Guide to the Human Genome
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Search of human proteins with 148664226

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
         (881 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]                 1752   0.0  
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]                 1636   0.0  
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]                   341   2e-93
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ...   341   2e-93
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]                   329   8e-90
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...   278   1e-74
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                    273   4e-73
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                    273   4e-73
gi|6005830 plakophilin 3 [Homo sapiens]                               270   3e-72
gi|4502247 armadillo repeat protein [Homo sapiens]                    243   4e-64
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]               242   1e-63
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]               242   1e-63
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]               242   1e-63
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]               242   1e-63
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]              242   1e-63
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]               242   1e-63
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]               242   1e-63
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]               242   1e-63
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                242   1e-63
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]              242   1e-63
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]              235   1e-61
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]             235   1e-61
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]             235   1e-61
gi|116256455 zinc finger protein 429 [Homo sapiens]                    55   3e-07
gi|224451040 Yip1 interacting factor homolog B isoform 7 [Homo s...    53   1e-06
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]     53   1e-06
gi|144953913 zinc finger protein 714 [Homo sapiens]                    53   1e-06
gi|148277022 selenoprotein P isoform 2 [Homo sapiens]                  43   0.001
gi|59859882 baculoviral IAP repeat-containing protein 5 isoform ...    42   0.002
gi|4759046 RNA polymerase I subunit isoform 2 [Homo sapiens]           42   0.002

>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
          Length = 881

 Score = 1752 bits (4537), Expect = 0.0
 Identities = 881/881 (100%), Positives = 881/881 (100%)

Query: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60
           MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV
Sbjct: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60

Query: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120
           QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE
Sbjct: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120

Query: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180
           GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH
Sbjct: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180

Query: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240
           QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL
Sbjct: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240

Query: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300
           LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT
Sbjct: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300

Query: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360
           LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML
Sbjct: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360

Query: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420
           EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR
Sbjct: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420

Query: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACN 480
           NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACN
Sbjct: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACN 480

Query: 481 PSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 540
           PSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE
Sbjct: 481 PSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 540

Query: 541 GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD 600
           GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD
Sbjct: 541 GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD 600

Query: 601 DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ 660
           DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ
Sbjct: 601 DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ 660

Query: 661 DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV 720
           DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV
Sbjct: 661 DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV 720

Query: 721 AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD 780
           AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD
Sbjct: 721 AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD 780

Query: 781 TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA 840
           TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA
Sbjct: 781 TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA 840

Query: 841 SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 881
           SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD
Sbjct: 841 SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 881


>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
          Length = 837

 Score = 1636 bits (4236), Expect = 0.0
 Identities = 837/881 (95%), Positives = 837/881 (95%), Gaps = 44/881 (4%)

Query: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60
           MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV
Sbjct: 1   MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQV 60

Query: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120
           QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE
Sbjct: 61  QQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYE 120

Query: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180
           GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH
Sbjct: 121 GRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH 180

Query: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240
           QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL
Sbjct: 181 QESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQHGSVSDTVFDSIPANPAL 240

Query: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300
           LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT
Sbjct: 241 LTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRT 300

Query: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360
           LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML
Sbjct: 301 LREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGNADMEMTLERAVSML 360

Query: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420
           EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR
Sbjct: 361 EADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALR 420

Query: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACN 480
           NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQIT                     
Sbjct: 421 NLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQIT--------------------- 459

Query: 481 PSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 540
                                  GLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE
Sbjct: 460 -----------------------GLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE 496

Query: 541 GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD 600
           GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD
Sbjct: 497 GDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPD 556

Query: 601 DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ 660
           DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ
Sbjct: 557 DKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQ 616

Query: 661 DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV 720
           DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV
Sbjct: 617 DVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSV 676

Query: 721 AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD 780
           AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD
Sbjct: 677 AQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD 736

Query: 781 TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA 840
           TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA
Sbjct: 737 TVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAA 796

Query: 841 SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 881
           SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD
Sbjct: 797 SVLLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD 837


>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
          Length = 726

 Score =  341 bits (875), Expect = 2e-93
 Identities = 198/526 (37%), Positives = 300/526 (57%), Gaps = 54/526 (10%)

Query: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290

Query: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350

Query: 459 TDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNL 518
           T                                            GLLWNLSS D+LK  
Sbjct: 351 T--------------------------------------------GLLWNLSSTDELKEE 366

Query: 519 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRR 578
           +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCLRN+SSA A GR+ MR 
Sbjct: 367 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADA-GRQTMRN 425

Query: 579 CDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQ 638
             GLIDSL+ YV+  +A  + DDK+ ENC+C+LHNLSY+L+AE+P +Y Q  Y   RN  
Sbjct: 426 YSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEY-NARNAY 484

Query: 639 TDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYT 698
           T+ + S GCF ++S K+     D P+PEE++NPKG  WL+HS  IR YL+L+ KS ++ T
Sbjct: 485 TEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT 543

Query: 699 QEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSR 758
            EA  GALQNLTA  G M + ++Q +  KE GL    ++L  G+  V ++  SLL N+SR
Sbjct: 544 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 603

Query: 759 NLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGG 818
           +  L   +  +  P++  ++     +T    +  +SACYT+ N++ +  Q A+   ++  
Sbjct: 604 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM 663

Query: 819 IQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKK 864
           +  I+ +      AS KA++AA +LL  +W+  EL    ++  F +
Sbjct: 664 LNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGFDR 707



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)

Query: 13  IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
           ++T L  +     D+S+LALPS+ K+K  G+SGR        R+QEQV  T+ R+   S 
Sbjct: 6   LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57

Query: 73  GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
            +  L  ++    Y      + +++  G +     Y   +AG      G WG     GT 
Sbjct: 58  QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108

Query: 128 ------AQYSSQKSVEERSLRHP 144
                  ++SS   +E  S  +P
Sbjct: 109 KREPDNRRFSSYSQMENWSRHYP 131


>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
           sapiens]
          Length = 625

 Score =  341 bits (875), Expect = 2e-93
 Identities = 198/526 (37%), Positives = 300/526 (57%), Gaps = 54/526 (10%)

Query: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 132 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 189

Query: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 190 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 249

Query: 459 TDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNL 518
           T                                            GLLWNLSS D+LK  
Sbjct: 250 T--------------------------------------------GLLWNLSSTDELKEE 265

Query: 519 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRR 578
           +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCLRN+SSA A GR+ MR 
Sbjct: 266 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADA-GRQTMRN 324

Query: 579 CDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQ 638
             GLIDSL+ YV+  +A  + DDK+ ENC+C+LHNLSY+L+AE+P +Y Q  Y   RN  
Sbjct: 325 YSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEY-NARNAY 383

Query: 639 TDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYT 698
           T+ + S GCF ++S K+     D P+PEE++NPKG  WL+HS  IR YL+L+ KS ++ T
Sbjct: 384 TEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT 442

Query: 699 QEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSR 758
            EA  GALQNLTA  G M + ++Q +  KE GL    ++L  G+  V ++  SLL N+SR
Sbjct: 443 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 502

Query: 759 NLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGG 818
           +  L   +  +  P++  ++     +T    +  +SACYT+ N++ +  Q A+   ++  
Sbjct: 503 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM 562

Query: 819 IQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKK 864
           +  I+ +      AS KA++AA +LL  +W+  EL    ++  F +
Sbjct: 563 LNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGFDR 606


>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
          Length = 747

 Score =  329 bits (843), Expect = 8e-90
 Identities = 198/547 (36%), Positives = 300/547 (54%), Gaps = 75/547 (13%)

Query: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
           S++ + D+E   +T+ +AV  L +       I A   +IQH CFQ   A+++V QL GI 
Sbjct: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290

Query: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
           KL+ LL+  N++VQ+A  GALRNLVF    NKLE    NG+   + +L++T + E +KQ+
Sbjct: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350

Query: 459 TDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNL 518
           T                                            GLLWNLSS D+LK  
Sbjct: 351 T--------------------------------------------GLLWNLSSTDELKEE 366

Query: 519 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLR--------------- 563
           +I +AL  L + +IIPFSGW +G+   +  ++D ++F+N TGCLR               
Sbjct: 367 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQR 426

Query: 564 ------NMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQ 617
                 N+SSA A GR+ MR   GLIDSL+ YV+  +A  + DDK+ ENC+C+LHNLSY+
Sbjct: 427 ATSSRVNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYR 485

Query: 618 LEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWL 677
           L+AE+P +Y Q  Y   RN  T+ + S GCF ++S K+     D P+PEE++NPKG  WL
Sbjct: 486 LDAEVPTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWL 543

Query: 678 WHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKM 737
           +HS  IR YL+L+ KS ++ T EA  GALQNLTA  G M + ++Q +  KE GL    ++
Sbjct: 544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL 603

Query: 738 LHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACY 797
           L  G+  V ++  SLL N+SR+  L   +  +  P++  ++     +T    +  +SACY
Sbjct: 604 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACY 663

Query: 798 TLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAY 857
           T+ N++ +  Q A+   ++  +  I+ +      AS KA++AA +LL  +W+  EL    
Sbjct: 664 TVRNLMASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVL 721

Query: 858 KKAQFKK 864
           ++  F +
Sbjct: 722 RQQGFDR 728



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)

Query: 13  IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
           ++T L  +     D+S+LALPS+ K+K  G+SGR        R+QEQV  T+ R+   S 
Sbjct: 6   LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57

Query: 73  GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
            +  L  ++    Y      + +++  G +     Y   +AG      G WG     GT 
Sbjct: 58  QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108

Query: 128 ------AQYSSQKSVEERSLRHP 144
                  ++SS   +E  S  +P
Sbjct: 109 KREPDNRRFSSYSQMENWSRHYP 131


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
            plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score =  278 bits (712), Expect = 1e-74
 Identities = 223/739 (30%), Positives = 343/739 (46%), Gaps = 97/739 (13%)

Query: 163  HSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYHRQYQ 222
            H+  QYS+        H QE    A L  P      +   SRA  +S+  H     R  Q
Sbjct: 367  HASEQYSK--------HSQELYATATLQRP----GSLAAGSRASYSSQHGHLGPELRALQ 414

Query: 223  HGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPVTQ 282
                 +   D I  +      P    S+S G+ L   +  T   +     P V   P+ +
Sbjct: 415  S---PEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQR 471

Query: 283  NRASRSSWHQSSFHSTRTLREAGP-SVAVDSSGRRAHLTVGQAAAGGSGNLLTERSTFTD 341
              +     + ++    R    AGP S   D   +  +    ++    SG  L    T   
Sbjct: 472  TGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLAR 531

Query: 342  S-----------QLGNADMEMTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKR 390
            S           + G  D E  L   + ML+  H  PS  S AA ++QH CF  ++ +  
Sbjct: 532  SPSIDSIQKDPREFGWRDPE--LPEVIQMLQ--HQFPSVQSNAAAYLQHLCFGDNKIKAE 587

Query: 391  VNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQ 448
            + +  GI  L+ LL  +  +V R+ CGALRNLV+   ++DNK+ +    G+P L+++L++
Sbjct: 588  IRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRK 647

Query: 449  TRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWN 508
            T DLE ++ +T                                            G+LWN
Sbjct: 648  TTDLEIRELVT--------------------------------------------GVLWN 663

Query: 509  LSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKANGLLDFDIFYNVTGCLRNM 565
            LSS D LK  +I +AL  LT  +IIP SGW   P  D  K   L    +  N TGCLRN+
Sbjct: 664  LSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQ-LHSSQVLRNATGCLRNV 722

Query: 566  SSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEK 625
            SSAG + R+ MR CDGL D+L++ ++  +   + D K  ENCVCIL NLSY+L AE  + 
Sbjct: 723  SSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQG 782

Query: 626  YSQNIYIQNRNIQTDNN----KSIGCFGSRSRKVKEQYQ---DVPMPEEKSNPKGVEWLW 678
                    +  +  + N    +S GC+G + +K K Q Q     P+P+    PKG++ LW
Sbjct: 783  QHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLW 842

Query: 679  HSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKML 738
            H  +++ YL+L+++     T E + GALQNL AGS      + +  V+KE GL    ++L
Sbjct: 843  HPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYI-RAAVRKEKGLPILVELL 901

Query: 739  HVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIP-----DTVPSTDLLIETTA 793
             + +  V     + LRN++ ++  +  I K  + DLV  +P     +   S  +  +T  
Sbjct: 902  RIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVT 961

Query: 794  SACYTLNNIIQNSYQNARDLLNTGGIQKIMAI--SAGDAYASNKASKAASVLLYSLWAHT 851
            + C TL+ +I  + +NA+ L + GGI+K++ I  S GD + S K  KAAS +L S+W + 
Sbjct: 962  AVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKH-SPKVVKAASQVLNSMWQYR 1020

Query: 852  ELHHAYKKAQFKKTDFVNS 870
            +L   YKK  + +  FV S
Sbjct: 1021 DLRSLYKKDGWSQYHFVAS 1039


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score =  273 bits (699), Expect = 4e-73
 Identities = 176/533 (33%), Positives = 282/533 (52%), Gaps = 67/533 (12%)

Query: 353  LERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQ 412
            L   + ML+  H  PS  + AA ++QH CF  ++ +  V +L GI  L+ LL  +  +VQ
Sbjct: 530  LPEVIHMLQ--HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQ 587

Query: 413  RAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNG 470
            +  CGALRNLVF    ++NK+ +  + G+P LL++L+++ D E ++ +T           
Sbjct: 588  KNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVT----------- 636

Query: 471  WPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTEN 530
                                             G+LWNLSS D +K  +I +AL TLT  
Sbjct: 637  ---------------------------------GVLWNLSSCDAVKMTIIRDALSTLTNT 663

Query: 531  IIIPFSGWPEGDYPKANGLLDFD---IFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLV 587
            +I+P SGW    +   + +  F    +  N TGCLRN+SSAG + RK MR C+GL+DSL+
Sbjct: 664  VIVPHSGWNNSSFDDDHKI-KFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLL 722

Query: 588  HYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNI-----YIQNRNIQTDNN 642
            + +   +     D K  ENCVC L NLSY+LE E+P+     +      +   +   D+ 
Sbjct: 723  YVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSE 782

Query: 643  KSIGCFGSRSRKVK-----EQYQDV-PMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRN 696
             S  C+G + +K K     +Q+  V P+P    +PKGVE LWH  V++ YL+L+A+S   
Sbjct: 783  PS--CWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP 840

Query: 697  YTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNL 756
             T E S G+LQNL+AG+      + +  V+KE GL    ++L + +  V  +  + LRN+
Sbjct: 841  ATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLRMDNDRVVSSVATALRNM 899

Query: 757  SRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNT 816
            + ++  +  I K  + DLV+ +P     + L  ET A+ C  L+ +   + +NA+ L ++
Sbjct: 900  ALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADS 959

Query: 817  GGIQKIMAISAGDAYASN-KASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV 868
            GGI+K++ I+ G    S+ K  KAA+ +L +LW + +L   YKK  + +  F+
Sbjct: 960  GGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFI 1012


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score =  273 bits (699), Expect = 4e-73
 Identities = 176/533 (33%), Positives = 282/533 (52%), Gaps = 67/533 (12%)

Query: 353  LERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQ 412
            L   + ML+  H  PS  + AA ++QH CF  ++ +  V +L GI  L+ LL  +  +VQ
Sbjct: 530  LPEVIHMLQ--HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQ 587

Query: 413  RAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNG 470
            +  CGALRNLVF    ++NK+ +  + G+P LL++L+++ D E ++ +T           
Sbjct: 588  KNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVT----------- 636

Query: 471  WPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTEN 530
                                             G+LWNLSS D +K  +I +AL TLT  
Sbjct: 637  ---------------------------------GVLWNLSSCDAVKMTIIRDALSTLTNT 663

Query: 531  IIIPFSGWPEGDYPKANGLLDFD---IFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLV 587
            +I+P SGW    +   + +  F    +  N TGCLRN+SSAG + RK MR C+GL+DSL+
Sbjct: 664  VIVPHSGWNNSSFDDDHKI-KFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLL 722

Query: 588  HYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNI-----YIQNRNIQTDNN 642
            + +   +     D K  ENCVC L NLSY+LE E+P+     +      +   +   D+ 
Sbjct: 723  YVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSE 782

Query: 643  KSIGCFGSRSRKVK-----EQYQDV-PMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRN 696
             S  C+G + +K K     +Q+  V P+P    +PKGVE LWH  V++ YL+L+A+S   
Sbjct: 783  PS--CWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP 840

Query: 697  YTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNL 756
             T E S G+LQNL+AG+      + +  V+KE GL    ++L + +  V  +  + LRN+
Sbjct: 841  ATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLRMDNDRVVSSVATALRNM 899

Query: 757  SRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNT 816
            + ++  +  I K  + DLV+ +P     + L  ET A+ C  L+ +   + +NA+ L ++
Sbjct: 900  ALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADS 959

Query: 817  GGIQKIMAISAGDAYASN-KASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV 868
            GGI+K++ I+ G    S+ K  KAA+ +L +LW + +L   YKK  + +  F+
Sbjct: 960  GGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFI 1012


>gi|6005830 plakophilin 3 [Homo sapiens]
          Length = 797

 Score =  270 bits (691), Expect = 3e-72
 Identities = 231/863 (26%), Positives = 388/863 (44%), Gaps = 109/863 (12%)

Query: 29  SLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVY 88
           SLALPS+ +L   G+ G   + +++ R+QEQV+  L + G+    NG     ++ PE   
Sbjct: 19  SLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQPRHNG-----AAEPE--- 70

Query: 89  NLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRL 148
                E +   G S     Y  L+AG ++  +G  G  T+ +             P+ + 
Sbjct: 71  ----PEAETARGTSR--GQYHTLQAGFSSRSQGLSGDKTSGF------------RPIAKP 112

Query: 149 EISPDSSPERAHYTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTT 208
             SP S   R+    S  +    +  G +         A   PP   R   V     G  
Sbjct: 113 AYSPASWSSRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRP--VSFHERGGV 170

Query: 209 SRQRHFDTYHRQY----------QHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEK 258
             +  +DT   +           ++  VS+ +  +  +      Y R  +S S       
Sbjct: 171 GSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSR----- 225

Query: 259 ENYLTAGLTVGQVRPLVPLQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAH 318
                 GL   +   + P + +           QSS H +R +  A P   ++   R   
Sbjct: 226 ----AGGLDWPEATEVSPSRTIRAPAVRTLQRFQSS-HRSRGVGGAVPGAVLEPVARAPS 280

Query: 319 LTVGQAAAGGSGNLLTER------STFTDSQLGNADMEMTLERAVSMLEADHMLPSRISA 372
           +     +   SG+L          S  T  +L +   ++ L  AV  L A    P+    
Sbjct: 281 VRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASD--PNLQVL 338

Query: 373 AATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLE 432
            A +IQH+C+  + A+K+   L+ + +L++L    N++VQR   GA+RNL++++ DNKL 
Sbjct: 339 GAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLA 398

Query: 433 VAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRIT 492
           + E NG+  LL+ L++  D E +K +T                                 
Sbjct: 399 LVEENGIFELLRTLREQDD-ELRKNVT--------------------------------- 424

Query: 493 RSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDF 552
                      G+LWNLSS+D LK+ +  + L  LT+ ++ P SG       + N   + 
Sbjct: 425 -----------GILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNAS-EA 472

Query: 553 DIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILH 612
           +IFYN TG LRN+SSA    R+ MR C GL+D+LV  +   +   + +DK+ EN VC+L 
Sbjct: 473 EIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLR 532

Query: 613 NLSYQLEAELPEKYSQNIYIQNRN--IQTDNNKSIGCFGSRSRKVKE---QYQDVPMPEE 667
           NLSY+L  E+P    Q +  + R         + +GCF  +SR+++E       +   E 
Sbjct: 533 NLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEV 592

Query: 668 KSNPKGVEWLWHSIVIRMYLSLIAK-SVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQ 726
             +PKG+EWLW   ++ +Y  L+ +  +  +T EA+ GALQN+TAG       +++  ++
Sbjct: 593 SKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALE 652

Query: 727 KESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTD 786
           +E  L      +   D    ++   L+RNLSRN   ++E++ + +  L+  +P +V    
Sbjct: 653 QERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKS 712

Query: 787 LLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAI-SAGDAYASNKASKAASVLLY 845
              E   +    LNN++  S   ARDLL   G++K++ I    D+  S K+S+AAS LL 
Sbjct: 713 PPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLA 772

Query: 846 SLWAHTELHHAYKKAQFKKTDFV 868
           +LW + +LH  ++   ++K DF+
Sbjct: 773 NLWQYNKLHRDFRAKGYRKEDFL 795


>gi|4502247 armadillo repeat protein [Homo sapiens]
          Length = 962

 Score =  243 bits (621), Expect = 4e-64
 Identities = 178/582 (30%), Positives = 278/582 (47%), Gaps = 77/582 (13%)

Query: 321 VGQAAAGGSGNL--LTERSTFTDSQLGNADM-EMTLERAVSMLEADHMLPSRISAAATFI 377
           + Q   G  G+L  L  RS   DS        +  L   ++ML   H +    + AA ++
Sbjct: 325 LAQPERGSMGSLDRLVRRSPSVDSARKEPRWRDPELPEVLAMLR--HPVDPVKANAAAYL 382

Query: 378 QHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDNKLEVAEL 436
           QH CF+    ++RV QLRG+  L+ LL     +V+R  CGALRNL +  D DNK  + + 
Sbjct: 383 QHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTDNKAAIRDC 442

Query: 437 NGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGV 496
            GVP L+++L+  RD E ++ +T                                     
Sbjct: 443 GGVPALVRLLRAARDNEVRELVT------------------------------------- 465

Query: 497 RDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPE--GDYPKANGLLDFDI 554
                  G LWNLSS + LK ++I   L TLT  +I+P SGW     +  K        +
Sbjct: 466 -------GTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTV 518

Query: 555 FYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNL 614
           F N +GCLRN+SS GA+ R+ +R C+GL+D+L+H ++  +     D+K+ ENCVCI+ NL
Sbjct: 519 FKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNL 578

Query: 615 SYQLEAELP--EKYSQ---NIYIQNRNIQTDNNKSIGCFGSRSRK------------VKE 657
           SY +  E+P  ++Y +            Q        CFG +  K            +  
Sbjct: 579 SYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDR 638

Query: 658 QYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMP 717
            +  + +P+     KG E L+   V+R+YLSL+ +S    T EA+ GALQNL+AG+    
Sbjct: 639 NFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWA 698

Query: 718 TSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSI 777
           T +  T V+KE GL    ++L      V +     LRNLS +   ++ I    + +LV  
Sbjct: 699 TYIRAT-VRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRN 757

Query: 778 IPDTV----PSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYAS 833
           + +      P   L  +T  +   T++ I+ +S  NAR LL   G+  ++A+ A     S
Sbjct: 758 VRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVASS--QS 815

Query: 834 NKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFVN-SRTAK 874
            + +KAAS +L ++W++ EL    +K  + K  F + + TAK
Sbjct: 816 VREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAK 857


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 372

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 373 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 417

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 418 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 477

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 478 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 533

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 534 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 593

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 594 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 652

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 653 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 711

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 712 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 760



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 562 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 620

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 621 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 652


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 372

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 373 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 417

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 418 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 477

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 478 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 533

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 534 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 593

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 594 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 652

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 653 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 711

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 712 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 760



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 562 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 620

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 621 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 652


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 372

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 373 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 417

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 418 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 477

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 478 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 533

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 534 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 593

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 594 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 652

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 653 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 711

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 712 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 760



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 562 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 620

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 621 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 652


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 372

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 373 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 417

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 418 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 477

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 478 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 533

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 534 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 593

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 594 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 652

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 653 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 711

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 712 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 760



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 562 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 620

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 621 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 652


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 372

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 373 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 417

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 418 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 477

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 478 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 533

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 534 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 593

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 594 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 652

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 653 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 711

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 712 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 760



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 562 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 620

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 621 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 652


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 473

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 474 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 518

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 519 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 578

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 579 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 634

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 635 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 694

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 695 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 753

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 754 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 812

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 813 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 861



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 663 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 721

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 722 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 753


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 473

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 474 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 518

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 519 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 578

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 579 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 634

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 635 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 694

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 695 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 753

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 754 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 812

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 813 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 861



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 663 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 721

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 722 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 753


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 473

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 474 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 518

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 519 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 578

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 579 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 634

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 635 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 694

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 695 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 753

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 754 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 812

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 813 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 861



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 663 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 721

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 722 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 753


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 473

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 474 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 518

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 519 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 578

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 579 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 634

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 635 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 694

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 695 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 753

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 754 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 812

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 813 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 861



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 663 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 721

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 722 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 753


>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
          Length = 962

 Score =  242 bits (617), Expect = 1e-63
 Identities = 165/529 (31%), Positives = 265/529 (50%), Gaps = 69/529 (13%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 473

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 474 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 518

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 519 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 578

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRKVKEQYQD-- 661
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K K+  +D  
Sbjct: 579 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKGKKPIEDPA 634

Query: 662 ---VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPT 718
              V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG      
Sbjct: 635 NDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGR 694

Query: 719 SVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSII 778
            + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P+LV  +
Sbjct: 695 YI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNL 753

Query: 779 P--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKA 836
           P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+      S K 
Sbjct: 754 PGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKE 812

Query: 837 SKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
            +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 813 VRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 861



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 663 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 721

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 722 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 753


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score =  235 bits (600), Expect = 1e-61
 Identities = 165/535 (30%), Positives = 265/535 (49%), Gaps = 75/535 (14%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 372

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 373 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 417

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 418 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 477

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRK------VKE 657
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K       K+
Sbjct: 478 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKDEWFSRGKK 533

Query: 658 QYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAG 712
             +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG
Sbjct: 534 PIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAG 593

Query: 713 SGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLP 772
                  + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P
Sbjct: 594 RWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIP 652

Query: 773 DLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDA 830
           +LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+    
Sbjct: 653 NLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SG 711

Query: 831 YASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
             S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 712 NRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 766



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 568 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 626

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 627 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 658


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score =  235 bits (600), Expect = 1e-61
 Identities = 165/535 (30%), Positives = 265/535 (49%), Gaps = 75/535 (14%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 283 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 342

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 343 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 372

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 373 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 417

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 418 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 477

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRK------VKE 657
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K       K+
Sbjct: 478 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKDEWFSRGKK 533

Query: 658 QYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAG 712
             +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG
Sbjct: 534 PIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAG 593

Query: 713 SGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLP 772
                  + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P
Sbjct: 594 RWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIP 652

Query: 773 DLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDA 830
           +LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+    
Sbjct: 653 NLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SG 711

Query: 831 YASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
             S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 712 NRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 766



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 568 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 626

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 627 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 658


>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
          Length = 968

 Score =  235 bits (600), Expect = 1e-61
 Identities = 165/535 (30%), Positives = 265/535 (49%), Gaps = 75/535 (14%)

Query: 371 SAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVF-EDNDN 429
           S AA ++QH C++  + +  V +L+GI  L+ LL    ++V    CGAL+N+ F  D DN
Sbjct: 384 SNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDN 443

Query: 430 KLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGG 489
           K+ +   +GVP L+++L++ RD++  + IT                              
Sbjct: 444 KIAIKNCDGVPALVRLLRKARDMDLTEVIT------------------------------ 473

Query: 490 RITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGW---PEGDYPKA 546
                         G LWNLSS+D +K  ++  AL  LT+ +IIP SGW   P  D  K 
Sbjct: 474 --------------GTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDC-KP 518

Query: 547 NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATEN 606
             +    +  N  GCLRN+SS  ++ R+ +R CDGL+D+L+  V+  I     D K  EN
Sbjct: 519 RHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVEN 578

Query: 607 CVCILHNLSYQLEAELP--EKYSQNIYIQNRNIQTDNN-KSIGCFGSRSRK------VKE 657
           CVC+L NLSYQ+  E+P  E+Y +       N+  +    +  CFG++  K       K+
Sbjct: 579 CVCLLRNLSYQVHREIPQAERYQE----AAPNVANNTGPHAASCFGAKKGKDEWFSRGKK 634

Query: 658 QYQD-----VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAG 712
             +D     V  P+  S  +G E L+   V+R+Y+SL+ +S      EAS GA+QNL AG
Sbjct: 635 PIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAG 694

Query: 713 SGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLP 772
                  + ++ +++E  L     +L      V K A   LRNL+ +   +  I K  +P
Sbjct: 695 RWTYGRYI-RSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIP 753

Query: 773 DLVSIIP--DTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDA 830
           +LV  +P      S +   +T  S   T+N +I  + + A+ L  T GI+K++ I+    
Sbjct: 754 NLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SG 812

Query: 831 YASNKASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV----NSRTAKAYHSLKD 881
             S K  +AA+++L ++W + EL    +K  +KK+DF     N+  +++ HS  D
Sbjct: 813 NRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDD 867



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 357 VSMLEADHMLPSRISAAATFIQHECFQK----SEARKRVNQLRGILKLLQLLKVQNEDVQ 412
           +S+L+ +   P+ + A+A  IQ+ C  +       R  + Q + +  +  LL  ++E V 
Sbjct: 669 ISLLK-ESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVV 727

Query: 413 RAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL 446
           +A  GALRNL   D  NK E+   + +P L++ L
Sbjct: 728 KAASGALRNLAV-DARNK-ELIGKHAIPNLVKNL 759


>gi|116256455 zinc finger protein 429 [Homo sapiens]
          Length = 674

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 24/28 (85%), Positives = 26/28 (92%)

Query: 473 GAVAHACNPSTLGGQGGRITRSGVRDQP 500
           G VAHACNPSTLGG+GGRITRSG RD+P
Sbjct: 646 GVVAHACNPSTLGGRGGRITRSGDRDRP 673


>gi|224451040 Yip1 interacting factor homolog B isoform 7 [Homo
           sapiens]
          Length = 291

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 23/24 (95%), Positives = 24/24 (100%)

Query: 472 PGAVAHACNPSTLGGQGGRITRSG 495
           PGAVAHACNPSTLGG+GGRITRSG
Sbjct: 265 PGAVAHACNPSTLGGRGGRITRSG 288


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 24/28 (85%), Positives = 25/28 (89%)

Query: 473 GAVAHACNPSTLGGQGGRITRSGVRDQP 500
           GAVAHACNPSTLGG+GG ITRSG RD P
Sbjct: 346 GAVAHACNPSTLGGRGGWITRSGDRDHP 373


>gi|144953913 zinc finger protein 714 [Homo sapiens]
          Length = 555

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 26/52 (50%), Positives = 31/52 (59%)

Query: 453 ETKKQITDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHG 504
           E  K     +   + R    G VAHACNP+TL G G +I RSGV+DQP QHG
Sbjct: 485 ECGKAFNQSSTLTKHRKIQQGMVAHACNPNTLRGLGEQIARSGVQDQPGQHG 536


>gi|148277022 selenoprotein P isoform 2 [Homo sapiens]
          Length = 411

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 19/21 (90%), Positives = 20/21 (95%)

Query: 474 AVAHACNPSTLGGQGGRITRS 494
           AVAHACNPSTLGGQG RITR+
Sbjct: 7   AVAHACNPSTLGGQGRRITRT 27


>gi|59859882 baculoviral IAP repeat-containing protein 5 isoform 3
           [Homo sapiens]
          Length = 165

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/22 (81%), Positives = 20/22 (90%)

Query: 472 PGAVAHACNPSTLGGQGGRITR 493
           PG VA+ACN STLGG+GGRITR
Sbjct: 76  PGTVAYACNTSTLGGRGGRITR 97


>gi|4759046 RNA polymerase I subunit isoform 2 [Homo sapiens]
          Length = 342

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 20/27 (74%), Positives = 20/27 (74%)

Query: 474 AVAHACNPSTLGGQGGRITRSGVRDQP 500
           AVAH CNPSTLGGQG  IT S  RD P
Sbjct: 315 AVAHTCNPSTLGGQGEWITGSRERDHP 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,183,534
Number of Sequences: 37866
Number of extensions: 1408423
Number of successful extensions: 4207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3965
Number of HSP's gapped (non-prelim): 136
length of query: 881
length of database: 18,247,518
effective HSP length: 111
effective length of query: 770
effective length of database: 14,044,392
effective search space: 10814181840
effective search space used: 10814181840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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