Guide to the Human Genome
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Search of human proteins with 148727311

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
         (1318 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148727311 hypothetical protein LOC389690 [Homo sapiens]           2647   0.0  
gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5...   312   2e-84
gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]       312   2e-84
gi|223278410 hypothetical protein LOC374977 [Homo sapiens]            290   8e-78
gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapi...   223   9e-58
gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     206   9e-53
gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     206   1e-52
gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     202   2e-51
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]             196   1e-49
gi|154937380 hypothetical protein LOC642475 [Homo sapiens]            159   1e-38
gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]   111   4e-24
gi|117956387 hypothetical protein LOC80133 [Homo sapiens]              89   2e-17
gi|187761375 maestro isoform a [Homo sapiens]                          74   7e-13
gi|187761381 maestro isoform d [Homo sapiens]                          73   2e-12
gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]    71   8e-12
gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens]        49   4e-05
gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens]        49   4e-05
gi|187761377 maestro isoform b [Homo sapiens]                          33   1.8  
gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo ...    33   2.4  
gi|5032187 transducer of ERBB2, 1 [Homo sapiens]                       32   4.0  
gi|187761379 maestro isoform c [Homo sapiens]                          32   5.3  
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]       31   6.9  
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]        31   6.9  
gi|187828635 NOL1/NOP2/Sun domain family, member 7 [Homo sapiens]      31   6.9  
gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sap...    31   9.0  
gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sap...    31   9.0  
gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sap...    31   9.0  

>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score = 2647 bits (6862), Expect = 0.0
 Identities = 1318/1318 (100%), Positives = 1318/1318 (100%)

Query: 1    MDRQCSERPYSCTPTGRVSSAVSQNSRISPPVSTSMKDSSCMKVHQDSARRDRWSHPTTI 60
            MDRQCSERPYSCTPTGRVSSAVSQNSRISPPVSTSMKDSSCMKVHQDSARRDRWSHPTTI
Sbjct: 1    MDRQCSERPYSCTPTGRVSSAVSQNSRISPPVSTSMKDSSCMKVHQDSARRDRWSHPTTI 60

Query: 61   LLHKSQSSQATLMLQEHRMFMGEAYSAATGFKMLQDMNSADPFHLKYIIKKIKNMAHGSP 120
            LLHKSQSSQATLMLQEHRMFMGEAYSAATGFKMLQDMNSADPFHLKYIIKKIKNMAHGSP
Sbjct: 61   LLHKSQSSQATLMLQEHRMFMGEAYSAATGFKMLQDMNSADPFHLKYIIKKIKNMAHGSP 120

Query: 121  KLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLALENMTKATE 180
            KLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLALENMTKATE
Sbjct: 121  KLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLALENMTKATE 180

Query: 181  LEDIYQDAASNMLVAICRHSWRVVAQHLETELLTGVFPHRSLLYVMGVLSSSEELFSQED 240
            LEDIYQDAASNMLVAICRHSWRVVAQHLETELLTGVFPHRSLLYVMGVLSSSEELFSQED
Sbjct: 181  LEDIYQDAASNMLVAICRHSWRVVAQHLETELLTGVFPHRSLLYVMGVLSSSEELFSQED 240

Query: 241  KACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAE 300
            KACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAE
Sbjct: 241  KACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAE 300

Query: 301  KNGATVRRHLQALLETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLP 360
            KNGATVRRHLQALLETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLP
Sbjct: 301  KNGATVRRHLQALLETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLP 360

Query: 361  SSSPKNSEDLRWKWASSTILLAYGQVAAKARAHILPWVDNIVSRMVFYFHYSSWDETLKQ 420
            SSSPKNSEDLRWKWASSTILLAYGQVAAKARAHILPWVDNIVSRMVFYFHYSSWDETLKQ
Sbjct: 361  SSSPKNSEDLRWKWASSTILLAYGQVAAKARAHILPWVDNIVSRMVFYFHYSSWDETLKQ 420

Query: 421  SFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAMHIASS 480
            SFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAMHIASS
Sbjct: 421  SFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAMHIASS 480

Query: 481  LCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARERAGWTH 540
            LCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARERAGWTH
Sbjct: 481  LCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARERAGWTH 540

Query: 541  QGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLASEKAH 600
            QGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLASEKAH
Sbjct: 541  QGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLASEKAH 600

Query: 601  ERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLEGASHL 660
            ERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLEGASHL
Sbjct: 601  ERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLEGASHL 660

Query: 661  YQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIFQLCSF 720
            YQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIFQLCSF
Sbjct: 661  YQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIFQLCSF 720

Query: 721  QVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEIVSSMAQ 780
            QVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEIVSSMAQ
Sbjct: 721  QVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEIVSSMAQ 780

Query: 781  AIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQP 840
            AIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQP
Sbjct: 781  AIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQP 840

Query: 841  TSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEG 900
            TSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEG
Sbjct: 841  TSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEG 900

Query: 901  YPKLFLALLTQMHYVLELNLPSEPQPKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHWHD 960
            YPKLFLALLTQMHYVLELNLPSEPQPKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHWHD
Sbjct: 901  YPKLFLALLTQMHYVLELNLPSEPQPKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHWHD 960

Query: 961  FAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVA 1020
            FAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVA
Sbjct: 961  FAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVA 1020

Query: 1021 ILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQG 1080
            ILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQG
Sbjct: 1021 ILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQG 1080

Query: 1081 QLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFNDERDGIRA 1140
            QLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFNDERDGIRA
Sbjct: 1081 QLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFNDERDGIRA 1140

Query: 1141 AAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRW 1200
            AAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRW
Sbjct: 1141 AAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRW 1200

Query: 1201 RLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFI 1260
            RLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFI
Sbjct: 1201 RLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFI 1260

Query: 1261 GHTICYHPQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVSARPKQ 1318
            GHTICYHPQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVSARPKQ
Sbjct: 1261 GHTICYHPQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVSARPKQ 1318


>gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5
            [Homo sapiens]
          Length = 1218

 Score =  312 bits (799), Expect = 2e-84
 Identities = 315/1160 (27%), Positives = 504/1160 (43%), Gaps = 111/1160 (9%)

Query: 188  AASNMLVAICRHSWRVVAQHLETELLTGVFPHRSLLYVMGVLSS-SEELFSQEDKACWEE 246
            AA  +L  +  +   ++ QH ET          ++  ++G L   +EE   QE+   WEE
Sbjct: 136  AALRLLSVLHPNIHPLLGQHWET----------TVPLLLGYLDEHTEETLPQEE---WEE 182

Query: 247  QLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAEKNGATV 306
            +L+     ++  +S + W  +L   L        E   EK FL+   G  L A  +   V
Sbjct: 183  KLLMFLRDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVV 242

Query: 307  RRHLQALLETS-HQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLPSSSP- 364
            R+HLQ LLET+ +Q   +REG+A   G+ A  HL+D  A L+ F RS   R S+   +  
Sbjct: 243  RKHLQELLETARYQEEAEREGLACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIF 302

Query: 365  KNSEDLRWKWASSTILLAYGQVAAKA-RAHILPWVDNIVSRMVFYFHYSSW--------- 414
            K+  +   +   S ++L YG VAA+A R  +L  V++ + R +   H+S+          
Sbjct: 303  KDRSENEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQ-HFSTKVLGIKVETK 361

Query: 415  DETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQA 474
            D  LK   + +  M+  A+  S  A S+ F + +EL+  +M  +  EP D+L T  R++A
Sbjct: 362  DPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKA 421

Query: 475  MHIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARE 534
            M   + L  + P +D + ++ ++  C  S+ AL                      P  +E
Sbjct: 422  MLTCTYLVSVEPALDEQARADVIHGCLHSIMAL---------------------LPEPKE 460

Query: 535  RAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWL 594
              G   +               SLY  T+ AL+ +L SL+ +N T   L  ++ HL  W+
Sbjct: 461  EDGGCQK---------------SLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWI 505

Query: 595  ASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSL 654
             S + HER RA+    +LL++   +  +     F  +G L+G+    C D   AT++ ++
Sbjct: 506  KSPRGHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIGLFSPRCADLWPATRQEAV 565

Query: 655  EGASHLYQLLMCHKTGEALQAESQAPKELSQ----AHSDGAPLWNSRDQKATPLGPQEMA 710
            +    L  L + ++       +  A + LS      H D A L                 
Sbjct: 566  DCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAIL----------------- 608

Query: 711  KNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGA 770
                F  C   V + I ++L   +L  L+ T  + LG       +AA+ M+   +QE G 
Sbjct: 609  ----FHTCH-SVGQIIAKRLPPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGG 663

Query: 771  KL-EIVSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTF 829
             L E V  +   +R +L             H++ LLA  H   +V++ L   +PLDSHT 
Sbjct: 664  VLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTC 723

Query: 830  QLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDS---SPCPKEKTYLRLLAAMNMLHE 886
             LWRAL      +  VL  LL  +  R +P   S +      P     L  L+A   L E
Sbjct: 724  MLWRALAVEPRLAAQVLGLLLEKMS-RDVPFKESRAFLLGRTPDRVATLLPLSATCALFE 782

Query: 887  LQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQPKQQ---AQEAAVPSPQSCST 943
            +        AV E YP+LF+ LL ++   + + LP   Q +++   +   A  + + CS+
Sbjct: 783  VMSTPAAGPAVLELYPQLFVVLLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEPCSS 842

Query: 944  SLEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLR 1003
            +++ L+S+L  +G       ++L+G WEL  T   + +G   LARAM ++   ++P VL+
Sbjct: 843  AVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLVLK 902

Query: 1004 QLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQ 1063
             L  +  S  E +R      L + L S V  +++   + L  LA    D    VR L L+
Sbjct: 903  TLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLAARQKDTCASVRRLVLR 962

Query: 1064 GLSNILFH-PDK-----GSLLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTG 1117
            GL+N+    PDK       LL   +  L DG    S   +  ++G ++  +H + +    
Sbjct: 963  GLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEAMLG-LARLVHLVESWDLR 1021

Query: 1118 SQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLK 1177
            S  L VAI  R FF+ E+   R A++ LFG L              QV   + PLLLHL+
Sbjct: 1022 SGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQ 1081

Query: 1178 DQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAWE-RGLSARHFL-WTC--LMTRSQEE 1233
            D    VA+  +F    C   L    L   F     E R L    FL  TC  LM    + 
Sbjct: 1082 DPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDL 1141

Query: 1234 FSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAVDTNLLFRTFEHLRSD 1293
                L+  L Y  S   +++    LF G  + +      +    VD + L    + L  D
Sbjct: 1142 LGRLLTTCLFYFKSSWENVRAAAPLFTGFLVLHSEP---RQQPQVDLDQLIAALQILLKD 1198

Query: 1294 PEPSIREFATSQLSFLQKVS 1313
            P P +R  A   L  L K++
Sbjct: 1199 PAPEVRTRAAEALGRLVKLA 1218


>gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]
          Length = 1641

 Score =  312 bits (799), Expect = 2e-84
 Identities = 315/1160 (27%), Positives = 504/1160 (43%), Gaps = 111/1160 (9%)

Query: 188  AASNMLVAICRHSWRVVAQHLETELLTGVFPHRSLLYVMGVLSS-SEELFSQEDKACWEE 246
            AA  +L  +  +   ++ QH ET          ++  ++G L   +EE   QE+   WEE
Sbjct: 559  AALRLLSVLHPNIHPLLGQHWET----------TVPLLLGYLDEHTEETLPQEE---WEE 605

Query: 247  QLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAEKNGATV 306
            +L+     ++  +S + W  +L   L        E   EK FL+   G  L A  +   V
Sbjct: 606  KLLMFLRDTLAIISDNAWICQLSLELCRQLPCYDEAPQEKNFLYKCIGTTLGAASSKEVV 665

Query: 307  RRHLQALLETS-HQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLPSSSP- 364
            R+HLQ LLET+ +Q   +REG+A   G+ A  HL+D  A L+ F RS   R S+   +  
Sbjct: 666  RKHLQELLETARYQEEAEREGLACCFGICAISHLEDTLAQLEDFVRSEVFRKSIGILNIF 725

Query: 365  KNSEDLRWKWASSTILLAYGQVAAKA-RAHILPWVDNIVSRMVFYFHYSSW--------- 414
            K+  +   +   S ++L YG VAA+A R  +L  V++ + R +   H+S+          
Sbjct: 726  KDRSENEVEKVKSALILCYGHVAARAPRELVLAKVESDILRNICQ-HFSTKVLGIKVETK 784

Query: 415  DETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQA 474
            D  LK   + +  M+  A+  S  A S+ F + +EL+  +M  +  EP D+L T  R++A
Sbjct: 785  DPALKLCLVQSVCMVSRAICSSTQAGSFHFTRKAELVAQMMEFIRAEPPDSLRTPIRKKA 844

Query: 475  MHIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARE 534
            M   + L  + P +D + ++ ++  C  S+ AL                      P  +E
Sbjct: 845  MLTCTYLVSVEPALDEQARADVIHGCLHSIMAL---------------------LPEPKE 883

Query: 535  RAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWL 594
              G   +               SLY  T+ AL+ +L SL+ +N T   L  ++ HL  W+
Sbjct: 884  EDGGCQK---------------SLYLETLHALEDLLTSLLQRNMTPQGLQIMIEHLSPWI 928

Query: 595  ASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSL 654
             S + HER RA+    +LL++   +  +     F  +G L+G+    C D   AT++ ++
Sbjct: 929  KSPRGHERARALGLSALLLRYFLEHLRVSALVPFHNLGLLIGLFSPRCADLWPATRQEAV 988

Query: 655  EGASHLYQLLMCHKTGEALQAESQAPKELSQ----AHSDGAPLWNSRDQKATPLGPQEMA 710
            +    L  L + ++       +  A + LS      H D A L                 
Sbjct: 989  DCVYSLLYLQLGYEGFSRDYRDDVAERLLSLKDGLVHPDPAIL----------------- 1031

Query: 711  KNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGA 770
                F  C   V + I ++L   +L  L+ T  + LG       +AA+ M+   +QE G 
Sbjct: 1032 ----FHTCH-SVGQIIAKRLPPDQLISLLLTMFEALGDPEKNCSRAATVMINCLLQERGG 1086

Query: 771  KL-EIVSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTF 829
             L E V  +   +R +L             H++ LLA  H   +V++ L   +PLDSHT 
Sbjct: 1087 VLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAAVVSSLLGSPLPLDSHTC 1146

Query: 830  QLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDS---SPCPKEKTYLRLLAAMNMLHE 886
             LWRAL      +  VL  LL  +  R +P   S +      P     L  L+A   L E
Sbjct: 1147 MLWRALAVEPRLAAQVLGLLLEKMS-RDVPFKESRAFLLGRTPDRVATLLPLSATCALFE 1205

Query: 887  LQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQPKQQ---AQEAAVPSPQSCST 943
            +        AV E YP+LF+ LL ++   + + LP   Q +++   +   A  + + CS+
Sbjct: 1206 VMSTPAAGPAVLELYPQLFVVLLLRVSCTVGVQLPRNLQAQERRGASPALATRNLEPCSS 1265

Query: 944  SLEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLR 1003
            +++ L+S+L  +G       ++L+G WEL  T   + +G   LARAM ++   ++P VL+
Sbjct: 1266 AVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEEGATRLARAMAEHAGPRLPLVLK 1325

Query: 1004 QLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQ 1063
             L  +  S  E +R      L + L S V  +++   + L  LA    D    VR L L+
Sbjct: 1326 TLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDSLLESLAARQKDTCASVRRLVLR 1385

Query: 1064 GLSNILFH-PDK-----GSLLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTG 1117
            GL+N+    PDK       LL   +  L DG    S   +  ++G ++  +H + +    
Sbjct: 1386 GLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEAMLG-LARLVHLVESWDLR 1444

Query: 1118 SQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLK 1177
            S  L VAI  R FF+ E+   R A++ LFG L              QV   + PLLLHL+
Sbjct: 1445 SGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQ 1504

Query: 1178 DQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAWE-RGLSARHFL-WTC--LMTRSQEE 1233
            D    VA+  +F    C   L    L   F     E R L    FL  TC  LM    + 
Sbjct: 1505 DPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFGEFLNTTCKHLMHHFPDL 1564

Query: 1234 FSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAVDTNLLFRTFEHLRSD 1293
                L+  L Y  S   +++    LF G  + +      +    VD + L    + L  D
Sbjct: 1565 LGRLLTTCLFYFKSSWENVRAAAPLFTGFLVLHSEP---RQQPQVDLDQLIAALQILLKD 1621

Query: 1294 PEPSIREFATSQLSFLQKVS 1313
            P P +R  A   L  L K++
Sbjct: 1622 PAPEVRTRAAEALGRLVKLA 1641



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 1/139 (0%)

Query: 93  MLQDMNSADPFHLKYIIKKIKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMV 152
           +L  +   DP   + +   + ++    P   +    +Y   + +++  ++  + + +E V
Sbjct: 13  LLDAITDKDPLVQEQVCSALCSLGEVRPVETLRACEEYLRQHDKLAHPYRAAVLRAMERV 72

Query: 153 IGA-SDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQHLETE 211
           + + +  L++    T   LA   MTK  +L   +Q AAS +LVA+ R     V + L   
Sbjct: 73  LSSRASELDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRR 132

Query: 212 LLTGVFPHRSLLYVMGVLS 230
           L  G  PH ++L+ +  LS
Sbjct: 133 LHPGTLPHCAVLHTLASLS 151


>gi|223278410 hypothetical protein LOC374977 [Homo sapiens]
          Length = 1323

 Score =  290 bits (741), Expect = 8e-78
 Identities = 240/875 (27%), Positives = 418/875 (47%), Gaps = 94/875 (10%)

Query: 450  LLQCLMVLMEKEPQDTLCTRSRQQAMHIASSLCKLRPPIDLERKSQLLSTCFRSVFALPL 509
            +++ +M  +++EP D+L +  R+QAM I + L   +P + +  +S+L++ C  SVF+LP 
Sbjct: 458  MIKKIMRQIQEEPLDSLSSSVRKQAMEILTQLSHTQPTLGMRERSELVNVCVHSVFSLPS 517

Query: 510  LDALEKHTCLFLEPPNIQLWPVARERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFM 569
            + A+++                 ++ A               +E +Q+LY +T+EAL  +
Sbjct: 518  VQAMQE-----------------KDEAK--------------AETIQALYHQTLEALQTL 546

Query: 570  LQSLIMQNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFK 629
            L++L +++PT   L  +L  L  W+ S KAHER RAV++ + +L  +           F 
Sbjct: 547  LKALFIEDPTPAGLKSILEALGPWMNSGKAHERARAVNTNVSVLNHMLLTLPFFMPLGFP 606

Query: 630  RIGQLVGILGMLCQDPDRATQRCSLEGASHLYQLLMCHKTGEALQAESQAPKELSQAHSD 689
             +G L+G L +   DPD      +L+G   LY +L   K   A   E    KEL      
Sbjct: 607  ALGLLLGRLILHIGDPDEEIGCEALDGIIILYTILELQK--RARDKEETNKKEL------ 658

Query: 690  GAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGL--- 746
                + S      P  P    +N +      +VI++    L   ++ DL+  A++GL   
Sbjct: 659  ----YESNKHFLGPYNPVSPCQNIL------RVIEEFGDFLGPQQIKDLLLAALEGLKGS 708

Query: 747  ----GSTSPFRVQAASEMLLTAVQE---HGAKLEIVSSMAQAIRLRLCSVHIPQAKEKTL 799
                G  S   +Q ASE++L++V E   H A LE++  + Q I ++L  +  P+A++  L
Sbjct: 709  SEAPGKDSREMMQLASEVMLSSVLEWYRHRA-LEVIPEIMQGIYMQLSHIQEPRARQVAL 767

Query: 800  HAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQPTSHL--VLTTLLACLQERP 857
              ++LLA S   E+V   L   +PL+S+  ++WR L   +P+  +  +L  LL  L+E+P
Sbjct: 768  LPVSLLASSFMTEVVVALLMCPLPLNSNGAEMWRQLILCKPSCDVRDLLDLLLGSLKEKP 827

Query: 858  LPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEGYPKLFLALLTQMHYVLE 917
            + T    +S  P        LAA + L EL         V+  YP+L LALL Q+HY + 
Sbjct: 828  V-TKEGRASIVP--------LAAASGLCELLSVNSCMGRVRRIYPQLLLALLIQVHYHIG 878

Query: 918  LNLPSEPQPKQQAQEAAVPSP-QSCSTSLEALKSLLSTTGHWHDFAHLELQGSWELFTTI 976
            LNLP    P +  ++ A PSP       ++ +K+LL   G  ++   LE QG WEL   +
Sbjct: 879  LNLPGCVAPPKDTKKGAQPSPFVPVRWVVKVVKTLLLRMGCSYETTFLEDQGGWELMEQV 938

Query: 977  HTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEV 1036
             ++ +GV LLARAMVQ  C+++  +L  L+P L+   E+ R  A     + L    +  +
Sbjct: 939  ESHHRGVALLARAMVQYSCQELCRILYLLIPLLERGDEKHRITATAFFVELLQMEQVRRI 998

Query: 1037 LPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQGQLRPLLDGFFQSSDQV 1096
             P++ +L  +A+GL    P ++VLS++GL  +    +K + ++  L  ++ G       +
Sbjct: 999  -PEEYSLGRMAEGLSHHDPIMKVLSIRGLVILARRSEKTAKVKALLPSMVKGLKNMDGML 1057

Query: 1097 IVCIMGTVSDTLHRLGA--QGTGSQSLGVAISTRSF------FNDERDGIRAAAMALFGD 1148
            +V       + +H L A  +G   + +  A+           F+D R+ +R++ + L+G 
Sbjct: 1058 VV-------EAVHNLKAVFKGRDQKLMDSAVYVEMLQILLPHFSDAREVVRSSCINLYGK 1110

Query: 1149 LVAAMADRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRWRLLHTLFC 1208
            +V  +       +  Q+  ++VPLLL +++    V+ +   T  RC+  + W L    + 
Sbjct: 1111 VVQKLRAPRTQAMEEQLVSTLVPLLLTMQEGNSKVSQKCVKTLLRCSYFMAWELPKRAYS 1170

Query: 1209 TLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFIGHTI-CYH 1267
               W+        +  CL+   ++   I LSQ+L Y  +    ++    +FIG  + C  
Sbjct: 1171 RKPWDNQQQTVAKICKCLVNTHRDSAFIFLSQSLEYAKNSRASLRKCSVMFIGSLVPCME 1230

Query: 1268 PQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFA 1302
                   LN V   L     ++LR DPE S+  +A
Sbjct: 1231 SIMTEDRLNEVKAAL-----DNLRHDPEASVCIYA 1260


>gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapiens]
          Length = 1052

 Score =  223 bits (568), Expect = 9e-58
 Identities = 220/939 (23%), Positives = 404/939 (43%), Gaps = 91/939 (9%)

Query: 398  VDNIVSRMVFYFHYSSWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVL 457
            V+ ++  +   F+     E  K  FL     L  A+   E A S+     ++++  L VL
Sbjct: 169  VEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVL 228

Query: 458  MEKEPQDTLCTRSRQQAMHIASSLC--KLRPPIDLERKSQLLSTCFRSVFALPLLDALEK 515
            +++E   +L +  RQ+     + L    +   +  E +++L S   +S+  LP +  L +
Sbjct: 229  VQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQ 288

Query: 516  HTCLFLEPPNIQLWPVARERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIM 575
               +    PN                            + + LY +T +A   MLQSL++
Sbjct: 289  IQEIM---PNGTC-------------------------NTECLYRQTFQAFSEMLQSLVV 320

Query: 576  QNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLV 635
            ++P  + L  ++ HL  WL S K HER+RA  S   +LK L+ +  L     F+R+G LV
Sbjct: 321  KDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLV 380

Query: 636  GILGMLCQDPDRATQRCSLEGASHLYQLLM-------CHKTGEALQAESQAPKELSQAHS 688
             ++ +LC DP       + EG   L  + +         K  + L+      +E  + HS
Sbjct: 381  ALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHS 440

Query: 689  DGAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGS 748
              A                       F  C F++ +     L   EL   I T  D L +
Sbjct: 441  SAA---------------------KCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKT 479

Query: 749  TS-PFRVQAASEMLLTAVQEHGAKLEIVSSMAQAIRLRLCSVHIPQAKEKTLHAITL-LA 806
               P   ++A E+LLT  +   ++ E V  +   I  +L  +  P+ +++ ++ ++L ++
Sbjct: 480  LKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFIS 539

Query: 807  RSHTCELVATFLNI-SIPLDSHTFQLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDS 865
            R    ++V +FL    +P + H  ++WR L    P++  +L  LL  LQ+         +
Sbjct: 540  RPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQK-------CHN 592

Query: 866  SPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQ 925
             P  ++  Y+  +AA + L+E+      + A    +P+L + LL Q+H+ + L +     
Sbjct: 593  EPAQEKMAYV-AVAATDALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVDI 651

Query: 926  PKQQAQEAAVPSPQS-CSTSLEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVG 984
            P     E  VPS  +    +++A K+LL  T    +F  +E    W L      + +G+ 
Sbjct: 652  PSGLYTEQEVPSEVTPLCFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGKDGHLQGLF 711

Query: 985  LLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALT 1044
            LLA A+++ +      V+  L+P L    ++ +  +     + L SPV  + LP   ++ 
Sbjct: 712  LLANALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRSPV-AKRLPSIYSVA 770

Query: 1045 VLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQGQLRPLLDGFFQSSDQVIVCIMGTV 1104
                 L D +   R+L L+GL N++ H +    ++  L  ++D   ++ +++++  +  +
Sbjct: 771  RFKDWLQDGNHLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQIL 830

Query: 1105 SDTLHRLGAQGTGSQSLGVAISTR-SFFNDERDGIRAAAMALFGDLVAAMADRELSGLRT 1163
               +  +        +L   + T  S F D R  +   ++ LFG  + ++ + +   +  
Sbjct: 831  LQLVRTM-----DFTTLAAMMRTLFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIEN 885

Query: 1164 QVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAW-----ERGLSA 1218
            QV  S+VPLLL+ +D+  AVA +++     CA  L+W+L   ++    W     E G   
Sbjct: 886  QVLDSLVPLLLYSQDENDAVAEESRQVLTICAQFLKWKLPQEVYSKDPWHIKPTEAGTIC 945

Query: 1219 RHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAV 1278
            R F   C     + + +I L Q L Y  +    I+    LF+G    Y        L  +
Sbjct: 946  RFFEKKC-----KGKINI-LEQTLMYSKNPKLPIRRSAVLFVGLLSKYMDH---NELRRM 996

Query: 1279 DTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVSARPK 1317
             T+ +      L  DPEPS+   A+  L  +Q   A PK
Sbjct: 997  GTDWIEDDLRDLLCDPEPSLCIIASQTLLLVQMARAEPK 1035


>gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1706

 Score =  206 bits (525), Expect = 9e-53
 Identities = 252/1101 (22%), Positives = 442/1101 (40%), Gaps = 101/1101 (9%)

Query: 240  DKACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQA 299
            D+  WE++LIQ    S+       WS  L   L     +    S EK FL+   G  L  
Sbjct: 668  DQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLAT 727

Query: 300  EKNGATVRRHLQALL-ETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFG-RSRPIRW 357
                + V   L  LL +T +      EG+ +  GL A   +  V  VL  F  R +    
Sbjct: 728  GLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQ 787

Query: 358  SLPSSSPKNSEDLRWKWASSTILLAYGQVAAKARAHIL-PWVDN-IVSRMVFYFHYSSWD 415
            S   S+ +     R +   S +++ Y  VA+     +L   VD+ I ++++ ++  S  D
Sbjct: 788  SWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHHYVSSCQD 847

Query: 416  ETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAM 475
              LK +F+ + + +  A++  +    + F Q + L   ++ +++ EP D L +  R  AM
Sbjct: 848  ICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAM 907

Query: 476  HIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARER 535
               S L KL+P    E  S+L+     SV +L L                          
Sbjct: 908  EALSHLSKLKPFYSTEENSELMDISIHSVISLQLPG------------------------ 943

Query: 536  AGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLA 595
                            +E +++LY+  + +L+ +++SL+ +      L  ++  L  W+ 
Sbjct: 944  --------------EDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWIL 989

Query: 596  SEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLE 655
            SEK  ER++AV   + L++   H+  +       + G +VG++     D  + T+  S+ 
Sbjct: 990  SEKEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMN 1049

Query: 656  GASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIF 715
              S L  L                    SQ  S    LW    QK       ++    + 
Sbjct: 1050 VLSSLLDL------------------HASQTCS----LWGPSKQKELEKCKGDLQSTDVE 1087

Query: 716  QL--CSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLE 773
            ++   S ++ K +  + +  E+  LI    +  G+ +    +A+   +   +Q    +LE
Sbjct: 1088 KIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELE 1147

Query: 774  I-VSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLW 832
              V+ +  AI + L  V  P+ +   +  I LLA  H   ++ + L   +P++SH  ++W
Sbjct: 1148 DKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVW 1207

Query: 833  RALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFARE 892
             A+    P +  +L +L+  LQ R  P  ++ S      K  +  LAA++ L  L     
Sbjct: 1208 LAVSENVPFARTMLHSLMGRLQSRLSPRISATS------KADIWRLAAVDPLMTLCTIHL 1261

Query: 893  FKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQP-------KQQAQEAAVPSPQSCSTSL 945
              Q + E         L  + Y L L L S  +P       K        P P+  +   
Sbjct: 1262 LIQKLDEN--DKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQR 1319

Query: 946  EALKS--LLSTTGHWHDFAH-LELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVL 1002
              +KS  LL         AH L+ Q  W+L     T+ +GV LLAR  +Q+       + 
Sbjct: 1320 VTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLA 1379

Query: 1003 RQLLPSLQSPQERERKVAILILTKFLYSPVLL-EVLPKQAALTVLAQGLHDPSPEVRVLS 1061
              +L  + S     R  +  +  +F+  PVL  E L K AAL +      +    +RVLS
Sbjct: 1380 ELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLS 1439

Query: 1062 LQGLSNILFHPDKGS------LLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQG 1115
            L+ L N+     K        LL+  L PL +     S+ V    M  ++  L  L    
Sbjct: 1440 LRALGNMALGAPKKVKQYRKVLLEKCLGPLREPV---SNSVTAEGMEALTKILAELREGD 1496

Query: 1116 TGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLH 1175
             GS    ++   R FF++E + +R  A  LFG L   +   +    + +V ++ +PL+LH
Sbjct: 1497 VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH 1556

Query: 1176 LKDQCPAVATQAKFTFYRCAVLLRWRLLH--TLFCTLAWERGLSARHFLWTCLMTRSQEE 1233
             +D C   A     T ++C     W+ L   +     A +  ++        ++TR +  
Sbjct: 1557 SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPA 1616

Query: 1234 FSIH-LSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAVDTNLLFRTFEHLRS 1292
                 L + ++Y+ ++   I+       G  +    Q     L  +D   L  + + L+ 
Sbjct: 1617 VLYRFLLETMAYVKNNLSRIRIAACNLAGIIM---KQMSTHYLKKLDFPALRNSLQELQL 1673

Query: 1293 DPEPSIREFATSQLSFLQKVS 1313
            DP+P +R  A   L+ L   S
Sbjct: 1674 DPDPGVRRAALETLTVLDSCS 1694



 Score = 38.9 bits (89), Expect = 0.033
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 2/102 (1%)

Query: 112 IKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLA 171
           I   A   P +V+ T+    +  PEIS++ K  ++  L+ +I     LEE   +    +A
Sbjct: 99  IMEKATTEPSVVINTLIRC-LQVPEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIA 157

Query: 172 LENMTKATELEDIYQ-DAASNMLVAICRHSWRVVAQHLETEL 212
            + M +  E+E   + + AS+ LVA+ R+ + +V   L+  L
Sbjct: 158 SKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHL 199


>gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1710

 Score =  206 bits (524), Expect = 1e-52
 Identities = 255/1105 (23%), Positives = 444/1105 (40%), Gaps = 105/1105 (9%)

Query: 240  DKACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQA 299
            D+  WE++LIQ    S+       WS  L   L     +    S EK FL+   G  L  
Sbjct: 668  DQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLAT 727

Query: 300  EKNGATVRRHLQALL-ETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFG-RSRPIRW 357
                + V   L  LL +T +      EG+ +  GL A   +  V  VL  F  R +    
Sbjct: 728  GLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQ 787

Query: 358  SLPSSSPKNSEDLRWKWASSTILLAYGQVAAKARAHIL-PWVDN-IVSRMVFYFHYSSWD 415
            S   S+ +     R +   S +++ Y  VA+     +L   VD+ I ++++ ++  S  D
Sbjct: 788  SWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHHYVSSCQD 847

Query: 416  ETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAM 475
              LK +F+ + + +  A++  +    + F Q + L   ++ +++ EP D L +  R  AM
Sbjct: 848  ICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAM 907

Query: 476  HIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARER 535
               S L KL+P    E  S+L+     SV +L L                          
Sbjct: 908  EALSHLSKLKPFYSTEENSELMDISIHSVISLQLPG------------------------ 943

Query: 536  AGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLA 595
                            +E +++LY+  + +L+ +++SL+ +      L  ++  L  W+ 
Sbjct: 944  --------------EDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWIL 989

Query: 596  SEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLE 655
            SEK  ER++AV   + L+    H+  +       + G +VG++     D  + T+  S+ 
Sbjct: 990  SEKEWEREKAVSLHLYLMWIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMN 1049

Query: 656  GASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIF 715
              S L  L                    SQ  S    LW    QK       ++    + 
Sbjct: 1050 VLSSLLDL------------------HASQTCS----LWGPSKQKELEKCKGDLQSTDVE 1087

Query: 716  QL--CSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLE 773
            ++   S ++ K +  + +  E+  LI    +  G+ +    +A+   +   +Q    +LE
Sbjct: 1088 KIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIAFFLQMRAKELE 1147

Query: 774  I-VSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLW 832
              V+ +  AI + L  V  P+ +   +  I LLA  H   ++ + L   +P++SH  ++W
Sbjct: 1148 DKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVW 1207

Query: 833  RALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFARE 892
             A+    P +  +L +L+  LQ R  P  ++ S      K  +  LAA++ L  L     
Sbjct: 1208 LAVSENVPFARTMLHSLMGRLQSRLSPRISATS------KADIWRLAAVDPLMTLCTIHL 1261

Query: 893  FKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQP-------KQQAQEAAVPSPQSCSTSL 945
              Q + E         L  + Y L L L S  +P       K        P P+  +   
Sbjct: 1262 LIQKLDEN--DKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHTTPLPEEMNLQR 1319

Query: 946  EALKS--LLSTTGHWHDFAH-LELQGSWELFTTIHTYPKGVGLLARAMVQN----HCRQI 998
              +KS  LL         AH L+ Q  W+L     T+ +GV LLAR  +Q+      R  
Sbjct: 1320 VTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLA 1379

Query: 999  PAVLRQLLPSLQSPQERERKVAILILTKFLYSPVLL-EVLPKQAALTVLAQGLHDPSPEV 1057
              VLR +   + S +     V + +  +F+  PVL  E L K AAL +      +    +
Sbjct: 1380 ELVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLEKGADQEEDEAL 1439

Query: 1058 RVLSLQGLSNILFHPDKGS------LLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRL 1111
            RVLSL+ L N+     K        LL+  L PL +     S+ V    M  ++  L  L
Sbjct: 1440 RVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPV---SNSVTAEGMEALTKILAEL 1496

Query: 1112 GAQGTGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVP 1171
                 GS    ++   R FF++E + +R  A  LFG L   +   +    + +V ++ +P
Sbjct: 1497 REGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIP 1556

Query: 1172 LLLHLKDQCPAVATQAKFTFYRCAVLLRWRLLH--TLFCTLAWERGLSARHFLWTCLMTR 1229
            L+LH +D C   A     T ++C     W+ L   +     A +  ++        ++TR
Sbjct: 1557 LMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMTVFQTTMCSILTR 1616

Query: 1230 SQEEFSIH-LSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAVDTNLLFRTFE 1288
             +       L + ++Y+ ++   I+       G  +    Q     L  +D   L  + +
Sbjct: 1617 KKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIM---KQMSTHYLKKLDFPALRNSLQ 1673

Query: 1289 HLRSDPEPSIREFATSQLSFLQKVS 1313
             L+ DP+P +R  A   L+ L   S
Sbjct: 1674 ELQLDPDPGVRRAALETLTVLDSCS 1698



 Score = 38.9 bits (89), Expect = 0.033
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 2/102 (1%)

Query: 112 IKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLA 171
           I   A   P +V+ T+    +  PEIS++ K  ++  L+ +I     LEE   +    +A
Sbjct: 99  IMEKATTEPSVVINTLIRC-LQVPEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIA 157

Query: 172 LENMTKATELEDIYQ-DAASNMLVAICRHSWRVVAQHLETEL 212
            + M +  E+E   + + AS+ LVA+ R+ + +V   L+  L
Sbjct: 158 SKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHL 199


>gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1723

 Score =  202 bits (513), Expect = 2e-51
 Identities = 247/1117 (22%), Positives = 439/1117 (39%), Gaps = 119/1117 (10%)

Query: 240  DKACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQA 299
            D+  WE++LIQ    S+       WS  L   L     +    S EK FL+   G  L  
Sbjct: 671  DQKAWEDKLIQFLRNSLKKTRGSSWSLRLSKELNNQIASFDSPSLEKGFLYRALGFTLAT 730

Query: 300  EKNGATVRRHLQALL-ETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFG-RSRPIRW 357
                + V   L  LL +T +      EG+ +  GL A   +  V  VL  F  R +    
Sbjct: 731  GLEASKVEVLLLELLYKTDYSNDFDSEGVIMCFGLCARGQVKTVLNVLHDFEERIQESEQ 790

Query: 358  SLPSSSPKNSEDLRWKWASSTILLAYGQVAAKARAHIL-PWVDN-IVSRMVFYFHYSSWD 415
            S   S+ +     R +   S +++ Y  VA+     +L   VD+ I ++++ ++  S  D
Sbjct: 791  SWQISAWRKDHPWRRETVKSALMVMYSCVASYCHPQLLLNLVDSPITAKIIHHYVSSCQD 850

Query: 416  ETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAM 475
              LK +F+ + + +  A++  +    + F Q + L   ++ +++ EP D L +  R  AM
Sbjct: 851  ICLKMAFMKSVVQVTKAINNIKDLEDFHFAQKTTLTSIIVAVIKAEPTDNLVSPVRALAM 910

Query: 476  HIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARER 535
               S L KL+P    E  S+L+     SV +L L                          
Sbjct: 911  EALSHLSKLKPFYSTEENSELMDISIHSVISLQLPG------------------------ 946

Query: 536  AGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLA 595
                            +E +++LY+  + +L+ +++SL+ +      L  ++  L  W+ 
Sbjct: 947  --------------EDNESIKTLYANALSSLEQLMESLLQRQLDPKGLQEMVQLLEKWIL 992

Query: 596  SEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLE 655
            SEK  ER++AV   + L++   H+  +       + G +VG++     D  + T+  S+ 
Sbjct: 993  SEKEWEREKAVSLHLYLMRIYVHSTAVCIHLKLGQFGTMVGLIAPCTCDAHQRTRMASMN 1052

Query: 656  GASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIF 715
              S L  L                    SQ  S    LW    QK       ++    + 
Sbjct: 1053 VLSSLLDL------------------HASQTCS----LWGPSKQKELEKCKGDLQSTDVE 1090

Query: 716  QL--CSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLE 773
            ++   S ++ K +  + +  E+  LI    +  G+ +    +A+   + + +Q    +LE
Sbjct: 1091 KIFCASSRIAKVVCMEFSCDEVVSLIQKLCENTGAMNLQHDKASVTWIASFLQMRAKELE 1150

Query: 774  I-VSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLW 832
              V+ +  AI + L  V  P+ +   +  I LLA  H   ++ + L   +P++SH  ++W
Sbjct: 1151 DKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETILTSLLRQPLPMESHLAEVW 1210

Query: 833  RALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFARE 892
             A+    P +  +L +L+  LQ R  P  ++ S         +  L  +  +H L    +
Sbjct: 1211 LAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLAAVDPLMTLCTIHLLIQKLD 1270

Query: 893  FKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQPKQQAQEAAVPSP-------QSCSTSL 945
                + +  P L   LL Q+      + P    P  +  +    +P       Q CS   
Sbjct: 1271 ENDKLPDFLPDLIYTLLLQLG---SSHRPEAAPPVLKMWKLVHTTPLPEEMNLQRCSRGR 1327

Query: 946  EALKS--LLSTTGHWHDFAH-LELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVL 1002
              +KS  LL         AH L+ Q  W+L     T+ +GV LLAR  +Q+       + 
Sbjct: 1328 VTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCMQHVEGHRQRLA 1387

Query: 1003 RQLLPSLQSPQERERKVAILILTKFLYSPVLL-EVLPKQAALTVLAQGLHDPSPEVRVLS 1061
              +L  + S     R  +  +  +F+  PVL  E L K AAL +      +    +RVLS
Sbjct: 1388 ELVLRGMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLEKGADQEEDEALRVLS 1447

Query: 1062 LQGLSNILFHPDKGS------LLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQG 1115
            L+ L N+     K        LL+  L PL +     S+ V    M  ++  L  L    
Sbjct: 1448 LRALGNMALGAPKKVKQYRKVLLEKCLGPLREPV---SNSVTAEGMEALTKILAELREGD 1504

Query: 1116 TGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLH 1175
             GS    ++   R FF++E + +R  A  LFG L   +   +    + +V ++ +PL+LH
Sbjct: 1505 VGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKGEVKKAWIPLMLH 1564

Query: 1176 LKDQCPAVATQAKFTFYRCAVLLRWR------------------LLHTLFCTLAWERGL- 1216
             +D C   A     T ++C     W+                  +  T  C++   +   
Sbjct: 1565 SQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTTDDKMTIFQTTMCSILVRKPKG 1624

Query: 1217 SARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLN 1276
               H     ++ R       ++   LS +   +C++   +            Q     L 
Sbjct: 1625 EPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGIIM----------KQMSTHYLK 1674

Query: 1277 AVDTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVS 1313
             +D   L  + + L+ DP+P +R  A   L+ L   S
Sbjct: 1675 KLDFPALRNSLQELQLDPDPGVRRAALETLTVLDSCS 1711



 Score = 38.9 bits (89), Expect = 0.033
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 2/102 (1%)

Query: 112 IKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLA 171
           I   A   P +V+ T+    +  PEIS++ K  ++  L+ +I     LEE   +    +A
Sbjct: 99  IMEKATTEPSVVINTLIRC-LQVPEISTQRKVNIYNILQDIIQQEGELEEQCVQRLVAIA 157

Query: 172 LENMTKATELEDIYQ-DAASNMLVAICRHSWRVVAQHLETEL 212
            + M +  E+E   + + AS+ LVA+ R+ + +V   L+  L
Sbjct: 158 SKEMREIPEMEGYMKAEVASDTLVALSRNHFSLVMYELQHHL 199


>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
          Length = 1585

 Score =  196 bits (498), Expect = 1e-49
 Identities = 251/1102 (22%), Positives = 441/1102 (40%), Gaps = 133/1102 (12%)

Query: 244  WEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAEKNG 303
            WE  L+Q+  +S+  +S   W+ +L         +    S EK FL+   G  L   ++ 
Sbjct: 570  WETMLLQLLKESLWKISDVAWTIQLTQDFKQQMGSYSNNSTEKKFLWKALGTTLACCQDS 629

Query: 304  ATVRRHLQALLETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLPSSS 363
              V   ++  L   +Q   QR+G+   LG  A  HLD V  VL  F        +   S 
Sbjct: 630  DFVNSQIKEFLTAPNQLGDQRQGITSILGYCAENHLDIVLKVLKTFQNQEKFFMNRCKSL 689

Query: 364  PKNSEDLRWKWASSTILLAYGQVAAKA-RAHILPWVDNIVSRMVFYFH----------YS 412
                + L      + +++ YG VA  A +  +L  ++  +   V   H            
Sbjct: 690  FSGKKSL----TKTDVMVIYGAVALHAPKKQLLSRLNQDIISQVLSLHGQCSQVLGMSVM 745

Query: 413  SWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQ 472
            + D  L+ SF T ++  +G   +      ++F     L+  ++  +  EP D+L +  R 
Sbjct: 746  NKDMDLQMSF-TRSITEIGIAVQDAEDQGFQFSYKEMLIGYMLDFIRDEPLDSLASPIRW 804

Query: 473  QAMHIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVA 532
            +A+     L KL+P + L+    +L    R +  LP L+ L+                  
Sbjct: 805  KALIAIRYLSKLKPQLSLQDHLNILEENIRRLLPLPPLENLKSE---------------- 848

Query: 533  RERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYI 592
                G T +           EH+Q LY R+M+AL  +L++++  N  A++   + + L +
Sbjct: 849  ----GQTDKD---------KEHIQFLYERSMDALGKLLKTMMWDNVNAEDCQEMFNLLQM 895

Query: 593  WLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRC 652
            WL S+K  ER+RA     I  K L ++  ++  E+FK IG L+G+L     D     ++ 
Sbjct: 896  WLVSQKEWERERAFQ---ITAKVLTND--IEAPENFK-IGSLLGLLAPHSCDTLPTIRQA 949

Query: 653  SLEGASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKN 712
            +      L+ +   H   E LQ                              G QE  ++
Sbjct: 950  AASSTIGLFYIKGIHLEVERLQ------------------------------GLQEGLES 979

Query: 713  HIFQL---CSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHG 769
               Q+    S ++ K + + +   E+   +   +DGL S +P   +A    ++T +++ G
Sbjct: 980  DDVQVQIKISSKIAKIVSKFIPNEEILMFLEEMLDGLESLNPTCTKACGIWMITVLKQQG 1039

Query: 770  AKLEIVSSMAQAIRLRLCSVHIPQAKEKT----LHAITLLARSHTCELVATFLNISIPLD 825
            A LE    + + +      + + + KE++    L AI+ +A  H   +V   L   +P D
Sbjct: 1040 AALE--DQLLEILGTIYHHMPVLRQKEESFQFILEAISQIASFHMDTVVVNLLQKPLPFD 1097

Query: 826  SHTFQLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLH 885
              T  LW+AL     +S  +L  L+  L+     T   D          +  + A+++  
Sbjct: 1098 RDTKTLWKALAEKPASSGKLLQALIDKLE-----TELEDD---------IARVEAISVAC 1143

Query: 886  ELQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEP-----QPKQQAQEAAVPSPQS 940
             +        +V   YP+LF  LL  +   L   + + P        QQ ++  +P P  
Sbjct: 1144 AMYEVISMGTSVTGLYPELFTLLLKLVSCTLGQKMLTCPWSHRRHVMQQGEQQQIPDPCR 1203

Query: 941  CSTS-LEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIP 999
             ST+ L+ L++     G   +    E    W L ++  T+  GV  LAR+M       I 
Sbjct: 1204 LSTATLKCLQAQAMREGLAKESD--EGDNLWTLLSSPSTHHIGVCSLARSMAVWQHGVIL 1261

Query: 1000 AVLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRV 1059
             ++ QLL SL S  E  R       ++ +  P+L +    +  L ++ Q   D +  +R 
Sbjct: 1262 DIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLILMDQSAWDSNATLRQ 1321

Query: 1060 LSLQGLSNILFH-PDKGSL-LQGQLRPLLDGFFQSSDQVIVC-IMGTVSDTLHRLGAQGT 1116
            ++++GL N     P K     Q  L  ++ G +  +   +VC  +  +   L  L  +  
Sbjct: 1322 MAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDV 1381

Query: 1117 GSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHL 1176
                  + + TR+FF DE+D +R  A+ LF DL      R       ++ +S++  LLHL
Sbjct: 1382 SFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHL 1441

Query: 1177 KDQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSI 1236
             D  P +    +     C   L  + L+ +   L  +    AR F           +F +
Sbjct: 1442 WDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLPRARDF---------YRQFCV 1492

Query: 1237 HLS----QALSYLHSHS--CHIKTWVTL---FIGHTICYHPQAVFQMLNAVDTNLLFRTF 1287
             L+    + L  LH+HS      TW  +    +  T         Q +  +D   L    
Sbjct: 1493 KLAKKNQEILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVELLDREQLTTRL 1552

Query: 1288 EHLRSDPEPSIREFATSQLSFL 1309
            + LR DP  S++  A + L  L
Sbjct: 1553 QALRQDPCISVQRAAEAALQTL 1574


>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
          Length = 719

 Score =  159 bits (403), Expect = 1e-38
 Identities = 173/608 (28%), Positives = 259/608 (42%), Gaps = 37/608 (6%)

Query: 721  QVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEI-VSSMA 779
            QV +   ++  LA+L+      ++  G       QA    L +A++  G +LE  V ++ 
Sbjct: 98   QVPQSSWEEGVLADLALYTAACLEEAGFAG---TQATVLTLSSALEARGERLEDQVHALV 154

Query: 780  QAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQ 839
            + +  ++ S+   +     L  ++ LA  H  ++V   L  S+P D    +LWR+L   Q
Sbjct: 155  RGLLAQVPSLAEGRPWRAALRVLSALALEHARDVVCALLPRSLPADRVAAELWRSLSRNQ 214

Query: 840  PTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQE 899
              +  VL  LL  L+      GAS   P        + LAA   L E+        A + 
Sbjct: 215  RVNGQVLVQLLWALK------GASGPEP--------QALAATRALGEMLAVSGCVGATRG 260

Query: 900  GYPKLFLALLTQMHYVLELNLPSEPQ-PKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHW 958
             YP L LAL+TQ+H +     P  P  PK        P     S ++EALK+LL+  G  
Sbjct: 261  FYPHLLLALVTQLHKLARS--PCSPDMPKIWVLSHRGPPHSHASCAVEALKALLTGDGGR 318

Query: 959  HDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERK 1018
                 +E  G W      HT+ +GV LLA AMV +    +  +   LLP L+S  + +R 
Sbjct: 319  MVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRGLFADLLPRLRSADDPQRL 378

Query: 1019 VAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLL 1078
             A+   T  L S     +L ++  L  L     DP P VR L L GL ++  +  K   +
Sbjct: 379  TAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWLGLLGLGHLALNRRKVRHV 438

Query: 1079 QGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQ-GTGSQSLGVAISTRSFFNDERDG 1137
               L  LL    +   +++   +G +   L R  A     S  LG  +      +D RD 
Sbjct: 439  STLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSAELGPRLP--PLLDDTRDS 496

Query: 1138 IRAAAMALFGDLVAAMADRELSG----LRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYR 1193
            IRA+A+ L G LV         G    LR  V QS+VPLLL L D     A  +++T  R
Sbjct: 497  IRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLAR 556

Query: 1194 CAVLLRWRLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIK 1253
            C     W LL  L  T+A      A   L   L+ R        LSQ   YL S    ++
Sbjct: 557  CDHAFCWGLLEEL-VTVAHYDSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLR 615

Query: 1254 TWVTLFIGHTICY-HPQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFA---TSQLSFL 1309
                + IG  + +  P  V Q L     + LF+    L+SDP+P++   A     Q++ L
Sbjct: 616  RAAAVLIGFLVHHASPGCVNQDL----LDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAML 671

Query: 1310 QKVSARPK 1317
             +    P+
Sbjct: 672  ARARGCPR 679


>gi|47578111 hypothetical protein LOC140699 isoform 2 [Homo sapiens]
          Length = 608

 Score =  111 bits (278), Expect = 4e-24
 Identities = 110/470 (23%), Positives = 199/470 (42%), Gaps = 61/470 (12%)

Query: 398 VDNIVSRMVFYFHYSSWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVL 457
           V+ ++  +   F+     E  K  FL     L  A+   E A S+     ++++  L VL
Sbjct: 169 VEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVL 228

Query: 458 MEKEPQDTLCTRSRQQAMHIASSLC--KLRPPIDLERKSQLLSTCFRSVFALPLLDALEK 515
           +++E   +L +  RQ+     + L    +   +  E +++L S   +S+  LP +  L +
Sbjct: 229 VQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQ 288

Query: 516 HTCLFLEPPNIQLWPVARERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIM 575
              +    PN                            + + LY +T +A   MLQSL++
Sbjct: 289 IQEIM---PNGTC-------------------------NTECLYRQTFQAFSEMLQSLVV 320

Query: 576 QNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLV 635
           ++P  + L  ++ HL  WL S K HER+RA  S   +LK L+ +  L     F+R+G LV
Sbjct: 321 KDPHLENLDTIIKHLVPWLQSVKDHERERATASMAQVLKCLSKHLNLKLPLRFQRLGHLV 380

Query: 636 GILGMLCQDPDRATQRCSLEGASHLYQLLM-------CHKTGEALQAESQAPKELSQAHS 688
            ++ +LC DP       + EG   L  + +         K  + L+      +E  + HS
Sbjct: 381 ALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHS 440

Query: 689 DGAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGS 748
             A                       F  C F++ +     L   EL   I T  D L +
Sbjct: 441 SAA---------------------KCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKT 479

Query: 749 TS-PFRVQAASEMLLTAVQEHGAKLEIVSSMAQAIRLRLCSVHIPQAKEKTLHAITL-LA 806
              P   ++A E+LLT  +   ++ E V  +   I  +L  +  P+ +++ ++ ++L ++
Sbjct: 480 LKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFIS 539

Query: 807 RSHTCELVATFLNI-SIPLDSHTFQLWRALGAGQPTSHLVLTTLLACLQE 855
           R    ++V +FL    +P + H  ++WR L    P++  +L  LL  LQ+
Sbjct: 540 RPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQK 589


>gi|117956387 hypothetical protein LOC80133 [Homo sapiens]
          Length = 573

 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 103/474 (21%), Positives = 198/474 (41%), Gaps = 41/474 (8%)

Query: 553  EHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMIL 612
            E +++LY   +   + +L SL+ ++    ++   L  + +W++ + ++ ++R +     +
Sbjct: 93   EDMENLYHNILNIYENILTSLVSKDLYKLQI---LKEMLVWMSKDSSYLQERIMVIINKV 149

Query: 613  LKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLEGASHLYQLLMCHKTGEA 672
            L+F           D   +G L   L +LC   D +  + +  G  HL  +  C      
Sbjct: 150  LRFTVTKVRKYISVDAPCLGLLAAELSLLCSHEDPSIVKQASLGMCHLLYIARCQNDIGT 209

Query: 673  LQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTL 732
             +  +     L    SD   L            P+E      FQ    ++ + + Q L  
Sbjct: 210  NKPTNGKSHSLQFPSSDVEFL------------PKE------FQQDESKIAQRVGQTLLP 251

Query: 733  AELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEIVSSMAQAIRLRLCSVHIP 792
              L+D + + +  L S        A+ +L+  ++ H  K+ +VS +  AI  +LC  +  
Sbjct: 252  PLLTDFVQSLLMKLSSPDDKIASDAASILIFTLEFHAEKVTMVSKIVDAIYRQLCDNNC- 310

Query: 793  QAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQPTSHLVLTTLLAC 852
              K+  L  ITLL  +   +++   ++  +P D    Q+W+A  +    +  VL T+L  
Sbjct: 311  -MKDVMLQVITLLTCTSPKKVIFQLMDYPVPADDTLIQMWKAACSQASVAPHVLKTILLI 369

Query: 853  LQERP--LPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEGYPKLFLALLT 910
            L+ +P  +    ++      + T L  LAA   L        +++AV + +P+L   L+ 
Sbjct: 370  LKGKPGEMEDTVTEGKRFSLDITNLMPLAACQALCTFLPLGSYRKAVAQYFPQLLTTLMF 429

Query: 911  QMHYVLELNLPSEPQPKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHWHDFAHLELQGSW 970
            Q+ Y  EL    +P  K +A  A            +AL+ LL+ +G       L  +  W
Sbjct: 430  QVFYNSEL----KPILKDRALYAQ-----------DALRVLLNCSGLQQVDITLMKENFW 474

Query: 971  ELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLP-SLQSPQERERKVAILI 1023
            +  +    Y  GV  +A+ + + +  Q P  L  L   S++ P+  E  V +LI
Sbjct: 475  DQLSEDLCYYHGVCFIAKTLSEYNFPQFPETLSYLYKLSVEGPRRSEDTVIVLI 528


>gi|187761375 maestro isoform a [Homo sapiens]
          Length = 248

 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 57/202 (28%), Positives = 99/202 (49%), Gaps = 3/202 (1%)

Query: 1001 VLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVL 1060
            +L Q L    S  +++R   I   +K  +     +  P +    +LA+   DPS + R +
Sbjct: 8    ILGQPLSIPTSQPKQKRTSMISFFSKVSWKLRFQKREPLKNVFFILAERARDPSAKKRHM 67

Query: 1061 SLQGLSNILFH-PDKGSLLQGQLRPLLD-GFFQSSD-QVIVCIMGTVSDTLHRLGAQGTG 1117
            +++ L  + +  PDK    +  +  LL  G +   + +VI   M T++  L ++  +G G
Sbjct: 68   AMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLG 127

Query: 1118 SQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLK 1177
            S  + + + TR+  +DE D +R +A  LFG L A    +      +QV Q+   LL+HL+
Sbjct: 128  SFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQ 187

Query: 1178 DQCPAVATQAKFTFYRCAVLLR 1199
            D+ P VA   K TF  C+  L+
Sbjct: 188  DRNPQVAKACKTTFQACSPYLK 209


>gi|187761381 maestro isoform d [Homo sapiens]
          Length = 262

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 50/165 (30%), Positives = 85/165 (51%), Gaps = 3/165 (1%)

Query: 1038 PKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFH-PDKGSLLQGQLRPLLD-GFFQSSD- 1094
            P +    +LA+   DPS + R ++++ L  + +  PDK    +  +  LL  G +   + 
Sbjct: 59   PLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNL 118

Query: 1095 QVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMA 1154
            +VI   M T++  L ++  +G GS  + + + TR+  +DE D +R +A  LFG L A   
Sbjct: 119  EVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAG 178

Query: 1155 DRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLR 1199
             +      +QV Q+   LL+HL+D+ P VA   K TF  C+  L+
Sbjct: 179  RKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLK 223


>gi|47578113 hypothetical protein LOC140699 isoform 3 [Homo sapiens]
          Length = 573

 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 95/470 (20%), Positives = 182/470 (38%), Gaps = 96/470 (20%)

Query: 398 VDNIVSRMVFYFHYSSWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVL 457
           V+ ++  +   F+     E  K  FL     L  A+   E A S+     ++++  L VL
Sbjct: 169 VEKLIQSIQKVFNGELKGELEKLKFLGDLSSLSQALPYDETAKSFIHSHIADIVHTLNVL 228

Query: 458 MEKEPQDTLCTRSRQQAMHIASSLC--KLRPPIDLERKSQLLSTCFRSVFALPLLDALEK 515
           +++E   +L +  RQ+     + L    +   +  E +++L S   +S+  LP +  L +
Sbjct: 229 VQEERPHSLSSSMRQEVFVTIADLSYQDVHLLLGSEDRAELFSLTIKSIITLPSVRTLTQ 288

Query: 516 HTCLFLEPPNIQLWPVARERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIM 575
              +    PN                            + + LY +T +A   MLQSL++
Sbjct: 289 IQEIM---PNGTC-------------------------NTECLYRQTFQAFSEMLQSLVV 320

Query: 576 QNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLV 635
           ++P  + L  ++                       + L+F             +R+G LV
Sbjct: 321 KDPHLENLDTIIK----------------------LPLRF-------------QRLGHLV 345

Query: 636 GILGMLCQDPDRATQRCSLEGASHLYQLLM-------CHKTGEALQAESQAPKELSQAHS 688
            ++ +LC DP       + EG   L  + +         K  + L+      +E  + HS
Sbjct: 346 ALMALLCGDPQEKVAEEAAEGIHSLLHITLRLKYITHDKKDQQNLKRALTKCREFLELHS 405

Query: 689 DGAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGS 748
             A                       F  C F++ +     L   EL   I T  D L +
Sbjct: 406 SAA---------------------KCFYNCPFRIAQVFEGFLDSNELCQFIMTTFDTLKN 444

Query: 749 TS-PFRVQAASEMLLTAVQEHGAKLEIVSSMAQAIRLRLCSVHIPQAKEKTLHAITL-LA 806
              P   ++A E+LLT  +   ++ E V  +   I  +L  +  P+ +++ ++ ++L ++
Sbjct: 445 LKHPCIQRSAGELLLTLAKNTESQFEKVPEIMGVICAQLSIISQPRVRQQIINTVSLFIS 504

Query: 807 RSHTCELVATFLNI-SIPLDSHTFQLWRALGAGQPTSHLVLTTLLACLQE 855
           R    ++V +FL    +P + H  ++WR L    P++  +L  LL  LQ+
Sbjct: 505 RPKYTDIVLSFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQK 554


>gi|149944578 HEAT repeat containing 7A isoform 2 [Homo sapiens]
          Length = 422

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 1/139 (0%)

Query: 93  MLQDMNSADPFHLKYIIKKIKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMV 152
           +L  +   DP   + +   + ++    P   +    +Y   + +++  ++  + + +E V
Sbjct: 13  LLDAITDKDPLVQEQVCSALCSLGEVRPVETLRACEEYLRQHDKLAHPYRAAVLRAMERV 72

Query: 153 IGA-SDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQHLETE 211
           + + +  L++    T   LA   MTK  +L   +Q AAS +LVA+ R     V + L   
Sbjct: 73  LSSRASELDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRR 132

Query: 212 LLTGVFPHRSLLYVMGVLS 230
           L  G  PH ++L+ +  LS
Sbjct: 133 LHPGTLPHCAVLHTLASLS 151


>gi|149944469 HEAT repeat containing 7A isoform 2 [Homo sapiens]
          Length = 422

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 1/139 (0%)

Query: 93  MLQDMNSADPFHLKYIIKKIKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMV 152
           +L  +   DP   + +   + ++    P   +    +Y   + +++  ++  + + +E V
Sbjct: 13  LLDAITDKDPLVQEQVCSALCSLGEVRPVETLRACEEYLRQHDKLAHPYRAAVLRAMERV 72

Query: 153 IGA-SDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQHLETE 211
           + + +  L++    T   LA   MTK  +L   +Q AAS +LVA+ R     V + L   
Sbjct: 73  LSSRASELDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRR 132

Query: 212 LLTGVFPHRSLLYVMGVLS 230
           L  G  PH ++L+ +  LS
Sbjct: 133 LHPGTLPHCAVLHTLASLS 151


>gi|187761377 maestro isoform b [Homo sapiens]
          Length = 196

 Score = 33.1 bits (74), Expect = 1.8
 Identities = 32/136 (23%), Positives = 64/136 (47%), Gaps = 3/136 (2%)

Query: 1001 VLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVL 1060
            +L Q L    S  +++R   I   +K  +     +  P +    +LA+   DPS + R +
Sbjct: 8    ILGQPLSIPTSQPKQKRTSMISFFSKVSWKLRFQKREPLKNVFFILAERARDPSAKKRHM 67

Query: 1061 SLQGLSNILFH-PDKGSLLQGQLRPLLD-GFFQSSD-QVIVCIMGTVSDTLHRLGAQGTG 1117
            +++ L  + +  PDK    +  +  LL  G +   + +VI   M T++  L ++  +G G
Sbjct: 68   AMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLG 127

Query: 1118 SQSLGVAISTRSFFND 1133
            S  + + + TR+  +D
Sbjct: 128  SFFIDITLQTRTLLDD 143


>gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo
           sapiens]
          Length = 217

 Score = 32.7 bits (73), Expect = 2.4
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 840 PTSHLVLTTLLACLQERPLP-TGASDSSPCPKEKTYLRLLAAMNML 884
           P+ H +LT L+    +R  P +G S  SP PKEK +  LL  ++ L
Sbjct: 163 PSIHPLLTNLVESKSDRATPCSGNSRGSPLPKEKVHAPLLGVVSRL 208


>gi|5032187 transducer of ERBB2, 1 [Homo sapiens]
          Length = 345

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 907 ALLTQMHYVLELNLPSEPQPKQQAQEAAVPSPQSCSTSLEALK-SLLSTTGHWHDFAHLE 965
           A+ + MH +  L L S+ QP+QQ Q A  P P       +  K S LS       F +++
Sbjct: 221 AISSSMHSLYGLGLGSQQQPQQQQQPAQPPPPPPPPQQQQQQKTSALSPNAKEFIFPNMQ 280

Query: 966 LQGS 969
            QGS
Sbjct: 281 GQGS 284


>gi|187761379 maestro isoform c [Homo sapiens]
          Length = 210

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 1038 PKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFH-PDKGSLLQGQLRPLLD-GFFQSSD- 1094
            P +    +LA+   DPS + R ++++ L  + +  PDK    +  +  LL  G +   + 
Sbjct: 59   PLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNL 118

Query: 1095 QVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFND 1133
            +VI   M T++  L ++  +G GS  + + + TR+  +D
Sbjct: 119  EVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD 157


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 8/69 (11%)

Query: 711 KNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDG--LGSTSPFRVQAASEMLLTAVQEH 768
           ++H+FQ+ +F+ +K I  Q     L + I+ AI+G   GS+S F  + + E    A+  +
Sbjct: 309 RDHVFQVNNFEALKTIQNQ-----LREKIF-AIEGTQTGSSSSFEHEMSQEGFSAAITSN 362

Query: 769 GAKLEIVSS 777
           G  L  V S
Sbjct: 363 GPLLSTVGS 371


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 8/69 (11%)

Query: 711 KNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDG--LGSTSPFRVQAASEMLLTAVQEH 768
           ++H+FQ+ +F+ +K I  Q     L + I+ AI+G   GS+S F  + + E    A+  +
Sbjct: 309 RDHVFQVNNFEALKTIQNQ-----LREKIF-AIEGTQTGSSSSFEHEMSQEGFSAAITSN 362

Query: 769 GAKLEIVSS 777
           G  L  V S
Sbjct: 363 GPLLSTVGS 371


>gi|187828635 NOL1/NOP2/Sun domain family, member 7 [Homo sapiens]
          Length = 718

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 4/80 (5%)

Query: 159 LEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQHLETELLTGVFP 218
           L E+ +++F RL+ E    A +    YQD    +L+  C      +  HL + ++  ++ 
Sbjct: 78  LSESEDQSFQRLSYELAFSALK----YQDILETILIDSCIFPSTTIPDHLSSLIIVMLYD 133

Query: 219 HRSLLYVMGVLSSSEELFSQ 238
            +   +   VLS +EE  S+
Sbjct: 134 FQDRKFQTRVLSDNEEPISE 153


>gi|40217810 cell cycle progression 2 protein isoform 2 [Homo
           sapiens]
          Length = 521

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 15/145 (10%)

Query: 147 QTLEMVIGASDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQ 206
           + LE++ G+ D+          RL+     K  +   + QDA  + L+ +       V  
Sbjct: 84  ELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWH 143

Query: 207 HLETELLTGVFPHRSLLYVMGVLSSSEELFSQEDKACWEEQLIQ-----MAIKSVPFLST 261
              ++LL         LY +G+  +S+EL S E +  W  + ++        +S   LS 
Sbjct: 144 GTLSKLLGS-------LYALGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQ 196

Query: 262 DVWSKELLWTLTT---PSWTQQEQS 283
           +  S+ELL  L T     WT+ E S
Sbjct: 197 EQHSQELLAELLTHLERRWTEIEDS 221


>gi|13569848 cell cycle progression 2 protein isoform 2 [Homo
           sapiens]
          Length = 521

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 15/145 (10%)

Query: 147 QTLEMVIGASDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQ 206
           + LE++ G+ D+          RL+     K  +   + QDA  + L+ +       V  
Sbjct: 84  ELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWH 143

Query: 207 HLETELLTGVFPHRSLLYVMGVLSSSEELFSQEDKACWEEQLIQ-----MAIKSVPFLST 261
              ++LL         LY +G+  +S+EL S E +  W  + ++        +S   LS 
Sbjct: 144 GTLSKLLGS-------LYALGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQ 196

Query: 262 DVWSKELLWTLTT---PSWTQQEQS 283
           +  S+ELL  L T     WT+ E S
Sbjct: 197 EQHSQELLAELLTHLERRWTEIEDS 221


>gi|40217812 cell cycle progression 2 protein isoform 1 [Homo
           sapiens]
          Length = 631

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 15/145 (10%)

Query: 147 QTLEMVIGASDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQ 206
           + LE++ G+ D+          RL+     K  +   + QDA  + L+ +       V  
Sbjct: 84  ELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWH 143

Query: 207 HLETELLTGVFPHRSLLYVMGVLSSSEELFSQEDKACWEEQLIQ-----MAIKSVPFLST 261
              ++LL         LY +G+  +S+EL S E +  W  + ++        +S   LS 
Sbjct: 144 GTLSKLLGS-------LYALGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQ 196

Query: 262 DVWSKELLWTLTT---PSWTQQEQS 283
           +  S+ELL  L T     WT+ E S
Sbjct: 197 EQHSQELLAELLTHLERRWTEIEDS 221


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,796,230
Number of Sequences: 37866
Number of extensions: 2178932
Number of successful extensions: 6365
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 6263
Number of HSP's gapped (non-prelim): 47
length of query: 1318
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1204
effective length of database: 13,930,794
effective search space: 16772675976
effective search space used: 16772675976
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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