
Score = 61.2 bits (147), Expect = 1e-09
Identities = 50/203 (24%), Positives = 97/203 (47%), Gaps = 21/203 (10%)
Query: 91 ALWKFLLSGAMAGAVSRTGT----APLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFR 146
AL L + +AGA++R GT +PL+ + +Q + ++ L +++ V +GG+R
Sbjct: 148 ALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQ--AQHVSYRELGACVRTAVAQGGWR 205
Query: 147 SLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERL----LAGSLAVAISQT 202
SLW G G L+ P A+ + +E K++ G + P Q + +AG ++ ++
Sbjct: 206 SLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFR--PKDQTSVGMSFVAGGISGTVAAV 263
Query: 203 LINPMEVLKTRLTLRRTGQYKGLLD---------CARQILQREGTRALYRGYLPNMLGII 253
L P +V+KT+ + ++ R+I GT+ L+ G+LP ++
Sbjct: 264 LTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAA 323
Query: 254 PYACTDLAVYEMLQCFWVKSGRD 276
P ++ YE + F+ + +D
Sbjct: 324 PSCAIMISTYEFGKSFFQRLNQD 346
Score = 56.6 bits (135), Expect = 3e-08
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 16/153 (10%)
Query: 221 QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSG--RDMG 278
++ G +D +I++ EGTR L+ G ++ +P Y+ L+ F D+
Sbjct: 95 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLY 154
Query: 279 DP---SGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQG 335
P L L +VT+ + PL L+RT++QAQ S + ++ +AQ G
Sbjct: 155 APMVAGALARLGTVTVIS--------PLELMRTKLQAQHV---SYRELGACVRTAVAQGG 203
Query: 336 WLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
W L+ G PT L+ +P + + YE +K L
Sbjct: 204 WRSLWLGWGPTALRDVPFSALYWFNYELVKSWL 236
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 97.4 bits (241), Expect = 2e-20
Identities = 68/248 (27%), Positives = 122/248 (49%), Gaps = 11/248 (4%)
Query: 123 YSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQG 182
+ T FT + +V+ G R+LW G ++ P AI F+ ++Q K + CG
Sbjct: 98 FQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL 157
Query: 183 SPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALY 242
+ ++AG+LA + T+I+P+E+++T+L + Y+ L C R + + G R+L+
Sbjct: 158 TSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLW 216
Query: 243 RGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYP 302
G+ P L +P++ YE+++ W+ R S +S + +S T + + P
Sbjct: 217 LGWGPTALRDVPFSALYWFNYELVKS-WLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLP 275
Query: 303 LTLVRTRMQ----AQDTVEGSNP----TMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAG 354
+V+T+ Q A + V NP + +L+RI A+ G GL+ G P ++K P+
Sbjct: 276 FDVVKTQRQVALGAMEAVR-VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSC 334
Query: 355 GISYVVYE 362
I YE
Sbjct: 335 AIMISTYE 342
Score = 61.2 bits (147), Expect = 1e-09
Identities = 50/203 (24%), Positives = 97/203 (47%), Gaps = 21/203 (10%)
Query: 91 ALWKFLLSGAMAGAVSRTGT----APLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFR 146
AL L + +AGA++R GT +PL+ + +Q + ++ L +++ V +GG+R
Sbjct: 156 ALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQ--AQHVSYRELGACVRTAVAQGGWR 213
Query: 147 SLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERL----LAGSLAVAISQT 202
SLW G G L+ P A+ + +E K++ G + P Q + +AG ++ ++
Sbjct: 214 SLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFR--PKDQTSVGMSFVAGGISGTVAAV 271
Query: 203 LINPMEVLKTRLTLRRTGQYKGLLD---------CARQILQREGTRALYRGYLPNMLGII 253
L P +V+KT+ + ++ R+I GT+ L+ G+LP ++
Sbjct: 272 LTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAA 331
Query: 254 PYACTDLAVYEMLQCFWVKSGRD 276
P ++ YE + F+ + +D
Sbjct: 332 PSCAIMISTYEFGKSFFQRLNQD 354
Score = 56.6 bits (135), Expect = 3e-08
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 16/153 (10%)
Query: 221 QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSG--RDMG 278
++ G +D +I++ EGTR L+ G ++ +P Y+ L+ F D+
Sbjct: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLY 162
Query: 279 DP---SGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQG 335
P L L +VT+ + PL L+RT++QAQ S + ++ +AQ G
Sbjct: 163 APMVAGALARLGTVTVIS--------PLELMRTKLQAQHV---SYRELGACVRTAVAQGG 211
Query: 336 WLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
W L+ G PT L+ +P + + YE +K L
Sbjct: 212 WRSLWLGWGPTALRDVPFSALYWFNYELVKSWL 244
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 96.7 bits (239), Expect = 3e-20
Identities = 76/280 (27%), Positives = 131/280 (46%), Gaps = 17/280 (6%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSS---KTNFTNLLGGLQSMVQEGGFRSLWRGN 152
L++G G +S PLD K+ V + + +L L ++ + G R L++G
Sbjct: 26 LIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGV 85
Query: 153 GINVLKIAPEYAIKFSVFEQCKNYFC-GIQGSPPFQERLLAGSLAVAISQTLINPMEVLK 211
N+ + + F + K+Y G E L++ + A A++ + NP+ V K
Sbjct: 86 TPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTK 145
Query: 212 TRLTLRRTG-------QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYE 264
TRL L+ QYKG+ D +I + EG R LY+G++P + G + YE
Sbjct: 146 TRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFMAYE 204
Query: 265 MLQCFWVKSGRDMGDP--SGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPT 322
+L+ + + + + S + +S LS A+YP +VR R+Q Q
Sbjct: 205 LLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG--- 261
Query: 323 MRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYE 362
+ V+ + ++G G Y+G+ P L++V PA I++VVYE
Sbjct: 262 VIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYE 301
Score = 57.8 bits (138), Expect = 2e-08
Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 14/188 (7%)
Query: 188 ERLLAGSLAVAISQTLINPMEVLKTRLT----LRRTGQYKGLLDCARQILQREGTRALYR 243
E L+AG +S ++P++++K R L +Y G+L C I + +G R LY+
Sbjct: 24 ENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQ 83
Query: 244 GYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSG-LVSLSSVTLSTTCGQMASYP 302
G PN+ G Y ++ + + + + + LVS + T C + P
Sbjct: 84 GVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLC---ITNP 140
Query: 303 LTLVRTRMQAQDTVEGSNP-----TMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGIS 357
L + +TR+ Q ++P M L +I +G GLY+G P L G +
Sbjct: 141 LWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQ 199
Query: 358 YVVYEAMK 365
++ YE +K
Sbjct: 200 FMAYELLK 207
Score = 50.8 bits (120), Expect = 2e-06
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 13/187 (6%)
Query: 94 KFLLSGAMAGAVSRTGTAPL--DRAKVYMQ----VYSSKTNFTNLLGGLQSMVQEGGFRS 147
++L+S A AGA++ T PL + ++ +Q V S + + L + + G R
Sbjct: 122 EYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRG 181
Query: 148 LWRGNGINVLKIAPEYAIKFSVFEQCK-NYFCGIQGSPPFQ----ERLLAGSLAVAISQT 202
L++G + L A++F +E K Y I P Q E + +L+ +
Sbjct: 182 LYKGF-VPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVA 240
Query: 203 LINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAV 262
P +V++ RL + Y G++D + ++EG Y+G PN++ + P C V
Sbjct: 241 ATYPYQVVRARLQDQHMF-YSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVV 299
Query: 263 YEMLQCF 269
YE + F
Sbjct: 300 YENVSHF 306
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 94.4 bits (233), Expect = 1e-19
Identities = 79/298 (26%), Positives = 134/298 (44%), Gaps = 36/298 (12%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQ-----VYSSKTNFTNLLGG-------------LQ 137
L +G G V T PL+ K +Q +Y S+ + G L+
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 138 SMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAV 197
++++ G RSL+RG G N++ +AP AI F+ + CK + Q +++ ++A
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 198 AISQTLINPMEVLKTRLTL--RRTGQYK-GLLDCARQILQREGTRALYRGYLPNMLGIIP 254
+ T NP+ ++KTRL L R G+ + G +C R++ Q +G + YRG + G I
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG-IS 188
Query: 255 YACTDLAVYEML--QCFWVKSGRDMGDPSGLVSLSS--------VTLSTTCGQMASYPLT 304
+YE + + K+ M + V +S S TC +YP
Sbjct: 189 ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-H 247
Query: 305 LVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYE 362
+VRTR++ + T S L ++ ++G+ LYRG+T L++ +P I YE
Sbjct: 248 VVRTRLREEGTKYRS---FFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
Score = 49.3 bits (116), Expect = 6e-06
Identities = 44/187 (23%), Positives = 82/187 (43%), Gaps = 20/187 (10%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQ---SMVQEGGFRSLWRGN 152
++S AMAG + T T P+ K +Q+ ++ +G + + Q G + +RG
Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQL-DARNRGERRMGAFECVRKVYQTDGLKGFYRGM 180
Query: 153 GINVLKIAPEYAIKFSVFEQCKNYFC-------------GIQGSPPFQERLLAGSLAVAI 199
+ I+ E I F ++E K ++ + F +LA + +
Sbjct: 181 SASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTC 239
Query: 200 SQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTD 259
+ T+ P V++TRL T +Y+ ++Q EG +LYRG +++ IP
Sbjct: 240 ATTIAYP-HVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIM 297
Query: 260 LAVYEML 266
+A YE++
Sbjct: 298 MATYELV 304
Score = 37.7 bits (86), Expect = 0.017
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 17/109 (15%)
Query: 277 MGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV----EGSNPTMRGV------ 326
M LV L + T G + + PL +V+TR+Q+ E TM G
Sbjct: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
Query: 327 -------LQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
L+ IL ++G L+RG+ P L+ V P+ I + Y K+ L
Sbjct: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL 109
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 89.0 bits (219), Expect = 6e-18
Identities = 68/285 (23%), Positives = 134/285 (47%), Gaps = 17/285 (5%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVY-----SSKTNFTNLLGGLQSMVQEGGFRSLWR 150
L S +A ++ T PLD AKV +QV SS + +LG + ++V+ G L+
Sbjct: 17 LFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYS 76
Query: 151 GNGINVLKIAPEYAIKFSVFEQCKNYF-CGIQGSPPFQERLLAGSLAVAISQTLINPMEV 209
G + + +++ +++ + + G + +P ++LAG ++ + P EV
Sbjct: 77 GLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEV 136
Query: 210 LKTRLTLRR-----TGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYE 264
+K RL + +Y G + R I EG L++G PN++ + CT+L Y+
Sbjct: 137 VKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYD 196
Query: 265 MLQCFWVKSGRDMGD-PSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTM 323
+++ +VK+ D P LV S ++ C S P+ +V+TR ++ G ++
Sbjct: 197 LMKEAFVKNNILADDVPCHLV---SALIAGFCATAMSSPVDVVKTRF--INSPPGQYKSV 251
Query: 324 RGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
++ +G ++G+ P+ L++ I +V +E +K+ L
Sbjct: 252 PNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKREL 296
Score = 64.3 bits (155), Expect = 2e-10
Identities = 50/195 (25%), Positives = 90/195 (46%), Gaps = 17/195 (8%)
Query: 184 PPFQERLLAGSLAVAISQTLINPMEVLKTRLTLR------RTGQYKGLLDCARQILQREG 237
P +L + +A ++ + P++ K RL ++ +YKG+L +++ EG
Sbjct: 11 PTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEG 70
Query: 238 TRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQ 297
LY G + I A + +Y+ +Q F + +G++ G S + T G
Sbjct: 71 RMKLYSGLPAGLQRQISSASLRIGLYDTVQEF-LTAGKETAPSLG----SKILAGLTTGG 125
Query: 298 MASY---PLTLVRTRMQAQDTVEGSNPTMRGVLQ--RILAQ-QGWLGLYRGMTPTLLKVL 351
+A + P +V+ R+QAQ + G P G RI+A +G GL++G TP L++ +
Sbjct: 126 VAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSV 185
Query: 352 PAGGISYVVYEAMKK 366
V Y+ MK+
Sbjct: 186 IINCTELVTYDLMKE 200
Score = 57.4 bits (137), Expect = 2e-08
Identities = 47/191 (24%), Positives = 82/191 (42%), Gaps = 13/191 (6%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSS----KTNFTNLLGGLQSMVQEGGFRSLWRG 151
+L+G G V+ P + KV +Q S K +T + + G LW+G
Sbjct: 117 ILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKG 176
Query: 152 NGINVLKIAPEYAIKFSVFEQCKNYFCG---IQGSPPFQ--ERLLAGSLAVAISQTLINP 206
N+++ + ++ K F + P L+AG A A+S +P
Sbjct: 177 TTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMS----SP 232
Query: 207 MEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEML 266
++V+KTR GQYK + +CA ++ EG A ++G +P+ L + + +E L
Sbjct: 233 VDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQL 292
Query: 267 QCFWVKSGRDM 277
+ KS + M
Sbjct: 293 KRELSKSRQTM 303
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 88.2 bits (217), Expect = 1e-17
Identities = 61/247 (24%), Positives = 123/247 (49%), Gaps = 9/247 (3%)
Query: 123 YSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQG 182
Y NF L +++ G +SLW G ++ P I F+ ++Q G
Sbjct: 78 YKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLG 137
Query: 183 SPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALY 242
++AG +A + T+I+P+E+++T++ ++ Y L + + +G +L+
Sbjct: 138 ENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFS-YVELHRFVSKKVSEDGWISLW 196
Query: 243 RGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYP 302
RG+ P +L +P++ YE+L+ W+ + +P+ +++ +S LS + +A+ P
Sbjct: 197 RGWAPTVLRDVPFSAMYWYNYEILKK-WLCEKSGLYEPTFMINFTSGALSGSFAAVATLP 255
Query: 303 LTLVRTRMQAQ----DTVEGSNPTMRG---VLQRILAQQGWLGLYRGMTPTLLKVLPAGG 355
+V+T+ Q Q ++ + S P +++ I+A+ G+ GL+ G+ P L+K+ PA
Sbjct: 256 FDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACA 315
Query: 356 ISYVVYE 362
I YE
Sbjct: 316 IMISTYE 322
Score = 64.3 bits (155), Expect = 2e-10
Identities = 37/156 (23%), Positives = 78/156 (50%), Gaps = 6/156 (3%)
Query: 213 RLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVK 272
+L ++ G ++G LD +I++ EG ++L+ G P ++ +P Y+ L
Sbjct: 75 KLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRS 134
Query: 273 SGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILA 332
+G+ + + + ++ PL L+RT+MQ++ + S + + + ++
Sbjct: 135 K---LGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSK---KFSYVELHRFVSKKVS 188
Query: 333 QQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
+ GW+ L+RG PT+L+ +P + + YE +KK L
Sbjct: 189 EDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL 224
Score = 57.4 bits (137), Expect = 2e-08
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 17/187 (9%)
Query: 101 MAGAVSRTGT----APLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINV 156
+AG V+R G +PL+ + MQ S K ++ L + V E G+ SLWRG V
Sbjct: 146 VAGIVARFGAVTVISPLELIRTKMQ--SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTV 203
Query: 157 LKIAPEYAIKFSVFEQCKNYFCGIQG--SPPFQERLLAGSLAVAISQTLINPMEVLKTRL 214
L+ P A+ + +E K + C G P F +G+L+ + + P +V+KT+
Sbjct: 204 LRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQK 263
Query: 215 TLR---------RTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEM 265
+ + + I+ + G L+ G +P ++ I P ++ YE
Sbjct: 264 QTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEF 323
Query: 266 LQCFWVK 272
+ F+ K
Sbjct: 324 GKAFFQK 330
Score = 35.4 bits (80), Expect = 0.083
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 8/88 (9%)
Query: 98 SGAMAGAVSRTGTAPLDRAKVYMQVY-----SSKTNFTNLLGG---LQSMVQEGGFRSLW 149
SGA++G+ + T P D K Q S K + + ++++V + GF L+
Sbjct: 241 SGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLF 300
Query: 150 RGNGINVLKIAPEYAIKFSVFEQCKNYF 177
G ++KIAP AI S +E K +F
Sbjct: 301 SGLIPRLIKIAPACAIMISTYEFGKAFF 328
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 87.8 bits (216), Expect = 1e-17
Identities = 80/318 (25%), Positives = 137/318 (43%), Gaps = 29/318 (9%)
Query: 61 NLEHLPSQQVLDTGEQLMVPVEVLEVDNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYM 120
NL L QQ G + + + E+ ++F L G++AGAV T P+D K M
Sbjct: 303 NLAELQRQQSPGLGRPIWLQIA-------ESAYRFTL-GSVAGAVGATAVYPIDLVKTRM 354
Query: 121 QVYSSKTN------FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCK 174
Q + + N + +++ GF L+RG ++ +APE AIK +V + +
Sbjct: 355 QNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVR 414
Query: 175 NYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLR---RTGQYKGLLDCARQ 231
+ F GS P +LAG A NP+E++K RL + TG L+ R
Sbjct: 415 DKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRD 474
Query: 232 ILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTL 291
+ G LY+G L IP++ VY + +G GL L++ +
Sbjct: 475 L----GIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVG---GLNLLAAGAM 527
Query: 292 STTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVL---QRILAQQGWLGLYRGMTPTLL 348
+ P +++TR+Q T GV+ ++IL ++G ++G +
Sbjct: 528 AGVPAASLVTPADVIKTRLQV--AARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVF 585
Query: 349 KVLPAGGISYVVYEAMKK 366
+ P G++ V YE +++
Sbjct: 586 RSSPQFGVTLVTYELLQR 603
Score = 42.7 bits (99), Expect = 5e-04
Identities = 20/84 (23%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYS--SKTNFTNLLGGLQSMVQEGGFRSLWRGNG 153
L +GAMAG + + P D K +QV + +T ++ ++ + +++E G + W+G
Sbjct: 522 LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTA 581
Query: 154 INVLKIAPEYAIKFSVFEQCKNYF 177
V + +P++ + +E + +F
Sbjct: 582 ARVFRSSPQFGVTLVTYELLQRWF 605
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,814,713
Number of Sequences: 37866
Number of extensions: 815901
Number of successful extensions: 14645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 281
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 10024
Number of HSP's gapped (non-prelim): 3057
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.