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Search of human proteins with 14916455
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14916455 protein serine kinase H2 [Homo sapiens]
(385 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14916455 protein serine kinase H2 [Homo sapiens] 770 0.0
gi|27901803 protein serine kinase H1 [Homo sapiens] 476 e-134
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 254 7e-68
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 254 7e-68
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 251 1e-66
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 243 3e-64
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 237 2e-62
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 235 4e-62
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 223 2e-58
gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens] 212 5e-55
gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 206 2e-53
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 202 3e-52
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 202 3e-52
gi|149589021 doublecortin-like kinase 3 [Homo sapiens] 187 1e-47
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 186 4e-47
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 186 4e-47
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 186 4e-47
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 186 4e-47
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 186 4e-47
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 186 4e-47
gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is... 186 4e-47
gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is... 186 4e-47
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 183 3e-46
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 183 3e-46
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 183 3e-46
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 183 3e-46
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 183 3e-46
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 182 3e-46
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 182 3e-46
gi|4557511 death-associated protein kinase 3 [Homo sapiens] 182 3e-46
>gi|14916455 protein serine kinase H2 [Homo sapiens]
Length = 385
Score = 770 bits (1988), Expect = 0.0
Identities = 385/385 (100%), Positives = 385/385 (100%)
Query: 1 MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVL 60
MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVL
Sbjct: 1 MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVL 60
Query: 61 ARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYI 120
ARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYI
Sbjct: 61 ARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYI 120
Query: 121 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 180
VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT
Sbjct: 121 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 180
Query: 181 HRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 240
HRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT
Sbjct: 181 HRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 240
Query: 241 SAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKL 300
SAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKL
Sbjct: 241 SAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKL 300
Query: 301 LILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSH 360
LILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSH
Sbjct: 301 LILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSH 360
Query: 361 YSHKSRHMWSKRNLRIVESPLSALL 385
YSHKSRHMWSKRNLRIVESPLSALL
Sbjct: 361 YSHKSRHMWSKRNLRIVESPLSALL 385
>gi|27901803 protein serine kinase H1 [Homo sapiens]
Length = 424
Score = 476 bits (1225), Expect = e-134
Identities = 252/414 (60%), Positives = 311/414 (75%), Gaps = 41/414 (9%)
Query: 1 MGCGASRKVVPGPPA------------------------LAWAKHEGQNQAGVGGAG--- 33
MGCG S KV+P PP + G +AG A
Sbjct: 1 MGCGTS-KVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYA 59
Query: 34 ---PGPEAA------AQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKT 84
PGP A ++ +R +VA++RAKFDPRV A+YDIKALIG GSFSRVVRVE +
Sbjct: 60 HPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRA 119
Query: 85 TKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGE 144
T++P+AIK++ET+ REGRE C SEL VLRRV H I+QL+E+FET+++VYMVMELATGGE
Sbjct: 120 TRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGE 179
Query: 145 LFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITD 204
LFDR+IA+GSFTERDA R+LQMV DG+RYLHAL ITHR+LKPENLLYYHPG +SKI+ITD
Sbjct: 180 LFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITD 239
Query: 205 FGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDD 264
FGLA + KK D MKT CGTPEYIAPEVL+RKPYT++VDMWALGVI Y LLSG +PF+D
Sbjct: 240 FGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFED 299
Query: 265 ESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMA 324
+++TRLYR+IL+GKY+Y+GEPWPS+S+LAKDFID+LL ++ G RM+A QAL HPWV++MA
Sbjct: 300 DNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMA 359
Query: 325 AGSSMKNLQRAISRNLMQRASPHSQSPGSAQ---SSKSHYSHKSRHMWSKRNLR 375
A SSMKNL R+IS+NL++RAS QS SAQ SS+S S+KSR + +R LR
Sbjct: 360 ASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRV-RERELR 412
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 254 bits (650), Expect = 7e-68
Identities = 127/279 (45%), Positives = 188/279 (67%), Gaps = 5/279 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIV 121
++ K +GTG+FS VV E+K T K FA+K + + +G+E+ + +E++VLR++ H IV
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82
Query: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181
L +I+E+ + +Y+VM+L +GGELFDR++ +G +TE+DA +++ V D + YLH + I H
Sbjct: 83 ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVH 142
Query: 182 RNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTS 241
R+LKPENLLYY EESKI+I+DFGL+ K GD M T CGTP Y+APEVL +KPY+
Sbjct: 143 RDLKPENLLYYSQDEESKIMISDFGLSKMEGK-GD-VMSTACGTPGYVAPEVLAQKPYSK 200
Query: 242 AVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLL 301
AVD W++GVI Y LL G+ PF DE+ ++L+ +ILK +Y + W IS AKDFI L+
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 302 ILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNL 340
+ R + QA HPW+ A + KN+ ++S +
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALN--KNIHESVSAQI 297
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 254 bits (650), Expect = 7e-68
Identities = 127/279 (45%), Positives = 188/279 (67%), Gaps = 5/279 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIV 121
++ K +GTG+FS VV E+K T K FA+K + + +G+E+ + +E++VLR++ H IV
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82
Query: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181
L +I+E+ + +Y+VM+L +GGELFDR++ +G +TE+DA +++ V D + YLH + I H
Sbjct: 83 ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVH 142
Query: 182 RNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTS 241
R+LKPENLLYY EESKI+I+DFGL+ K GD M T CGTP Y+APEVL +KPY+
Sbjct: 143 RDLKPENLLYYSQDEESKIMISDFGLSKMEGK-GD-VMSTACGTPGYVAPEVLAQKPYSK 200
Query: 242 AVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLL 301
AVD W++GVI Y LL G+ PF DE+ ++L+ +ILK +Y + W IS AKDFI L+
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 302 ILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNL 340
+ R + QA HPW+ A + KN+ ++S +
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALN--KNIHESVSAQI 297
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 251 bits (640), Expect = 1e-66
Identities = 127/281 (45%), Positives = 185/281 (65%), Gaps = 9/281 (3%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIV 121
YD + ++GTG+FS V+ E K T+K AIK + EG+E + +E++VL ++ H IV
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIV 79
Query: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181
L +I+E+ +Y++M+L +GGELFDR++ +G +TERDA R++ V D ++YLH L I H
Sbjct: 80 ALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVH 139
Query: 182 RNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTS 241
R+LKPENLLYY E+SKI+I+DFGL S + + T CGTP Y+APEVL +KPY+
Sbjct: 140 RDLKPENLLYYSLDEDSKIMISDFGL--SKMEDPGSVLSTACGTPGYVAPEVLAQKPYSK 197
Query: 242 AVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLL 301
AVD W++GVI Y LL G+ PF DE+ +L+ +ILK +Y + W IS AKDFI L+
Sbjct: 198 AVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLM 257
Query: 302 ILEAGHRMSAGQALDHPWVITMAAGSSM--KNLQRAISRNL 340
+ R + QAL HPW+ AG + KN+ +++S +
Sbjct: 258 EKDPEKRFTCEQALQHPWI----AGDTALDKNIHQSVSEQI 294
>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform a [Homo sapiens]
Length = 426
Score = 243 bits (619), Expect = 3e-64
Identities = 140/351 (39%), Positives = 205/351 (58%), Gaps = 15/351 (4%)
Query: 4 GASRKVVPGP---PALAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVL 60
G S + GP PA + + +G+GG G P A +Q K +
Sbjct: 38 GDSHRWCKGPGAGPAGPQLREAARASSGLGGGGRHPSRIPAIA--LQDMLLLKKHTEDIS 95
Query: 61 ARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRY 119
+ Y+I+ +G+G+FS VV +++ + A+K + + G+EA V +E++VLRR+SH
Sbjct: 96 SVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPN 155
Query: 120 IVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQI 179
IV L ++ E+ +Y+ MEL TGGELFDR++ +GS+TE+DA ++ V + YLH+L I
Sbjct: 156 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 215
Query: 180 THRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPY 239
HR+LKPENLLY P E+SKI+++DFGL+ K + T CGTP Y+APE+L +KPY
Sbjct: 216 VHRDLKPENLLYATPFEDSKIMVSDFGLS---KIQAGNMLGTACGTPGYVAPELLEQKPY 272
Query: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
AVD+WALGVI+Y LL G+ PF DES L+ +IL+ Y + W IS AKDFI
Sbjct: 273 GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRH 332
Query: 300 LLILEAGHRMSAGQALDHPWVITMAA------GSSMKNLQRAISRNLMQRA 344
LL + R + QAL H W+ A GS + +++ +R +RA
Sbjct: 333 LLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRA 383
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 237 bits (604), Expect = 2e-62
Identities = 116/253 (45%), Positives = 169/253 (66%), Gaps = 3/253 (1%)
Query: 68 LIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIF 127
++G+G+FS V V+Q+ T K FA+K ++ + +E++VL+++ H IV L +I+
Sbjct: 28 VLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIY 87
Query: 128 ETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPE 187
E+ Y+VM+L +GGELFDR++ +G +TE+DA ++Q V ++YLH I HR+LKPE
Sbjct: 88 ESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPE 147
Query: 188 NLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWA 247
NLLY P E SKI+ITDFGL+ K + M T CGTP Y+APEVL +KPY+ AVD W+
Sbjct: 148 NLLYLTPEENSKIMITDFGLS---KMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWS 204
Query: 248 LGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGH 307
+GVITY LL G+ PF +E++++L+ KI +G Y + W IS AKDFI LL +
Sbjct: 205 IGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNE 264
Query: 308 RMSAGQALDHPWV 320
R + +AL HPW+
Sbjct: 265 RYTCEKALSHPWI 277
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 235 bits (600), Expect = 4e-62
Identities = 126/289 (43%), Positives = 183/289 (63%), Gaps = 10/289 (3%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIV 121
Y+I+ +G+G+FS VV +++ + A+K + + G+EA V +E++VLRR+SH IV
Sbjct: 32 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIV 91
Query: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181
L ++ E+ +Y+ MEL TGGELFDR++ +GS+TE+DA ++ V + YLH+L I H
Sbjct: 92 ALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVH 151
Query: 182 RNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTS 241
R+LKPENLLY P E+SKI+++DFGL+ K + T CGTP Y+APE+L +KPY
Sbjct: 152 RDLKPENLLYATPFEDSKIMVSDFGLS---KIQAGNMLGTACGTPGYVAPELLEQKPYGK 208
Query: 242 AVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLL 301
AVD+WALGVI+Y LL G+ PF DES L+ +IL+ Y + W IS AKDFI LL
Sbjct: 209 AVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLL 268
Query: 302 ILEAGHRMSAGQALDHPWVITMAA------GSSMKNLQRAISRNLMQRA 344
+ R + QAL H W+ A GS + +++ +R +RA
Sbjct: 269 ERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRA 317
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 223 bits (569), Expect = 2e-58
Identities = 129/318 (40%), Positives = 194/318 (61%), Gaps = 15/318 (4%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQ 122
+++++ +G G+ S V R +QK T+KP+A+KV+ ++ ++ +E+ VL R+SH I++
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVL--KKTVDKKIVRTEIGVLLRLSHPNIIK 103
Query: 123 LMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHR 182
L EIFET ++ +V+EL TGGELFDR++ +G ++ERDA ++ + + + YLH I HR
Sbjct: 104 LKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHR 163
Query: 183 NLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSA 242
+LKPENLLY P ++ + I DFGL S MKT+CGTP Y APE+L Y
Sbjct: 164 DLKPENLLYATPAPDAPLKIADFGL--SKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPE 221
Query: 243 VDMWALGVITYALLSGFLPFDDESQTR-LYRKILKGKYNYTGEPWPSISHLAKDFIDKLL 301
VDMW++G+ITY LL GF PF DE + ++R+IL +Y + W +S AKD + KL+
Sbjct: 222 VDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLI 281
Query: 302 ILEAGHRMSAGQALDHPWVITMAAG-----SSMKNLQRAISRNLMQ---RASPHSQSPGS 353
+L+ R++ QAL HPWV AA ++ K LQ +R ++ +A S GS
Sbjct: 282 VLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGS 341
Query: 354 AQSSKSHYSHKSRHMWSK 371
A S SH S + H S+
Sbjct: 342 A--SSSHGSIQESHKASR 357
>gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]
Length = 501
Score = 212 bits (539), Expect = 5e-55
Identities = 123/327 (37%), Positives = 187/327 (57%), Gaps = 30/327 (9%)
Query: 59 VLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETRE-REGREACVSELSVLRRVSH 117
V RYD+ +I T F + R + KTT K K + R+ R+ R+A +E+ +L+ V H
Sbjct: 20 VTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRKVRKAAKNEIGILKMVKH 79
Query: 118 RYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHAL 177
I+QL+++F T + ++ +ELATG E+FD ++ QG ++ERD +++ V + + YLH+L
Sbjct: 80 PNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSL 139
Query: 178 QITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRK 237
+I HRNLK ENL+YY+ + SKI+I+DF LA K + +K CGTPEY+APEV+ R+
Sbjct: 140 KIVHRNLKLENLVYYNRLKNSKIVISDFHLA----KLENGLIKEPCGTPEYLAPEVVGRQ 195
Query: 238 PYTSAVDMWALGVITYALLSGFLPFDDESQ--------TRLYRKILKGKYNYTGEPWPSI 289
Y VD WA+GVI Y LLSG PF +E + L+RKIL G Y + W I
Sbjct: 196 RYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDI 255
Query: 290 SHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSS----------MKNLQRA---- 335
S AKD + +L+ +E R++A +A+ H W+ AA KN RA
Sbjct: 256 SQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKK 315
Query: 336 ---ISRNLMQRASPHSQSPGSAQSSKS 359
++ + + +P S +AQS+ +
Sbjct: 316 AVRVTTLMKRLRAPEQSSTAAAQSASA 342
>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
Length = 729
Score = 206 bits (525), Expect = 2e-53
Identities = 114/292 (39%), Positives = 172/292 (58%), Gaps = 18/292 (6%)
Query: 33 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK 92
GPG E + + Q + RY + IG G+F+ V +++T + +A+K
Sbjct: 370 GPGEEVSEEGFQ----------IPATITERYKVGRTIGDGNFAVVKECVERSTAREYALK 419
Query: 93 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA 151
+++ + G+E + +E+S+LRRV H IV L+E + ++Y+VMEL GG+LFD + +
Sbjct: 420 IIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITS 479
Query: 152 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKIL-ITDFGLAYS 210
+TERDA +L +A I+YLH+L I HR++KPENLL Y + SK L + DFGLA
Sbjct: 480 TNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA-- 537
Query: 211 GKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPF--DDESQT 268
D + T+CGTP Y+APE++ Y VD+WA GVITY LL GF PF + Q
Sbjct: 538 --TIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQE 595
Query: 269 RLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
L+ +IL G+ ++ W ++S AK+ I +L+++ R SA Q L+HPWV
Sbjct: 596 VLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWV 647
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 202 bits (515), Expect = 3e-52
Identities = 114/288 (39%), Positives = 172/288 (59%), Gaps = 10/288 (3%)
Query: 59 VLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSH 117
+L +Y I +IG G+F+ V ++T K FA+K+++ + G+E + +E+S+LRRV H
Sbjct: 389 LLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKH 448
Query: 118 RYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHAL 177
I+ L+E ET ++++VMEL GG+LFD + + +TERD ++ +A+ +RYLH L
Sbjct: 449 PNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGL 508
Query: 178 QITHRNLKPENLLY-YHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLR 236
I HR++KPENLL +P + + DFGLA + + T+CGTP Y+APE++
Sbjct: 509 SIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA----TVVEGPLYTVCGTPTYVAPEIIAE 564
Query: 237 KPYTSAVDMWALGVITYALLSGFLPFDDES--QTRLYRKILKGKYNYTGEPWPSISHLAK 294
Y VD+WA GVITY LL GF PF E+ Q L+ +IL GK + W +I+ AK
Sbjct: 565 TGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 624
Query: 295 DFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQ 342
+ I ++L + R +AGQ L HPWV A S N+Q ++ L Q
Sbjct: 625 ELISQMLQVNVEARCTAGQILSHPWVSDDA--SQENNMQAEVTGKLKQ 670
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 202 bits (515), Expect = 3e-52
Identities = 114/288 (39%), Positives = 172/288 (59%), Gaps = 10/288 (3%)
Query: 59 VLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSH 117
+L +Y I +IG G+F+ V ++T K FA+K+++ + G+E + +E+S+LRRV H
Sbjct: 390 LLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKH 449
Query: 118 RYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHAL 177
I+ L+E ET ++++VMEL GG+LFD + + +TERD ++ +A+ +RYLH L
Sbjct: 450 PNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGL 509
Query: 178 QITHRNLKPENLLY-YHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLR 236
I HR++KPENLL +P + + DFGLA + + T+CGTP Y+APE++
Sbjct: 510 SIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA----TVVEGPLYTVCGTPTYVAPEIIAE 565
Query: 237 KPYTSAVDMWALGVITYALLSGFLPFDDES--QTRLYRKILKGKYNYTGEPWPSISHLAK 294
Y VD+WA GVITY LL GF PF E+ Q L+ +IL GK + W +I+ AK
Sbjct: 566 TGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 625
Query: 295 DFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQ 342
+ I ++L + R +AGQ L HPWV A S N+Q ++ L Q
Sbjct: 626 ELISQMLQVNVEARCTAGQILSHPWVSDDA--SQENNMQAEVTGKLKQ 671
>gi|149589021 doublecortin-like kinase 3 [Homo sapiens]
Length = 648
Score = 187 bits (476), Expect = 1e-47
Identities = 103/279 (36%), Positives = 164/279 (58%), Gaps = 9/279 (3%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIV 121
Y+ +IG G+F+ V + T++ +A+K+++ +G+E V SE+ +++ +SH IV
Sbjct: 356 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIV 415
Query: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181
+L E++ET+ ++Y+++E GG+LFD +I F E DA ++ + + ++H I H
Sbjct: 416 KLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVH 475
Query: 182 RNLKPENLLYYHPGEESKIL-ITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 240
R+LKPENLL ++S L + DFGLA K + T+CGTP Y+APE+L K Y
Sbjct: 476 RDLKPENLLVQRNEDKSTTLKLADFGLA----KHVVRPIFTVCGTPTYVAPEILSEKGYG 531
Query: 241 SAVDMWALGVITYALLSGFLPF--DDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFID 298
VDMWA GVI Y LL GF PF + Q L+ I G + + W +IS AKD +
Sbjct: 532 LEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVS 591
Query: 299 KLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAIS 337
+LL+++ R +A Q L HPW+ T +++K Q+ +S
Sbjct: 592 RLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKR-QKQVS 629
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 186 bits (471), Expect = 4e-47
Identities = 100/281 (35%), Positives = 156/281 (55%), Gaps = 3/281 (1%)
Query: 58 RVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRV 115
R Y + +G G+FS V R + T + +A K++ T++ R+ E + R +
Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL 68
Query: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLH 175
H IV+L + E Y+V +L TGGELF+ ++A+ ++E DA +Q + + + + H
Sbjct: 69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCH 128
Query: 176 ALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
I HR+LKPENLL + + + + DFGLA + GTP Y++PEVL
Sbjct: 129 LNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR 187
Query: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
+ PY VDMWA GVI Y LL G+ PF DE Q RLY++I G Y++ W +++ AKD
Sbjct: 188 KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 247
Query: 296 FIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
I+K+L + R++A +AL HPW+ + +SM + Q +
Sbjct: 248 LINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETV 288
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 186 bits (471), Expect = 4e-47
Identities = 100/281 (35%), Positives = 156/281 (55%), Gaps = 3/281 (1%)
Query: 58 RVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRV 115
R Y + +G G+FS V R + T + +A K++ T++ R+ E + R +
Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL 68
Query: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLH 175
H IV+L + E Y+V +L TGGELF+ ++A+ ++E DA +Q + + + + H
Sbjct: 69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCH 128
Query: 176 ALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
I HR+LKPENLL + + + + DFGLA + GTP Y++PEVL
Sbjct: 129 LNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR 187
Query: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
+ PY VDMWA GVI Y LL G+ PF DE Q RLY++I G Y++ W +++ AKD
Sbjct: 188 KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 247
Query: 296 FIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
I+K+L + R++A +AL HPW+ + +SM + Q +
Sbjct: 248 LINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETV 288
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 186 bits (471), Expect = 4e-47
Identities = 100/281 (35%), Positives = 156/281 (55%), Gaps = 3/281 (1%)
Query: 58 RVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRV 115
R Y + +G G+FS V R + T + +A K++ T++ R+ E + R +
Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL 68
Query: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLH 175
H IV+L + E Y+V +L TGGELF+ ++A+ ++E DA +Q + + + + H
Sbjct: 69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCH 128
Query: 176 ALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
I HR+LKPENLL + + + + DFGLA + GTP Y++PEVL
Sbjct: 129 LNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR 187
Query: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
+ PY VDMWA GVI Y LL G+ PF DE Q RLY++I G Y++ W +++ AKD
Sbjct: 188 KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 247
Query: 296 FIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
I+K+L + R++A +AL HPW+ + +SM + Q +
Sbjct: 248 LINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETV 288
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 186 bits (471), Expect = 4e-47
Identities = 100/281 (35%), Positives = 156/281 (55%), Gaps = 3/281 (1%)
Query: 58 RVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRV 115
R Y + +G G+FS V R + T + +A K++ T++ R+ E + R +
Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL 68
Query: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLH 175
H IV+L + E Y+V +L TGGELF+ ++A+ ++E DA +Q + + + + H
Sbjct: 69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCH 128
Query: 176 ALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
I HR+LKPENLL + + + + DFGLA + GTP Y++PEVL
Sbjct: 129 LNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR 187
Query: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
+ PY VDMWA GVI Y LL G+ PF DE Q RLY++I G Y++ W +++ AKD
Sbjct: 188 KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 247
Query: 296 FIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
I+K+L + R++A +AL HPW+ + +SM + Q +
Sbjct: 248 LINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETV 288
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 186 bits (471), Expect = 4e-47
Identities = 100/281 (35%), Positives = 156/281 (55%), Gaps = 3/281 (1%)
Query: 58 RVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRV 115
R Y + +G G+FS V R + T + +A K++ T++ R+ E + R +
Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL 68
Query: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLH 175
H IV+L + E Y+V +L TGGELF+ ++A+ ++E DA +Q + + + + H
Sbjct: 69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCH 128
Query: 176 ALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
I HR+LKPENLL + + + + DFGLA + GTP Y++PEVL
Sbjct: 129 LNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR 187
Query: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
+ PY VDMWA GVI Y LL G+ PF DE Q RLY++I G Y++ W +++ AKD
Sbjct: 188 KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 247
Query: 296 FIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
I+K+L + R++A +AL HPW+ + +SM + Q +
Sbjct: 248 LINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETV 288
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 186 bits (471), Expect = 4e-47
Identities = 100/281 (35%), Positives = 156/281 (55%), Gaps = 3/281 (1%)
Query: 58 RVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRV 115
R Y + +G G+FS V R + T + +A K++ T++ R+ E + R +
Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL 68
Query: 116 SHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLH 175
H IV+L + E Y+V +L TGGELF+ ++A+ ++E DA +Q + + + + H
Sbjct: 69 KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCH 128
Query: 176 ALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
I HR+LKPENLL + + + + DFGLA + GTP Y++PEVL
Sbjct: 129 LNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR 187
Query: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
+ PY VDMWA GVI Y LL G+ PF DE Q RLY++I G Y++ W +++ AKD
Sbjct: 188 KDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 247
Query: 296 FIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
I+K+L + R++A +AL HPW+ + +SM + Q +
Sbjct: 248 LINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETV 288
>gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2
isoform b [Homo sapiens]
Length = 741
Score = 186 bits (471), Expect = 4e-47
Identities = 101/264 (38%), Positives = 156/264 (59%), Gaps = 10/264 (3%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVS-HRYIV 121
Y+IK IG GS+S R K T +A+K+++ +R+ E E+ +L R H I+
Sbjct: 423 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE----EIEILLRYGQHPNII 478
Query: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181
L ++++ VY+VMEL GGEL DR++ Q F+ER+A +L + + YLH+ + H
Sbjct: 479 TLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVH 538
Query: 182 RNLKPENLLYY-HPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 240
R+LKP N+LY G I + DFG A ++G+ + T C T ++APEVL R+ Y
Sbjct: 539 RDLKPSNILYRDESGSPESIRVCDFGFA-KQLRAGNGLLMTPCYTANFVAPEVLKRQGYD 597
Query: 241 SAVDMWALGVITYALLSGFLPF---DDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFI 297
+A D+W+LG++ Y +L+GF PF D++ + +I GKY +G W SIS AKD +
Sbjct: 598 AACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVV 657
Query: 298 DKLLILEAGHRMSAGQALDHPWVI 321
K+L ++ R++A Q L HPWV+
Sbjct: 658 SKMLHVDPHQRLTAMQVLKHPWVV 681
Score = 135 bits (340), Expect = 6e-32
Identities = 91/280 (32%), Positives = 154/280 (55%), Gaps = 21/280 (7%)
Query: 54 KFDPRVLARYDIKALIGTGSFSRVV---RVEQKTTKKPFAIKVMETREREGREACVSELS 110
K DP +++++ ++G GS+ +V +V+ + +A+KV++ + R+ S++
Sbjct: 61 KADP---SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKME 117
Query: 111 --VLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVA 168
+L V+H +IV+L F+TE ++Y++++ GG+LF RL + FTE D L +A
Sbjct: 118 RDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELA 177
Query: 169 DGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEY 228
+ +LH+L I +R+LKPEN+L EE I ITDFGL+ D + CGT EY
Sbjct: 178 LALDHLHSLGIIYRDLKPENILL---DEEGHIKITDFGLSKEA-IDHDKRAYSFCGTIEY 233
Query: 229 IAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPS 288
+APEV+ R+ +T + D W+ GV+ + +L+G LPF + + ILK K G P
Sbjct: 234 MAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAK---LGMP-QF 289
Query: 289 ISHLAKDFIDKLLILEAGHRMSAG-----QALDHPWVITM 323
+S A+ + L +R+ AG + HP+ +T+
Sbjct: 290 LSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTI 329
>gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2
isoform a [Homo sapiens]
Length = 733
Score = 186 bits (471), Expect = 4e-47
Identities = 101/264 (38%), Positives = 156/264 (59%), Gaps = 10/264 (3%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVS-HRYIV 121
Y+IK IG GS+S R K T +A+K+++ +R+ E E+ +L R H I+
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE----EIEILLRYGQHPNII 470
Query: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181
L ++++ VY+VMEL GGEL DR++ Q F+ER+A +L + + YLH+ + H
Sbjct: 471 TLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVH 530
Query: 182 RNLKPENLLYY-HPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 240
R+LKP N+LY G I + DFG A ++G+ + T C T ++APEVL R+ Y
Sbjct: 531 RDLKPSNILYRDESGSPESIRVCDFGFA-KQLRAGNGLLMTPCYTANFVAPEVLKRQGYD 589
Query: 241 SAVDMWALGVITYALLSGFLPF---DDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFI 297
+A D+W+LG++ Y +L+GF PF D++ + +I GKY +G W SIS AKD +
Sbjct: 590 AACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVV 649
Query: 298 DKLLILEAGHRMSAGQALDHPWVI 321
K+L ++ R++A Q L HPWV+
Sbjct: 650 SKMLHVDPHQRLTAMQVLKHPWVV 673
Score = 135 bits (340), Expect = 6e-32
Identities = 91/280 (32%), Positives = 154/280 (55%), Gaps = 21/280 (7%)
Query: 54 KFDPRVLARYDIKALIGTGSFSRVV---RVEQKTTKKPFAIKVMETREREGREACVSELS 110
K DP +++++ ++G GS+ +V +V+ + +A+KV++ + R+ S++
Sbjct: 53 KADP---SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKME 109
Query: 111 --VLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVA 168
+L V+H +IV+L F+TE ++Y++++ GG+LF RL + FTE D L +A
Sbjct: 110 RDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELA 169
Query: 169 DGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEY 228
+ +LH+L I +R+LKPEN+L EE I ITDFGL+ D + CGT EY
Sbjct: 170 LALDHLHSLGIIYRDLKPENILL---DEEGHIKITDFGLSKEA-IDHDKRAYSFCGTIEY 225
Query: 229 IAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPS 288
+APEV+ R+ +T + D W+ GV+ + +L+G LPF + + ILK K G P
Sbjct: 226 MAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAK---LGMP-QF 281
Query: 289 ISHLAKDFIDKLLILEAGHRMSAG-----QALDHPWVITM 323
+S A+ + L +R+ AG + HP+ +T+
Sbjct: 282 LSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTI 321
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 183 bits (464), Expect = 3e-46
Identities = 98/277 (35%), Positives = 159/277 (57%), Gaps = 5/277 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRVSHRYI 120
Y + +G G+FS V R +KT+ + +A K++ T++ R+ E + R + H I
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 121 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 180
V+L + E Y+V +L TGGELF+ ++A+ ++E DA + + + + ++H I
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 181 HRNLKPENLLYYHPGEESKILITDFGLAYSGK-KSGDWTMKTLCGTPEYIAPEVLLRKPY 239
HR+LKPENLL + + + + DFGLA + + W GTP Y++PEVL + PY
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWF--GFAGTPGYLSPEVLRKDPY 191
Query: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
VD+WA GVI Y LL G+ PF DE Q +LY++I G Y++ W +++ AK+ I++
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 300 LLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
+L + R++A QAL HPWV + +SM + Q +
Sbjct: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 183 bits (464), Expect = 3e-46
Identities = 98/277 (35%), Positives = 159/277 (57%), Gaps = 5/277 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRVSHRYI 120
Y + +G G+FS V R +KT+ + +A K++ T++ R+ E + R + H I
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 121 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 180
V+L + E Y+V +L TGGELF+ ++A+ ++E DA + + + + ++H I
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 181 HRNLKPENLLYYHPGEESKILITDFGLAYSGK-KSGDWTMKTLCGTPEYIAPEVLLRKPY 239
HR+LKPENLL + + + + DFGLA + + W GTP Y++PEVL + PY
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWF--GFAGTPGYLSPEVLRKDPY 191
Query: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
VD+WA GVI Y LL G+ PF DE Q +LY++I G Y++ W +++ AK+ I++
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 300 LLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
+L + R++A QAL HPWV + +SM + Q +
Sbjct: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 183 bits (464), Expect = 3e-46
Identities = 98/277 (35%), Positives = 159/277 (57%), Gaps = 5/277 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRVSHRYI 120
Y + +G G+FS V R +KT+ + +A K++ T++ R+ E + R + H I
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 121 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 180
V+L + E Y+V +L TGGELF+ ++A+ ++E DA + + + + ++H I
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 181 HRNLKPENLLYYHPGEESKILITDFGLAYSGK-KSGDWTMKTLCGTPEYIAPEVLLRKPY 239
HR+LKPENLL + + + + DFGLA + + W GTP Y++PEVL + PY
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWF--GFAGTPGYLSPEVLRKDPY 191
Query: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
VD+WA GVI Y LL G+ PF DE Q +LY++I G Y++ W +++ AK+ I++
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 300 LLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
+L + R++A QAL HPWV + +SM + Q +
Sbjct: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 183 bits (464), Expect = 3e-46
Identities = 98/277 (35%), Positives = 159/277 (57%), Gaps = 5/277 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRVSHRYI 120
Y + +G G+FS V R +KT+ + +A K++ T++ R+ E + R + H I
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 121 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 180
V+L + E Y+V +L TGGELF+ ++A+ ++E DA + + + + ++H I
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 181 HRNLKPENLLYYHPGEESKILITDFGLAYSGK-KSGDWTMKTLCGTPEYIAPEVLLRKPY 239
HR+LKPENLL + + + + DFGLA + + W GTP Y++PEVL + PY
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWF--GFAGTPGYLSPEVLRKDPY 191
Query: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
VD+WA GVI Y LL G+ PF DE Q +LY++I G Y++ W +++ AK+ I++
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 300 LLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
+L + R++A QAL HPWV + +SM + Q +
Sbjct: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 183 bits (464), Expect = 3e-46
Identities = 98/277 (35%), Positives = 159/277 (57%), Gaps = 5/277 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGRE--ACVSELSVLRRVSHRYI 120
Y + +G G+FS V R +KT+ + +A K++ T++ R+ E + R + H I
Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Query: 121 VQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQIT 180
V+L + E Y+V +L TGGELF+ ++A+ ++E DA + + + + ++H I
Sbjct: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
Query: 181 HRNLKPENLLYYHPGEESKILITDFGLAYSGK-KSGDWTMKTLCGTPEYIAPEVLLRKPY 239
HR+LKPENLL + + + + DFGLA + + W GTP Y++PEVL + PY
Sbjct: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWF--GFAGTPGYLSPEVLRKDPY 191
Query: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
VD+WA GVI Y LL G+ PF DE Q +LY++I G Y++ W +++ AK+ I++
Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
Query: 300 LLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAI 336
+L + R++A QAL HPWV + +SM + Q +
Sbjct: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 182 bits (463), Expect = 3e-46
Identities = 95/282 (33%), Positives = 163/282 (57%), Gaps = 4/282 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQ 122
YDI+ +G+G F +V R+ +K T+K +A K + + +E E+S++ + H +VQ
Sbjct: 1464 YDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQ 1523
Query: 123 LMEIFETEDQVYMVMELATGGELFDRLIAQG-SFTERDAVRILQMVADGIRYLHALQITH 181
++ FE + + MV+E+ +GGELF+R+I + TER+ ++ ++ +++G+ Y+H I H
Sbjct: 1524 CVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVH 1583
Query: 182 RNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTS 241
+LKPEN++ + ++I + DFGLA + +G ++K L GTPE++APEV+ +P
Sbjct: 1584 LDLKPENIMCVNK-TGTRIKLIDFGLARRLENAG--SLKVLFGTPEFVAPEVINYEPIGY 1640
Query: 242 AVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLL 301
A DMW++GVI Y L+SG PF ++ + +++ E + IS AKDFI LL
Sbjct: 1641 ATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLL 1700
Query: 302 ILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQR 343
+ +R+ Q L HPW++ K L + + M R
Sbjct: 1701 KKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMAR 1742
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 182 bits (463), Expect = 3e-46
Identities = 95/282 (33%), Positives = 163/282 (57%), Gaps = 4/282 (1%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQ 122
YDI+ +G+G F +V R+ +K T+K +A K + + +E E+S++ + H +VQ
Sbjct: 1395 YDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQ 1454
Query: 123 LMEIFETEDQVYMVMELATGGELFDRLIAQG-SFTERDAVRILQMVADGIRYLHALQITH 181
++ FE + + MV+E+ +GGELF+R+I + TER+ ++ ++ +++G+ Y+H I H
Sbjct: 1455 CVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVH 1514
Query: 182 RNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTS 241
+LKPEN++ + ++I + DFGLA + +G ++K L GTPE++APEV+ +P
Sbjct: 1515 LDLKPENIMCVNK-TGTRIKLIDFGLARRLENAG--SLKVLFGTPEFVAPEVINYEPIGY 1571
Query: 242 AVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLL 301
A DMW++GVI Y L+SG PF ++ + +++ E + IS AKDFI LL
Sbjct: 1572 ATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLL 1631
Query: 302 ILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQR 343
+ +R+ Q L HPW++ K L + + M R
Sbjct: 1632 KKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMAR 1673
>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
Length = 454
Score = 182 bits (463), Expect = 3e-46
Identities = 99/265 (37%), Positives = 159/265 (60%), Gaps = 9/265 (3%)
Query: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETRE----REG--REACVSELSVLRRVS 116
Y++ +G+G F+ V + QK T K +A K ++ R R G RE E+++LR +
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72
Query: 117 HRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHA 176
H I+ L +IFE + V +++EL +GGELFD L + S TE +A + L+ + DG+ YLH+
Sbjct: 73 HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132
Query: 177 LQITHRNLKPENLLYYHPGEES-KILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLL 235
+I H +LKPEN++ + +I + DFG+A+ + ++ K + GTPE++APE++
Sbjct: 133 KRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEF--KNIFGTPEFVAPEIVN 190
Query: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
+P DMW++GVITY LLSG PF E++ I Y++ E + + S LAKD
Sbjct: 191 YEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKD 250
Query: 296 FIDKLLILEAGHRMSAGQALDHPWV 320
FI +LL+ + RM+ Q+L+H W+
Sbjct: 251 FIRRLLVKDPKRRMTIAQSLEHSWI 275
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,718,605
Number of Sequences: 37866
Number of extensions: 633329
Number of successful extensions: 4571
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 592
Number of HSP's successfully gapped in prelim test: 192
Number of HSP's that attempted gapping in prelim test: 2372
Number of HSP's gapped (non-prelim): 944
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.