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Search of human proteins with 148612809
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148612809 WNK lysine deficient protein kinase 1 [Homo
sapiens]
(2382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 4655 0.0
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 853 0.0
gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Hom... 649 0.0
gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Hom... 649 0.0
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 619 e-176
gi|7019333 nuclear receptor binding protein [Homo sapiens] 144 8e-34
gi|91982772 mucin 17 [Homo sapiens] 138 7e-32
gi|148839316 NIMA-related kinase 4 [Homo sapiens] 127 2e-28
gi|189491759 p21-activated kinase 3 isoform d [Homo sapiens] 124 1e-27
gi|189491757 p21-activated kinase 3 isoform c [Homo sapiens] 124 1e-27
gi|189491755 p21-activated kinase 3 isoform b [Homo sapiens] 124 1e-27
gi|189491753 p21-activated kinase 3 isoform a [Homo sapiens] 124 1e-27
gi|189491751 p21-activated kinase 3 isoform a [Homo sapiens] 124 1e-27
gi|4505601 p21-activated kinase 3 isoform a [Homo sapiens] 124 1e-27
gi|83367077 mucin 16 [Homo sapiens] 122 5e-27
gi|32483399 p21-activated kinase 2 [Homo sapiens] 120 2e-26
gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens] 118 8e-26
gi|42794767 mitogen-activated protein kinase kinase kinase 3 iso... 115 7e-25
gi|42794765 mitogen-activated protein kinase kinase kinase 3 iso... 115 7e-25
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 113 2e-24
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 113 3e-24
gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens] 112 3e-24
gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo sa... 112 6e-24
gi|63998898 Yeast Sps1/Ste20-related kinase 4 isoform 2 [Homo sa... 112 6e-24
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 109 3e-23
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 109 3e-23
gi|217330634 serine/threonine kinase 36 [Homo sapiens] 109 3e-23
gi|33188459 B-Raf [Homo sapiens] 109 4e-23
gi|116284392 mucin 2 precursor [Homo sapiens] 108 5e-23
gi|85838511 mitogen-activated protein kinase kinase kinase 2 [Ho... 108 6e-23
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 4655 bits (12073), Expect = 0.0
Identities = 2382/2382 (100%), Positives = 2382/2382 (100%)
Query: 1 MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHT 60
MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHT
Sbjct: 1 MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHT 60
Query: 61 MDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPH 120
MDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPH
Sbjct: 61 MDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPH 120
Query: 121 REETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP 180
REETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP
Sbjct: 121 REETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP 180
Query: 181 ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLD 240
ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLD
Sbjct: 181 ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLD 240
Query: 241 TETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLV 300
TETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLV
Sbjct: 241 TETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLV 300
Query: 301 TELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP 360
TELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP
Sbjct: 301 TELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP 360
Query: 361 TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEY 420
TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEY
Sbjct: 361 TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEY 420
Query: 421 PYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQ 480
PYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQ
Sbjct: 421 PYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQ 480
Query: 481 EETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM 540
EETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM
Sbjct: 481 EETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM 540
Query: 541 VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQ 600
VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQ
Sbjct: 541 VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQ 600
Query: 601 TGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQG 660
TGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQG
Sbjct: 601 TGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQG 660
Query: 661 SSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQG 720
SSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQG
Sbjct: 661 SSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQG 720
Query: 721 QPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAP 780
QPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAP
Sbjct: 721 QPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAP 780
Query: 781 QVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYP 840
QVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYP
Sbjct: 781 QVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYP 840
Query: 841 VSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLL 900
VSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLL
Sbjct: 841 VSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLL 900
Query: 901 QPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNI 960
QPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNI
Sbjct: 901 QPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNI 960
Query: 961 APSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPG 1020
APSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPG
Sbjct: 961 APSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPG 1020
Query: 1021 GSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMS 1080
GSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMS
Sbjct: 1021 GSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMS 1080
Query: 1081 DGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETH 1140
DGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETH
Sbjct: 1081 DGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETH 1140
Query: 1141 NRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEP 1200
NRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEP
Sbjct: 1141 NRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEP 1200
Query: 1201 EGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIV 1260
EGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIV
Sbjct: 1201 EGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIV 1260
Query: 1261 SPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPN 1320
SPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPN
Sbjct: 1261 SPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPN 1320
Query: 1321 TAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTE 1380
TAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTE
Sbjct: 1321 TAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTE 1380
Query: 1381 EGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEI 1440
EGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEI
Sbjct: 1381 EGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEI 1440
Query: 1441 VVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPS 1500
VVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPS
Sbjct: 1441 VVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPS 1500
Query: 1501 TASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSY 1560
TASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSY
Sbjct: 1501 TASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSY 1560
Query: 1561 ISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHS 1620
ISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHS
Sbjct: 1561 ISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHS 1620
Query: 1621 QPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLET 1680
QPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLET
Sbjct: 1621 QPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLET 1680
Query: 1681 SLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVST 1740
SLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVST
Sbjct: 1681 SLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVST 1740
Query: 1741 TTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQL 1800
TTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQL
Sbjct: 1741 TTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQL 1800
Query: 1801 RRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRF 1860
RRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRF
Sbjct: 1801 RRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRF 1860
Query: 1861 QVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSD 1920
QVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSD
Sbjct: 1861 QVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSD 1920
Query: 1921 VPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPP 1980
VPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPP
Sbjct: 1921 VPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPP 1980
Query: 1981 FMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKS 2040
FMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKS
Sbjct: 1981 FMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKS 2040
Query: 2041 LPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIES 2100
LPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIES
Sbjct: 2041 LPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIES 2100
Query: 2101 LYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASV 2160
LYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASV
Sbjct: 2101 LYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASV 2160
Query: 2161 LHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTN 2220
LHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTN
Sbjct: 2161 LHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTN 2220
Query: 2221 TVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPG 2280
TVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPG
Sbjct: 2221 TVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPG 2280
Query: 2281 MARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGT 2340
MARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGT
Sbjct: 2281 MARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGT 2340
Query: 2341 GGPAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT 2382
GGPAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT
Sbjct: 2341 GGPAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT 2382
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 853 bits (2205), Expect = 0.0
Identities = 638/1644 (38%), Positives = 814/1644 (49%), Gaps = 271/1644 (16%)
Query: 78 RFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQV---- 133
RF RRSV+ + E PGL A P PP+P + + T ++
Sbjct: 40 RFLRRSVV---ESDQEEPPGLEA--------AEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
Query: 134 -----AQQPPAA-----AAPGEQAVAGPAP---------------STVPSSTSKDRPVSQ 168
A PAA APG A AGP P T P+ R +
Sbjct: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
Query: 169 PSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIG 228
++ E A+ G EP+EE +DD ++L KAV S DGRFLKFDIE+G
Sbjct: 149 ATVRKEDEGAAEAKPEPGRTRRDEPEEE----EDDEDDL--KAVATSLDGRFLKFDIELG 202
Query: 229 RGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWE 288
RGSFKTVYKGLDTET VEVAWCELQDRKLTK ERQRFKEEAEMLKGLQHPNIVRFYD WE
Sbjct: 203 RGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWE 262
Query: 289 STVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHR 348
S+ KGK+CIVLVTELMTSGTLKTYLKRFKVMK KVLRSWCRQILKGL FLHTRTPPIIHR
Sbjct: 263 SSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHR 322
Query: 349 DLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAF 408
DLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEE YDESVDVYAF
Sbjct: 323 DLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAF 382
Query: 409 GMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERY 468
GMCMLEMATSEYPYSECQNAAQIYR+VT G+KPASF+KV PE+KEII CI +NK+ERY
Sbjct: 383 GMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERY 442
Query: 469 SIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDL 528
IKDLL+HAFF E+TGVRVELAEED G K I L L +ED KKLKGK KDN AIEF+FDL
Sbjct: 443 EIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDL 502
Query: 529 ERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESS 588
E++ P++VAQEM+ESG+ E D K +AK+I+DRV+LI+ +RE+ + Q K++Q+ S
Sbjct: 503 EKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRER--IWPALQPKEQQDVGS 560
Query: 589 LKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQV------EPEEPEADQHQQLQY 642
P + G P + Q EPEEPEADQH
Sbjct: 561 ------------------PDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPT 602
Query: 643 QQPSI-SVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTG------------T 689
S S+ SD T DSGQGS+V+++S+ SSQQ+V GS + A S
Sbjct: 603 LPTSATSLASDSTFDSGQGSTVYSDSQ-SSQQSVMLGSLADAAPSPAQCVCSPPVSEGPV 661
Query: 690 VPGHIPSTVQAQSQPHG-------------------------------VYPPSSVAQGQS 718
+P +PS + A QP V PP S
Sbjct: 662 LPQSLPS-LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 720
Query: 719 QGQPSSSSLTGVSSSQPIQHPQ--QQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQ 776
GQP+ +QP PQ Q + P + L+ S +P+
Sbjct: 721 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 780
Query: 777 PQAP-----QVLPQVSAGKQLPVSQPVPTIQGEP----QIPVATQPSVVPVH--SGAHFL 825
PQAP QV PQ+ +P P+ I G P +P AT P V P S A L
Sbjct: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
Query: 826 P-VGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASS----- 879
P + PLP P P P+ + + PH A I A T PLL +A
Sbjct: 841 PSLAAPLP-PASPALPLQAVKL--PHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAAL 897
Query: 880 ---ATTAAIPG---VSTVVPSQLPT--------------------------------LLQ 901
+ A +PG P PT +L
Sbjct: 898 SIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLP 957
Query: 902 PVTQLPSQ--VHPQLLQPAVQSMGIPANLG-QAAEVPLSSGDVLYQGFPPRLPPQ----- 953
P LP Q + PQ +P + L Q P + V + P LP Q
Sbjct: 958 PQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAA 1017
Query: 954 ---------YPGDSNIAPSSNVASVCIH-STVLSPPMPTEVLATPGYFPTVVQPYVESNL 1003
+P + ++ V +V + + VLSPP+P +L P ++ + S
Sbjct: 1018 TPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAA---PELLPQFPSS-- 1072
Query: 1004 LVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPA-----EPVAVAQTQA 1058
+ V VQ S P + P + L G++ P EPV Q
Sbjct: 1073 ---LATVSASVQ-SVPTQTATLLPPANPP---LPGGPGIASPCPTVQLTVEPVQEEQASQ 1125
Query: 1059 TQPTTLASSVDS-AHSDVASG--MSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKT 1115
+P L S +S SDV SG +SD E GR EGR ++H+R+S R+RSR E+
Sbjct: 1126 DKPPGLPQSCESYGGSDVTSGKELSDSCEGA-FGGGRLEGRAARKHHRRSTRARSRQERA 1184
Query: 1116 SRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERE 1175
SRP+L ILNV N GD++VECQLETHN KMVTFKFDLDGD P+EIAT MV +DFIL ERE
Sbjct: 1185 SRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERE 1244
Query: 1176 SFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASS 1235
+F++Q++++++KA++MLSED + D G +G + + + P+ +
Sbjct: 1245 TFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQN 1304
Query: 1236 MPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLS 1295
V+H+ R FI+ PV E E+ P +S + +
Sbjct: 1305 --------------VLHTGKRWFIICPVAEHPAPEA---PESSPPLPLSSLPPEASQDSA 1347
Query: 1296 HSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAP 1355
LS ++ S L Q+ + P + P P PP + +P AA
Sbjct: 1348 PYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPP----VTALPQDGAA--- 1400
Query: 1356 VPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVT--SGGLPIPPVSESPVLSSVV 1413
PATS+ P S + Q+ G T G+ + P+ E+P+
Sbjct: 1401 -PATSTMPEPASGTASQA----------GGPGTPQGLTSELETSQPLAETHEAPLAVQ-- 1447
Query: 1414 SSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPA 1473
P VV ++ +P+ + ++ P+ S S + + P P PA
Sbjct: 1448 -----PLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPA 1502
Query: 1474 VVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTS 1533
V + ++ + + + PS S P V + SLD+
Sbjct: 1503 AVGAVSLATSQLPSPPLGPTVPPQPPSALE------SDGEGPPPRVGFVDSTIKSLDEKL 1556
Query: 1534 HSSTTGLAFSLSAPSSSSSPGAGV 1557
+ L + P+SS+S G V
Sbjct: 1557 RT----LLYQEHVPTSSASAGTPV 1576
Score = 145 bits (365), Expect = 6e-34
Identities = 250/988 (25%), Positives = 371/988 (37%), Gaps = 225/988 (22%)
Query: 1400 IPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS 1459
I PV+E P + SS +P +S+ P ++ + +SS PS S S
Sbjct: 1315 ICPVAEHPAPEAPESSPPLP----LSSLPPEASQDSAPYKDQLSSKE-QPSFLASQQLLS 1369
Query: 1460 AGGSTATPG-------PKPPAVVSQQAAGSTTVGATLTSVSTTTSF----PSTASQLSIQ 1508
G + PG P P V + G+ +T+ ++ T+ P T L+ +
Sbjct: 1370 QAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSE 1429
Query: 1509 LSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLH 1568
L TS P LAET H GLA AP ++S+ A
Sbjct: 1430 LE--TSQP-LAET-----HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPR--------- 1472
Query: 1569 PLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAV--QQTLIHSQ-PQPA 1625
P+ P A P+ PQ P L QP +PA +L SQ P P
Sbjct: 1473 ----------EPLPPPAPEPSPHSGTPQ----PALGQPAPLLPAAVGAVSLATSQLPSPP 1518
Query: 1626 LLPNQPHTHCPEVDSDTQPKAPGI----DDIKTLEEKLRSL-FSEHSSSGAQHASVSLET 1680
L P P ++SD + P + IK+L+EKLR+L + EH
Sbjct: 1519 LGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEH-------------- 1564
Query: 1681 SLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPV-VTPGQVSTPVS 1739
V S+ + G P V P + + G +ALP P G+V P
Sbjct: 1565 --VPTSSASAGTPVE-VGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLP-- 1619
Query: 1740 TTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDL--D 1797
+P S+ T+ V+ GT S+T P L D
Sbjct: 1620 ------QPLVEKSELAPTRGAVMEQGTS----------------SSMTAESSPRSMLGYD 1657
Query: 1798 AQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQP------QKGVSQVKEGPV-LATSS 1850
R+ S + V V P + A +P + G S + P + T
Sbjct: 1658 RDGRQVASDSHV-----VPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVG 1712
Query: 1851 GAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPN 1910
G ++ + + E ++ S AK+V S S + +SP S P+
Sbjct: 1713 GQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPD 1772
Query: 1911 GITIPGISS-DVPESAHKT-TASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKIT 1968
SS DV + + TAS + G+P +
Sbjct: 1773 VYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVS-------------------------S 1807
Query: 1969 DTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSG 2028
D+ EGP A PP +QA LP + G AFL R GS
Sbjct: 1808 DSGDEGPRARPPVQ--KQASLPV------------SGSVAGDFVKKATAFLQRPSRAGSL 1853
Query: 2029 SPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQ 2088
P +P ++ K +P+ +++ S S SY+SSDN+S++ED D+K EL+ LR+KHLKEI
Sbjct: 1854 GPETPSRVGMK-VPTISVTSFHSQS---SYISSDNDSELEDADIKKELQSLREKHLKEIS 1909
Query: 2089 DLQSRQKHEIESLYTKLGK-VPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQ 2147
+LQS+QK EIE+LY +LGK +PP V AP +GRRR+ +KSK + L +
Sbjct: 1910 ELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKV 1969
Query: 2148 L---SGNLSGQS-AASVLHPQQ-----TLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAF 2198
+ +G+L+ S P Q T G ++ Q Q ++ S SSD + S
Sbjct: 1970 VASSTGHLADSSRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSD-ICSGL 2028
Query: 2199 TSDGA----------------ISVPSLSAP----------------------GQGTSSTN 2220
SDG ++ S S P G+ SS +
Sbjct: 2029 ASDGGGARGQGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRS 2088
Query: 2221 TVGATVNSQAAQAQPPA-------MTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGS--- 2270
+ + QP ++++KGTFTDDLHKLVD W + + + +
Sbjct: 2089 STSSLAPGPEPGPQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQ 2148
Query: 2271 ----------KGHMNYEGPGMARKFSAP 2288
+ + PG AR +AP
Sbjct: 2149 LKQTQKLQDMEAQAGWAAPGEARAMTAP 2176
Score = 63.2 bits (152), Expect = 3e-09
Identities = 210/980 (21%), Positives = 325/980 (33%), Gaps = 185/980 (18%)
Query: 1145 VTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQ 1204
+ F FDL+ + P+E+A M+ + F + + +R+ + ++ ++
Sbjct: 496 IEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRV----------ALIQWRRER 545
Query: 1205 GLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVP 1264
+LQ K+ K G P+P QV + A P P
Sbjct: 546 IWPALQPKEQQDVGSPDKARG---PPVPLQ-------------VQVTYHAQAGQPGPPEP 589
Query: 1265 ESRLRESKVFPSEI---TDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNT 1321
E + + P + ++A+ + G + + S S QQ S + + P+
Sbjct: 590 EEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQ--SVMLGSLADAAPSP 647
Query: 1322 APPNFSHTGPTFPVVPPFLSSIAGVPTTAAA----TAPVPATSSPPNDISTSVIQSEVTV 1377
A S PV+P L S+ AA VPA + PP+ +Q
Sbjct: 648 AQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPS------LQQHFPD 701
Query: 1378 PTEEGIAGV--ATSTGVVTSGGLPIPPVSESPVLS--SVVSSITIP-AVVSISTTSPSLQ 1432
P A V ST + T G P PP + P L+ + + + P VV + P L
Sbjct: 702 PA-MSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760
Query: 1433 VPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSV 1492
+ + V + L P A P P AG + L +
Sbjct: 761 PYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDL 820
Query: 1493 STTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSS 1552
T T P Q S + P+LA + ++ +L + L+ P +
Sbjct: 821 PTATVPPVPPPQ---YFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIV 877
Query: 1553 PG--AGVSSYISQPGGLHPLVIPSVIASTP-------ILPQAAGPTSTP----------- 1592
P A + P G+ L I S +A P PQ A PT P
Sbjct: 878 PNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMA-PTDVPPSPHHTVQNMR 936
Query: 1593 LLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSD----TQPKAPG 1648
P P++PP QP V PQP L P P + QP P
Sbjct: 937 ATPPQPALPP--QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPP 994
Query: 1649 IDDIKTLEEKLRSLFSEHSSSGAQHAS-VSLETSLVIESTVTPGIPTTAVAPSKLLTSTT 1707
+ E L+ E ++ A S + L V +PT V P+ +L+
Sbjct: 995 QPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSP-- 1052
Query: 1708 STCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTE 1767
PL V LP P + P Q + ++T ++ V+ P A +LP
Sbjct: 1053 ---------PLPEVLLPAAPELLP-QFPSSLATVSASVQ------SVPTQTATLLP---- 1092
Query: 1768 LPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAIT 1827
PA PP PG S P TV V PV
Sbjct: 1093 -PAN-------PPLPGGPGIASPCP-----------------TVQLTVEPVQE------E 1121
Query: 1828 EAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFES 1887
+A G+ Q E S G G+ ++S + +GA G+ + A+ H S
Sbjct: 1122 QASQDKPPGLPQSCE------SYGGSDVTSGK-ELSDSCEGAFGGGRLEGRAARKHHRRS 1174
Query: 1888 STSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQ 1947
+ + S +S P T++ G + + + HK + D P ++ +
Sbjct: 1175 TRARSRQERASRPRLTILNVCNTGDKM--VECQLETHNHKMVTFKFDLDGDAPDEIATYM 1232
Query: 1948 V---------TTTANKVGRFSVSKTEDKITD----TKKEGPVASPPFMDL---------- 1984
V T + + + K ED +++ + P SPP +
Sbjct: 1233 VEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESR 1292
Query: 1985 -EQAVLP-------------------AVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVD 2024
QA P A P E PE S P L+ S PEA+ S
Sbjct: 1293 QSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLS--SLPPEASQDSAPYK 1350
Query: 2025 DGSGSPHSPHQLSSKSLPSQ 2044
D S P L+S+ L SQ
Sbjct: 1351 DQLSSKEQPSFLASQQLLSQ 1370
Score = 32.3 bits (72), Expect = 5.7
Identities = 83/361 (22%), Positives = 111/361 (30%), Gaps = 73/361 (20%)
Query: 1330 GPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATS 1389
GPT P PP G S + T + Q V PT AG
Sbjct: 1520 GPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV--PTSSASAGTPVE 1577
Query: 1390 TG----------------VVTSGGLPIPPVSES----------PVLSSVVSSITIPAVVS 1423
G V G L +PPV + P++ + T AV+
Sbjct: 1578 VGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVME 1637
Query: 1424 ISTTSPSLQVPTSTSEI--------VVSSTALYPSVTVSATS--------------ASAG 1461
T+S + S + V S + + PSV + AG
Sbjct: 1638 QGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAG 1697
Query: 1462 GSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAET 1521
S+A P P V QA+ T+GA S + + + T E
Sbjct: 1698 ESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEW 1757
Query: 1522 VVVSAHS----------LDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLV 1571
+ S HS LD+ S LA + +SS G G S G P
Sbjct: 1758 TLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVG-EPVSSDSGDEGPRA 1816
Query: 1572 IPSV--IASTPILPQAAG---PTSTPLLPQVPSIPPLVQPVA------NVPAVQQTLIHS 1620
P V AS P+ AG +T L Q PS + P VP + T HS
Sbjct: 1817 RPPVQKQASLPVSGSVAGDFVKKATAFL-QRPSRAGSLGPETPSRVGMKVPTISVTSFHS 1875
Query: 1621 Q 1621
Q
Sbjct: 1876 Q 1876
Score = 32.0 bits (71), Expect = 7.5
Identities = 38/147 (25%), Positives = 55/147 (37%), Gaps = 29/147 (19%)
Query: 82 RSVICDSNATALELPGLP-------LSLPQPSIPA---AVPQSAPPEPHREETVTATAT- 130
RS +C + L LP +P + LPQP + A + A E ++TA ++
Sbjct: 1594 RSEVCGGD---LALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSP 1650
Query: 131 -SQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVG----SKEEPPPARSGS 185
S + + V P VP+ R G S EPPP+ G+
Sbjct: 1651 RSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGT 1710
Query: 186 GGGSAKEPQ----------EERSQQQD 202
GG A PQ +R +QQD
Sbjct: 1711 VGGQASHPQTLGARALGSPRKRPEQQD 1737
>gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Homo
sapiens]
Length = 1800
Score = 649 bits (1674), Expect = 0.0
Identities = 386/687 (56%), Positives = 455/687 (66%), Gaps = 54/687 (7%)
Query: 147 AVAGPAPSTVPSSTSKDRPVSQPSLV--GSKEEPPPARSGSGGGSAKEPQEERSQQQDDI 204
A + P + ++ + R PS V G +E S S +K+ +E+++++ +
Sbjct: 72 AESSPKDERIKAAMNIPRVDKLPSNVLRGGQEVKYEQCSKSTSEISKDCFKEKNEKEME- 130
Query: 205 EELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQR 264
EE E KAV S GRFLKFDIE+GRG+FKTVYKGLDTET VEVAWCELQDRKLTK+E+QR
Sbjct: 131 EEAEMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQR 190
Query: 265 FKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVL 324
FKEEAEMLKGLQHPNIVRFYDSWES +KGKKCIVLVTELMTSGTLKTYLKRFKVMK KVL
Sbjct: 191 FKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVL 250
Query: 325 RSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVI 384
RSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL R SFAKSVI
Sbjct: 251 RSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVI 310
Query: 385 GTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASF 444
GTPEFMAPEMYEE YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYR+VTSG+KPASF
Sbjct: 311 GTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASF 370
Query: 445 DKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWL 504
+KV PEVKEIIEGCIRQNK ER SI+DLLNHAFF E+TG+RVELAEEDD ++ L L
Sbjct: 371 NKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVELAEEDDCSNSSLALRL 430
Query: 505 RIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSL 564
+ED KKLKGK+KDNEAIEFSF+LE D PE+VA EMV+SG+ E D K +AK+I+DRV+
Sbjct: 431 WVEDPKKLKGKHKDNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVAKSIRDRVTP 490
Query: 565 IKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVS 624
IK+ RE K+ L+++ + S + P +T +P A +
Sbjct: 491 IKKTRE------------KKPAGCLEERRDSQCKSMGNVFPQPQ-NTTLPLA----PAQQ 533
Query: 625 TQVEPEEPEADQH--QQLQYQQPS---ISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGS 679
T E EE E DQH QQL ++P SV D ++G S + +++ SSQ +V+Y S
Sbjct: 534 TGAECEETEVDQHVRQQLLQRKPQQHCSSVTGDNLSEAGAASVIHSDT--SSQPSVAYSS 591
Query: 680 QHEQA--------HSTGTVPGHIPSTVQA---QSQPHGVYPPSSVAQGQ----SQGQPS- 723
+ VPG I S+ Q Q G+ S + Q Q QGQ +
Sbjct: 592 NQTMGSQMVSNIPQAEVNVPGQIYSSQQLVGHYQQVSGLQKHSKLTQPQILPLVQGQSTV 651
Query: 724 --SSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTV---------QYSLSQTSTSSEATTAQ 772
L SQP P Q + Q P Q V + L ++ ATT +
Sbjct: 652 LPVHVLGPTVVSQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKPDLVRSLNQDVATTKE 711
Query: 773 PVSQPQAPQVLPQVSAGKQLPVSQPVP 799
VS P P + KQ S P P
Sbjct: 712 NVSSPDNPSGNGKQDRIKQRRASCPRP 738
Score = 126 bits (316), Expect = 3e-28
Identities = 237/994 (23%), Positives = 375/994 (37%), Gaps = 237/994 (23%)
Query: 1470 KPPAVVSQQAAGSTTVGATLTSVSTTTS----FPSTASQLSIQLS------SSTSTPTLA 1519
K PA++ Q + S S +T+ P+ L+ Q S T + A
Sbjct: 955 KQPAILYQVEDNRQIMAPVTNSSSYSTTSVRAVPAECEGLTKQASIFIPVYPCHQTASQA 1014
Query: 1520 ETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIAST 1579
+ ++ +TS +S T LAF + S A + +ISQ G + + +
Sbjct: 1015 DALMSHPGESTQTSGNSLTTLAFDQKPQTLSVQQPAMDAEFISQEG-------ETTVNTE 1067
Query: 1580 PILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVD 1639
P+ PT TP L P +QP T E D
Sbjct: 1068 ASSPKTVIPTQTPGLE-----PTTLQP--------------------------TTVLESD 1096
Query: 1640 SDTQPKAPGIDD-IKTLEEKLRSL-FSEHSSSG----AQHASVSLETSLVIESTVTPGIP 1693
+ PK D+ IKTL+EKLR+L + EHS S +Q + S+++ + T P
Sbjct: 1097 GERPPKLEFADNRIKTLDEKLRNLLYQEHSISSIYPESQKDTQSIDSPFSSSAEDTLSCP 1156
Query: 1694 TTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVST------PVSTTTSGV-- 1745
T V S P G+ L P +S +++ S +
Sbjct: 1157 VTEVIAISHCGIKDSPVQSPNFQQTGSKLLSNVAASQPANISVFKRDLNVITSVPSELCL 1216
Query: 1746 ----KPGTAPSKPPLTKAPVLPVGT-ELPAG--------TLPSEQLPPFPGPSLTQSQQP 1792
+ P P A V G L G T PS + P S +
Sbjct: 1217 HEMSSDASLPGDPEAYPAAVSSGGAIHLQTGGGYFGLSFTCPSLKNPI----SKKSWTRK 1272
Query: 1793 LEDLDAQLRRTLS---------PEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEG 1843
L+ +LR++ S E + SA+ P P +T T + +++ K
Sbjct: 1273 LKSWAYRLRQSTSFFKRSKVRQVETEEMRSAIAP----DPIPLTRESTADTRALNRCK-- 1326
Query: 1844 PVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSS-SSPES 1902
+ +G F+ GRFQV Q+ K S + + S T+ SS + + +S
Sbjct: 1327 ------AMSGSFQRGRFQVITIPQ--QQSAKMTSFGIEHISVFSETNHSSEEAFIKTAKS 1378
Query: 1903 TLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVS- 1961
LV+ EP ++ P+++ +A +T + K V + FS +
Sbjct: 1379 QLVEIEP--------ATQNPKTSFSYEKLQALQETCKENK----GVPKQGDNFLSFSAAC 1426
Query: 1962 KTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSR 2021
+T+ +KE S ++ + + KE+ L+ PSSD E S
Sbjct: 1427 ETDVSSVTPEKEFEETSATGSSMQSG---SELLLKEREILTAGKQ---PSSDSE---FSA 1477
Query: 2022 DVDDGSGSPHSPHQLSSKSLP---SQNLSQSLSNSFNS--SYMSSDNESDIEDEDLKLEL 2076
+ S S++ LP Q +Q+ S+ F S S MSSD+ES+IEDEDLK+EL
Sbjct: 1478 SLAGSGKSVAKTGPESNQCLPHHEEQAYAQTQSSLFYSPSSPMSSDDESEIEDEDLKVEL 1537
Query: 2077 RRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPA------VIIPPAAPLSGRRRRPTKS 2130
+RLR+KH++E+ +LQ++Q E++ LY +L + + + +PPA+P RRP
Sbjct: 1538 QRLREKHIQEVVNLQTQQNKELQELYERLRSIKDSKTQSTEIPLPPASP-----RRPRSF 1592
Query: 2131 KGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPS 2190
K SR PQ H I +G++ L+ L+
Sbjct: 1593 KSKLRSR-------------------------PQSLTHVDNGIVATGKSCLINELE---- 1623
Query: 2191 SDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTSSRKGTFTDDL 2250
N + N+ + Q P +S+KG FTDDL
Sbjct: 1624 -----------------------------NPLCVESNAASCQQSP----ASKKGMFTDDL 1650
Query: 2251 HKLVDNWARDAM-------NLSGRRGSKGHMNYEGPGMARKFSAPGQL-----CISMTSN 2298
HKLVD+W ++A+ +L+ + S+ + E + + P + IS S
Sbjct: 1651 HKLVDDWTKEAVGNSLIKPSLNQLKQSQHKLETENWNKVSE-NTPSTMGYTSTWISSLSQ 1709
Query: 2299 LGGSAPISAASATSLGHFTKSMCPPQQYGFP---------ATPFGAQWSGTGGPAPQPL- 2348
+ G+ P S SL F P YG P + QW G G Q +
Sbjct: 1710 IRGAVPTSLPQGLSLPSFPG---PLSSYGMPHVCQYNAVAGAGYPVQWVGISGTTQQSVV 1766
Query: 2349 ------GQFQPVGTASLQNFNISNLQKSISNPPG 2376
G FQP ++Q F S++Q + PPG
Sbjct: 1767 IPAQSGGPFQP--GMNMQAFPTSSVQNPATIPPG 1798
Score = 112 bits (279), Expect = 6e-24
Identities = 79/198 (39%), Positives = 110/198 (55%), Gaps = 12/198 (6%)
Query: 1027 PTTSSQQAVLEST-QGVSQVAP-AEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNE 1084
PT SQ V T Q V Q+ P ++PV Q A L V S + DVA+ E
Sbjct: 659 PTVVSQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKPDL---VRSLNQDVATT----KE 711
Query: 1085 NVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKM 1144
NV SS G + ++ S R EK ++ +L +L VS GD +VECQLETHN KM
Sbjct: 712 NV-SSPDNPSGNGKQDRIKQRRASCPRPEKGTKFQLTVLQVSTSGDNMVECQLETHNNKM 770
Query: 1145 VTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQ 1204
VTFKFD+DGD PE+IA MV ++F+L E+E FV+++R I+ +A E+L V E
Sbjct: 771 VTFKFDVDGDAPEDIADYMVEDNFVLESEKEKFVEELRAIVGQAQEIL--HVHFATERAT 828
Query: 1205 GLESLQGKDDYGFSGSQK 1222
G++S+ + +GS +
Sbjct: 829 GVDSITVDSNSSQTGSSE 846
Score = 40.0 bits (92), Expect = 0.027
Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 47/284 (16%)
Query: 518 DNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVRE 577
+N+ + F FD++ D PED+A MVE +V E + + K E R +V +
Sbjct: 767 NNKMVTFKFDVDGDAPEDIADYMVEDNFVLESEKE-------------KFVEELRAIVGQ 813
Query: 578 EQE-----KKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQV----- 627
QE + + + S++SQTG + ++ S SA S+ V
Sbjct: 814 AQEILHVHFATERATGVDSITVDSNSSQTGSSEQVQINSTSTQTSNESAPQSSPVGRWRF 873
Query: 628 ---------EPEEPEADQHQQ--LQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVS 676
E + P + QH + + P S + + + + + E+ + +
Sbjct: 874 CINQTIRNRETQSPPSLQHSMSAVPGRHPLPSPKNTSNKEISRDTLLTIENNPCHRALFT 933
Query: 677 YGSQHEQAHSTGTVPGHIPSTVQAQS-QPHGVYPPSSVAQGQSQGQPSSS-SLTGVSSSQ 734
S+H+ V G I ++ QP +Y Q + SSS S T V +
Sbjct: 934 SKSEHKD-----VVDGKISECASVETKQPAILYQVEDNRQIMAPVTNSSSYSTTSVRAV- 987
Query: 735 PIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQ 778
P + +G+ + A V Y QT++ ++A + P Q
Sbjct: 988 ----PAECEGLTKQASIFIPV-YPCHQTASQADALMSHPGESTQ 1026
>gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Homo
sapiens]
Length = 1743
Score = 649 bits (1674), Expect = 0.0
Identities = 386/687 (56%), Positives = 455/687 (66%), Gaps = 54/687 (7%)
Query: 147 AVAGPAPSTVPSSTSKDRPVSQPSLV--GSKEEPPPARSGSGGGSAKEPQEERSQQQDDI 204
A + P + ++ + R PS V G +E S S +K+ +E+++++ +
Sbjct: 72 AESSPKDERIKAAMNIPRVDKLPSNVLRGGQEVKYEQCSKSTSEISKDCFKEKNEKEME- 130
Query: 205 EELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQR 264
EE E KAV S GRFLKFDIE+GRG+FKTVYKGLDTET VEVAWCELQDRKLTK+E+QR
Sbjct: 131 EEAEMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQR 190
Query: 265 FKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVL 324
FKEEAEMLKGLQHPNIVRFYDSWES +KGKKCIVLVTELMTSGTLKTYLKRFKVMK KVL
Sbjct: 191 FKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVL 250
Query: 325 RSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVI 384
RSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL R SFAKSVI
Sbjct: 251 RSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVI 310
Query: 385 GTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASF 444
GTPEFMAPEMYEE YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYR+VTSG+KPASF
Sbjct: 311 GTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASF 370
Query: 445 DKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWL 504
+KV PEVKEIIEGCIRQNK ER SI+DLLNHAFF E+TG+RVELAEEDD ++ L L
Sbjct: 371 NKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVELAEEDDCSNSSLALRL 430
Query: 505 RIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSL 564
+ED KKLKGK+KDNEAIEFSF+LE D PE+VA EMV+SG+ E D K +AK+I+DRV+
Sbjct: 431 WVEDPKKLKGKHKDNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVAKSIRDRVTP 490
Query: 565 IKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVS 624
IK+ RE K+ L+++ + S + P +T +P A +
Sbjct: 491 IKKTRE------------KKPAGCLEERRDSQCKSMGNVFPQPQ-NTTLPLA----PAQQ 533
Query: 625 TQVEPEEPEADQH--QQLQYQQPS---ISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGS 679
T E EE E DQH QQL ++P SV D ++G S + +++ SSQ +V+Y S
Sbjct: 534 TGAECEETEVDQHVRQQLLQRKPQQHCSSVTGDNLSEAGAASVIHSDT--SSQPSVAYSS 591
Query: 680 QHEQA--------HSTGTVPGHIPSTVQA---QSQPHGVYPPSSVAQGQ----SQGQPS- 723
+ VPG I S+ Q Q G+ S + Q Q QGQ +
Sbjct: 592 NQTMGSQMVSNIPQAEVNVPGQIYSSQQLVGHYQQVSGLQKHSKLTQPQILPLVQGQSTV 651
Query: 724 --SSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTV---------QYSLSQTSTSSEATTAQ 772
L SQP P Q + Q P Q V + L ++ ATT +
Sbjct: 652 LPVHVLGPTVVSQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKPDLVRSLNQDVATTKE 711
Query: 773 PVSQPQAPQVLPQVSAGKQLPVSQPVP 799
VS P P + KQ S P P
Sbjct: 712 NVSSPDNPSGNGKQDRIKQRRASCPRP 738
Score = 112 bits (279), Expect = 6e-24
Identities = 79/198 (39%), Positives = 110/198 (55%), Gaps = 12/198 (6%)
Query: 1027 PTTSSQQAVLEST-QGVSQVAP-AEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNE 1084
PT SQ V T Q V Q+ P ++PV Q A L V S + DVA+ E
Sbjct: 659 PTVVSQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKPDL---VRSLNQDVATT----KE 711
Query: 1085 NVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKM 1144
NV SS G + ++ S R EK ++ +L +L VS GD +VECQLETHN KM
Sbjct: 712 NV-SSPDNPSGNGKQDRIKQRRASCPRPEKGTKFQLTVLQVSTSGDNMVECQLETHNNKM 770
Query: 1145 VTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQ 1204
VTFKFD+DGD PE+IA MV ++F+L E+E FV+++R I+ +A E+L V E
Sbjct: 771 VTFKFDVDGDAPEDIADYMVEDNFVLESEKEKFVEELRAIVGQAQEIL--HVHFATERAT 828
Query: 1205 GLESLQGKDDYGFSGSQK 1222
G++S+ + +GS +
Sbjct: 829 GVDSITVDSNSSQTGSSE 846
Score = 98.6 bits (244), Expect = 6e-20
Identities = 171/703 (24%), Positives = 277/703 (39%), Gaps = 132/703 (18%)
Query: 1470 KPPAVVSQQAAGSTTVGATLTSVSTTTS----FPSTASQLSIQLS------SSTSTPTLA 1519
K PA++ Q + S S +T+ P+ L+ Q S T + A
Sbjct: 955 KQPAILYQVEDNRQIMAPVTNSSSYSTTSVRAVPAECEGLTKQASIFIPVYPCHQTASQA 1014
Query: 1520 ETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIAST 1579
+ ++ +TS +S T LAF + S A + +ISQ G + + +
Sbjct: 1015 DALMSHPGESTQTSGNSLTTLAFDQKPQTLSVQQPAMDAEFISQEG-------ETTVNTE 1067
Query: 1580 PILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVD 1639
P+ PT TP L P +QP T E D
Sbjct: 1068 ASSPKTVIPTQTPGLE-----PTTLQP--------------------------TTVLESD 1096
Query: 1640 SDTQPKAPGIDD-IKTLEEKLRSL-FSEHSSSG----AQHASVSLETSLVIESTVTPGIP 1693
+ PK D+ IKTL+EKLR+L + EHS S +Q + S+++ + T P
Sbjct: 1097 GERPPKLEFADNRIKTLDEKLRNLLYQEHSISSIYPESQKDTQSIDSPFSSSAEDTLSCP 1156
Query: 1694 TTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSK 1753
T V + + + +PV +P T S + A S+
Sbjct: 1157 VTEV------------------IAISHCGIKDSPVQSPN-----FQQTGSKLLSNVAASQ 1193
Query: 1754 PPLTKA--PVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITV 1811
P L V T +P+ E P ++ + E +
Sbjct: 1194 PANISVFKRDLNVITSVPSELCLHEMSSDASLPGDPEAYPAAVSSGGAIHLQTGVETEEM 1253
Query: 1812 TSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQK 1871
SA+ P P +T T + +++ K + +G F+ GRFQV Q+
Sbjct: 1254 RSAIAP----DPIPLTRESTADTRALNRCK--------AMSGSFQRGRFQVITIPQ--QQ 1299
Query: 1872 EGKNKSEDAKSVHFESSTSESSVLSS-SSPESTLVKPEPNGITIPGISSDVPESAHKTTA 1930
K S + + S T+ SS + + +S LV+ EP ++ P+++
Sbjct: 1300 SAKMTSFGIEHISVFSETNHSSEEAFIKTAKSQLVEIEP--------ATQNPKTSFSYEK 1351
Query: 1931 SEAKSDTGQPTKVGRFQVTTTANKVGRFSVS-KTEDKITDTKKEGPVASPPFMDLEQAVL 1989
+A +T + K V + FS + +T+ +KE S ++
Sbjct: 1352 LQALQETCKENK----GVPKQGDNFLSFSAACETDVSSVTPEKEFEETSATGSSMQSG-- 1405
Query: 1990 PAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLP---SQNL 2046
+ + KE+ L+ PSSD E S + S S++ LP Q
Sbjct: 1406 -SELLLKEREILTAGKQ---PSSDSE---FSASLAGSGKSVAKTGPESNQCLPHHEEQAY 1458
Query: 2047 SQSLSNSFNS--SYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTK 2104
+Q+ S+ F S S MSSD+ES+IEDEDLK+EL+RLR+KH++E+ +LQ++Q E++ LY +
Sbjct: 1459 AQTQSSLFYSPSSPMSSDDESEIEDEDLKVELQRLREKHIQEVVNLQTQQNKELQELYER 1518
Query: 2105 LGKVPPA------VIIPPAAPLSGRRRRPTKSKGSKSSRSSSL 2141
L + + + +PPA+P RRP K SR SL
Sbjct: 1519 LRSIKDSKTQSTEIPLPPASP-----RRPRSFKSKLRSRPQSL 1556
Score = 40.0 bits (92), Expect = 0.027
Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 47/284 (16%)
Query: 518 DNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVRE 577
+N+ + F FD++ D PED+A MVE +V E + + K E R +V +
Sbjct: 767 NNKMVTFKFDVDGDAPEDIADYMVEDNFVLESEKE-------------KFVEELRAIVGQ 813
Query: 578 EQE-----KKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQV----- 627
QE + + + S++SQTG + ++ S SA S+ V
Sbjct: 814 AQEILHVHFATERATGVDSITVDSNSSQTGSSEQVQINSTSTQTSNESAPQSSPVGRWRF 873
Query: 628 ---------EPEEPEADQHQQ--LQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVS 676
E + P + QH + + P S + + + + + E+ + +
Sbjct: 874 CINQTIRNRETQSPPSLQHSMSAVPGRHPLPSPKNTSNKEISRDTLLTIENNPCHRALFT 933
Query: 677 YGSQHEQAHSTGTVPGHIPSTVQAQS-QPHGVYPPSSVAQGQSQGQPSSS-SLTGVSSSQ 734
S+H+ V G I ++ QP +Y Q + SSS S T V +
Sbjct: 934 SKSEHKD-----VVDGKISECASVETKQPAILYQVEDNRQIMAPVTNSSSYSTTSVRAV- 987
Query: 735 PIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQ 778
P + +G+ + A V Y QT++ ++A + P Q
Sbjct: 988 ----PAECEGLTKQASIFIPV-YPCHQTASQADALMSHPGESTQ 1026
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 619 bits (1595), Expect = e-176
Identities = 409/975 (41%), Positives = 516/975 (52%), Gaps = 101/975 (10%)
Query: 97 GLPLSLPQPSIPAAVPQSAPPEPH------REETVTATATSQVAQQPPAAAAPGEQAVAG 150
G P P P A P P R +S PA P AG
Sbjct: 32 GQPRLGPPPRRARRFSGKAEPRPRSSRLSRRSSVDLGLLSSWSLPASPAPDPPDPPDSAG 91
Query: 151 PAPSTVPSSTSKDRPVSQ-----PSLVGSKEEPPPARSGSGGGSAKEPQE-------ERS 198
P P+ P +SK+ P P P + G ++EP ER
Sbjct: 92 PGPARSPPPSSKEPPEGTWTEGAPVKAAEDSARPELPDSAVGPGSREPLRVPEAVALERR 151
Query: 199 QQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLT 258
++Q++ E++ET+AV S DGR+LKFDIEIGRGSFKTVY+GLDT+TTVEVAWCELQ RKL+
Sbjct: 152 REQEEKEDMETQAVATSPDGRYLKFDIEIGRGSFKTVYRGLDTDTTVEVAWCELQTRKLS 211
Query: 259 KSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKV 318
++ERQRF EE EMLKGLQHPNIVRFYDSW+S ++G+ CIVLVTELMTSGTLKTYL+RF+
Sbjct: 212 RAERQRFSEEVEMLKGLQHPNIVRFYDSWKSVLRGQVCIVLVTELMTSGTLKTYLRRFRE 271
Query: 319 MKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRAS 378
MK +VL+ W RQIL+GL FLH+R PPI+HRDLKCDN+FITGPTGSVKIGDLGLATLKRAS
Sbjct: 272 MKPRVLQRWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPTGSVKIGDLGLATLKRAS 331
Query: 379 FAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG 438
FAKSVIGTPEFMAPEMYEEKYDE+VDVYAFGMCMLEMATSEYPYSECQNAAQIYR+VTSG
Sbjct: 332 FAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSG 391
Query: 439 VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKI 498
KP SF KV IPEVKEIIEGCIR +K+ER++I+DLL HAFF+EE GV VELAEEDDGEK
Sbjct: 392 RKPNSFHKVKIPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREERGVHVELAEEDDGEKP 451
Query: 499 AIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAI 558
+KLWLR+ED ++ G+ +DN+AIEF F L RD E+VAQEMV G VCE D++ +A+A+
Sbjct: 452 GLKLWLRMEDARR-GGRPRDNQAIEFLFQLGRDAAEEVAQEMVALGLVCEADYQPVARAV 510
Query: 559 KDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTAST 618
++RV+ I+RKRE+ + RE ++ LP G P A+
Sbjct: 511 RERVAAIQRKREKLRKARE-------------------------LEALP-PEPGPPPATV 544
Query: 619 TSASVSTQV---EPEEPEADQHQQLQYQQPSI-SVLSDGTVDSGQGSSVFTESRVSSQQT 674
A V EPEEPEADQHQ ++ S S SD D SS F ++ + Q
Sbjct: 545 PMAPGPPSVFPPEPEEPEADQHQPFLFRHASYSSTTSDCETDGYLSSSGFLDASDPALQP 604
Query: 675 VSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQ 734
G A S +P ++ P S A + G G
Sbjct: 605 PG-GVPSSLAESHLCLPSAFALSIPRSGPGSDFSPGDSYASDAASGLSDVGEGMGQMRRP 663
Query: 735 P----IQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQ--------- 781
P + P+ + + + V QT S T + +
Sbjct: 664 PGRNLRRRPRSRLRVTSVSDQNDRVVECQLQTHNSKMVTFRFDLDGDSPEEIAAAMVYNE 723
Query: 782 -VLPQVSAG---KQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLP 837
+LP G + + Q V T+ P+ + P +P P P LP
Sbjct: 724 FILPSERDGFLRRIREIIQRVETLLKRDTGPMEAAEDTLS--------PQEEPAPLPALP 775
Query: 838 QYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPG--VSTVVPSQ 895
+P+ P Q+ S + A T +SS T PG S P
Sbjct: 776 ------VPLPDPSNEELQSSTSLEHRSWTA-----FSTSSSSPGTPLSPGNPFSPGTPIS 824
Query: 896 LPTLLQPVTQLPSQVHPQLLQP-AVQSMGIPANLGQAAEVPLSS---------GDVLYQG 945
P + P+T P P P + Q P+ ++ +P SS +
Sbjct: 825 -PGPIFPITSPPCHPSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSS 883
Query: 946 FPPRLPPQY-PGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLL 1004
P PP + P S + SS C ++ +L+ F V +S LL
Sbjct: 884 LPTTSPPTFSPTCSQVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQS-LL 942
Query: 1005 VPMGGVGGQVQVSQP 1019
P G+ Q + P
Sbjct: 943 SPSPGLLSQSPPAPP 957
Score = 127 bits (320), Expect = 1e-28
Identities = 126/458 (27%), Positives = 193/458 (42%), Gaps = 92/458 (20%)
Query: 1031 SQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSV------------DSAHSDVASG 1078
S L+++ Q P ++A++ P+ A S+ DS SD ASG
Sbjct: 590 SSSGFLDASDPALQPPGGVPSSLAESHLCLPSAFALSIPRSGPGSDFSPGDSYASDAASG 649
Query: 1079 MSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLE 1138
+SD E + R GR +R R RSR LR+ +VS++ DRVVECQL+
Sbjct: 650 LSDVGEGM-GQMRRPPGRNLRR------RPRSR--------LRVTSVSDQNDRVVECQLQ 694
Query: 1139 THNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSV 1198
THN KMVTF+FDLDGD+PEEIA MV N+FIL ER+ F+ ++REII++ + +L D
Sbjct: 695 THNSKMVTFRFDLDGDSPEEIAAAMVYNEFILPSERDGFLRRIREIIQRVETLLKRDTGP 754
Query: 1199 EPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRF 1258
+ L + +P P ++P + P++ Q
Sbjct: 755 MEAAEDTLSPQE------------------EPAPLPALPVPLPDPSNEELQ--------- 787
Query: 1259 IVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEG 1318
S E + + + T + + T SPG N + +S F
Sbjct: 788 ------SSTSLEHRSWTAFSTSSSSPGTPLSPG-NPFSPGTPISPGPIF----------- 829
Query: 1319 PNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVP 1378
P T+PP H P+ P S ++ P+ ++P+P +SS P E VP
Sbjct: 830 PITSPP--CHPSPS--PFSPISSQVSSNPSPHPTSSPLPFSSSTP----------EFPVP 875
Query: 1379 TEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPT--S 1436
+ +T T SP S+ + P+ +T +P L + + S
Sbjct: 876 LSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTSSFPS----TTAAPLLSLASAFS 931
Query: 1437 TSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAV 1474
+ + V+ + L PS + + S A S P PP V
Sbjct: 932 LAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPV 969
Score = 105 bits (262), Expect = 5e-22
Identities = 133/469 (28%), Positives = 192/469 (40%), Gaps = 59/469 (12%)
Query: 1706 TTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVG 1765
+TS+ P T L G P TP+ +PG P+ TS P PS P + P+
Sbjct: 801 STSSSSPGTPLSPGNPFSPGTPI-SPG----PIFPITS---PPCHPSPSPFS-----PIS 847
Query: 1766 TELPAGTLPSEQLPPFPGPSLTQ------SQQPLEDLDAQLRRTLSPEMITVTSAVGPVS 1819
+++ + P P P S T SQ P L T SP VT + P
Sbjct: 848 SQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLS-SPFF 906
Query: 1820 MAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSED 1879
P+ + T +S LA++ V + + +S + +
Sbjct: 907 PPCPSTSSFPSTTAAPLLS-------LASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSP 959
Query: 1880 AKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQ 1939
S+ + S SP + V+ E + P + +P A SE G+
Sbjct: 960 LPSLPLPPPVAPGGQ-ESPSPHTAEVESEAS----PPPARPLPGEARLAPISEE----GK 1010
Query: 1940 PTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEG-PVASPPFMDLEQAVLPAVIPKKEK 1998
P VGRFQVT++ + T ++ + K P + D E +
Sbjct: 1011 PQLVGRFQVTSSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTEDSAGGG------- 1063
Query: 1999 PELSEPSHLNGPSSDPEAAFLSRDVDDGSGSP--HSPHQLSSKSLPSQNLSQSLSNSFNS 2056
PE E + +++ A + + DDG SP LS S N S S +
Sbjct: 1064 PETREALAESDRAAEGLGAGVEEEGDDGKEPQVGGSPQPLSHPSPVWMNYSYS-----SL 1118
Query: 2057 SYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPP 2116
S ++ES EDE+ EL+ LR KHL E++ LQ+ QK EIE LY++LGK PP I+ P
Sbjct: 1119 CLSSEESESSGEDEEFWAELQSLRQKHLSEVETLQTLQKKEIEDLYSRLGKQPPPGIVAP 1178
Query: 2117 AAPLSGRRRRPTKSKGS-KSSRSSSLGNKSPQLSG-----NLSGQSAAS 2159
AA LS R+RR SKGS +SR +SL P G +LSG S S
Sbjct: 1179 AAMLSSRQRR--LSKGSFPTSRRNSLQRSEPPGPGIMRRNSLSGSSTGS 1225
Score = 48.1 bits (113), Expect = 1e-04
Identities = 87/338 (25%), Positives = 127/338 (37%), Gaps = 56/338 (16%)
Query: 1534 HSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGP-TSTP 1592
H S T + S S+P + SPG S PG TPI P P TS P
Sbjct: 794 HRSWTAFSTSSSSPGTPLSPGNPFS-----PG-------------TPISPGPIFPITSPP 835
Query: 1593 LLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQ----PHTHCPEVDSDTQPKAPG 1648
P P+ V++ P+ T S P P P + CP S +P
Sbjct: 836 CHPSPSPFSPISSQVSSNPSPHPT---SSPLPFSSSTPEFPVPLSQCPW--SSLPTTSPP 890
Query: 1649 IDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTA---VAPSKLLTS 1705
+ L S F S + S + L + S + + T A ++PS L S
Sbjct: 891 TFSPTCSQVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLS 950
Query: 1706 TTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVG 1765
+ PP+ LP +LP+ P V PG +P P TA + + P P+
Sbjct: 951 QSPPA-PPSPLP----SLPLPPPVAPGGQESP--------SPHTAEVESEASPPPARPLP 997
Query: 1766 TELPAGTLPSEQLPPFPGP-SLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVS--MAA 1822
E + E P G +T S++P E L L P T++ + P + + +
Sbjct: 998 GEARLAPISEEGKPQLVGRFQVTSSKEPAEPL------PLQPTSPTLSGSPKPSTPQLTS 1051
Query: 1823 PTAITE--AGTQPQKGVSQVKEGPVLATSSGAGVFKMG 1858
++ TE AG P+ + E A GAGV + G
Sbjct: 1052 ESSDTEDSAGGGPETR-EALAESDRAAEGLGAGVEEEG 1088
Score = 47.0 bits (110), Expect = 2e-04
Identities = 54/233 (23%), Positives = 87/233 (37%), Gaps = 24/233 (10%)
Query: 1398 LPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATS 1457
+P+P S + SS +S+ + + ST+S S P S T + P TS
Sbjct: 776 VPLPDPSNEELQSS--TSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTPISPGPIFPITS 833
Query: 1458 ASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSV---STTTSFPSTASQLSIQLSSSTS 1514
P P P + +S Q + + + T + + S+T FP SQ +TS
Sbjct: 834 PPCH-----PSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTS 888
Query: 1515 TPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVI-- 1572
PT + T T F PS+SS P + +S V+
Sbjct: 889 PPTFS-----------PTCSQVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTV 937
Query: 1573 -PSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQP 1624
S+++ +P L + P LP +P PP+ P+ + S+ P
Sbjct: 938 AQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEVESEASP 990
Score = 42.7 bits (99), Expect = 0.004
Identities = 90/447 (20%), Positives = 151/447 (33%), Gaps = 94/447 (21%)
Query: 518 DNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVRE 577
+++ + F FDL+ D PE++A MV + ++ + + I++ + ++ L++
Sbjct: 697 NSKMVTFRFDLDGDSPEEIAAAMVYNEFILPSERDGFLRRIREIIQRVET------LLKR 750
Query: 578 EQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQH 637
+ + E +L Q E + LP+ +P S ST +E A
Sbjct: 751 DTGPMEAAEDTLSPQEEPAP--------LPALPVPLPDPSNEELQSSTSLEHRSWTAF-- 800
Query: 638 QQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPST 697
S S S GT S PG+ P +
Sbjct: 801 --------STSSSSPGTPLS---------------------------------PGN-PFS 818
Query: 698 VQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSS---SQPIQHPQQQQGIQQTAPPQQT 754
P ++P +S PS S + +SS S P HP ++ P+
Sbjct: 819 PGTPISPGPIFPITS-----PPCHPSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFP 873
Query: 755 VQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPS 814
V LSQ SS TT+ P P QV P + P+ P + +A+ S
Sbjct: 874 VP--LSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFS 931
Query: 815 VVPVHSGAHFLPVGQPL--PTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQP 872
+ + L L +P P P+ +P+ P Q S T
Sbjct: 932 LAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSP--------HTAE 983
Query: 873 LLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAA 932
+ + AS +PG + + P + + PQL V + ++ A
Sbjct: 984 VESEASPPPARPLPGEARLAP------------ISEEGKPQL----VGRFQVTSSKEPAE 1027
Query: 933 EVPLSSGDVLYQGFPPRLPPQYPGDSN 959
+PL G P PQ +S+
Sbjct: 1028 PLPLQPTSPTLSGSPKPSTPQLTSESS 1054
Score = 33.1 bits (74), Expect = 3.3
Identities = 31/93 (33%), Positives = 37/93 (39%), Gaps = 6/93 (6%)
Query: 95 LPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQ--VAQQPPAAAAPGEQAVAGPA 152
LP LP+ LP PS QS+ HR T +T++S P +PG GP
Sbjct: 771 LPALPVPLPDPSNEEL--QSSTSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTPISPGPI 828
Query: 153 -PSTVPSSTSKDRPVSQ-PSLVGSKEEPPPARS 183
P T P P S S V S P P S
Sbjct: 829 FPITSPPCHPSPSPFSPISSQVSSNPSPHPTSS 861
Score = 32.7 bits (73), Expect = 4.4
Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 21/116 (18%)
Query: 95 LPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPS 154
LP LPL P P P P PH TA S+ A PPA PGE +A
Sbjct: 960 LPSLPL--PPPVAPGG---QESPSPH-----TAEVESE-ASPPPARPLPGEARLA----- 1003
Query: 155 TVPSSTSKDRPVSQPSLVGSKE--EPPPAR--SGSGGGSAKEPQEERSQQQDDIEE 206
S K + V + + SKE EP P + S + GS K + + + D E+
Sbjct: 1004 -PISEEGKPQLVGRFQVTSSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTED 1058
>gi|7019333 nuclear receptor binding protein [Homo sapiens]
Length = 535
Score = 144 bits (364), Expect = 8e-34
Identities = 111/333 (33%), Positives = 162/333 (48%), Gaps = 27/333 (8%)
Query: 155 TVPSSTSKDRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGM 214
TV SS S + S S G PP S + SA P+EE + +D+ E LE
Sbjct: 8 TVLSSGSDPKVESSSSAPGLTSVSPPVTSTT---SAASPEEEE-ESEDESEILEE----- 58
Query: 215 SNDGRFLKFDIEIGRGS---FKTVYKGLDTETTVEVAWCELQ--DRKLTKSERQRFKEEA 269
S GR+ K E+ + + + Y +DTE VEV W E+Q +RK K + ++ +
Sbjct: 59 SPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVF 118
Query: 270 EMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKR----FKVMKIKVLR 325
+ L L+H NIV+F+ W + K ++ +TE M+SG+LK +LK+ K M K +
Sbjct: 119 DNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWK 178
Query: 326 SWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL-KRASFAKSVI 384
WC QIL L +LH+ PPIIH +L CD IFI G +KIG + T+ +
Sbjct: 179 RWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQ-HNGLIKIGSVAPDTINNHVKTCREEQ 237
Query: 385 GTPEFMAPEMYE-EKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPAS 443
F APE E +VD+Y+FGMC LEMA E N Y V ++
Sbjct: 238 KNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQ----GNGESSY--VPQEAISSA 291
Query: 444 FDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNH 476
+ P +E I+ C++ R + ++LL H
Sbjct: 292 IQLLEDPLQREFIQKCLQSEPARRPTARELLFH 324
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 138 bits (347), Expect = 7e-32
Identities = 342/1608 (21%), Positives = 565/1608 (35%), Gaps = 192/1608 (11%)
Query: 587 SSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPS 646
SS E +S + + + +A T IP ++TT AS P Y Q S
Sbjct: 1493 SSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQAS 1552
Query: 647 IS-VLSDGTVDS----GQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQ 701
S +DGT +GS+ T VS+ VS +A++ T P + V A
Sbjct: 1553 SSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVS-----SEANTLSTTPIDSKTQVTAS 1607
Query: 702 SQPHGVYPPSSVAQGQSQ--GQPSSSS--LTGVS-SSQPIQHPQQQQGIQQTAPPQQTVQ 756
++ S+ A+G S PS S LT + S+ P+ P+ + P +
Sbjct: 1608 TEASS----STTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEAST---LSTTPVDSNS 1660
Query: 757 YSLSQTSTSSEATTAQPVSQPQAPQV-----LPQVSAGKQLPVSQPVPTIQGEP-----Q 806
++ T SS T A+ S P + L ++ S + T+ P
Sbjct: 1661 PVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTP 1720
Query: 807 IPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPIST-PHVSTAQTGFSSLPI-- 863
+ +T+ P S P TP P++ IP+ST P +S+ + S+ PI
Sbjct: 1721 VTTSTEARSSPTTSEG----TSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDT 1776
Query: 864 --------------TMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQ 909
T A G + P TL+ T VS + + T + S
Sbjct: 1777 STPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSN 1836
Query: 910 VHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNI---APSSNV 966
P + AV S PA A S G P ++N P+
Sbjct: 1837 -SPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTS 1895
Query: 967 ASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQA 1026
V ++ V S P + + P P +P + S + ++ + +
Sbjct: 1896 TPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRT 1955
Query: 1027 PTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQ-PTTLASSVDSAHSDVASGMSDGNEN 1085
P T+ QA T P + T T P + V S S +++ D +
Sbjct: 1956 PVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTP 2015
Query: 1086 VPSSSGRHEGRTTKRHYRKSVRSRSRHEKTS----RPKLRILNVSNKGDRV----VECQL 1137
+S+ TT S+++ + E+T+ P L VS++G+ + V+ +
Sbjct: 2016 ATTSTEGSSSPTTAGG--TSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKT 2073
Query: 1138 ETHNRKMVTFKFDLDGDN-----PEE----IATIMVNNDFILAIERESFVDQVREIIEKA 1188
+ N + +G + P E + +I ++ + + E + + +
Sbjct: 2074 QVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTL--STTPVDSNS 2131
Query: 1189 DEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLT 1248
+ S +VS P +G S + + P +SMP + SS
Sbjct: 2132 PVITSTEVSSSPIPTEGT-------------SMQTSTYSDRRTPLTSMPVSTTVVASSAI 2178
Query: 1249 QVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFS 1308
+ + + + P + E++ P+ T ++ S G S ++ S
Sbjct: 2179 STLSTTP---VDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTS 2235
Query: 1309 ELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDIST 1368
E T + P S + P S +PT+ + P TS P + T
Sbjct: 2236 EASTLSATPVDTSTPVTTSTEATSSPTTAEGTS----IPTSTLSEGTTPLTSIPVSH--T 2289
Query: 1369 SVIQSEVTV----------------------PTEEGIAGVATSTGVVTSGGLPIPPVSES 1406
V SEV+ PT EG + + TST + L PVS +
Sbjct: 2290 LVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTS-MPTSTSSEGNTPLTRMPVSTT 2348
Query: 1407 PVLSSVVSSI-TIPAVVSIS-----------TTSPSLQVPTSTSEIVVSSTALYPSVTVS 1454
V S S++ T PA S TT+ +PTST + P T+
Sbjct: 2349 MVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMP 2408
Query: 1455 ATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSS--- 1511
S+ A + TP V + A S+ A TS+ T+ T S+ +S+
Sbjct: 2409 VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPV 2468
Query: 1512 -STSTPTLAETVV-VSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHP 1569
S+ TL+ T V S T SS+ A + P S++S G+ + + I P P
Sbjct: 2469 VSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSI--PVSTTP 2526
Query: 1570 LVIP--SVIASTPILPQAAGPTSTPLLPQVP---------------SIPPLVQPVANVP- 1611
+ P S +++TP+ + TST + S P PV+ P
Sbjct: 2527 VASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586
Query: 1612 -AVQQTLIHSQPQPALLPNQPHTH---CPEVDSDTQPKAPGIDDIKT-LEEKLRSLFSEH 1666
+ + + + + P +P T P DT ++ T L L S
Sbjct: 2587 ASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVA 2646
Query: 1667 SSSGAQHASVSLET-SLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPV 1725
SS + ++ ++T +LV ST T PTTA S ++ P TN+ + T L
Sbjct: 2647 SSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLAN 2706
Query: 1726 TPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGT-LPSEQLPPFPGP 1784
+ T +TPV T+T A S P + + + T T L S + P
Sbjct: 2707 SEASTLS--TTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVA 2764
Query: 1785 SLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGP 1844
S S +D + T S E + + SM PT+ + P + V P
Sbjct: 2765 SSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSM--PTSTPSETSTPLTSM-PVNHTP 2821
Query: 1845 VLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPEST- 1903
V SS AG S + K + + V S+ SE S L +S P ST
Sbjct: 2822 V--ASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTT 2879
Query: 1904 -LVKPEPNGITIPGISSDVP------ESAHKTTASEAKSDTGQPTKVGR-------FQVT 1949
+ E + ++ + + +P S+ TTA P++V V
Sbjct: 2880 PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP 2939
Query: 1950 TTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNG 2009
++ S + + + T +SP E +P P + + L+ S
Sbjct: 2940 VAGSEASTLSTTPVDTRTPVTTSAEASSSP--TTAEGTSMPISTPGERRTPLTSMSVSTM 2997
Query: 2010 PSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSS 2057
P + EA+ LSR D S + + SS ++ +S S
Sbjct: 2998 PVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045
Score = 137 bits (345), Expect = 1e-31
Identities = 329/1542 (21%), Positives = 543/1542 (35%), Gaps = 223/1542 (14%)
Query: 594 EQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDG 653
E S+ S T + A+T +S+ + + T ++ P +++ L S +++
Sbjct: 2001 EASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP-SERTTPLAGMPVSTTLVVSS 2059
Query: 654 TVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSV 713
++ + V ++++V++ S + E + T + P + S P P +S
Sbjct: 2060 EGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSE--GSPLLTSIPLSTTPVASP 2117
Query: 714 AQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQ------------TAPPQQTVQYSLSQ 761
P S+ ++S++ P +G T+ P T + S
Sbjct: 2118 EASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSA 2177
Query: 762 TSTSSEAT--TAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVH 819
ST S T+ PV+ + P S G +P S P +PV+T P V
Sbjct: 2178 ISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEA 2237
Query: 820 SGAHFLPVGQPLPTPLLPQYPVS-------QIPISTPHVSTAQTGFSSLPITMAAGITQP 872
S PV P + S IP ST +S T +S+P++
Sbjct: 2238 STLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTST--LSEGTTPLTSIPVSHTLVANSE 2295
Query: 873 LLTLASSATTAAIPGVSTVVPSQLPTLLQ--------------PVTQLP------SQVHP 912
+ TL+++ + P ++ S P + P+T++P +
Sbjct: 2296 VSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFET 2355
Query: 913 QLLQPAVQSMGIPANL-GQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVC- 970
L P QA P ++ D P + P S + V
Sbjct: 2356 STLSTTPADTSTPVTTYSQAGSSPTTADDT---SMPTSTYSEGSTPLTSVPVSTMPVVSS 2412
Query: 971 ---IHSTV---LSPPMPTEVLATPGYFPTVVQ-------PYVESNLLVPMGGVGGQVQVS 1017
HST S P+ T A+ PT + P E + V VS
Sbjct: 2413 EASTHSTTPVDTSTPVTTSTEASSS--PTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVS 2470
Query: 1018 QPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVAS 1077
G+L+ P +S + ST+ S AE + V + A++ +TL +S+ + + VAS
Sbjct: 2471 SEAGTLSTTPVDTSTP-MTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVAS 2529
Query: 1078 GMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQL 1137
+ P S +T+ S + E TS P + ++G
Sbjct: 2530 PEASTLSTTPVDSNSPVVTSTEIS-----SSATSAEGTSMPT----STYSEGS------- 2573
Query: 1138 ETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVS 1197
T R M L ++T V+ + E+ + S +S
Sbjct: 2574 -TPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTA------KDTSMPIS 2626
Query: 1198 VEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRR 1257
E L S+ P+ +S P + T V S G
Sbjct: 2627 TPSEVSTSLTSILVST---------------MPVASSEASTLSTTPVDTRTLVTTSTGTS 2671
Query: 1258 FIVSPVPESRLRESKVFPSE----ITDTVAAST--AQSPGMNLSHSASSLSLQQAFSELR 1311
+ S + S P E +T+ + ++T A S LS + S S
Sbjct: 2672 SSPTTAEGSSMPTST--PGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTS--- 2726
Query: 1312 RAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVI 1371
A+ + P TA G + + P S P T+ + +P SS + +ST+ +
Sbjct: 2727 -AEASSSPTTAE------GTSMRISTP---SDGSTPLTSILVSTLPVASSEASTVSTTAV 2776
Query: 1372 QSEVTV---------PTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVV 1422
+ + V PT + + TST TS L PV+ +PV SS ++
Sbjct: 2777 DTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTL------ 2830
Query: 1423 SISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGS 1482
STT P +TS SS + V ++AS G + T P V+ A +
Sbjct: 2831 --STTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAST 2888
Query: 1483 TTVGATLTSVSTTT-----SFPSTASQLSIQLSSSTSTPTLAETVVVS--------AHSL 1529
+ TS+ TT S P+TA S+ +S+ + T +++VS A +L
Sbjct: 2889 LSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTL 2948
Query: 1530 DKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPT 1589
T + T + S A SSS + G S IS PG P S +P A+
Sbjct: 2949 STTPVDTRTPVTTSAEA-SSSPTTAEGTSMPISTPGERR---TPLTSMSVSTMPVASSEA 3004
Query: 1590 STPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGI 1649
ST L + P+ + + T P P++ T + T P A I
Sbjct: 3005 ST--LSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA--I 3060
Query: 1650 DDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTST 1709
+ TL S+ ++ + TS + S+ TP T+ + ST T
Sbjct: 3061 PEASTL------------STTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLT 3108
Query: 1710 CLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGT--- 1766
+P + P+ + A+ T TP STPV+T+T A S P ++ +P T
Sbjct: 3109 GVPVSTTPVTSSAIS-TLSTTPVDTSTPVTTSTE------AHSSPTTSEGTSMPTSTPSE 3161
Query: 1767 -ELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTA 1825
P +P + T S P +D T S E + T+A G + PT+
Sbjct: 3162 GSTPLTYMPVSTMLVVSSEDSTLSATP---VDTSTPVTTSTEATSSTTAEG---TSIPTS 3215
Query: 1826 ITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHF 1885
G P V V PV SS A + + D S +
Sbjct: 3216 TPSEGMTPLTSV-PVSNTPV--ASSEASILS------TTPVD---------SNTPLTTST 3257
Query: 1886 ESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGR 1945
E+S+S + +S P ST + ++P +S+ S+ +T S +DT P
Sbjct: 3258 EASSSPPTAEGTSMPTSTPSEGSTPLTSMP-VSTTTVASSETSTLSTTPADTSTP----- 3311
Query: 1946 FQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPS 2005
VTT + ++ T T EG S P ++ + P V+ + + P
Sbjct: 3312 --VTTYSQASSSPPIADGTSMPTSTYSEG---STPLTNMSFSTTP-VVSSEASTLSTTPV 3365
Query: 2006 HLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLS 2047
+ P + A LS +G+ P S + L S +S
Sbjct: 3366 DTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVS 3407
Score = 131 bits (330), Expect = 7e-30
Identities = 371/1880 (19%), Positives = 652/1880 (34%), Gaps = 219/1880 (11%)
Query: 585 EESSLKQQVEQSSASQTGIKQLPSAS--TGIPTASTTSASVSTQVEPEEPEADQHQQLQY 642
E +S++ V + + + P+ S T T+ +T+ S+ + P + +
Sbjct: 90 EMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPM 149
Query: 643 QQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQS 702
PS +S E+ S ++Y +T T P+T ++ +
Sbjct: 150 STPSEESISSTMAFVSTAPLPSFEAYTS----LTYKVDMSTPLTTSTQASSSPTTPESTT 205
Query: 703 QPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQT 762
P S+ ++G + +S V+SS+ I T P + + ++S
Sbjct: 206 -----IPKSTNSEGSTPLTSMPASTMKVASSEAIT--------LLTTPVEISTPVTISAQ 252
Query: 763 STSSEATTAQPVSQPQAPQ----VLPQVSAGKQLPVSQPVPTIQGEP---QIPVATQPSV 815
++SS T P AP L ++ L VS T+ P IPV T
Sbjct: 253 ASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEA 312
Query: 816 VPVHSGAHFLPVGQPLPTPLLPQ--YPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPL 873
S + G +PT + P++ P ST V+T++ S+L IT T L
Sbjct: 313 ----SSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSE--MSTLSITPVD--TSTL 364
Query: 874 LTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVH----PQLLQPAVQSMGIPANLG 929
+T ++ PS LPT + + L S + P P + +
Sbjct: 365 VTTSTE-------------PSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAS 411
Query: 930 QAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAP------SSNVASVCIHSTVLSPPMPTE 983
+ +P+ S + P D++IA S+ + S+ + +T ++ +
Sbjct: 412 TTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASN 471
Query: 984 VLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGG-------SLAQAPTTSSQQAVL 1036
+ TP T V E++ P V + G S++ P SS+ + L
Sbjct: 472 LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTL 531
Query: 1037 ESTQGVSQVAPAEPVAVAQTQATQP--TTLASSVDSAHSDVASGMSDGNENVPSSSGRHE 1094
ST V P + A + +T P T++ +S S S + M V SS
Sbjct: 532 -STTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTT 590
Query: 1095 GRT---TKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDL 1151
T + S + S + S +G + + T +
Sbjct: 591 STTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTL---------V 641
Query: 1152 DGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQG 1211
++T V+++ + E+ E S S EG L S+
Sbjct: 642 ASSEASTLSTTPVDSNTPVTTSTEATSSST------TAEGTSMPTSTYTEGSTPLTSMPV 695
Query: 1212 KDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRES 1271
S + P+ S+ P SS A + L
Sbjct: 696 NTT--LVASSEASTLSTTPVDTST-PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSM 752
Query: 1272 KVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGP 1331
V + +T + A++ + +P +H +S + TEG + S P
Sbjct: 753 PVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS------PTTTEGTSMPISTPSEGSP 806
Query: 1332 TFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTG 1391
+P ++ + + +T PV + S ++TS S P E G + T
Sbjct: 807 LLTSIPVSITPVTSPEASTLSTTPVDSNS----PVTTSTEVSSSPTPAE----GTSMPTS 858
Query: 1392 VVTSGGLPIP--PVSESPVLSSVVSSITIPAV------------VSISTTSPSLQVPTST 1437
+ G P+ PVS + V +S +S+++ V S TTS +PTST
Sbjct: 859 TYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 918
Query: 1438 SEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTT- 1496
+ P T S+ A +ATP V + A S+ A TS+ T+T
Sbjct: 919 PGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP 978
Query: 1497 ---SFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSST-----TGLAFSLSAPS 1548
+ P T++ +S L +++ TL+ T V S L ++ +S+ G + S PS
Sbjct: 979 SEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPS 1038
Query: 1549 SSSSP--GAGVSSYISQPGGLHPLVIPSVIASTPI--LPQAAGPTSTPLLPQVP--SIPP 1602
S+P VS+ + L STP+ QA+ ++T +P +
Sbjct: 1039 EGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSE 1098
Query: 1603 LVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSL 1662
P+ +VP V L+ S L T P S +P T E
Sbjct: 1099 GSTPLTSVP-VSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSP------TTAEGTSIP 1151
Query: 1663 FSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVA 1722
S S AS+ + T+LV+ S T + +++ TST ++ PP T
Sbjct: 1152 TSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPP------TAE 1205
Query: 1723 LPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPV---LPVGTELPAGTLP-SEQL 1778
+ P TPG+ STP+++ P + L+ +PV PV T + P + +
Sbjct: 1206 VTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEG 1265
Query: 1779 PPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAIT-EAGTQPQKGV 1837
P + ++ L + SPE T+ + PV P + E + P
Sbjct: 1266 TSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTT--PVDTKGPVVTSNEVSSSPT--- 1320
Query: 1838 SQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTS-ESSVLS 1896
P TS + GR ++ + + ++ST +S +
Sbjct: 1321 ------PAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEA 1374
Query: 1897 SSSPESTLVKPEPNGITIPGIS--SDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANK 1954
SSP ++ PN G + + +P S +SEA + + P TT+A
Sbjct: 1375 CSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTST-PGTTSAEA 1433
Query: 1955 VGRFSVSKTEDKITDTKKEG-------PVASPPFMDLEQAVLPAVIPKKEKPELSEPSHL 2007
+ ++ T T EG PV++ P + E + L P ++ +
Sbjct: 1434 TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVS 1493
Query: 2008 NGPSSDPEAAFLSRDVDDGSGS----PHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDN 2063
+ P+ + +GS + P S ++S + S + + +++++ ++Y + +
Sbjct: 1494 SSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASS 1553
Query: 2064 ESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGR 2123
D S Q T L +P + ++ ++ +
Sbjct: 1554 SPTTADG--------------------TSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTL 1593
Query: 2124 RRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQ 2183
P SK + +S+ + S G+ S S P T P P +
Sbjct: 1594 STTPIDSKTQVT--ASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTL 1651
Query: 2184 PLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTS---STNTVGATVNSQAAQAQPPAMTS 2240
P S+ + + + V S P +GTS ST T G T + P +S
Sbjct: 1652 STTPVDSNSPVIT------STEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASS 1705
Query: 2241 SRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKFSAPGQLCISMTSNLG 2300
+ T VDN + R EG M S P + +TS
Sbjct: 1706 AISTLSTTP----VDNSTPVTTSTEAR---SSPTTSEGTSMPN--STPSEGTTPLTSIPV 1756
Query: 2301 GSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGTGGPAPQPLGQFQPVGTASLQ 2360
+ P+ ++ A++L P AT GT P P+ + +
Sbjct: 1757 STTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVS 1816
Query: 2361 NFNISNLQKSI--SNPPGSN 2378
+ ++N + S + P SN
Sbjct: 1817 HTLVANSEASTLSTTPVDSN 1836
Score = 131 bits (329), Expect = 9e-30
Identities = 300/1460 (20%), Positives = 523/1460 (35%), Gaps = 218/1460 (14%)
Query: 599 SQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPS-ISVLSDGTVDS 657
S T + AS+ TA TS ST E S S LS VDS
Sbjct: 597 SNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDS 656
Query: 658 GQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVP---GHIPSTVQAQSQPH--GVYPPSS 712
+ TE+ SS T S ++ G+ P + +T+ A S+ P +
Sbjct: 657 NTPVTTSTEA-TSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDT 715
Query: 713 VAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSL-SQTSTSSEATTA 771
+ + SSS T +S P P + + P +T+ S + T +++ T+
Sbjct: 716 STPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTS 775
Query: 772 QPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEP---QIPVATQPSVVPVHSGAHFLPVG 828
++ P + G +P+S P +G P IPV+ P P S PV
Sbjct: 776 THITTSTEASCSPTTTEGTSMPISTPS---EGSPLLTSIPVSITPVTSPEASTLSTTPVD 832
Query: 829 QPLPTPLLPQYPVSQIP-----ISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTA 883
P + S P + T S +T +S+P++ T + TL+++
Sbjct: 833 SNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDT 892
Query: 884 AIPGVSTVVPSQLPTLLQ--------------PVTQLPSQVHPQLLQPAVQSMGIPANLG 929
+ P ++ PT + P+T +P P + A P +
Sbjct: 893 STPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTS 952
Query: 930 QAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPG 989
+ +P P + ++ + S + T+++ + + TP
Sbjct: 953 TPVTTSTEATSSPTTAEGTSIPTSTPSEG----TTPLTSTPVSHTLVANSEASTLSTTP- 1007
Query: 990 YFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAE 1049
V+SN + + G S+ + + + + VA +E
Sbjct: 1008 ---------VDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSE 1058
Query: 1050 PVAVAQTQATQPTTLAS-SVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRS 1108
++ T A T + + S S+ S A G S +P+S+ EG T S R
Sbjct: 1059 TSTLSTTPADTSTPVTTYSQASSSSTTADGTS-----MPTST-YSEGSTPLTSVPVSTRL 1112
Query: 1109 RSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDF 1168
E ++ + + S E + + + +A++ V+
Sbjct: 1113 VVSSEASTLSTTPV-DTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTL 1171
Query: 1169 ILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFK 1228
+++ E + + K S + S P + S +
Sbjct: 1172 VVSSEANTL--STTPVDSKTQVATSTEASSPPPTAEVT-------------SMPTSTPGE 1216
Query: 1229 QPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPV----PESRLRESKVFPSEITDTVAA 1284
+ P +SMP + T V S SPV P + E+ P+ T
Sbjct: 1217 RSTPLTSMPVRH-------TPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLP 1269
Query: 1285 STAQSPGMNLSHS----ASSLSLQQAFSELRRAQMTEGP-------NTAPPNFSHTGPTF 1333
++ S G L S + ++ +A + L T+GP +++P T
Sbjct: 1270 TSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPT 1329
Query: 1334 PVVPPFLSSIAGVP--TTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTG 1391
+ + +P TT A++ + S+ P D ST V S + G +
Sbjct: 1330 STYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS 1389
Query: 1392 VVTSGGLPIP--PVSESPVLSSVVSSITIPAV------------VSISTTSPSLQVPTST 1437
+ G P+ PVS +PV+SS S+++ V S TT+ + +PTST
Sbjct: 1390 NPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTST 1449
Query: 1438 --------SEIVVSSTAL----------------YPSVTVSATSAS---AGGST---ATP 1467
I VS+T + P VT +A S+S A G++ +TP
Sbjct: 1450 PSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTP 1509
Query: 1468 GPKPPAVVSQQAAGSTTVGATLTSVSTT--------------TSFPSTASQLSIQLS--S 1511
A+ S + +T + + S+STT +S P+TA S+Q S S
Sbjct: 1510 SEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYS 1569
Query: 1512 STSTP----TLAETVVVS--AHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPG 1565
STP ++ +VVS A++L T S T + S A SS+++ G+ ++ IS P
Sbjct: 1570 EGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMT--ISTPS 1627
Query: 1566 GLHPLVIPSVIASTPIL-PQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQP 1624
PL+ +++TP+ P+A+ ++TP+ +N P + T + S P P
Sbjct: 1628 EGSPLLTSIPVSTTPVASPEASTLSTTPV-------------DSNSPVITSTEVSSSPTP 1674
Query: 1625 ALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVI 1684
A + P + T+ + P S S S++ +++ V
Sbjct: 1675 AEGTSMP------TSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTP------VT 1722
Query: 1685 ESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVAL----PVTPVVTPGQVSTPVST 1740
ST PTT+ S ++ + P T++P+ T + T TP STPV+T
Sbjct: 1723 TSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTT 1782
Query: 1741 TTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQL 1800
+T T +P GT +P TL SE + P ++ + +
Sbjct: 1783 STEA------------TSSPTTAEGTSIPTSTL-SEGMTPLTSTPVSHTLVANSEASTLS 1829
Query: 1801 RRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRF 1860
+ VTS S + A + P +G + + PV T+
Sbjct: 1830 TTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTT----------- 1878
Query: 1861 QVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSD 1920
V+ + + + + + S+S ++ SS P ST + P +IP +S+
Sbjct: 1879 -VASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIP-VSTT 1936
Query: 1921 VPESAHKTTASEAKSDTGQP 1940
S+ T S +DT P
Sbjct: 1937 TVASSEINTLSTTLADTRTP 1956
Score = 131 bits (329), Expect = 9e-30
Identities = 355/1570 (22%), Positives = 561/1570 (35%), Gaps = 225/1570 (14%)
Query: 596 SSASQTGIKQLPSASTGIP-----TASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVL 650
SS T + ++P ++T + T STT A ST V + Q +
Sbjct: 2333 SSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTT-------YSQAGSSPTTADDT 2385
Query: 651 SDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTV--QAQSQPHGVY 708
S T +GS+ T VS+ VS HST V P T +A S P
Sbjct: 2386 SMPTSTYSEGSTPLTSVPVSTMPVVS---SEASTHSTTPVDTSTPVTTSTEASSSP---- 2438
Query: 709 PPSSVAQGQSQGQPSSSSLTGVSSSQPIQHP---QQQQGIQQTAPPQQTVQYSLSQTSTS 765
+ A+G S S T +S P+ + G T P + + S T S
Sbjct: 2439 ---TTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTS-TEAS 2494
Query: 766 SEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFL 825
S TTA+ + P + S G L S PV T P A+ S PV S + +
Sbjct: 2495 SSPTTAEDIVVP-----ISTASEGSTLLTSIPVSTTPVAS--PEASTLSTTPVDSNSPVV 2547
Query: 826 PV-----------GQPLPTPLLPQ--YPVSQIPIST-PHVSTAQTGFSSLPITMAAGITQ 871
G +PT + P+ +P+ST P S+ + S+ P+ + +T
Sbjct: 2548 TSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTT 2607
Query: 872 PLLTLASSATTAAIPGVSTVVPSQLPTLLQP--VTQLP---SQVHPQLLQPAVQSMGIPA 926
T +SS TTA + PS++ T L V+ +P S+ P +
Sbjct: 2608 STET-SSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTT 2666
Query: 927 NLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLA 986
+ G ++ + G +P PG+ S+ + ++ + +T+L+ + +
Sbjct: 2667 STGTSSSPTTAEGS--------SMPTSTPGER----STPLTNILVSTTLLANSEASTLST 2714
Query: 987 TPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVA 1046
TP T V E++ P G +++S P S P TS +L ST
Sbjct: 2715 TPVDTSTPVTTSAEASSS-PTTAEGTSMRISTP--SDGSTPLTS----ILVSTL------ 2761
Query: 1047 PAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNE--NVPSSSGRHEGRTTKRHYRK 1104
PVA ++ T + +S+ S AS E ++P+S+
Sbjct: 2762 ---PVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTP------------- 2805
Query: 1105 SVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMV 1164
S + TS P S++ + ++T + K E I +
Sbjct: 2806 ---SETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIS 2862
Query: 1165 NNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLE 1224
A E + + + + +S P D + + G S E
Sbjct: 2863 T-----ASEGSTLLTSIPVSTTPVASSEASTLSTTPV-DTSIPVTTSTE--GSSSPTTAE 2914
Query: 1225 GEFKQPIPASSMPQQIGIP-TSSLTQVVHSAGRRFIV---------SPVPESRLRESKVF 1274
G PI S P ++ P TS L V AG +PV S S
Sbjct: 2915 GT-SMPI---STPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPT 2970
Query: 1275 PSEITDTVAASTAQ--SPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHT--- 1329
+E T ++ + +P ++S S ++ +A + R T P T S +
Sbjct: 2971 TAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTT 3030
Query: 1330 --GPTFPVVPPFLSS--IAGVP--TTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGI 1383
G P+ P S + +P TT A S+ P D ++ V+ S +
Sbjct: 3031 AEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPA 3090
Query: 1384 AGVATSTGVVTSGGLPIP--PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIV 1441
G + + G P+ PVS +PV SS +S ++STT P +TS
Sbjct: 3091 EGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS--------TLSTTPVDTSTPVTTSTEA 3142
Query: 1442 VSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPST 1501
SS ++ ++ S G + T P +V + + TS TTS +T
Sbjct: 3143 HSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEAT 3202
Query: 1502 ASQLSIQLSSSTSTPTLAETVVVS------------AHSLDKTSHSSTTGLAFSLSAPSS 1549
+S + S TSTP+ T + S A L T S T L S A SS
Sbjct: 3203 SSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEA-SS 3261
Query: 1550 SSSPGAGVSSYISQPG-GLHPL----VIPSVIAS--TPILPQAAGPTSTPL--LPQVPSI 1600
S G S S P G PL V + +AS T L TSTP+ Q S
Sbjct: 3262 SPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSS 3321
Query: 1601 PPLVQ--------------PVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKA 1646
PP+ P+ N+ + T + S L T P S +
Sbjct: 3322 PPIADGTSMPTSTYSEGSTPLTNM-SFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380
Query: 1647 PGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTST 1706
P T E S S AS+ + T+ V+ S V + TT V + L+T++
Sbjct: 3381 P------TTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT-LSTTPVDSNTLVTTS 3433
Query: 1707 TSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPV---LP 1763
T PT + GT P T + STP+S P + L+ PV P
Sbjct: 3434 TEASSSPT-IAEGT----SLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTP 3488
Query: 1764 VGTELPAGTLP-SEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPV-SMA 1821
V T P + P + ++ P + + PL ++ S E T+++ PV S
Sbjct: 3489 VTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT--PVDSNT 3546
Query: 1822 APTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAK 1881
T+ ++A + P QV + S G+ + S D +
Sbjct: 3547 FVTSSSQASSSP--ATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVD-R 3603
Query: 1882 SVHFESSTSESSVLSSSSPE-STLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQP 1940
S +ST +S + + PE TL P+ ++ P + +P S T SEA + + P
Sbjct: 3604 STPVTTSTQSNS--TPTPPEVITLPMSTPSEVSTP--LTIMPVSTTSVTISEAGTASTLP 3659
Query: 1941 TKVGRFQVTTTANKVGRFSVSKTEDKI-TDTKKEGPVASPPFMDLEQAVLPAVIPKKEKP 1999
+T+T + T I T ++ P+ + P V + E
Sbjct: 3660 VDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMP-------VSTTRVTSSEGS 3712
Query: 2000 ELSEPSHLNGP--SSDPEAAFLSRDVDDGSGSPHSPHQLSS-------KSLPSQNLSQSL 2050
LS PS + ++ EA S +D + S P ++S+ + P +S
Sbjct: 3713 TLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESS 3772
Query: 2051 SNSFNSSYMS 2060
+ S S Y S
Sbjct: 3773 TPSIPSVYTS 3782
Score = 128 bits (321), Expect = 8e-29
Identities = 345/1566 (22%), Positives = 541/1566 (34%), Gaps = 213/1566 (13%)
Query: 585 EESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQ 644
E S+L S++ T ++ S+ T A TS ST E P
Sbjct: 822 EASTLSTTPVDSNSPVTTSTEVSSSPT---PAEGTSMPTSTYSEGRTPLTSMPVSTTLVA 878
Query: 645 PS-ISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQH------EQAHSTGTVPGHIPST 697
S IS LS VD+ + TE+R S T S G+ E + ++P
Sbjct: 879 TSAISTLSTTPVDTSTPVTNSTEAR--SSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPV 936
Query: 698 VQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQT-VQ 756
V ++++ P + + + +SS T +S P P + + P T V
Sbjct: 937 VSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVA 996
Query: 757 YSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVV 816
S + T +++ + P++ P + G +P S P ++PV+T
Sbjct: 997 NSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVAS 1056
Query: 817 PVHSGAHFLPVGQPLPTPLLPQYPVS-------QIPISTPHVSTAQTGFSSLPITMAAGI 869
S P P Q S +P ST S T +S+P++ +
Sbjct: 1057 SETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST--YSEGSTPLTSVPVSTRLVV 1114
Query: 870 TQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLG 929
+ TL+++ +IP ++ S PT + T +P+ + P + SM + L
Sbjct: 1115 SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG-TSIPTSPPSEGTTP-LASMPVSTTLV 1172
Query: 930 QAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPG 989
++E S P + V + SPP EV + P
Sbjct: 1173 VSSEANTLS---------------------TTPVDSKTQVATSTEASSPPPTAEVTSMP- 1210
Query: 990 YFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAE 1049
P S L M V S +L+ +P +S V S + S AE
Sbjct: 1211 ----TSTPGERSTPLTSM-PVRHTPVASSEASTLSTSPVDTS-TPVTTSAETSSSPTTAE 1264
Query: 1050 PVAVAQTQATQPTTLASSVDSAHSDVAS--------------GMSDGNENVPSSSGRHEG 1095
++ + ++ +TL +S+ + + V S G + V SS EG
Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEG 1324
Query: 1096 RTTKRHYRKSVRSRSRHEKTSRPKLRILNVSN----------KGDRVVECQLETHNRKMV 1145
+ S S R TS P L S+ V E +
Sbjct: 1325 TSMP----TSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTT 1380
Query: 1146 TFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQG 1205
+ + NP E T + + V + +A + + V G
Sbjct: 1381 SEGTSMPNSNPSEGTTPLTSIP----------VSTTPVVSSEASTLSATPVDTSTPGTTS 1430
Query: 1206 LESLQGKDD-YGFSGSQKLEGEFKQP---IPASSMPQQIGIPTSSLTQVVHSAGRRFIVS 1261
E+ G S E K P IP S+ P ++ T V S S
Sbjct: 1431 AEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSN------S 1484
Query: 1262 PVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNT 1321
PV S S P+E T ++A ST S G S + A SE+ T +
Sbjct: 1485 PVVTSTAVSSSPTPAEGT-SIAIST-PSEGSTALTSIPVSTTTVASSEINSLSTTPAVTS 1542
Query: 1322 APPNFSHTGPTFPVVPPFLS------SIAGVPTTAAATAPVPATSSPPNDISTSVIQS-- 1373
P + P S S P T+ + + SS N +ST+ I S
Sbjct: 1543 TPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKT 1602
Query: 1374 EVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQV 1433
+VT TE + A + + S P SP+L+S+ S T A ST S +
Sbjct: 1603 QVTASTEASSSTTAEGSSMTIS-----TPSEGSPLLTSIPVSTTPVASPEASTLSTT--- 1654
Query: 1434 PTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKP---------PAVVSQQAAGSTT 1484
P ++ V++ST + S T A S ST T G P P S + STT
Sbjct: 1655 PVDSNSPVITSTEVSSSPT-PAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTT 1713
Query: 1485 VGATLTSVSTTT---SFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLA 1541
T V+T+T S P+T+ S+ S+ + T ++ VS + + S+ +
Sbjct: 1714 PVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATP 1773
Query: 1542 FSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIP 1601
S P ++S+ S P IP+ S + P + P S L+ +
Sbjct: 1774 IDTSTPVTTSTEAT------SSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEAST 1827
Query: 1602 PLVQPV-ANVPAVQQTLIHSQPQPA-------LLPNQPHTHCPEVDSDTQPKAPGIDDIK 1653
PV +N P V T + S P PA P++ T + T A +
Sbjct: 1828 LSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTL 1887
Query: 1654 TLEEKLRS----LFSEHSSSGAQHASVSLETSLVIES----TVTPGIPTTAVAPSKLLTS 1705
+ + S +++ SSS S+ TS E T P + TT VA S++ +
Sbjct: 1888 STTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIP-VSTTTVASSEI--N 1944
Query: 1706 TTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTT--TSGVKPGTAPSKPPLTKAPV-- 1761
T ST L T TPV T Q S+ +T TS P + PLT P+
Sbjct: 1945 TLSTTLADTR----------TPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLST 1994
Query: 1762 -------------LPVGTELPAGT-LPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPE 1807
PV T PA T P G + Q+ P E +S
Sbjct: 1995 TLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTT 2054
Query: 1808 MITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEG---PVLATSSGAGVFKMGRFQVSV 1864
++ V+S +S + T+ + S EG + A S G+ + +
Sbjct: 2055 LV-VSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTP 2113
Query: 1865 AADGAQKEGKNKSEDAKSVHFESSTSESSVL--SSSSPESTLVKPEPNGITIPGISSDVP 1922
A D+ S S+ SS + +S +++ +T +S+ V
Sbjct: 2114 VASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVV 2173
Query: 1923 ESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFM 1982
S+ +T S DT P VT + + S+ T T EG S PF
Sbjct: 2174 ASSAISTLSTTPVDTSTP-------VTNSTEARSSPTTSEGTSMPTSTPSEG---STPFT 2223
Query: 1983 DLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLP 2042
+ + +P V SE S L+ D S V + + SP S+P
Sbjct: 2224 SMPVSTMPVV--------TSEASTLSATPVD-----TSTPVTTSTEATSSPTTAEGTSIP 2270
Query: 2043 SQNLSQ 2048
+ LS+
Sbjct: 2271 TSTLSE 2276
Score = 124 bits (311), Expect = 1e-27
Identities = 391/1894 (20%), Positives = 646/1894 (34%), Gaps = 197/1894 (10%)
Query: 599 SQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQH-QQLQYQQPSISVLSDGTVDS 657
S+T + AS+ PTA TS ST E P + S LS VD+
Sbjct: 1187 SKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDT 1246
Query: 658 GQGSSVFTESRVSSQQTVSYGSQHEQAHST--GTVPGHIPSTVQAQSQPHG----VYPPS 711
+ V T + SS T + G+ + ++ T+ IP + + P P
Sbjct: 1247 S--TPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVD 1304
Query: 712 SVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQT-VQYSLSQTSTSSEATT 770
+ + + SSS +S P + + + P T V S +++
Sbjct: 1305 TKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDN 1364
Query: 771 AQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQP 830
+ PV+ P S G +P S P IPV+T P V S PV
Sbjct: 1365 STPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTS 1424
Query: 831 LPTPLLPQYPVS-------QIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTA 883
P + S IP STP S +T S+P++ TL+++ +
Sbjct: 1425 TPGTTSAEATSSPTTAEGISIPTSTP--SEGKTPLKSIPVSNTPVANSEASTLSTTPVDS 1482
Query: 884 AIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLY 943
P V++ S PT + + S P A+ S+ + ++E+ S
Sbjct: 1483 NSPVVTSTAVSSSPTPAEGTSIAIST--PSEGSTALTSIPVSTTTVASSEINSLSTTPAV 1540
Query: 944 QGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNL 1003
P Q A +++ + ST P L T++ E+N
Sbjct: 1541 TSTPVTTYSQASSSPTTADGTSMQT----STYSEGSTPLTSLPVS----TMLVVSSEANT 1592
Query: 1004 LVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTT 1063
L + + QV+ + + S + ++G S + + PV+ + + +T
Sbjct: 1593 LSTTP-IDSKTQVTASTEASSSTTAEGSSMTISTPSEG-SPLLTSIPVSTTPVASPEAST 1650
Query: 1064 LASSVDSAHSDVASGMSDGNENVPS------SSGRHEGRTTKRHYRKSVRSRSRHEKTSR 1117
L+++ ++S V + + P+ +S EGRT S+ R+ +S
Sbjct: 1651 LSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLT----SITVRTTPVASSA 1706
Query: 1118 -PKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERES 1176
L V N V E + + + P E T + + + +
Sbjct: 1707 ISTLSTTPVDNSTP--VTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTS----IPVSTTP 1760
Query: 1177 FVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIP---- 1232
+ + S V+ E + +G + S+ + P+
Sbjct: 1761 VLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLV 1820
Query: 1233 ASSMPQQIGI-PTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPG 1291
A+S + P S + VV S SP P + PSE T S S
Sbjct: 1821 ANSEASTLSTTPVDSNSPVVTSTA--VSSSPTPAEGTSIATSTPSE-GSTALTSIPVSTT 1877
Query: 1292 MNLSHSASSLSLQQAFSEL---RRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPT 1348
S ++LS A + AQ++ P TA + T PP L+SI V T
Sbjct: 1878 TVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPP-LTSIP-VST 1935
Query: 1349 TAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP--PVSES 1406
T A++ + S+ D T V + G + T + G P+ P+S +
Sbjct: 1936 TTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTT 1995
Query: 1407 PVLSSVVSSI-------TIPAVVSIS-----TTSPSLQVPTSTSEIVVSSTALYPSVTVS 1454
V+SS S++ + PA S TT+ + TST + A P T
Sbjct: 1996 LVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTL 2055
Query: 1455 ATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTS 1514
S+ + TP V + A S+ AT S T S PS S L + ST+
Sbjct: 2056 VVSSEGNTLSTTPVDSKTQVTNSTEASSS---ATAEGSSMTISAPSEGSPLLTSIPLSTT 2112
Query: 1515 TPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPS 1574
E +S +D S T+ S P+ +S S P P V +
Sbjct: 2113 PVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMP-VSTT 2171
Query: 1575 VIASTPILPQAAGP--TSTPLLPQVPS-IPPLVQPVANVPAVQQTLIHSQPQPALLP--N 1629
V+AS+ I + P TSTP+ + P ++P S P P +
Sbjct: 2172 VVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT-------STPSEGSTPFTS 2224
Query: 1630 QPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVT 1689
P + P V S+ + D T + +E +SS S+ TS + E T T
Sbjct: 2225 MPVSTMPVVTSEASTLSATPVDTSTPV----TTSTEATSSPTTAEGTSIPTSTLSEGT-T 2279
Query: 1690 P--GIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKP 1747
P IP + + ST ST +N P T +P T S P ST++ G
Sbjct: 2280 PLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEG--- 2336
Query: 1748 GTAPSKPPLTKAPV---------------------LPVGTELPAGTLP-SEQLPPFPGPS 1785
PLT+ PV PV T AG+ P + P +
Sbjct: 2337 -----NTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTST 2391
Query: 1786 LTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAP-TAITEAGTQ------------ 1832
++ PL + +S E T + PV + P T TEA +
Sbjct: 2392 YSEGSTPLTSVPVSTMPVVSSE--ASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTS 2449
Query: 1833 -PQKGVSQVKEGPVLAT---SSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESS 1888
P +G + + PV T SS AG S + + + + V S+
Sbjct: 2450 PPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIST 2509
Query: 1889 TSESSVLSSSSPEST--LVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRF 1946
SE S L +S P ST + PE + ++ + S+ P +S A S G +
Sbjct: 2510 ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTY 2569
Query: 1947 QVTTTANKVGRFSVSKTEDKITDTKKEGPV--ASPPFMDLEQAVLPAVIPKKEKPELSEP 2004
+T + S T PV + P E + P P +S P
Sbjct: 2570 SEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMP-ISTP 2628
Query: 2005 SHLNG----------PSSDPEAAFLSRD-------VDDGSGSPHSPHQLSSKSLPSQ--- 2044
S ++ P + EA+ LS V +G+ SP S+P+
Sbjct: 2629 SEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPG 2688
Query: 2045 NLSQSLSNSFNSSYMSSDNE-SDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYT 2103
S L+N S+ + +++E S + + I +
Sbjct: 2689 ERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIST--P 2746
Query: 2104 KLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLS--GNLSGQSAASVL 2161
G P I+ P++ SS +S++ + S S ++++S
Sbjct: 2747 SDGSTPLTSILVSTLPVA-------------SSEASTVSTTAVDTSIPVTTSTEASSSPT 2793
Query: 2162 HPQQTLHPPGNIPESGQNQLLQPLKPSP-SSDNLYSAFTSDGAISVPSLSAPGQGTSSTN 2220
+ T P E+ P+ +P +S + T+ S P ++ +S T
Sbjct: 2794 TAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTT 2853
Query: 2221 TVGATVNSQAAQAQPPAMTS---SRKGTFTDDLHKLVDNWARDAMNL-SGRRGSKGHMNY 2276
G V A +TS S + + L ++ + + GS
Sbjct: 2854 AEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTA 2913
Query: 2277 EGPGMARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQ 2336
EG M S P ++ +TS L + P++ + A++L P A+
Sbjct: 2914 EGTSM--PISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTT 2971
Query: 2337 WSGTGGPAPQPLGQFQPVGTASLQNFNISNLQKS 2370
GT P P + P+ + S+ +++ + S
Sbjct: 2972 AEGTSMPISTPGERRTPLTSMSVSTMPVASSEAS 3005
Score = 122 bits (307), Expect = 3e-27
Identities = 275/1391 (19%), Positives = 486/1391 (34%), Gaps = 150/1391 (10%)
Query: 593 VEQSSASQTGIKQLPSASTGIPTASTTSASVSTQ-VEPEEPEADQHQQLQYQQPSISVLS 651
+ +S T + +P ++T P AS+ ++++ST V+ P S S
Sbjct: 2861 ISTASEGSTLLTSIPVSTT--PVASSEASTLSTTPVDTSIPVTT----------STEGSS 2908
Query: 652 DGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPS 711
T G + T S VS+ T ST V G ST+ P
Sbjct: 2909 SPTTAEGTSMPISTPSEVSTPLT-------SILVSTVPVAGSEASTLSTT-------PVD 2954
Query: 712 SVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSE--AT 769
+ + + SSS T +S PI P +++ T+ T+ + S+ ST S A
Sbjct: 2955 TRTPVTTSAEASSSPTTAEGTSMPISTPGERR-TPLTSMSVSTMPVASSEASTLSRTPAD 3013
Query: 770 TAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQ 829
T+ PV+ P + G +P+S P IPV+T P +P S PV
Sbjct: 3014 TSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDS 3073
Query: 830 PLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVS 889
+P++ VS P TP T S+PI+ + + PL + S T +S
Sbjct: 3074 --NSPVVTSTEVSSSP--TPAEGT------SMPISTYSEGSTPLTGVPVSTTPVTSSAIS 3123
Query: 890 TVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPR 949
T+ + + T T + P + +P + PL+
Sbjct: 3124 TLSTTPVDTSTPVTTSTEAHSSP----TTSEGTSMPTSTPSEGSTPLT------------ 3167
Query: 950 LPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFP--TVVQPYVESNLLVPM 1007
P + + SS +++ S P+ T AT T + S + P+
Sbjct: 3168 ---YMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPL 3224
Query: 1008 GGVG-GQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLAS 1066
V V+ S+ S + ST+ S AE ++ + ++ +T +
Sbjct: 3225 TSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLT 3284
Query: 1067 SVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRP-------K 1119
S+ + + VAS + P+ + T Y ++ S + TS P
Sbjct: 3285 SMPVSTTTVASSETSTLSTTPADTS-----TPVTTYSQASSSPPIADGTSMPTSTYSEGS 3339
Query: 1120 LRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVD 1179
+ N+S VV + T + V + ++ I
Sbjct: 3340 TPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTT 3399
Query: 1180 QVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQ 1239
+ + ++S +V+ +L S EG S
Sbjct: 3400 PLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTP 3459
Query: 1240 IGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSAS 1299
+ I S T V S +PV DT T SP + +A
Sbjct: 3460 LSIMPLSTTPVASSEASTLSTTPV----------------DTSTPVTTSSPTNSSPTTAE 3503
Query: 1300 SLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVP----PFLSSIAGVPTTAAATAP 1355
S+ + + +T P + P S T P F++S + ++ A
Sbjct: 3504 VTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQV 3563
Query: 1356 VPATSSPPND----------ISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSE 1405
S P++ ST V SE + P+ + T S P PP
Sbjct: 3564 TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVI 3623
Query: 1406 SPVLSSVVSSITIPAVVSISTTSPSL-QVPTSTSEIVVSSTALYPSVTVSATSASAGGST 1464
+ +S+ T ++ +STTS ++ + T+++ V +ST + S VS++ + G+T
Sbjct: 3624 TLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTT 3683
Query: 1465 A---TPGPKPPAVVSQQAAG---STTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTL 1518
TP + + + +++ G+TL++ S TS P T S +I S++ + T+
Sbjct: 3684 MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTM 3743
Query: 1519 AETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIAS 1578
+ ++ + +L T STT + P SS+ V + +S P+ +
Sbjct: 3744 SVSMPMEISTLGTTILVSTTPVT---RFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEG 3800
Query: 1579 TPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEV 1638
T +P + + LL V L+ P++ + + + + + P P T
Sbjct: 3801 TTTMPMSTTSERSTLLTTV-----LISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSF 3855
Query: 1639 DSDTQPKAPGIDDIKTLEEKLRSLF-SEHSSSGAQHASVSLETSLVIESTVTPGIPTTAV 1697
+ I L +L S + AS++ L +T TP T +
Sbjct: 3856 SIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTAST 3915
Query: 1698 APSKLLTSTTSTCLPPTNLPLGTVALPVTPV---------VTPGQVSTPVSTTTSGVKPG 1748
+ T+ + + + + P T+ +P TPV T G VSTPV T+T P
Sbjct: 3916 PTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPS 3975
Query: 1749 TAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEM 1808
T+ S + + T PA T + P +T S P T S
Sbjct: 3976 TSSSSTTTSFSTTKEFTT--PAMTTAA------PLTYVTMSTAPSTPRTTSRGCTTSAST 4027
Query: 1809 ITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADG 1868
++ TS P T T+P S+ + + + F
Sbjct: 4028 LSATS--------TPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSA 4079
Query: 1869 AQKEGKNKSEDAKSVHFESSTSESS---VLSSSSPESTLVKPEPNGI-TIPGISSDVPES 1924
+ ++ + + ST +S V +++ P +T +K P T+P ++ +
Sbjct: 4080 SSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDG 4139
Query: 1925 AHKTTASEAKS 1935
+ TAS K+
Sbjct: 4140 C-QNTASRCKN 4149
Score = 81.3 bits (199), Expect = 1e-14
Identities = 218/979 (22%), Positives = 344/979 (35%), Gaps = 203/979 (20%)
Query: 1385 GVATSTGVVTSGGLPIPP-----VSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSE 1439
G A +T T+ + P S +P ++S+ SS+T +S+T + +TSE
Sbjct: 62 GSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTP-GVSSTRMTPTESRTTSE 120
Query: 1440 IVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFP 1499
ST L+PS T +S + T P P ++ +T+ VST P
Sbjct: 121 STSDSTTLFPSSTEDTSSPTTPEGTDVPMSTP---------SEESISSTMAFVSTAP-LP 170
Query: 1500 STASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSS 1559
S + S+ STP T S+ T+ STT P S++S G
Sbjct: 171 SFEAYTSLTYKVDMSTPLTTSTQASSS----PTTPESTT-------IPKSTNSEG----- 214
Query: 1560 YISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPV-ANVPAVQQTLI 1618
STP+ + P ST + +I L PV + P
Sbjct: 215 ------------------STPL---TSMPASTMKVASSEAITLLTTPVEISTPVTISAQA 253
Query: 1619 HSQPQPALLP----------NQPHTHCP-----EVDSD-----TQPKAPGIDDIKTLEEK 1658
S P A P + P T P V S+ T P A I I + E
Sbjct: 254 SSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEAS 313
Query: 1659 LRSLFSEHSS-----------------------SGAQHASVSL----ETSLVIESTVTPG 1691
+E +S + ++ +++S+ ++LV ST
Sbjct: 314 SSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSS 373
Query: 1692 IPTTAVAPSKLLTSTTSTCLPPTNLPLGTV-----------ALPV---TPVVTPGQVSTP 1737
+PTTA A S L ++ + P TN+P+ T+ +PV T V T + S+
Sbjct: 374 LPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSS 433
Query: 1738 VSTTTSGVKPGTAPSK--PPLTKAPV---------------LPVGTELPAGTL------- 1773
+T + PS+ PLT PV PV ++ T
Sbjct: 434 PTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSP 493
Query: 1774 PSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAP-TAITEAGTQ 1832
P+ ++ P + ++ PL + S E T+++ PV + P T +EA +
Sbjct: 494 PTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTT--PVDTSTPVTTSSEASSS 551
Query: 1833 PQKGVSQVKEGPVLATSS-GAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSE 1891
S EG + TS+ G + VS + + + A S F +++SE
Sbjct: 552 -----STTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSE 606
Query: 1892 SSVLS-----SSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRF 1946
+S S +S P ST IT +S+ + S+ +T S D+ P
Sbjct: 607 ASSSSTTAEGTSMPTST-YSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTP------ 659
Query: 1947 QVTTTANKVGRFSVSKTEDKITDTKKEG--PVASPPFMDLEQAVLPAVIPKKEKPELS-E 2003
VTT+ + ++ T T EG P+ S P V ++ E LS
Sbjct: 660 -VTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMP-------VNTTLVASSEASTLSTT 711
Query: 2004 PSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDN 2063
P + P + A S DG+ P S S L S +S++L S +S +S+
Sbjct: 712 PVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP 771
Query: 2064 ESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGR 2123
+ E + E L T + V P A+ LS
Sbjct: 772 LD--TSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTT 829
Query: 2124 --------------RRRPTKSKGSKSSRSSSLGNKSP----QLSGNLSGQSAASVLH--P 2163
PT ++G+ S+ ++P +S L SA S L P
Sbjct: 830 PVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTP 889
Query: 2164 QQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTS-DGAISVPSLSAPGQGTSSTNTV 2222
T P N E+ + SP++ S TS G S P S P T ++
Sbjct: 890 VDTSTPVTNSTEA---------RSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSE 940
Query: 2223 GATVNSQAAQAQPPAMTSS 2241
T+++ P TS+
Sbjct: 941 ARTLSATPVDTSTPVTTST 959
Score = 74.3 bits (181), Expect = 1e-12
Identities = 206/1006 (20%), Positives = 343/1006 (34%), Gaps = 136/1006 (13%)
Query: 597 SASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVD 656
S T + +P ++T P AS+ ++ +ST + P+ S T
Sbjct: 3218 SEGMTPLTSVPVSNT--PVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTST 3275
Query: 657 SGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQG 716
+GS+ T VS+ S + + T P + V SQ P +A G
Sbjct: 3276 PSEGSTPLTSMPVSTTTVAS-----SETSTLSTTPADTSTPVTTYSQASSSPP---IADG 3327
Query: 717 QSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQ 776
S P+S+ G S P+ + T P V S + T +++ T+ PV+
Sbjct: 3328 TSM--PTSTYSEG---STPLTNMSFS-----TTP----VVSSEASTLSTTPVDTSTPVTT 3373
Query: 777 PQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQP---------SVVPVHSG------ 821
+ P + G +P S P +PV+T P S PV S
Sbjct: 3374 STEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTS 3433
Query: 822 -----AHFLPVGQPLPTPLLPQ--YPVSQIPISTPHVSTAQTG-FSSLPITMAAGITQPL 873
+ + G LPT + P+S +P+ST V++++ S+ P+ + +T
Sbjct: 3434 TEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSS 3493
Query: 874 LTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPA--VQSMGIPANLGQA 931
T SS TTA + + T + T P+T +P P A + + + +N
Sbjct: 3494 PT-NSSPTTAEVTSMPTSTAGEGST---PLTNMPVSTTPVASSEASTLSTTPVDSNTFVT 3549
Query: 932 AEVPLSSGDVLYQGFPPRLPPQYPGDSNIAP---SSNVASVCIHSTVLSP---------- 978
+ SS Q R+ G S++ SS + ST +P
Sbjct: 3550 SSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTT 3609
Query: 979 -------PMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSS 1031
P P EV+ P P+ V S L M V +S+ G+ + P +S
Sbjct: 3610 STQSNSTPTPPEVITLPMSTPSEV-----STPLTIMPVSTTSVTISE-AGTASTLPVDTS 3663
Query: 1032 QQAVLESTQGVSQVAP---AEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGN--ENV 1086
+ + S V P P+ +T TT+ S S S +S + +
Sbjct: 3664 TPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTST 3723
Query: 1087 PSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVT 1146
P ++ E ++ + S S + S IL + R E + +
Sbjct: 3724 PVTTST-EAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTS 3782
Query: 1147 FKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSV--EPEGDQ 1204
+ T+ ++ E +I M + S P GD
Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDT 3842
Query: 1205 GLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVP 1264
L FS IPA +I I + T + + + P
Sbjct: 3843 STPLLTSTKAGSFS------------IPAEVTTIRISITSERSTPLTTLLVSTTLPTSFP 3890
Query: 1265 ESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPP 1324
+ + + + T T + TA +P + ++ + S + + T G P
Sbjct: 3891 GASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEG--------STPGTTIFIP 3942
Query: 1325 NFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIA 1384
+ T T V P TT A + PV TS+ N STS + + T +
Sbjct: 3943 STPVTSSTADVFPA---------TTGAVSTPV-ITSTELNTPSTSSSSTTTSFSTTKEFT 3992
Query: 1385 GVATSTGV----VTSGGLPIPPVSES---PVLSSVVSSITIPAVVSISTTSPSLQVPTST 1437
A +T VT P P + S +S +S+ + P + TT P S+
Sbjct: 3993 TPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESS 4052
Query: 1438 SEIVVSSTALYPSVTVSATSA----SAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVS 1493
++S + P+ + +S SA +T P AV + + T
Sbjct: 4053 RPSTITSHTIPPTFPPAHSSTPPTTSASSTTV----NPEAVTTMTTRTKPSTRTTSFPTV 4108
Query: 1494 TTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTG 1539
TTT+ P+ + S+ TSTPT+ T T+ G
Sbjct: 4109 TTTAVPTNTT----IKSNPTSTPTVPRTTTCFGDGCQNTASRCKNG 4150
>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
Length = 841
Score = 127 bits (318), Expect = 2e-28
Identities = 82/267 (30%), Positives = 139/267 (52%), Gaps = 13/267 (4%)
Query: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDS 286
+G+GS+ V + +L R + ER+ ++EA++L L+HPNIV + +S
Sbjct: 12 VGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKES 71
Query: 287 WESTVKGKKCIVLVTELMTSGTLKTYLKRFK--VMKIKVLRSWCRQILKGLQFLHTRTPP 344
WE G + +V G L LK K ++ + W QI LQ+LH +
Sbjct: 72 WEG---GDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEK--H 126
Query: 345 IIHRDLKCDNIFITGPTGSVKIGDLGLATL--KRASFAKSVIGTPEFMAPEMYEEK-YDE 401
I+HRDLK N+F+T T +K+GDLG+A + A ++IGTP +M+PE++ K Y+
Sbjct: 127 ILHRDLKTQNVFLT-RTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNY 185
Query: 402 SVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIR 461
DV+A G C+ EMAT ++ ++ + +YR + + P D PE+ E+I +
Sbjct: 186 KSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRD--YSPELAELIRTMLS 243
Query: 462 QNKDERYSIKDLLNHAFFQEETGVRVE 488
+ +ER S++ +L + + + +E
Sbjct: 244 KRPEERPSVRSILRQPYIKRQISFFLE 270
>gi|189491759 p21-activated kinase 3 isoform d [Homo sapiens]
Length = 559
Score = 124 bits (310), Expect = 1e-27
Identities = 103/385 (26%), Positives = 176/385 (45%), Gaps = 26/385 (6%)
Query: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSK 162
P + A+ P APP E+ + +PP AP + +V S
Sbjct: 170 PSSTKTASEPPLAPPVSEEEDEEEEEEEDE--NEPPPVIAPRPEHTKSIYTRSVVES--- 224
Query: 163 DRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDG---- 218
++ P++ + PP A + + + +R + + EE+ K + + G
Sbjct: 225 ---IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKK 281
Query: 219 RFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP 278
++ +F+ +IG+G+ TVY LD T EVA ++ ++ K E E +++ ++P
Sbjct: 282 KYTRFE-KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNP 338
Query: 279 NIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFL 338
NIV + DS+ + G + V V E + G+L + M + + CR+ L+ L FL
Sbjct: 339 NIVNYLDSY---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALDFL 393
Query: 339 HTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYE 396
H+ +IHRD+K DNI + G GSVK+ D G S +++GTP +MAPE+
Sbjct: 394 HSNQ--VIHRDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT 450
Query: 397 EK-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEI 455
K Y VD+++ G+ +EM E PY +Y T+G + ++
Sbjct: 451 RKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDF 510
Query: 456 IEGCIRQNKDERYSIKDLLNHAFFQ 480
+ C+ + D R S K+LL H F +
Sbjct: 511 LNRCLEMDVDRRGSAKELLQHPFLK 535
>gi|189491757 p21-activated kinase 3 isoform c [Homo sapiens]
Length = 565
Score = 124 bits (310), Expect = 1e-27
Identities = 103/385 (26%), Positives = 176/385 (45%), Gaps = 26/385 (6%)
Query: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSK 162
P + A+ P APP E+ + +PP AP + +V S
Sbjct: 176 PSSTKTASEPPLAPPVSEEEDEEEEEEEDE--NEPPPVIAPRPEHTKSIYTRSVVES--- 230
Query: 163 DRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDG---- 218
++ P++ + PP A + + + +R + + EE+ K + + G
Sbjct: 231 ---IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKK 287
Query: 219 RFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP 278
++ +F+ +IG+G+ TVY LD T EVA ++ ++ K E E +++ ++P
Sbjct: 288 KYTRFE-KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNP 344
Query: 279 NIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFL 338
NIV + DS+ + G + V V E + G+L + M + + CR+ L+ L FL
Sbjct: 345 NIVNYLDSY---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALDFL 399
Query: 339 HTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYE 396
H+ +IHRD+K DNI + G GSVK+ D G S +++GTP +MAPE+
Sbjct: 400 HSNQ--VIHRDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT 456
Query: 397 EK-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEI 455
K Y VD+++ G+ +EM E PY +Y T+G + ++
Sbjct: 457 RKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDF 516
Query: 456 IEGCIRQNKDERYSIKDLLNHAFFQ 480
+ C+ + D R S K+LL H F +
Sbjct: 517 LNRCLEMDVDRRGSAKELLQHPFLK 541
>gi|189491755 p21-activated kinase 3 isoform b [Homo sapiens]
Length = 580
Score = 124 bits (310), Expect = 1e-27
Identities = 103/385 (26%), Positives = 176/385 (45%), Gaps = 26/385 (6%)
Query: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSK 162
P + A+ P APP E+ + +PP AP + +V S
Sbjct: 191 PSSTKTASEPPLAPPVSEEEDEEEEEEEDE--NEPPPVIAPRPEHTKSIYTRSVVES--- 245
Query: 163 DRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDG---- 218
++ P++ + PP A + + + +R + + EE+ K + + G
Sbjct: 246 ---IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKK 302
Query: 219 RFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP 278
++ +F+ +IG+G+ TVY LD T EVA ++ ++ K E E +++ ++P
Sbjct: 303 KYTRFE-KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNP 359
Query: 279 NIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFL 338
NIV + DS+ + G + V V E + G+L + M + + CR+ L+ L FL
Sbjct: 360 NIVNYLDSY---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALDFL 414
Query: 339 HTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYE 396
H+ +IHRD+K DNI + G GSVK+ D G S +++GTP +MAPE+
Sbjct: 415 HSNQ--VIHRDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT 471
Query: 397 EK-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEI 455
K Y VD+++ G+ +EM E PY +Y T+G + ++
Sbjct: 472 RKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDF 531
Query: 456 IEGCIRQNKDERYSIKDLLNHAFFQ 480
+ C+ + D R S K+LL H F +
Sbjct: 532 LNRCLEMDVDRRGSAKELLQHPFLK 556
>gi|189491753 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 124 bits (310), Expect = 1e-27
Identities = 103/385 (26%), Positives = 176/385 (45%), Gaps = 26/385 (6%)
Query: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSK 162
P + A+ P APP E+ + +PP AP + +V S
Sbjct: 155 PSSTKTASEPPLAPPVSEEEDEEEEEEEDE--NEPPPVIAPRPEHTKSIYTRSVVES--- 209
Query: 163 DRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDG---- 218
++ P++ + PP A + + + +R + + EE+ K + + G
Sbjct: 210 ---IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKK 266
Query: 219 RFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP 278
++ +F+ +IG+G+ TVY LD T EVA ++ ++ K E E +++ ++P
Sbjct: 267 KYTRFE-KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNP 323
Query: 279 NIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFL 338
NIV + DS+ + G + V V E + G+L + M + + CR+ L+ L FL
Sbjct: 324 NIVNYLDSY---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALDFL 378
Query: 339 HTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYE 396
H+ +IHRD+K DNI + G GSVK+ D G S +++GTP +MAPE+
Sbjct: 379 HSNQ--VIHRDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT 435
Query: 397 EK-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEI 455
K Y VD+++ G+ +EM E PY +Y T+G + ++
Sbjct: 436 RKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDF 495
Query: 456 IEGCIRQNKDERYSIKDLLNHAFFQ 480
+ C+ + D R S K+LL H F +
Sbjct: 496 LNRCLEMDVDRRGSAKELLQHPFLK 520
>gi|189491751 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 124 bits (310), Expect = 1e-27
Identities = 103/385 (26%), Positives = 176/385 (45%), Gaps = 26/385 (6%)
Query: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSK 162
P + A+ P APP E+ + +PP AP + +V S
Sbjct: 155 PSSTKTASEPPLAPPVSEEEDEEEEEEEDE--NEPPPVIAPRPEHTKSIYTRSVVES--- 209
Query: 163 DRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDG---- 218
++ P++ + PP A + + + +R + + EE+ K + + G
Sbjct: 210 ---IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKK 266
Query: 219 RFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP 278
++ +F+ +IG+G+ TVY LD T EVA ++ ++ K E E +++ ++P
Sbjct: 267 KYTRFE-KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNP 323
Query: 279 NIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFL 338
NIV + DS+ + G + V V E + G+L + M + + CR+ L+ L FL
Sbjct: 324 NIVNYLDSY---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALDFL 378
Query: 339 HTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYE 396
H+ +IHRD+K DNI + G GSVK+ D G S +++GTP +MAPE+
Sbjct: 379 HSNQ--VIHRDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT 435
Query: 397 EK-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEI 455
K Y VD+++ G+ +EM E PY +Y T+G + ++
Sbjct: 436 RKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDF 495
Query: 456 IEGCIRQNKDERYSIKDLLNHAFFQ 480
+ C+ + D R S K+LL H F +
Sbjct: 496 LNRCLEMDVDRRGSAKELLQHPFLK 520
>gi|4505601 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 124 bits (310), Expect = 1e-27
Identities = 103/385 (26%), Positives = 176/385 (45%), Gaps = 26/385 (6%)
Query: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSK 162
P + A+ P APP E+ + +PP AP + +V S
Sbjct: 155 PSSTKTASEPPLAPPVSEEEDEEEEEEEDE--NEPPPVIAPRPEHTKSIYTRSVVES--- 209
Query: 163 DRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDG---- 218
++ P++ + PP A + + + +R + + EE+ K + + G
Sbjct: 210 ---IASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKK 266
Query: 219 RFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP 278
++ +F+ +IG+G+ TVY LD T EVA ++ ++ K E E +++ ++P
Sbjct: 267 KYTRFE-KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNP 323
Query: 279 NIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFL 338
NIV + DS+ + G + V V E + G+L + M + + CR+ L+ L FL
Sbjct: 324 NIVNYLDSY---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALDFL 378
Query: 339 HTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYE 396
H+ +IHRD+K DNI + G GSVK+ D G S +++GTP +MAPE+
Sbjct: 379 HSNQ--VIHRDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT 435
Query: 397 EK-YDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEI 455
K Y VD+++ G+ +EM E PY +Y T+G + ++
Sbjct: 436 RKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDF 495
Query: 456 IEGCIRQNKDERYSIKDLLNHAFFQ 480
+ C+ + D R S K+LL H F +
Sbjct: 496 LNRCLEMDVDRRGSAKELLQHPFLK 520
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 122 bits (305), Expect = 5e-27
Identities = 381/1811 (21%), Positives = 650/1811 (35%), Gaps = 327/1811 (18%)
Query: 580 EKKKQEESSLKQQVEQS-SASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQ 638
EK S L V S S S T + +PS+S + T+ T V T EP
Sbjct: 10016 EKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSV-TSLLTPGMVKTTDTSTEPGTSLSP 10074
Query: 639 QLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTV 698
L I S+ T D+ + S ++ + S HE + S+V
Sbjct: 10075 NLSGTSVEILAASEVTTDT---EKIHPSSSMAVTNVGTTSSGHE-----------LYSSV 10120
Query: 699 QAQSQPH-GVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQY 757
S+P YP G PSS + T +S+S P + G + A P +
Sbjct: 10121 SIHSEPSKATYPV---------GTPSSMAETSISTSMPANF--ETTGFE--AEPFSHLTS 10167
Query: 758 SLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVP 817
+T+ S + ++ P + P +P + + K S + P P A+Q + +P
Sbjct: 10168 GFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTS---SPDWPPASQYTEIP 10224
Query: 818 VHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLA 877
V + TP ++P + T TG +S P + T +
Sbjct: 10225 VD-----------IITPFN----------ASPSI-TESTGITSFP---ESRFTMSVTEST 10259
Query: 878 SSATTAAIPGVSTV-VPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPL 936
+T +P T+ + +P+L + +T + P+ A+ G P + ++
Sbjct: 10260 HHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPR----AISGSGSPFSRTESGP--- 10312
Query: 937 SSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQ 996
GD LP P + SS+ + ST+ + T AT
Sbjct: 10313 --GDATLSTIAESLPSSTP----VPFSSSTFTTTDSSTIPALHEITSSSAT--------- 10357
Query: 997 PY-VESNLLVPMGGVGGQ-VQVSQPGGSLAQAPTTSSQQAVLESTQGVS--QVAPAEPVA 1052
PY V+++L G+ V VS S T+SS T+ V V A V
Sbjct: 10358 PYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVP 10417
Query: 1053 VAQTQATQPTTLASSV-----DSAHSDVASGMSDGNENVPSSS--GRHEGRTTK------ 1099
T+ T+ + + ++AH + + +S G H G T +
Sbjct: 10418 SLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTT 10477
Query: 1100 --RHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPE 1157
+ ++++ SR T+ L + ++ M+T + D PE
Sbjct: 10478 ALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFP-DVPE 10536
Query: 1158 EIATIMVNNDFILAIERESFVDQVREII-----EKADEMLSEDVSVEPEGDQGLESLQGK 1212
+++ + L E + + + + E ++S + Q L+ +
Sbjct: 10537 TTSSLATS----LGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSE 10592
Query: 1213 DDYGFSGSQKLEGEFKQPIPASSMPQ--QIGIPTSSLTQVVHSAGRRFIVSPVPESRLRE 1270
D + S + P + + P + T S T H A + S +P
Sbjct: 10593 PDT--TASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGAD---VSSAIP------ 10641
Query: 1271 SKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMT---EGPNTAP---P 1324
+ + PSE+ T G + S + +L+ +E R +T E +T P P
Sbjct: 10642 TNISPSELDALTPLVTIS--GTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIP 10699
Query: 1325 NFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSE-----VTVPT 1379
NFSH P +++ G T++A P+ S D+ TS + S +T+PT
Sbjct: 10700 NFSHHESD---ATPSIATSPGAETSSAI--PIMTVSPGAEDLVTSQVTSSGTDRNMTIPT 10754
Query: 1380 -------EEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQ 1432
+ IA + T TS +P +S P +S +V+S+ STT+ +L
Sbjct: 10755 LTLSPGEPKTIASLVTHPEAQTSSAIPTSTIS--PAVSRLVTSMVTSLAAKTSTTNRALT 10812
Query: 1433 ----------------------VPTSTSEIVVSSTALYPSVTVSATSASAGG------ST 1464
VP +TS S + PS+T S + S+ ST
Sbjct: 10813 NSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVST 10872
Query: 1465 ATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVV 1524
PG P V S +A STT+ S + PS A+ + SS+ TPT++ V
Sbjct: 10873 EVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPG 10932
Query: 1525 SAHSLDKTSHSSTTG----LAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSV---IA 1577
SL +S + T+ L FSL P ++ S +S+ ++ G P V+P V +
Sbjct: 10933 VVTSLVTSSRAVTSTTIPILTFSLGEPETTPSM---ATSHGTEAGSAVPTVLPEVPGMVT 10989
Query: 1578 STPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPE 1637
S +A T+ P L P P +A + S P + P P
Sbjct: 10990 SLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEA----SSTVPTVSPEVPGVVTSL 11045
Query: 1638 VDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIP---T 1694
V S + + I + +L + S +S GA+ +S V TV+PG+ T
Sbjct: 11046 VTSSSGVNSTSIPTLILSPGELETTPSMATSHGAE------ASSAVPTPTVSPGVSGVVT 11099
Query: 1695 TAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKP 1754
V S+ +TSTT +P+ + + +TP T+ GV+ +A
Sbjct: 11100 PLVTSSRAVTSTT---------------IPILTLSSSEPETTPSMATSHGVEASSA---- 11140
Query: 1755 PLTKAPVLP-------------VGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLR 1801
LT +P +P T +P T+ S++ P +T S+ + + A
Sbjct: 11141 VLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDE-PETTTSLVTHSEAKM--ISAIPT 11197
Query: 1802 RTLSPEMITVTSAVGPVSMAAPTA---ITEAGTQPQ--------KGVSQVKEGPVLATSS 1850
+SP + + +++ S + +A +T A +QP+ G P L S+
Sbjct: 11198 LAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVST 11257
Query: 1851 GAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLS----SSSPESTLVK 1906
G +S+ A+ ++ H E T S+V S SSS ST +
Sbjct: 11258 GEPF-----TNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTIS 11312
Query: 1907 PEPNGITIPGISSD----------VPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVG 1956
P G+ ++S VPES H++ A+ + T TT
Sbjct: 11313 PGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTS------TTVPRTTP 11366
Query: 1957 RFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEA 2016
+S S+ + + G A+ F P + + P++ SS +
Sbjct: 11367 NYSHSEPDTTPSIATSPGAEATSDF--------PTITVSPDVPDMVTS---QVTSSGTDT 11415
Query: 2017 AFLSRDVDDGSGSPHSPHQL-------SSKSLPSQNLSQSLSNSFNSSYMSSDNES---- 2065
+ + SG P + +S ++P+ +S S S +SS +S
Sbjct: 11416 SITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTF 11475
Query: 2066 -DIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRR 2124
+ + + E ++ H E + R + ++K P I P
Sbjct: 11476 PTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFS--HSKSDTTLPVAITSP-------- 11525
Query: 2125 RRPTKSKGSKSSRSSSLGNKSPQLSG---NLSGQSAASVLHPQQTLHPPGNIPESGQNQL 2181
G ++S + S SP +S +L S TL PE+ L
Sbjct: 11526 -------GPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWL 11578
Query: 2182 LQPLKPSPSSDNLYSAFTSDGAISVPSL-SAPGQGTSS---TNTVGATVNSQAAQAQPPA 2237
P + S + F+ G+ + PS+ ++PG T S T T+ ++ P
Sbjct: 11579 THPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSI--------PGV 11630
Query: 2238 MTSSRKGTFTD 2248
+TS + TD
Sbjct: 11631 VTSQVTSSATD 11641
Score = 118 bits (296), Expect = 6e-26
Identities = 343/1601 (21%), Positives = 566/1601 (35%), Gaps = 235/1601 (14%)
Query: 563 SLIKRKREQRQLVREEQEKKKQE-ESSLKQQVEQSSASQTGIKQLPSA-STGIPTASTTS 620
SL+ R +R V + + E +++ + + T K P+ + + T S+T+
Sbjct: 10570 SLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTA 10629
Query: 621 ASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQ 680
S V P +L P +++ GT D+ T+S ++ ++ +
Sbjct: 10630 TSHGADVSSAIPTNISPSELDALTPLVTI--SGT-DTSTTFPTLTKSPHETETRTTWLTH 10686
Query: 681 HEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQ 740
A ++ T+P IP+ + +S PS ++ G +S I
Sbjct: 10687 --PAETSSTIPRTIPN----------------FSHHESDATPSIATSPGAETSSAIPIMT 10728
Query: 741 QQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPT 800
G + Q T + T T P P+ + + + S +PT
Sbjct: 10729 VSPGAEDLVTSQVT------SSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPT 10782
Query: 801 IQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQT--GF 858
P + V + A + L P P + + + T T+ T
Sbjct: 10783 STISPAVSRLVTSMVTSL--AAKTSTTNRALTNS--PGEPATTVSLVTHPAQTSPTVPWT 10838
Query: 859 SSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPA 918
+S+ + T + T + +++A+P + V +++P ++ P+ V +
Sbjct: 10839 TSIFFHSKSDTTPSMTTSHGAESSSAVP--TPTVSTEVPGVVTPLVTSSRAVISTTIPIL 10896
Query: 919 VQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSP 978
S G P A S G+ P P PG + S +S + ST +
Sbjct: 10897 TLSPGEPETTPSMAT---SHGEEASSAIPT--PTVSPGVPGVVTSLVTSSRAVTSTTI-- 10949
Query: 979 PMPTEVLATPGYFPTVVQPY-VESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLE 1037
P+ T L P P++ + E+ VP V PG +S +AV
Sbjct: 10950 PILTFSLGEPETTPSMATSHGTEAGSAVPT------VLPEVPG---MVTSLVASSRAVTS 11000
Query: 1038 STQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRT 1097
+T ++P EP ++ S S ++ + VP+ S G
Sbjct: 11001 TTLPTLTLSPGEP------------------ETTPSMATSHGAEASSTVPTVSPEVPGVV 11042
Query: 1098 TKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPE 1157
T V S S TS P L + + G+ LET + + P
Sbjct: 11043 TSL-----VTSSSGVNSTSIPTL----ILSPGE------LETTPSMATSHGAEASSAVPT 11087
Query: 1158 EIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYG- 1216
+ V+ V R + +L+ S EPE + + G +
Sbjct: 11088 PTVSPGVSGVVT------PLVTSSRAVTSTTIPILTLSSS-EPETTPSMATSHGVEASSA 11140
Query: 1217 -FSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFP 1275
+ S ++ G + +S IPT +++ S S V S + P
Sbjct: 11141 VLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTIS----SDEPETTTSLVTHSEAKMISAIP 11196
Query: 1276 SEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPV 1335
T+A S G+ S SS S AFS L A + P T +H G
Sbjct: 11197 -----TLAVSPTVQ-GLVTSLVTSSGSETSAFSNLTVA--SSQPETIDSWVAHPGTEASS 11248
Query: 1336 VPPFLSSIAGVPTT--------AAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVA 1387
V P L+ G P T A +++ +P T+S + + S VT P E + ++
Sbjct: 11249 VVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAIS 11308
Query: 1388 TS---------TGVVTSGGLPI----PPVSESPVLSSVVSS-ITIPAVVS--ISTTSP-- 1429
T+ T +VTS G I P V ESP S +S +T PAV S + T+P
Sbjct: 11309 TTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTVPRTTPNY 11368
Query: 1430 SLQVPTSTSEIVVS----STALYPSVTVS------ATSASAGGSTATPGPKPPAVVSQQA 1479
S P +T I S +T+ +P++TVS TS T T P +S
Sbjct: 11369 SHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGE 11428
Query: 1480 AGSTTVGATLTSVSTTTSFPS-----------TASQLSIQLSSSTSTPTLAETVVVSAHS 1528
+TT T + T+++ P+ T+ +S S+T+ PTL ET +
Sbjct: 11429 PETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETT 11488
Query: 1529 LDKTSHSSTTGLAFSLSAPS-SSSSPGAGVSSYISQPGGLHPLVIPSVIAS-------TP 1580
+ H + T + P S S + I+ PG + + S T
Sbjct: 11489 AIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTS 11548
Query: 1581 ILPQAAGPTST--PLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEV 1638
++P + TST P L + P P PA T + +PN H
Sbjct: 11549 LVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGT-----IPNFSHR----- 11598
Query: 1639 DSDTQPK---APGIDD-----IKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTP 1690
SDT P +PG+D T+ + + + +S A S ++ T T +P
Sbjct: 11599 GSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTL-----TPSP 11653
Query: 1691 GIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTA 1750
G P T + + + T +P +P + V P Q STPVS TTS +
Sbjct: 11654 GEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSP 11713
Query: 1751 PSKPPLTKAP-----------VLPVGTELPAGTLPSE-QLPPFPGPSLTQSQQPLEDLDA 1798
+ P + +P + P E+ + S P+LT S E
Sbjct: 11714 DATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPE---- 11769
Query: 1799 QLRRTLSPEMITVTSAVGPVSMAAP-TAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKM 1857
LS T TS P S P + T A + G P TSS +
Sbjct: 11770 -TTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVT 11828
Query: 1858 GRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGI 1917
G +V ++ + G + S H T S+++ +S+ L+ E G+
Sbjct: 11829 GTSRVDLSPTAS--PGVSAKTAPLSTH--PGTETSTMIPTSTLSLGLL--ETTGLLATSS 11882
Query: 1918 SSDVPESAHKTTASEAKS-------DTGQPTKVGRFQVTT--TANKVGRFSVSKTEDKIT 1968
S++ S T S A S T +P V + T + VG S+T T
Sbjct: 11883 SAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTT 11942
Query: 1969 DTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSG 2028
T + +PP + V P I + + E ++L S P A + + +G
Sbjct: 11943 MTLIPSEMPTPPKTSHGEGVSPTTI---LRTTMVEATNLATTGSSPTVAKTTTTFNTLAG 11999
Query: 2029 SPHSP------HQLSSKSLPSQNLSQ-----SLSNSFNSSY 2058
S +P L+S+S+ S+ S ++S+N Y
Sbjct: 12000 SLFTPLTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRY 12040
Score = 86.3 bits (212), Expect = 3e-16
Identities = 248/1185 (20%), Positives = 421/1185 (35%), Gaps = 220/1185 (18%)
Query: 666 ESRVSSQQTVSYGSQHEQAHSTGT--VPGHIPSTVQAQSQPHGVYPPSSV-AQGQSQGQP 722
E + S+G++ T + VPG + S V + S + P+ + + G+ + P
Sbjct: 11012 EPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTP 11071
Query: 723 SSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQT-------------------- 762
S ++ G +S + P G+ P T +++ T
Sbjct: 11072 SMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMAT 11131
Query: 763 STSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGA 822
S EA++A P+ P ++ + + S +PT+ P T V HS A
Sbjct: 11132 SHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVT--HSEA 11189
Query: 823 HFL---------PVGQPLPTPLLPQYPVSQIPISTPHVSTAQ------------TGFSSL 861
+ P Q L T L+ S V+++Q T SS+
Sbjct: 11190 KMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSV 11249
Query: 862 PITMAAGITQP-----LLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQ 916
T+ +P L+T + +++ S S+L T+ VT P +
Sbjct: 11250 VPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTS-PEAESSSAIS 11308
Query: 917 PAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVL 976
+ S GIP G + SSG + FP P+ P +S A +S V + ST +
Sbjct: 11309 TTI-SPGIP---GVLTSLVTSSGRDISATFPT--VPESPHESE-ATASWVTHPAVTSTTV 11361
Query: 977 ---------SPPMPTEVLAT-PGY-----FPTV-VQPYVESNLLVPMGGVGGQVQVSQPG 1020
S P T +AT PG FPT+ V P V + + G ++ P
Sbjct: 11362 PRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPT 11421
Query: 1021 GSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMS 1080
+L+ ++ + S S P PV+ ++ ++S +
Sbjct: 11422 LTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSG------------T 11469
Query: 1081 DGNENVPS-SSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLET 1139
D P+ + +E TT + + +T+ PK +
Sbjct: 11470 DSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTT-PKF------------------S 11510
Query: 1140 HNRKMVTFKFDLDGDNPEEIATIMVN------NDFILAIERESFVDQVREIIEKADEMLS 1193
H++ T + PE + + +D + ++ S D LS
Sbjct: 11511 HSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTF-----PTLS 11565
Query: 1194 EDVSVEPEGDQGLESLQGKDDYGFSG-----SQKLEGEFKQPIPASSMPQQIGIPTSSLT 1248
E EPE + + SG S + + + + + G+PT+++
Sbjct: 11566 E-TPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIP 11624
Query: 1249 QVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFS 1308
+ + S ++ + PS AS+A PG + ++ +
Sbjct: 11625 PSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEP 11684
Query: 1309 ELRRAQMTEGPNTAPP------NFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSP 1362
+ + +T P T+ P +FSH+ P PV ATS
Sbjct: 11685 DTMASWVTHPPQTSTPVSRTTSSFSHSSPD--------------------ATPVMATS-- 11722
Query: 1363 PNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVV 1422
P ++S + + ++ E + TS+G TS +P ++ SP + P
Sbjct: 11723 PRTEASSAVLTTISPGAPEMVTSQITSSGAATS--TTVPTLTHSPGM---------PETT 11771
Query: 1423 SISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGS 1482
++ +T P T TS+ +ST ++P V S T+AS T PG + + Q S
Sbjct: 11772 ALLSTHPR----TETSKTFPAST-VFPQV--SETTASL---TIRPGAETSTALPTQTTSS 11821
Query: 1483 T----TVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTT 1538
G + +S T S +A + T T T+ T +S L+ TT
Sbjct: 11822 LFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLE------TT 11875
Query: 1539 GL-AFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQV 1597
GL A S SA +S+S+ VS +S GL S + T PQ +T P V
Sbjct: 11876 GLLATSSSAETSTSTLTLTVSPAVS---GL------SSASITTDKPQTVTSWNTETSPSV 11926
Query: 1598 PSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEE 1657
S+ P + V TLI P+ +P P T E S T ++T
Sbjct: 11927 TSVGP-PEFSRTVTGTTMTLI-----PSEMPTPPKTSHGEGVSPTTI-------LRTTMV 11973
Query: 1658 KLRSLFSEHSSSGAQHASVSLET--SLVIESTVTPGIPTTAVAPSKLLTSTTS------- 1708
+ +L + SS + + T + TPG+ T A S+ +TS TS
Sbjct: 11974 EATNLATTGSSPTVAKTTTTFNTLAGSLFTPLTTPGMSTLA---SESVTSRTSYNHRSWI 12030
Query: 1709 TCLPPTNLPLGTVAL--PVTPVVTPGQVSTPVSTTTSGVKPGTAP 1751
+ N T A PVT +PG ++ + ++T+ P P
Sbjct: 12031 STTSSYNRRYWTPATSTPVTSTFSPGISTSSIPSSTAATVPFMVP 12075
Score = 85.9 bits (211), Expect = 4e-16
Identities = 391/1948 (20%), Positives = 687/1948 (35%), Gaps = 401/1948 (20%)
Query: 599 SQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSD------ 652
SQ+ +++ SAS+ + +TTS S + E+ + P + + +D
Sbjct: 8256 SQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISR 8315
Query: 653 --GTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGT-----VPGH-IPSTVQAQSQP 704
GT + SS E + + TV H+ T + GH S+V + S+
Sbjct: 8316 EPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSET 8375
Query: 705 HGVYPP---------SSVAQGQS--------QGQPSSSSLTGV---SSSQPIQHPQQQQG 744
P +SV+ S Q +P+SS +G+ SSS+ I +
Sbjct: 8376 PKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGST 8435
Query: 745 IQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVS-QPVPTIQG 803
+ P T + S ++ SS T+ +S P + P +S +S P+ T
Sbjct: 8436 VLSEVPSGATTEVSRTEV-ISSRGTS---MSGPDQFTISPDISTEAITRLSTSPIMTESA 8491
Query: 804 EPQIPVAT-------------QPSVVPVHSGAHFLP---------------VGQPLPTPL 835
E I + T S SG H +P P
Sbjct: 8492 ESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPS 8551
Query: 836 LPQYPV---------SQIPISTPHVSTAQTGFSSLP------ITMAAGITQPLLTLASSA 880
LP S ST ST SS P +T+ T +L +S
Sbjct: 8552 LPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEP 8611
Query: 881 TTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQ----------SMGIPANLGQ 930
T++ P +S+ L T VT+ ++HP P V + A+L
Sbjct: 8612 ETSSPPNLSSTSAEILAT--SEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVT 8669
Query: 931 AAEV-PLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIH-STVLSPPMPTEVLATP 988
P+++ L P +P P+S++ S ST TE A+
Sbjct: 8670 TKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASL 8729
Query: 989 GYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPA 1048
PT V + +G + S PG + + S + + + ++ A
Sbjct: 8730 SGMPTGATTKVSRTEALSLG------RTSTPGPAQSTISPEISTETITRISTPLTTTGSA 8783
Query: 1049 EPVAVAQT-----------------QATQPTTLASSVD-SAHSDVASGMSDGNENV---- 1086
E +T +A+ P T +++ S HS + + MS G E+V
Sbjct: 8784 EMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPS 8843
Query: 1087 --------PSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLE 1138
P SS T S S S H R V K +++ LE
Sbjct: 8844 RPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLE 8903
Query: 1139 -----------THNRKMVTFKFDLDGDNPE--------EIATIMVNNDFILA---IERES 1176
T + + T K ++ + + ++ TI +F + + S
Sbjct: 8904 PVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPS 8963
Query: 1177 FVDQ-------VREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFK- 1228
V +++I+ SE +E E L + S SQ++ K
Sbjct: 8964 KVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPTPRET----STSQEIHSATKP 9019
Query: 1229 QPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPE-------------SRLRESKVFP 1275
+P ++ S+TQV+ S+ P P+ +RL S +
Sbjct: 9020 STVPYKALTS--ATIEDSMTQVMSSSR-----GPSPDQSTMSQDISTEVITRLSTSPI-K 9071
Query: 1276 SEITDTVAASTAQSPG---------------MNLSHSASSLSLQQAFSELRR-AQMTEGP 1319
+E T+ + SPG M+ +HS +S Q FS + A M+ P
Sbjct: 9072 TESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTAS----QGFSHSQMTALMSRTP 9127
Query: 1320 NTAP------------PNFSHTGPTFPVVPPFLSSI------AGVPTTAAATAPV----- 1356
P +FS + P P S++ + +P T+ T+ +
Sbjct: 9128 GDVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTE 9187
Query: 1357 -------PATSSPPNDISTS---VIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSES 1406
P TSSPPN STS + +EVT TE+ T VVTSG ES
Sbjct: 9188 LLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEK-----LEMTNVVTSG-----YTHES 9237
Query: 1407 PVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTAT 1466
P SS+ +V + +T+S + PT + ++ S+ A + + S + T
Sbjct: 9238 P------SSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSK----LSLT 9287
Query: 1467 PGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSA 1526
PG + +S++ + +T L+SV T + + S+ SS TS P A++ + S
Sbjct: 9288 PGLMETS-ISEETSSATEKSTVLSSVPTGAT--TEVSRTEAISSSRTSIPGPAQSTMSSD 9344
Query: 1527 HSLDKTSHSST-------TGLAFS-LSAPSSSSSPGA---GVSSYISQPGGLHPLVIPSV 1575
S++ + ST T +A + + PS ++S G SS S P G H
Sbjct: 9345 TSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWP-GTHSATTQRF 9403
Query: 1576 IASTPILPQAAGPTS----TPLLPQVPSIPPLV---------QPVANVPAVQQTLIHSQP 1622
S P + GP +PL + S P + P+ + P+ HS P
Sbjct: 9404 PQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSS---HSSP 9460
Query: 1623 QP--ALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLET 1680
P +L + +D+ +P+ ++ ++ S A A+ E
Sbjct: 9461 VPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITSDE---------SLAASKATTETEA 9511
Query: 1681 SLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVST 1740
V E+T + TT+ ++ L S++ PT + ++PVVT + + +
Sbjct: 9512 IHVFENTAASHVETTSA--TEELYSSSPGFSEPTKV--------ISPVVTSSSIRDNMVS 9561
Query: 1741 TT---------------SGVKPG---TAPSKPPLTKAPVLPVGTELPAGTLP----SEQL 1778
TT S + PG T S+ + V ++P+G P +E +
Sbjct: 9562 TTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVM 9621
Query: 1779 P----PFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQ 1834
P PGP+ QS L+ D + R + ++T ++ + + + T T P
Sbjct: 9622 PSSRTSIPGPA--QSTMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPL 9679
Query: 1835 KGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSV 1894
G S G +M ++ + G + ++ SS + +
Sbjct: 9680 GTSMTFLSGTHSTMSQGLSHSEM----TNLMSRGPESLSWTSPRFVETTRSSSSLTSLPL 9735
Query: 1895 LSSSSP-ESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTAN 1953
+S SP STL+ P+ +P ++S + KTT E + +P +++T+
Sbjct: 9736 TTSLSPVSSTLLDSSPSS-PLP-VTSLILPGLVKTT--EVLDTSSEPKTSSSPNLSSTS- 9790
Query: 1954 KVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSD 2013
+ T + +TDT+K P ++ + K SH + +D
Sbjct: 9791 ----VEIPATSEIMTDTEKIHPSSN------------TAVAKVRTSSSVHESH-SSVLAD 9833
Query: 2014 PEAAF------LSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDI 2067
E ++ VDD + +P ++ +P++ + SL+ F + S + S
Sbjct: 9834 SETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEP-TFSLTPGFRETSTSEETTSIT 9892
Query: 2068 EDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRP 2127
E + + + + + S + H +S + + P +I LS
Sbjct: 9893 ETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMS---PDIITEVITRLSSSSMMS 9949
Query: 2128 TKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLH---PQQTLHPP-----GNIPE---- 2175
++ + +++ SS G + + + + H P + LH PE
Sbjct: 9950 ESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSW 10009
Query: 2176 ----------SGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPG--QGTSSTNTVG 2223
S + L P+ SPS + + SV SL PG + T ++ G
Sbjct: 10010 KSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPG 10069
Query: 2224 ATVNSQAAQAQPPAMTSSRKGTFTDDLH 2251
+++ + + +S T T+ +H
Sbjct: 10070 TSLSPNLSGTSVEILAASEVTTDTEKIH 10097
Score = 85.5 bits (210), Expect = 6e-16
Identities = 364/1815 (20%), Positives = 644/1815 (35%), Gaps = 310/1815 (17%)
Query: 597 SASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVD 656
S+ LPS S T S+++ S EE E + + + S+S +
Sbjct: 831 SSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLAS 890
Query: 657 SGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQG 716
+ + VF ++ + S H + T + ++ + P + +
Sbjct: 891 TSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNST-GSALPKISHLTGTATMS 949
Query: 717 QSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQ-------TSTSSEAT 769
Q+ + S S++ P P+ + G+ T SLS TS ++ +
Sbjct: 950 QTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSM 1009
Query: 770 TAQPVSQPQAPQVLPQVS--AGKQLPVSQPVPTIQG--------EPQIPVATQPSVVPVH 819
A + +P + + + G S +P +G +P+ T S
Sbjct: 1010 EATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTAS---SE 1066
Query: 820 SGAHFLPVGQPLPTPLLPQYPVSQIPISTP-HVSTAQTGFS-------SLPITMAAGITQ 871
+ F + + + P + STP S FS S IT+ T
Sbjct: 1067 TSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTS 1126
Query: 872 PLLTLASSATTAAIP----------GVSTVVPSQ-LPTLLQPVTQLPSQVHPQLLQPAVQ 920
LT +AT P G+ + PS P + T +V ++ V+
Sbjct: 1127 SALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVE 1186
Query: 921 S----------------MGIPAN--LGQAAEVPLSSGD-----VLYQGFPPRLPPQYPGD 957
+ IP + +G++ VPL + +G P L YP
Sbjct: 1187 TSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTL-STYPES 1245
Query: 958 SNIAPSSNVASVCIHSTVLSPPMPTEVLAT---PGYFPTVVQPYVESNLLVPMGGV---- 1010
+N PS ++ + H++ SP +A+ PG + + P +E+++ V +
Sbjct: 1246 TN-TPSIHLGA---HASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSS 1301
Query: 1011 GGQVQVSQPGGSLAQA---PTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASS 1067
G +++ PG + + PTT + T +QV+ V +T P T S+
Sbjct: 1302 GSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSS-AQVSTPHSVRTLRTTENHPKT-ESA 1359
Query: 1068 VDSAHSDVASGMSDGNENVPSSSGRHEGRTTKR----HYRKSVRSRSRHEKTSRPKLRIL 1123
+A+S S N P++ TT+ HY K S E S P
Sbjct: 1360 TPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAP----- 1414
Query: 1124 NVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVRE 1183
V + T + + + +L D P E + + + + +++
Sbjct: 1415 -------GPVSVVIPT-SPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLS---- 1462
Query: 1184 IIEKADEMLSEDVSV----EPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQ 1239
+EM S D+ + P + + S S+ + ++++ Q
Sbjct: 1463 -TSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRN-TDSTTLDQH 1520
Query: 1240 IGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSAS 1299
+GI S GR ++ VP + L + + S I + A S M+ +H
Sbjct: 1521 LGI---------RSLGRTGDLTTVPITPL--TTTWTSVIEHSTQAQDTLSATMSPTHVTQ 1569
Query: 1300 SLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPAT 1359
SL Q T P +A P SH +P + G ++ A T P+T
Sbjct: 1570 SLKDQ-----------TSIPASASP--SHLTEVYPEL-----GTQGRSSSEATTFWKPST 1611
Query: 1360 SSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSI--- 1416
+ +I T + T P + G +S+ VT G +P + SP +S ++
Sbjct: 1612 DTLSREIETGPTNIQSTPPMDNTTTG--SSSSGVTLGIAHLPIGTSSPAETSTNMALERR 1669
Query: 1417 TIPAVVSIS-------TTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGP 1469
+ A VS++ T++P + S + S+ L S T T +S G S
Sbjct: 1670 SSTATVSMAGTMGLLVTSAPGRSISQSLGRV---SSVLSESTTEGVTDSSKGSS------ 1720
Query: 1470 KPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSL 1529
P + +Q G+T + ++L S ST SI L+SS +TP + E + S
Sbjct: 1721 --PRLNTQ---GNTALSSSLEPSYAEGSQMST----SIPLTSSPTTPDV-EFIGGSTFWT 1770
Query: 1530 DKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPT 1589
+ + T+ ++ S + SSS+ + ++ G L S+ +P
Sbjct: 1771 KEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSP--------- 1821
Query: 1590 STPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGI 1649
P + P + ++N P +L L + HT + + G+
Sbjct: 1822 ----TPSMEVTPWISLTLSNAPNTTDSLD--------LSHGVHTSSAGTLATDRSLNTGV 1869
Query: 1650 DDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTST 1709
LE + S + H S++ + S++ P T+A LTST
Sbjct: 1870 TRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGN 1929
Query: 1710 CLPPTNLPLGTVALPVTPVVTPGQVSTP-----------------VSTTTSGVKPGTAP- 1751
LP ++ PV V++ G S P V T+T ++ T P
Sbjct: 1930 RAISLTLPFSSI--PVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPL 1987
Query: 1752 ----SKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQ--SQQPLEDLDAQL--RRT 1803
S+ + P + P+ + G S + S LE LD+ + R
Sbjct: 1988 HAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNA 2047
Query: 1804 LSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQ----VKEGPVLATSSGAGVFKMGR 1859
++ + +T+++ P + T+++EA + GVS E P+ + +S + +
Sbjct: 2048 ITSWLWDLTTSL-PTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQR-- 2104
Query: 1860 FQVSVAADGAQKEGKNK-SEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGIS 1918
G Q + + DA SV + SE+ V +S S E L + + G++
Sbjct: 2105 -NPETETHGPQNTAASTLNTDASSV---TGLSETPVGASISSEVPLPMAITSRSDVSGLT 2160
Query: 1919 SDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKT---------EDKITD 1969
S+ + TAS A TK+ R T+ + F ++K T+
Sbjct: 2161 SESTANPSLGTASSA------GTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTN 2214
Query: 1970 TKKEGPV--ASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGS 2027
T+ PV A PP + V VI S P+ PS D E +S + +
Sbjct: 2215 TETSIPVNSAGPPGL---STVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTT 2271
Query: 2028 GSPHS----PHQLSSK--SLPSQNLSQSLSN----------------------------- 2052
S + H+L+S+ +P +S ++S
Sbjct: 2272 HSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVL 2331
Query: 2053 --SF-NSSYMSSDNESDIEDEDLKLELRRLRD--KHLKEIQDLQSRQKHEIESLYTKLGK 2107
SF +S +S DNE+ ++ D+ L+ R+ + DL + TK
Sbjct: 2332 TASFTETSTVSLDNETTVKTSDI-LDARKTNELPSDSSSSSDLINTSIASSTMDVTKTAS 2390
Query: 2108 VPPAVI------IPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVL 2161
+ P I P+ S R + PT + + ++ S S+ + + L G + S L
Sbjct: 2391 ISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTL 2450
Query: 2162 HPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGA------ISVPSLSAPGQG 2215
P H P + LL +P + + S T+ G V S+ APG
Sbjct: 2451 PPFTITH-----PVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTW 2505
Query: 2216 TSSTNTVGATVNSQA 2230
TS VG+T + A
Sbjct: 2506 TS----VGSTTDLPA 2516
Score = 79.7 bits (195), Expect = 3e-14
Identities = 189/902 (20%), Positives = 325/902 (36%), Gaps = 127/902 (14%)
Query: 1235 SMPQQIGIPTSSLTQVVH---------SAGRRFIVSPVPESRLRESKVFPSEITDTVAAS 1285
S+P +GI SS ++ S G + +P SR + E + +
Sbjct: 6720 SLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTT 6779
Query: 1286 TAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAG 1345
LS + + +FS + M T+PP S T P ++S+
Sbjct: 6780 VMNKDPEILSWTIPPSIEKTSFSS---SLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLT 6836
Query: 1346 ----VPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVA----TSTGVVTSGG 1397
+ T T+P P TSSPPN STS E+ E+ A A TST
Sbjct: 6837 PSLVMTTDTLGTSPEPTTSSPPNLSSTS---HEILTTDEDTTAIEAMHPSTSTAATNVET 6893
Query: 1398 LPIPPVSESPVL--------------SSVVSSITIPAVVSIST----------------- 1426
S+S VL +S + T+ +S+S+
Sbjct: 6894 TSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGL 6953
Query: 1427 --TSPSLQVPTST-SEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGST 1483
TS S ST + IV+S + VS T ++ G T+ PGP V+ + ST
Sbjct: 6954 RETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEI---ST 7010
Query: 1484 TVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFS 1543
L + T T S STS TL T+ S +HS+ T F
Sbjct: 7011 RTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTL--TLDTSTTKSQAKTHSTLT-QRFP 7067
Query: 1544 LSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAG--PTSTPLLPQVPSIP 1601
S ++ S G G S+ S P +P +PS+++ LP P S+ L + S P
Sbjct: 7068 HSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLS----LPATTSPPPISSTLPVTISSSP 7123
Query: 1602 -PLVQPVANVPAVQQTLIHSQPQ--------------PALLPNQPHTHCPEVDSDTQPKA 1646
P+ + + P ++H+ P+ L + T+ V T A
Sbjct: 7124 LPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAA 7183
Query: 1647 PGIDDIKTLEEKLRSLFSEHSSSGA----------QHASVSLETSLVIESTVTPGIPTTA 1696
++ + E S ++ +S A + +V++ T +E++ ++
Sbjct: 7184 SNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISS 7243
Query: 1697 VAPSKLLT--STTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGT----A 1750
++P T S ++ T+ L V++ T ++ +V++ T+ SG T
Sbjct: 7244 LSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEI 7303
Query: 1751 PSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSL-----TQSQQPLEDLDAQLRRTLS 1805
+ + K P P+ E T+ ++ PP T + L + + + L
Sbjct: 7304 STTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLP 7363
Query: 1806 PEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVA 1865
IT + G + P+++ T P SQ+ +++ S + S +
Sbjct: 7364 HSEITTLVSRGAGDVPRPSSLPVEETSPPS--SQLSLSAMISPSPVSSTLPASSHSSSAS 7421
Query: 1866 ADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPE----------STLVKPEPN-GITI 1914
G+ K+ + E TS LSS+S E + + P N +T
Sbjct: 7422 VTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTK 7481
Query: 1915 PGISSDVPESAHK----TTASEAKSDTGQPTKVGRFQVTTTANKVG--RFSVSKTEDKIT 1968
G SS ES + ++A S G + +G V+T + R S+ +T
Sbjct: 7482 VGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLT 7541
Query: 1969 DTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEP---SHLNGPSSDPEAAFLSRDVDD 2025
+E + + E + + + E+S S S PE + +S+D+
Sbjct: 7542 TRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISI 7601
Query: 2026 GS 2027
G+
Sbjct: 7602 GT 7603
Score = 79.3 bits (194), Expect = 4e-14
Identities = 324/1519 (21%), Positives = 539/1519 (35%), Gaps = 270/1519 (17%)
Query: 592 QVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQ-QLQYQQPSISVL 650
+ E +S+S+T I + ST +P STT + P E+ + + Q P +
Sbjct: 7280 RTEVTSSSRTSISG-SAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSE 7338
Query: 651 SDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQ-----AHSTGTVPGHIPSTVQAQSQPH 705
S T+D+ T S V + T++ H + + G VP PS++ +
Sbjct: 7339 STFTLDTST-----TPSLVITHSTMTQRLPHSEITTLVSRGAGDVPR--PSSLPVEETS- 7390
Query: 706 GVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTS 765
PPSS + PS VSS+ P + P Q + S
Sbjct: 7391 ---PPSSQLSLSAMISPSP-----VSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAE 7442
Query: 766 SEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFL 825
E ++ +S S ++ + V T +I + +V V + +
Sbjct: 7443 PETSSPPSLS-----------STSVEILATSEVTT--DTEKIHPFSNTAVTKVGTSSS-- 7487
Query: 826 PVGQPLPTPLLPQYPVSQIPISTPHVST-AQTGFSSLPITMAAGITQPLLTLASSATTAA 884
G P+ +LP ++ + +S T S+L T A T+ + + +S+ T
Sbjct: 7488 --GHESPSSVLPDSETTKATSAMGTISIMGDTSVSTL--TPALSNTRKIQSEPASSLTTR 7543
Query: 885 IPGVSTVVPSQLPTLLQPV--------------TQLPSQVHPQLLQPAVQSMGIPANLGQ 930
+ ST + L T V T+ S + P +M ++G
Sbjct: 7544 LRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGT 7603
Query: 931 AAEVPLSSGDVLYQGFPPRLPPQY-PGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPG 989
+ SS VL + + Q P +S + + N+ + TP
Sbjct: 7604 IPRISASS--VLTESAKMTITTQTGPSESTLESTLNLNTA----------------TTPS 7645
Query: 990 YFPT---VVQPYVESNLLVPMG-GVGGQ-------VQVSQPGGSLAQAPTTSSQQAVLES 1038
+ T V+Q + + MG G GG V+ + P S P +S V S
Sbjct: 7646 WVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPV--S 7703
Query: 1039 TQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTT 1098
T ++ + P+ P+ V + P T + ++ S S S+ HE TT
Sbjct: 7704 TTFLAHIPPS-PLPVTSLLTSGPATTTDILGTSTEPGTSSSSS------LSTTSHERLTT 7756
Query: 1099 KRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEE 1158
Y+ + + + H T+ + S+ G + L +
Sbjct: 7757 ---YKDTAHTEAVHPSTNTGGTNVATTSS-GYKSQSSVLA----------------DSSP 7796
Query: 1159 IATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFS 1218
+ T D + +F++ R E A + GL G + S
Sbjct: 7797 MCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTP-----------GLRESSGSEGTS-S 7844
Query: 1219 GSQKLEGEFKQPIPAS---SMPQQIGIPTSSLTQVVHSAGRR----FIVSPV-PESRLRE 1270
G++ K P A+ S IP + + + R F SPV ES
Sbjct: 7845 GTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEIT 7904
Query: 1271 SKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQ-MTEGPNT----APPN 1325
S + T ++ S + + ++ Q FS + + M GP +PP
Sbjct: 7905 MNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPL 7964
Query: 1326 FSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAG 1385
T P+F ++ ++ A T+P P +S+ P IS+S + T +G
Sbjct: 7965 LEKTRPSFSLM-----------SSPATTSPSPVSSTLPESISSSPLPV-----TSLLTSG 8008
Query: 1386 VATSTGVVTSGGLPIPPVSESPV-LSSVVSSITIPAVVSIST--TSPS-----LQVPTST 1437
+A +T ++ PV+ SP LSS I + V+ T T PS V TS+
Sbjct: 8009 LAKTTDMLHKSS---EPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSS 8065
Query: 1438 SEIVVSSTALYPSVT--------VSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATL 1489
S +S L S T +++T ST+TPG + + + S T+G
Sbjct: 8066 SGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRK 8125
Query: 1490 TSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSS 1549
TS S TS A+++S LS PT A T VS + +S +S +G A +P +
Sbjct: 8126 TSSSEGTSL---ATEMSTVLS---GVPTGA-TAEVSRTEVTSSSRTSISGFAQLTVSPET 8178
Query: 1550 SSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVAN 1609
S+ I++ L I + A I Q P STP I V
Sbjct: 8179 STET-------ITR---LPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVET 8228
Query: 1610 VPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSS 1669
V Q HS+ L+ P P +++ + SL S +++
Sbjct: 8229 HSTVTQRFSHSE-MTTLVSRSP-------GDMLWPSQSSVEETSSAS----SLLSLPATT 8276
Query: 1670 GAQHASVSL-----ETSLVIESTVTPG--IPTTAVAPSKLL-TSTTSTCLPPTNLPLGTV 1721
S +L SL + S + PG I T + S+ TS+TS ++ L T+
Sbjct: 8277 SPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTL 8336
Query: 1722 ALPV-TPVVTPG--QVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAG-TLPSEQ 1777
V T + P T V T+ SG + ++ T P+GT G T S
Sbjct: 8337 EDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSIS 8396
Query: 1778 LPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMI-------TVTSAVGP------------- 1817
F S Q +P L + LR T S E I TV S V
Sbjct: 8397 TSDFFETSRIQI-EPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVIS 8455
Query: 1818 ---VSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGK 1874
SM+ P T + + ++++ P++ S+ + + + + GA EG
Sbjct: 8456 SRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAI------TIETGSPGATSEGT 8509
Query: 1875 NKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAK 1934
+ + + + + S +S S S +TL+ P + P + S V E AS
Sbjct: 8510 LTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPS-VEE------ASSVS 8562
Query: 1935 SDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIP 1994
S P +T S+S + +T GPV + ++
Sbjct: 8563 SSLSSPAMTSTSFFSTLPE-----SISSSPHPVTALLTLGPVKTTD-----------MLR 8606
Query: 1995 KKEKPELSEPSHLNGPSSD 2013
+PE S P +L+ S++
Sbjct: 8607 TSSEPETSSPPNLSSTSAE 8625
Score = 79.0 bits (193), Expect = 5e-14
Identities = 242/1084 (22%), Positives = 402/1084 (37%), Gaps = 171/1084 (15%)
Query: 1232 PASSMPQQIGIPTSSLTQVVHSAGRRFIVS--PVPESRLRESKV--FPSEITDTVAASTA 1287
P ++ + SS+T + + I S P+P + S V SE T + TA
Sbjct: 2113 PQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTA 2172
Query: 1288 QSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP-PNFSH----TGPTFPVV---PPF 1339
S G L+ + S + + S +M + P T P SH T + PV PP
Sbjct: 2173 SSAGTKLTRTISLPTSESLVS----FRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPG 2228
Query: 1340 LSSIAG----VPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTS 1395
LS++A P+ A + P + S P+ T++ S T +++ T +TS
Sbjct: 2229 LSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTI--SHFPEKTTHSFRTISSLTHELTS 2286
Query: 1396 GGLPIPPVSESPVLSSVVS----SITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSV 1451
PIP S +S+ + SIT+ +I++ +P+ T+ +ST +
Sbjct: 2287 RVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNE 2346
Query: 1452 TVSATSASAGGSTATPGPKPPA----VVSQQAAGST-----TVGATLTSVS--TTTSFPS 1500
T TS P + +++ A ST T + TS+S T +S PS
Sbjct: 2347 TTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPS 2406
Query: 1501 TASQLSIQLSSSTSTPTLAETVVVSA--HSLDKTSH---SSTTGLAFSLSAPSSSSS--- 1552
S Q+ +ST+ A + VS+ +SLD S+ + +T F+++ P +SS
Sbjct: 2407 LFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALL 2466
Query: 1553 ----PGAGVSSYISQP--GGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQP 1606
P S+ +S G +P SV+ S P ST LP + + P
Sbjct: 2467 AWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLK--TSP 2524
Query: 1607 VANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEH 1666
+L+ S +PA PH V + + + T E K + H
Sbjct: 2525 AGEA----HSLLASTIEPATAFT-PHLSAAVVTGSSATSEASL--LTTSESK-----AIH 2572
Query: 1667 SS--------SGAQ-HASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLP 1717
SS SGA S + E+ LV+ T + + + +L ST ST PP+ P
Sbjct: 2573 SSPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVST--PPSKFP 2630
Query: 1718 -LGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSE 1776
GT++ P + P + P++ T T+ PL T+ S+
Sbjct: 2631 STGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLV--------------TIASD 2676
Query: 1777 QLPPFPGPSLTQSQQPLEDLDAQLRRTLS-PEM----IT---VTSAVGPVSMAAPTAITE 1828
L P +LT S+ + DA + +T+S P+ IT VT + S +P+ I
Sbjct: 2677 SLGTVPETTLTMSET--SNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVA 2734
Query: 1829 AGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESS 1888
+G V + A ++G+ VF E+S
Sbjct: 2735 PRNTTYEGSITVALSTLPAGTTGSLVFSQSS--------------------------ENS 2768
Query: 1889 TSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQV 1948
+ + V SS+ E V P G G++S + T ++ K+ + P + +V
Sbjct: 2769 ETTALVDSSAGLERASVMPLTTGSQ--GMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEV 2826
Query: 1949 TTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLN 2008
T + T +++T T+ P P V P + L P
Sbjct: 2827 TAMSEI--------TTNRLTATQSTAPKGIP------------VKPTSAESGLLTPV--- 2863
Query: 2009 GPSSDPEAAFLSRDVDDGS-GSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDI 2067
SS P AF S + G P S +PS + ++S S +++ +SD
Sbjct: 2864 SASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLD-TKSASLPTPGQSLNTIPDSDA 2922
Query: 2068 EDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRP 2127
L ++ + + ++ +S T + P P A R P
Sbjct: 2923 STASSSLSKSPEKNPRARMMTSTKAISASSFQS--TGFTETPEGSASPSMA--GHEPRVP 2978
Query: 2128 TKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQL------ 2181
T G S S+ P + S ++ S+ TL G SG +
Sbjct: 2979 TSGTGDPRYASESMSYPDPSKAS--SAMTSTSLASKLTTLFSTGQAARSGSSSSPISLST 3036
Query: 2182 ---LQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAM 2238
L P+ S+ S F P++ Q ++ T + +T+N +Q +PP +
Sbjct: 3037 EKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNM--SQEEPPEL 3094
Query: 2239 TSSR 2242
TSS+
Sbjct: 3095 TSSQ 3098
Score = 77.8 bits (190), Expect = 1e-13
Identities = 273/1214 (22%), Positives = 441/1214 (36%), Gaps = 211/1214 (17%)
Query: 1277 EITDTVAASTAQSPG----MNLSH-----SASSLSLQQAF-------SELRRAQMTEGPN 1320
E+T ++ + + +P ++LSH SA +L+ ++ S L T +
Sbjct: 1826 EVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKS 1885
Query: 1321 TAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTE 1380
+ N +HT T+ SSI P T+A A TS+P N + S+ ++P E
Sbjct: 1886 LSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNR-AISLTLPFSSIPVE 1944
Query: 1381 EGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSIST------TSPSLQVP 1434
E I STG+ + + P++ SP IT P +V ST T P V
Sbjct: 1945 EVI-----STGITSGPDINSAPMTHSP--------ITPPTIVWTSTGTIEQSTQPLHAVS 1991
Query: 1435 TSTSEIVVSSTALYPSVTVSAT-----SASAGGSTATPGPKPPAVVSQQAAGSTTVGATL 1489
+ + ST SV VSA+ S S+G ST++P S ++ +
Sbjct: 1992 SEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSP------------YSSASLESLD 2039
Query: 1490 TSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSL-SAPS 1548
+++S + S L+ L ++T T + S HS S+ S+T F L SA S
Sbjct: 2040 STISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHS--GVSNPSSTTTEFPLFSAAS 2097
Query: 1549 SSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVA 1608
+S++ + P + + +S G + TP+ + S PL +
Sbjct: 2098 TSAAKQRNPETETHGPQNTAASTLNTDASS------VTGLSETPVGASISSEVPLPMAIT 2151
Query: 1609 NVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEH-- 1666
+ V S P+L S K + T E + ++
Sbjct: 2152 SRSDVSGLTSESTANPSL----------GTASSAGTKLTRTISLPTSESLVSFRMNKDPW 2201
Query: 1667 --SSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALP 1724
S H + + ETS+ + S PG+ T A S ++ + + G ++P
Sbjct: 2202 TVSIPLGSHPTTNTETSIPVNSAGPPGLSTVA---SDVIDTPSD----------GAESIP 2248
Query: 1725 VTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGP 1784
VS S T P K + + + EL + ++ P PG
Sbjct: 2249 T--------VSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHEL------TSRVTPIPGD 2294
Query: 1785 SLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTA-ITEAGTQPQKGVSQVKEG 1843
++ S + A TL E T+TSA S TA TE T + VK
Sbjct: 2295 WMS-SAMSTKPTGASPSITLG-ERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTS 2352
Query: 1844 PVL----------ATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESS 1893
+L +SS + + + A K S S+ +++S S
Sbjct: 2353 DILDARKTNELPSDSSSSSDLIN------TSIASSTMDVTKTASISPTSISGMTASSSPS 2406
Query: 1894 VLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDT-GQPTKVGRFQVT--- 1949
+ SS P+ E N T P +SS+ T + + S+ G P+ + F +T
Sbjct: 2407 LFSSDRPQVPTSTTETNTATSPSVSSN-------TYSLDGGSNVGGTPSTLPPFTITHPV 2459
Query: 1950 -------TTANKVGRFSVSKTEDKIT---DTKKEGPVASPPFMDLEQAV-----LPAVIP 1994
+ V FS + D + T V S P +V LPA+
Sbjct: 2460 ETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGF 2519
Query: 1995 KKEKPELSEPSHLNGPSSDPEAAF---LSRDVDDGSGSPHSPHQLS---SKSLPSQNLSQ 2048
K P E L + +P AF LS V GS + L+ SK++ S +
Sbjct: 2520 LKTSP-AGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTP 2578
Query: 2049 SLSNSFNSSYMSSDNESDI---EDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKL 2105
+ S + S+ ES + E D L + L + + S + S T
Sbjct: 2579 TTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTI--LFSTVSTPPSKFPSTGTLS 2636
Query: 2106 GKVPPAVI-IPPAAPLSGRRRRPTKSKGSK-------SSRSSSLGNKSPQLSGNLSGQSA 2157
G P ++ PA PL+ PT S + + S SLG P+ + +S S
Sbjct: 2637 GASFPTLLPDTPAIPLTA--TEPTSSLATSFDSTPLVTIASDSLGT-VPETTLTMSETSN 2693
Query: 2158 ASVLHPQQTLHPPGNIPE-SGQNQLLQPLKPSPSSDNLYSA---FTSDGAISVPSLSAPG 2213
L + +P +IP + Q PL PS +S + A T +G+I+V + P
Sbjct: 2694 GDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLP- 2752
Query: 2214 QGTSSTNTVGATVNSQAAQ-AQPPAMTSSRKGTFTDDLHKLV---DNWARDAMNLSGRRG 2269
T G+ V SQ+++ ++ A+ S G + L A SG
Sbjct: 2753 -----AGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTH 2807
Query: 2270 SKGHMNYE------GPG-------------MARKFSAPGQLCISMTSNLGG-SAPISAAS 2309
S G + PG A + +AP + + TS G P+SA+S
Sbjct: 2808 STGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASS 2867
Query: 2310 ATSLGHFTKSMCPPQQYGFPATPFGAQWSGTGGPAPQPLGQFQPVGTASLQNF---NISN 2366
+ S + + PP +G P + ++S P+ P SL + S
Sbjct: 2868 SPSKAFASLTTAPP-TWGIPQSTLTFEFSEV--PSLDTKSASLPTPGQSLNTIPDSDAST 2924
Query: 2367 LQKSISNPPGSNLR 2380
S+S P N R
Sbjct: 2925 ASSSLSKSPEKNPR 2938
Score = 75.9 bits (185), Expect = 5e-13
Identities = 313/1561 (20%), Positives = 539/1561 (34%), Gaps = 244/1561 (15%)
Query: 585 EESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQ--HQQLQY 642
E S + V SS + + AS+ I S S T P E Q H +
Sbjct: 8961 EPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPT-PRETSTSQEIHSATKP 9019
Query: 643 QQPSISVLSDGTVDSGQGSSVFTESRVSS--QQTVSYGSQHEQAHSTGTVPGHIPSTVQA 700
L+ T++ + V + SR S Q T+S E T P ST
Sbjct: 9020 STVPYKALTSATIEDSM-TQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMT 9078
Query: 701 QSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSS--SQPIQHPQQQQGIQQTAPPQQTVQYS 758
+ G P + ++G S++ ++G S SQ H Q + +T + +
Sbjct: 9079 ITTQTG--SPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHP 9136
Query: 759 LSQTSTSSEATTAQPVSQPQAP--QVLPQVSAGKQLPVSQPVPT-------IQGEPQIPV 809
+ ++S+ + + PV +P LP LPV+ + + + G P
Sbjct: 9137 SVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPE 9196
Query: 810 ATQPSVVPVHSGAHFLPVGQPLP-------TPLLPQYPVSQIPISTPHVSTAQTGFSSLP 862
+ P + S A L + + T ++ + P S S SS+
Sbjct: 9197 TSSPPNLSSTS-AEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMG 9255
Query: 863 ITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSM 922
IT G T L + + + T+ I S + S P L++ T + + A +
Sbjct: 9256 ITYPTGDTNVLTSTPAFSDTSRIQTKSKL--SLTPGLME--TSISEET-----SSATEKS 9306
Query: 923 GIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPT 982
+ +++ A +S + + R P S ++ +++ ++ ST L+ T
Sbjct: 9307 TVLSSVPTGATTEVSRTEAISSS---RTSIPGPAQSTMSSDTSMETITRISTPLTRKEST 9363
Query: 983 EVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGV 1042
++ TP P+ G Q + S A P T S +TQ
Sbjct: 9364 DMAITPKTGPS---------------GATSQGTFTLDSSSTASWPGTHSA-----TTQRF 9403
Query: 1043 SQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNEN----VPSSSGRHEGRTT 1098
Q P++ + P+ L+ +S S + S S + + PS S H
Sbjct: 9404 PQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSS-HSSPVP 9462
Query: 1099 KRHYRKSVRSRSRH--------EKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFD 1150
S+ ++ E TS P + I + + + + T + F
Sbjct: 9463 VTSLFTSIMMKATDMLDASLEPETTSAPNMNITS----DESLAASKATTETEAIHVF--- 9515
Query: 1151 LDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQ 1210
+ + T + + S +V + + + VS G G+ ++
Sbjct: 9516 -ENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIE 9574
Query: 1211 GKDDYGFSGSQKLEGEFKQPIPASSMPQQI-------GIPTSSLTQVVHSAGRRFIVSPV 1263
+ + + E Q I +S+ + P S T+V+ S+ R I P
Sbjct: 9575 IESMSSLTPGLR-ETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSS-RTSIPGPA 9632
Query: 1264 PES-----------RLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFS---- 1308
+ RL S + T+ T G +L+ S +L L + +
Sbjct: 9633 QSTMSLDISDEVVTRLSTSPIMTESAEITITTQT----GYSLATSQVTLPLGTSMTFLSG 9688
Query: 1309 -------ELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPAT-- 1359
L ++MT + P + S T P F SS+ +P T + + PV +T
Sbjct: 9689 THSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTSLS-PVSSTLL 9747
Query: 1360 -SSPPNDIS-TSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSIT 1417
SSP + + TS+I + G+ +T V+ + P S SP LSS +S+
Sbjct: 9748 DSSPSSPLPVTSLI-----------LPGLVKTTEVLDTSSEP--KTSSSPNLSS--TSVE 9792
Query: 1418 IPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQ 1477
IPA I T + + ++T+ V +++ SV S +S A T P++
Sbjct: 9793 IPATSEIMTDTEKIHPSSNTAVAKVRTSS---SVHESHSSVLADSETTIT---IPSMGIT 9846
Query: 1478 QAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSST 1537
A TTV + + S T P+ + + TP ET + S + TS + T
Sbjct: 9847 SAVDDTTVFTSNPAFSETRRIPTEPT--------FSLTPGFRET----STSEETTSITET 9894
Query: 1538 TGLAFSL--SAPSSSSSPGAGVSSYISQPGG----LHPLVIPSVIASTPILPQAAGPTST 1591
+ + + + SA + S S+ I P + P +I VI + T
Sbjct: 9895 SAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQM 9954
Query: 1592 PLLPQVPSIPPLVQPVANVPAVQQTLI--HSQPQPALLPNQPHTHCPEVDSDTQPKAPGI 1649
+ Q S Q + L HS P L ++ T + K+
Sbjct: 9955 TITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKS--- 10011
Query: 1650 DDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLT----S 1705
SLF E +SS + S+ + TS + ST+ IP+++ + + LLT
Sbjct: 10012 -----------SLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVK 10060
Query: 1706 TTSTCLPP-----TNLPLGTVALPVTPVVT---------PGQVSTPVSTTTSGVKPGTAP 1751
TT T P NL +V + VT T V TT+SG + ++
Sbjct: 10061 TTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSV 10120
Query: 1752 SKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRT-LSPEMIT 1810
S PVGT P + +P L + R+T +S + +
Sbjct: 10121 SIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSS 10180
Query: 1811 VTSAVGPVSMAAPTAITEAGTQ---------------------PQKGVSQVKEGPVLATS 1849
VT P S + + + T P ++ P + S
Sbjct: 10181 VTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITES 10240
Query: 1850 SGAGVFKMGRFQVSV-------------AADGAQKEGKNKSEDAKSVHFESSTSESSVLS 1896
+G F RF +SV +A+ S F ++ ++
Sbjct: 10241 TGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISG 10300
Query: 1897 SSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVG 1956
S SP S + P T+ I+ +P S +S + T T ++T+++
Sbjct: 10301 SGSPFSR-TESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPY 10359
Query: 1957 RFSVS-KTEDKITD-----------TKKEGPVASPPFMD---LEQAVLPAVIPKKEKPEL 2001
R S TE T+ + + G +S P +D E L V + P L
Sbjct: 10360 RVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSL 10419
Query: 2002 S 2002
S
Sbjct: 10420 S 10420
Score = 72.8 bits (177), Expect = 4e-12
Identities = 363/1832 (19%), Positives = 631/1832 (34%), Gaps = 301/1832 (16%)
Query: 617 STTSASVSTQVEPEEPE----ADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQ 672
+T A+V T + E + AD H + P + G + F E+R+ ++
Sbjct: 5717 NTAVANVGTSISGHESQSSVPADSHTS-KATSPMGITFAMGDTSVSTSTPAFFETRIQTE 5775
Query: 673 QTVSY---------GSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA---QGQSQG 720
T S + T TV +P+T + V S S+
Sbjct: 5776 STSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKM 5835
Query: 721 QP--SSSSLTGVSSSQPIQHPQQQQGIQQTAP----PQQTVQYSLSQTST---------- 764
P S+ ++T +S+ + + QT P Q T+ S T++
Sbjct: 5836 SPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQ 5895
Query: 765 ----SSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQI--------PVATQ 812
S E TT ++ + Q P V P+P I + P +
Sbjct: 5896 RFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSAL 5955
Query: 813 PSVVPVHSGAH----FLPVGQPLPTPLLPQYPV--SQIPISTPHVSTAQTGFSSLPITMA 866
P + SG L L T LP +I S +T FS
Sbjct: 5956 PVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETN 6015
Query: 867 AGITQPLLTLASSATTAAIPG----------------VSTVVPSQLPTL------LQPVT 904
G T + L SS + + P VST P T P+T
Sbjct: 6016 MGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLT 6075
Query: 905 -QLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQG--FPP------RLPPQYP 955
+L ++ +S + +++ A +S +V Y F P + P P
Sbjct: 6076 PELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISP 6135
Query: 956 GDSNIAPSSNVASVCIHSTVLSPPMP------------TEVLATPGYFPTV-VQPYVESN 1002
S+ +S ++ H T+ + P T +AT P+ Q +V+S
Sbjct: 6136 EASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSE 6195
Query: 1003 LLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPT 1062
M V + P S +A + SSQ +L +T P V T T
Sbjct: 6196 TTSVMNNDLNDVLKTSPF-SAEEANSLSSQAPLLVTTS---------PSPVTSTLQEHST 6245
Query: 1063 TLASSVDSAHSDVASGMSDGNENV-PSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLR 1121
+ SV S + + ++D + N+ P + R T + + + H +
Sbjct: 6246 SSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVAN 6305
Query: 1122 ILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERE---SFV 1178
+ S+ + ++ K + ++T M + + IE E S +
Sbjct: 6306 VGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLI 6365
Query: 1179 DQVREIIEKADEMLSEDVS-VEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMP 1237
++RE S D S V + + + + S ++G K + +
Sbjct: 6366 FRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTS- 6424
Query: 1238 QQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITD--TVAASTAQSPGMNLS 1295
T S+T + AG E R ++ P T T+ T+ + +
Sbjct: 6425 ------TRSVTMLSTFAGLT-----KSEERTIATQTGPHRATSQGTLTWDTSITTSQAGT 6473
Query: 1296 HSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAP 1355
HSA + FS+L + +T + P S T P SS+ +P + + P
Sbjct: 6474 HSA----MTHGFSQLDLSTLT---SRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPS-P 6525
Query: 1356 VPAT---SSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSV 1412
VP T S P + + + + + V T + +A VA+ +PP
Sbjct: 6526 VPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVAS-----------LPP---------- 6564
Query: 1413 VSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGS-----TATP 1467
+ S S ++PT TSE + + +YPS ++ T+ S ++ P
Sbjct: 6565 ------------NLGSTSHKIPT-TSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVP 6611
Query: 1468 GPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAH 1527
P V+ S + T+ S TS P ++ I++ S+ S LA + ++
Sbjct: 6612 AYSEPPKVTSPMVTSFNIRDTIVS----TSMPGSSEITRIEMESTFS---LAHGLKGTST 6664
Query: 1528 SLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSS-YISQPGGLHPLVIPSVIAST-PILPQA 1585
S D + + + L+ ++ +S SS S PG H P + P LP +
Sbjct: 6665 SQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPIS 6724
Query: 1586 AGPTSTPLLPQVPSI-PPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHC--------- 1635
G T + + + PPL + S+ + Q H
Sbjct: 6725 LGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKD 6784
Query: 1636 PEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTT 1695
PE+ S T P P I+ ++ FS S + ++L TP T+
Sbjct: 6785 PEILSWTIP--PSIE---------KTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTS 6833
Query: 1696 AVAPSKLLTSTT-------STCLPP----TNLPLGTVALPVTPV----VTPGQVSTPVST 1740
+ PS ++T+ T +T PP T+ + T T + + +T V T
Sbjct: 6834 LLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVET 6893
Query: 1741 TTSG---VKPGTAPSKPPLTKAPVLPVG----TELPAGTLPSEQLPPFPGPSLTQSQQPL 1793
T+SG A S+ AP+ T + S + S L
Sbjct: 6894 TSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGL 6953
Query: 1794 EDLDAQLRRTLSPEMITVTSAV--GPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSG 1851
+ + S + V S V G + + T +T +G G SQ P ++T +
Sbjct: 6954 RETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTM 7013
Query: 1852 AGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSES-----SVLSSSSPES---T 1903
+F S + G + S ++ ++ST++S S L+ P S T
Sbjct: 7014 TRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTT 7073
Query: 1904 LVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSV--- 1960
L+ P ++ S + + + + T P VT +++ + S+
Sbjct: 7074 LMSRGPGDMSWQS-SPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTS 7132
Query: 1961 -SKTEDKITDTKKEGPVASPPFMD--------------LEQAVLPAVIPKKEKPELSEPS 2005
T + T E +SPP + +AV P+ E+
Sbjct: 7133 SPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSG 7192
Query: 2006 HLNGPSS---DPEAA------FLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNS 2056
H PSS D E + F++ +D + + +PH L + + +++S SLS
Sbjct: 7193 H-ESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESIS-SLSPKLRE 7250
Query: 2057 SYMSSDNESDIEDEDLKLELRRLRDKHLKEIQ-----------DLQSRQKHEIESLYTKL 2105
+ S + S IE + E+ + + +S EI S K+
Sbjct: 7251 TGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEI-STTRKI 7309
Query: 2106 GKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLG-NKSPQL---------------S 2149
K P + I+ ++ ++ + + T GS S + +L + +P L
Sbjct: 7310 IKFPTSPILAESSEMTIKTQ--TSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEI 7367
Query: 2150 GNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSL 2209
L + A V P +L P S Q L + PSP S L ++ S A SV SL
Sbjct: 7368 TTLVSRGAGDVPRP-SSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSA-SVTSL 7425
Query: 2210 SAPGQGTSSTNTVGATVNSQAAQAQPPAMTSS 2241
PGQ +T + A+ + + PP+++S+
Sbjct: 7426 LTPGQ-VKTTEVLDASAEPET--SSPPSLSST 7454
Score = 71.6 bits (174), Expect = 8e-12
Identities = 310/1500 (20%), Positives = 516/1500 (34%), Gaps = 222/1500 (14%)
Query: 605 QLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVF 664
++P T + +++TQ P PE+ H L + T+ G S
Sbjct: 5251 EIPRVFTSSIKTKSAEMTITTQASP--PESASHSTLPLDTST-------TLSQGGTHSTV 5301
Query: 665 TESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSS 724
T+ S+ T G T P S+V + + PS V+ Q PSS
Sbjct: 5302 TQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSS 5361
Query: 725 ---------------------SSLTGVSSSQP----IQHPQQQQGIQQTAPPQQTVQYSL 759
+S V+SS P I H ++ + TA + + +S
Sbjct: 5362 PLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITH-ERPATYKDTAHTEAAMHHST 5420
Query: 760 SQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVH 819
+ T+ + + SQ VL K P+ T+ G+ + +T P++ +
Sbjct: 5421 NTAVTNVGTSGSGHKSQSS---VLADSETSKATPLMSTTSTL-GDTSVSTST-PNISQTN 5475
Query: 820 SGAHFLPVGQPLPTPLL-PQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLAS 878
Q PT L P+ S T + T FS +P ITQ T S
Sbjct: 5476 QI-------QTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVP---TGAITQASRTEIS 5525
Query: 879 SATTAA--------IPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQ 930
S+ T+ P +ST + ++L T V Q P S GI
Sbjct: 5526 SSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGI------ 5579
Query: 931 AAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGY 990
+P + L+QG S V+ HS + T TPG
Sbjct: 5580 ---LPWDTSTTLFQG---------------GTHSTVSQGFPHSEIT-----TLRSRTPGD 5616
Query: 991 FPTVVQPYVES-----NLLVPMGGVGGQVQVSQPGG-SLAQAPTTSSQQAVLESTQGVSQ 1044
+ P VE +L+ P V + P + P T+ +VL +T V
Sbjct: 5617 VSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLG 5676
Query: 1045 VAPAEPVAVAQTQATQPT--TLASSVDSAHSDVASGMSDGN---ENVPSSSGRHEGRTTK 1099
EPV + + PT L + D+AH++ N NV +S HE ++
Sbjct: 5677 TTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQS-- 5734
Query: 1100 RHYRKSVRSRSRHEKTSRP-----KLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGD 1154
SV + S K + P + +VS E +++T + + D
Sbjct: 5735 -----SVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGL-RDTR 5788
Query: 1155 NPEEIATIMVNNDFILAIERESFVDQVR-EIIEKADEMLSEDVSVEPEGDQGLESLQGKD 1213
EEI T+ + + + + + R E+I + +S + E++
Sbjct: 5789 TSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLS 5848
Query: 1214 DYGFSGSQKLEGEFKQPIPASSMPQ-QIGIPTSSLT--QVVHS-AGRRFIVSPVPESRLR 1269
+ F Q P ++ Q + + TSS + HS +RF S + R
Sbjct: 5849 TFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSR 5908
Query: 1270 ESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELR-------RAQMTEGPNTA 1322
+K + +V +++ S + L S SL A S + +T G
Sbjct: 5909 STKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKT 5968
Query: 1323 PPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSV--------IQSE 1374
P SS +G T+ A+ N T++ + S
Sbjct: 5969 IDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSS 6028
Query: 1375 VTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVP 1434
V++ ++ TG + + SP +V T P + S +L +
Sbjct: 6029 VSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMN 6088
Query: 1435 TST-SEIVVSSTALYPSVTVSATSA---------SAGGSTATPGPKPPAVVSQQAAGSTT 1484
++T S V SS +L + VS ++ ST +P P A S + T
Sbjct: 6089 STTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLT 6148
Query: 1485 VGATLTSVSTTTSFPSTASQLSIQLSSSTST-PTLAETVVVSAHSLDKTSHSSTTGLAFS 1543
+ +T +++T T PS + L QL+ TST T A T SA + D +T+ +
Sbjct: 6149 I-STHKTIATQTG-PSGVTSLG-QLTLDTSTIATSAGT--PSARTQDFVDSETTSVMNND 6203
Query: 1544 LSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPL 1603
L+ +S A ++ +S L PS + ST ST L V S+P
Sbjct: 6204 LNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTST------LQEHSTSSLVSVTSVP-- 6255
Query: 1604 VQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLF 1663
+A + + L +P T P+ +T + D T+ + +
Sbjct: 6256 TPTLAKITDMDTNL------------EPVTRSPQNLRNTLATSEATTDTHTMHPSINTAV 6303
Query: 1664 SEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVAL 1723
+ ++ + + TV+P + ++TST+ + T++P +
Sbjct: 6304 ANVGTTSSPNE---------FYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMK 6354
Query: 1724 PVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPG 1783
+ T + T+TS K G++ + TE+ L S G
Sbjct: 6355 KIESETTFSLIFRLRETSTS-QKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQG 6413
Query: 1784 PSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAG-TQPQKGVSQVKE 1842
+++P T+SP+ T T +V +S T AG T+ ++ +
Sbjct: 6414 -----TEKP----------TMSPD--TSTRSVTMLS-------TFAGLTKSEERTIATQT 6449
Query: 1843 GPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSE----DAKSVHFESSTSESSVLSSS 1898
GP ATS G + A G ++ + ++ + S TS SV +S
Sbjct: 6450 GPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTS 6509
Query: 1899 SPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRF 1958
S S L P IT P S VP + ++ S T PT G + T V
Sbjct: 6510 SSSSLLSLP---AITSP---SPVPTTLPESRPSSPVHLTSLPTS-GLVKTTDMLASVASL 6562
Query: 1959 --SVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEK------PELSEPSHLNGP 2010
++ T KI T ++ + AV EK P SEP + P
Sbjct: 6563 PPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSP 6622
Score = 71.2 bits (173), Expect = 1e-11
Identities = 341/1739 (19%), Positives = 599/1739 (34%), Gaps = 290/1739 (16%)
Query: 711 SSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATT 770
S +AQ S ++T +S+ + QT+PP T + + ++++ + T
Sbjct: 4060 SFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWT 4119
Query: 771 AQPVSQPQAPQVLPQVSAGKQLP--VSQPVPTIQGEPQIPVATQPSVVPVH---SGAHFL 825
P++ Q + + + P SQP P E ++ S+VP+H S ++ L
Sbjct: 4120 GTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEE----TSSSSSLVPIHATTSPSNIL 4175
Query: 826 PVGQ---PLPTPLLPQYPVSQIPISTPHVSTAQTGFS--------SLPITMAAGITQPLL 874
Q P TP PV+ + +S T S SLP +++ + L
Sbjct: 4176 LTSQGHSPSSTP-----PVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALS 4230
Query: 875 TLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANL------ 928
T +S T AI + + + + +P P + + I ++
Sbjct: 4231 TYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSV 4290
Query: 929 -GQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLAT 987
G + + + + QG R S +A S+ S I + V S T V T
Sbjct: 4291 FGSSETTEIETVSSVNQGLQER------STSQVASSATETSTVI-THVSSGDATTHVTKT 4343
Query: 988 PGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAP 1047
F + + Q + T S ++ + GV+
Sbjct: 4344 QATFSSGTS-------------ISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQ 4390
Query: 1048 AEPVAVAQT------QATQP----TTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRT 1097
P A +T P T LA + D S+ + +S G ++V +S T
Sbjct: 4391 TGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWTSPPSVAET 4450
Query: 1098 TKRHYRKSVR-----------SRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVT 1146
+ Y S+ S + + TS P + +V G L T +
Sbjct: 4451 S---YPSSLTPFLVTTIPPATSTLQGQHTSSP-VSATSVLTSGLVKTTDMLNTSMEPVTN 4506
Query: 1147 FKFDLDGDNPEEIATIMVNNDF----------ILAIERESFVDQVREIIEKADEMLSEDV 1196
+L+ + E +AT+ D + + S + + + E +
Sbjct: 4507 SPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSEPSTATS 4566
Query: 1197 SVEPEGDQGLE----SLQGKDDYGFSGS---------------QKLEGEFKQPIPASSMP 1237
+ P G S+ G + G Q++ + I S++
Sbjct: 4567 PMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNV- 4625
Query: 1238 QQIGIPTSSLTQVVHSAGRRFIVSP-----------VPESRLRESK--VFPSEITDTVAA 1284
+G T + V S FI +P V SRL S + +T T
Sbjct: 4626 -SVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTG 4684
Query: 1285 STAQSPGMNLSHSASSLSLQQAFSEL-----RRAQMTEGPNTAPPNFSHTGPTFPVVPPF 1339
S+ + + L+ S+L + +++T N + S T P F
Sbjct: 4685 SSGATSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASS 4744
Query: 1340 LSSIAGV-----PTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVT 1394
SS A V P++ A T +TSSP +S S + + V T V TS VT
Sbjct: 4745 PSSQAPVLVTTLPSSVAFTPQWHSTSSP---VSMSSVLTSSLVKTA---GKVDTSLETVT 4798
Query: 1395 SGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSL----------------------- 1431
S P S S L + S+T A I TT PS+
Sbjct: 4799 SS-----PQSMSNTLDDI--SVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAY 4851
Query: 1432 ---------QVPTSTSEIVVSSTALYPSVTVSATSASAGGSTA------------TPGPK 1470
V TST E S ++ S + T S T +
Sbjct: 4852 PEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSSTE 4911
Query: 1471 PPAVVSQQAAGSTT-VGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSL 1529
V ++ G+TT V T + S++TSFP Q ++ L ST T T T + S
Sbjct: 4912 TSTVPYKELTGATTEVSRTDVTSSSSTSFPG-PDQSTVSLDISTETNTRLSTSPIMTESA 4970
Query: 1530 DKT------SHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILP 1583
+ T H +T+ F++ S+++P AG+ S ++ G L + ++++ +P
Sbjct: 4971 EITITTQTGPHGATSQDTFTMD--PSNTTPQAGIHSAMTH--GFSQLDVTTLMSR---IP 5023
Query: 1584 QAAGPTSTPLLPQVPSIPP-LVQPVANVPAVQQTLIH----SQPQPALLPNQPHTHCPEV 1638
Q TS P + + S L P P++ + + S P +LL + +
Sbjct: 5024 QDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDIL 5083
Query: 1639 DSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVA 1698
+ +P + + + +K+ + + + S++ E + V + + A+A
Sbjct: 5084 RTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALA 5143
Query: 1699 PSK--------LLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTA 1750
S+ ++T+T P T++P+ + P TP TS + +
Sbjct: 5144 DSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSF 5203
Query: 1751 PSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRR-------T 1803
P+ + V P GT + P +S P + ++ R T
Sbjct: 5204 PTDTSFLLSKV-PTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKT 5262
Query: 1804 LSPEMITVTSAVGPVSMAAPTAITEAGTQPQKG-----VSQVKEGPVLATSSGAGVFKMG 1858
S EM T A P S + T + T +G V+Q + T G G +
Sbjct: 5263 KSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVS 5322
Query: 1859 RFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTL------VKPEPNGI 1912
+ + S S SSTS S+ SS P + L + G
Sbjct: 5323 WMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGT 5382
Query: 1913 TIP-GISSDVPESAHKTTASEAK-SDTGQPTKVGRFQVTTTANKVGRF-SVSKTEDKI-- 1967
T P ++S P + T A DT T VG S K++ +
Sbjct: 5383 TSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLA 5442
Query: 1968 -TDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDG 2026
++T K P+ S + L P +S+ + + ++P A+ LS + +
Sbjct: 5443 DSETSKATPLMS------TTSTLGDTSVSTSTPNISQTNQI---QTEPTAS-LSPRLRES 5492
Query: 2027 SGSPHSPHQLSSKS----LPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDK 2082
S S + + + +P+ ++Q+ +SS S SD++ + ++
Sbjct: 5493 STSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSI---SDLDRPTIAPDISTGMIT 5549
Query: 2083 HLKEIQDLQSRQKHEIESLYTKLGKVPPAVI-IPPAAPLSGRRRRPTKSKGSKSSRSSSL 2141
L + + + + T G ++ + L T S+G S ++L
Sbjct: 5550 RLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTL 5609
Query: 2142 GNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSD 2201
+++P G++S + PP SG + L+ P SP S +S
Sbjct: 5610 RSRTP---GDVSWMTT-----------PPVEETSSGFS-LMSPSMTSP------SPVSST 5648
Query: 2202 GAISVPSLSAPGQG------TSSTNTVGATVNSQAAQAQPPAM---TSSRKGTFTDDLH 2251
S+PS P ++TN +G T + + + PP + T R T+ D H
Sbjct: 5649 SPESIPSSPLPVTALLTSVLVTTTNVLG-TTSPEPVTSSPPNLSSPTQERLTTYKDTAH 5706
Score = 70.9 bits (172), Expect = 1e-11
Identities = 274/1389 (19%), Positives = 503/1389 (36%), Gaps = 234/1389 (16%)
Query: 656 DSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQ 715
D +SVF S + +TVS +Q Q ST +Q
Sbjct: 4283 DITSSTSVFGSSETTEIETVSSVNQGLQERST--------------------------SQ 4316
Query: 716 GQSQGQPSSSSLTGVSSSQPIQHPQQQQGI----QQTAPPQQTVQYSLSQTSTSSEATTA 771
S +S+ +T VSS H + Q + P Q + + + T S+ +T+
Sbjct: 4317 VASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTS 4376
Query: 772 QPVSQPQAPQVLPQ---VSAGKQLPVSQPVPTIQGEPQIPVATQPSVVP------VHSGA 822
+++ + Q A Q P T+ + P+A P + + G
Sbjct: 4377 LIMTESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGP 4436
Query: 823 HFLPVGQPLPTPLLPQYPVSQIPIST----PHVSTAQTGFSSLPITMAAGITQPLLTLAS 878
+ P P+ YP S P P ST Q +S P++ + +T L+
Sbjct: 4437 KDVSWTSP-PSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTD 4495
Query: 879 SATTAAIPGVSTV-----VPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAE 933
T+ P ++ +++ L T + + +HP + AV +MG
Sbjct: 4496 MLNTSMEPVTNSPQNLNNPSNEILATLAATTDIET-IHPS-INKAVTNMG---------- 4543
Query: 934 VPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSN----VASVCI--HSTVLSPPMPTEVLAT 987
SS VL+ P P S + P+S+ +AS+ I T PT L
Sbjct: 4544 -TASSAHVLHSTLPVSSEPS-TATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTA 4601
Query: 988 PGYFPTVVQPY---VESNLLVPMGGVGG-----QVQVSQPGGSLAQAPTTSSQQAVLEST 1039
+ +Q ESN+++ VG +++V + P S++ + S
Sbjct: 4602 GRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSV 4661
Query: 1040 QGVSQVAPAEPVAVA---QTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGR 1096
S+++ + P+ ++ T T + S + A S G +V + H
Sbjct: 4662 AS-SRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAHSKI 4720
Query: 1097 TTKRHYRKSVRSRSR---HEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDG 1153
TT + S++ ++ S P + + V + H+
Sbjct: 4721 TTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHST----------- 4769
Query: 1154 DNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLS---EDVSVEPEGDQGLESLQ 1210
+P +++++ ++ ++ VD E + + + +S +D+SV +E+
Sbjct: 4770 SSPVSMSSVLTSS----LVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTH 4825
Query: 1211 GKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRE 1270
+ + F+ S+ P+ + + ++T + I +P+S
Sbjct: 4826 PSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVT--TSTMEDTTISRSIPKS---- 4879
Query: 1271 SKVFPSEITDTVAASTAQSPGMNLSHSASSLS---------LQQAFSELRRAQMTEGPNT 1321
SK +E T+T ++ T + ++S +S + L A +E+ R +T +T
Sbjct: 4880 SKTTRTE-TETTSSLTPKLRETSISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSST 4938
Query: 1322 APPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEE 1381
+ P GP V I+ T +T+P+ S +E+T+ T+
Sbjct: 4939 SFP-----GPDQSTVS---LDISTETNTRLSTSPIMTES------------AEITITTQT 4978
Query: 1382 GIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVS-----ISTTSPSLQVPTS 1436
G G + P ++ S + + ++S +S TSP TS
Sbjct: 4979 GPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTS 5038
Query: 1437 TSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSV-STT 1495
+ +SS P++T + +S P + S + + L V S+
Sbjct: 5039 SPSSFLSS----PAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSL 5094
Query: 1496 TSFPSTASQLSIQLSSSTSTPTL-----AETVVVSAHSLDKTSHS----------STTGL 1540
+F ST+ ++ S T + E V A++ SHS +TT +
Sbjct: 5095 PNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQM 5154
Query: 1541 AFSLSA--PSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTP-LLPQV 1597
+ + P+ S+S SS + + + T +++ PT T LL +V
Sbjct: 5155 VITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKV 5214
Query: 1598 PSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEE 1657
P+ + V T ++S + + + T P+ + P+ IKT
Sbjct: 5215 PT--------GTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRV-FTSSIKTKSA 5265
Query: 1658 KLRSLFSEHSSSGAQHASVSLETSLVI-----ESTVTPGIPTTAV------APSKLLTST 1706
++ A H+++ L+TS + STVT G P + V P + T
Sbjct: 5266 EMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMT 5325
Query: 1707 TSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKP-PLTKAP--VLP 1763
T PP +L +P +T +PVS+T+ P + PS P P+T P VL
Sbjct: 5326 T----PPVEETSSVSSLMSSPAMTS---PSPVSSTS----PQSIPSSPLPVTALPTSVLV 5374
Query: 1764 VGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAP 1823
T++ T P P S ++P A + T E + +
Sbjct: 5375 TTTDVLGTTSPESVTSSPPNLSSITHERP-----ATYKDTAHTE--------AAMHHSTN 5421
Query: 1824 TAITEAGTQPQKGVSQ---------VKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGK 1874
TA+T GT SQ K P+++T+S +G VS + + +
Sbjct: 5422 TAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTS-----TLGDTSVSTSTPNISQTNQ 5476
Query: 1875 NKSEDAKSVH---FESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTAS 1931
++E S+ ESSTSE + SS++ +T P G +++ S+ +T+ S
Sbjct: 5477 IQTEPTASLSPRLRESSTSEKT--SSTTETNTAFSYVPTGAITQASRTEI--SSSRTSIS 5532
Query: 1932 EAKSDTGQP 1940
+ T P
Sbjct: 5533 DLDRPTIAP 5541
Score = 70.9 bits (172), Expect = 1e-11
Identities = 294/1457 (20%), Positives = 527/1457 (36%), Gaps = 266/1457 (18%)
Query: 603 IKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQG-- 660
I++ +S+ +P+ + TS VS+ + P+ PS+ + +D S +
Sbjct: 6796 IEKTSFSSSLMPSPAMTSPPVSSTL-PKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTT 6854
Query: 661 ------SSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA 714
SS E + + T + + H ST T ++ +T V S
Sbjct: 6855 SSPPNLSSTSHEILTTDEDTTAIEAMHP---STSTAATNVETTSSGHGSQSSVLADSEKT 6911
Query: 715 QGQSQGQPSSS-SLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLS----QTSTSSEAT 769
+ + +S+ T VS+S + +T ++ YSL+ +TS S A+
Sbjct: 6912 KATAPMDTTSTMGHTTVSTSMSVS--------SETTKIKRESTYSLTPGLRETSISQNAS 6963
Query: 770 TAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQ 829
+ S VL +V G VS+ T G IP +Q +V+P S + +
Sbjct: 6964 FSTDTSI-----VLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTR---TMTR 7015
Query: 830 PLPTPLLPQYPVSQIPIST-PHVSTAQTGFS-SLPITMAAGITQPLLTLA---SSATTAA 884
+P + + IP T P ST+Q + T + T LT S TT
Sbjct: 7016 LFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLM 7075
Query: 885 IPG---------VSTVVPSQLPTLLQ-PVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEV 934
G S PS LP+LL P T P + L + S +P
Sbjct: 7076 SRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPI-SSTLPVTISSSPLPVT-SLLTSS 7133
Query: 935 PLSSGDVLY------QGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATP 988
P+++ D+L+ PP+L + D + + ++ + P T
Sbjct: 7134 PVTTTDMLHTSPELVTSSPPKL--SHTSDERLTTGKDTT----NTEAVHPSTNT------ 7181
Query: 989 GYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAV-LESTQGVSQVAP 1047
SN+ +P G P +LA + T+ + + + STQ + VA
Sbjct: 7182 ----------AASNVEIPSSG------HESPSSALADSETSKATSPMFITSTQEDTTVAI 7225
Query: 1048 AEP--VAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKS 1105
+ P + ++ Q ++L+ + S V + S E S G TT+ R
Sbjct: 7226 STPHFLETSRIQKESISSLSPKLRETGSSVET--SSAIETSAVLSEVSIGATTEIS-RTE 7282
Query: 1106 VRSRSRHEKTSRPKLRILNVSNKGDRVVECQ----LETHNRKMVTFKFDLDGDNPEEIAT 1161
V S SR + + +L + ++++ L + + + G E T
Sbjct: 7283 VTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFT 7342
Query: 1162 IMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQ 1221
+ + L I + ++ + ++S GD S ++ SQ
Sbjct: 7343 LDTSTTPSLVITHSTMTQRLPH--SEITTLVSRGA-----GDVPRPSSLPVEETSPPSSQ 7395
Query: 1222 KLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDT 1281
P P SS +P SS HS+ S S L +V +E+ D
Sbjct: 7396 LSLSAMISPSPVSST-----LPASS-----HSS------SASVTSLLTPGQVKTTEVLDA 7439
Query: 1282 VAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLS 1341
A SP S S L+ + ++ + + PF +
Sbjct: 7440 SAEPETSSPPSLSSTSVEILATSEVTTDTEK-----------------------IHPFSN 7476
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ T+++ P++ P D T+ S + + G V+T T ++
Sbjct: 7477 TAVTKVGTSSSGHESPSSVLP--DSETTKATSAMGTISIMGDTSVSTLTPALS------- 7527
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAG 1461
+ + S SS+T + ++ SL +T V+S + + VS T A +
Sbjct: 7528 --NTRKIQSEPASSLTTRLRETSTSEETSLATEANT---VLSKVSTGATTEVSRTEAISF 7582
Query: 1462 GSTATPGPKPPAV--------VSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSST 1513
T+ GP+ + + + +A S + +++T T + + ++ L+++T
Sbjct: 7583 SRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTAT 7642
Query: 1514 STPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIP 1573
TP+ ET HS+ + P ++S G G PGG
Sbjct: 7643 -TPSWVET-----HSI----------VIQGFPHPEMTTSMGRG-------PGG------- 7672
Query: 1574 SVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQP----ALLPN 1629
V +P + P S+PL S+P + P P L H P P +LL +
Sbjct: 7673 -VSWPSPPFVKETSPPSSPL-----SLPAVTSP---HPVSTTFLAHIPPSPLPVTSLLTS 7723
Query: 1630 QPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSL----------- 1678
P T + + T+P + T + + + + + + A H S +
Sbjct: 7724 GPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSG 7783
Query: 1679 ---ETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPG-QV 1734
++S++ +S +P T+ + + +LTST P L + + +TPG +
Sbjct: 7784 YKSQSSVLADS--SPMCTTSTMGDTSVLTST------PAFLETRRIQTELASSLTPGLRE 7835
Query: 1735 STPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQ-----S 1789
S+ T+SG K T SK +P G + E + PGP+ + S
Sbjct: 7836 SSGSEGTSSGTKMSTVLSK--------VPTGA---TTEISKEDVTSIPGPAQSTISPDIS 7884
Query: 1790 QQPLEDLDAQLRRTLSPE--MITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLA 1847
+ + T S E M T TS +G + T T + T S + +G +
Sbjct: 7885 TRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQG--FS 7942
Query: 1848 TSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKP 1907
S + + + G VS + + K+ + S+ +T+ S +SS+ PES P
Sbjct: 7943 HSQMSTLMRRGPEDVSWMSPPLLE----KTRPSFSLMSSPATTSPSPVSSTLPESISSSP 7998
Query: 1908 EPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKI 1967
P ++S + KTT KS +P +++T+ + T +
Sbjct: 7999 LP-------VTSLLTSGLAKTTDMLHKS--SEPVTNSPANLSSTS-----VEILATSEVT 8044
Query: 1968 TDTKKEGPVASPPFMDL 1984
TDT+K P ++ D+
Sbjct: 8045 TDTEKTHPSSNRTVTDV 8061
Score = 68.2 bits (165), Expect = 9e-11
Identities = 318/1517 (20%), Positives = 533/1517 (35%), Gaps = 239/1517 (15%)
Query: 583 KQEESSLKQQVEQSSASQT-GIKQLPSASTGIPTASTTSAS-----------VSTQVEPE 630
K E+S+ Q++ S+ + T K+L A+T + TS+S VS + E
Sbjct: 4896 KLRETSISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTE 4955
Query: 631 EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAH----- 685
+ + I++ + FT S T G H
Sbjct: 4956 TNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMD--PSNTTPQAGIHSAMTHGFSQL 5013
Query: 686 STGTVPGHIPSTVQAQSQP--HGVYPPSSVAQGQSQGQPS--SSSLTGVSSSQPIQHPQQ 741
T+ IP V S P PSS + PS SS+L S P+
Sbjct: 5014 DVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLT 5073
Query: 742 QQGIQQT---APPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVS--- 795
++ T + V SL S++S+ A ++ P ++ + +
Sbjct: 5074 SGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNS 5133
Query: 796 --QPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQI--------- 844
+ + + P AT V+ VG P P+ +P + S+
Sbjct: 5134 GHESHSPALADSETPKATTQMVITT-------TVGDPAPSTSMPVHGSSETTNIKREPTY 5186
Query: 845 -------PISTPHVSTAQTGFSSLPITMAAG-ITQPLLTLASSATTAAIP--GVSTVVPS 894
ST S+ T S L + G IT+ T +S++ + P STV P
Sbjct: 5187 FLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPD 5246
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVL---------YQG 945
+ V S + + + + + P + +PL + L QG
Sbjct: 5247 TFTGEIPRV--FTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQG 5304
Query: 946 FP----PRLPPQYPGDSNIAPSSNVASVCIHSTVLSPP---MPTEVLAT-PGYFPTVVQP 997
FP L PG+ + + V S+++S P P+ V +T P P+ P
Sbjct: 5305 FPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLP 5364
Query: 998 Y--VESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQ 1055
+ +++LV V G T+S ++V S +S + P
Sbjct: 5365 VTALPTSVLVTTTDVLG----------------TTSPESVTSSPPNLSSITHERPATYKD 5408
Query: 1056 TQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSR--SRHE 1113
T T+ A+ S ++ V + + G+ + SS + T+K S S
Sbjct: 5409 TAHTE----AAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSV 5464
Query: 1114 KTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIE 1173
TS P + N Q++T ++ + + + +T N F +
Sbjct: 5465 STSTPNISQTN-----------QIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSY-VP 5512
Query: 1174 RESFVDQVREIIEKADEMLS--EDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPI 1231
+ R I + +S + ++ P+ G+ + F PI
Sbjct: 5513 TGAITQASRTEISSSRTSISDLDRPTIAPDISTGM----------------ITRLFTSPI 5556
Query: 1232 PASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPES--------RLRESKVFP-SEITDTV 1282
S ++ + T + T S G + P S S+ FP SEIT
Sbjct: 5557 MTKS--AEMTVTTQTTTPGATSQG----ILPWDTSTTLFQGGTHSTVSQGFPHSEITTLR 5610
Query: 1283 AASTAQSPGMN---LSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPF 1339
+ + M + ++S SL + P + P + PV
Sbjct: 5611 SRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSS------PLPVTALL 5664
Query: 1340 LSSIAGVPTTAAATAPVPATSSPPNDISTS---VIQSEVTVPTEEGIAGVATSTGVVTSG 1396
S + T+P P TSSPPN S + + + T TE A + T+T V G
Sbjct: 5665 TSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVG 5724
Query: 1397 GLPIPPVSESPV-LSSVVSSITIPAVV-------SISTTSPSLQVPTSTSEIVVSSTALY 1448
S+S V S S T P + S+ST++P+ +E S+++L
Sbjct: 5725 TSISGHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTE---STSSLI 5781
Query: 1449 PSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTT-VGAT--LTSVSTTTSFPSTASQL 1505
P + + TS T T V+S+ +TT V T +TS TT S P S++
Sbjct: 5782 PGLRDTRTSEEINTVTET-----STVLSEVPTTTTTEVSRTEVITSSRTTISGPD-HSKM 5835
Query: 1506 SIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGL--AFSLSAPSSSSSPGAGVSSYISQ 1563
S +S+ T T V + + T+ + G +L+ +SS++ G S ++Q
Sbjct: 5836 SPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQ 5895
Query: 1564 PGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQ 1623
P +T + G + PS+ P + VP T HS
Sbjct: 5896 R-------FPHSEETTTMSRSTKGVS----WQSPPSVEETSSPSSPVPLPAIT-SHSSLY 5943
Query: 1624 PALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKL-RSLFSEHSSSG---AQHASVSLE 1679
A+ + P + P T + ID + T E + SL S S SG AS + E
Sbjct: 5944 SAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTE 6003
Query: 1680 TSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVS 1739
T E+T + TT + KL +S + P + P + + STP S
Sbjct: 6004 TIHFSENTAETNMGTTN-SMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIV--STSTPGS 6060
Query: 1740 TTTSGV-KPGTAPSKPPL------------TKAPVLPVGTELPAGTLPSEQLPPFPGPS- 1785
T V + T+P P L T++ + L A T S + P+
Sbjct: 6061 PETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTF 6120
Query: 1786 LTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAA-PTAITEAGTQPQKGVSQVK-EG 1843
+ S Q + D +SPE + S P++++ T T+ G + Q+ +
Sbjct: 6121 MPASAQSTKSPD------ISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDT 6174
Query: 1844 PVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPEST 1903
+ATS+G R Q V ++ + ++ K+ F S E++ LSS +P
Sbjct: 6175 STIATSAGT---PSARTQDFVDSETTSVMNNDLNDVLKTSPF--SAEEANSLSSQAPLLV 6229
Query: 1904 LVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRF----- 1958
P P ++S + E H T++ + + PT + T V R
Sbjct: 6230 TTSPSP-------VTSTLQE--HSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLR 6280
Query: 1959 SVSKTEDKITDTKKEGP 1975
+ T + TDT P
Sbjct: 6281 NTLATSEATTDTHTMHP 6297
Score = 67.0 bits (162), Expect = 2e-10
Identities = 249/1147 (21%), Positives = 421/1147 (36%), Gaps = 194/1147 (16%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
P P++SMP + SS T + F+ + E+ + FP TDT +
Sbjct: 5163 PAPSTSMP----VHGSSETTNIKREPTYFLTPRLRETSTSQESSFP---TDTSFLLSKVP 5215
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSI----AG 1345
G S++ ++ S + T P+T T + F SSI A
Sbjct: 5216 TGTITEVSSTGVNSSSKISTPDHDKSTVPPDTF---------TGEIPRVFTSSIKTKSAE 5266
Query: 1346 VPTTAAATAPVPATSSP-PNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGG----LPI 1400
+ T A+ P A+ S P D ST++ Q +G +T + G +
Sbjct: 5267 MTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTT 5326
Query: 1401 PPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASA 1460
PPV E+ +SS++SS + + +S+TSP +P+S + TAL SV V+ T
Sbjct: 5327 PPVEETSSVSSLMSSPAMTSPSPVSSTSPQ-SIPSSPLPV----TALPTSVLVTTTDVLG 5381
Query: 1461 GGSTATPGPKPPAVVS--------------QQAAGSTTVGATLTSVSTTTSFPSTASQLS 1506
S + PP + S +AA + +T+V T+ S + S +
Sbjct: 5382 TTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVL 5441
Query: 1507 IQLSSSTSTPTLAET-------VVVSAHSLDKTSHSSTTGLAF--------SLSAPSSSS 1551
+S +TP ++ T V S ++ +T+ T A S S +SS+
Sbjct: 5442 ADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSST 5501
Query: 1552 SPGAGVSSYISQPGGLHPLVIPSVIASTPIL------PQAAGPTSTPLLPQVPSIPPLVQ 1605
+ SY+ P G + I+S+ P A ST ++ ++ + P++
Sbjct: 5502 TETNTAFSYV--PTGAITQASRTEISSSRTSISDLDRPTIAPDISTGMITRLFT-SPIMT 5558
Query: 1606 PVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDS-DTQPKAPGIDDIKTLEEKLRSLFS 1664
A + QT +LP T + + T + +I TL + S
Sbjct: 5559 KSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVS 5618
Query: 1665 -------EHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLP 1717
E +SSG S S+ + + ST IP++ + + LLTS T T
Sbjct: 5619 WMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVT----TTNV 5674
Query: 1718 LGTVALPVTPVVTPGQVSTPVS---TTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLP 1774
LGT + P +P +S+P TT A T V VGT +
Sbjct: 5675 LGTTS-PEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHE-- 5731
Query: 1775 SEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPT-AITEAGTQP 1833
+QS P D+ + SP + +T A+G S++ T A E Q
Sbjct: 5732 ------------SQSSVP---ADSHTSKATSP--MGITFAMGDTSVSTSTPAFFETRIQT 5774
Query: 1834 QKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSE-- 1891
+ S + P L + + S + + SE + E S +E
Sbjct: 5775 ESTSSLI---PGLRDT-----------RTSEEINTVTETSTVLSEVPTTTTTEVSRTEVI 5820
Query: 1892 -SSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTT 1950
SS + S P+ + + P + TI +S + T S + T Q +G T
Sbjct: 5821 TSSRTTISGPDHSKMSPYISTETITRLS-----TFPFVTGSTEMAITNQTGPIGTISQAT 5875
Query: 1951 -------TANKVG-------RFSVSKTEDKITDTKKEGPVASPPFMD-----LEQAVLPA 1991
TA+ G RF S+ ++ + K SPP ++ LPA
Sbjct: 5876 LTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPA 5935
Query: 1992 VIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLS 2051
+ S S + S+ P + L+ + +L + SLPS + S S
Sbjct: 5936 I--TSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPS---ASSFS 5990
Query: 2052 NSFNSSYMSSDNES-DIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTK-LGKVP 2109
+S S++ E+ + + + H + H S++++ G P
Sbjct: 5991 GEILTSEASTNTETIHFSENTAETNMGTTNSMH----------KLHSSVSIHSQPSGHTP 6040
Query: 2110 PAV--------IIPPAAPLSGRRRRPTKSKGS------KSSRSSSLGN---KSPQLSGNL 2152
P V I+ + P S + + S K ++ + N +S + ++
Sbjct: 6041 PKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSV 6100
Query: 2153 SGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYS----------AFTSDG 2202
S +A V + T + P +P S Q+ + P SS + S T G
Sbjct: 6101 SLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTG 6160
Query: 2203 AISVPSLSAPGQGTSSTNTVGATVNSQAAQAQP--PAMTSSRKGTFTDDLHKLVDNWARD 2260
V SL GQ T T+T+ + + +A+ Q + T+S +D+ K A +
Sbjct: 6161 PSGVTSL---GQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEE 6217
Query: 2261 AMNLSGR 2267
A +LS +
Sbjct: 6218 ANSLSSQ 6224
Score = 65.5 bits (158), Expect = 6e-10
Identities = 237/1170 (20%), Positives = 401/1170 (34%), Gaps = 218/1170 (18%)
Query: 1276 SEITDTVAASTAQSPGMNL---SHSASSLSLQQA----FSELRRAQMTEGPNTAPPNFSH 1328
SE+ T + S S G L SH + ++ Q F++ Q T P T+P
Sbjct: 918 SELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPR--FK 975
Query: 1329 TGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDI--STSVIQSEVTVPTEE----- 1381
TG +P ++++ T+ +AT V +SP +TS+ + T+ T E
Sbjct: 976 TG-----LPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGP 1030
Query: 1382 GIAGVATST-----GVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSIS-TTSPSLQV-- 1433
G VA++ G +T G L + SS S A S+S + SPS +
Sbjct: 1031 GSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDA 1090
Query: 1434 -----PTSTSEIVVS--------------------STALYPSVTV---------SATSAS 1459
P TS+ V + S+AL P +T SA S
Sbjct: 1091 AGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTW 1150
Query: 1460 AGGSTATPGPKPPAVV------SQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSST 1513
G +++P P V +Q+ S + TS + PST S + +S
Sbjct: 1151 LGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSG 1210
Query: 1514 S----------TPTLAETVVVSAHSLD--KTSHSSTTGLAFSLSAPSSSSSPGAGVSSYI 1561
+ TP+ A ++ S L T ST + L A +SS SP +
Sbjct: 1211 AIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMA 1270
Query: 1562 S--QPGGLHPLVIPSVIA----STPILPQAAGPTSTPLLPQVPSIPPLVQPVANVP---- 1611
S +PG PL PS+ ST + ++G + P + P +
Sbjct: 1271 SVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDP 1330
Query: 1612 ----AVQQTLIHSQPQPALLPNQPHTHC--PEVDSDTQPKAPGIDDIKTLEEKLRSLFSE 1665
+ Q + HS N P T P S + PK ++ + K ++
Sbjct: 1331 KDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGS-PKISSSPNLTSPATKAWTITDT 1389
Query: 1666 HSSSGAQHASVSLETSLVIESTVTPG-----IPTTAVAPSKLLTSTTSTCLPPTNLPLG- 1719
S H + E S E+ PG IPT+ S L T+ P L
Sbjct: 1390 TEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSE 1449
Query: 1720 --TVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQ 1777
T+ LP+ ++ ST ++PS P T A P+ T PS +
Sbjct: 1450 QTTITLPMATWLSTSLTEEMASTDLDI----SSPSSPMSTFAIFPPMST-------PSHE 1498
Query: 1778 LPPFPGPSLTQSQQPLEDLDAQLR-RTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKG 1836
L + LD L R+L T + P++ T++ E TQ Q
Sbjct: 1499 LSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTW-TSVIEHSTQAQDT 1557
Query: 1837 VSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQK-----------EGKNKSE------- 1878
+S AT S V + + Q S+ A + +G++ SE
Sbjct: 1558 LS--------ATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKP 1609
Query: 1879 DAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIP----GISSDVPESAHKTTASEAK 1934
++ E T +++ S+ ++T +G+T+ I + P A E +
Sbjct: 1610 STDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERR 1669
Query: 1935 SDTGQPTKVGRFQVTTTA-------NKVGRFSV---SKTEDKITDTKK--------EGPV 1976
S T + G + T+ +GR S T + +TD+ K +G
Sbjct: 1670 SSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNT 1729
Query: 1977 ASPPFMD---LEQAVLPAVIPKKEKPELSEPSHLNGPS--SDPEAAFLSRDVDDGSGSPH 2031
A ++ E + + IP P + + G + + ++ D+ S
Sbjct: 1730 ALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTE 1789
Query: 2032 SPH-------------------QLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIED--- 2069
S + +S LPS S ++ + + ++ N +D D
Sbjct: 1790 SSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSH 1849
Query: 2070 -----------EDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAA 2118
D L R L+ D S+ S +T + + +
Sbjct: 1850 GVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIH 1909
Query: 2119 PLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQ 2178
P R T + G++++ +S+ GN++ L+ S V+ T P N
Sbjct: 1910 P-----RPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTH 1964
Query: 2179 NQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGA--------TVNSQA 2230
+ + P S+ + + A+S +S Q T N+V +V+S +
Sbjct: 1965 SPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGS 2024
Query: 2231 AQAQPPAMTSSRKGTFTDDLHKLVDNWARD 2260
+ + P + S T + +W D
Sbjct: 2025 STSSPYSSASLESLDSTISRRNAITSWLWD 2054
Score = 64.7 bits (156), Expect = 1e-09
Identities = 312/1538 (20%), Positives = 548/1538 (35%), Gaps = 260/1538 (16%)
Query: 586 ESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQP 645
+S+L + + + T LP+ + T + AS ++ + PE + ++
Sbjct: 2887 QSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTK 2946
Query: 646 SISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPH 705
+IS S S+ FTE+ S + S + ++GT G ++ S P
Sbjct: 2947 AISA-------SSFQSTGFTETPEGS-ASPSMAGHEPRVPTSGT--GDPRYASESMSYP- 2995
Query: 706 GVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTS 765
PS + + +S T S+ Q + I + ++ + STS
Sbjct: 2996 ---DPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLST--EKETSFLSPTASTS 3050
Query: 766 SEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFL 825
+ + S + P +L + L +S + + P T + G
Sbjct: 3051 RKTSLFLGPSMARQPNILVHLQT-SALTLSPTSTLNMSQEEPPELTSSQTIAEEEGT--- 3106
Query: 826 PVGQPLPTPLLP-QYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAA 884
+ P + P S +P+S+P TA+ S P T A+ I+ P T T
Sbjct: 3107 -TAETQTLTFTPSETPTSLLPVSSPTEPTARR--KSSPETWASSISVPAKTSLVETTDGT 3163
Query: 885 IPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQ 944
+ V+T+ S Q + P+ PA S G P +S+ +
Sbjct: 3164 L--VTTIKMSS--QAAQGNSTWPAPAEETGSSPAGTSPGSP---------EMSTTLKIMS 3210
Query: 945 GFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPY-VESNL 1003
P + P+ I STV + P T P T V+P ++S
Sbjct: 3211 SKEPSISPE-----------------IRSTVRNSPWKTPETTVP--METTVEPVTLQSTA 3251
Query: 1004 LVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAE---------PVAVA 1054
L G G P G+ +PT S + +L + + +P E P
Sbjct: 3252 L----GSGSTSISHLPTGT--TSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTPGGTR 3305
Query: 1055 QTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRH--------EGRTTKRHYRKSV 1106
Q+ AT + S +A S +G E V ++G G T H S
Sbjct: 3306 QSLATMSSVSLES-PTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLST 3364
Query: 1107 RSRSRHEKTSRPKLRILNVSNKGDRVVECQLETH-------NRKMVTFKFDLDGDNPEEI 1159
S + + P + ++++K E + T N K++ + E
Sbjct: 3365 SSNILEDPVTSPN-SVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAY 3423
Query: 1160 ATIMVNNDFILA--IERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQ----GKD 1213
++ +D I + D + + + VS+ P GDQG+ SL GK
Sbjct: 3424 SSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSL-PSGDQGITSLTNPSGGKT 3482
Query: 1214 DYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFI-VSPVPESRLRESK 1272
S + G S++ I L+Q A + V+ P + S
Sbjct: 3483 SSASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGI--ST 3540
Query: 1273 VFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNT-----APPNFS 1327
+ T+++ ++T +P + +S S+ + + RR TE P+T A +++
Sbjct: 3541 TITTMGTNSI-STTTPNPEVGMSTMDSTPATE------RRTTSTEHPSTWSSTAASDSWT 3593
Query: 1328 HTGPTFPV-VPPFLSSIAGVPTTA--AATAPVPATSSPPNDISTSVIQSEVTVPTEEGIA 1384
T T + V +I+ + TT+ A++ + + S+P I +VI + + P+ + A
Sbjct: 3594 VTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRI--TVIGTSLVTPSSDASA 3651
Query: 1385 GVATSTGVVTSGGLPIPPVSESPV--LSSVV-SSITIPAVVSISTTSPSLQVPTSTSEIV 1441
V T T P + +P+ S V SI++P ++S S T P+ST
Sbjct: 3652 -VKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWT------PSSTEA-- 3702
Query: 1442 VSSTALYPSVTVSATSASAGGSTATPG-PKPPAVVSQQAAGSTTVGATLTSVSTTTSFP- 1499
V VS S + P P + + G +L+S + TTS P
Sbjct: 3703 -------EDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQ 3755
Query: 1500 --STASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGV 1557
+T +L+++ S +T L ++ ++ + + ++G+ F S P +S
Sbjct: 3756 GATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTF--SRPDPTSKKAEQT 3813
Query: 1558 SSYISQPGGLHPLVIPSVIAST-PILPQAA----------GPT----------------- 1589
S+ + HP +P A+T ++P A G T
Sbjct: 3814 STQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKE 3873
Query: 1590 -STPLLPQVPSI-----PPLVQPVANVPAVQQTL----IHSQPQPALLP---NQPHTHCP 1636
STP P + + ++ V + +V +TL I+ + P + P+
Sbjct: 3874 KSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSPYERIA 3933
Query: 1637 EVDSDTQPKA--PGIDDIKTLEEKLRSLFSEHSSSGAQHASVSL----------ETSLVI 1684
+S T +A P + ++T S + HS+ A AS L E ++V
Sbjct: 3934 PSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVS 3993
Query: 1685 ESTVT-PGIPTTAVAPSKLLT-------------STTSTCLPPTNLPLGTVALPVTPVVT 1730
ST T P P+ LT STT T + + P T + +
Sbjct: 3994 MSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITS 4053
Query: 1731 PGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQ 1790
++S+ S ++ +PS+ +T+ P TE G + + Q P P T
Sbjct: 4054 SKRISS--SFLAQSMRSSDSPSE-AITRLSNFPAMTE-SGGMILAMQTSP---PGATSLS 4106
Query: 1791 QPLEDLDAQLRRTLSP----------EMITVTSAVGP--VSMAAPTAITE---------- 1828
P D A T +P E T+ S GP S +P ++ E
Sbjct: 4107 APTLDTSATASWTGTPLATTQRFTYSEKTTLFSK-GPEDTSQPSPPSVEETSSSSSLVPI 4165
Query: 1829 -AGTQP------QKGVSQVKEGPV----LATSSGAG-VFKMGRFQVSVAAD--------- 1867
A T P +G S PV L+ +SG G M R +
Sbjct: 4166 HATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTA 4225
Query: 1868 GAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLV-KPEPNGITIPGISSDVPESAH 1926
G S D K++H + T+ +++ ++SS S + +P+ T P ++S +
Sbjct: 4226 GEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDIT 4285
Query: 1927 KTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTE 1964
+T+ S+T + V + + S TE
Sbjct: 4286 SSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATE 4323
Score = 63.2 bits (152), Expect = 3e-09
Identities = 290/1359 (21%), Positives = 482/1359 (35%), Gaps = 207/1359 (15%)
Query: 662 SVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQS--Q 719
S F E S +T+S HE +PG S+ + ++P G P ++ + ++
Sbjct: 2264 SHFPEKTTHSFRTIS-SLTHELTSRVTPIPGDWMSSAMS-TKPTGASPSITLGERRTITS 2321
Query: 720 GQPSSSSLTGVSS-------SQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQ 772
P++S + +S S + + I + S S + + + +
Sbjct: 2322 AAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASS 2381
Query: 773 PVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPV-------ATQPSVVPVHSGAHFL 825
+ + + P +G S P PQ+P AT PSV S + L
Sbjct: 2382 TMDVTKTASISPTSISGMTAS-SSPSLFSSDRPQVPTSTTETNTATSPSV---SSNTYSL 2437
Query: 826 PVGQPLP-TP-LLPQYPVSQIPISTPHVSTAQTG----FSSLPITMAAGITQPLLTLASS 879
G + TP LP + ++ P+ T A + FS++ T A P + S
Sbjct: 2438 DGGSNVGGTPSTLPPFTITH-PVETSSALLAWSRPVRTFSTMVSTDTASGENPTSS-NSV 2495
Query: 880 ATTAAIPGVSTVVPS--QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLS 937
T+ PG T V S LP + T + H L + +L A S
Sbjct: 2496 VTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSS 2555
Query: 938 SGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPT-----EVLATPGYFP 992
+ ++++ +S S IHS+ +P PT E ATP
Sbjct: 2556 A----------------TSEASLLTTSE--SKAIHSSPQTPTTPTSGANWETSATPESLL 2597
Query: 993 TVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVA 1052
V + L V + S ++ P+T + T + PA P+
Sbjct: 2598 VVTE--TSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPT--LLPDTPAIPLT 2653
Query: 1053 VAQTQATQPTT-LASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSR 1111
AT+PT+ LA+S DS + + + SD VP TT S
Sbjct: 2654 -----ATEPTSSLATSFDS--TPLVTIASDSLGTVPE--------TTLTMSETSNGDALV 2698
Query: 1112 HEKTSRPKLRILNVSNKGDRVVECQLE---THNRKMVTFK-FDLDGDNPEEIATIMVNND 1167
+ S P I ++ +G V E L T K+V + +G ++T+
Sbjct: 2699 LKTVSNPDRSIPGITIQG--VTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTT 2756
Query: 1168 FILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEG-E 1226
L + S + +++ + + V G QG+ S G SGS G +
Sbjct: 2757 GSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIR----SGSTHSTGTK 2812
Query: 1227 FKQPIPASSMPQQIG----IPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTV 1282
+P + P ++ I T+ LT +A + V P
Sbjct: 2813 TFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKP-------------------- 2852
Query: 1283 AASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSS 1342
T+ G+ SASS S +AF+ L A T G + F F VP +
Sbjct: 2853 ---TSAESGLLTPVSASS-SPSKAFASLTTAPPTWGIPQSTLTFE-----FSEVPSLDTK 2903
Query: 1343 IAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPP 1402
A +PT + +P S + S+S+ +S P + A + TST +++
Sbjct: 2904 SASLPTPGQSLNTIP--DSDASTASSSLSKS----PEKNPRARMMTSTKAISASSFQSTG 2957
Query: 1403 VSESPVLSSVVSSITIPAVVSISTT------SPSLQVPT-STSEIVVSSTALYPSVTV-- 1453
+E+P S+ S V S T S S+ P S + ++ST+L +T
Sbjct: 2958 FTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLF 3017
Query: 1454 SATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSF---PSTASQLSIQLS 1510
S A+ GS+++P +S T+ + S S TS PS A Q +I +
Sbjct: 3018 STGQAARSGSSSSP-------ISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVH 3070
Query: 1511 SSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPL 1570
TS TL+ T ++ + +S+ +A A + P
Sbjct: 3071 LQTSALTLSPTSTLNMSQEEPPELTSSQTIA-------EEEGTTAETQTLTFTPSETPTS 3123
Query: 1571 VIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQ 1630
++P S+P P A +S S+P V T I Q A +
Sbjct: 3124 LLP---VSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNST 3180
Query: 1631 PHTHCPEVDSDTQPKAPGIDDIKT----LEEKLRSLFSEHSSSGAQHASVSLETSLVIES 1686
E S +PG ++ T + K S+ E S+ + ET++ +E+
Sbjct: 3181 WPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMET 3240
Query: 1687 TVTP------GIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVST 1740
TV P + + + + S L T TTS PT L T + ++P +P + T + +
Sbjct: 3241 TVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSP--SPPEAWTNLYS 3298
Query: 1741 TTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQL 1800
T G GT T+ S L S+T + Q
Sbjct: 3299 GTPG--------------------GTRQSLATMSSVSLESPTARSITGTGQ--------- 3329
Query: 1801 RRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGV-SQVKEGPVLATSSGAGVFKMGR 1859
SPE+++ T+ + T T T S + E PV + +S + + +
Sbjct: 3330 --QSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKSK 3387
Query: 1860 FQVS--VAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGI 1917
+ V+ N K + E TS S + SS S + + IT+ G
Sbjct: 3388 HKTETWVSTTAIPSTVLNN----KIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITL-GA 3442
Query: 1918 SSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVG 1956
S DV + + T+ ++ S P+ G +T+ N G
Sbjct: 3443 SPDVTNTLYITSTAQTTSLVSLPS--GDQGITSLTNPSG 3479
Score = 60.1 bits (144), Expect = 3e-08
Identities = 152/672 (22%), Positives = 230/672 (34%), Gaps = 103/672 (15%)
Query: 1353 TAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSV 1412
T+P T PP STSV A + TS V SG + S +
Sbjct: 539 TSPSMKTERPP--ASTSVA------------APITTSVPSVVSGFTTLKTSSTKGIWLEE 584
Query: 1413 VSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTA------- 1465
S+ T+ + T+ VPT S SST T T A+A T+
Sbjct: 585 TSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLAT 644
Query: 1466 --TPGPKPPAVVSQQAAGSTTVGATLTSVSTTTS-FPSTASQLSIQLSSSTSTPTLAETV 1522
P PA VS+ AAGS+ G T S + +S P T+ S+Q S+ +L T
Sbjct: 645 NGVPVSVSPA-VSKTAAGSSPPGGTKPSYTMVSSVIPETS---SLQSSAFREGTSLGLTP 700
Query: 1523 VVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGL-HPLVIPSVIASTPI 1581
+ + H S S S P SS+ + + +S H S+ TP
Sbjct: 701 LNTRHPFSSPEPDSAGHTKISTSIPLLSSA--SVLEDKVSATSTFSHHKATSSITTGTPE 758
Query: 1582 LPQAAGPTSTPL----LPQVPSIPPLVQ----------PVANVPAVQQTLIHSQPQPALL 1627
+ P+S L L + P V+ P A + + +
Sbjct: 759 ISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDS 818
Query: 1628 PNQPHTHCPEVDSDTQPKA---PGIDDIKTL----EEKLRSLFSEHSSSGAQHASVS--- 1677
PN T +S P P + +KT S + + SVS
Sbjct: 819 PNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPE 878
Query: 1678 -----LETSLVIESTVTPGIPTTAVAP-------------------SKLLTSTTSTCLPP 1713
+ T+L S TP PT P S +T++T + LP
Sbjct: 879 TSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPK 938
Query: 1714 TNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTL 1773
+ GT + T T + P STT P P T V T L A +
Sbjct: 939 ISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSAT-TTVSTSATSLSATVM 997
Query: 1774 PSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAG--- 1830
S+ F P+ + ++A R S ++T + GP SMA + G
Sbjct: 998 VSK----FTSPATS-------SMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGY 1046
Query: 1831 -TQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQK-EGKNKSEDAKSVHFESS 1888
T+ + S + G A+S + F M + VS++ +Q + S ++ F +
Sbjct: 1047 ITEGRLDTSHLPIG-TTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDT 1105
Query: 1889 TSESSVLSSSSPESTLVKPEPNGITIPGIS-----SDVPESAHKTTASEAKSDTGQPTKV 1943
S+ V +S E T+ + + P ++ S P SA T S PT
Sbjct: 1106 FSD-DVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPK 1164
Query: 1944 GRFQVTTTANKV 1955
T + +V
Sbjct: 1165 VTMSSTFSTQRV 1176
Score = 59.3 bits (142), Expect = 4e-08
Identities = 219/1079 (20%), Positives = 373/1079 (34%), Gaps = 110/1079 (10%)
Query: 1356 VPATSSPPNDISTSVIQSEVTVPTEEGIAGVA----TSTGVVTSGGLPIPPVSESPVLSS 1411
+P +SSP + T ++ T + G+ G TSTG + +P S L+S
Sbjct: 7 LPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTSPDKTLAS 66
Query: 1412 VVSSITIPAVVSISTTSPSLQVPTS---TSEIVVSSTALYPSVTVSATSASAGGSTATPG 1468
SS+ S+ S +L TS T +S +L P V + + S +
Sbjct: 67 PTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGL 126
Query: 1469 PKPPAVVSQQAAGSTTVGATLTSVSTTTSFPST-----ASQLSIQLSSSTSTPTLAETVV 1523
P S T +T T TTS P T ++ S ST TP +
Sbjct: 127 SSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIP 186
Query: 1524 VSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHP----LVIPSVIAST 1579
V S KT ST A +AP S +P + PG +P L + S
Sbjct: 187 VKITSPMKTFADST---ASKENAP-VSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSP 242
Query: 1580 PILPQAAGPTSTPLLPQVPSIP-PLVQPVANVPAVQQTLIHSQPQPALLPNQ-PHTHCPE 1637
P + G TS L+ P +P + + T ++L N+ T
Sbjct: 243 KGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFS 302
Query: 1638 VDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAV 1697
S T P +PG+ + + ++ + S A+ ++ + ++ I S TP I T
Sbjct: 303 GQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRST--ISSLGTPSISTKQT 360
Query: 1698 APSKLL--TSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPP 1755
A + L + +P T++ + + T G ST TTTS T S+
Sbjct: 361 AETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTS--PSTTLVSEET 418
Query: 1756 LTKAPVLPVGTE--LPAGTLPSEQLPPFPGPSLTQSQQP---LEDLDAQLRRTLSPEMIT 1810
T TE L P E P +T + P LD+++R SP ++
Sbjct: 419 NTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIR---SPSQVS 475
Query: 1811 VTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQ 1870
+ + T+ ++ + G S + +TS + Q ++
Sbjct: 476 SSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQ--QFSEPQH 533
Query: 1871 KEGKNKSEDAKSVHFESSTSESSVLSSSSPE-----STLVKPEPNGITIPGISSD--VPE 1923
+ S K+ +STS ++ +++S P +TL GI + S+D + E
Sbjct: 534 TQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGE 593
Query: 1924 SAHKTTASEAKSDTGQPTKVG---RFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPP 1980
S T + TG G R TT + S+T +T PV+ P
Sbjct: 594 STAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSP 653
Query: 1981 FMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKS 2040
+ + + P KP + S + +S +++ G ++ H SS
Sbjct: 654 --AVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPE 711
Query: 2041 LPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIES 2100
S ++S + S +ED ++ + H+ S
Sbjct: 712 PDSAG-----HTKISTSIPLLSSASVLED----------------KVSATSTFSHHKATS 750
Query: 2101 LYTK-----LGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSP---QLSGNL 2152
T K P+ + + LS P + + + +S L + SP + +G++
Sbjct: 751 SITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNA----TSPLTHPSPSGEETAGSV 806
Query: 2153 SGQSAASVLHPQQTLHPPGNI-PESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSA 2211
S ++ +HP G + ES ++ L PS + + F+S S PS
Sbjct: 807 LTLSTSAETTDSPNIHPTGTLTSESSESPSTLSL---PSVSGVKTTFSS----STPSTHL 859
Query: 2212 PGQGTSSTNTVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRR--- 2268
G + T +V SQ + T+ + + +D W + S
Sbjct: 860 FTSGEETEETSNPSV-SQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVS 918
Query: 2269 -----GSKGHMNYEGPGMARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPP 2323
S N G + + G +S T+ + + S T P
Sbjct: 919 ELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTT-----WPETSPR 973
Query: 2324 QQYGFPATPFGAQWSGTGGPAPQPLGQFQPVGTASLQNFNISN-----LQKSISNPPGS 2377
+ G P+ S T A + +F T+S++ +I L +N PGS
Sbjct: 974 FKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGS 1032
Score = 58.5 bits (140), Expect = 7e-08
Identities = 309/1530 (20%), Positives = 529/1530 (34%), Gaps = 252/1530 (16%)
Query: 615 TASTTSASVSTQVEPEEPEADQHQQLQYQQPSISV-LSDGTVDSGQGSSVFTESRVSSQQ 673
T S T S+ P EP A + + SISV V++ G+ V
Sbjct: 3116 TPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLV---------T 3166
Query: 674 TVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPS-SSSLTGVSS 732
T+ SQ Q +ST P + A + P G S+ + S +PS S +
Sbjct: 3167 TIKMSSQAAQGNSTWPAPAEETGSSPAGTSP-GSPEMSTTLKIMSSKEPSISPEIRSTVR 3225
Query: 733 SQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQL 792
+ P + P+ ++ T P +L STS S ++P + L
Sbjct: 3226 NSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSL 3285
Query: 793 PVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYP-----VSQIPIS 847
S P P T+ S+ + S + P + + P + + S
Sbjct: 3286 SPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFS 3345
Query: 848 TPHVST-AQTGFSSLPITMAAGITQPLLTLASS---------------ATTAAIPGVSTV 891
H ST TG + + ++ ++ I + +T +S +T AIP STV
Sbjct: 3346 MWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIP--STV 3403
Query: 892 VPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLP 951
+ +++ Q ++ + + + Q+ G LG + +V ++ + L
Sbjct: 3404 LNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDV-TNTLYITSTAQTTSLV 3462
Query: 952 PQYPGDSNIAPSSNVA--SVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGG 1009
GD I +N + S+V SP + E L V+S++ G
Sbjct: 3463 SLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRAN-------VSAVKSDIAPTAGH 3515
Query: 1010 VGGQVQVSQPGG----SLAQAPTTS-SQQAVLESTQGVSQVAPAEPVAVA---QTQATQP 1061
+ Q S P + APT S T +S P V ++ T AT+
Sbjct: 3516 LS---QTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATER 3572
Query: 1062 TTLASSVDSAHSDVASG----MSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSR 1117
T ++ S S A+ ++D N+ R G + H + S + + S
Sbjct: 3573 RTTSTEHPSTWSSTAASDSWTVTDMTSNL--KVARSPGTISTMHTTSFLASSTELDSMST 3630
Query: 1118 PKLRILNVSNK----GDRVVECQLETHNRKMVTFKFDLDGDNP-EEIATIMVNNDFILAI 1172
P RI + + ET + D P + + + + I
Sbjct: 3631 PHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDI 3690
Query: 1173 ERESFVDQVREIIEKADEMLSED-VSVEPEGDQGL-----ESLQGKD------------- 1213
S+ E + M+S D S + + + L +SL D
Sbjct: 3691 LSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATAT 3750
Query: 1214 ---DYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLT--QVVHSAGRRFIVSPVPESRL 1268
G + Q+L E S +P IG TS++T + S+G F P P S+
Sbjct: 3751 TSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTF-SRPDPTSKK 3809
Query: 1269 RESKVFPSEITDTVAASTAQSPGMNLSHSASSLSL--------QQAFSELRRAQMTEGPN 1320
E + + + +T+ PG +A++L + F + +T
Sbjct: 3810 AE------QTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEAR 3863
Query: 1321 TAPPNFSH---TGPTFPVVPPFLSSIA--------------------GVPTTAAATAPVP 1357
+++ + P+ P + ++S++ + + T+
Sbjct: 3864 ATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPS 3923
Query: 1358 ATSSPPNDI--STSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSS--VV 1413
SSP I S S E P+ + T + IP S S L+S V
Sbjct: 3924 WKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVT 3983
Query: 1414 SSITIPAVVSISTTS--PSLQVPTS-----TSEIVVSSTALYPSVTVSATSASAGGSTA- 1465
+S A+VS+STT+ S + T T E+ S + S T + S+ GSTA
Sbjct: 3984 TSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAI 4043
Query: 1466 TPGPKPPAVVSQQAAGSTTVGATLTS------VSTTTSFPSTASQLSIQLSSSTSTPTLA 1519
T GP+ S++ + S + +S ++ ++FP+ + L+ TS P
Sbjct: 4044 TKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGAT 4103
Query: 1520 ETVVVSAHSLDKTSHSSTTGLAFSLS--------------APSSSSSPGAGVSSYISQPG 1565
+SA +LD ++ +S TG + + P +S P S
Sbjct: 4104 S---LSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSS 4160
Query: 1566 GLHPLVIPSVIASTPILPQAAGPTSTPLLPQV----------------------PSIPPL 1603
L P+ + ++ + Q P+STP + V S+PP
Sbjct: 4161 SLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPN 4220
Query: 1604 VQ-------------------------PVANVPAVQQTLI----HSQPQPALLPNQPHTH 1634
+ V N+ A H++P A P
Sbjct: 4221 LSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHI 4280
Query: 1635 CPEVDSDT----QPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTP 1690
++ S T + I+ + ++ + L+ E S+S Q AS + ETS VI + V+
Sbjct: 4281 MGDITSSTSVFGSSETTEIETVSSVNQGLQ----ERSTS--QVASSATETSTVI-THVSS 4333
Query: 1691 GIPTTAVAPSKLLTSTTSTCLPP------TNLPLGTVALPVTPVVTPGQVSTPVSTTTSG 1744
G TT V ++ S+ ++ P TN P T ++ S+ V+ TT
Sbjct: 4334 GDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIM--TESSGVTITTQT 4391
Query: 1745 VKPGTAPSKPPLTKAPVLPVGTELPAGTLP----SEQLPPF-PGPSLTQSQQPLEDLDAQ 1799
G A P L +P TE P P SE+ GP P +
Sbjct: 4392 GPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWTSPPSVAETS 4451
Query: 1800 LRRTLSPEMIT----VTSAVGPVSMAAPTAITEAGTQP-QKGVSQVKEGPVLATSSGAGV 1854
+L+P ++T TS + ++P + T T K + T+S +
Sbjct: 4452 YPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEPVTNSPQNL 4511
Query: 1855 FKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGIT- 1913
++ A E + S + K+V + S + VL S+ P V EP+ T
Sbjct: 4512 NNPSNEILATLAATTDIETIHPSIN-KAVTNMGTASSAHVLHSTLP----VSSEPSTATS 4566
Query: 1914 --IPGISSDVPESAHKTTASEAKSDTGQPT 1941
+P S ++ SE G+PT
Sbjct: 4567 PMVPASSMGDALASISIPGSETTDIEGEPT 4596
Score = 57.4 bits (137), Expect = 2e-07
Identities = 237/1103 (21%), Positives = 388/1103 (35%), Gaps = 166/1103 (15%)
Query: 1289 SPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPT 1348
+P + SASS++ E RA ++ + P H T SS A V
Sbjct: 3476 NPSGGKTSSASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQT--------SSPAEVSI 3527
Query: 1349 TAAATAPVPATSSP-----PNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPV 1403
TAP P S+ N IST+ EV + T + T TS P
Sbjct: 3528 LDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATERRT---TSTEHPSTWS 3584
Query: 1404 SESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGS 1463
S + S V+ +T V+ SP T+ + SST L T G S
Sbjct: 3585 STAASDSWTVTDMTSNLKVA---RSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTS 3641
Query: 1464 TATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQL-----SSSTSTPTL 1518
TP AV ++ + T+ + T+ ST S S ++SI + +S T + T
Sbjct: 3642 LVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTE 3701
Query: 1519 AETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSS----PGAGVSSYISQPGGLHPLVIPS 1574
AE V VS S D S + S S S+ G +SS + P
Sbjct: 3702 AEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQ 3761
Query: 1575 VIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQP-ALLPNQPHT 1633
+ L P ++ L + I V P A A + S+P P + Q T
Sbjct: 3762 ELT----LETMISPATSQLPFSIGHITSAVTPAA--MARSSGVTFSRPDPTSKKAEQTST 3815
Query: 1634 HCPEVDSDTQPKAP-----GIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTV 1688
P S + P +D I + + F + + + S +
Sbjct: 3816 QLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKEKS 3875
Query: 1689 TPGIP-----TTAVAPSKLLTSTTSTCLPPT------NLPLGTVALPVTPVVTPGQVSTP 1737
TP P +V+ + T+S+ + T NL GT + +P S+P
Sbjct: 3876 TPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTS-------SPSWKSSP 3928
Query: 1738 VSTTTSGVKPGTAPSKPPLTKAPVLP-VGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDL 1796
APS+ K + P T G + S + + S P
Sbjct: 3929 YER--------IAPSESTTDKEAIHPSTNTVETTGWVTSSE-------HASHSTIPAHSA 3973
Query: 1797 DAQLRRTLSPEMITVTSAVGPVSMAAPT--AITEAGTQPQKGVS-QVKE-GPVLATSSGA 1852
++L SP + T T VSM+ T T A T+P ++ ++++ P + TSS
Sbjct: 3974 SSKL---TSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTT 4030
Query: 1853 GVFKMGRFQVS-VAADGAQKEGKN-KSEDAKSVHFESSTSESSVLSSSSPESTLVK---- 1906
Q S +++ G+ K ++E S SS S+ SS SP + +
Sbjct: 4031 --------QTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNF 4082
Query: 1907 ---PEPNGITI------PGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGR 1957
E G+ + PG +S SA S S TG P + TT R
Sbjct: 4083 PAMTESGGMILAMQTSPPGATS---LSAPTLDTSATASWTGTP-------LATTQ----R 4128
Query: 1958 FSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSE---PSHLNGPSSDP 2014
F+ S+ + ++ SPP ++ E + +++P S S + PSS P
Sbjct: 4129 FTYSEKTTLFSKGPEDTSQPSPPSVE-ETSSSSSLVPIHATTSPSNILLTSQGHSPSSTP 4187
Query: 2015 --EAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDL 2072
+ FLS G + S L + NLS + + ++ S D ++ D
Sbjct: 4188 PVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADT 4247
Query: 2073 KLELRRLRDKHLKEIQD-----------LQSRQKHEIESLYTKLGKVPPAVIIPPAAPLS 2121
+ I + S +I S + G I ++
Sbjct: 4248 AVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQ 4307
Query: 2122 GRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQL 2181
G + R T S ++ +S++ ++ SG + V Q T +I S +Q
Sbjct: 4308 GLQERSTSQVASSATETSTV------ITHVSSGDATTHVTKTQATFSSGTSI--SSPHQF 4359
Query: 2182 LQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTSS 2241
+ +S N ++ +++ + S+ + G + T G T AA P + +S
Sbjct: 4360 I-------TSTNTFTDVSTNPSTSL--IMTESSGVTITTQTGPT---GAATQGPYLLDTS 4407
Query: 2242 RKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKFSAPGQLCISM------ 2295
T+ + ++ + +G K +++ P + S P L +
Sbjct: 4408 TMPYLTETPLAVTPDFMQSEKTTLISKGPK-DVSWTSPPSVAETSYPSSLTPFLVTTIPP 4466
Query: 2296 -TSNLGG---SAPISAASATSLG 2314
TS L G S+P+SA S + G
Sbjct: 4467 ATSTLQGQHTSSPVSATSVLTSG 4489
Score = 54.3 bits (129), Expect = 1e-06
Identities = 81/342 (23%), Positives = 132/342 (38%), Gaps = 43/342 (12%)
Query: 1276 SEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEG--PNTAPPNFSHTGPTF 1333
S+IT + AA++ P L+HS S R + ++ +T P S T +
Sbjct: 11745 SQITSSGAATSTTVP--TLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASL 11802
Query: 1334 PVVPPFLSSIAGVPT-----------TAAATAPVPATSSPPNDISTSVIQSEVTVPTEEG 1382
+ P +S A +PT T + + T+SP T+ + + T
Sbjct: 11803 TIRPGAETSTA-LPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTM 11861
Query: 1383 IAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVV 1442
I S G++ + GL + S + +S ++ PAV +S+ S + P + +
Sbjct: 11862 IPTSTLSLGLLETTGL-LATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNT 11920
Query: 1443 SSTALYPSVTVSATSASAGGSTAT----PGPKPPAVVSQQAAGSTTV------------- 1485
++ SV S + G+T T P PP + TT+
Sbjct: 11921 ETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLAT 11980
Query: 1486 -GATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTG----- 1539
G++ T TTT+F + A L L ++ TLA V S S + S STT
Sbjct: 11981 TGSSPTVAKTTTTFNTLAGSLFTPL-TTPGMSTLASESVTSRTSYNHRSWISTTSSYNRR 12039
Query: 1540 -LAFSLSAP-SSSSSPGAGVSSYISQPGGLHPLVIPSVIAST 1579
+ S P +S+ SPG SS S P ++P + T
Sbjct: 12040 YWTPATSTPVTSTFSPGISTSSIPSSTAATVPFMVPFTLNFT 12081
Score = 52.4 bits (124), Expect = 5e-06
Identities = 185/892 (20%), Positives = 309/892 (34%), Gaps = 112/892 (12%)
Query: 1220 SQKLEGEFKQPIPASSMPQQIGIP----TSSLTQVVHSAGRRFIVSPVPESRLRESKVFP 1275
S ++ G + PA+SM + P +S+ A + + E P
Sbjct: 106 SPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVP 165
Query: 1276 SEITDTVAASTAQSPG------MNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFS-- 1327
+E T T + ++P + ++ + + A E MT T + +
Sbjct: 166 TE-TSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPG 224
Query: 1328 HTGPTFPVV-PPFLS-SIAGVPTTAA--------ATAPVPATSSPPNDISTSVIQSEVTV 1377
T P+F + FL S G P + +T P +S P S I + +
Sbjct: 225 RTNPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPL 284
Query: 1378 PTEEGIAGVATSTGVVTSGGLPIPPVSES--PVLSSVVSSITIPAVVSISTTSPSLQVPT 1435
+ + S + SG P+S +S + + IP +++S S +
Sbjct: 285 SSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVR 344
Query: 1436 ST-SEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGST-TVGATLTSVS 1493
ST S + S + + T + + P ++ + GS T+G T TS
Sbjct: 345 STISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSAL 404
Query: 1494 TTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSP 1553
TTTS +T STS T+ S L+ ++ + + +L ++
Sbjct: 405 TTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTL 464
Query: 1554 GAGVSSYISQPGGLHPLVIPSVIASTP--ILPQAAGPTSTPLLPQVPSIPPLVQPVANVP 1611
+ + S SQ HP ST A S+ +L S +
Sbjct: 465 DSKIRS-PSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSES 523
Query: 1612 AVQQTLIHSQPQ-PALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSG 1670
QQ S+PQ + P + T AP + ++ +L S+ G
Sbjct: 524 TAQQ---FSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTL-KTSSTKG 579
Query: 1671 AQHASVSLETSLVIESTVTP---------GIPTTAVAPSK-------LLTSTTSTCLPPT 1714
S +T L+ EST P GI T + ++ LLT T++
Sbjct: 580 IWLEETSADT-LIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSA 638
Query: 1715 NLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKP--GTAPSKPPLTKAPVLPVGTELPA-- 1770
+L L T +PV+ VS VS T +G P GT PS ++ V+P + L +
Sbjct: 639 DLTLATNGVPVS-------VSPAVSKTAAGSSPPGGTKPSYTMVSS--VIPETSSLQSSA 689
Query: 1771 -------GTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLS--PEMITVTS------AV 1815
G P PF P + L + S + ++ TS A
Sbjct: 690 FREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKAT 749
Query: 1816 GPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKN 1875
++ P T+ T+P V ATS +V A +
Sbjct: 750 SSITTGTPEISTK--TKPSSAVLSSMTLSNAATSPE---------RVRNATSPLTHPSPS 798
Query: 1876 KSEDAKSVHFESSTSESSVLSSSSPESTLV---KPEPNGITIPGIS------SDVPESAH 1926
E A SV S+++E++ + P TL P+ +++P +S S S H
Sbjct: 799 GEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTH 858
Query: 1927 KTTASEAKSDTGQP------TKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPP 1980
T+ E +T P T V R + T + V V T D T + +S
Sbjct: 859 LFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPT-PVFPTMD--TWPTRSAQFSSSH 915
Query: 1981 FMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHS 2032
+ +A + L + SHL G ++ + +RD + S +P S
Sbjct: 916 LVSELRATSSTSVTNSTGSALPKISHLTGTATMSQT---NRDTFNDSAAPQS 964
Score = 52.4 bits (124), Expect = 5e-06
Identities = 131/578 (22%), Positives = 211/578 (36%), Gaps = 105/578 (18%)
Query: 1233 ASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPS-EITDTVAASTAQSP- 1290
A++ P+++ TS LT S G S + S E+ P+ T T+ + +++SP
Sbjct: 778 AATSPERVRNATSPLTHPSPS-GEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPS 836
Query: 1291 --------GMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFS-----HTGPTFPVVP 1337
G+ + S+S+ S F+ + T P+ + P S T + V
Sbjct: 837 TLSLPSVSGVKTTFSSSTPSTH-LFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPT 895
Query: 1338 PFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGG 1397
P ++ PT +A + S STSV S T + ++ TG T
Sbjct: 896 PVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNS-----TGSALPKISHLTGTATMSQ 950
Query: 1398 LPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATS 1457
++S S T P T PS STS +S+T + T ATS
Sbjct: 951 TNRDTFNDSAAPQSTTWPETSPR---FKTGLPSATTTVSTSATSLSATVMVSKFTSPATS 1007
Query: 1458 ASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPT 1517
+ S P STT+ LT+ +T + +I + T
Sbjct: 1008 SMEATSIREP--------------STTI---LTTETTNGPGSMAVASTNIPIGKGYITEG 1050
Query: 1518 LAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIA 1577
+T +H T+ SS T + F+++ S S S S + + +
Sbjct: 1051 RLDT----SHLPIGTTASSETSMDFTMAKESVSMSVSPSQS-------------MDAAGS 1093
Query: 1578 STPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPE 1637
STP G TS + V ++ + + T+ AL P TH P
Sbjct: 1094 STP------GRTS-------QFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPS 1140
Query: 1638 VDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVS-------LETSLVIESTVT- 1689
D PG + + S SS ++S + TS+++++ T
Sbjct: 1141 PD-------PG-----SARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETS 1188
Query: 1690 ----PGIP-TTAVAPSKLLTSTT--STCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTT 1742
P +P TT++ PS + TS + L P + P +L + P + P ST T
Sbjct: 1189 RWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNT 1248
Query: 1743 SGVKPGT-----APSKPPLTKAPVLPVGTELPAGTLPS 1775
+ G +PS LT A V+ G+ P T PS
Sbjct: 1249 PSIHLGAHASSESPSTIKLTMASVVKPGSYTPL-TFPS 1285
Score = 41.2 bits (95), Expect = 0.012
Identities = 102/520 (19%), Positives = 190/520 (36%), Gaps = 62/520 (11%)
Query: 604 KQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSV 663
K L S ++ + +T S V + PE Q PS+S +GT ++
Sbjct: 62 KTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATS 121
Query: 664 FTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPS 723
S +SS +T + ++ T + +T ++ + V +S +G S P
Sbjct: 122 MV-SGLSSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPW 180
Query: 724 SSSLTGVSSSQPIQHPQQQQGIQQTA-----PPQQTVQYSLSQTSTSSEATTAQPVSQPQ 778
+ V + P++ ++ A P + TV S + T+ T
Sbjct: 181 DTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDL 240
Query: 779 APQVLPQVSAGKQL---------PVSQPVPTIQGEPQI----PVATQPSVVPVHSGAHFL 825
+P+ P L P S P P G +I P+++ SV+ +
Sbjct: 241 SPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSI 300
Query: 826 PVGQPLPTPLLP--------QYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLA 877
GQ L +PL P P S IP S +S A+T + T+++ T + T
Sbjct: 301 FSGQSLTSPLSPGVPEARASTMPNSAIPFSMT-LSNAETSAERVRSTISSLGTPSISTKQ 359
Query: 878 SSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLS 937
++ T + T+ P T + + A + +G P LG + L+
Sbjct: 360 TAETILTFHAFA-------ETMDIPSTHIAKTL-------ASEWLGSPGTLGGTSTSALT 405
Query: 938 SGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVL-----SPPMPTEVLATPGYFP 992
+ P +++ + S +++++ +P +E+ AT P
Sbjct: 406 TTS------PSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTAT--LVP 457
Query: 993 TVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVA 1052
T+ ++S + P QV S P L +TS +Q+ + G S + A +
Sbjct: 458 TLGFTTLDSKIRSP-----SQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSS 512
Query: 1053 VAQTQA-TQPTTLASSVDSAHSD-VASGMSDGNENVPSSS 1090
++ + T +T + H+ V + S E P+S+
Sbjct: 513 TSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPAST 552
Score = 33.5 bits (75), Expect = 2.6
Identities = 67/291 (23%), Positives = 115/291 (39%), Gaps = 40/291 (13%)
Query: 645 PSISVLSDGTVDSGQGSSVFTESRVSSQQT-VSYGSQHEQAHSTGT-VPG----HIPSTV 698
PS +++S+ T S TE +++ T + + E++ T T VP + S +
Sbjct: 409 PSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKI 468
Query: 699 QAQSQPHGVYPPSSV-AQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQY 757
++ SQ +P + G + G+ SSS+ SS +
Sbjct: 469 RSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDI-----------------LRATTS 511
Query: 758 SLSQTSTSSEATTAQPVSQPQAPQVL----------PQVSAGKQLPVSQPVPT-IQGEPQ 806
S S+ S+ + +TAQ S+PQ Q + P S P++ VP+ + G
Sbjct: 512 STSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTT 571
Query: 807 IPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVST--AQTGFSSLPIT 864
+ ++ + + A L +G+ P Q+ V T ST +Q L
Sbjct: 572 LKTSSTKGIWLEETSADTL-IGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRA 630
Query: 865 MAAGITQPLLTLASSATTAAI-PGVS-TVVPSQLPTLLQPVTQLPSQVHPQ 913
A+ T LTLA++ ++ P VS T S P +P + S V P+
Sbjct: 631 TASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPE 681
>gi|32483399 p21-activated kinase 2 [Homo sapiens]
Length = 524
Score = 120 bits (300), Expect = 2e-26
Identities = 97/361 (26%), Positives = 167/361 (46%), Gaps = 31/361 (8%)
Query: 140 AAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKE-----------EPPPARSGS--- 185
+ P A AP+ V D + P + + +P PA G
Sbjct: 152 SGTPALNAKGTEAPAVVTEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHV 211
Query: 186 -GGGSAKEPQEERSQQQDD--IEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTE 242
G + + Q+++++ D+ +E+L T ++ +++ +IG+G+ TV+ D
Sbjct: 212 DGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYE-KIGQGASGTVFTATDVA 270
Query: 243 TTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTE 302
EVA ++ +K K E E ++K L++PNIV F DS+ + G + V V E
Sbjct: 271 LGQEVAIKQINLQKQPKKEL--IINEILVMKELKNPNIVNFLDSY---LVGDELFV-VME 324
Query: 303 LMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTG 362
+ G+L + M + + CR+ L+ L+FLH +IHRD+K DN+ + G G
Sbjct: 325 YLAGGSLTDVVTE-TCMDEAQIAAVCRECLQALEFLHANQ--VIHRDIKSDNVLL-GMEG 380
Query: 363 SVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYEEK-YDESVDVYAFGMCMLEMATSE 419
SVK+ D G S +++GTP +MAPE+ K Y VD+++ G+ +EM E
Sbjct: 381 SVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGE 440
Query: 420 YPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFF 479
PY +Y T+G + P ++ + C+ + ++R S K+LL H F
Sbjct: 441 PPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL 500
Query: 480 Q 480
+
Sbjct: 501 K 501
>gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens]
Length = 545
Score = 118 bits (295), Expect = 8e-26
Identities = 101/376 (26%), Positives = 179/376 (47%), Gaps = 24/376 (6%)
Query: 108 PAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVS 167
PA P S E ++ AT +A +P + ++V P P T ++D S
Sbjct: 168 PAVPPVS---EDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVT----PTRDVATS 220
Query: 168 QPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEI 227
S + PP A + + + K+ ++ + ++ +E+L + ++ +F+ +I
Sbjct: 221 PISPTENNTTPPDALTRN---TEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFE-KI 276
Query: 228 GRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSW 287
G+G+ TVY +D T EVA ++ ++ K E E +++ ++PNIV + DS+
Sbjct: 277 GQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNPNIVNYLDSY 334
Query: 288 ESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIH 347
+ G + V V E + G+L + M + + CR+ L+ L+FLH+ +IH
Sbjct: 335 ---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALEFLHSNQ--VIH 387
Query: 348 RDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYEEK-YDESVD 404
RD+K DNI + G GSVK+ D G S +++GTP +MAPE+ K Y VD
Sbjct: 388 RDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVD 446
Query: 405 VYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNK 464
+++ G+ +EM E PY +Y T+G + ++ + C+ +
Sbjct: 447 IWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDV 506
Query: 465 DERYSIKDLLNHAFFQ 480
++R S K+LL H F +
Sbjct: 507 EKRGSAKELLQHQFLK 522
>gi|42794767 mitogen-activated protein kinase kinase kinase 3
isoform 1 [Homo sapiens]
Length = 657
Score = 115 bits (287), Expect = 7e-25
Identities = 82/263 (31%), Positives = 138/263 (52%), Gaps = 16/263 (6%)
Query: 227 IGRGSFKTVYKGLDTETTVEVAWCELQ---DRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
+G+G+F VY D +T E+A ++Q D T E + E ++LK LQH IV++
Sbjct: 399 LGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQY 458
Query: 284 YDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTP 343
Y + +K + + E M G++K LK + + V R + RQIL+G+ +LH+
Sbjct: 459 YGCLRD--RAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNM- 515
Query: 344 PIIHRDLKCDNIFITGPTGSVKIGDLG----LATL-KRASFAKSVIGTPEFMAPEMYE-E 397
I+HRD+K NI + G+VK+GD G L T+ + +SV GTP +M+PE+ E
Sbjct: 516 -IVHRDIKGANI-LRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGE 573
Query: 398 KYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIE 457
Y DV++ G ++EM T + P++E + A I++ T P ++ ++ +
Sbjct: 574 GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHIS-EHGRDFLR 632
Query: 458 GCIRQNKDERYSIKDLLNHAFFQ 480
+ + +R S ++LL H F Q
Sbjct: 633 RIFVEAR-QRPSAEELLTHHFAQ 654
>gi|42794765 mitogen-activated protein kinase kinase kinase 3
isoform 2 [Homo sapiens]
Length = 626
Score = 115 bits (287), Expect = 7e-25
Identities = 82/263 (31%), Positives = 138/263 (52%), Gaps = 16/263 (6%)
Query: 227 IGRGSFKTVYKGLDTETTVEVAWCELQ---DRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
+G+G+F VY D +T E+A ++Q D T E + E ++LK LQH IV++
Sbjct: 368 LGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQY 427
Query: 284 YDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTP 343
Y + +K + + E M G++K LK + + V R + RQIL+G+ +LH+
Sbjct: 428 YGCLRD--RAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNM- 484
Query: 344 PIIHRDLKCDNIFITGPTGSVKIGDLG----LATL-KRASFAKSVIGTPEFMAPEMYE-E 397
I+HRD+K NI + G+VK+GD G L T+ + +SV GTP +M+PE+ E
Sbjct: 485 -IVHRDIKGANI-LRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGE 542
Query: 398 KYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIE 457
Y DV++ G ++EM T + P++E + A I++ T P ++ ++ +
Sbjct: 543 GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHIS-EHGRDFLR 601
Query: 458 GCIRQNKDERYSIKDLLNHAFFQ 480
+ + +R S ++LL H F Q
Sbjct: 602 RIFVEAR-QRPSAEELLTHHFAQ 623
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 113 bits (283), Expect = 2e-24
Identities = 371/1746 (21%), Positives = 568/1746 (32%), Gaps = 233/1746 (13%)
Query: 597 SASQTGIKQLPS---ASTGIP-TASTTSASVSTQVEPEEPEADQHQQLQYQQPS------ 646
S + +GI + + +STG P T + ++S S ++ E H + PS
Sbjct: 1096 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 1155
Query: 647 ISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHG 706
V T GS+ T SS T + + HS+ G PS+ + + G
Sbjct: 1156 APVEESTTYHRSPGSTPTTHFPASST-TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 1214
Query: 707 VYPPSSVAQGQSQ--GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTST 764
S ++ G ++ P S++ G+S + + + +P T + + ST
Sbjct: 1215 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT-SLGVGEEST 1273
Query: 765 SSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGA-- 822
+S + QP S + G + + +G + V + VH
Sbjct: 1274 TSRS---QPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPT 1330
Query: 823 --HFLPV--------------GQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMA 866
H P G + P P S ++TA G S +
Sbjct: 1331 TFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS 1390
Query: 867 AGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLP-SQVHPQLLQP-------- 917
+G T L+ A S TT+ + G ST PS+L T LP S P L +
Sbjct: 1391 SGSTGTKLSPARS-TTSGLVGEST--PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 1447
Query: 918 ----AVQSMGIPANLGQAAEVPLSS---GDVLYQGFPPRLPP----QYPGDSNIAPSSNV 966
A S + G + E S G FP Q P S+ + S
Sbjct: 1448 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE 1507
Query: 967 ASVCIHSTVLSP--PMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLA 1024
A++ ST S T ++PG T + P + + G V GSL
Sbjct: 1508 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP----DDTITSGLVEASTPTHSSTGSLH 1563
Query: 1025 QAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGN 1083
T SS A L+ Q P+ + T + P T A+ V+ +S
Sbjct: 1564 TTLTPASSTSAGLQEESTTFQSWPSS----SDTTPSPPGTTAAPVE---------VSTTY 1610
Query: 1084 ENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRK 1143
+ PSS T H+ S + R E+++ + G + + T
Sbjct: 1611 HSRPSS-------TPTTHFSASSTTLGRSEESTTVHS---SPGATGTALFPTRSATSVLV 1660
Query: 1144 MVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGD 1203
+ + E A L+ + +F R + V E
Sbjct: 1661 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 1720
Query: 1204 QGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPV 1263
F GS + G ++ + S P S + S G
Sbjct: 1721 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG-------- 1772
Query: 1264 PESRLRESKVFPSEIT-----DTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEG 1318
PES S +E T T + S ++ S + +L A S R +G
Sbjct: 1773 PESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR-----QG 1827
Query: 1319 PNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAP--------VPATSSPPNDISTSV 1370
+T ++ + T P P S+ + TT+ + +T+ ++ ST+V
Sbjct: 1828 ESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 1887
Query: 1371 IQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVL---SSVVSSITIPAVVSISTT 1427
S V T A TS V S P S + SS S + + S S+T
Sbjct: 1888 HSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST 1947
Query: 1428 SPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVS---QQAAGSTT 1484
+ ++ P ST+ +V Y S S + S+ T G + S Q A G+
Sbjct: 1948 THTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 2007
Query: 1485 VGA-TLTSV---STTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGL 1540
+ A + TSV +TTS S+ S + L ST+TP L+E T HSS
Sbjct: 2008 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK--------STTFHSSPRSP 2059
Query: 1541 AFSLSAPSSSSSPGAGVSSYIS--QPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVP 1598
A +LS P+S++S G S S +PG H P T+TP L +
Sbjct: 2060 ATTLS-PASTTSSGVSEESTTSHSRPGSTHTTAFPD-------------STTTPGLSR-- 2103
Query: 1599 SIPPLVQPVANVPAVQQTLIHSQP---QPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTL 1655
T HS P LLP T P +S T +PG D
Sbjct: 2104 ---------------HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALS 2148
Query: 1656 EEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTN 1715
+L S+ + S T+L +ST + GI + S +T P ++
Sbjct: 2149 PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS 2208
Query: 1716 LPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGT-ELPAGTLP 1774
+PG + T T PS P APV T G+ P
Sbjct: 2209 -------------TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 2255
Query: 1775 SEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPT-AITEAGTQP 1833
+ FP S T E T+ + S P+ A + +
Sbjct: 2256 TTH---FPASSTTSGHS---------------EKSTIFHSSPDASGTTPSSAHSTTSGRG 2297
Query: 1834 QKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESS 1893
+ S++ G T+ G + S + + A E S
Sbjct: 2298 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL--GVGEES 2355
Query: 1894 VLSSSSPESTLVKPEPNGITIPGISSD---VPESAHKTTASEAKSDTGQPTKVGRFQVTT 1950
S S P ST P T PG+S + V S+ +T + T + G T
Sbjct: 2356 TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTF 2415
Query: 1951 TANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELS----EPSH 2006
+ + TED T E A P Q LPA + + E S S
Sbjct: 2416 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 2475
Query: 2007 LNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESD 2066
G + P + S V + + S SP + +LP + SLS + Y S
Sbjct: 2476 STGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP----- 2530
Query: 2067 IEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRR 2126
R D L S E + +++ G P + G R
Sbjct: 2531 -----------RSPDATLSPATTTSSGVSEESSTSHSQPGST-HTTAFPDSTTTPGLSRH 2578
Query: 2127 PTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHP--QQTLHPPGNIPESGQNQLLQP 2184
T S S S ++L S SG S +S S P T PG+ Q
Sbjct: 2579 STTSHSSPGSTDTTLLPASTTTSGP-SQESTTSHSSPGSTDTALSPGSTTALSFGQESTT 2637
Query: 2185 LKPSPSSDN---LYSAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTSS 2241
SP S + + TS G + + G+ T A+ S Q + +
Sbjct: 2638 FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTH 2697
Query: 2242 RKGTFT 2247
T T
Sbjct: 2698 PASTHT 2703
Score = 112 bits (280), Expect = 4e-24
Identities = 378/1830 (20%), Positives = 599/1830 (32%), Gaps = 287/1830 (15%)
Query: 601 TGIKQLPSASTGIPTASTTS----ASVSTQVEPEE---PEADQHQQLQYQQPS---ISVL 650
T + + S+G+ STTS S T P+ P +H + P ++L
Sbjct: 2061 TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 2120
Query: 651 SDGTVDSGQGS----------SVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQA 700
T SG S T S +S+G + HS+ PG +T+
Sbjct: 2121 PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS---PGSTHTTLFP 2177
Query: 701 QSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQ-------------HPQQQQGIQQ 747
S +S S G P ++ S+S +Q H
Sbjct: 2178 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 2237
Query: 748 TAPPQQTVQY-------------SLSQTSTSSEATT---AQPVSQPQAPQVLPQVSAGKQ 791
TAP +++ Y + S TS SE +T + P + P ++G+
Sbjct: 2238 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 2297
Query: 792 -------LPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQI 844
P S + T+ G P ++ S S PT L ++ +
Sbjct: 2298 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS--------PTTTLSPASMTSL 2349
Query: 845 PISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPG-VSTVVPSQLPTLL--- 900
+ ++ S+ A T P L+ S+ ++ PG T V + PT
Sbjct: 2350 GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRG 2409
Query: 901 -QPVT--QLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGD 957
+P T P+ H L + G+ P S+ G P L G+
Sbjct: 2410 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST----QTGLPATLTTADLGE 2465
Query: 958 -SNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQV 1016
S PSS+ ++ T LSP T P+ + P +P +
Sbjct: 2466 ESTTFPSSSGST----GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 2521
Query: 1017 SQ---------PGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQAT-----QPT 1062
P +L+ A TTSS + ES+ SQ A + T T
Sbjct: 2522 KSTTFYTSPRSPDATLSPATTTSSGVSE-ESSTSHSQPGSTHTTAFPDSTTTPGLSRHST 2580
Query: 1063 TLASSVDSAH------SDVASGMSDGNENVPSSSGRHE-----GRTTKRHYRKSVRSRSR 1111
T SS S S SG S + SS G + G TT + + S +
Sbjct: 2581 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE--STTF 2638
Query: 1112 HEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILA 1171
H + S +VE H+ +P T+ +
Sbjct: 2639 HSSPGSTHTTLFPDSTTSSGIVEASTRVHSST----------GSPR--TTLSPASSTSPG 2686
Query: 1172 IERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYG-FSGSQKLEGEFKQP 1230
++ ES Q + E G F S G ++
Sbjct: 2687 LQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 2746
Query: 1231 IPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSP 1290
S P G SS G S++ P T + +P
Sbjct: 2747 TIFHSSPDASGTTPSSAHSTTSGRGES-----------TTSRISPGSTEITTLPGSTTTP 2795
Query: 1291 GMNLSHSASSLSLQQAFSELRRAQMTE---GPNTAPPNFSHTGPTFPVVPPFLSSIAGVP 1347
G++ + + S + + L A MT G + S G T V P ++ G+
Sbjct: 2796 GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR-SQPGSTHSTVSPASTTTPGLS 2854
Query: 1348 ---TTAAATAPVPA-TSSPPNDISTSVIQSE-VTVPTEEGIAGVATSTGVVTSGGLPIP- 1401
TT +++P T+ P +TSV E T + T T+ GL
Sbjct: 2855 EESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES 2914
Query: 1402 ---PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTA--LYPSVTVSAT 1456
P S + + + +++T + STT PS T T+ ST L T S
Sbjct: 2915 TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL 2974
Query: 1457 SASAGGSTATPG-PKPPAVVSQQAAGSTTV---GATLTSVSTTTSFPSTASQLSIQLSSS 1512
S S+ +T PG P P++ + T+ ATL+ +TT+S S S S S
Sbjct: 2975 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 3034
Query: 1513 TSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSS--SSSPGAGVSSYISQPGGLHPL 1570
T T ++ S S + T+ S+ G + +P S +SS G +++ S PG
Sbjct: 3035 THTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 3094
Query: 1571 VIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPA-VQQTLIHSQPQPALLPN 1629
++P ++ ++ STP S+ + P ++ A +Q+ Q P+
Sbjct: 3095 LLPDDTITSGLV-----EASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPS---- 3145
Query: 1630 QPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVT 1689
SDT P PG E + S SS+ H S S T E + T
Sbjct: 3146 ---------SSDTTPSPPGTTAAPV--EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT 3194
Query: 1690 ----PGIPTTAVAPSKLLT---------------STTSTCLPPTNLPLGTVALPVTPVVT 1730
PG TA+ P++ T ST +T LP + G T +
Sbjct: 3195 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 3254
Query: 1731 PGQVST---PVSTTTSGV--KPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPG-- 1783
P T P STT+SGV + T+ S+P T P T +P + S PG
Sbjct: 3255 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 3314
Query: 1784 -----------PSLTQSQQPLEDLDAQLRRTLSPEMITVT---SAVGPV--SMAAP-TAI 1826
SL TL P+ T + A PV S +P T +
Sbjct: 3315 DTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL 3374
Query: 1827 TEAGTQPQKGVSQVKEG--------PVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSE 1878
+ AG+ ++G S + P T++ A V ++S + G+
Sbjct: 3375 SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV------ELSTTSHGS-------PS 3421
Query: 1879 DAKSVHFESST-----SESSVLSSSSPESTLVKPEPNGITIPGI--------SSDVPESA 1925
+ HF +S+ SE S SSP +T P P T G+ SS
Sbjct: 3422 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQT 3481
Query: 1926 HKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLE 1985
S+ S G+ + T T + + + E+ + G A+ F D
Sbjct: 3482 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 3541
Query: 1986 QAVLPAVIPKKEKPELSEPSHLNGPSSD----PEAAFLSRDVDDGSGSPHSPHQLSSKSL 2041
+ E S SH + ++ P + S + + + SP S + + +L
Sbjct: 3542 TT--------SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 3593
Query: 2042 PSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESL 2101
P + LS + + S + + L S E +
Sbjct: 3594 PGSTTTPGLSEKSTTFHSSPRSPATT----------------LSPASTTSSGVSEESTTS 3637
Query: 2102 YTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAA-SV 2160
+++ G P + G R T S S S ++L S SG+ + + S
Sbjct: 3638 HSRPGST-HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSS 3696
Query: 2161 LHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDN---LYSAFTSDGAISVPSLSAPGQGTS 2217
T PG+ Q SP S + + TS G + + G+
Sbjct: 3697 SGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 3756
Query: 2218 STNTVGATVNSQAAQAQPPAMTSSRKGTFT 2247
T A+ S Q + A + T T
Sbjct: 3757 RTTLSPASSTSPGLQGESTAFQTHPASTHT 3786
Score = 108 bits (271), Expect = 5e-23
Identities = 366/1776 (20%), Positives = 598/1776 (33%), Gaps = 259/1776 (14%)
Query: 596 SSASQTGIKQLPSASTGIPTASTTSASVSTQ--VEPEEPEADQHQQLQYQQPSISVLSDG 653
S S T S T + ASTTS+ VS + P + V +
Sbjct: 3245 SEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQES 3304
Query: 654 TVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSV 713
T S T S S G + HS PG +T+ + +S
Sbjct: 3305 TASHSSPGSTDTTLSPGSTTASSLGPESTTFHSG---PGSTETTLLPDNTTASGLLEAST 3361
Query: 714 AQGQSQGQPSSSSLTGVSSSQPIQHP--QQQQGIQQTAPPQQTVQYSLSQTSTSSEATTA 771
S G P ++ S+++ + Q + T P T + + ST+S +
Sbjct: 3362 PVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGS-- 3419
Query: 772 QPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPS--------VVPVHSGAH 823
P S P + G+ S+ T+ P + AT PS +V + H
Sbjct: 3420 -PSSTPTTHFSASSTTLGR----SEESTTVHSSP-VATATTPSPARSTTSGLVEESTTYH 3473
Query: 824 FLPVG-QPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATT 882
P Q + P +T H ST T SS P T +A + +P +S +T
Sbjct: 3474 SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT-ISSAPSTTSALVEEPTSYHSSPGST 3532
Query: 883 AAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPAN------LGQAAEVPL 936
A +T P T + S Q A ++ +PA LG++ P+
Sbjct: 3533 A-----TTHFPDSSTTSGRSEESTASHSS----QDATGTIVLPARSTTSVLLGESTTSPI 3583
Query: 937 SSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQ 996
SSG + P S P + S HS+ SP +T
Sbjct: 3584 SSGSMETTALP---------GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTS------- 3627
Query: 997 PYVESNLLVPMGGVGGQVQVS--QPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVA 1054
GV + S +PG + A S+ L S +P
Sbjct: 3628 -----------SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 3676
Query: 1055 QTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEK 1114
+T TT SS +S S +SG +D + G TT + + S + H
Sbjct: 3677 LPAST--TTSGSSQESTTSHSSSGSTD--------TALSPGSTTALSFGQE--STTFHSS 3724
Query: 1115 TSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIER 1174
+ S +VE H+ +P T+ + ++
Sbjct: 3725 PGSTHTTLFPDSTTSSGIVEASTRVHSST----------GSPR--TTLSPASSTSPGLQG 3772
Query: 1175 ESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYG-FSGSQKLEGEFKQPIPA 1233
ES Q + E G F S G ++
Sbjct: 3773 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 3832
Query: 1234 SSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMN 1293
S P G SS G S++ P T + +PG++
Sbjct: 3833 HSSPDASGTTPSSAHSTTSGRGES-----------TTSRISPGSTEITTLPGSTTTPGLS 3881
Query: 1294 LSHSASSLSLQQAFSELRRAQMTE---GPNTAPPNFSHTGPTFPVVPPFLSSIAGVP--- 1347
+ + S + + L A MT G + S G T V P ++ G+
Sbjct: 3882 EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR-SQPGSTHSTVSPASTTTPGLSEES 3940
Query: 1348 TTAAATAPVPA-TSSPPNDISTSVIQSE-VTVPTEEGIAGVATSTGVVTSGGLPIP---- 1401
TT +++P T+ P +TSV + E T + T T+ GL
Sbjct: 3941 TTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAF 4000
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTA--LYPSVTVSATSAS 1459
P S + + + +++T + STT PS T T ST L T S S S
Sbjct: 4001 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS 4060
Query: 1460 AGGSTATPG-PKPPAVVSQQAAGSTTV---GATLTSVSTTTSFPSTASQLSIQLSSSTST 1515
+ +T PG P P++ + T+ ATL+ +TT+S S S S ST T
Sbjct: 4061 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 4120
Query: 1516 PTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSS--SSSPGAGVSSYISQPGGLHPLVIP 1573
++ S S + T+ S+ G + +P S +SS G +++ S PG ++P
Sbjct: 4121 TAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 4180
Query: 1574 SVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANV-PAVQQTLIHSQPQPALLPNQPH 1632
++ ++ STP S+ + P ++ +Q+ Q P+
Sbjct: 4181 DDTITSGLV-----EASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS------- 4228
Query: 1633 THCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVT--- 1689
SDT P P + E + S SS+ H S S T E + T
Sbjct: 4229 ------SSDTTPSPPSTTAVPV--EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS 4280
Query: 1690 -PGIPTTAVAPSKLLT---------------STTSTCLPPTNLPLGTVALPVTPVVTPGQ 1733
PG TA+ P++ T ST +T LP + G T +P
Sbjct: 4281 SPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS 4340
Query: 1734 VST---PVSTTTSGV--KPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPG----- 1783
T P STT+SGV + T+ S+P P T +P + S PG
Sbjct: 4341 PDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTT 4400
Query: 1784 --------PSLTQSQQPLEDLDAQLRRTLSPEMITVT---SAVGPV--SMAAP-TAITEA 1829
SL TL P+ T + A PV S +P T ++ A
Sbjct: 4401 LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA 4460
Query: 1830 GTQPQKGVSQVKEG--------PVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAK 1881
G+ ++G S + P T++ A V ++S + G+
Sbjct: 4461 GSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV------ELSTTSHGS-------PSSTP 4507
Query: 1882 SVHFESST-----SESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSD 1936
+ HF +S+ SE S SSP +T P P T G+ + +++
Sbjct: 4508 TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHF 4567
Query: 1937 TGQPTKVGRFQVTTTANKVGRFSVSK--------TEDKITDTKKEGPVASPPFMDLEQAV 1988
T GR + +TT++ ++S E+ + G A+ F D
Sbjct: 4568 PESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT- 4626
Query: 1989 LPAVIPKKEKPELSEPSHLNGPSSD----PEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQ 2044
+ E S SH + ++ P + S + + + SP S + + +LP
Sbjct: 4627 -------SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 4679
Query: 2045 NLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDK---HLKEI---------QDLQS 2092
+ LS + + S + L R + H + + S
Sbjct: 4680 TTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 4739
Query: 2093 RQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNL 2152
E + ++ G + P ++ SGR +S+ S SS + ++ + P + L
Sbjct: 4740 GLVEESTAYHSSPGST-QTMHFPESSTASGRSE---ESRTSHSSTTHTI-SSPPSTTSAL 4794
Query: 2153 SGQSAASVLHPQQ--TLHPPGNIPESGQNQLLQPLKPSPSSDN---LYSAFTSDGAISVP 2207
+ + P T H P + SG+++ SP ++ L + FT+ G I+
Sbjct: 4795 VEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAES 4854
Query: 2208 SLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTSSRK 2243
+ G+ T T+ +T + A+ + SS +
Sbjct: 4855 TTFYISPGSMET-TLASTATTPGLSAKSTILYSSSR 4889
Score = 97.4 bits (241), Expect = 1e-19
Identities = 378/1765 (21%), Positives = 585/1765 (33%), Gaps = 260/1765 (14%)
Query: 575 VREEQEKKKQEESSLKQQVEQSSASQTGIKQ----LPSASTGIPTASTTSASVSTQVEPE 630
V EE + + S V +S + G+ + + S+S G + + +T V E
Sbjct: 2351 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGE 2410
Query: 631 EPE------ADQHQQLQYQQPSISVLSDG--------------------TVDSGQGSSVF 664
EP A H L + + S L++ T D G+ S+ F
Sbjct: 2411 EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF 2470
Query: 665 TESRVSSQQTVSYGSQHEQAHSTGTVPGHI-PSTVQAQSQPHGVYPPS----------SV 713
S S+ T+S + P + PS+ + + P PS S
Sbjct: 2471 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 2530
Query: 714 AQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQP 773
+ P++++ +GVS H Q TA P T LS+ ST+S ++
Sbjct: 2531 RSPDATLSPATTTSSGVSEESSTSH-SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 2589
Query: 774 VSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPT 833
+ +LP + S P P +T ++ P + A L GQ T
Sbjct: 2590 DTT-----LLPASTT-----TSGPSQESTTSHSSPGSTDTALSPGSTTA--LSFGQESTT 2637
Query: 834 PLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLA-SSATTAAIPGVSTVV 892
P S P ST +G + + P TL+ +S+T+ + G ST
Sbjct: 2638 --FHSSPGSTHTTLFPD-STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTF 2694
Query: 893 PSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPP 952
+ P+ H P+ + A + ++ S G FP
Sbjct: 2695 QTH-----------PASTHTTPSPPSTAT----APVEESTTYHRSPGSTPTTHFPASSTT 2739
Query: 953 Q-YPGDSNIAPSSNVAS----VCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPM 1007
+ S I SS AS HST T +PG P + P
Sbjct: 2740 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP---GSTTTP- 2795
Query: 1008 GGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASS 1067
G + S S ++PTT+ A + S GV + + T +QP + S+
Sbjct: 2796 ----GLSEASTTFYSSPRSPTTTLSPASMTSL-GVGEEST--------TSRSQPGSTHST 2842
Query: 1068 VDSAHSDVASGMSDGNENVPSSS-GRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVS 1126
V A S G+S+ + V SSS G E R SVR SRP
Sbjct: 2843 VSPA-STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRP-------- 2893
Query: 1127 NKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIE 1186
TH F D E +T + S + +
Sbjct: 2894 ----------ASTHT---TLFTEDSTTSGLTEESTAFPGSP-------ASTQTGLPATLT 2933
Query: 1187 KADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSS 1246
AD L E+ + P + SG L GE + S + +P S
Sbjct: 2934 TAD--LGEESTTFPSSSGSTGTTLSPARSTTSG---LVGESTPSRLSPSSTETTTLPGSP 2988
Query: 1247 LTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQA 1306
T + F SP R ++ + P+ T S+ S + SHS + A
Sbjct: 2989 TTPSLSEKSTTFYTSP----RSPDATLSPATTT-----SSGVSEESSTSHSQPGSTHTTA 3039
Query: 1307 FSELRRAQMTEGPNTAP-PNFSHTGPTFPVVPP--FLSSIAGVPTTAAATAP--VPATSS 1361
F + + T G + P + S G T + P +S G +T ++P T
Sbjct: 3040 FPD---STTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLL 3096
Query: 1362 PPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSI----- 1416
P + I++ ++++ + G + TS GL ES S SS
Sbjct: 3097 PDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQ----EESTTFQSWPSSSDTTPS 3152
Query: 1417 ---TIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPA 1473
T A V +STT S T T+ SST L S S T S+ G+T T A
Sbjct: 3153 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS-EESTTVHSSPGATGT------A 3205
Query: 1474 VVSQQAAGSTTVGATLTS-----VSTTTSFPSTASQLSIQLSSST--STPTLAETVVVSA 1526
+ ++A S VG TS + TT+ P + + + S+T S+P +T + A
Sbjct: 3206 LFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPA 3265
Query: 1527 H------SLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYI--SQPGGLHPLVIPSVIAS 1578
S + T+ S G + + P S++ PG S S PG + P +
Sbjct: 3266 STTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTA 3325
Query: 1579 TPILPQAA------GPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPH 1632
+ + P++ G T T LLP + L++ A+ P T P L P
Sbjct: 3326 SSLGPESTTFHSGPGSTETTLLPDNTTASGLLE--ASTPVHSST---GSPHTTLSPAGST 3380
Query: 1633 THCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIES-TVTPG 1691
T + +S T P D S F E S++ S + T S T+
Sbjct: 3381 TR--QGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 3438
Query: 1692 IPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVST---PVSTTTSGVKPG 1748
+T V S + T+TT + P + G V T +PG T P S TTSG
Sbjct: 3439 EESTTVHSSPVATATTPS--PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 3496
Query: 1749 TAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEM 1808
+ S T T L E P T + + R S
Sbjct: 3497 STTSHSSTTHTISSAPST---TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 3553
Query: 1809 ITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADG 1868
+ A G + + P T + + S + G + T+ G + S
Sbjct: 3554 HSSQDATGTIVL--PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 3611
Query: 1869 AQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKT 1928
+ + A + S SE S S S P ST P+ T PG+ S H T
Sbjct: 3612 SPRSPATTLSPASTT--SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL------SRHST 3663
Query: 1929 TASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAV 1988
T+ + T TTT+ + S + TDT + E
Sbjct: 3664 TSHSSPGSTDTTLLPAS---TTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 3720
Query: 1989 LPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQ 2048
P + + ++ S V +GSP + +S + P Q
Sbjct: 3721 F------HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG---LQ 3771
Query: 2049 SLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKV 2108
S +F + S+ H + E + Y +
Sbjct: 3772 GESTAFQTHPAST---------------------HTTPSPPSTATAPVEESTTYHRSPGS 3810
Query: 2109 PPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQT-- 2166
P P ++ SG + T S + ++ + SG G+S S + P T
Sbjct: 3811 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR--GESTTSRISPGSTEI 3868
Query: 2167 LHPPGNIPESGQNQLLQPLKPSPSSDNLY---SAFTS--DGAISVPSLSAPGQ-----GT 2216
PG+ G ++ SP S ++ TS G S S S PG
Sbjct: 3869 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP 3928
Query: 2217 SSTNTVGATVNSQAAQAQPPAMTSS 2241
+ST T G + S + P T +
Sbjct: 3929 ASTTTPGLSEESTTVYSSSPGSTET 3953
Score = 95.5 bits (236), Expect = 5e-19
Identities = 326/1481 (22%), Positives = 511/1481 (34%), Gaps = 197/1481 (13%)
Query: 578 EQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTA-STTSASVSTQVEPEEPEADQ 636
EQ + +Q+ + ++ +G Q+ ++ +TTSAS + +P +D
Sbjct: 136 EQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDY 195
Query: 637 HQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPS 696
+ + S + + +DS S ES VS + G+ +HS +V P
Sbjct: 196 GVSVTFITGSTA--TKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPK 253
Query: 697 TVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQ 756
T P + A ++ P S++ G+S + + +T P +T
Sbjct: 254 T-----------SPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSP-DRTLSPARTTS 301
Query: 757 YSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVV 816
+S+ ST+S + P P ++ S +P P T PS +
Sbjct: 302 SGVSEKSTTSHSRPG-PTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL 360
Query: 817 PVHSGAHFLPVGQPLPTPLLPQYPVSQI-PISTP-HVSTAQ--TGFSSLPITMAAGITQP 872
S G T L S + STP H ST T S T G
Sbjct: 361 GPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTT 420
Query: 873 LLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAA 932
+ SS T+ P +T +L T PS P LG +
Sbjct: 421 FQSWPSSKDTSPAPSGTTSAFVKLSTTYH---SSPSST------PTTHFSASSTTLGHSE 471
Query: 933 E-VPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVA-SVCIHSTVLSPPMPTEVLATPGY 990
E P+ S V PP + A S +V S H + P T+ + +
Sbjct: 472 ESTPVHSSPVATATTPP--------PARSATSGHVEESTAYHRS----PGSTQTM----H 515
Query: 991 FPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTT-SSQQAVLESTQGVSQVAPAE 1049
FP S G + S P + A A T+ S E+T +
Sbjct: 516 FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG 575
Query: 1050 PVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHE-----GRTTKRHYRK 1104
++ + P +A++V A S + + D + P SSG E G TTK
Sbjct: 576 RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPS-PISSGSMETTALPGSTTKPGL-- 632
Query: 1105 SVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIM- 1163
S +S + + P L S V E +H+R T G +T M
Sbjct: 633 SEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG------STTMP 686
Query: 1164 -VNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQK 1222
++ + + D L + + E+ D+ SG
Sbjct: 687 GLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLL- 745
Query: 1223 LEGEFKQPIPASSM-PQQIGIPTSSLTQ-----VVHSAGRRFIVSPVPESRLRE------ 1270
E P+ +S+ P P S T+ HS P P +
Sbjct: 746 ---EASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 802
Query: 1271 -SKVFPSEITDTVAASTAQSPGM----NLSHSASSLSLQQAFSELRRAQMTEGPNT-APP 1324
S PS I T ++ + + G+ HS+ + F E + T G +
Sbjct: 803 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPE---SDTTSGRGEESTT 859
Query: 1325 NFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVP-TEEGI 1383
+ S T T P S++ PT+ ++ AT+ P+ +TS E T + +
Sbjct: 860 SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 919
Query: 1384 AGV----ATSTGVVTSGGLPIPPVSESPVLSSVV-SSITIPAVVSISTT------SPSLQ 1432
G A ST V G P+S + ++ + S T P + STT SP+
Sbjct: 920 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT 979
Query: 1433 V-PTSTSEIVVSSTALYPSVTVSATSASA-GGSTATPGPKPPAVVSQQAAGSTTVGATLT 1490
+ P ST+ VS + +T +A ST TPG + S + GST TL
Sbjct: 980 LSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT--TLL 1037
Query: 1491 SVSTTTSFPSTASQLSIQLSSSTSTP-TLAETVVVSAHSLDKTSHSS------------- 1536
STTTS PS S S S ST T + T +S T HS+
Sbjct: 1038 PASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDST 1097
Query: 1537 --------TTGLAFSLSAPSSSSSPGAGVS--------SYISQPGGLHPLVIPSVIASTP 1580
+T + S +P ++ SP + S ++ + P H P A+ P
Sbjct: 1098 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 1157
Query: 1581 I-----LPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPA-LLPNQPH-T 1633
+ ++ G T T P + + + T+ HS P + P+ H T
Sbjct: 1158 VEESTTYHRSPGSTPTTHFP--------ASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 1209
Query: 1634 HCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIP 1693
+S T +PG +I TL ++ G AS + +S P P
Sbjct: 1210 TSGRGESTTSRISPGSTEITTLP-------GSTTTPGLSEASTTFYSS--------PRSP 1254
Query: 1694 TTAVAPSKLLT------STTSTCLPPTNLPLGTVALPVTP--------VVTPGQVST--- 1736
TT ++P+ + + STTS P + + A TP V + + ST
Sbjct: 1255 TTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETT 1314
Query: 1737 --PVSTTTS--GVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPG-PSLTQSQQ 1791
P STTTS G +P T S+P T + TE + +E+ FPG P+ TQ+
Sbjct: 1315 VFPHSTTTSVHGEEPTTFHSRPASTHTTLF---TEDSTTSGLTEESTAFPGSPASTQTGL 1371
Query: 1792 PLEDLDAQLRRTLSPEMITVTSAVGPV-SMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
P A L E T S+ G + +P T +G + S++ T+
Sbjct: 1372 PATLTTAD----LGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTL 1427
Query: 1851 GAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPN 1910
+ S + + A + S SE S S S P ST P+
Sbjct: 1428 PGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT--SSGVSEESSTSHSQPGSTHTTAFPD 1485
Query: 1911 GITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTT 1951
T +S + S ++EA G T Q +TT
Sbjct: 1486 STTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 1526
Score = 92.4 bits (228), Expect = 5e-18
Identities = 233/1125 (20%), Positives = 365/1125 (32%), Gaps = 196/1125 (17%)
Query: 1218 SGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSP-VPESRLRESKVFPS 1276
S + L GE +S + +P S+ T + F SP P++ L + S
Sbjct: 3211 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS 3270
Query: 1277 EITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPN--TAPPNFSHTGPTFP 1334
+++ S ++ + + S ++ E + + G T P + P
Sbjct: 3271 GVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 3330
Query: 1335 VVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVT 1394
F S G +T P T+S + ST V S + T AG T G T
Sbjct: 3331 ESTTFHS---GPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST 3387
Query: 1395 S--------GGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTA 1446
+ P PP + S A V +STTS T T+ SST
Sbjct: 3388 TFQSWPNSKDTTPAPPTTTS-------------AFVELSTTSHGSPSSTPTTHFSASSTT 3434
Query: 1447 LYPSVTVSATSASAGGSTATPGPK---PPAVVSQQAAGSTTVGATLTSVSTTTSFPSTAS 1503
L S + +S + TP P +V + ++ G+T T + S
Sbjct: 3435 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRG 3494
Query: 1504 QLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQ 1563
+ S SST+ + SA + TS+ S+ G + P SS++ G S S
Sbjct: 3495 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 3554
Query: 1564 PG--GLHPLVIPSVIASTPIL------PQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQ 1615
+V+P+ ++ +L P ++G T LP + P L + +
Sbjct: 3555 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE--------KS 3606
Query: 1616 TLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHAS 1675
T HS P+ P + G+ + T + HS G+ H
Sbjct: 3607 TTFHSSPRSPATTLSP----------ASTTSSGVSEEST---------TSHSRPGSTH-- 3645
Query: 1676 VSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVS 1735
T+ +ST TPG+ + ST +T LP + G+ T + G
Sbjct: 3646 ----TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTD 3701
Query: 1736 T---PVSTT--TSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQ 1790
T P STT + G + T S P T + P T + ++
Sbjct: 3702 TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTT---------------SSGIVEAS 3746
Query: 1791 QPLEDLDAQLRRTLSPEMITVTSAVGPVS--MAAPTAITEAGTQPQKGVSQVKEGPVLAT 1848
+ R TLSP T G + P + + P + V+E
Sbjct: 3747 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 3806
Query: 1849 SSGAGVFKMGRFQVSVAADGAQKEGK--NKSEDAK-----SVHFESSTSESSVLSSSSPE 1901
S G+ F S G ++ + S DA S H +S S S SP
Sbjct: 3807 SPGST--PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 3864
Query: 1902 STLVKPEPNGITIPGISS----------------------------------DVPESAHK 1927
ST + P T PG+S P S H
Sbjct: 3865 STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 3924
Query: 1928 TTASEAKSDTG------------------------QPTKVGRFQVTTTANK-VGRFSVSK 1962
T + + + G T V R + TT ++ +
Sbjct: 3925 TVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLF 3984
Query: 1963 TEDKITDTKKEGPVASPPFMDLEQAVLPAVIPK----KEKPELSEPSHLNGPSSDPEAAF 2018
TED T E A P Q LPA + +E S G P +
Sbjct: 3985 TEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST 4044
Query: 2019 LSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRR 2078
S V + + S SP + +LP + SLS + Y S R
Sbjct: 4045 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP----------------R 4088
Query: 2079 LRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRS 2138
D L S E + +++ G P + SG + PT S S+ S
Sbjct: 4089 SPDATLSPATTTSSGVSEESSTSHSQPGST-HTTAFPDSTTTSGLSQEPTTSHSSQGSTE 4147
Query: 2139 SSL--GNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSS-DNLY 2195
++L G+ + G S +S + TL P I L++ P+ SS +L+
Sbjct: 4148 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG----LVEASTPTHSSTGSLH 4203
Query: 2196 SAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTS 2240
+ T P+ S + T + +S PP+ T+
Sbjct: 4204 TTLT-------PASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTA 4241
Score = 91.3 bits (225), Expect = 1e-17
Identities = 391/1819 (21%), Positives = 599/1819 (32%), Gaps = 314/1819 (17%)
Query: 596 SSASQTGIKQLPSAST--GIPTASTTSASVSTQVE-------PEEPEADQHQQLQYQQPS 646
SS+ TG P+ ST G+ ST S + E P P + Y P
Sbjct: 2472 SSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 2531
Query: 647 I--SVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAH-STGTVPGHIPSTVQAQSQ 703
+ LS T S S V ES S Q GS H A + T PG + + S
Sbjct: 2532 SPDATLSPATTTS---SGVSEESSTSHSQP---GSTHTTAFPDSTTTPGLSRHSTTSHSS 2585
Query: 704 PHG----VYPPSSVAQGQSQGQPSSSSLTGVS-------SSQPIQHPQQQQGIQQTAPPQ 752
P + P S+ G SQ +S S G + S+ + Q+ +
Sbjct: 2586 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGST 2645
Query: 753 QTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQI----P 808
T + S TS+ + + S +P+ P S P +QGE P
Sbjct: 2646 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS-------PASSTSPGLQGESTTFQTHP 2698
Query: 809 VATQPSVVPVHSGAHFLPVGQPLPTPLLP-QYPVSQIPIS--TPHVSTAQTGFSSLPITM 865
+T + P + PV + P P + P S T S T F S P
Sbjct: 2699 ASTHTTPSPPSTAT--APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD-- 2754
Query: 866 AAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLP-SQVHPQLLQPAVQSMGI 924
A+G T +S+ +T + G ST S++ +T LP S P L + +
Sbjct: 2755 ASGTTP-----SSAHSTTSGRGESTT--SRISPGSTEITTLPGSTTTPGLSEASTTFYSS 2807
Query: 925 PANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEV 984
P + + +S L G PG ++ S V+ + LS T
Sbjct: 2808 PRS--PTTTLSPASMTSLGVGEESTTSRSQPGSTH----STVSPASTTTPGLSEESTTVY 2861
Query: 985 LATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQ 1044
++PG T V P + + G S+P + T S +T G+++
Sbjct: 2862 SSSPGSTETTVFP---RSTTTSVRGEEPTTFHSRPASTHTTLFTEDS------TTSGLTE 2912
Query: 1045 VAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRK 1104
+ A P + A TQ P TL + + + + + PSSSG TT R
Sbjct: 2913 ESTAFPGSPASTQTGLPATLTT----------ADLGEESTTFPSSSG--STGTTLSPARS 2960
Query: 1105 SVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMV 1164
+ SR L+ S+ + T + + F +P+ AT+
Sbjct: 2961 TTSGLVGESTPSR-----LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD--ATLSP 3013
Query: 1165 NNDFILAIERESFVDQVR----EIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGS 1220
+ ES + D + +S EP S QG + S
Sbjct: 3014 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTAS---HSSQGSTEATLSPG 3070
Query: 1221 QKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITD 1280
ASS+ QQ + HS+ + +P+ + V S T
Sbjct: 3071 S---------TTASSLGQQ--------STTFHSSPGDTETTLLPDDTITSGLVEASTPTH 3113
Query: 1281 TVAAS--TAQSPGMNLSH--SASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVV 1336
+ S T +P + S S + Q S G AP S T + P
Sbjct: 3114 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 3173
Query: 1337 PPFLSSIAGVPTTAAATAPVPATSSP--------PNDISTSVIQSE-VTVPTEEGIAGVA 1387
P A T + SSP P +TSV+ E T P G
Sbjct: 3174 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETT 3233
Query: 1388 TSTGVVTSGGL-------------PIPPVSESPVLSSVVS-------------------- 1414
G T+ GL P +S + SS VS
Sbjct: 3234 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 3293
Query: 1415 SITIPAVVSISTTSPSLQVPTSTSEIVVSSTA--------------------LYPSVTVS 1454
S T+P V ST S S T T+ S+TA L P T +
Sbjct: 3294 STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTA 3353
Query: 1455 A----TSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLS 1510
+ S ST +P S G +T + + TT P T + ++LS
Sbjct: 3354 SGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELS 3413
Query: 1511 -----SSTSTPTL---AETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGV----S 1558
S +STPT A + + T HSS A + PS + S +G+ +
Sbjct: 3414 TTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA---TTPSPARSTTSGLVEEST 3470
Query: 1559 SYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLI 1618
+Y S PG + P +T + + + + + S P + P T
Sbjct: 3471 TYHSSPGSTQTMHFPE-SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP----TSY 3525
Query: 1619 HSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIK-TLEEKLRSLFSE--HSSSGAQHAS 1675
HS P + P + S+ + D T+ RS S S+ + +S
Sbjct: 3526 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 3585
Query: 1676 VSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVS 1735
S+ET+ + ST TPG+ + S +T P + G T PG
Sbjct: 3586 GSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH 3645
Query: 1736 T---PVSTTTSGVK--PGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGP------ 1784
T P STTT G+ T+ S P T +LP T + S G
Sbjct: 3646 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALS 3705
Query: 1785 -------SLTQSQQPLEDLDAQLRRTLSPEMITVTSAV-----------GPVSMAAPTAI 1826
S Q TL P+ T + V P + +P +
Sbjct: 3706 PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS 3765
Query: 1827 TEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSE-DAKSVHF 1885
T G Q + Q T S + A + ++S + HF
Sbjct: 3766 TSPGLQGESTAFQTHPASTHTTPSPPS---------TATAPVEESTTYHRSPGSTPTTHF 3816
Query: 1886 ESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGR 1945
+ SS S S +ST+ P+ S P SAH TT+ +S T + G
Sbjct: 3817 PA----SSTTSGHSEKSTIFHSSPDA------SGTTPSSAHSTTSGRGESTTSR-ISPGS 3865
Query: 1946 FQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAV-IPKKEKPELSEP 2004
++TT +S+ + + P L A + ++ + ++ S+P
Sbjct: 3866 TEITTLPGSTTTPGLSEASTTFYSSPRS------PTTTLSPASMTSLGVGEESTTSRSQP 3919
Query: 2005 SHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNE 2064
GS HS +S S + LS+ + ++SS E
Sbjct: 3920 -----------------------GSTHS--TVSPASTTTPGLSEESTTVYSSS--PGSTE 3952
Query: 2065 SDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTK---LGKVPPAVIIPPAAPLS 2121
+ + +RR +E SR +L+T+ + P +P S
Sbjct: 3953 TTVFPRSTTTSVRR------EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS 4006
Query: 2122 GRRRRP----TKSKGSKS----SRSSSLGNK-SPQLS--GNLSGQSAASVLHPQ--QTLH 2168
+ P T G +S S S S G K SP S L G+S S L P +T
Sbjct: 4007 TQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTT 4066
Query: 2169 PPGNIPESGQNQLLQPLKPSPSSDN--LYSAFTSDGAISVPSLSAPGQGTSSTNTVGATV 2226
PG+ ++ SP S + L A T+ +S S ++ Q S+ T
Sbjct: 4067 LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 4126
Query: 2227 NSQAAQAQPPAMTSSRKGT 2245
+ + +Q P + S +G+
Sbjct: 4127 TTTSGLSQEPTTSHSSQGS 4145
Score = 79.3 bits (194), Expect = 4e-14
Identities = 321/1485 (21%), Positives = 513/1485 (34%), Gaps = 242/1485 (16%)
Query: 583 KQEESSLKQQVEQSSASQTGIKQLPSASTGI------PTASTTSASVSTQVEPEE---PE 633
+ EES+ SS TG LP+ ST T+ +S S+ T P P
Sbjct: 3546 RSEEST----ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 3601
Query: 634 ADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSY---GSQHEQAH-STGT 689
+ + P S T S + T S VS + T S+ GS H A + T
Sbjct: 3602 LSEKSTTFHSSPR----SPATTLSPAST---TSSGVSEESTTSHSRPGSTHTTAFPDSTT 3654
Query: 690 VPGHIPSTVQAQSQPHG----VYPPSSVAQGQSQGQPSSSSLTGVS-------SSQPIQH 738
PG + + S P + P S+ G SQ +S S +G + S+ +
Sbjct: 3655 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSF 3714
Query: 739 PQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPV 798
Q+ + T + S TS+ + + S +P+ P S
Sbjct: 3715 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS-------PASSTS 3767
Query: 799 PTIQGEPQI----PVATQPSVVPVHSGAHFLPVGQPLPTPLLP-QYPVSQIPIS--TPHV 851
P +QGE P +T + P + PV + P P + P S T
Sbjct: 3768 PGLQGESTAFQTHPASTHTTPSPPSTAT--APVEESTTYHRSPGSTPTTHFPASSTTSGH 3825
Query: 852 STAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLP-SQV 910
S T F S P A+G T +S+ +T + G ST S++ +T LP S
Sbjct: 3826 SEKSTIFHSSPD--ASGTTP-----SSAHSTTSGRGESTT--SRISPGSTEITTLPGSTT 3876
Query: 911 HPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVC 970
P L + + P + + +S L G PG ++ S V+
Sbjct: 3877 TPGLSEASTTFYSSPRS--PTTTLSPASMTSLGVGEESTTSRSQPGSTH----STVSPAS 3930
Query: 971 IHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTS 1030
+ LS T ++PG T V P + V+ +P ++ +T
Sbjct: 3931 TTTPGLSEESTTVYSSSPGSTETTVFPRSTTT----------SVRREEPTTFHSRPASTH 3980
Query: 1031 SQQAVLEST-QGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSS 1089
+ +ST G+++ + A P + A TQ P TL + + + + + PSS
Sbjct: 3981 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT----------ADLGEESTTFPSS 4030
Query: 1090 SGRHEGRTTKRHYRKSVRSRSRHEKT-SRPKLRILNVSNKGDRVVECQLETHNRKMVTFK 1148
SG TK +S S E T SR L+ S+ + T + +
Sbjct: 4031 SG---STGTKLSPARSTTSGLVGESTPSR-----LSPSSTETTTLPGSPTTPSLSEKSTT 4082
Query: 1149 FDLDGDNPEEIATIMVNNDFILAIERESFVDQVR----EIIEKADEMLSEDVSVEPEGDQ 1204
F +P+ AT+ + ES + D + +S EP
Sbjct: 4083 FYTSPRSPD--ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTS- 4139
Query: 1205 GLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVP 1264
S QG + S ASS+ QQ + HS+ + +P
Sbjct: 4140 --HSSQGSTEATLSPGS---------TTASSLGQQ--------STTFHSSPGDTETTLLP 4180
Query: 1265 ESRLRESKVFPSEITDTVAAS--TAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTA 1322
+ + V S T + S T +P S++S LQ+ + + + +
Sbjct: 4181 DDTITSGLVEASTPTHSSTGSLHTTLTPA-----SSTSTGLQEESTTFQSWPSSSDTTPS 4235
Query: 1323 PPNFS----------HTGPTFPVVPPFLSSIAGV-----PTTAAATAPVPATSSPPNDIS 1367
PP+ + H+ P+ F +S + TT ++ T+ P +
Sbjct: 4236 PPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 4295
Query: 1368 TSVIQSE-VTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSIST 1426
TSV+ E T P G G T+ GL + SS S T + S ++
Sbjct: 4296 TSVLVGEPTTSPISSGSTETTALPGSTTTAGL---SEKSTTFYSSPRSPDTTLSPASTTS 4352
Query: 1427 TSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVG 1486
+ S + TS S T +PS ST PG + S + GST
Sbjct: 4353 SGVSEESTTSHSRPGSMHTTAFPS------------STTMPGVSQESTASHSSPGST--D 4398
Query: 1487 ATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSA 1546
TL+ STT S S ST T L + S T S+TG + +
Sbjct: 4399 TTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 4458
Query: 1547 PSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPI---LPQAAGPTSTPLLPQVPSIPPL 1603
P+ S++ +++ S P P S + P+STP S L
Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 4518
Query: 1604 VQPVANVPAVQQTLIHSQPQPALL---PNQPHTHCPEVDSDTQPKAPG------IDDIKT 1654
+ + + T +HS P P + T +S T +PG + T
Sbjct: 4519 GR------SEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNT 4572
Query: 1655 LEEKLRSLFSEHSSSGAQHASVSLETSLVIESTV----TPGIPTTAVAPSKLLT---STT 1707
+ + HSS+ +S TS ++E +PG T P T S
Sbjct: 4573 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 4632
Query: 1708 STCLPPTNLPLGTVALP------------VTPVVTPGQVST---PVSTTTSGVKP----- 1747
ST + GT+ LP T ++ G + T P STTT G+
Sbjct: 4633 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTF 4692
Query: 1748 GTAPSKPPLT--KAPVLPVGTELPAGTLPSEQL--PPFPGPSLTQSQQPLEDLDAQ---- 1799
++PS P T A +G + T+ S + P P+ + + +E+ A
Sbjct: 4693 HSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP 4752
Query: 1800 -LRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMG 1858
+T+ + S S + ++ T + P S + E P + S G
Sbjct: 4753 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPT-SYHSSPGSIATT 4811
Query: 1859 RFQVSVAADGAQKE--GKNKSEDAKSV-----HFESS----TSESSVLSSSSPESTLVKP 1907
F S G +E + S D + HF +S S + +S S E+TL
Sbjct: 4812 HFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLA-- 4869
Query: 1908 EPNGITIPGI---------SSDVPESAHKTTASEAKSDTGQPTKV 1943
+ T PG+ SS P+ + + S +G+PT +
Sbjct: 4870 --STATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSL 4912
Score = 78.6 bits (192), Expect = 7e-14
Identities = 170/754 (22%), Positives = 268/754 (35%), Gaps = 106/754 (14%)
Query: 1218 SGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSP-VPESRLRESKVFPS 1276
S + L GE +S + +P S+ T + F SP P++ L + S
Sbjct: 4294 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS 4353
Query: 1277 EITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPN--TAPPNFSHTGPTFP 1334
+++ S ++ M+ + SS ++ E + + G T P + P
Sbjct: 4354 GVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 4413
Query: 1335 VVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVT 1394
F SS TT P T+S + ST V S + T AG T G T
Sbjct: 4414 ESTTFHSSPGSTETTLL---PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST 4470
Query: 1395 S--------GGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTA 1446
+ P PP + S A V +STTS T T+ SST
Sbjct: 4471 TFQSWPNSKDTTPAPPTTTS-------------AFVELSTTSHGSPSSTPTTHFSASSTT 4517
Query: 1447 LYPSVTVSATSASAGGSTATPGPK---PPAVVSQQAAGSTTVGATLTSVSTTTSFPSTAS 1503
L S + +S + TP P +V + ++ G+T T ++ S
Sbjct: 4518 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRG 4577
Query: 1504 QLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQ 1563
+ S SST+ + SA + TS+ S+ G + P SS++ G S S
Sbjct: 4578 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 4637
Query: 1564 PG--GLHPLVIPSVIASTPIL------PQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQ 1615
+V+P+ ++ +L P ++G T LP + P L + +
Sbjct: 4638 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE--------KS 4689
Query: 1616 TLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHAS 1675
T HS P + P TH S T ++ EE S +++ +
Sbjct: 4690 TTFHSSPS-----STPTTHF-SASSTTLGRS---------EESTTVHSSPVATATTPSPA 4734
Query: 1676 VSLETSLVIESTV---TPGIPTTAVAPSKLL------------TSTTSTCLPPTNLPLGT 1720
S + LV EST +PG T P +STT T P +
Sbjct: 4735 RSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL 4794
Query: 1721 VALPVTPVVTPGQVST---PVSTTTSG-VKPGTAPSKPPLTKAPVLPVGTELPAGTLPSE 1776
V P + +PG ++T P S+TTSG + TA P T T LPA S
Sbjct: 4795 VEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGI-----TPLPAHFTTSG 4849
Query: 1777 QLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKG 1836
++ S T P ++ L T + ++ S + S +P +
Sbjct: 4850 RI----AESTTFYISP-GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSS 4904
Query: 1837 VSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLS 1896
+S G + S A F S G +E + + +K E++ S S+ +
Sbjct: 4905 IS----GEPTSLYSQAESTHTTAFPASTTTSGLSQE--STTFHSKPGSTETTLSPGSITT 4958
Query: 1897 SS----------SPESTLVKPEPNGITIPGISSD 1920
SS P S L P T+PG+S +
Sbjct: 4959 SSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992
Score = 72.8 bits (177), Expect = 4e-12
Identities = 218/985 (22%), Positives = 331/985 (33%), Gaps = 126/985 (12%)
Query: 1324 PNFSHTGPTFPVVPPFLSSI-AGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEG 1382
P S TG + P S+ G PTT + TS P+ +++ ++ T +
Sbjct: 394 PVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPS 453
Query: 1383 IAGVATSTGVVTSGGLPIPPVSES-PVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIV 1441
+T T ++ + ES PV SS V++ T P S TS ++ T+
Sbjct: 454 ----STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR-SATSGHVEESTAYHRSP 508
Query: 1442 VSSTALY--PSVTVSA---TSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTT 1496
S+ ++ S T S SA+ GST P+ + A T+ ++L S TT
Sbjct: 509 GSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTA--ALAHTSYHSSLGSTETTH 566
Query: 1497 -SFPSTASQLSIQLSSSTSTPTLAETVVVSAHSL------DKTSHSSTTGLAFSLSAPSS 1549
ST S S + +S S+P T V+ A S D T ++G + + P S
Sbjct: 567 FRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS 626
Query: 1550 SSSPGAGVSS--YISQPGGLHPLVIPSVIASTPILPQAA------GPTSTPLLPQVPSIP 1601
++ PG S + S P +P+ + S+ + ++ G T T P ++P
Sbjct: 627 TTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 686
Query: 1602 PLVQPVANVPAVQQTLIHSQPQPA---LLPNQPHTHCPEVDSDTQPKAPG------IDDI 1652
L Q + T HS P P L P + T PG + D
Sbjct: 687 GLSQ--------ESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDN 738
Query: 1653 KTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVT------------PGIPTTA---V 1697
T L + HSS+ + H ++S S + T P PTT V
Sbjct: 739 TTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFV 798
Query: 1698 APSKLLTSTTSTCLPPTNLPL-----GTVALPVTPVVTPGQVST---PVSTTTSGVKPGT 1749
PS + S+ +P T++ G V T +PG T P S TTSG +
Sbjct: 799 EPSTTSHGSPSS-IPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES 857
Query: 1750 APSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMI 1809
S T T L E P T + + R S
Sbjct: 858 TTSHSSTTHTISSAPST---TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 914
Query: 1810 TVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGA 1869
+ A G + + P T + + S + G + T+ G + S +
Sbjct: 915 SSQDATGTIVL--PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSS 972
Query: 1870 QKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTT 1929
+ A + S SE S S S P ST P+ T PG+ S H TT
Sbjct: 973 PRSPATTLSPASTT--SSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL------SRHSTT 1024
Query: 1930 ASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVL 1989
+ + T TTT+ + S + TDT A+
Sbjct: 1025 SHSSPGSTDTTLLPAS---TTTSGPSQESTTSHSSSGSTDT----------------ALS 1065
Query: 1990 PAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQS 2049
P + S H N P S F G S SS P LS +
Sbjct: 1066 PGSTTALSFGQESTTFHSN-PGSTHTTLFPDSTTSSGIVEA-STRVHSSTGSPRTTLSPA 1123
Query: 2050 LSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVP 2109
S S ++ E + H + E + Y +
Sbjct: 1124 SSTS-----------PGLQGESTAFQTHP-ASTHTTPSPPSTATAPVEESTTYHRSPGST 1171
Query: 2110 PAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQT--L 2167
P P ++ SG + T S + ++ + SG G+S S + P T
Sbjct: 1172 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR--GESTTSRISPGSTEIT 1229
Query: 2168 HPPGNIPESGQNQLLQPLKPSPSSDNLY---SAFTS--DGAISVPSLSAPGQGTSSTNTV 2222
PG+ G ++ SP S ++ TS G S S S PG T ST +
Sbjct: 1230 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG-STHSTVSP 1288
Query: 2223 GATVNSQAAQAQPPAMTSSRKGTFT 2247
+T ++ +SSR T T
Sbjct: 1289 ASTTTPGLSEESTTVYSSSRGSTET 1313
Score = 72.4 bits (176), Expect = 5e-12
Identities = 145/641 (22%), Positives = 231/641 (36%), Gaps = 98/641 (15%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
P P ++ + + T+S + F S R ES S VA +T S
Sbjct: 4483 PAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSS---PVATATTPS 4539
Query: 1290 PGMNLS----------HSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPF 1339
P + + HS+ + F E +T + S T T P
Sbjct: 4540 PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTT--SHSSTTHTISSAPST 4597
Query: 1340 LSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVP-TEEGIAGV----ATSTGVVT 1394
S++ PT+ ++ AT+ P+ +TS E T + + G A ST V
Sbjct: 4598 TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 4657
Query: 1395 SGGLPIPPVSESPVLSSVV-SSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTV 1453
G P+S + ++ + S T P + STT S T T+ SST L S
Sbjct: 4658 LGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEES 4717
Query: 1454 SATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSST 1513
+ +S + TP P A STT G V +T++ S+ ST
Sbjct: 4718 TTVHSSPVATATTPSP----------ARSTTSGL----VEESTAYHSS--------PGST 4755
Query: 1514 STPTLAETVVVSAHSLD-KTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVI 1572
T E+ S S + +TSHSSTT S PS++S+ +SY S PG +
Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTI--SSPPSTTSALVEEPTSYHSSPGSIATTHF 4813
Query: 1573 PSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVP----------AVQQTLIHSQP 1622
P ++ ++ S+P + +P + +++ TL +
Sbjct: 4814 PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTAT 4873
Query: 1623 QPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSL 1682
P L + D Q +P ++ + SL+S+ S+ S TS
Sbjct: 4874 TPGLSAKSTILYSSSRSPD-QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSG 4932
Query: 1683 VIESTVT----PGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPG---QVS 1735
+ + + T PG T ++P + TS+ + TP PG
Sbjct: 4933 LSQESTTFHSKPGSTETTLSPGSITTSSFAQEF-------------TTPHSQPGSALSTV 4979
Query: 1736 TPVSTTTSGV--KPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFP-GPSLTQSQQP 1792
+P STT G+ + T S P T+ + ++ S+Q PFP P T
Sbjct: 4980 SPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTM---SIHSQQSTPFPDSPGFT----- 5031
Query: 1793 LEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQP 1833
T+ P +T T +G S A ++ GT P
Sbjct: 5032 ---------HTVLPATLTTTD-IGQESTAFHSSSDATGTTP 5062
Score = 67.8 bits (164), Expect = 1e-10
Identities = 200/908 (22%), Positives = 314/908 (34%), Gaps = 128/908 (14%)
Query: 1365 DISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSE---SPVLSSVVSSITIPAV 1421
D ST+ SE + + G AT T + S V E SP+ S+ + + +P
Sbjct: 213 DSSTNSGHSEESTVSHSGPG--ATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPG- 269
Query: 1422 VSISTTSPSLQVPTST--SEIVVSSTALYPSVTVSA-TSASAGGSTATPGPKP------- 1471
STT+ L ++T S L P+ T S+ S + S + PGP
Sbjct: 270 ---STTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDS 326
Query: 1472 ---PAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSS---TSTPTLAETVVVS 1525
P V + A + G+T T++S T+ PS+ S SS T T L + S
Sbjct: 327 TTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTS 386
Query: 1526 AHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQA 1585
T S+TG + +PSSS++ +++ S P +S P
Sbjct: 387 GLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWP------------SSKDTSPAP 434
Query: 1586 AGPTSTPL-LPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQP 1644
+G TS + L P P + A TL HS+ + P P + T P
Sbjct: 435 SGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE------ESTPVHSSPVATATTPP 488
Query: 1645 KAPGIDDIKTLEEKLRSLFSEH-SSSGAQHASV-SLETSLVIESTVTPGIPTTAVAPSKL 1702
A RS S H S A H S S +T ES+ T G +
Sbjct: 489 PA-------------RSATSGHVEESTAYHRSPGSTQTMHFPESSTTSG------HSEES 529
Query: 1703 LTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVL 1762
T ST ++ P T AL T + + S G + +P
Sbjct: 530 ATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDA 589
Query: 1763 PVGTELPAGTLPSEQL-PPFPGPSLTQSQQPLEDLDAQLRRTLSPEMIT-VTSAVGPVSM 1820
T LPAG+ PS + P P + S + + + LS + T +S P +
Sbjct: 590 MATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTT 649
Query: 1821 AAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDA 1880
P ++T +G + S + G T+ G Q S A+ + G + +
Sbjct: 650 HLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS--PGPTDTTLS 707
Query: 1881 KSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPG-ISSDVPESAHKTTASEAKSDTGQ 1939
SS S P ST P+ T G + + +P + + S G
Sbjct: 708 PGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGS 767
Query: 1940 PTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKP 1999
T+ G +TT + + SK DT+ P + F+
Sbjct: 768 TTRQGE---STTFHS---WPSSK------DTRPAPPTTTSAFV----------------- 798
Query: 2000 ELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYM 2059
E S SH PSS P +R G + + S S + + +S + S
Sbjct: 799 EPSTTSH-GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES 857
Query: 2060 SSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAP 2119
++ + S + S E S ++ G P ++
Sbjct: 858 TTSHSSTTHT--------------ISSAPSTTSALVEEPTSYHSSPGST-ATTHFPDSST 902
Query: 2120 LSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLH--PQQTLHPPGNIPESG 2177
SGR T S S+ + + ++ + + L G+S S + +T PG+ G
Sbjct: 903 TSGRSEESTASHSSQDA-TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 961
Query: 2178 QNQLLQPLKPSPSS--DNLYSAFTSDGAI---SVPSLSAPGQG-----TSSTNTVGATVN 2227
++ SP S L A T+ + S S S PG ST T G + +
Sbjct: 962 LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRH 1021
Query: 2228 SQAAQAQP 2235
S + + P
Sbjct: 1022 STTSHSSP 1029
Score = 53.1 bits (126), Expect = 3e-06
Identities = 85/342 (24%), Positives = 133/342 (38%), Gaps = 52/342 (15%)
Query: 1228 KQPIPASSMPQQIG---IPTSSLTQ-------VVHSAGRRFIVSPVP-----ESRLRESK 1272
++P S P I P SS T HS+ ++P+P R+ ES
Sbjct: 4796 EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST 4855
Query: 1273 VF---PSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPN--FS 1327
F P + +T ASTA +PG++ + S + L A MT + P +S
Sbjct: 4856 TFYISPGSM-ETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS 4914
Query: 1328 HTGPTFPVVPPFLSSIAGVPTTAAATAPVPA---TSSPPNDISTSVIQSEVTVP-TEEGI 1383
T P ++ +G+ + P T+ P I+TS E T P ++ G
Sbjct: 4915 QAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGS 4974
Query: 1384 AGVATSTGVVTSGGLP--------IPPVSESPVLS-----SVVSSITIPAVVSISTTSPS 1430
A S T GL P +E+ S S+ S + P S T
Sbjct: 4975 ALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTV 5034
Query: 1431 LQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLT 1490
L +T++I STA + +S+ A G+T P P + G T
Sbjct: 5035 LPATLTTTDIGQESTAFH-------SSSDATGTT----PLPARSTASDLVGEPTTFYISP 5083
Query: 1491 SVSTTTSFPSTASQLSIQLSSST--STPTLAETVVVSAHSLD 1530
S + TT FP+++S + S+T ++P+ T +VS SL+
Sbjct: 5084 SPTYTTLFPASSSTSGLTEESTTFHTSPSFTST-IVSTESLE 5124
Score = 50.8 bits (120), Expect = 2e-05
Identities = 190/906 (20%), Positives = 296/906 (32%), Gaps = 141/906 (15%)
Query: 1430 SLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATL 1489
SL +P S + TV S +G S T + V+ G+TT +T
Sbjct: 129 SLGLPLSEQARAAGAREKERQETVINHSTFSGFSQITG-----STVNTSIGGNTTSASTP 183
Query: 1490 TSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSS 1549
+S T+F ++ ++ ST+T ++ S HS + T S G + PS
Sbjct: 184 SSSDPFTTFSDYGVSVTF-ITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSH 242
Query: 1550 SSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVAN 1609
S++ S ++ +P I S T LP G T+T L +
Sbjct: 243 SAT-----SVFVGEP---KTSPITSASMETTALP---GSTTTAGLSE------------- 278
Query: 1610 VPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSS 1669
+ T +S P+ S + + G+ + T + HS
Sbjct: 279 ----KSTTFYSSPRSP----------DRTLSPARTTSSGVSEKST---------TSHSRP 315
Query: 1670 GAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVV 1729
G H T +ST PG+ + A + ST +T P T P T
Sbjct: 316 GPTH------TIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHS 369
Query: 1730 TPGQVST---PVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSL 1786
+PG T P +TTTSG+ + P + T P TL P S
Sbjct: 370 SPGYTKTTRLPDNTTTSGLLEASTP----------VHSSTGSPHTTLS-------PSSST 412
Query: 1787 TQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVL 1846
T +P + SP TSA +S ++ + T
Sbjct: 413 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPT--------------- 457
Query: 1847 ATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVK 1906
T A +G + S + A+S S E S SP ST
Sbjct: 458 -THFSASSTTLGHSEESTPVHSSPVATATTPPPARSA--TSGHVEESTAYHRSPGSTQTM 514
Query: 1907 PEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDK 1966
P T G S + TT KS T P+ T+ + +G + D
Sbjct: 515 HFPESSTTSGHSEESATFHGSTT--HTKSST--PSTTAALAHTSYHSSLGSTETTHFRDS 570
Query: 1967 IT-DTKKEGPVASPPFMD-LEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVD 2024
T + E AS D + VLPA S PS L G S+ + S +
Sbjct: 571 STISGRSEESKASHSSPDAMATTVLPAG---------STPSVLVGDSTPSPISSGSMETT 621
Query: 2025 DGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHL 2084
GS P LS KS + +S + + M+S S E+ R H
Sbjct: 622 ALPGSTTKP-GLSEKSTTFYSSPRSPDTTHLPASMTSSGVS----EESTTSHSRPGSTHT 676
Query: 2085 KEIQDLQSRQKHEIESLYTKLGKVP-PAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGN 2143
+ ES + P + P + S T S ++L
Sbjct: 677 TAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLP 736
Query: 2144 KSPQLSGNLSGQSA--ASVLHPQQTLHPPGNIPESGQNQLL---------QPLKPSPSSD 2192
+ SG L +S P TL P G+ G++ +P P+ +S
Sbjct: 737 DNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA 796
Query: 2193 NLYSAFTSDGA-ISVPSLSAPGQGTSS-----TNTVGATVNSQAAQAQPPAMTSSRKGTF 2246
+ + TS G+ S+P+ + T+S + T ++ S P + T+S +G
Sbjct: 797 FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 856
Query: 2247 TDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKFSAPGQLCISMTSNLGGSAPIS 2306
+ H + A + + + + PG P +S G + S
Sbjct: 857 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD------SSTTSGRSEES 910
Query: 2307 AASATS 2312
AS +S
Sbjct: 911 TASHSS 916
Score = 42.0 bits (97), Expect = 0.007
Identities = 95/454 (20%), Positives = 152/454 (33%), Gaps = 36/454 (7%)
Query: 1887 SSTSESSVLSSSSPESTLVKPEPNGITIPGIS--SDVPESAHKTTASEAKSDTGQPTKVG 1944
S SE S S S P T P+ T+PG+S S S +T + T P+ +G
Sbjct: 302 SGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLG 361
Query: 1945 RFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEP 2004
+ TT + G ++ D T + AS P + + P EP
Sbjct: 362 P-ESTTFHSSPGYTKTTRLPDNTTTSGL--LEASTPVHSSTGSPHTTLSPSSSTTHEGEP 418
Query: 2005 SHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNE 2064
+ S + + + + S S P+ + S S + +S + +
Sbjct: 419 TTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHS 478
Query: 2065 SDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRR 2124
S + R H++E + Y + + P ++ SG
Sbjct: 479 SPVATATTPPPARSATSGHVEE------------STAYHRSPGSTQTMHFPESSTTSGHS 526
Query: 2125 RRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSAASVLHPQQTLHPPGNIPESGQNQLLQP 2184
GS + SS +P + L+ S S L +T H + SG+++ +
Sbjct: 527 EESATFHGSTTHTKSS----TPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKA 582
Query: 2185 LKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGATVNSQAAQAQPPAMTS---S 2241
SP + A T A S PS+ G T S + G S A P + T S
Sbjct: 583 SHSSPDA----MATTVLPAGSTPSVLV-GDSTPSPISSG----SMETTALPGSTTKPGLS 633
Query: 2242 RKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKFSAPGQLC---ISMTSN 2298
K T + D A S + ++ PG + PG +S S
Sbjct: 634 EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST 693
Query: 2299 LGGSAPISAASATSLGHFTKSMCPPQQYGFPATP 2332
S+P + S G T S P+ F + P
Sbjct: 694 ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP 727
Score = 39.3 bits (90), Expect = 0.047
Identities = 123/541 (22%), Positives = 193/541 (35%), Gaps = 86/541 (15%)
Query: 583 KQEESSLKQQVEQSSASQTGIKQLPSASTGI------PTASTTSASVSTQVEPEE---PE 633
+ EES+ SS TG LP+ ST T+ +S S+ T P P
Sbjct: 1989 RSEEST----ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 2044
Query: 634 ADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSY---GSQHEQAH-STGT 689
+ + P S T S + T S VS + T S+ GS H A + T
Sbjct: 2045 LSEKSTTFHSSPR----SPATTLSPAST---TSSGVSEESTTSHSRPGSTHTTAFPDSTT 2097
Query: 690 VPGHIPSTVQAQSQPHG----VYPPSSVAQGQSQGQPSSSSLTGVS-------SSQPIQH 738
PG + + S P + P S+ G SQ +S S G + S+ +
Sbjct: 2098 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF 2157
Query: 739 PQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPV 798
Q+ + T + S TS+ + + S +P+ P S
Sbjct: 2158 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS-------PASSTS 2210
Query: 799 PTIQGEPQI----PVATQPSVVPVHSGAHFLPVGQPLPTPLLP-QYPVSQIPIS--TPHV 851
P +QGE P +T + P + PV + P P + P S T
Sbjct: 2211 PGLQGESTAFQTHPASTHTTPSPPSTAT--APVEESTTYHRSPGSTPTTHFPASSTTSGH 2268
Query: 852 STAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLP-SQV 910
S T F S P A+G T +S+ +T + G ST S++ +T LP S
Sbjct: 2269 SEKSTIFHSSPD--ASGTTP-----SSAHSTTSGRGESTT--SRISPGSTEITTLPGSTT 2319
Query: 911 HPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVC 970
P L + + P + + +S L G PG ++ S V+
Sbjct: 2320 TPGLSEASTTFYSSPRS--PTTTLSPASMTSLGVGEESTTSRSQPGSTH----STVSPAS 2373
Query: 971 IHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTS 1030
+ LS T ++PG T V P P V G+ + + T
Sbjct: 2374 TTTPGLSEESTTVYSSSPGSTETTVFPRT------PTTSVRGEEPTTFHSRPASTHTTLF 2427
Query: 1031 SQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSS 1090
++ + +T G+++ + A P + A TQ P TL + + + + + PSSS
Sbjct: 2428 TEDS---TTSGLTEESTAFPGSPASTQTGLPATLTT----------ADLGEESTTFPSSS 2474
Query: 1091 G 1091
G
Sbjct: 2475 G 2475
Score = 35.0 bits (79), Expect = 0.88
Identities = 105/513 (20%), Positives = 165/513 (32%), Gaps = 82/513 (15%)
Query: 585 EESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVS-TQVEPEEPEADQHQQLQYQ 643
+ S+ + E+S+AS + Q + + +P STTS + + P + + L
Sbjct: 4622 DSSTTSGRSEESTASHSS--QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 4679
Query: 644 QPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHS----TGTVPGHIPSTVQ 699
+ + T SS T +S T+ + HS T T P ST
Sbjct: 4680 TTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 4739
Query: 700 AQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSL 759
+ Y SS Q+ P SS+ +G S H S
Sbjct: 4740 GLVEESTAYH-SSPGSTQTMHFPESSTASGRSEESRTSHS------------------ST 4780
Query: 760 SQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVH 819
+ T +S +TT+ V +P + P A P S T G + A+ S P
Sbjct: 4781 THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESS---TTSGRSEESTASHSS--PDT 4835
Query: 820 SGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASS 879
+G PLP H +T+ S ++ G + TLAS+
Sbjct: 4836 NGI------TPLPA----------------HFTTSGRIAESTTFYISPGSMET--TLAST 4871
Query: 880 ATTAAIPGVSTVVPSQLPT---LLQPVTQLPSQV--HPQLLQPAVQSMGIPANLGQAAEV 934
ATT + ST++ S + L P + S + P L +S A
Sbjct: 4872 ATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTS 4931
Query: 935 PLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTV 994
LS + P ++ ++P S S P L+T T
Sbjct: 4932 GLSQESTTFHSKPGST------ETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTT 4985
Query: 995 VQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVA 1054
V E + S PG + A + S+ ++ SQ + P +
Sbjct: 4986 VPGLSEESTTF----------YSSPGSTETTAFSHSNTMSI------HSQQSTPFPDSPG 5029
Query: 1055 QTQATQPTTLASSVDSAHSDVASGMSDGNENVP 1087
T P TL ++ S SD P
Sbjct: 5030 FTHTVLPATLTTTDIGQESTAFHSSSDATGTTP 5062
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 113 bits (282), Expect = 3e-24
Identities = 277/1264 (21%), Positives = 445/1264 (35%), Gaps = 214/1264 (16%)
Query: 651 SDGTVDSGQGSS-VFTESRVSSQQTVSYGSQHEQAHSTGTVPG--HIPSTVQAQSQPHGV 707
S T S G++ + TE ++ TV GS A ST G H+ +T +
Sbjct: 3711 STATPSSTPGTTWILTEPSTTATVTVPTGST-ATASSTQATAGTPHVSTTATTPTVTSSK 3769
Query: 708 YPPSSV--------AQGQSQGQPSSSSLTGVSSSQ------PIQHPQQQQGIQQTAPPQQ 753
P S A + P+++S T + SS + TA P
Sbjct: 3770 ATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSS 3829
Query: 754 TVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVP---TIQGEPQI--- 807
T + + + T ++ ATT + P P + ++P + T P
Sbjct: 3830 TPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTART 3889
Query: 808 -PVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMA 866
PV + P SG+ P P T + ++T ++T + T
Sbjct: 3890 PPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSS------TQT 3943
Query: 867 AGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPA 926
+G L+T A++ T ST PS P T +P + PA S +
Sbjct: 3944 SGTPPSLITTATTITATG----STTNPSSTPG----TTPIPPVLTTTATTPAATSSTVTP 3995
Query: 927 N--LGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTE- 983
+ LG P+ + G L P P A +S + + + P T
Sbjct: 3996 SSALGTTHTPPVPNTTATTHG--RSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH 4053
Query: 984 -VLATPGYF----PTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLES 1038
AT G P + P+ S G + PG + A + TT++
Sbjct: 4054 TPAATTGTTQHSTPALSSPHPSSRTTESPPSPG----TTTPGHTTATSRTTATATPSKTR 4109
Query: 1039 TQGVSQVAPAE-PVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRT 1097
T + +P P+ T +P A S +S G S G+ + S+ G
Sbjct: 4110 TSTLLPSSPTSAPITTVVTTGCEPQC-AWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAV 4168
Query: 1098 TKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLE----THNRKMV-----TFK 1148
++ R++++ P + + + +VVEC L+ NR+ V F
Sbjct: 4169 CEQPLGLECRAQAQ------PGVPLGELG----QVVECSLDFGLVCRNREQVGKFKMCFN 4218
Query: 1149 FDLD------GDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEG 1202
+++ G P AT + + + E+ A S + P
Sbjct: 4219 YEIRVFCCNYGHCPSTPAT----SSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSS 4274
Query: 1203 DQGL----ESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRF 1258
G + L + S K P A+++P + TS+ T+ ++
Sbjct: 4275 TPGTAPPPKVLTSPATTPTATSSKATSS-SSPRTATTLP----VLTSTATKSTATS---- 4325
Query: 1259 IVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEG 1318
V+P+P S L + P + T VA + P + +S L + R T
Sbjct: 4326 -VTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTST 4384
Query: 1319 PNTAPPNF----------SHTGPTFPVVPPFLSSIAG-------VPTTAAATAPVPATSS 1361
P++ P + T T P P SS G + TTA TA +T++
Sbjct: 4385 PSSTPGTTWILTELTTAATTTAATGPTATP--SSTPGTTWILTELTTTATTTASTGSTAT 4442
Query: 1362 PPNDISTSVIQSE------VTVPT--------EEGIAGV------ATSTGVVTSGGLPIP 1401
P + T+ I +E VTVPT + AG AT+ V +S P
Sbjct: 4443 PSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSS 4502
Query: 1402 PVSESPVLSSVVSSITIPAVVSIS----------------TTSP----SLQVPTSTSEIV 1441
+ L ++ S+ T P S + TT+P S P+ST E V
Sbjct: 4503 SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETV 4562
Query: 1442 VSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPST 1501
+ST L T +AT+ A GS ATP P + + +TT G T +T +S P T
Sbjct: 4563 HTSTVL----TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFT----ATPSSSPGT 4614
Query: 1502 ASQLSIQLSSSTSTPTLAETV---VVSAHSLDKTSH------SSTTGLAFSLSAPSSSSS 1552
A + +S++T+ T T V+ S+ T+H ++TT +A A SSS+
Sbjct: 4615 ALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSST 4674
Query: 1553 PGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTP-LLPQVPSIPPLVQPVANVP 1611
+G P + +T A G T+ P P I P++ A P
Sbjct: 4675 QTSGT---------------PPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTP 4719
Query: 1612 AVQQTLIHSQPQPALLPNQP----------HTHCPEVDSDTQPKAPGIDDIKTLEEKLRS 1661
A + S P P T + S T + T S
Sbjct: 4720 AATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMS 4779
Query: 1662 LFSEHSSSGAQHASVSLETSLVI-ESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGT 1720
S+ H S L T+ + +T + P++ + +++LT T+T T T
Sbjct: 4780 TIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTA-TTTAATGST 4838
Query: 1721 VALPVTPVVT-----PGQVSTPV----STTTSGVKPGTAPSKPPLTKAPVLPVGTELPAG 1771
L TP T P ++T + ST T+ GTA + +T +P T A
Sbjct: 4839 ATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTAT---AS 4895
Query: 1772 TLPS 1775
T+PS
Sbjct: 4896 TVPS 4899
Score = 108 bits (270), Expect = 6e-23
Identities = 268/1202 (22%), Positives = 424/1202 (35%), Gaps = 202/1202 (16%)
Query: 651 SDGTVDSGQGSS-VFTESRVSSQQTVSYGSQHEQAHSTGTVPG--HIPSTVQAQSQPHGV 707
S T S G++ + TE ++ TV GS A ST G H+ +T +
Sbjct: 2454 STATPSSTPGTTWILTEPSTTATVTVPTGST-ATASSTQATAGTPHVSTTATTPTVTSSK 2512
Query: 708 YPPSSV--------AQGQSQGQPSSSSLTGVSSSQ------PIQHPQQQQGIQQTAPPQQ 753
P S A + P+++S T + SS + TA P
Sbjct: 2513 ATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSS 2572
Query: 754 TVQYSLSQTSTSSEATT-------AQPVSQP---QAPQVLPQVSAGKQLPVSQPVPTIQG 803
T + + T ++ ATT A P S P +VL + G S T +
Sbjct: 2573 TPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTAR- 2631
Query: 804 EPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPI 863
+PV + P G+ P P T + ++T ++T +
Sbjct: 2632 --TLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSS------ 2683
Query: 864 TMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMG 923
T +G T P LT ++ATT G ST PS P T +P + PA S
Sbjct: 2684 TQTSG-TPPSLT--TTATTITATG-STTNPSSTPG----TTPIPPVLTTTATTPAATSST 2735
Query: 924 IPAN--LGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMP 981
+ + LG P+ + G L P P A +S + + + P
Sbjct: 2736 VTPSSALGTTHTPPVPNTTATTHG--RSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTG 2793
Query: 982 TE--VLATPGYF----PTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAV 1035
T AT G P + P+ S G + PG + A + TT++
Sbjct: 2794 TSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPG----TTTPGHTRATSRTTATATPS 2849
Query: 1036 LESTQGVSQVAPAE-PVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHE 1094
T + +P P+ T +P A S +S G S G+ + S+
Sbjct: 2850 KTRTSTLLPSSPTSAPITTVVTMGCEPQC-AWSEWLDYSYPMPGPSGGDFDTYSNIRAAG 2908
Query: 1095 GRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLE----THNRKMV-TFKF 1149
G ++ R++++ P + + + +VVEC L+ NR+ V FK
Sbjct: 2909 GAVCEQPLGLECRAQAQ------PGVPLRELG----QVVECSLDFGLVCRNREQVGKFKM 2958
Query: 1150 DLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESL 1209
+ EI N + S + + + G ++
Sbjct: 2959 CFN----YEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAI 3014
Query: 1210 QGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLT-QVVHSAGRRFIVS---PVPE 1265
+ L P SS P ++ T V+ S + + P+P
Sbjct: 3015 PSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPS 3074
Query: 1266 SRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPN 1325
L + P + T +A + P + +S L + R P++ P
Sbjct: 3075 FTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTP-- 3132
Query: 1326 FSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPND---ISTSVIQSEVTVPTEE- 1381
G T+ L+ + TT AAT P SS P ++ + VTVPT
Sbjct: 3133 ----GTTW-----ILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGST 3183
Query: 1382 ----------GIAGVATSTG----VVTSGGLPIPPVSESPVLSSVVSSITIPAVVSIS-- 1425
G V TST V++S P + L ++ S+ T P S++
Sbjct: 3184 ATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAI 3243
Query: 1426 --------------TTSP----SLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATP 1467
TT+P S P+ST E V +ST L T + T+ A GS ATP
Sbjct: 3244 PSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVL----TTTTTTTRATGSVATP 3299
Query: 1468 GPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSA- 1526
P + + +TT G T +T +S P TA + +S++T+ T TV S+
Sbjct: 3300 SSTPGTAHTTKVPTTTTTGFT----ATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSI 3355
Query: 1527 ----HSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPIL 1582
H+ + ++TT S++ PSSS+ P + +T
Sbjct: 3356 PGTTHTATVLTTTTTTVATGSMATPSSSTQTSG----------------TPPSLTTTATT 3399
Query: 1583 PQAAGPTSTP-LLPQVPSIPPLVQPVANVPAVQQTLI---------HSQPQP-------- 1624
A G T+ P P IPP++ A PA + + H+ P P
Sbjct: 3400 ITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHG 3459
Query: 1625 -ALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEH----SSSGAQHASVSLE 1679
+L P+ PHT V + GI + E S + H ++S QH++ +L
Sbjct: 3460 RSLPPSSPHT----VRTAWTSATSGILGTTHITEP--STVTSHTPAATTSTTQHSTPALS 3513
Query: 1680 ----TSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLP-----PTNLPLGTVALPVTPVVT 1730
+S ES +PG TT ++ + TT+T P T LP + P+T VVT
Sbjct: 3514 SPHPSSRTTESPPSPG--TTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVT 3571
Query: 1731 PG 1732
G
Sbjct: 3572 TG 3573
Score = 101 bits (252), Expect = 8e-21
Identities = 150/654 (22%), Positives = 234/654 (35%), Gaps = 91/654 (13%)
Query: 1275 PSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFP 1334
PS + A+ + +PG + + + + A + P TAPP
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPP---------- 3024
Query: 1335 VVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVT 1394
P L+S A PT ++ A ++SSP + V+ S T T + + T + T
Sbjct: 3025 --PKVLTSTATTPTATSSKAT--SSSSPRTATTLPVLTSTATKSTATSFTPIPSFT-LGT 3079
Query: 1395 SGGLPIPPVSESPVLSSVVSSIT-----IPAVVSISTTSPSLQVPTSTSEIVVSSTALYP 1449
+G LP + +S++ S T V++ T+ ST +T +
Sbjct: 3080 TGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILT 3139
Query: 1450 SVTVSATSASAGGSTATPGPKPPAV-VSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQ 1508
+T +AT+ +A G TATP P + + + + TV S +T +S +TA L +
Sbjct: 3140 ELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKV- 3198
Query: 1509 LSSSTSTPTLAETVVV------SAHSLDKTSHSSTTGLAFSLSA-PSSSSSPGAGVSSYI 1561
L+S+ +TPT+ + +A +L ++TT A S++A PSSS S
Sbjct: 3199 LTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQT 3258
Query: 1562 SQPGGLHPLVIPS----------VIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVP 1611
+ P PS V+ +T +A G +TP S P VP
Sbjct: 3259 TTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATP------SSTPGTAHTTKVP 3312
Query: 1612 AVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGA 1671
T + P + P T + + T P G S + S G
Sbjct: 3313 TTTTTGFTATPSSS--PGTALTPPVWISTTTTPTTRG------------STVTPSSIPGT 3358
Query: 1672 QHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTP 1731
H + L T+ TT VA + T ++ST T L T A T +
Sbjct: 3359 THTATVLTTT------------TTTVATGSMATPSSSTQTSGTPPSLTTTA---TTITAT 3403
Query: 1732 GQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTE---LPAGTLPSEQLPPFPGPSLTQ 1788
G + P ST PGT P P LT P T P+ L + PP P + T
Sbjct: 3404 GSTTNPSST------PGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATT 3457
Query: 1789 SQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLAT 1848
+ L SP + + T ITE T + +T
Sbjct: 3458 HGRSLP--------PSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHST 3509
Query: 1849 SSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPES 1902
+ + R S + G G + + S + +S L SSP S
Sbjct: 3510 PALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTS 3563
Score = 101 bits (251), Expect = 1e-20
Identities = 119/458 (25%), Positives = 188/458 (41%), Gaps = 68/458 (14%)
Query: 1313 AQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQ 1372
A TE + S G T+ + P ++ VPT + ATA ++ +ST+
Sbjct: 2446 ATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT 2505
Query: 1373 SEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVL---SSVVSSITIPAVVSISTTSP 1429
VT + T+T + P + S SS+ ++ T + + T +
Sbjct: 2506 PTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 2565
Query: 1430 SLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATL 1489
S P+ST E V +ST L T +AT+ A GS ATP P + + +TT G T
Sbjct: 2566 STATPSSTPETVHTSTVL----TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFT- 2620
Query: 1490 TSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSH------SSTTGLAFS 1543
+T +S P TA L + +S++T+ T TV S S+ T+H ++TT +A
Sbjct: 2621 ---ATPSSSPGTARTLPVWISTTTTPTTRGSTVTPS--SIPGTTHTPTVLTTTTTTVATG 2675
Query: 1544 LSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTP-LLPQVPSIPP 1602
A SSS+ +G P + +T A G T+ P P IPP
Sbjct: 2676 SMATPSSSTQTSGT---------------PPSLTTTATTITATGSTTNPSSTPGTTPIPP 2720
Query: 1603 LVQPVANVPAVQQTLI---------HSQPQP---------ALLPNQPHTHCPEVDSDTQP 1644
++ A PA + + H+ P P +L P+ PHT S T
Sbjct: 2721 VLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSAT-- 2778
Query: 1645 KAPGIDDIKTLEEKLRSLFSEHSSSG-AQHASVSLE----TSLVIESTVTPGIPTTAVAP 1699
+ + E + + +++G QH++ +L +S ES +PG TT
Sbjct: 2779 -SGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPG--TTTPGH 2835
Query: 1700 SKLLTSTTSTCLP-----PTNLPLGTVALPVTPVVTPG 1732
++ + TT+T P T LP + P+T VVT G
Sbjct: 2836 TRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMG 2873
Score = 99.4 bits (246), Expect = 4e-20
Identities = 178/738 (24%), Positives = 277/738 (37%), Gaps = 104/738 (14%)
Query: 1313 AQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQ 1372
A TE + S G T+ + P ++ VPT + ATA ++ +ST+
Sbjct: 3703 ATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT 3762
Query: 1373 SEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVL---SSVVSSITIPAVVSISTTSP 1429
VT + T+T + P + S SS+ ++ T + + T +
Sbjct: 3763 PTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 3822
Query: 1430 SLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATL 1489
S P+ST E +ST L T +AT+ A GS ATP P + + +TT G T+
Sbjct: 3823 STATPSSTPETAHTSTVL----TTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTV 3878
Query: 1490 TSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSA-----HSLDKTSHSSTTGLAFSL 1544
T +S P TA + +S++T+ T TV S+ H+ + ++TT S+
Sbjct: 3879 ----TPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM 3934
Query: 1545 SAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTP-LLPQVPSIPPL 1603
+ PSSS +Q G P +I + T A G T+ P P IPP+
Sbjct: 3935 ATPSSS-----------TQTSGTPPSLITTATTIT-----ATGSTTNPSSTPGTTPIPPV 3978
Query: 1604 VQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLF 1663
+ A PA + + P AL TH P V + T T + S
Sbjct: 3979 LTTTATTPAATSSTV--TPSSAL----GTTHTPPVPNTT----------ATTHGRSLSPS 4022
Query: 1664 SEHSSSGAQHASVS--LETSLVIE-STVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGT 1720
S H+ A ++ S L T+ + E ST T P ++ T S+ P + T
Sbjct: 4023 SPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR----T 4078
Query: 1721 VALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPV-LPVGTELPAGTLP----S 1775
P +P T +T S TT+ P + L +P P+ T + G P S
Sbjct: 4079 TESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWS 4138
Query: 1776 EQLP---PFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQ 1832
E L P PGPS D + +R A G P + E Q
Sbjct: 4139 EWLDYSYPMPGPSGGDF-----DTYSNIR------------AAGGAVCEQPLGL-ECRAQ 4180
Query: 1833 PQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHF----ESS 1888
Q GV + G V+ S G+ R QV G K N ++ +
Sbjct: 4181 AQPGVPLGELGQVVECSLDFGLVCRNREQV-----GKFKMCFNYEIRVFCCNYGHCPSTP 4235
Query: 1889 TSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQV 1948
+ S+ + SS+P +T + +T ++ S T + T P KV
Sbjct: 4236 ATSSTAMPSSTPGTTWI------LTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPA 4289
Query: 1949 TT---TANKVGRFSVSKTEDK---ITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELS 2002
TT T++K S +T +T T + S + +P++ ++
Sbjct: 4290 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVA 4349
Query: 2003 EPSHLNGPSSDPEAAFLS 2020
S ++ PSS PE S
Sbjct: 4350 TMSTIH-PSSTPETTHTS 4366
Score = 94.0 bits (232), Expect = 2e-18
Identities = 117/452 (25%), Positives = 181/452 (40%), Gaps = 70/452 (15%)
Query: 1320 NTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAAT-APVPATSSPPNDISTSVIQSEVTVP 1378
+TA P+ S G T+ + P ++ T + AT T+ PP ++T+ VT
Sbjct: 1896 STATPS-STPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSS 1954
Query: 1379 --TEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSI-TIPAVVSISTTSPSLQVPT 1435
T G AT+ + S S +P+ SS + + T + + T + S P+
Sbjct: 1955 KATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPS 2014
Query: 1436 STSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTT 1495
ST E +ST L T +AT+ A GS ATP P + + +TT G T +T
Sbjct: 2015 STPETAHTSTVL----TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFT----ATP 2066
Query: 1496 TSFPSTASQLSIQLSSSTSTPTLAETVVVSA-----HSLDKTSHSSTTGLAFSLSAPSSS 1550
+S P TA + +S++T+ T TV S+ H+ + ++TT S++ PSSS
Sbjct: 2067 SSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSS 2126
Query: 1551 SSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTP-LLPQVPSIPPLVQPVAN 1609
+ P + +T A G T+ P P IPP++ A
Sbjct: 2127 TQTSG----------------TPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 2170
Query: 1610 VPAVQQTLI---------HSQPQP---------ALLPNQPHTHCPEVDSDTQPKAPGIDD 1651
PA + H+ P P +L P+ PHT V + GI
Sbjct: 2171 TPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHT----VRTAWTSATSGILG 2226
Query: 1652 IKTLEEKLRSLFSEH----SSSGAQHASVSLE----TSLVIESTVTPGIPT---TAVAPS 1700
+ E S + H ++ QH++ +L +S ES +PG T T
Sbjct: 2227 TTHITEP--STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSR 2284
Query: 1701 KLLTSTTSTCLPPTNLPLGTVALPVTPVVTPG 1732
T+T S T LP + P+T VVT G
Sbjct: 2285 TTATATPSKTRTSTLLPSSPTSAPITTVVTMG 2316
Score = 80.5 bits (197), Expect = 2e-14
Identities = 117/479 (24%), Positives = 172/479 (35%), Gaps = 80/479 (16%)
Query: 1435 TSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPK-----PPAVVSQQAAGSTTVGATL 1489
T+T +T + T +AT+ ++ GSTATP PP V++ A T
Sbjct: 1897 TATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVT---- 1952
Query: 1490 TSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKT--SHSSTTGLAFSLSAP 1547
+S +T +S P TA+ L L S+ +TPT + + SL T S TT ++S
Sbjct: 1953 SSKATPSSSPGTATALPA-LRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTA 2011
Query: 1548 SSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPV 1607
+ SS+P +S +V+ +T A G +TP S P
Sbjct: 2012 TPSSTPETAHTS--------------TVLTATATTTGATGSVATP------SSTPGTAHT 2051
Query: 1608 ANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHS 1667
VP T + P + P T + + T P G S + S
Sbjct: 2052 TKVPTTTTTGFTATPSSS--PGTALTPPVWISTTTTPTTRG------------STVTPSS 2097
Query: 1668 SSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTP 1727
G H + L T+ TT VA + T ++ST T L T A T
Sbjct: 2098 IPGTTHTATVLTTT------------TTTVATGSMATPSSSTQTSGTPPSLTTTA---TT 2142
Query: 1728 VVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTE---LPAGTLPSEQLPPFPGP 1784
+ G + P ST PGT P P LT P T P+ L + PP P
Sbjct: 2143 ITATGSTTNPSST------PGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNT 2196
Query: 1785 SLTQSQQPLEDLDAQLRRTLSPEMITVTSAV-GPVSMAAPTAITEAGTQPQKGVSQVKEG 1843
T + L RT + TS + G + P+ +T G +Q
Sbjct: 2197 MATTHGRSLPPSSPHTVRT---AWTSATSGILGTTHITEPSTVTSHTLAATTGTTQ-HST 2252
Query: 1844 PVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPES 1902
P L++ + R S + G G + + S + +S L SSP S
Sbjct: 2253 PALSSPHPS-----SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTS 2306
Score = 80.1 bits (196), Expect = 2e-14
Identities = 186/875 (21%), Positives = 311/875 (35%), Gaps = 136/875 (15%)
Query: 1232 PASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPG 1291
P+SS +P T +A V+P+P S L + S+ T A + +P
Sbjct: 1958 PSSSPGTATALPALRSTATTPTATS---VTPIPSSSLGTTWTRLSQTTTPTATMSTATPS 2014
Query: 1292 M--NLSHSASSL-----------SLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFP---V 1335
+H+++ L S+ S A T+ P T F+ T + P +
Sbjct: 2015 STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 2074
Query: 1336 VPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTS 1395
PP S PTT +T SS P T+ + + T G +AT + +
Sbjct: 2075 TPPVWISTTTTPTTRGSTV---TPSSIPGTTHTATVLTTTTTTVATG--SMATPSSSTQT 2129
Query: 1396 GGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTV-S 1454
G P P L++ ++IT STT+PS T+ V+++TA P+ T +
Sbjct: 2130 SGTP-------PSLTTTATTITATG----STTNPSSTPGTTPIPPVLTTTATTPAATSNT 2178
Query: 1455 ATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTS 1514
T +SA G+T TP P P + +TT G +L PS+ + +S+TS
Sbjct: 2179 VTPSSALGTTHTP-PVPNTM-------ATTHGRSLP--------PSSPHTVRTAWTSATS 2222
Query: 1515 ----TPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPL 1570
T + E V++H+L ++TTG + SS P + + PG P
Sbjct: 2223 GILGTTHITEPSTVTSHTL-----AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 2277
Query: 1571 VIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVA----NVPAVQQTLIHSQPQPAL 1626
+ +T + TST LLP P+ P+ V A + L +S P P
Sbjct: 2278 HTTATSRTTATATPSKTRTST-LLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGP 2336
Query: 1627 LPNQPHTHCP---------------EVDSDTQPKAPGIDDIKTLE--------------- 1656
T+ E + QP P + + +E
Sbjct: 2337 SGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQV 2396
Query: 1657 EKLRSLFS----------EHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTST 1706
K + F+ H S +S ++ +S + + + TTA ++
Sbjct: 2397 GKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTA 2456
Query: 1707 TSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKP--GTAPSKPPLTKAPVLPV 1764
T + P T L + T V G +T ST + P T + P +T + P
Sbjct: 2457 TPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPF 2516
Query: 1765 GTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLD---AQLRRTLSP--EMITVTSAVGPVS 1819
+ A LP+ + + + + P L +L +T +P M T T + P +
Sbjct: 2517 SSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET 2576
Query: 1820 MAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSED 1879
+ T +T T + G V SS G + ++ G +
Sbjct: 2577 VHTSTVLTTTAT------TTGATGSVATPSSTPGTAHTTKV-LTTTTTGFTATPSSSPGT 2629
Query: 1880 AKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQ 1939
A+++ ST+ + S+ + + + T+ ++ + T S + +G
Sbjct: 2630 ARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGT 2689
Query: 1940 PTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKP 1999
P +TTTA +++ T + G PP + A PA
Sbjct: 2690 PP-----SLTTTAT-----TITATGSTTNPSSTPGTTPIPPVL-TTTATTPAA-----TS 2733
Query: 2000 ELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPH 2034
PS G + P + S SP SPH
Sbjct: 2734 STVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPH 2768
Score = 78.6 bits (192), Expect = 7e-14
Identities = 118/527 (22%), Positives = 179/527 (33%), Gaps = 87/527 (16%)
Query: 1385 GVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSS 1444
G ST +S P S +P + +++ +T A + ST S T+T +
Sbjct: 3672 GHCPSTPATSSTATP----SSTPGTTWILTKLTTTATTTESTGS------TATPSSTPGT 3721
Query: 1445 TALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQ 1504
T + + +AT GSTAT + + + T +S +T S P TA+
Sbjct: 3722 TWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATA 3781
Query: 1505 LSIQLSSSTSTPTLAETVVVSAHSLDKT--SHSSTTGLAFSLSAPSSSSSPGAGVSSYIS 1562
L L S+ +TPT + + SL T S TT ++S + SS+P +S
Sbjct: 3782 LPA-LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTS--- 3837
Query: 1563 QPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQP 1622
+V+ +T +A G +TP S P VP T P
Sbjct: 3838 -----------TVLTTTATTTRATGSVATP------SSTPGTAHTTKVPTTTTTGFTVTP 3880
Query: 1623 QPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSL 1682
+ P T + + T P G
Sbjct: 3881 SSS--PGTARTPPVWISTTTTPTTSG---------------------------------- 3904
Query: 1683 VIESTVTPG-IPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTP---VVTPGQVSTPV 1738
STVTP +P T P+ L T+TT+ P + TP + T ++
Sbjct: 3905 ---STVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATG 3961
Query: 1739 STTTSGVKPGTAPSKPPLTKAPVLPVGTE---LPAGTLPSEQLPPFPGPSLTQSQQPLED 1795
STT PGT P P LT P T P+ L + PP P + T + L
Sbjct: 3962 STTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSP 4021
Query: 1796 LDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVF 1855
RT + +G + P+ T G +Q P L++ +
Sbjct: 4022 SSPHTVRTAWTS--ATSGTLGTTHITEPSTGTSHTPAATTGTTQ-HSTPALSSPHPS--- 4075
Query: 1856 KMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPES 1902
R S + G G + + S + +S L SSP S
Sbjct: 4076 --SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTS 4120
Score = 76.3 bits (186), Expect = 3e-13
Identities = 118/523 (22%), Positives = 181/523 (34%), Gaps = 79/523 (15%)
Query: 1385 GVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSS 1444
G ST +S +P S +P + +++ +T A + ST S T+T +
Sbjct: 2415 GHCPSTPATSSTAMP----SSTPGTTWILTELTTTATTTESTGS------TATPSSTPGT 2464
Query: 1445 TALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQ 1504
T + + +AT GSTAT + + + T +S +T S P TA+
Sbjct: 2465 TWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATA 2524
Query: 1505 LSIQLSSSTSTPTLAETVVVSAHSLDK--TSHSSTTGLAFSLSAPSSSSSPGAGVSSYIS 1562
L L S+ +TPT + + SL T S TT ++S + SS+P +S
Sbjct: 2525 LP-ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTS--- 2580
Query: 1563 QPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQP 1622
V+ + +T A P+STP + + T
Sbjct: 2581 -------TVLTTTATTTGATGSVATPSSTPGTAHTTKV------------LTTTTTGFTA 2621
Query: 1623 QPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSL 1682
P+ P T + + T P G S + S G H L T+
Sbjct: 2622 TPSSSPGTARTLPVWISTTTTPTTRG------------STVTPSSIPGTTHTPTVLTTT- 2668
Query: 1683 VIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTT 1742
TT VA + T ++ST T L T A T + G + P ST
Sbjct: 2669 -----------TTTVATGSMATPSSSTQTSGTPPSLTTTA---TTITATGSTTNPSST-- 2712
Query: 1743 SGVKPGTAPSKPPLTKAPVLPVGTE---LPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQ 1799
PGT P P LT P T P+ L + PP P + T + L
Sbjct: 2713 ----PGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPH 2768
Query: 1800 LRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGR 1859
RT + +G + P+ T G +Q P L++ + R
Sbjct: 2769 TVRTAWTS--ATSGTLGTTHITEPSTGTSHTPAATTGTTQ-HSTPALSSPHPS-----SR 2820
Query: 1860 FQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPES 1902
S + G G ++ + S + +S L SSP S
Sbjct: 2821 TTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTS 2863
Score = 75.5 bits (184), Expect = 6e-13
Identities = 125/476 (26%), Positives = 186/476 (39%), Gaps = 85/476 (17%)
Query: 1357 PATSS---PPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVV 1413
PATSS P + T+ I +E+T T+T ++G P S +P + ++
Sbjct: 2421 PATSSTAMPSSTPGTTWILTELTT----------TATTTESTGSTATP--SSTPGTTWIL 2468
Query: 1414 SSITIPAVVSIST----TSPSLQVPTSTSEIVVSSTALYPSVTVSATS--ASAGGSTATP 1467
+ + A V++ T T+ S Q T VS+TA P+VT S + +S G +TA P
Sbjct: 2469 TEPSTTATVTVPTGSTATASSTQATAGTPH--VSTTATTPTVTSSKATPFSSPGTATALP 2526
Query: 1468 GPK----PPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVV 1523
+ P S A S+++G T T +S TT+ +T S ++ +STP T
Sbjct: 2527 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMS-----TATPSSTPETVHTST 2581
Query: 1524 VSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYI-------------SQPGGLHPL 1570
V T+ ++TTG S++ P SS+PG ++ + S PG L
Sbjct: 2582 V------LTTTATTTGATGSVATP--SSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTL 2633
Query: 1571 VI-------PSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQ 1623
+ P+ ST G T TP + + +A + QT S
Sbjct: 2634 PVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQT---SGTP 2690
Query: 1624 PAL------LPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHA-SV 1676
P+L + T P T P P + T S + S+ G H V
Sbjct: 2691 PSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 2750
Query: 1677 SLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPG--QV 1734
T+ +++P P T TS TS L T++ + TP T G Q
Sbjct: 2751 PNTTATTHGRSLSPSSPHTV---RTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 2807
Query: 1735 STPV--------STTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFP 1782
STP TT S PGT + P T+A T P+ T S LP P
Sbjct: 2808 STPALSSPHPSSRTTESPPSPGT--TTPGHTRATSRTTATATPSKTRTSTLLPSSP 2861
Score = 73.6 bits (179), Expect = 2e-12
Identities = 132/537 (24%), Positives = 191/537 (35%), Gaps = 109/537 (20%)
Query: 1434 PTSTSEIVVSSTA----LYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATL 1489
P ++S + SST + +T +AT+ + GSTATP P STT T+
Sbjct: 2421 PATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPS-STPGTTWILTEPSTTATVTV 2479
Query: 1490 TSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSA-PS 1548
+ ST T+ + A+ + +S++ +TPT+ + K + S+ G A +L A S
Sbjct: 2480 PTGSTATASSTQATAGTPHVSTTATTPTVTSS---------KATPFSSPGTATALPALRS 2530
Query: 1549 SSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQP-- 1606
++++P A +S+ + P S+ + L Q PT+T S P V
Sbjct: 2531 TATTPTA--TSFTAIPSS-------SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTST 2581
Query: 1607 VANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEH 1666
V A S P+ P HT K L +
Sbjct: 2582 VLTTTATTTGATGSVATPSSTPGTAHT------------------TKVLTTTTTGFTATP 2623
Query: 1667 SSSGAQHASVSLETSLVIE-----STVTPG-IPTTAVAPSKLLTSTTSTCLPPTNLPLGT 1720
SSS ++ + S STVTP IP T P+ L T+TT+ P +
Sbjct: 2624 SSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSS 2683
Query: 1721 VALPVTP---VVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTE---LPAGTLP 1774
TP T ++ STT PGT P P LT P T P+ L
Sbjct: 2684 TQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALG 2743
Query: 1775 SEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMI-TVTSAVGPVSMAAPTAITEAGTQP 1833
+ PP P + T R+LSP TV +A S + T T T+P
Sbjct: 2744 TTHTPPVPNTTATTHG-----------RSLSPSSPHTVRTAW--TSATSGTLGTTHITEP 2790
Query: 1834 QKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESS 1893
G S P T G Q S A S H S T+ES
Sbjct: 2791 STGTSHT---PAATT---------GTTQHSTPA-------------LSSPHPSSRTTES- 2824
Query: 1894 VLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTT 1950
P G T PG + + T S+ ++ T P+ +TT
Sbjct: 2825 -------------PPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITT 2868
Score = 70.5 bits (171), Expect = 2e-11
Identities = 90/370 (24%), Positives = 146/370 (39%), Gaps = 31/370 (8%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
P A + P I T+ T ++G S +P + ++V + T TVA + +
Sbjct: 4612 PGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTT-HTARVLTTTTT-TVATGSMAT 4669
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTT 1349
P + S + SL + + T P++ P T P+ P S+ TT
Sbjct: 4670 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPG-------TTPITPVLTSTA----TT 4718
Query: 1350 AAATAPVPATSSPPNDIST-SVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPV 1408
AAT+ +SS P +T V+ S T T + +ST + T+ +P +
Sbjct: 4719 PAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSST-LWTTWTVPAQTTTPMST 4777
Query: 1409 LSSVVSSIT-----IPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGS 1463
+S++ +S T V++ + T T+T + +T + +T +AT+ +A GS
Sbjct: 4778 MSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGS 4837
Query: 1464 TATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVV 1523
TAT P TT T S T P+ ++ + + TP + T+
Sbjct: 4838 TATLSSTP----------GTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMA 4887
Query: 1524 VSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQP-GGLHPLVIPSVIASTPIL 1582
+ T SS+T A SS P VS+ S L P PS STP
Sbjct: 4888 TMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCF 4947
Query: 1583 PQAAGPTSTP 1592
+A G +P
Sbjct: 4948 CRAFGQFFSP 4957
Score = 56.6 bits (135), Expect = 3e-07
Identities = 139/578 (24%), Positives = 197/578 (34%), Gaps = 121/578 (20%)
Query: 1457 SASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTT-SFPSTASQLSIQ------- 1508
S A STA P P G+T + LT+ +TTT S STA+ S
Sbjct: 4233 STPATSSTAMPSSTP---------GTTWILTELTTTATTTASTGSTATPSSTPGTAPPPK 4283
Query: 1509 -LSSSTSTPTLAETVVVSAHS------LDKTSHSSTTGLAFSLSAPSSSSSPGAG----- 1556
L+S +TPT + S+ S L + ++T A S++ SS+ G
Sbjct: 4284 VLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQ 4343
Query: 1557 VSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPP--------LVQPVA 1608
++ ++ +HP P ++ +L A T PS P L
Sbjct: 4344 TTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAAT 4403
Query: 1609 NVPAVQQTLIHSQPQPAL-----LPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSL- 1662
A T S L T + T PG I T ++
Sbjct: 4404 TTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT 4463
Query: 1663 ---------FSEHSSSGAQHASVSLETSLVIESTVTP-GIPTTAVA-PSKLLTSTTSTCL 1711
S +++G H S + T V S TP P TA A P+ T+TT T
Sbjct: 4464 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTAT 4523
Query: 1712 PPTNLP---LGTVALPVTPVVTPGQV-------STPVSTTTSGVKPGTA----------- 1750
T +P LGT ++ TP STP + TS V TA
Sbjct: 4524 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVAT 4583
Query: 1751 PSKPP---------------LTKAPVLPVGTEL------PAGTLPSEQLPPFPGPSLTQS 1789
PS P T P GT L T P+ P G ++T S
Sbjct: 4584 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPS 4643
Query: 1790 QQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITE-AGTQPQ---KGVSQVKEGPV 1845
P A++ + T T+ V SMA P++ T+ +GT P + G
Sbjct: 4644 SIPGTTHTARV-------LTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 4696
Query: 1846 LATSSGAGVFKMGRFQVSVAADGAQKEGKNKSED----AKSVHFESSTSESSVLSSSS-- 1899
SS G + S A A K S A ++ +ST+ S +S +
Sbjct: 4697 TNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPI 4756
Query: 1900 PESTL--VKPEPNGITIPGI------SSDVPESAHKTT 1929
P STL P T P +S PE+ H +T
Sbjct: 4757 PSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTST 4794
Score = 53.1 bits (126), Expect = 3e-06
Identities = 97/442 (21%), Positives = 147/442 (33%), Gaps = 75/442 (16%)
Query: 692 GHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGI-----Q 746
GH PST S PSS +++ T S+ P G +
Sbjct: 3672 GHCPSTPATSSTA----TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTE 3727
Query: 747 QTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQP-----VPTI 801
+ TV + T++S++AT P A P V++ K P S P +P +
Sbjct: 3728 PSTTATVTVPTGSTATASSTQATAGTPHVSTTA--TTPTVTSSKATPFSSPGTATALPAL 3785
Query: 802 QGEPQIPVATQPSVVPVHS-GAHFLPVGQ-PLPTPLLPQYPVSQIP-------------- 845
+ P AT + +P S G + + Q PT + S P
Sbjct: 3786 RSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTAT 3845
Query: 846 -------ISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGV---------- 888
++TP + + +P T G T +T +SS TA P V
Sbjct: 3846 TTRATGSVATPSSTPGTAHTTKVPTTTTTGFT---VTPSSSPGTARTPPVWISTTTTPTT 3902
Query: 889 --STVVPSQL------PTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGD 940
STV PS + PT+L T + + Q+ G P +L A ++G
Sbjct: 3903 SGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGS 3962
Query: 941 VLYQGFPPRLPPQYP-----GDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVV 995
P P P + A SS V T +PP+P T G +
Sbjct: 3963 TTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPS 4022
Query: 996 QPY-VESNLLVPMGGVGGQVQVSQPGGSLAQAP-----TTSSQQAVLESTQGVSQVAPAE 1049
P+ V + G G +++P + P TT L S S+ +
Sbjct: 4023 SPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESP 4082
Query: 1050 P----VAVAQTQATQPTTLASS 1067
P T AT TT ++
Sbjct: 4083 PSPGTTTPGHTTATSRTTATAT 4104
Score = 53.1 bits (126), Expect = 3e-06
Identities = 102/511 (19%), Positives = 178/511 (34%), Gaps = 79/511 (15%)
Query: 596 SSASQTGIKQLPSASTG----IPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVL- 650
+ ++ T + +PS++ G +P +TT + + + P H + +
Sbjct: 4319 TKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRA 4378
Query: 651 --SDGTVDSGQGSS-VFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGV 707
S T S G++ + TE ++ T + G + + GT T A
Sbjct: 4379 TSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTA------- 4431
Query: 708 YPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSE 767
++ A S PSS+ T ++P + TV + T++S++
Sbjct: 4432 ---TTTASTGSTATPSSTPGTTWILTEP------------STTATVTVPTGSTATASSTQ 4476
Query: 768 ATTAQPVSQPQAPQVLPQVSAGKQLPVSQP-----VPTIQGEPQIPVATQPSVVPVHS-G 821
AT P A P V++ K P S P +P ++ P AT + +P S G
Sbjct: 4477 ATAGTPHVSTTA--TTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLG 4534
Query: 822 AHFLPVGQPL-PTPLLPQYPVSQIPISTPHVSTAQTGF-------------SSLPITMAA 867
+ + Q PT + S P T H ST T SS P T
Sbjct: 4535 TTWTRLSQTTTPTATMSTATPSSTP-ETVHTSTVLTATATTTGATGSVATPSSTPGTAHT 4593
Query: 868 GITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPAN 927
T +AT ++ PG + P + T P T P+ + ++ A
Sbjct: 4594 TKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTAR 4653
Query: 928 LGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLAT 987
+ +++G + P S PS + +T+ + T +T
Sbjct: 4654 VLTTTTTTVATGSM-------ATPSSSTQTSGTPPSLTTTA----TTITATGSTTNPSST 4702
Query: 988 PGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVA- 1046
PG P + P + S P + + + +P T++ VL ST S
Sbjct: 4703 PGTTP--ITPVLTSTATTP--------AATSSKATSSSSPRTATTLPVLTSTATKSTATS 4752
Query: 1047 ----PAEPVAVAQTQATQPTTLASSVDSAHS 1073
P+ + T Q TT S++ + H+
Sbjct: 4753 FTPIPSSTLWTTWTVPAQTTTPMSTMSTIHT 4783
Score = 45.1 bits (105), Expect = 9e-04
Identities = 123/567 (21%), Positives = 187/567 (32%), Gaps = 124/567 (21%)
Query: 596 SSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLS-DGT 654
S+A+ + + ST + T +TT+ + + P H + P+ + T
Sbjct: 3266 STATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTT---KVPTTTTTGFTAT 3322
Query: 655 VDSGQGSSVFTESRVSSQQT-VSYGSQHEQAHSTGTV-PGHIPSTVQAQSQPHGVYPPSS 712
S G+++ +S+ T + GS + GT + +T + PSS
Sbjct: 3323 PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSS 3382
Query: 713 VAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQ 772
Q +++ T ++++ +P G P T + + +TSS T +
Sbjct: 3383 STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTT--ATTPAATSSTVTPSS 3440
Query: 773 PVSQPQAPQVLPQVSA---GKQLPVSQP----------VPTIQGEPQIPVATQPSVVPVH 819
+ P V P +A G+ LP S P I G I T+PS V H
Sbjct: 3441 ALGTTHTPPV-PNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI---TEPSTVTSH 3496
Query: 820 SGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASS 879
+ P T Q+ S +S+PH S+ T P G T P T +S
Sbjct: 3497 T---------PAATTSTTQH--STPALSSPHPSSRTTESPPSP-----GTTTPGHTRGTS 3540
Query: 880 ATTA-AIPG---VSTVVPSQLPTLLQPVTQLPSQVHPQLL-------------------- 915
TTA A P ST++PS PT T + + PQ
Sbjct: 3541 RTTATATPSKTRTSTLLPSS-PTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFD 3599
Query: 916 --------------QP------AVQSMGIP-ANLGQAAEVPLSSGDVLYQ---------- 944
QP A G+P LGQ E L G V
Sbjct: 3600 TYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMC 3659
Query: 945 ------------GFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVL------- 985
G P P S PSS + I + + + TE
Sbjct: 3660 FNYEIRVFCCNYGHCPSTPAT---SSTATPSSTPGTTWILTKLTTTATTTESTGSTATPS 3716
Query: 986 ATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGG-----SLAQAPTTSSQQAVLESTQ 1040
+TPG + +P + + VP G G + A PT +S +A S+
Sbjct: 3717 STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSP 3776
Query: 1041 GVSQVAPAEPVAVAQTQATQPTTLASS 1067
G + PA AT T + SS
Sbjct: 3777 GTATALPALRSTATTPTATSFTAIPSS 3803
Score = 44.3 bits (103), Expect = 0.001
Identities = 131/653 (20%), Positives = 208/653 (31%), Gaps = 143/653 (21%)
Query: 1471 PPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLD 1530
PP + A +TT A ++ T+S T + + S+T+ PTL+E + ++
Sbjct: 1613 PPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPA----STTAVPTLSEGLTSPRYT-- 1666
Query: 1531 KTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQ---PG----------GLHPLVIPSVIA 1577
T ++TTG + + + + PG S+ ++ PG P + P+ +A
Sbjct: 1667 STLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMA 1726
Query: 1578 STPILPQAAG------PTSTPLLPQVPSIPPLVQPVANVPAVQQTL------IHSQPQPA 1625
++ P P +T L P + S Q + P + T+ SQ
Sbjct: 1727 TSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTR 1786
Query: 1626 LLPNQPHTHCPEVDSDTQPKAPG----IDDI-----------KTLEEKLRSLFSEHSSSG 1670
P T +VD T A G ++I K++E + +
Sbjct: 1787 CQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQV 1846
Query: 1671 AQHASVSLETSLVIES--------------------------------------TVTPGI 1692
Q + SLET L ++ + TPG
Sbjct: 1847 GQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGT 1906
Query: 1693 PTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTT---TSGVKPGT 1749
P+ T+T ST T P T+ P V +TP T+ T PGT
Sbjct: 1907 TWILTKPTTTATTTAST--GSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGT 1964
Query: 1750 APSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSP--E 1807
A + P L P T + P P SL + +L +T +P
Sbjct: 1965 ATALPALRSTATTPTAT----------SVTPIPSSSLGTTW-------TRLSQTTTPTAT 2007
Query: 1808 MITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAAD 1867
M T T + P + T +T AT++GA G +
Sbjct: 2008 MSTATPSSTPETAHTSTVLT-----------------ATATTTGA----TGSVATPSSTP 2046
Query: 1868 GAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAH- 1926
G K + S+S + L+ ST P G T+ S +P + H
Sbjct: 2047 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTV--TPSSIPGTTHT 2104
Query: 1927 -----KTTASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITDTKKEGPVASPPF 1981
TT + A P+ + T + +++ T + G PP
Sbjct: 2105 ATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPV 2164
Query: 1982 MDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPH 2034
+ A PA PS G + P S P SPH
Sbjct: 2165 L-TTTATTPAA-----TSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPH 2211
Score = 42.4 bits (98), Expect = 0.006
Identities = 88/366 (24%), Positives = 137/366 (37%), Gaps = 69/366 (18%)
Query: 596 SSASQTGIKQLPSASTG-----IPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVL 650
++ + T +PS+S G + +T +A++ST PE H + +
Sbjct: 3790 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET-AHTSTVLTTTATTTR 3848
Query: 651 SDGTVDS-----GQGSSVFTESRVSSQQTVSYGSQHEQAH------STGTVPGHIPSTVQ 699
+ G+V + G + + ++ TV+ S A ST T P STV
Sbjct: 3849 ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVT 3908
Query: 700 AQSQPHGVYPPS-------SVAQG---------QSQGQPSS--SSLTGVSSSQPIQHPQQ 741
S P + P+ +VA G Q+ G P S ++ T ++++ +P
Sbjct: 3909 PSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSS 3968
Query: 742 QQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSA---GKQLPVSQP- 797
G P T + + +TSS T + + P V P +A G+ L S P
Sbjct: 3969 TPGTTPIPPVLTTT--ATTPAATSSTVTPSSALGTTHTPPV-PNTTATTHGRSLSPSSPH 4025
Query: 798 ------VPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHV 851
G T+PS H+ P T Q+ S +S+PH
Sbjct: 4026 TVRTAWTSATSGTLGTTHITEPSTGTSHT---------PAATTGTTQH--STPALSSPHP 4074
Query: 852 STAQTGFSSLPITMAAGITQPLLTLASSATTA-AIPG---VSTVVPSQLPTLLQPVTQLP 907
S+ T P G T P T A+S TTA A P ST++PS PT T +
Sbjct: 4075 SSRTTESPPSP-----GTTTPGHTTATSRTTATATPSKTRTSTLLPSS-PTSAPITTVVT 4128
Query: 908 SQVHPQ 913
+ PQ
Sbjct: 4129 TGCEPQ 4134
Score = 40.8 bits (94), Expect = 0.016
Identities = 123/567 (21%), Positives = 184/567 (32%), Gaps = 124/567 (21%)
Query: 596 SSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLS-DGT 654
S+A+ + + ST + +TT+ + + P H + P+ + T
Sbjct: 2009 STATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTT---KVPTTTTTGFTAT 2065
Query: 655 VDSGQGSSVFTESRVSSQQT-VSYGSQHEQAHSTGTV-PGHIPSTVQAQSQPHGVYPPSS 712
S G+++ +S+ T + GS + GT + +T + PSS
Sbjct: 2066 PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSS 2125
Query: 713 VAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQ 772
Q +++ T ++++ +P G P T + + +TS+ T +
Sbjct: 2126 STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTT--ATTPAATSNTVTPSS 2183
Query: 773 PVSQPQAPQVLPQVSA---GKQLPVSQP----------VPTIQGEPQIPVATQPSVVPVH 819
+ P V P A G+ LP S P I G I T+PS V H
Sbjct: 2184 ALGTTHTPPV-PNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI---TEPSTVTSH 2239
Query: 820 SGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASS 879
+ A Q TP L S+PH S+ T P G T P T A+S
Sbjct: 2240 TLAATTGTTQH-STPAL----------SSPHPSSRTTESPPSP-----GTTTPGHTTATS 2283
Query: 880 ATTA-AIPG---VSTVVPSQLPTLLQPVTQLPSQVHPQLL-------------------- 915
TTA A P ST++PS PT T + PQ
Sbjct: 2284 RTTATATPSKTRTSTLLPSS-PTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFD 2342
Query: 916 --------------QP------AVQSMGIP-ANLGQAAEVPLSSGDVLYQ---------- 944
QP A G+P LGQ E L G V
Sbjct: 2343 TYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMC 2402
Query: 945 ------------GFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVL------- 985
G P P S PSS + I + + + TE
Sbjct: 2403 FNYEIRVFCCNYGHCPSTPAT---SSTAMPSSTPGTTWILTELTTTATTTESTGSTATPS 2459
Query: 986 ATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGG-----SLAQAPTTSSQQAVLESTQ 1040
+TPG + +P + + VP G G + A PT +S +A S+
Sbjct: 2460 STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSP 2519
Query: 1041 GVSQVAPAEPVAVAQTQATQPTTLASS 1067
G + PA AT T + SS
Sbjct: 2520 GTATALPALRSTATTPTATSFTAIPSS 2546
Score = 40.0 bits (92), Expect = 0.027
Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 16/184 (8%)
Query: 1337 PPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPT-EEGIAGVA-TST-GVV 1393
PP TT A P +S P ++ + S VPT EG+ TST G
Sbjct: 1614 PPTTELETATTTTTQALFSTPQPTSSPG-LTRAPPASTTAVPTLSEGLTSPRYTSTLGTA 1672
Query: 1394 TSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTV 1453
T+GG P P + V++ T+P ++ T+ SL + ++ T +
Sbjct: 1673 TTGG-PTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTM------ 1725
Query: 1454 SATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSST 1513
ATS + TA+ K P S + T+ + L++ TS P T + +S +++T
Sbjct: 1726 -ATSRARPTGTASTASKEPLTTSL----APTLTSELSTSQAETSTPRTETTMSPLTNTTT 1780
Query: 1514 STPT 1517
S T
Sbjct: 1781 SQGT 1784
Score = 38.1 bits (87), Expect = 0.10
Identities = 89/374 (23%), Positives = 136/374 (36%), Gaps = 85/374 (22%)
Query: 596 SSASQTGIKQLPSASTG-----IPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVL 650
++ + T +PS+S G + +T +A++ST PE + +VL
Sbjct: 2533 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH---------TSTVL 2583
Query: 651 SDGTVDSGQGSSVFTES---------RVSSQQTVSYGSQHEQAH----------STGTVP 691
+ +G SV T S +V + T + + + ST T P
Sbjct: 2584 TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTP 2643
Query: 692 GHIPSTVQAQSQPHGVYPPS-------SVAQG---------QSQGQPSS--SSLTGVSSS 733
STV S P + P+ +VA G Q+ G P S ++ T ++++
Sbjct: 2644 TTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITAT 2703
Query: 734 QPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSA---GK 790
+P G P T + + +TSS T + + P V P +A G+
Sbjct: 2704 GSTTNPSSTPGTTPIPPVLTTT--ATTPAATSSTVTPSSALGTTHTPPV-PNTTATTHGR 2760
Query: 791 QLPVSQP-------VPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQ 843
L S P G T+PS H+ P T Q+ S
Sbjct: 2761 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHT---------PAATTGTTQH--ST 2809
Query: 844 IPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTA-AIPG---VSTVVPSQLPTL 899
+S+PH S+ T P G T P T A+S TTA A P ST++PS PT
Sbjct: 2810 PALSSPHPSSRTTESPPSP-----GTTTPGHTRATSRTTATATPSKTRTSTLLPSS-PTS 2863
Query: 900 LQPVTQLPSQVHPQ 913
T + PQ
Sbjct: 2864 APITTVVTMGCEPQ 2877
Score = 35.4 bits (80), Expect = 0.67
Identities = 49/183 (26%), Positives = 73/183 (39%), Gaps = 17/183 (9%)
Query: 748 TAPPQQTVQYSLSQTSTSSEATTAQPVSQP---QAP----QVLPQVSAGKQLP--VSQPV 798
T PP T + + T+T + +T QP S P +AP +P +S G P S
Sbjct: 1611 TTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLG 1670
Query: 799 PTIQGEPQIPV-ATQPSVVPVHSGAHFLPVGQPLP--TPLLPQYPVSQIPISTPHVSTAQ 855
G P P +T+P+V V + LP LP T L + SQ P P +T
Sbjct: 1671 TATTGGPTTPAGSTEPTVPGVATST--LPTRSALPGTTGSLGTWRPSQPPTLAP--TTMA 1726
Query: 856 TGFSSLPITMAAGITQPLLT-LASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQL 914
T + T + +PL T LA + T+ + + T + P+T +
Sbjct: 1727 TSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTR 1786
Query: 915 LQP 917
QP
Sbjct: 1787 CQP 1789
Score = 33.9 bits (76), Expect = 2.0
Identities = 50/208 (24%), Positives = 70/208 (33%), Gaps = 34/208 (16%)
Query: 2 SGGAAEKQSSTPGSLFL--SPPAPAP---KNGSSSDSSVGEKLGAAAADAVTGRTEEYRR 56
S G+ SSTPG+ ++ P A GS++ +S + + T T
Sbjct: 3708 STGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTS 3767
Query: 57 RRHTMDKDSRGAAA------TTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAA 110
+ T A A T TT F T L + P ++ A
Sbjct: 3768 SKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLS--QTTTPTATMSTA 3825
Query: 111 VPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPST-----VPSSTSKDRP 165
P S P H +T TAT+ A G A P T VP++T+
Sbjct: 3826 TPSSTPETAHTSTVLTTTATT--------TRATGSVATPSSTPGTAHTTKVPTTTTTGFT 3877
Query: 166 VSQPSLVGSKEEPP--------PARSGS 185
V+ S G+ PP P SGS
Sbjct: 3878 VTPSSSPGTARTPPVWISTTTTPTTSGS 3905
Score = 33.5 bits (75), Expect = 2.6
Identities = 46/194 (23%), Positives = 66/194 (34%), Gaps = 26/194 (13%)
Query: 2 SGGAAEKQSSTPGSLFL--SPPAPAP---KNGSSSDSSVGEKLGAAAADAVTGRTEEYRR 56
S G+ SSTPG+ ++ P A GS++ +S + + T T
Sbjct: 4436 STGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTS 4495
Query: 57 RRHTMDKDSRGAAA------TTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPSIPAA 110
+ T A A T TT F T L + P ++ A
Sbjct: 4496 SKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLS--QTTTPTATMSTA 4553
Query: 111 VPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPST-----VPSSTSKDRP 165
P S P H +TATAT+ A G A P T VP++T+
Sbjct: 4554 TPSSTPETVHTSTVLTATATT--------TGATGSVATPSSTPGTAHTTKVPTTTTTGFT 4605
Query: 166 VSQPSLVGSKEEPP 179
+ S G+ PP
Sbjct: 4606 ATPSSSPGTALTPP 4619
Score = 33.1 bits (74), Expect = 3.3
Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 8/116 (6%)
Query: 1495 TTSFPSTASQLSIQLSSSTSTPTLAETVV-VSAHSLDKTSHSSTTG---LAFSLSAPSSS 1550
TT P+T ++ +++T+T L T S+ L + +STT L+ L++P +
Sbjct: 1611 TTPPPTT----ELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYT 1666
Query: 1551 SSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQP 1606
S+ G + + P G +P V ST A T+ L PS PP + P
Sbjct: 1667 STLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAP 1722
Score = 32.0 bits (71), Expect = 7.5
Identities = 47/186 (25%), Positives = 74/186 (39%), Gaps = 28/186 (15%)
Query: 607 PSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTE 666
P +T + TA+TT+ TQ P+ L + P S + T+ G S +T
Sbjct: 1613 PPPTTELETATTTT----TQALFSTPQPTSSPGLT-RAPPASTTAVPTLSEGLTSPRYT- 1666
Query: 667 SRVSSQQTVSYGSQHEQAHSTG-TVPGHIPSTVQAQSQPHGV----------YPPS--SV 713
S+ T + G A ST TVPG ST+ +S G PP+
Sbjct: 1667 ---STLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPT 1723
Query: 714 AQGQSQGQPSSSSLTG-----VSSSQPIQHPQQQQGIQQTAPPQ-QTVQYSLSQTSTSSE 767
S+ +P+ ++ T +S P + +T+ P+ +T L+ T+TS
Sbjct: 1724 TMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQG 1783
Query: 768 ATTAQP 773
T QP
Sbjct: 1784 TTRCQP 1789
Score = 31.6 bits (70), Expect = 9.7
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 19/92 (20%)
Query: 1393 VTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVT 1452
V G P P S P LS+ +T P++ PT T+ ++ + PS+
Sbjct: 1433 VPCGPSPAPGTSPQPSLSA--------------STEPAVPTPTQTTATEKTTLWVTPSIR 1478
Query: 1453 VSATSASAGGSTATPGPKPPAVVSQQAAGSTT 1484
+A S GS++ P V+ A G+TT
Sbjct: 1479 STAALTSQTGSSS-----GPVTVTPSAPGTTT 1505
Score = 31.6 bits (70), Expect = 9.7
Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 13/82 (15%)
Query: 103 PQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPST-----VP 157
P ++ A P S P H +TATAT+ A G A P T VP
Sbjct: 2004 PTATMSTATPSSTPETAHTSTVLTATATT--------TGATGSVATPSSTPGTAHTTKVP 2055
Query: 158 SSTSKDRPVSQPSLVGSKEEPP 179
++T+ + S G+ PP
Sbjct: 2056 TTTTTGFTATPSSSPGTALTPP 2077
>gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens]
Length = 553
Score = 112 bits (281), Expect = 3e-24
Identities = 99/370 (26%), Positives = 176/370 (47%), Gaps = 24/370 (6%)
Query: 108 PAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVS 167
PA P S E ++ AT +A +P + ++V P P T ++D S
Sbjct: 168 PAVPPVS---EDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVT----PTRDVATS 220
Query: 168 QPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEI 227
S + PP A + + + K+ ++ + ++ +E+L + ++ +F+ +I
Sbjct: 221 PISPTENNTTPPDALTRN---TEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFE-KI 276
Query: 228 GRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSW 287
G+G+ TVY +D T EVA ++ ++ K E E +++ ++PNIV + DS+
Sbjct: 277 GQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKEL--IINEILVMRENKNPNIVNYLDSY 334
Query: 288 ESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIH 347
+ G + V V E + G+L + M + + CR+ L+ L+FLH+ +IH
Sbjct: 335 ---LVGDELWV-VMEYLAGGSLTDVVTE-TCMDEGQIAAVCRECLQALEFLHSNQ--VIH 387
Query: 348 RDLKCDNIFITGPTGSVKIGDLGLAT--LKRASFAKSVIGTPEFMAPEMYEEK-YDESVD 404
RD+K DNI + G GSVK+ D G S +++GTP +MAPE+ K Y VD
Sbjct: 388 RDIKSDNILL-GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVD 446
Query: 405 VYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNK 464
+++ G+ +EM E PY +Y T+G + ++ + C+ +
Sbjct: 447 IWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDV 506
Query: 465 DERYSIKDLL 474
++R S K+LL
Sbjct: 507 EKRGSAKELL 516
>gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo
sapiens]
Length = 1328
Score = 112 bits (279), Expect = 6e-24
Identities = 76/269 (28%), Positives = 138/269 (51%), Gaps = 25/269 (9%)
Query: 227 IGRGSFKTVYKGLDTE---TTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
+G+G++ TVY GL ++ V+ + ++ + E ++ +EE ++LK L+H NIV +
Sbjct: 1067 LGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAY 1126
Query: 284 YDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTP 343
T + + + E + G++ + + RF + V + +QIL+G+ +LH
Sbjct: 1127 L----GTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENC- 1181
Query: 344 PIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFA----------KSVIGTPEFMAPE 393
++HRD+K +N+ + PTG +K+ D G A +R ++A KS+ GTP +MAPE
Sbjct: 1182 -VVHRDIKGNNVMLM-PTGIIKLIDFGCA--RRLAWAGLNGTHSDMLKSMHGTPYWMAPE 1237
Query: 394 MYEEK-YDESVDVYAFGMCMLEMATSEYPYSECQN-AAQIYRRVTSGVKPASFDKVAIPE 451
+ E Y D+++ G + EMAT + P + AA Y G+ P D +
Sbjct: 1238 VINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFS-EN 1296
Query: 452 VKEIIEGCIRQNKDERYSIKDLLNHAFFQ 480
+ + C+ +++ ER S LL H+F +
Sbjct: 1297 AADFVRMCLTRDQHERPSALQLLKHSFLE 1325
>gi|63998898 Yeast Sps1/Ste20-related kinase 4 isoform 2 [Homo
sapiens]
Length = 510
Score = 112 bits (279), Expect = 6e-24
Identities = 76/269 (28%), Positives = 138/269 (51%), Gaps = 25/269 (9%)
Query: 227 IGRGSFKTVYKGLDTE---TTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
+G+G++ TVY GL ++ V+ + ++ + E ++ +EE ++LK L+H NIV +
Sbjct: 249 LGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAY 308
Query: 284 YDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTP 343
T + + + E + G++ + + RF + V + +QIL+G+ +LH
Sbjct: 309 L----GTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENC- 363
Query: 344 PIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFA----------KSVIGTPEFMAPE 393
++HRD+K +N+ + PTG +K+ D G A +R ++A KS+ GTP +MAPE
Sbjct: 364 -VVHRDIKGNNVMLM-PTGIIKLIDFGCA--RRLAWAGLNGTHSDMLKSMHGTPYWMAPE 419
Query: 394 MYEEK-YDESVDVYAFGMCMLEMATSEYPYSECQN-AAQIYRRVTSGVKPASFDKVAIPE 451
+ E Y D+++ G + EMAT + P + AA Y G+ P D +
Sbjct: 420 VINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFS-EN 478
Query: 452 VKEIIEGCIRQNKDERYSIKDLLNHAFFQ 480
+ + C+ +++ ER S LL H+F +
Sbjct: 479 AADFVRMCLTRDQHERPSALQLLKHSFLE 507
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 109 bits (273), Expect = 3e-23
Identities = 130/591 (21%), Positives = 243/591 (41%), Gaps = 58/591 (9%)
Query: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP-NIVRFYD 285
+G G++ VYKG +T ++A ++ D +T E + K+E MLK H NI +Y
Sbjct: 31 VGNGTYGQVYKGRHVKTG-QLAAIKVMD--VTGDEEEEIKQEINMLKKYSHHRNIATYYG 87
Query: 286 SW--ESTVKGKKCIVLVTELMTSGTLKTYLKRFK--VMKIKVLRSWCRQILKGLQFLHTR 341
++ ++ + LV E +G++ +K K +K + + CR+IL+GL LH
Sbjct: 88 AFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH 147
Query: 342 TPPIIHRDLKCDNIFITGPTGSVKIGDLGL-ATLKRASFAKSV-IGTPEFMAPEMY---- 395
+IHRD+K N+ +T VK+ D G+ A L R ++ IGTP +MAPE+
Sbjct: 148 K--VIHRDIKGQNVLLT-ENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDE 204
Query: 396 --EEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVK 453
+ YD D+++ G+ +EMA P + ++ + P K + +
Sbjct: 205 NPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFL-IPRNPAPRLKSKKWSKKFQ 263
Query: 454 EIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLK 513
IE C+ +N +R + + L+ H F +++ R ++ I+L I+ KK +
Sbjct: 264 SFIESCLVKNHSQRPATEQLMKHPFIRDQPNER----------QVRIQLKDHIDRTKKKR 313
Query: 514 GKYKDNEAIEFSFDLERDVPEDVAQEM----VESGYVCEGDHKTMAKAIKDRVSLIKRKR 569
G+ KD E+S E + D + + D + A K+R ++R++
Sbjct: 314 GE-KDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQ 372
Query: 570 EQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTS--ASVSTQV 627
++Q RE +E K+Q + ++++E+ + +++ + Q+
Sbjct: 373 LEQQ-QRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQM 431
Query: 628 EPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHST 687
EE + +Y++ + + Q + + + VS Q ++
Sbjct: 432 RREEERRRAEHEQEYKRKQLE-------EQRQAERLQRQLKQERDYLVSLQHQRQEQRPV 484
Query: 688 GTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQ 747
P G+ P A + + S + S P + I
Sbjct: 485 EKKP--------LYHYKEGMSPSEKPAWAKEVEERSRLN----RQSSPAMPHKVANRISD 532
Query: 748 TAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPV 798
P ++ +S+S + +PV PQ P ++ S G L SQ V
Sbjct: 533 PNLPPRSESFSISGVQPARTPPMLRPV-DPQIPHLVAVKSQGPALTASQSV 582
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 109 bits (273), Expect = 3e-23
Identities = 130/591 (21%), Positives = 243/591 (41%), Gaps = 58/591 (9%)
Query: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHP-NIVRFYD 285
+G G++ VYKG +T ++A ++ D +T E + K+E MLK H NI +Y
Sbjct: 31 VGNGTYGQVYKGRHVKTG-QLAAIKVMD--VTGDEEEEIKQEINMLKKYSHHRNIATYYG 87
Query: 286 SW--ESTVKGKKCIVLVTELMTSGTLKTYLKRFK--VMKIKVLRSWCRQILKGLQFLHTR 341
++ ++ + LV E +G++ +K K +K + + CR+IL+GL LH
Sbjct: 88 AFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH 147
Query: 342 TPPIIHRDLKCDNIFITGPTGSVKIGDLGL-ATLKRASFAKSV-IGTPEFMAPEMY---- 395
+IHRD+K N+ +T VK+ D G+ A L R ++ IGTP +MAPE+
Sbjct: 148 K--VIHRDIKGQNVLLT-ENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDE 204
Query: 396 --EEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVK 453
+ YD D+++ G+ +EMA P + ++ + P K + +
Sbjct: 205 NPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFL-IPRNPAPRLKSKKWSKKFQ 263
Query: 454 EIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLK 513
IE C+ +N +R + + L+ H F +++ R ++ I+L I+ KK +
Sbjct: 264 SFIESCLVKNHSQRPATEQLMKHPFIRDQPNER----------QVRIQLKDHIDRTKKKR 313
Query: 514 GKYKDNEAIEFSFDLERDVPEDVAQEM----VESGYVCEGDHKTMAKAIKDRVSLIKRKR 569
G+ KD E+S E + D + + D + A K+R ++R++
Sbjct: 314 GE-KDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQ 372
Query: 570 EQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTS--ASVSTQV 627
++Q RE +E K+Q + ++++E+ + +++ + Q+
Sbjct: 373 LEQQ-QRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQM 431
Query: 628 EPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHST 687
EE + +Y++ + + Q + + + VS Q ++
Sbjct: 432 RREEERRRAEHEQEYKRKQLE-------EQRQAERLQRQLKQERDYLVSLQHQRQEQRPV 484
Query: 688 GTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQ 747
P G+ P A + + S + S P + I
Sbjct: 485 EKKP--------LYHYKEGMSPSEKPAWAKEVEERSRLN----RQSSPAMPHKVANRISD 532
Query: 748 TAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPV 798
P ++ +S+S + +PV PQ P ++ S G L SQ V
Sbjct: 533 PNLPPRSESFSISGVQPARTPPMLRPV-DPQIPHLVAVKSQGPALTASQSV 582
>gi|217330634 serine/threonine kinase 36 [Homo sapiens]
Length = 1315
Score = 109 bits (273), Expect = 3e-23
Identities = 92/334 (27%), Positives = 160/334 (47%), Gaps = 19/334 (5%)
Query: 227 IGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDS 286
IG GSF VYKG + VA + ++ E + + E E+++GL+HPNIV DS
Sbjct: 10 IGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDS 69
Query: 287 WESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPII 346
+E+ K +V+VT+ G L L+ + +++ Q++ L +LH+ I+
Sbjct: 70 FET----DKEVVVVTD-YAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR--IL 122
Query: 347 HRDLKCDNIFITGPTGSVKIGDLGLATLKRAS--FAKSVIGTPEFMAPEMYEEK-YDESV 403
HRD+K NI + G +K+ D G A + S+ GTP +M+PE+ EE+ YD +
Sbjct: 123 HRDMKPQNILL-AKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTA 181
Query: 404 DVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVK-PASFDKVAIPEVKEIIEGCIRQ 462
D+++ G + E+A P+ A I++ V+ +K P + P K ++G + +
Sbjct: 182 DLWSVGCILYELAVGTPPF----YATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTK 237
Query: 463 NKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKY---KDN 519
+ +R S DLL H F + E A D G +L ++ +K + K N
Sbjct: 238 DPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGN 297
Query: 520 EAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKT 553
++ + +R E + ++ +G E + KT
Sbjct: 298 QSRILTQAYKRMAEEAMQKKHQNTGPALEQEDKT 331
>gi|33188459 B-Raf [Homo sapiens]
Length = 766
Score = 109 bits (272), Expect = 4e-23
Identities = 112/403 (27%), Positives = 178/403 (44%), Gaps = 64/403 (15%)
Query: 100 LSLPQPSIPAAVPQSAPP--EPHREETVTATATSQVAQQPPAAAAPG------------- 144
L+ P PS +PQ P E HR +Q Q+ +++AP
Sbjct: 331 LTSPSPSKSIPIPQPFRPADEDHR---------NQFGQRDRSSSAPNVHINTIEPVNIDD 381
Query: 145 ---EQAVAGPAPSTVPSSTSKDR--PVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQ 199
+Q G ST S + P S ++ ++ P P R S+++ ++
Sbjct: 382 LIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTL 441
Query: 200 QQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTK 259
+ D + G G+ IG GSF TVYKG + +VA L T
Sbjct: 442 GRRDSSDDWEIPDGQITVGQ------RIGSGSFGTVYKG---KWHGDVAVKMLNVTAPTP 492
Query: 260 SERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLK----R 315
+ Q FK E +L+ +H NI+ F K + +VT+ +L +L +
Sbjct: 493 QQLQAFKNEVGVLRKTRHVNILLFMG-----YSTKPQLAIVTQWCEGSSLYHHLHIIETK 547
Query: 316 FKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 375
F+++K+ + RQ +G+ +LH ++ IIHRDLK +NIF+ +VKIGD GLAT+K
Sbjct: 548 FEMIKLIDI---ARQTAQGMDYLHAKS--IIHRDLKSNNIFLHEDL-TVKIGDFGLATVK 601
Query: 376 R----ASFAKSVIGTPEFMAPEMY----EEKYDESVDVYAFGMCMLEMATSEYPYSECQN 427
+ + + G+ +MAPE+ + Y DVYAFG+ + E+ T + PYS N
Sbjct: 602 SRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 661
Query: 428 AAQIYRRVTSGVKPASFDKV---AIPEVKEIIEGCIRQNKDER 467
QI V G KV +K ++ C+++ +DER
Sbjct: 662 RDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDER 704
Score = 33.5 bits (75), Expect = 2.6
Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 751 PQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQP 797
PQ+ + SL++T+ +S ++ + P S PQ+L S K +P+ QP
Sbjct: 301 PQE--EASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQP 345
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 108 bits (271), Expect = 5e-23
Identities = 129/566 (22%), Positives = 199/566 (35%), Gaps = 54/566 (9%)
Query: 1316 TEGPNTAP--------PNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDIS 1367
T+ P T P P + TG P P ++ PT P T+ P +
Sbjct: 1916 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTT 1973
Query: 1368 TSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITI--------- 1418
T+V + T+ T+T VT P P +++P + + ++ T+
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2031
Query: 1419 --PAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGP-KPPAVV 1475
P I+TT+ PT T ++T + + TV+ T G T T P V
Sbjct: 2032 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2091
Query: 1476 SQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHS 1535
+ + T T T ++TTT+ T + Q + T+TP T V + T
Sbjct: 2092 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTP 2149
Query: 1536 STTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLP 1595
+TT + + + + + G +Q P+ + + TP PT+TP+
Sbjct: 2150 TTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202
Query: 1596 QVPSIP---------PLVQPVANVPAVQQTLIHSQPQ-PALLPNQPHTHCPEVDSDTQPK 1645
P P P+ V T + Q P P T + T +
Sbjct: 2203 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2262
Query: 1646 APGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTS 1705
P I T ++ + +G Q + T + +TVTP T
Sbjct: 2263 TPTTTPITT----TTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTPI 2315
Query: 1706 TTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPV-LPV 1764
TT+T + PT P GT TP+ T V TP T T P T P T P P
Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2374
Query: 1765 GTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPT 1824
GT+ P T + P P+ T +Q P T++P T T P + T
Sbjct: 2375 GTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTP-TPTGTQTPTTTPITT 2432
Query: 1825 AITEAGTQPQKGVSQVKEGPVLATSS 1850
T T G P+ T++
Sbjct: 2433 TTTVTPTPTPTGTQTPTTTPITTTTT 2458
Score = 108 bits (270), Expect = 6e-23
Identities = 126/553 (22%), Positives = 195/553 (35%), Gaps = 46/553 (8%)
Query: 1321 TAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTE 1380
T P + TG P P ++ PT P T+ P +T+V + T+
Sbjct: 1906 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQ 1963
Query: 1381 EGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITI-----------PAVVSISTTSP 1429
T+T VT P P +++P + + ++ T+ P I+TT+
Sbjct: 1964 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2021
Query: 1430 SLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGP-KPPAVVSQQAAGSTTVGAT 1488
PT T ++T + + TV+ T G T T P V+ + T T
Sbjct: 2022 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2081
Query: 1489 LTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPS 1548
T ++TTT+ T + Q + T+TP T V + T +TT + + +
Sbjct: 2082 TTPITTTTTVTPTPTPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2139
Query: 1549 SSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIP------- 1601
+ + G +Q P+ + + TP PT+TP+ P
Sbjct: 2140 TPTPTG-------TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2192
Query: 1602 --PLVQPVANVPAVQQTLIHSQPQ-PALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEK 1658
P P+ V T + Q P P T + T + P I T
Sbjct: 2193 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---- 2248
Query: 1659 LRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPL 1718
++ + +G Q + T + +TVTP T TT+T + PT P
Sbjct: 2249 TTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2305
Query: 1719 GTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQ 1777
GT TP+ T V TP T T P T P T P P GT+ P T +
Sbjct: 2306 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2364
Query: 1778 LPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGV 1837
P P+ T +Q P T++P T T P + T T T G
Sbjct: 2365 TTVTPTPTPTGTQTP-TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGT 2422
Query: 1838 SQVKEGPVLATSS 1850
P+ T++
Sbjct: 2423 QTPTTTPITTTTT 2435
Score = 108 bits (270), Expect = 6e-23
Identities = 165/772 (21%), Positives = 264/772 (34%), Gaps = 98/772 (12%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
PI ++ PT + T V+P P ++ + IT T + +
Sbjct: 3579 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPT 3637
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP--------PNFSHTGPTFPVVPPFLS 1341
P + + + ++ + T+ P T P P + TG P P +
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ PT P T+ P +T+V + T+ T+T VT P P
Sbjct: 3698 TTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTP 3753
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS-- 1459
+++P + + ++ T V+ + T Q PT+T + ++T + P+ T + T
Sbjct: 3754 TGTQTPTTTPITTTTT----VTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 3807
Query: 1460 ---AGGSTATPGPKPPAVVSQQAAGSTTVGA-------------TLTSVSTTTSFPSTAS 1503
+T TP P P + TT T T ++TTT+ T +
Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3867
Query: 1504 QLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQ 1563
Q + T+TP T V + T +TT + + + + + G +Q
Sbjct: 3868 PTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQ 3918
Query: 1564 PGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVANVPAVQ 1614
P+ + + TP PT+TP+ P P P+ V
Sbjct: 3919 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3978
Query: 1615 QTLIHSQPQ-PALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQH 1673
T + Q P P T + T + P I T ++ + +G Q
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTPTGTQT 4034
Query: 1674 ASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQ 1733
+ T + +TVTP T TT+T + PT P GT TP+ T
Sbjct: 4035 PTT---TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4091
Query: 1734 VSTPVSTTTSGVKPGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQP 1792
V TP T T P T P T P P GT+ P T + P P+ T +Q P
Sbjct: 4092 V-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4150
Query: 1793 LEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTA---ITEAGTQPQKGVSQVKEGPVLATS 1849
T TVT P PT T P + + GP TS
Sbjct: 4151 --------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTS 4202
Query: 1850 SGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPEST------ 1903
+ A + ++ + Q S +S S+ + ++S++P ST
Sbjct: 4203 T-APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTT 4261
Query: 1904 -----LVKPEPNGITIP----------GISSDVPESAHKTTASEAKSDTGQP 1940
+ P P+ T P G SS S +TT + A + T P
Sbjct: 4262 TSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313
Score = 107 bits (266), Expect = 2e-22
Identities = 143/577 (24%), Positives = 215/577 (37%), Gaps = 62/577 (10%)
Query: 1316 TEGPNTAPPNFSHTGPTF-PVVPPFLSSIA------GVPTTAAATAPVPATSSPPNDIST 1368
T T PP + + PT P+ PP ++ PTT T P T SPP
Sbjct: 1488 TTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547
Query: 1369 SVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSI----TIPAVVSI 1424
+ S T+P + T+T P PP + +P ++ ++ T P+ +
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607
Query: 1425 STTSP---SLQVPTSTSEIV--VSSTALYPSVTVSA--TSASAGGSTATPGPKPPAVVSQ 1477
+TT+P + P +T+ I S+T L P+ T S T+ + T TP P S
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667
Query: 1478 QAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSST 1537
+TT T T S T+ PS + ++ S T+TP+ T + S S T
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTT-TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT 1726
Query: 1538 TGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQV 1597
T ++ PS +++P ++ + P P S + +TP+ P PT +P
Sbjct: 1727 T-----MTTPSPTTTPSPPTTTMTTLP----PTTTSSPLTTTPLPPSITPPTFSPFSTTT 1777
Query: 1598 PSIP--PLV---------QPVANVPAVQQTLIHSQPQPALLPNQP--HTHCPEVDSDTQP 1644
P+ P PL +P + P LI P N T P+V
Sbjct: 1778 PTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLG 1837
Query: 1645 KAPGID-----DIKTLEEK----LRSLFSEHSSSGAQHAS-VSLETSLVIESTVTPGIPT 1694
+ D K ++K + F + Q V+ T++ +T P PT
Sbjct: 1838 QTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPT 1897
Query: 1695 TAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKP 1754
T TT+T + PT P GT TP+ T V TP T T P T P
Sbjct: 1898 TT-------PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITT 1949
Query: 1755 PLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTS 1813
T P P GT+ P T + P P+ T +Q P T++P T T
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTP-TPTG 2007
Query: 1814 AVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
P + T T T G P+ T++
Sbjct: 2008 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2044
Score = 106 bits (265), Expect = 2e-22
Identities = 124/543 (22%), Positives = 192/543 (35%), Gaps = 46/543 (8%)
Query: 1331 PTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATST 1390
PT P P ++ PT P T+ P +T+V + T+ T+T
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTT 1950
Query: 1391 GVVTSGGLPIPPVSESPVLSSVVSSITI-----------PAVVSISTTSPSLQVPTSTSE 1439
VT P P +++P + + ++ T+ P I+TT+ PT T
Sbjct: 1951 TTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008
Query: 1440 IVVSSTALYPSVTVSATSASAGGSTATPGP-KPPAVVSQQAAGSTTVGATLTSVSTTTSF 1498
++T + + TV+ T G T T P V+ + T T T ++TTT+
Sbjct: 2009 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2068
Query: 1499 PSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVS 1558
T + Q + T+TP T V + T +TT + + + + + G
Sbjct: 2069 TPTPTPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---- 2122
Query: 1559 SYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVAN 1609
+Q P+ + + TP PT+TP+ P P P+
Sbjct: 2123 ---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2179
Query: 1610 VPAVQQTLIHSQPQ-PALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSS 1668
V T + Q P P T + T + P I T ++ +
Sbjct: 2180 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTP 2235
Query: 1669 SGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPV 1728
+G Q + T + +TVTP T TT+T + PT P GT TP+
Sbjct: 2236 TGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292
Query: 1729 VTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLT 1787
T V TP T T P T P T P P GT+ P T + P P+ T
Sbjct: 2293 TTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2351
Query: 1788 QSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLA 1847
+Q P T++P T T P + T T T G P+
Sbjct: 2352 GTQTP-TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409
Query: 1848 TSS 1850
T++
Sbjct: 2410 TTT 2412
Score = 105 bits (262), Expect = 5e-22
Identities = 140/645 (21%), Positives = 226/645 (35%), Gaps = 64/645 (9%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
PI ++ PT + T V+P P ++ + IT T + +
Sbjct: 2084 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPT 2142
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP--------PNFSHTGPTFPVVPPFLS 1341
P + + + ++ + T+ P T P P + TG P P +
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ PT P T+ P +T+V + T+ T+T VT P P
Sbjct: 2203 TTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTP 2258
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS-- 1459
+++P + + ++ T V+ + T Q PT+T + ++T + P+ T + T
Sbjct: 2259 TGTQTPTTTPITTTTT----VTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 2312
Query: 1460 ---AGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTP 1516
+T TP P P + T T T ++TTT+ T + Q + T+TP
Sbjct: 2313 TPITTTTTVTPTPTP----------TGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTP 2360
Query: 1517 TLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVI 1576
T V + T +TT + + + + + G +Q P+ + +
Sbjct: 2361 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTTV 2413
Query: 1577 ASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVANVPAVQQTLIHSQPQ-PAL 1626
TP PT+TP+ P P P+ V T + Q P
Sbjct: 2414 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473
Query: 1627 LPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIES 1686
P T + T + P I T ++ + +G Q + T + +
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTPTGTQTPTT---TPITTTT 2526
Query: 1687 TVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVK 1746
TVTP T TT+T + PT P GT TP+ T V TP T T
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 2585
Query: 1747 PGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLS 1805
P T P T P P GT+ P T + P P+ T +Q P T++
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVT 2644
Query: 1806 PEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
P T T P + T T T G P+ T++
Sbjct: 2645 PTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688
Score = 105 bits (262), Expect = 5e-22
Identities = 140/645 (21%), Positives = 226/645 (35%), Gaps = 64/645 (9%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
PI ++ PT + T V+P P ++ + IT T + +
Sbjct: 2383 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPT 2441
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP--------PNFSHTGPTFPVVPPFLS 1341
P + + + ++ + T+ P T P P + TG P P +
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ PT P T+ P +T+V + T+ T+T VT P P
Sbjct: 2502 TTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTP 2557
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS-- 1459
+++P + + ++ T V+ + T Q PT+T + ++T + P+ T + T
Sbjct: 2558 TGTQTPTTTPITTTTT----VTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 2611
Query: 1460 ---AGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTP 1516
+T TP P P + T T T ++TTT+ T + Q + T+TP
Sbjct: 2612 TPITTTTTVTPTPTP----------TGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTP 2659
Query: 1517 TLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVI 1576
T V + T +TT + + + + + G +Q P+ + +
Sbjct: 2660 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTTV 2712
Query: 1577 ASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVANVPAVQQTLIHSQPQ-PAL 1626
TP PT+TP+ P P P+ V T + Q P
Sbjct: 2713 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772
Query: 1627 LPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIES 1686
P T + T + P I T ++ + +G Q + T + +
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTPTGTQTPTT---TPITTTT 2825
Query: 1687 TVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVK 1746
TVTP T TT+T + PT P GT TP+ T V TP T T
Sbjct: 2826 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 2884
Query: 1747 PGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLS 1805
P T P T P P GT+ P T + P P+ T +Q P T++
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVT 2943
Query: 1806 PEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
P T T P + T T T G P+ T++
Sbjct: 2944 PTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2987
Score = 105 bits (262), Expect = 5e-22
Identities = 140/645 (21%), Positives = 226/645 (35%), Gaps = 64/645 (9%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
PI ++ PT + T V+P P ++ + IT T + +
Sbjct: 2682 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPT 2740
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP--------PNFSHTGPTFPVVPPFLS 1341
P + + + ++ + T+ P T P P + TG P P +
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ PT P T+ P +T+V + T+ T+T VT P P
Sbjct: 2801 TTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTP 2856
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS-- 1459
+++P + + ++ T V+ + T Q PT+T + ++T + P+ T + T
Sbjct: 2857 TGTQTPTTTPITTTTT----VTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 2910
Query: 1460 ---AGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTP 1516
+T TP P P + T T T ++TTT+ T + Q + T+TP
Sbjct: 2911 TPITTTTTVTPTPTP----------TGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTP 2958
Query: 1517 TLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVI 1576
T V + T +TT + + + + + G +Q P+ + +
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTTV 3011
Query: 1577 ASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVANVPAVQQTLIHSQPQ-PAL 1626
TP PT+TP+ P P P+ V T + Q P
Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071
Query: 1627 LPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIES 1686
P T + T + P I T ++ + +G Q + T + +
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTPTGTQTPTT---TPITTTT 3124
Query: 1687 TVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVK 1746
TVTP T TT+T + PT P GT TP+ T V TP T T
Sbjct: 3125 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3183
Query: 1747 PGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLS 1805
P T P T P P GT+ P T + P P+ T +Q P T++
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVT 3242
Query: 1806 PEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
P T T P + T T T G P+ T++
Sbjct: 3243 PTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3286
Score = 105 bits (262), Expect = 5e-22
Identities = 140/645 (21%), Positives = 226/645 (35%), Gaps = 64/645 (9%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
PI ++ PT + T V+P P ++ + IT T + +
Sbjct: 2981 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPT 3039
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP--------PNFSHTGPTFPVVPPFLS 1341
P + + + ++ + T+ P T P P + TG P P +
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ PT P T+ P +T+V + T+ T+T VT P P
Sbjct: 3100 TTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTP 3155
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS-- 1459
+++P + + ++ T V+ + T Q PT+T + ++T + P+ T + T
Sbjct: 3156 TGTQTPTTTPITTTTT----VTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 3209
Query: 1460 ---AGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTP 1516
+T TP P P + T T T ++TTT+ T + Q + T+TP
Sbjct: 3210 TPITTTTTVTPTPTP----------TGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTP 3257
Query: 1517 TLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVI 1576
T V + T +TT + + + + + G +Q P+ + +
Sbjct: 3258 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTTV 3310
Query: 1577 ASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVANVPAVQQTLIHSQPQ-PAL 1626
TP PT+TP+ P P P+ V T + Q P
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370
Query: 1627 LPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIES 1686
P T + T + P I T ++ + +G Q + T + +
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTPTGTQTPTT---TPITTTT 3423
Query: 1687 TVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVK 1746
TVTP T TT+T + PT P GT TP+ T V TP T T
Sbjct: 3424 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3482
Query: 1747 PGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLS 1805
P T P T P P GT+ P T + P P+ T +Q P T++
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVT 3541
Query: 1806 PEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
P T T P + T T T G P+ T++
Sbjct: 3542 PTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3585
Score = 105 bits (262), Expect = 5e-22
Identities = 140/645 (21%), Positives = 226/645 (35%), Gaps = 64/645 (9%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
PI ++ PT + T V+P P ++ + IT T + +
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPT 3338
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP--------PNFSHTGPTFPVVPPFLS 1341
P + + + ++ + T+ P T P P + TG P P +
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ PT P T+ P +T+V + T+ T+T VT P P
Sbjct: 3399 TTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTP 3454
Query: 1402 PVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS-- 1459
+++P + + ++ T V+ + T Q PT+T + ++T + P+ T + T
Sbjct: 3455 TGTQTPTTTPITTTTT----VTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTT 3508
Query: 1460 ---AGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTP 1516
+T TP P P + T T T ++TTT+ T + Q + T+TP
Sbjct: 3509 TPITTTTTVTPTPTP----------TGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTP 3556
Query: 1517 TLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVI 1576
T V + T +TT + + + + + G +Q P+ + +
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTTV 3609
Query: 1577 ASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVANVPAVQQTLIHSQPQ-PAL 1626
TP PT+TP+ P P P+ V T + Q P
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669
Query: 1627 LPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIES 1686
P T + T + P I T ++ + +G Q + T + +
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTPTGTQTPTT---TPITTTT 3722
Query: 1687 TVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVK 1746
TVTP T TT+T + PT P GT TP+ T V TP T T
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3781
Query: 1747 PGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLS 1805
P T P T P P GT+ P T + P P+ T +Q P T++
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVT 3840
Query: 1806 PEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
P T T P + T T T G P+ T++
Sbjct: 3841 PTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3884
Score = 104 bits (259), Expect = 1e-21
Identities = 120/526 (22%), Positives = 185/526 (35%), Gaps = 45/526 (8%)
Query: 1348 TTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESP 1407
TT P P T++P I+T+ + PT T T P P +++P
Sbjct: 1886 TTTTTENPTPPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1942
Query: 1408 VLSSVVSSITI-----------PAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSAT 1456
+ + ++ T+ P I+TT+ PT T ++T + + TV+ T
Sbjct: 1943 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2002
Query: 1457 SASAGGSTATPGP-KPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTST 1515
G T T P V+ + T T T ++TTT+ T + Q + T+T
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTT 2060
Query: 1516 PTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSV 1575
P T V + T +TT + + + + + G +Q P+ +
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTT 2113
Query: 1576 IASTPILPQAAGPTSTPLLPQVPSIP---------PLVQPVANVPAVQQTLIHSQPQ-PA 1625
+ TP PT+TP+ P P P+ V T + Q P
Sbjct: 2114 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2173
Query: 1626 LLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIE 1685
P T + T + P I T ++ + +G Q + T +
Sbjct: 2174 TTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPTPTGTQTPTT---TPITTT 2226
Query: 1686 STVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGV 1745
+TVTP T TT+T + PT P GT TP+ T V TP T T
Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQ 2285
Query: 1746 KPGTAPSKPPLTKAPV-LPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTL 1804
P T P T P P GT+ P T + P P+ T +Q P T+
Sbjct: 2286 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTV 2344
Query: 1805 SPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSS 1850
+P T T P + T T T G P+ T++
Sbjct: 2345 TPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2389
Score = 96.3 bits (238), Expect = 3e-19
Identities = 117/440 (26%), Positives = 168/440 (38%), Gaps = 73/440 (16%)
Query: 1316 TEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEV 1375
T P T P+ T T +PP ++ PTT T P T SPP I+T+
Sbjct: 1398 TPSPPTTTPSPPPTSTT--TLPP--TTTPSPPTTTTTTPPPTTTPSPP--ITTTTTPPPT 1451
Query: 1376 TVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSP---SLQ 1432
T P+ ++T+T P P + SP ++ T P+ + +TT+P +
Sbjct: 1452 TTPSPP----ISTTT-------TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP 1500
Query: 1433 VPTSTSEIV--VSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLT 1490
P +T+ I S+T L P+ T S + + T P PP STT T
Sbjct: 1501 SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560
Query: 1491 SVS---TTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAP 1547
+ S TTT+ P + S +++ S PT+ T P
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT------------------------P 1596
Query: 1548 SSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPV 1607
+++P ++ + P P PS +TPI P PTST LP P+ P P
Sbjct: 1597 PPTTTPSPPTTTTTTPP----PTTTPSPPTTTPITP----PTSTTTLP--PTTTPSPPPT 1646
Query: 1608 ANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHS 1667
T P P+ P T T P +P I T + + S
Sbjct: 1647 TTTTPPPTTT--PSPPTTTTPSPPITTTTTPPPTTTPSSP----ITTTPSPPTTTMTTPS 1700
Query: 1668 SSGAQHASVSLETSLVIESTVTPG-IPTTAVAPSKLLT----STTSTCLPPTNLPLGTVA 1722
+ + ++ T+ ST TP PTT PS T +TT T LPPT
Sbjct: 1701 PTTTPSSPIT--TTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758
Query: 1723 LPVTPVVTPGQVSTPVSTTT 1742
P+ P +TP S P STTT
Sbjct: 1759 TPLPPSITPPTFS-PFSTTT 1777
Score = 93.6 bits (231), Expect = 2e-18
Identities = 115/496 (23%), Positives = 175/496 (35%), Gaps = 41/496 (8%)
Query: 1374 EVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSIT-------IPAVVSIST 1426
E+ V E + T T T P PP + +P+ ++ + T P I+T
Sbjct: 1870 EINVQCCECVTQPTTMTTTTTEN--PTPPTT-TPITTTTTVTPTPTPTGTQTPTTTPITT 1926
Query: 1427 TSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGP-KPPAVVSQQAAGSTTV 1485
T+ PT T ++T + + TV+ T G T T P V+ + T
Sbjct: 1927 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1986
Query: 1486 GATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLS 1545
T T ++TTT+ T + Q + T+TP T V + T +TT + + +
Sbjct: 1987 TPTTTPITTTTTVTPTPTPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2044
Query: 1546 APSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIP---- 1601
+ + G +Q P+ + + TP PT+TP+ P
Sbjct: 2045 VTPTPTPTG-------TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2097
Query: 1602 -----PLVQPVANVPAVQQTLIHSQPQ-PALLPNQPHTHCPEVDSDTQPKAPGIDDIKTL 1655
P P+ V T + Q P P T + T + P I T
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT- 2156
Query: 1656 EEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTN 1715
++ + +G Q + T + +TVTP T TT+T + PT
Sbjct: 2157 ---TTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210
Query: 1716 LPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPV-LPVGTELPAGTLP 1774
P GT TP+ T V TP T T P T P T P P GT+ P T
Sbjct: 2211 TPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2269
Query: 1775 SEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQ 1834
+ P P+ T +Q P T++P T T P + T T T
Sbjct: 2270 TTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTP 2327
Query: 1835 KGVSQVKEGPVLATSS 1850
G P+ T++
Sbjct: 2328 TGTQTPTTTPITTTTT 2343
Score = 86.3 bits (212), Expect = 3e-16
Identities = 124/583 (21%), Positives = 205/583 (35%), Gaps = 73/583 (12%)
Query: 1230 PIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS 1289
PI ++ PT + T V+P P ++ + IT T + +
Sbjct: 3855 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPT 3913
Query: 1290 PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAP--------PNFSHTGPTFPVVPPFLS 1341
P + + + ++ + T+ P T P P + TG P P +
Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973
Query: 1342 SIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIP 1401
+ PT P T+ P +T+V + T+ T+T VT P P
Sbjct: 3974 TTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTP 4029
Query: 1402 PVSESPVLSSVVSSITI-----------PAVVSISTTSPSLQVPTSTSEIVVSSTALYPS 1450
+++P + + ++ T+ P I+TT+ PT T ++T + +
Sbjct: 4030 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4089
Query: 1451 VTVSATSASAGGSTATPGP-KPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQL 1509
TV+ T G T T P V+ + T T T ++TTT+ T + Q
Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ- 4148
Query: 1510 SSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHP 1569
+ T+TP T V + T +TT + + + + + G + P
Sbjct: 4149 -TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG----TQTGPPTHTST 4203
Query: 1570 LVIPSVIASTP----ILPQAAGPTSTPLLPQ---VPSIPPLVQPVANVPAVQQTLIHSQP 1622
I + S P PQ + TS+PL + ++PP ++ + P S P
Sbjct: 4204 APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP-------STP 4256
Query: 1623 QPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTL----EEKLRSLFSEHSSSGAQHASVSL 1678
+ HT P + T P PG T S ++S L
Sbjct: 4257 TAPTTTSGGHTLSPPPSTTTSP--PGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPL 4314
Query: 1679 ETSLVIESTVTPGIPTTAV----------APSKLLTSTTS-------TCLPPTNLPLGTV 1721
T +I +T P++ + AP + + + T C L
Sbjct: 4315 STPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNW 4374
Query: 1722 ALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKP-PLTKAPVLP 1763
+ P TP TP TP +T + KP + PSKP P TK P P
Sbjct: 4375 SCPSTPSPTP----TPSKSTPTPSKPSSTPSKPTPGTKPPECP 4413
Score = 64.3 bits (155), Expect = 1e-09
Identities = 95/441 (21%), Positives = 139/441 (31%), Gaps = 82/441 (18%)
Query: 1510 SSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHP 1569
S T+TP+ T + S +TT + P +++P +++ + P P
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTT-----TTTPPPTTTPSPPITTTTTPP----P 1450
Query: 1570 LVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPN 1629
PS ST P PT+TP P PP P T + P P P+
Sbjct: 1451 TTTPSPPISTTTTPP---PTTTPSPPTTTPSPPTTTPSP------PTTTTTTPPPTTTPS 1501
Query: 1630 QPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVT 1689
P T + P A ++ + T T
Sbjct: 1502 PPTT------TPITPPA---------------------------------STTTLPPTTT 1522
Query: 1690 PGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTP-----VVTPGQVSTPVSTTTSG 1744
P PT TT+T PPT P P+TP + P +P TTT+
Sbjct: 1523 PSPPT-----------TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1571
Query: 1745 VKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTL 1804
P T PS PP T P P T T P P P + T + P +
Sbjct: 1572 PPPTTTPS-PPTTTTPSPPTITT----TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626
Query: 1805 SPEMITVTSAVGPVSMAAPTAIT--EAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQV 1862
+P T T PT T T P + P+ T++
Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPIT 1686
Query: 1863 SVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVP 1922
+ + S ++T+ SS + S P +T+ P P T P +
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT--TTPSPPTTTM 1744
Query: 1923 ESAHKTTASEAKSDTGQPTKV 1943
+ TT S + T P +
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSI 1765
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2228
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 2229 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2287
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 2288 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2347
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 2348 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 2401
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 2522 ITTTTTV 2528
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2412
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 2413 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2471
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 2472 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2531
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 2532 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 2585
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 2706 ITTTTTV 2712
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2537
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 2538 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2596
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 2597 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 2716 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 2769
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 2890 ITTTTTV 2896
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2780
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 2781 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2839
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2899
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 2900 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 2953
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 3074 ITTTTTV 3080
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 2965 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3023
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3083
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 3084 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3137
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 3258 ITTTTTV 3264
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3148
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 3149 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3207
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 3208 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3267
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 3268 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3321
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 3442 ITTTTTV 3448
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3332
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 3333 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3391
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3451
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 3452 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3505
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 3626 ITTTTTV 3632
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 3517 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3575
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3635
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 3636 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3689
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3809
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 3810 ITTTTTV 3816
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3700
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 3701 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3759
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 3760 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3819
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 3820 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 3873
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3933
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 3934 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 3994 ITTTTTV 4000
Score = 60.1 bits (144), Expect = 3e-08
Identities = 101/487 (20%), Positives = 163/487 (33%), Gaps = 39/487 (8%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 3708 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3884
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 3885 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003
Query: 895 QLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQY 954
PT TQ P+ P V P P+++ + P Q
Sbjct: 4004 PTPT----GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT 4057
Query: 955 PGDSNIAPSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVP 1006
P + I ++ V + +P P+ T TP PT Q P + + P
Sbjct: 4058 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117
Query: 1007 M-GGVGGQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQP 1061
G Q + P ++ PT T +Q + V P QT T P
Sbjct: 4118 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4177
Query: 1062 TTLASSV 1068
T ++V
Sbjct: 4178 ITTTTTV 4184
Score = 59.3 bits (142), Expect = 4e-08
Identities = 82/401 (20%), Positives = 132/401 (32%), Gaps = 28/401 (6%)
Query: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVS 670
TG T +TT + +T V P Q P + + + G+ T + ++
Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949
Query: 671 SQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA-----------QGQSQ 719
+ TV+ + T P +TV P G P++
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009
Query: 720 GQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQA 779
P+++ +T ++ P P Q T P T + + T T ++ T P++
Sbjct: 4010 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068
Query: 780 PQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLL 836
P G Q P + P+ T P T P+ P+ + P P T
Sbjct: 4069 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4127
Query: 837 PQYPVSQIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPS 894
P++ TP + T ++ PIT +T P T + TT I +TV P+
Sbjct: 4128 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4187
Query: 895 QLPTLLQ--PVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRL-- 950
PT Q P T + +L ++ PL+ L PP +
Sbjct: 4188 PTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247
Query: 951 ----PPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLAT 987
PP P + S +T P PT T
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT 4288
Score = 56.6 bits (135), Expect = 3e-07
Identities = 99/481 (20%), Positives = 161/481 (33%), Gaps = 39/481 (8%)
Query: 606 LPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFT 665
+ + +T PT TT+ +T P Q P + + + G+ T
Sbjct: 1885 MTTTTTENPTPPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1943
Query: 666 ESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSS 725
+ +++ TV+ + T P +TV P G P++ +
Sbjct: 1944 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT------------T 1991
Query: 726 SLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQ 785
+T ++ P P Q T P T + + T T ++ T P++ P
Sbjct: 1992 PITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP- 2049
Query: 786 VSAGKQLPVSQPVPTIQGEPQIPVAT---QPSVVPVHSGAHFLPVGQPLPTPLLPQYPVS 842
G Q P + P+ T P T P+ P+ + P P T P++
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109
Query: 843 QIPISTPHVSTAQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPSQLPTLL 900
TP + T ++ PIT +T P T + TT I +TV P+ PT
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-- 2167
Query: 901 QPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNI 960
TQ P+ P V P P+++ + P Q P + I
Sbjct: 2168 --GTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI 2223
Query: 961 APSSNVASVCIHSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVPM-GGVG 1011
++ V + +P P+ T TP PT Q P + + P G
Sbjct: 2224 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2283
Query: 1012 GQVQVSQP---GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASS 1067
Q + P ++ PT T +Q + V P QT T P T ++
Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2343
Query: 1068 V 1068
V
Sbjct: 2344 V 2344
Score = 54.7 bits (130), Expect = 1e-06
Identities = 83/363 (22%), Positives = 112/363 (30%), Gaps = 38/363 (10%)
Query: 709 PPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEA 768
PP+S PS + T ++ P P T PP T +S T+T
Sbjct: 1409 PPTSTTTLPPTTTPSPPTTT-TTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPT 1467
Query: 769 TT-AQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPV 827
TT + P + P P P + + P PT P T + P S P
Sbjct: 1468 TTPSPPTTTPSPPTTTP---SPPTTTTTTPPPTTTPSP----PTTTPITPPASTTTLPPT 1520
Query: 828 GQPLP----TPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTA 883
P P T P P +TP T T ++LP T T TT
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSPPTTTP--ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1578
Query: 884 AIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLY 943
+ P +T P + T P T PS P + P P +S L
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT--TTPITPPTSTTTL- 1635
Query: 944 QGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNL 1003
PP P P + P +T SPP+ T P P+ S
Sbjct: 1636 ---PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPP 1692
Query: 1004 LVPMGGVGGQVQVSQPGGSLAQAPTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTT 1063
M +PTT+ + +T S P+ P T + PTT
Sbjct: 1693 TTTM---------------TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS--PTT 1735
Query: 1064 LAS 1066
S
Sbjct: 1736 TPS 1738
Score = 54.3 bits (129), Expect = 1e-06
Identities = 71/349 (20%), Positives = 111/349 (31%), Gaps = 39/349 (11%)
Query: 748 TAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQI 807
T P T +L T+T S TT P P + P + P P I
Sbjct: 1405 TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTP 1464
Query: 808 PVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAA 867
P T PS P P P P P + +TP +T + ++ PIT
Sbjct: 1465 PPTTTPSP----------PTTTPSPPTTTPSPPTT--TTTTPPPTTTPSPPTTTPIT--- 1509
Query: 868 GITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPAN 927
A+T +P +T P T P T PS + P + +P
Sbjct: 1510 ----------PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559
Query: 928 LGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLAT 987
+ ++ PP P P + +P + + +T SPP T
Sbjct: 1560 TTPSPPPTTTTTP------PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP 1613
Query: 988 PGYFP-----TVVQPYVESNLLVPMGGVG-GQVQVSQPGGSLAQAP--TTSSQQAVLEST 1039
P P T + P + L P + P + +P TT+ + +T
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 1040 QGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPS 1088
P+ P+ + T T S + S + + + + PS
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPS 1722
Score = 49.3 bits (116), Expect = 5e-05
Identities = 75/331 (22%), Positives = 105/331 (31%), Gaps = 45/331 (13%)
Query: 686 STGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTG---VSSSQPIQHPQQQ 742
ST T P P T PP++ + P++++ T + S P P
Sbjct: 1459 STTTTP---PPTTTPSPPTTTPSPPTT-----TPSPPTTTTTTPPPTTTPSPPTTTPITP 1510
Query: 743 QGIQQTAPPQQTVQYSLSQTSTSSEATTAQP-----VSQPQAPQVLPQVSAGKQLPVSQP 797
T PP T + T+T TT P ++ P + LP + P +
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 798 VPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLP----TPLLPQYPVSQIPISTPHVST 853
P P P T PS P + P P P T P P +TP T
Sbjct: 1571 TPPPTTTPSPPTTTTPS-PPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP--IT 1627
Query: 854 AQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQ 913
T ++LP T T TT + P +T P T P T PS
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT 1687
Query: 914 LLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHS 973
P +M P+ P P P + PSS +
Sbjct: 1688 TPSPPTTTMTTPS---------------------PTTTPSSPITTTTTPSS-TTTPSPPP 1725
Query: 974 TVLSPPMPTEVLATPGYFPTVVQPYVESNLL 1004
T ++ P PT + P T + P S+ L
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPL 1756
Score = 48.5 bits (114), Expect = 8e-05
Identities = 65/320 (20%), Positives = 95/320 (29%), Gaps = 18/320 (5%)
Query: 695 PSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQT 754
P + P P ++ + ++ S + S P P T PP T
Sbjct: 1440 PPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT 1499
Query: 755 VQYSLSQTSTSSEATTAQP----VSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVA 810
+ T +TT P S P P + P + P+ +P
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559
Query: 811 TQPSVVPVHSGAHFLPVGQPLPTPLLPQYP----VSQIPISTPHVSTAQTGFSSLPITMA 866
T PS P + PT P P + P +TP T T T +
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619
Query: 867 AGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPA 926
T P+ S+ T +P +T P T P T PS P + + P
Sbjct: 1620 PPTTTPITPPTSTTT---LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP- 1675
Query: 927 NLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLA 986
S + PP P + PSS + + S+ +P P +
Sbjct: 1676 -----PPTTTPSSPITTTPSPPTTTMTTPSPTT-TPSSPITTTTTPSSTTTPSPPPTTMT 1729
Query: 987 TPGYFPTVVQPYVESNLLVP 1006
TP T P L P
Sbjct: 1730 TPSPTTTPSPPTTTMTTLPP 1749
Score = 39.3 bits (90), Expect = 0.047
Identities = 65/290 (22%), Positives = 99/290 (34%), Gaps = 23/290 (7%)
Query: 794 VSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVST 853
V+QP + P T P+ P+ + P P T P++ TP +
Sbjct: 1879 VTQPTTMTTTTTENP--TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1936
Query: 854 AQTGF-SSLPITMAAGITQ-PLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVH 911
T ++ PIT +T P T + TT I +TV P+ PT TQ P+
Sbjct: 1937 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTT- 1991
Query: 912 PQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCI 971
P V P P+++ + P Q P + I ++ V
Sbjct: 1992 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 2050
Query: 972 HSTVLSP---PMPTEVLATPGYFPTVVQ-----PYVESNLLVPM-GGVGGQVQVSQP--- 1019
+ +P P+ T TP PT Q P + + P G Q + P
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110
Query: 1020 GGSLAQAPT-TSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSV 1068
++ PT T +Q + V P QT T P T ++V
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160
Score = 38.9 bits (89), Expect = 0.061
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 2/117 (1%)
Query: 1710 CLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTEL- 1768
C P + + T + P T P +T + TT+ P T + PP T P P+ T
Sbjct: 1388 CCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447
Query: 1769 -PAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPT 1824
P T PS + P T + P + T SP T T+ + + PT
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT 1504
Score = 33.1 bits (74), Expect = 3.3
Identities = 20/85 (23%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 96 PGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPST 155
P + P P+ + P + P P T T T+ + +P + P+P+T
Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703
Query: 156 VPSSTSKDRPVSQPSLVGSKEEPPP 180
PSS P++ + S P P
Sbjct: 1704 TPSS-----PITTTTTPSSTTTPSP 1723
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 4/96 (4%)
Query: 90 ATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVA 149
A+ LP P + P + P P +T TS P +P
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP-TSTTTLPPTTTPSPPPTTTT 1570
Query: 150 GPAPSTVPSSTSKDRPVSQPSLVGSKEEPPPARSGS 185
P P+T PS + P S P++ + PPP + S
Sbjct: 1571 TPPPTTTPSPPTTTTP-SPPTI--TTTTPPPTTTPS 1603
Score = 31.6 bits (70), Expect = 9.7
Identities = 21/89 (23%), Positives = 30/89 (33%), Gaps = 3/89 (3%)
Query: 95 LPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPS 154
LP P P+ P + P P T + + P +P P P+
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT 1615
Query: 155 TVPS---STSKDRPVSQPSLVGSKEEPPP 180
T PS +T P S +L + PP
Sbjct: 1616 TTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644
>gi|85838511 mitogen-activated protein kinase kinase kinase 2 [Homo
sapiens]
Length = 619
Score = 108 bits (270), Expect = 6e-23
Identities = 83/264 (31%), Positives = 133/264 (50%), Gaps = 22/264 (8%)
Query: 227 IGRGSFKTVYKGLDTETTVEVAWCELQ---DRKLTKSERQRFKEEAEMLKGLQHPNIVRF 283
+G+G+F VY D +T E+A ++Q D T E + E ++LK L H IV++
Sbjct: 362 LGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQY 421
Query: 284 YDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTP 343
Y + K + + E M G++K LK + + V R + RQIL+G+ +LH+
Sbjct: 422 YGCLRDPQE--KTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNM- 478
Query: 344 PIIHRDLKCDNIFITGPTGSVKIGDLG----LATL-KRASFAKSVIGTPEFMAPEMYE-E 397
I+HRD+K NI + TG+VK+GD G L T+ + KSV GTP +M+PE+ E
Sbjct: 479 -IVHRDIKGANI-LRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGE 536
Query: 398 KYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIE 457
Y D+++ ++EM T + P++E + A I++ T P P V +
Sbjct: 537 GYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPK-----LPPHVSDYTR 591
Query: 458 GCIRQNKDE---RYSIKDLLNHAF 478
+++ E R S +LL H F
Sbjct: 592 DFLKRIFVEAKLRPSADELLRHMF 615
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.124 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,723,071
Number of Sequences: 37866
Number of extensions: 5654412
Number of successful extensions: 58821
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 380
Number of HSP's successfully gapped in prelim test: 2180
Number of HSP's that attempted gapping in prelim test: 28872
Number of HSP's gapped (non-prelim): 18712
length of query: 2382
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2263
effective length of database: 13,741,464
effective search space: 31096933032
effective search space used: 31096933032
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.