Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 148536848
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
(756 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 1576 0.0
gi|51593088 neuroligin 3 [Homo sapiens] 286 6e-77
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 283 4e-76
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 283 4e-76
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 281 2e-75
gi|30840978 neuroligin 2 [Homo sapiens] 280 4e-75
gi|7662470 neuroligin 1 [Homo sapiens] 275 9e-74
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 268 1e-71
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 265 9e-71
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 261 2e-69
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 236 8e-62
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 234 2e-61
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 234 3e-61
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 233 4e-61
gi|33563374 carboxylesterase 3 [Homo sapiens] 230 3e-60
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 216 6e-56
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 204 2e-52
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 200 5e-51
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 199 8e-51
gi|55770862 thyroglobulin [Homo sapiens] 157 3e-38
gi|160707881 formin 2 [Homo sapiens] 155 2e-37
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 126 7e-29
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 126 7e-29
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 116 9e-26
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 116 9e-26
gi|11386183 WAS protein family, member 2 [Homo sapiens] 97 6e-20
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 96 1e-19
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 96 1e-19
gi|116284392 mucin 2 precursor [Homo sapiens] 94 5e-19
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 92 2e-18
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 1576 bits (4080), Expect = 0.0
Identities = 756/756 (100%), Positives = 756/756 (100%)
Query: 1 MLTMGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAA 60
MLTMGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAA
Sbjct: 1 MLTMGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAA 60
Query: 61 PTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRD 120
PTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRD
Sbjct: 61 PTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRD 120
Query: 121 LPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDAN 180
LPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDAN
Sbjct: 121 LPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDAN 180
Query: 181 LPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAI 240
LPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAI
Sbjct: 181 LPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAI 240
Query: 241 SQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGL 300
SQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGL
Sbjct: 241 SQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGL 300
Query: 301 EYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNK 360
EYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNK
Sbjct: 301 EYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNK 360
Query: 361 KVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPT 420
KVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPT
Sbjct: 361 KVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPT 420
Query: 421 EIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQD 480
EIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQD
Sbjct: 421 EIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQD 480
Query: 481 RTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTN 540
RTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTN
Sbjct: 481 RTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTN 540
Query: 541 FLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTG 600
FLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTG
Sbjct: 541 FLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTG 600
Query: 601 DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP 660
DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP
Sbjct: 601 DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP 660
Query: 661 PVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPT 720
PVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPT
Sbjct: 661 PVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPT 720
Query: 721 GDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF 756
GDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF
Sbjct: 721 GDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF 756
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 286 bits (731), Expect = 6e-77
Identities = 222/682 (32%), Positives = 305/682 (44%), Gaps = 110/682 (16%)
Query: 3 TMGR-LQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFA 59
T+GR L L + L+ ++ A V T G + G L +LG VD + G+P+A
Sbjct: 17 TVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGP-VDQYLGVPYA 75
Query: 60 APT---KALENPQPHPGWQGTLKAKNFKKRCLQ----------------ATITQDSTY-- 98
AP K P+P P W G A +F C Q A + +TY
Sbjct: 76 APPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQ 135
Query: 99 -GDEDCLYLNIWVP----QGRKQVSRDL-----------------PVMIWIYGGAFLMGS 136
+EDCLYLN++VP G K+ DL PVM++I+GG+++ G+
Sbjct: 136 EPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGT 195
Query: 137 GHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAW 196
G+ + DG +A+ GNVIV+T NYRVG LGFLSTGD GNYGL DQ A+ W
Sbjct: 196 GN--------MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW 247
Query: 197 VKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNP 256
V NIA FGGDP IT+FG G + VSL TLS +++GL +RAI QSG ALS W + P
Sbjct: 248 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP 307
Query: 257 LFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDG 316
+ + +A+KVGC V D M CL+ + L + P ++V F PVIDG
Sbjct: 308 VKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL-------VEQDIQPARYHVAFGPVIDG 360
Query: 317 DFIPADPINLYANAADIDY--IAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEF 374
D IP DP L ++Y + G N +G F + + V+ DF VS F
Sbjct: 361 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKF----VEGVVDPEDGVSGTDFDYSVSNF 416
Query: 375 T-----ITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRA 429
+G + T WA + E ++KT+V TD ++ P+ + H
Sbjct: 417 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHA- 475
Query: 430 NAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRP-----QDRTVS 484
+ TY Y F H + + P W A H D++ YVFG P PT P D +S
Sbjct: 476 -RYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLS 534
Query: 485 KAMIAYWTNFAKTGDPN------------MGDSAVPTHWEPYTTENSGYLEITKKMGSSS 532
++ YWTNFAKTGDPN + W Y + YL I K
Sbjct: 535 AVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRD 594
Query: 533 MKRSLRTNFLRYW---------------TLTYLALPTVTDQEATPVPPTGDSEATPVP-- 575
R+ + F ++ T T + P T P G + +T P
Sbjct: 595 HYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAI 654
Query: 576 -PTGDSETAPVPPTGDSGAPPV 596
P +E A GD A P+
Sbjct: 655 SPAYSNENAQGSWNGDQDAGPL 676
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 283 bits (724), Expect = 4e-76
Identities = 187/522 (35%), Positives = 264/522 (50%), Gaps = 63/522 (12%)
Query: 20 VASAAKLGAVYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAPT---KALENPQPHPGW 74
+ S A+ V T G + G+ L +LG V+ + G+P+A+P + + P+P W
Sbjct: 39 IDSQAQYPVVNTNYGKIRGLRTPLPNEILGP-VEQYLGVPYASPPTGERRFQPPEPPSSW 97
Query: 75 QGTLKAKNFKKRCLQ-----------------ATITQDSTY---GDEDCLYLNIWVPQG- 113
G F C Q A + TY +EDCLYLNI+VP
Sbjct: 98 TGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTED 157
Query: 114 --RKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPL 171
Q S+ PVM++I+GG+++ G+G+ + DG +A+ GNVIV+T NYR+G L
Sbjct: 158 DIHDQNSKK-PVMVYIHGGSYMEGTGN--------MIDGSILASYGNVIVITINYRLGIL 208
Query: 172 GFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPY 231
GFLSTGD GNYGL DQ A+ W++ N+ AFGGDP +T+FG AG + VSL TLS Y
Sbjct: 209 GFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHY 268
Query: 232 NKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTL 291
++GL ++AI QSG ALS W + P + + +A+KVGC + D M +CL+ +
Sbjct: 269 SEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKN------ 322
Query: 292 AYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNNMDGHIFAS 349
YK + P +++ F PVIDGD IP DP L ++Y + G N +G F
Sbjct: 323 -YKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF-- 379
Query: 350 IDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQDPSQENKK 404
+ I VT DF VS F +G + T WA + E ++
Sbjct: 380 --VDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR 437
Query: 405 KTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQY 464
KT+V TD ++ P +A A A S TY Y F H + + P W + H D++ Y
Sbjct: 438 KTLVALFTDHQWVAPA-VATADLHAQYGS-PTYFYAFYHHCQSEMKPSWADSAHGDEVPY 495
Query: 465 VFGKPFATPT-----GYRPQDRTVSKAMIAYWTNFAKTGDPN 501
VFG P PT + D +S ++ YWTNFAKTGDPN
Sbjct: 496 VFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 283 bits (724), Expect = 4e-76
Identities = 187/522 (35%), Positives = 264/522 (50%), Gaps = 63/522 (12%)
Query: 20 VASAAKLGAVYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAPT---KALENPQPHPGW 74
+ S A+ V T G + G+ L +LG V+ + G+P+A+P + + P+P W
Sbjct: 39 IDSQAQYPVVNTNYGKIRGLRTPLPNEILGP-VEQYLGVPYASPPTGERRFQPPEPPSSW 97
Query: 75 QGTLKAKNFKKRCLQ-----------------ATITQDSTY---GDEDCLYLNIWVPQG- 113
G F C Q A + TY +EDCLYLNI+VP
Sbjct: 98 TGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTED 157
Query: 114 --RKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPL 171
Q S+ PVM++I+GG+++ G+G+ + DG +A+ GNVIV+T NYR+G L
Sbjct: 158 DIHDQNSKK-PVMVYIHGGSYMEGTGN--------MIDGSILASYGNVIVITINYRLGIL 208
Query: 172 GFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPY 231
GFLSTGD GNYGL DQ A+ W++ N+ AFGGDP +T+FG AG + VSL TLS Y
Sbjct: 209 GFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHY 268
Query: 232 NKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTL 291
++GL ++AI QSG ALS W + P + + +A+KVGC + D M +CL+ +
Sbjct: 269 SEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKN------ 322
Query: 292 AYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNNMDGHIFAS 349
YK + P +++ F PVIDGD IP DP L ++Y + G N +G F
Sbjct: 323 -YKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF-- 379
Query: 350 IDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQDPSQENKK 404
+ I VT DF VS F +G + T WA + E ++
Sbjct: 380 --VDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR 437
Query: 405 KTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQY 464
KT+V TD ++ P +A A A S TY Y F H + + P W + H D++ Y
Sbjct: 438 KTLVALFTDHQWVAPA-VATADLHAQYGS-PTYFYAFYHHCQSEMKPSWADSAHGDEVPY 495
Query: 465 VFGKPFATPT-----GYRPQDRTVSKAMIAYWTNFAKTGDPN 501
VFG P PT + D +S ++ YWTNFAKTGDPN
Sbjct: 496 VFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 281 bits (719), Expect = 2e-75
Identities = 187/525 (35%), Positives = 264/525 (50%), Gaps = 69/525 (13%)
Query: 20 VASAAKLGAVYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAPT---KALENPQPHPGW 74
+ S A+ V T G ++G+ L +LG V+ + G+P+A+P + + P+ W
Sbjct: 39 IDSQAQYPVVNTNYGKIQGLRTPLPSEILGP-VEQYLGVPYASPPTGERRFQPPESPSSW 97
Query: 75 QGTLKAKNFKKRCLQ-----------------------ATITQDSTYGDEDCLYLNIWVP 111
G A F C Q T QD +EDCLYLNI+VP
Sbjct: 98 TGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQ---NEDCLYLNIYVP 154
Query: 112 QG---RKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRV 168
+Q S+ PVM++I+GG+++ G+G+ + DG +A+ GNVIV+T N R+
Sbjct: 155 MEDDIHEQNSKK-PVMVYIHGGSYMEGTGN--------MIDGSILASYGNVIVITINCRL 205
Query: 169 GPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTL 228
G LGFLSTGD GNYGL DQ A+ W++ N+ AFGGDP +T+FG AG + VSL TL
Sbjct: 206 GILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTL 265
Query: 229 SPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRA 288
S Y++GL ++AI QSG ALS W + P + + +A+KVGC + D M +CLK +
Sbjct: 266 SHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKN--- 322
Query: 289 LTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNNMDGHI 346
YK + P +++ F PVIDGD IP DP L ++Y + G N +G
Sbjct: 323 ----YKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLK 378
Query: 347 FASIDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQDPSQE 401
F + I VT DF VS F +G + T WA + E
Sbjct: 379 F----VDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPE 434
Query: 402 NKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADD 461
++KT+V TD ++ P +A A A S TY Y F H + + P W + H D+
Sbjct: 435 TRRKTLVALFTDHQWVAPA-VATADLHAQYGS-PTYFYAFYHHCQSEMKPSWADSAHGDE 492
Query: 462 IQYVFGKPFATPT-----GYRPQDRTVSKAMIAYWTNFAKTGDPN 501
+ YVFG P PT + D +S ++ YWTNFAKTGDPN
Sbjct: 493 VPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 280 bits (716), Expect = 4e-75
Identities = 242/817 (29%), Positives = 345/817 (42%), Gaps = 138/817 (16%)
Query: 29 VYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAP---TKALENPQPHPGWQGTLKAKNF 83
V T G V GV ++L +LG V F G+P+A P + + P+ W G A
Sbjct: 44 VNTAYGRVRGVRRELNNEILGPVVQ-FLGVPYATPPLGARRFQPPEAPASWPGVRNATTL 102
Query: 84 KKRCLQ----------------------ATITQDSTYGDEDCLYLNIWVP--QGRKQVSR 119
C Q AT Q+ + EDCLYLN++VP G R
Sbjct: 103 PPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQS---EDCLYLNLYVPTEDGPLTKKR 159
Query: 120 D----------------LPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVT 163
D PVM++++GG+++ G+G+ ++DG +A GNVIV T
Sbjct: 160 DEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGN--------MFDGSVLAAYGNVIVAT 211
Query: 164 FNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASV 223
NYR+G LGFLSTGD GNYGL DQ A+ W+ NIA FGGDP IT+FG AG + V
Sbjct: 212 LNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCV 271
Query: 224 SLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKV 283
+L LS +++GL ++AI+QSG A+S W + PL + + +A KVGC D+A +CL+
Sbjct: 272 NLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRR 331
Query: 284 TDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNN 341
R L + P +++ F PV+DGD +P DP L ++Y + G N
Sbjct: 332 KPSREL-------VDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQ 384
Query: 342 MDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQ 396
+G F ++ A ++ + DF VS F +G + T WA
Sbjct: 385 GEGLKF--VEDSAESEDGVSASAFDF--TVSNFVDNLYGYPEGKDVLRETIKFMYTDWAD 440
Query: 397 DPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGA 456
+ E ++KT++ TD ++ P +A A+ A+ +S Y Y F H + P+W A
Sbjct: 441 RDNGEMRRKTLLALFTDHQWVAPA-VATAKLHADYQS-PVYFYTFYHHCQAEGRPEWADA 498
Query: 457 DHADDIQYVFGKPFA-----TPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTH- 510
H D++ YVFG P P + D +S ++ YWTNFAKTGDPN VP
Sbjct: 499 AHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN---QPVPQDT 555
Query: 511 --------------WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYW--TLTYL-ALP 553
W + ++ YL I K ++ + R N + +W + +L L
Sbjct: 556 KFIHTKPNRFEEVVWSKFNSKEKQYLHIGLK---PRVRDNYRANKVAFWLELVPHLHNLH 612
Query: 554 TVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 613
T T +PP + P PP G T PP P P G P
Sbjct: 613 TELFTTTTRLPPYA-TRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRD 671
Query: 614 GAPPVPPTGDSGAPPV--------------------------PPTGD-SGAPPVPPTGDS 646
+ + T GA + PP G SG P P +
Sbjct: 672 YSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPA 731
Query: 647 GAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPV 706
+PP + + + G GA P A PP AP P GA +
Sbjct: 732 AGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDY-TLALRRAPDDVPLLAPGALTL 790
Query: 707 TPTGDSETAPVPPTG---DSGAPPVPPTGDSEAAPVP 740
P+G P PP PP PPT S +P
Sbjct: 791 LPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLP 827
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 275 bits (704), Expect = 9e-74
Identities = 197/580 (33%), Positives = 272/580 (46%), Gaps = 91/580 (15%)
Query: 29 VYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAPT---KALENPQPHPGWQGTLKAKNF 83
V T G + G+ K+L +LG + F G+P+AAP + + P+P W A F
Sbjct: 55 VATNFGKIRGIKKELNNEILGPVIQ-FLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQF 113
Query: 84 KKRCLQATI-----------------------TQDSTYGDEDCLYLNIWVP--QGRKQVS 118
C Q I QD + EDCLYLNI+VP +
Sbjct: 114 APVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQS---EDCLYLNIYVPTEDDIRDSG 170
Query: 119 RDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGD 178
PVM++I+GG+++ G+G+ LYDG +A+ GNVIV+T NYR+G LGFLSTGD
Sbjct: 171 GPKPVMVYIHGGSYMEGTGN--------LYDGSVLASYGNVIVITVNYRLGVLGFLSTGD 222
Query: 179 ANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYN------ 232
GNYGL D A+ W NI FGGDP IT+FG AGG+ V+L TLS Y+
Sbjct: 223 QAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWS 282
Query: 233 ---KGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
KGL +RAI+QSG ALS W + P +A+ +A KVGC V D + +CL+
Sbjct: 283 NSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQ------- 335
Query: 290 TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNNMDGHIF 347
YK + P +++ F PVIDGD IP DP L ++Y + G N +G F
Sbjct: 336 KKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF 395
Query: 348 ASIDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQDPSQEN 402
+ I + ++ DF VS F +G + T WA + E
Sbjct: 396 ----VENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPET 451
Query: 403 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDI 462
++KT++ TD ++ P +A A +N S TY Y F H + P W A H D++
Sbjct: 452 RRKTLLALFTDHQWVAPA-VATADLHSNFGS-PTYFYAFYHHCQTDQVPAWADAAHGDEV 509
Query: 463 QYVFGKPFATPT-----GYRPQDRTVSKAMIAYWTNFAKTGDPNM------------GDS 505
YV G P PT + D +S ++ YWTNFAKTGDPN +
Sbjct: 510 PYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNR 569
Query: 506 AVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYW 545
W Y+ ++ YL I K +K R N + W
Sbjct: 570 FEEVAWTRYSQKDQLYLHIGLK---PRVKEHYRANKVNLW 606
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 268 bits (686), Expect = 1e-71
Identities = 187/580 (32%), Positives = 268/580 (46%), Gaps = 59/580 (10%)
Query: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKALEN---PQPHPGWQGTLKAKNFKK 85
V GG + G+ K G V F GIPFA P P+P W G + A F+
Sbjct: 41 VTVRGGRLRGIRLKTP--GGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98
Query: 86 RCLQATITQDSTYG-----------DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLM 134
C Q T + EDCLYLN+W P R + PV++WIYGG F
Sbjct: 99 VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRP--TSPTPVLVWIYGGGFYS 156
Query: 135 GSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLST-GDANLPGNYGLRDQHMA 193
G A+ L+ +YDG + ++V+ NYRVG GFL+ G PGN GL DQ +A
Sbjct: 157 G----ASSLD--VYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 194 IAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPW--V 251
+ WV+ N+AAFGGDP ++TLFGESAG ASV + LSP ++GL RA+ QSG PW V
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV 270
Query: 252 IQKNPLFWAKKVAEKVGCPV----GDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHY 307
A ++A VGCP G+ + CL+ T P + + ++ + L +
Sbjct: 271 GMGEARRRATQLAHLVGCPPGGTGGNDTELVACLR-TRPAQVLVNHEWHV--LPQESVFR 327
Query: 308 VGFVPVIDGDFIPADPINLYANAAD---IDYIAGTNNMDGHIFASIDMPAINKGNKKVTE 364
FVPV+DGDF+ P L NA D + + G +G F P +K N+
Sbjct: 328 FSFVPVVDGDFLSDTPEAL-INAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNE---- 382
Query: 365 EDFYKLVSEFTITKGLR-GAKTTFDVYTES-------WAQDPSQENKKKTVVDFETDVLF 416
L+S G+R G D+ E+ W ++ + D D
Sbjct: 383 ----SLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNV 438
Query: 417 LVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGY 476
+ P +A R A+ A+ YAY+F H + +P W+G H +I+++FG P Y
Sbjct: 439 VCP--VAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNY 496
Query: 477 RPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRS 536
+++ ++ ++ YW NFA+TGDPN W PYT Y+ + + ++R
Sbjct: 497 TAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSL--DLRPLEVRRG 554
Query: 537 LRTNFLRYWTLTYLALPTVTDQEA-TPVPPTGDSEATPVP 575
LR +W L + T EA + P EA P P
Sbjct: 555 LRAQACAFWNRFLPKLLSATASEAPSTCPGFTHGEAAPRP 594
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 265 bits (678), Expect = 9e-71
Identities = 181/561 (32%), Positives = 261/561 (46%), Gaps = 58/561 (10%)
Query: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKALEN---PQPHPGWQGTLKAKNFKK 85
V GG + G+ K G V F GIPFA P P+P W G + A F+
Sbjct: 41 VTVRGGRLRGIRLKTP--GGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98
Query: 86 RCLQATITQDSTYG-----------DEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLM 134
C Q T + EDCLYLN+W P R + PV++WIYGG F
Sbjct: 99 VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRP--TSPTPVLVWIYGGGFYS 156
Query: 135 GSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLST-GDANLPGNYGLRDQHMA 193
G A+ L+ +YDG + ++V+ NYRVG GFL+ G PGN GL DQ +A
Sbjct: 157 G----ASSLD--VYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 194 IAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPW--V 251
+ WV+ N+AAFGGDP ++TLFGESAG ASV + LSP ++GL RA+ QSG PW V
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATV 270
Query: 252 IQKNPLFWAKKVAEKVGCPV----GDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHY 307
A ++A VGCP G+ + CL+ T P + + ++ + L +
Sbjct: 271 GMGEARRRATQLAHLVGCPPGGTGGNDTELVACLR-TRPAQVLVNHEWHV--LPQESVFR 327
Query: 308 VGFVPVIDGDFIPADPINLYANAAD---IDYIAGTNNMDGHIFASIDMPAINKGNKKVTE 364
FVPV+DGDF+ P L NA D + + G +G F P +K N+
Sbjct: 328 FSFVPVVDGDFLSDTPEAL-INAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNE---- 382
Query: 365 EDFYKLVSEFTITKGLR-GAKTTFDVYTES-------WAQDPSQENKKKTVVDFETDVLF 416
L+S G+R G D+ E+ W ++ + D D
Sbjct: 383 ----SLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNV 438
Query: 417 LVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGY 476
+ P +A R A+ A+ YAY+F H + +P W+G H +I+++FG P Y
Sbjct: 439 VCP--VAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNY 496
Query: 477 RPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRS 536
+++ ++ ++ YW NFA+TGDPN W PYT Y+ + + ++R
Sbjct: 497 TAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSL--DLRPLEVRRG 554
Query: 537 LRTNFLRYWTLTYLALPTVTD 557
LR +W L + TD
Sbjct: 555 LRAQACAFWNRFLPKLLSATD 575
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 261 bits (667), Expect = 2e-69
Identities = 178/542 (32%), Positives = 266/542 (49%), Gaps = 48/542 (8%)
Query: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKK 85
+ T+ G V G+N L + G +V F GIP+A P + PQ W A +
Sbjct: 34 IATKNGKVRGMN--LTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYAN 91
Query: 86 RCLQ-----------ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLM 134
C Q + + +T EDCLYLN+W+P + ++ V+IWIYGG F
Sbjct: 92 SCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKP---KNATVLIWIYGGGFQT 148
Query: 135 GSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLST-GDANLPGNYGLRDQHMA 193
G+ + ++YDG+ +A VIVV+ NYRVG LGFL+ G+ PGN GL DQ +A
Sbjct: 149 GTS------SLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLA 202
Query: 194 IAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQ 253
+ WV++NIAAFGG+P ++TLFGESAG ASVSL LSP + L RAI QSG +PW +
Sbjct: 203 LQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAV- 261
Query: 254 KNPLFWAK----KVAEKVGCPVGDAARMAQCLKVTDPRALTL--AYKVPLAGLEYPMLHY 307
L+ A+ +A+ GC + + +CL+ DP+ + L A+ VP Y
Sbjct: 262 -TSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVP-----YGTPLS 315
Query: 308 VGFVPVIDGDFIPADPINL--YANAADIDYIAGTNNMDGHIFASIDMPAINKGNKK-VTE 364
V F P +DGDF+ P L + G N +G F P +K N +T
Sbjct: 316 VNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITR 375
Query: 365 EDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIAL 424
++F + + F G ++ YT+ W D EN ++ + D D F+ P
Sbjct: 376 KEFQEGLKIFFPGVSEFGKESILFHYTD-WVDDQRPENYREALGDVVGDYNFICPALEFT 434
Query: 425 AQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVS 484
+ +A + Y F H S +P+W+G H +I++VFG P Y + +S
Sbjct: 435 KKFSEWGNNA--FFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILS 492
Query: 485 KAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRY 544
++++ W NFAK G+PN + T W + + YL + + S+ + LR R+
Sbjct: 493 RSIVKRWANFAKYGNPNETQNN-STSWPVFKSTEQKYLTLNTE--STRIMTKLRAQQCRF 549
Query: 545 WT 546
WT
Sbjct: 550 WT 551
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 236 bits (601), Expect = 8e-62
Identities = 193/574 (33%), Positives = 270/574 (47%), Gaps = 70/574 (12%)
Query: 9 LVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKA---L 65
L L + W S+ + V T G V G L V IF GIPFA P
Sbjct: 8 LATLSASAAWGHPSSPPV--VDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
Query: 66 ENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGD------------------EDCLYLN 107
PQP W A ++ C TQD G EDCLYLN
Sbjct: 66 TPPQPAEPWSFVKNATSYPPMC-----TQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
Query: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167
I+ P + +R LPVM+WI+GG ++G+ YDG +A NV+VVT YR
Sbjct: 121 IYTPADLTKKNR-LPVMVWIHGGGLMVGAAS--------TYDGLALAAHENVVVVTIQYR 171
Query: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227
+G GF STGD + GN+G DQ A+ WV+ NIA+FGG+P ++T+FGESAGG SVS+
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 228 LSPYNKGLIRRAISQSGVALSPWVIQK---NPLFWAKKVAEKVGCPVGDAARMAQCLK-V 283
LSP K L RAIS+SGVAL+ +++K PL A+++A GC +A M CL+
Sbjct: 232 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPL--AEQIAITAGCKTTTSAVMVHCLRQK 289
Query: 284 TDPRALTLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINLYA--NAADIDYIAG 338
T+ L K+ L+ P VIDG + P L A N + Y+ G
Sbjct: 290 TEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG 349
Query: 339 TNNMD-GHIFASIDMPAINKG--NKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWA 395
N + G + + +++G ++K +K I AK TE +
Sbjct: 350 INKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCI------AKELIPEATEKYL 403
Query: 396 QDPSQENKKKTV-VDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PS-RMPVYPK 452
KKK + +D DV+F VP+ I HR A TY Y F + PS + PK
Sbjct: 404 GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHR--DAGAPTYMYEFQYRPSFSSDMKPK 461
Query: 453 WVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWE 512
V DH D++ VFG PF G ++ +SK ++ +W NFA+ G+PN +P HW
Sbjct: 462 TVIGDHGDELFSVFGAPF-LKEGASEEEIRLSKMVMKFWANFARNGNPN--GEGLP-HWP 517
Query: 513 PYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546
Y + GYL+I ++ + L+ + +WT
Sbjct: 518 EY-NQKEGYLQIG---ANTQAAQKLKDKEVAFWT 547
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 234 bits (598), Expect = 2e-61
Identities = 176/564 (31%), Positives = 273/564 (48%), Gaps = 72/564 (12%)
Query: 31 TEGGFVEGVNKKLGLLGDSV--DIFKGIPFAAP---TKALENPQPHPGWQGTLKAKNFKK 85
T G+++G K++ +LG V ++F G+PFAAP + NPQP W +A ++
Sbjct: 35 TRLGWIQG--KQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPN 92
Query: 86 RCLQAT-----------ITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLM 134
CLQ + + EDCLYLNI+ P S+ LPV++W GGAF
Sbjct: 93 LCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK-LPVLVWFPGGAFKT 151
Query: 135 GSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAI 194
GS ++DG +A +V+VV YR+G GF +T D + PGN+ +DQ A+
Sbjct: 152 GSAS--------IFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAAL 203
Query: 195 AWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWV--- 251
+WV++NI FGGDP+++T+FGESAG SVS LSP KGL +AI +SGVA+ P++
Sbjct: 204 SWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAH 263
Query: 252 -IQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPR-ALTLAYKVPLAGLEYPMLHYVG 309
+K+ + VA G D+ + +CL+ + LTL+ K
Sbjct: 264 DYEKSEDL--QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK------------S 309
Query: 310 FVPVIDGDFIPADPINLYANAA--DIDYIAGTNNMD-GHIFASIDMPAINKGNKKVTEED 366
F V+DG F P +P++L + A I I G NN + G + + P I G+ K
Sbjct: 310 FTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALH 369
Query: 367 FYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQ 426
+ + + V E + S + +++D DV F+VP I
Sbjct: 370 LIQNILHIP-------PQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARY 422
Query: 427 HRANAKSAKTYAYLFSHPSRM--PVYPKWVGADHADDIQYVFGKPFATP-----TGYRPQ 479
HR A Y Y F H + P +V ADHAD++++VFG F G +
Sbjct: 423 HR--DAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEE 480
Query: 480 DRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRT 539
++ +S+ M+ YW FA+TG+PN D ++ W Y YL++ M S+ + L+
Sbjct: 481 EKLLSRKMMKYWATFARTGNPNGNDLSL---WPAYNLTEQ-YLQLDLNM---SLGQRLKE 533
Query: 540 NFLRYWTLTYLALPTVTDQEATPV 563
+ +WT T + + +D +P+
Sbjct: 534 PRVDFWTSTIPLILSASDMLHSPL 557
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 234 bits (596), Expect = 3e-61
Identities = 189/571 (33%), Positives = 268/571 (46%), Gaps = 63/571 (11%)
Query: 9 LVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKA---L 65
L L + W S+ + V T G V G L V IF GIPFA P
Sbjct: 8 LATLSASAAWGHPSSPPV--VDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
Query: 66 ENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGD------------------EDCLYLN 107
PQP W A ++ C TQD G EDCLYLN
Sbjct: 66 TPPQPAEPWSFVKNATSYPPMC-----TQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
Query: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167
I+ P + +R LPVM+WI+GG ++G+ YDG +A NV+VVT YR
Sbjct: 121 IYTPADLTKKNR-LPVMVWIHGGGLMVGAAS--------TYDGLALAAHENVVVVTIQYR 171
Query: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227
+G GF STGD + GN+G DQ A+ WV+ NIA+FGG+P ++T+FGESAGG SVS+
Sbjct: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
Query: 228 LSPYNKGLIRRAISQSGVALSPWVIQK---NPLFWAKKVAEKVGCPVGDAARMAQCLK-V 283
LSP K L RAIS+SGVAL+ +++K PL A+++A GC +A M CL+
Sbjct: 232 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPL--AEQIAITAGCKTTTSAVMVHCLRQK 289
Query: 284 TDPRALTLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINLYA--NAADIDYIAG 338
T+ L K+ L+ P VIDG + P L A N + Y+ G
Sbjct: 290 TEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG 349
Query: 339 TNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDP 398
N + + + + ++ ++ L+ + + AK TE +
Sbjct: 350 INKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCI--AKELIPEATEKYLGGT 407
Query: 399 SQENKKKTV-VDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PS-RMPVYPKWVG 455
KKK + +D DV+F VP+ I HR A TY Y F + PS + PK V
Sbjct: 408 DDTVKKKDLFLDLIADVMFGVPSVIVARNHR--DAGAPTYMYEFQYRPSFSSDMKPKTVI 465
Query: 456 ADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYT 515
DH D++ VFG PF G ++ +SK ++ +W NFA+ G+PN +P HW Y
Sbjct: 466 GDHGDELFSVFGAPF-LKEGASEEEIRLSKMVMKFWANFARNGNPN--GEGLP-HWPEY- 520
Query: 516 TENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546
+ GYL+I ++ + L+ + +WT
Sbjct: 521 NQKEGYLQIG---ANTQAAQKLKDKEVAFWT 548
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 233 bits (595), Expect = 4e-61
Identities = 189/571 (33%), Positives = 267/571 (46%), Gaps = 62/571 (10%)
Query: 9 LVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKA---L 65
L L + WA + V T G V G L V IF GIPFA P
Sbjct: 8 LATLSASAAWA-GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 66
Query: 66 ENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGD------------------EDCLYLN 107
PQP W A ++ C TQD G EDCLYLN
Sbjct: 67 TPPQPAEPWSFVKNATSYPPMC-----TQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 121
Query: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167
I+ P + +R LPVM+WI+GG ++G+ YDG +A NV+VVT YR
Sbjct: 122 IYTPADLTKKNR-LPVMVWIHGGGLMVGAAS--------TYDGLALAAHENVVVVTIQYR 172
Query: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227
+G GF STGD + GN+G DQ A+ WV+ NIA+FGG+P ++T+FGESAGG SVS+
Sbjct: 173 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 232
Query: 228 LSPYNKGLIRRAISQSGVALSPWVIQK---NPLFWAKKVAEKVGCPVGDAARMAQCLK-V 283
LSP K L RAIS+SGVAL+ +++K PL A+++A GC +A M CL+
Sbjct: 233 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPL--AEQIAITAGCKTTTSAVMVHCLRQK 290
Query: 284 TDPRALTLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINLYA--NAADIDYIAG 338
T+ L K+ L+ P VIDG + P L A N + Y+ G
Sbjct: 291 TEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG 350
Query: 339 TNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDP 398
N + + + + ++ ++ L+ + + AK TE +
Sbjct: 351 INKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCI--AKELIPEATEKYLGGT 408
Query: 399 SQENKKKTV-VDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PS-RMPVYPKWVG 455
KKK + +D DV+F VP+ I HR A TY Y F + PS + PK V
Sbjct: 409 DDTVKKKDLFLDLIADVMFGVPSVIVARNHR--DAGAPTYMYEFQYRPSFSSDMKPKTVI 466
Query: 456 ADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYT 515
DH D++ VFG PF G ++ +SK ++ +W NFA+ G+PN +P HW Y
Sbjct: 467 GDHGDELFSVFGAPF-LKEGASEEEIRLSKMVMKFWANFARNGNPN--GEGLP-HWPEY- 521
Query: 516 TENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546
+ GYL+I ++ + L+ + +WT
Sbjct: 522 NQKEGYLQIG---ANTQAAQKLKDKEVAFWT 549
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 230 bits (587), Expect = 3e-60
Identities = 182/577 (31%), Positives = 275/577 (47%), Gaps = 75/577 (12%)
Query: 10 VVLGLTC----CWAVASAAKLGA--VYTEGGFVEGVNKKLGLLGDS--VDIFKGIPFAAP 61
V++G+ C C A A+ ++ V T G V G +++G+ G V++F GIPFA P
Sbjct: 11 VLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRG--RQVGVKGTDRLVNVFLGIPFAQP 68
Query: 62 TKALEN---PQPHPGWQGTLKAKNFKKRCLQATITQDSTYG-----------DEDCLYLN 107
+ P P W+G A CLQ + +S+ EDCL LN
Sbjct: 69 PLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLN 128
Query: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167
++ P PVM+W++GGA + G+ YDG +A G+V+VVT YR
Sbjct: 129 VYSP-AEVPAGSGRPVMVWVHGGALITGAATS--------YDGSALAAYGDVVVVTVQYR 179
Query: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227
+G LGF STGD + PGN G D A+ WV+ NIA FGGD N +T+FG SAGG+ +S
Sbjct: 180 LGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLV 239
Query: 228 LSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPR 287
LSP GL RAI+QSGV +P +I +P A+K+A + C A M QCL+ +
Sbjct: 240 LSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGE 299
Query: 288 ALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAA--DIDYIAGTNNMDGH 345
L L+ K L YP+ +DG P P L + ++ G NN H
Sbjct: 300 ELVLSKK--LKNTIYPL--------TVDGTVFPKSPKELLKEKPFHSVPFLMGVNN---H 346
Query: 346 IFASIDMP---AINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYTESWAQDPSQ 400
F+ + +P + ++++ ED + + + + T D Y S +
Sbjct: 347 EFSWL-IPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGS---NSDA 402
Query: 401 ENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH--PSRMPVYPKWVGADH 458
+ K + +F DV VPT ++ +++ ++ S + Y F H S + P WV ADH
Sbjct: 403 QAKCQAFQEFMGDVFINVPT-VSFSRYLRDSGS-PVFFYEFQHRPSSFAKIKPAWVKADH 460
Query: 459 ADDIQYVFGKPFATPTGYR-------PQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHW 511
+ +VFG PF R +++ +S M+A WT+FA+TGDPN A+P W
Sbjct: 461 GAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPN--SKALPP-W 517
Query: 512 EPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLT 548
P + YLEI + + R ++++W+ T
Sbjct: 518 -PQFNQAEQYLEINPVPRAG---QKFREAWMQFWSET 550
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 216 bits (550), Expect = 6e-56
Identities = 164/517 (31%), Positives = 240/517 (46%), Gaps = 54/517 (10%)
Query: 50 VDIFKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTY-------- 98
V F GIPFA P P+P W G CLQ +S +
Sbjct: 119 VQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTF 178
Query: 99 ----GDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154
EDCLYL+I+ P + S +LPVM+WI+GGA + G LYDG +A
Sbjct: 179 PSDSMSEDCLYLSIYTPAHSHEGS-NLPVMVWIHGGALVFGMAS--------LYDGSMLA 229
Query: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214
NV+VV YR+G LGF STGD + GN+G DQ A+ WV++NIA FGG+P+ +T+F
Sbjct: 230 ALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIF 289
Query: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274
GESAGG SVS +SP ++GL AI +SGVAL P +I + + VA C D+
Sbjct: 290 GESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDS 349
Query: 275 ARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANA--AD 332
+ CL+ K + + P G V+DG F+P P L A+A
Sbjct: 350 EALVGCLRGKS--------KEEILAINKPFKMIPG---VVDGVFLPRHPQELLASADFQP 398
Query: 333 IDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTE 392
+ I G NN + M + + E L T+ L T D+ E
Sbjct: 399 VPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL---LMLPPTFGDLLRE 455
Query: 393 SWAQDPSQ-ENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PSRMP-V 449
+ D + + + D +F++P AL A Y Y F H PS + +
Sbjct: 456 EYIGDNGDPQTLQAQFQEMMADSMFVIP---ALQVAHFQCSRAPVYFYEFQHQPSWLKNI 512
Query: 450 YPKWVGADHADDIQYVFGKPF-ATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVP 508
P + ADH D++ +VF F + ++ +S+ M+ YW NFA+ G+PN +P
Sbjct: 513 RPPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPN--GEGLP 570
Query: 509 THWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYW 545
HW P + YL++ + ++ R+L+ + L++W
Sbjct: 571 -HW-PLFDQEEQYLQLNLQ---PAVGRALKAHRLQFW 602
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 204 bits (519), Expect = 2e-52
Identities = 160/516 (31%), Positives = 233/516 (45%), Gaps = 68/516 (13%)
Query: 50 VDIFKGIPFAAPTKA---LENPQPHPGWQGTLKAKNFKKRCLQATITQDSTY-------- 98
V F GIPFA P P+P W G CLQ +S +
Sbjct: 119 VQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTF 178
Query: 99 ----GDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIA 154
EDCLYL+I+ P + S +LPVM+WI+GGA + G LYDG +A
Sbjct: 179 PSDSMSEDCLYLSIYTPAHSHEGS-NLPVMVWIHGGALVFGMAS--------LYDGSMLA 229
Query: 155 TRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLF 214
NV+VV YR+G LGF STGD + GN+G DQ A+ WV++NIA FGG+P+ +T+F
Sbjct: 230 ALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIF 289
Query: 215 GESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDA 274
GESAGG SVS +SP ++GL AI +SGVAL P +I + + VA C D+
Sbjct: 290 GESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDS 349
Query: 275 ARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANA--AD 332
+ CL+ K + + P G V+DG F+P P L A+A
Sbjct: 350 EALVGCLRGKS--------KEEILAINKPFKMIPG---VVDGVFLPRHPQELLASADFQP 398
Query: 333 IDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTE 392
+ I G NN + M + + E L T+ L T D+ E
Sbjct: 399 VPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL---LMLPPTFGDLLRE 455
Query: 393 SWAQDPSQ-ENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PSRMP-V 449
+ D + + + D +F++P AL A Y Y F H PS + +
Sbjct: 456 EYIGDNGDPQTLQAQFQEMMADSMFVIP---ALQVAHFQCSRAPVYFYEFQHQPSWLKNI 512
Query: 450 YPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPT 509
P + ADH + ++ +S+ M+ YW NFA+ G+PN +P
Sbjct: 513 RPPHMKADHVK---------------FTEEEEQLSRKMMKYWANFARNGNPN--GEGLP- 554
Query: 510 HWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYW 545
HW P + YL++ + ++ R+L+ + L++W
Sbjct: 555 HW-PLFDQEEQYLQLNLQ---PAVGRALKAHRLQFW 586
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 200 bits (508), Expect = 5e-51
Identities = 160/557 (28%), Positives = 251/557 (45%), Gaps = 108/557 (19%)
Query: 31 TEGGFVEGVNKKLGLLGDSV--DIFKGIPFAAP---TKALENPQPHPGWQGTLKAKNFKK 85
T G+++G K++ +LG V ++F G+PFAAP + NPQP W +A ++
Sbjct: 35 TRLGWIQG--KQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPN 92
Query: 86 RCLQAT-----------ITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLM 134
CLQ + + EDCLYLNI+ P S+ LPV++W GGAF
Sbjct: 93 LCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK-LPVLVWFPGGAFKT 151
Query: 135 GSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAI 194
GS ++DG +A +V+VV YR+G GF +T D + PGN+ +DQ A+
Sbjct: 152 GSAS--------IFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAAL 203
Query: 195 AWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWV--- 251
+WV++NI FGGDP+++T+FGESAG SVS LSP KGL +AI +SGVA+ P++
Sbjct: 204 SWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAH 263
Query: 252 -IQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPR-ALTLAYKVPLAGLEYPMLHYVG 309
+K+ + VA G D+ + +CL+ + LTL+ K
Sbjct: 264 DYEKSEDL--QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK------------S 309
Query: 310 FVPVIDGDFIPADPINLYANAA--DIDYIAGTNNMD-GHIFASIDMPAINKGNKKVTEED 366
F V+DG F P +P++L + A I I G NN + G + + P I G+ K
Sbjct: 310 FTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALH 369
Query: 367 FYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQ 426
+ + + V E + S + +++D DV F+VP I
Sbjct: 370 LIQNILHIP-------PQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARY 422
Query: 427 HRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKA 486
HR A +++ +S+
Sbjct: 423 HREGATE---------------------------------------------EEKLLSRK 437
Query: 487 MIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546
M+ YW FA+TG+PN D ++ W Y YL++ M S+ + L+ + +WT
Sbjct: 438 MMKYWATFARTGNPNGNDLSL---WPAYNLTEQ-YLQLDLNM---SLGQRLKEPRVDFWT 490
Query: 547 LTYLALPTVTDQEATPV 563
T + + +D +P+
Sbjct: 491 STIPLILSASDMLHSPL 507
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 199 bits (506), Expect = 8e-51
Identities = 126/359 (35%), Positives = 185/359 (51%), Gaps = 43/359 (11%)
Query: 17 CWAVA----SAAKLGAVYTEG-------GFVEGVNKKLGLLGDSVDIFKGIPFAAPTKAL 65
CW++ + LGA++T+ G ++G +G + +F G+PF+ P +
Sbjct: 6 CWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT--PIQVFLGVPFSRPPLGI 63
Query: 66 EN---PQPHPGWQGTLKAKNFKKRCLQATITQDSTYG------------DEDCLYLNIWV 110
P+P W+G A + CLQ + Q ++ EDCLYLN++
Sbjct: 64 LRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYA 123
Query: 111 PQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGP 170
P R LPVM+W GGAF++G+ Y+G ++A R V++V +R+G
Sbjct: 124 P-ARAPGDPQLPVMVWFPGGAFIVGAASS--------YEGSDLAAREKVVLVFLQHRLGI 174
Query: 171 LGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSP 230
GFLST D++ GN+GL DQ A+ WV+ NIAAFGGDP N+TLFG+SAG S+S +SP
Sbjct: 175 FGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSP 234
Query: 231 YNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLK-VTDPRAL 289
GL RAISQSG AL I NPL AKKVA GC + CL+ ++ + +
Sbjct: 235 LASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVM 294
Query: 290 TLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINL--YANAADIDYIAGTNNMD 343
++ K+ L + P PV+DG IP DP+ L + + Y+ G NN++
Sbjct: 295 RVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLE 353
Score = 35.8 bits (81), Expect = 0.15
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 9/72 (12%)
Query: 479 QDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYT-TENSGYLEITKKMGSSSMKRSL 537
+++ +S M+ YW NFA+TG+PN G+ W Y E L+ T ++G L
Sbjct: 417 KEKALSLQMMKYWANFARTGNPNDGNLPC---WPRYNKDEKYLQLDFTTRVG-----MKL 468
Query: 538 RTNFLRYWTLTY 549
+ + +W Y
Sbjct: 469 KEKKMAFWMSLY 480
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 157 bits (398), Expect = 3e-38
Identities = 157/556 (28%), Positives = 246/556 (44%), Gaps = 82/556 (14%)
Query: 42 KLGLLGDSVDIFKGIPFAAPTKALENPQ-PHP-GWQGTLKAKNFKKRCLQ-ATITQDSTY 98
++G VD F G+P+AAP A Q P P W G+ A + C Q T T S
Sbjct: 2217 QVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPG 2276
Query: 99 GDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGS-GHGANFLNNYLYDGEEIATRG 157
EDCLYLN+++PQ V+ + V+++ + S G A DG +A G
Sbjct: 2277 VSEDCLYLNVFIPQN---VAPNASVLVFFHNTMDREESEGWPA-------IDGSFLAAVG 2326
Query: 158 NVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGES 217
N+IVVT +YRVG GFLS+G + GN+GL DQ A+ WV+ +I FGGDP ++L +
Sbjct: 2327 NLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADR 2386
Query: 218 AGG--ASVSLQTLSPYNKGLIRRAISQSGVALSPWVI--QKNPLFWAKKVAEKVGCPVGD 273
G AS+ L T N L RRA+ G ALSP + + A +A++V CP+
Sbjct: 2387 GGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSS 2446
Query: 274 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANA--A 331
+ + CL+ L A + L + P HY G PVIDG F+ P +
Sbjct: 2447 SQEVVSCLRQKPANVLNDA-QTKLLAVSGP-FHYWG--PVIDGHFLREPPARALKRSLWV 2502
Query: 332 DIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTF---- 387
++D + G++ DG IN+ K V +F ++G +KT F
Sbjct: 2503 EVDLLIGSSQDDG---------LINRA----------KAVKQFEESRGRTSSKTAFYQAL 2543
Query: 388 ---------DVYTESWAQ-DPSQENKKKTVVDFE------TDVLFLVPTEIALAQHRANA 431
D E+ A S E+ F T F++ I +A A A
Sbjct: 2544 QNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMAS--AWA 2601
Query: 432 KSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPF--ATPTGYRPQDRTVSKAMIA 489
K A+ +++ P + D+Q+ G PF A + +++++S ++
Sbjct: 2602 KRARGNVFMYHAPENY----GHGSLELLADVQFALGLPFYPAYEGQFSLEEKSLSLKIMQ 2657
Query: 490 YWTNFAKTGDPNMG---DSAVPTH---WEPYTTENSG--YLEITKKMGSSSMKRSLRTNF 541
Y+++F ++G+PN VPT W + G Y E ++ + + ++ L+
Sbjct: 2658 YFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLPN---RQGLKKAD 2714
Query: 542 LRYWTLTYLALPTVTD 557
+W+ +L T D
Sbjct: 2715 CSFWSKYISSLKTSAD 2730
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 155 bits (391), Expect = 2e-37
Identities = 77/192 (40%), Positives = 92/192 (47%)
Query: 550 LALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPP 609
L LP + P PP + P PP + PP +G PP PP +G PP PP
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPP 991
Query: 610 TGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSG 669
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP +G
Sbjct: 992 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
Query: 670 APPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVP 729
PP PP AG PP PP +G PP PP +G PP P + P PP G PP P
Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
Query: 730 PTGDSEAAPVPP 741
P + P PP
Sbjct: 1112 PLPGAGIPPPPP 1123
Score = 154 bits (389), Expect = 3e-37
Identities = 75/180 (41%), Positives = 88/180 (48%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 977 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1036
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP AG
Sbjct: 1037 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP PP G PP PP +G PP P + P PP +G PP PP P PP
Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156
Score = 154 bits (389), Expect = 3e-37
Identities = 75/180 (41%), Positives = 88/180 (48%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
+G PP PP +G PP PP +G PP PP +G PP PP G PP PP AG
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP PP +G PP PP +G PP P P PP +G PP PP + P PP
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Score = 154 bits (388), Expect = 4e-37
Identities = 74/178 (41%), Positives = 88/178 (49%)
Query: 564 PPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 623
PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
Query: 624 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPP 683
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP AG PP
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087
Query: 684 VPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP +G PP PP G PP P + P PP +G PP PP + P PP
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145
Score = 154 bits (388), Expect = 4e-37
Identities = 74/180 (41%), Positives = 88/180 (48%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 988 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP G
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1107
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP PP +G PP PP +G PP P + P PP G PP PP + P PP
Sbjct: 1108 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167
Score = 153 bits (386), Expect = 6e-37
Identities = 76/183 (41%), Positives = 90/183 (49%), Gaps = 1/183 (0%)
Query: 560 ATPVPPTGDSEATPVPPT-GDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV 618
A P PP P+PP + P PP +G PP PP +G PP PP +G PP
Sbjct: 952 AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011
Query: 619 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 678
PP +G PP PP +G PP PP +G PP PP +G PP PP +G PP PP
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
Query: 679 AGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAP 738
AG PP PP +G PP PP +G PP P P PP +G PP PP + P
Sbjct: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP 1131
Query: 739 VPP 741
PP
Sbjct: 1132 PPP 1134
Score = 153 bits (386), Expect = 6e-37
Identities = 75/180 (41%), Positives = 87/180 (48%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
+G PP PP +G PP PP +G PP PP G PP PP +G PP PP AG
Sbjct: 1070 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGI 1129
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP PP +G PP PP G PP P + P PP +G PP PP P PP
Sbjct: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189
Score = 152 bits (385), Expect = 8e-37
Identities = 74/186 (39%), Positives = 91/186 (48%)
Query: 556 TDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA 615
T+ P PP + P PP + P+PP +G PP PP + PP PP +G
Sbjct: 905 TEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI 964
Query: 616 PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPP 675
P PP +G PP PP +G PP PP +G PP PP +G PP PP +G PP PP
Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
Query: 676 TGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSE 735
AG PP PP +G PP PP +G PP P + P PP +G PP PP +
Sbjct: 1025 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 736 AAPVPP 741
P PP
Sbjct: 1085 IPPPPP 1090
Score = 152 bits (383), Expect = 1e-36
Identities = 73/180 (40%), Positives = 89/180 (49%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P+PP + P PP + PP PP +G P PP +G PP PP
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
+G PP PP +G PP PP +G PP PP +G PP PP +G PP PP AG
Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP PP +G PP PP +G PP P + P PP +G PP PP + P PP
Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101
Score = 152 bits (383), Expect = 1e-36
Identities = 75/180 (41%), Positives = 86/180 (47%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
+G PP PP +G PP PP G PP PP +G PP PP +G PP PP AG
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP PP G PP PP +G PP P + P PP G PP PP P PP
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
Score = 151 bits (382), Expect = 2e-36
Identities = 74/180 (41%), Positives = 86/180 (47%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
+G PP PP G PP PP +G PP PP +G PP PP +G PP PP G
Sbjct: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGI 1151
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
PP PP +G PP PP +G PP P P PP G PP PP + P PP
Sbjct: 1152 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
Score = 149 bits (376), Expect = 9e-36
Identities = 74/179 (41%), Positives = 84/179 (46%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP +G PP PP
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
G PP PP +G PP PP +G PP PP +G PP PP G PP PP AG
Sbjct: 1103 PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI 1162
Query: 682 PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVP 740
PP PP +G PP PP G PP P P PP +G PP PP P P
Sbjct: 1163 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP 1221
Score = 144 bits (364), Expect = 2e-34
Identities = 75/195 (38%), Positives = 94/195 (48%), Gaps = 4/195 (2%)
Query: 550 LALPTVTDQEATPVPPT---GDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPP 606
+ +PT+ A P PP + P PP + P PP +G P+PP +G PP
Sbjct: 886 MTVPTLPST-AIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPP 944
Query: 607 VPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 666
PP + PP PP +G P PP +G PP PP +G PP PP +G PP PP
Sbjct: 945 PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1004
Query: 667 DSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAP 726
+G PP PP AG PP PP +G PP PP +G PP P + P PP +G P
Sbjct: 1005 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1064
Query: 727 PVPPTGDSEAAPVPP 741
P PP + P PP
Sbjct: 1065 PPPPLPGAGIPPPPP 1079
Score = 142 bits (357), Expect = 1e-33
Identities = 76/181 (41%), Positives = 86/181 (47%), Gaps = 8/181 (4%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP +G PP PP G PP PP
Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT-GDAG 680
+G PP PP +G PP PP +G PP PP G PP PP +G PP PP G AG
Sbjct: 1114 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPG-AG 1172
Query: 681 PPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVP 740
PP PP G PP PP G PP P + P PP G PP P A P+P
Sbjct: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP------APPLP 1226
Query: 741 P 741
P
Sbjct: 1227 P 1227
Score = 135 bits (341), Expect = 1e-31
Identities = 77/200 (38%), Positives = 92/200 (46%), Gaps = 7/200 (3%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP + P PP +G PP PP G PP PP +G PP PP
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPP---TGD 678
+G PP PP +G PP PP G PP PP +G PP PP +G PP PP G
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1184
Query: 679 AGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTG--DSETAPVPPTGDSGAPPVPPTGDSEA 736
PPP+P G PP+P G PP+ G + P+PP G +G PP PP
Sbjct: 1185 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG-TGIPP-PPLLPVSG 1242
Query: 737 APVPPTDDSKEAQMPAVIRF 756
P+ P S P V F
Sbjct: 1243 PPLLPQVGSSTLPTPQVCGF 1262
Score = 135 bits (339), Expect = 2e-31
Identities = 74/197 (37%), Positives = 89/197 (45%), Gaps = 7/197 (3%)
Query: 552 LPTVTDQEATP----VPPTGDSEATPVPPTGDSETAPVPPT---GDSGAPPVPPTGDSGA 604
LP + P VPP PT S P PP + PP PP +G
Sbjct: 861 LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI 920
Query: 605 PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPP 664
PP PP +G P+PP +G PP PP + PP PP +G P PP +G PP PP
Sbjct: 921 PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Query: 665 TGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSG 724
+G PP PP AG PP PP +G PP PP +G PP P + P PP +G
Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
Query: 725 APPVPPTGDSEAAPVPP 741
PP PP + P PP
Sbjct: 1041 IPPPPPLPGAGIPPPPP 1057
Score = 132 bits (333), Expect = 9e-31
Identities = 72/182 (39%), Positives = 81/182 (44%), Gaps = 14/182 (7%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP + P PP P PP +G PP PP +G PP PP +G PP PP
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP 681
G PP PP +G PP PP +G PP PP G PP PP G PP PP AG
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGI 1206
Query: 682 PPVPPTGDSG-----APPVPPTGDS---------GAPPVTPTGDSETAPVPPTGDSGAPP 727
PP PP G APP+PP G PP+ P S T P P PP
Sbjct: 1207 PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266
Query: 728 VP 729
+P
Sbjct: 1267 LP 1268
Score = 107 bits (266), Expect = 5e-23
Identities = 62/168 (36%), Positives = 78/168 (46%), Gaps = 3/168 (1%)
Query: 575 PPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 634
PP +E++ P PP PP P +P T PP+ T + PP PP
Sbjct: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT-EMLPPPPPPLPG 917
Query: 635 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT-GDAGPPPVPPTGDSGAP 693
+G PP PP +G P+PP +G PP PP + PP PP G AG P PP +G P
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-AGIPLPPPLPGAGIP 976
Query: 694 PVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
P PP +G PP P + P PP +G PP PP + P PP
Sbjct: 977 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
Score = 78.6 bits (192), Expect = 2e-14
Identities = 66/263 (25%), Positives = 87/263 (33%), Gaps = 89/263 (33%)
Query: 568 DSEATPVPPTGDSETAPVPPT-GDSGAPPVPPTGDSG----------------------- 603
++++ PT + +PP G G PP PP +SG
Sbjct: 740 EAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLD 799
Query: 604 ---------APPVPPT-------GDSGA------------------------------PP 617
PP PP+ G G+ PP
Sbjct: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859
Query: 618 VPPTGDSGA---------PPVPPTGDSGAPPVPPTG----------DSGAPPVPPTGDSG 658
P +S + PP PP P +P T + PP PP +G
Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919
Query: 659 APPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVP 718
PP PP +G P+PP AG PP PP + PP PP +G P P + P P
Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP 979
Query: 719 PTGDSGAPPVPPTGDSEAAPVPP 741
P +G PP PP + P PP
Sbjct: 980 PLPGAGIPPPPPLPGAGIPPPPP 1002
Score = 49.3 bits (116), Expect = 1e-05
Identities = 36/101 (35%), Positives = 43/101 (42%), Gaps = 11/101 (10%)
Query: 552 LPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTG 611
LP V P+P G P+P G P+P G PP P APP+PP G
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG---IPPAP------APPLPPPG 1229
Query: 612 DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 652
+G PP P SG P +P G S P P PP+P
Sbjct: 1230 -TGIPPPPLLPVSGPPLLPQVG-SSTLPTPQVCGFLPPPLP 1268
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 126 bits (317), Expect = 7e-29
Identities = 95/313 (30%), Positives = 150/313 (47%), Gaps = 47/313 (15%)
Query: 129 GGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLR 188
GGAF GS ++DG +A +++VV YR+G GF +T D + PGN+ +
Sbjct: 20 GGAFETGSAS--------IFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFK 71
Query: 189 DQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALS 248
DQ A++WV++NI FGGDP+++T+FGES G SVS LSP +GL +A+ +SGVA+
Sbjct: 72 DQVAALSWVQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAII 131
Query: 249 PWV----IQKNPLFWAKKVAEKVGCPVGDAARMAQCLKV-TDPRALTLAYKVPLAGLEYP 303
++ +K+ + VA+ G D+ +CL+ + LTL+ K
Sbjct: 132 LYLKAHDYEKSEDL--QVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK------- 182
Query: 304 MLHYVGFVPVIDGDFIPADPINLYANAA--DIDYIAGTNNMD-GHIFASIDMPAINKGNK 360
F V+DG F P +P++L + A I I G NN + G + P I G+
Sbjct: 183 -----AFTQVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSN 237
Query: 361 K-----VTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVL 415
K +T+ + L + + G E + S + +++D DV
Sbjct: 238 KSLALCLTQNILHILPNYLHLVAG------------EYFHDKHSLTEIRDSLLDLLGDVF 285
Query: 416 FLVPTEIALAQHR 428
F++P I HR
Sbjct: 286 FVIPKLITARYHR 298
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 126 bits (317), Expect = 7e-29
Identities = 95/313 (30%), Positives = 150/313 (47%), Gaps = 47/313 (15%)
Query: 129 GGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLR 188
GGAF GS ++DG +A +++VV YR+G GF +T D + PGN+ +
Sbjct: 20 GGAFETGSAS--------IFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFK 71
Query: 189 DQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALS 248
DQ A++WV++NI FGGDP+++T+FGES G SVS LSP +GL +A+ +SGVA+
Sbjct: 72 DQVAALSWVQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAII 131
Query: 249 PWV----IQKNPLFWAKKVAEKVGCPVGDAARMAQCLKV-TDPRALTLAYKVPLAGLEYP 303
++ +K+ + VA+ G D+ +CL+ + LTL+ K
Sbjct: 132 LYLKAHDYEKSEDL--QVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK------- 182
Query: 304 MLHYVGFVPVIDGDFIPADPINLYANAA--DIDYIAGTNNMD-GHIFASIDMPAINKGNK 360
F V+DG F P +P++L + A I I G NN + G + P I G+
Sbjct: 183 -----AFTQVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSN 237
Query: 361 K-----VTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVL 415
K +T+ + L + + G E + S + +++D DV
Sbjct: 238 KSLALCLTQNILHILPNYLHLVAG------------EYFHDKHSLTEIRDSLLDLLGDVF 285
Query: 416 FLVPTEIALAQHR 428
F++P I HR
Sbjct: 286 FVIPKLITAQYHR 298
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 116 bits (290), Expect = 9e-26
Identities = 84/199 (42%), Positives = 96/199 (48%), Gaps = 20/199 (10%)
Query: 560 ATPVPPTGDSEATPVPPT----GDSETA--PVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 613
A VPP+ S A PVPP GDS T P P GDS PP PP PP+P
Sbjct: 560 AITVPPSVPSRA-PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 618
Query: 614 GAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP---PTGDSGAPPVPPTGDSGA 670
+PP P G + +PP P +GD+ PP PP + P P P G + PP P G +
Sbjct: 619 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 678
Query: 671 PPVPPT--GDAGPPPVPPT--GDSGAPPVPPT--GDSGAPPVTP-TGDSETAPVPPTGDS 723
PP PP G AG PP PP G++G PP PP G G PP P G P PP
Sbjct: 679 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP--GM 736
Query: 724 GAPPVPPTG-DSEAAPVPP 741
G PP PP G AAPV P
Sbjct: 737 GMPPPPPFGFGVPAAPVLP 755
Score = 100 bits (249), Expect = 5e-21
Identities = 68/171 (39%), Positives = 79/171 (46%), Gaps = 24/171 (14%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVP-----------PTGDSGAPPVPPTGDSGAPPVPPT 610
P P GDS P PP P+P P G + +PP P +GD+ PP PP
Sbjct: 589 PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL 648
Query: 611 GDSGAPPVP---PTGDSGAPPVPPTGDSGAPPVPP--TGDSGAPPVPP--TGDSGAPPVP 663
+ P P P G + PP P G + PP PP G +G PP PP G++G PP P
Sbjct: 649 PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP 708
Query: 664 P--TGDSGAPPVPP-TGDAGPPPVPPTGDSGAPPVPPTG-DSGAPPVTPTG 710
P G G PP PP G G PP PP G PP PP G A PV P G
Sbjct: 709 PPLPGGPGIPPPPPFPGGPGIPPPPP--GMGMPPPPPFGFGVPAAPVLPFG 757
Score = 90.9 bits (224), Expect = 4e-18
Identities = 65/165 (39%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 591 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA--PPVPPTGDSGAPPVPPTGDSGA 648
+ A VPP+ S AP VPP APP+P GDSG PP P GDS PP PP
Sbjct: 558 AAAITVPPSVPSRAP-VPP-----APPLP--GDSGTIIPPPPAPGDSTTPPPPPPPPPPP 609
Query: 649 PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPT--GDSGAPPV 706
PP+P +PP P G + +PP P +GDA PP PP + P P + G + PP
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 669
Query: 707 TPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMP 751
P S P PP PP S P PP EA MP
Sbjct: 670 PPLPGSARIPPPP---------PPLPGSAGIPPPPPPLPGEAGMP 705
Score = 70.5 bits (171), Expect = 6e-12
Identities = 50/129 (38%), Positives = 57/129 (44%), Gaps = 18/129 (13%)
Query: 553 PTVTDQEATPVPPTGDSEATPVP---PTGDSETAPVPPTGDSGAPPVPPT--GDSGAPPV 607
P D P PP + P P P G + P P G + PP PP G +G PP
Sbjct: 635 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 694
Query: 608 PPT--GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 665
PP G++G PP PP G P +PP PP P G G PP PP G PP PP
Sbjct: 695 PPPLPGEAGMPPPPPP-LPGGPGIPP-----PPPFP--GGPGIPPPPP--GMGMPPPPPF 744
Query: 666 GDSGAPPVP 674
G G P P
Sbjct: 745 G-FGVPAAP 752
Score = 60.5 bits (145), Expect = 6e-09
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 646 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP--PPVPPTGDSGAPPVPPTGDSGA 703
+ A VPP+ S AP VPP APP+P GD+G PP P GDS PP PP
Sbjct: 558 AAAITVPPSVPSRAP-VPP-----APPLP--GDSGTIIPPPPAPGDSTTPPPPPPPPPPP 609
Query: 704 PPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPA 752
PP+ + P P G + +PP P +GD+ P PP + P+
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 116 bits (290), Expect = 9e-26
Identities = 84/199 (42%), Positives = 96/199 (48%), Gaps = 20/199 (10%)
Query: 560 ATPVPPTGDSEATPVPPT----GDSETA--PVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 613
A VPP+ S A PVPP GDS T P P GDS PP PP PP+P
Sbjct: 569 AITVPPSVPSRA-PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 627
Query: 614 GAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP---PTGDSGAPPVPPTGDSGA 670
+PP P G + +PP P +GD+ PP PP + P P P G + PP P G +
Sbjct: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687
Query: 671 PPVPPT--GDAGPPPVPPT--GDSGAPPVPPT--GDSGAPPVTP-TGDSETAPVPPTGDS 723
PP PP G AG PP PP G++G PP PP G G PP P G P PP
Sbjct: 688 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP--GM 745
Query: 724 GAPPVPPTG-DSEAAPVPP 741
G PP PP G AAPV P
Sbjct: 746 GMPPPPPFGFGVPAAPVLP 764
Score = 100 bits (249), Expect = 5e-21
Identities = 68/171 (39%), Positives = 79/171 (46%), Gaps = 24/171 (14%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVP-----------PTGDSGAPPVPPTGDSGAPPVPPT 610
P P GDS P PP P+P P G + +PP P +GD+ PP PP
Sbjct: 598 PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL 657
Query: 611 GDSGAPPVP---PTGDSGAPPVPPTGDSGAPPVPP--TGDSGAPPVPP--TGDSGAPPVP 663
+ P P P G + PP P G + PP PP G +G PP PP G++G PP P
Sbjct: 658 PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP 717
Query: 664 P--TGDSGAPPVPP-TGDAGPPPVPPTGDSGAPPVPPTG-DSGAPPVTPTG 710
P G G PP PP G G PP PP G PP PP G A PV P G
Sbjct: 718 PPLPGGPGIPPPPPFPGGPGIPPPPP--GMGMPPPPPFGFGVPAAPVLPFG 766
Score = 90.9 bits (224), Expect = 4e-18
Identities = 65/165 (39%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 591 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA--PPVPPTGDSGAPPVPPTGDSGA 648
+ A VPP+ S AP VPP APP+P GDSG PP P GDS PP PP
Sbjct: 567 AAAITVPPSVPSRAP-VPP-----APPLP--GDSGTIIPPPPAPGDSTTPPPPPPPPPPP 618
Query: 649 PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPT--GDSGAPPV 706
PP+P +PP P G + +PP P +GDA PP PP + P P + G + PP
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 678
Query: 707 TPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMP 751
P S P PP PP S P PP EA MP
Sbjct: 679 PPLPGSARIPPPP---------PPLPGSAGIPPPPPPLPGEAGMP 714
Score = 70.5 bits (171), Expect = 6e-12
Identities = 50/129 (38%), Positives = 57/129 (44%), Gaps = 18/129 (13%)
Query: 553 PTVTDQEATPVPPTGDSEATPVP---PTGDSETAPVPPTGDSGAPPVPPT--GDSGAPPV 607
P D P PP + P P P G + P P G + PP PP G +G PP
Sbjct: 644 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 703
Query: 608 PPT--GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 665
PP G++G PP PP G P +PP PP P G G PP PP G PP PP
Sbjct: 704 PPPLPGEAGMPPPPPP-LPGGPGIPP-----PPPFP--GGPGIPPPPP--GMGMPPPPPF 753
Query: 666 GDSGAPPVP 674
G G P P
Sbjct: 754 G-FGVPAAP 761
Score = 60.5 bits (145), Expect = 6e-09
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 646 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP--PPVPPTGDSGAPPVPPTGDSGA 703
+ A VPP+ S AP VPP APP+P GD+G PP P GDS PP PP
Sbjct: 567 AAAITVPPSVPSRAP-VPP-----APPLP--GDSGTIIPPPPAPGDSTTPPPPPPPPPPP 618
Query: 704 PPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPA 752
PP+ + P P G + +PP P +GD+ P PP + P+
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 97.1 bits (240), Expect = 6e-20
Identities = 82/282 (29%), Positives = 110/282 (39%), Gaps = 43/282 (15%)
Query: 496 KTGDPNMGD---SAVPTHWEPYTTENSG--YLEITKKMGSSSMKRSLRTNFLRYWTLTYL 550
K +PN G+ + T E + G ++E +K+G+S +L + +
Sbjct: 182 KKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTL------VYQNGSI 235
Query: 551 ALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPP-----------TGDSGAPPVPPT 599
D + P PP DS ++P P + P P +G +G
Sbjct: 236 GCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVV 295
Query: 600 GDSGAPPVPPTGDSGAPPVPPTGDSG--APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 657
S PP PP G +PP P G + APP PP G PP PP G+P PP
Sbjct: 296 SPSHPPPAPPLG---SPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPP---- 348
Query: 658 GAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGD--SGAPPVTPTGDSETA 715
PP PP+ PP P PPP PP D P PP GAPP P
Sbjct: 349 --PPSPPS----FPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGP 402
Query: 716 PVPP-TGDSGAPPVPPTGDSEAAP---VPPTDDSKEAQMPAV 753
P PP TG G P +PP P +P D++ + A+
Sbjct: 403 PPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAI 444
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 95.9 bits (237), Expect = 1e-19
Identities = 69/194 (35%), Positives = 81/194 (41%), Gaps = 30/194 (15%)
Query: 569 SEATPVPPT-----GDSETAPVPPTGD------SGAPPVPPTGDSGAPPVPPTGDSGAPP 617
S P+PPT D P PP G+ PP PP + PPVP T P
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK--PPVPST------P 298
Query: 618 VPPTGDSGAPPVPPTGDSGAPPVPPT--GDSGAPPVPPTG---DSGAPPVPPTGDSGAPP 672
P PP PP G PP+PP+ G+ P +P S PP+P G SG P
Sbjct: 299 RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 673 VPPTGDAGPPPVPPTGDSGA-PPVPPTGDSG----APPVTPTGDSETAPVPPTGDSGAPP 727
PP+ PP P G SG PP PP +G A P TP S + P PP
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPR-SGPRPP 417
Query: 728 VPPTGDSEAAPVPP 741
+PP S AP PP
Sbjct: 418 LPPDRPSAGAPPPP 431
Score = 87.0 bits (214), Expect = 6e-17
Identities = 77/236 (32%), Positives = 90/236 (38%), Gaps = 59/236 (25%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTG---DSGAPPVPPTG--------DSGAPPVP-- 608
PVP G P P + P P G DS PPVP T + G+PPVP
Sbjct: 151 PVPSPGHRSGPPEPQR-NRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG 209
Query: 609 PTGDSGAPPVPP-TGDSGA---------------------PPVPPT-----GDSGAPPVP 641
P S P PP G+ G PP+PPT D PP P
Sbjct: 210 PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 642 PTGD------SGAPPVPPTGDSGAPPVPPTGDSGA-----PPVPPTGDAGPPPVPP--TG 688
P G+ PP PP + PPVP T A PP PP GPPP+PP +G
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNK--PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 689 DSGAPPVPPTG---DSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
+ P +P S PP+ G S P PP+ P P G S P PP
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383
Score = 86.3 bits (212), Expect = 1e-16
Identities = 78/245 (31%), Positives = 95/245 (38%), Gaps = 69/245 (28%)
Query: 566 TGDSEATPVPPTGDSETA-PVPPTGDSGAPPVPPTGDSGAPPVP-------PTGDSGAPP 617
+G S +PP G S +A P P G PVP G PP P P D G+ P
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 618 --VPPTGDS------------GAPPVP--PTGDSGAPPVPP-TGDSGA------------ 648
+PP S G+PPVP P S P PP G+ G
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
Query: 649 ---------PPVPPT-----GDSGAPPVPPTGD------SGAPPVPPTGDAGPPPVP--- 685
PP+PPT D PP PP G+ PP PP + PPVP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN--KPPVPSTP 298
Query: 686 -PTGDSGAPPVPPTGDSGAPPVTP---TGDSETAPVPPTG---DSGAPPVPPTGDSEAAP 738
P+ S APP PP PP P +G+ ET +P S PP+P G S P
Sbjct: 299 RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 739 VPPTD 743
PP++
Sbjct: 359 PPPSE 363
Score = 84.7 bits (208), Expect = 3e-16
Identities = 82/249 (32%), Positives = 95/249 (38%), Gaps = 74/249 (29%)
Query: 563 VPPTGDS-EATPVPPTGDSETAPVPPTGDSGAPPVP-------PTGDSGA------PPVP 608
+PP G S A P P PVP G PP P P D G+ PPVP
Sbjct: 129 LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188
Query: 609 PTG--------DSGAPPVP--PTGDSGAPPVPP-TGDSGA-------------------- 637
T + G+PPVP P S P PP G+ G
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 638 -PPVPPT-----GDSGAPPVPPTGD------SGAPPVPPTGDSGAPPVPPT------GDA 679
PP+PPT D PP PP G+ PP PP + PPVP T A
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK--PPVPSTPRPSASSQA 306
Query: 680 GPPPVPPTGDSGAPPVPP--TGDSGAPPVTPTG---DSETAPVPPTGDSGAPPVPPTGDS 734
PPP PP G PP+PP +G+ P + S T P+P G SG P PP S
Sbjct: 307 PPPP-PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP---S 362
Query: 735 EAAPVPPTD 743
E P P D
Sbjct: 363 ERPPPPVRD 371
Score = 82.0 bits (201), Expect = 2e-15
Identities = 60/175 (34%), Positives = 77/175 (44%), Gaps = 30/175 (17%)
Query: 557 DQEATPVPPTGDS-----EATPVPPTGDSE----TAPVPPTGDSGAPPVPPTGDSGAPPV 607
D+ P PP G+ EA P PP +++ + P P PP PP G PP+
Sbjct: 262 DKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL 321
Query: 608 PPT--GDSGAPPVPPTG---DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA-PP 661
PP+ G+ P +P S PP+P G SG P PP+ P P G SG PP
Sbjct: 322 PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 662 VPPTGDSGA--------PPVPPTGD-----AGP-PPVPPTGDS-GAPPVPPTGDS 701
PP +G+ P +P +GP PP+PP S GAPP PP S
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTS 436
Score = 61.2 bits (147), Expect = 3e-09
Identities = 56/188 (29%), Positives = 68/188 (36%), Gaps = 22/188 (11%)
Query: 589 GDSGAPPVPPTGDSGAPPVPPT-------GDSGAPPVPPTGDS-GAPPVPPTGDSGAPPV 640
G G P + +G P + T G S P +PP G S A P P G PV
Sbjct: 93 GGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 641 PPTGDSGAPPVPPTGDSGAPPVPPTG---DSGAPPVPPTG--------DAGPPPVPPTGD 689
P G PP P PP P G DS PPVP T + G PPVP
Sbjct: 153 PSPGHRSGPPEPQRNRM-PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211
Query: 690 SGAP-PVPPTGDSGAPPVTPTGDSETAPVPPTGD-SGAPPVPPTGDSEAAPVPPTDDSKE 747
+P P PP G +P+ + S PP+PPT PP
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271
Query: 748 AQMPAVIR 755
P++ R
Sbjct: 272 GNRPSIHR 279
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 95.9 bits (237), Expect = 1e-19
Identities = 69/194 (35%), Positives = 81/194 (41%), Gaps = 30/194 (15%)
Query: 569 SEATPVPPT-----GDSETAPVPPTGD------SGAPPVPPTGDSGAPPVPPTGDSGAPP 617
S P+PPT D P PP G+ PP PP + PPVP T P
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK--PPVPST------P 298
Query: 618 VPPTGDSGAPPVPPTGDSGAPPVPPT--GDSGAPPVPPTG---DSGAPPVPPTGDSGAPP 672
P PP PP G PP+PP+ G+ P +P S PP+P G SG P
Sbjct: 299 RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 673 VPPTGDAGPPPVPPTGDSGA-PPVPPTGDSG----APPVTPTGDSETAPVPPTGDSGAPP 727
PP+ PP P G SG PP PP +G A P TP S + P PP
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPR-SGPRPP 417
Query: 728 VPPTGDSEAAPVPP 741
+PP S AP PP
Sbjct: 418 LPPDRPSAGAPPPP 431
Score = 87.0 bits (214), Expect = 6e-17
Identities = 77/236 (32%), Positives = 90/236 (38%), Gaps = 59/236 (25%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTG---DSGAPPVPPTG--------DSGAPPVP-- 608
PVP G P P + P P G DS PPVP T + G+PPVP
Sbjct: 151 PVPSPGHRSGPPEPQR-NRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG 209
Query: 609 PTGDSGAPPVPP-TGDSGA---------------------PPVPPT-----GDSGAPPVP 641
P S P PP G+ G PP+PPT D PP P
Sbjct: 210 PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 642 PTGD------SGAPPVPPTGDSGAPPVPPTGDSGA-----PPVPPTGDAGPPPVPP--TG 688
P G+ PP PP + PPVP T A PP PP GPPP+PP +G
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNK--PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 689 DSGAPPVPPTG---DSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741
+ P +P S PP+ G S P PP+ P P G S P PP
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383
Score = 86.3 bits (212), Expect = 1e-16
Identities = 78/245 (31%), Positives = 95/245 (38%), Gaps = 69/245 (28%)
Query: 566 TGDSEATPVPPTGDSETA-PVPPTGDSGAPPVPPTGDSGAPPVP-------PTGDSGAPP 617
+G S +PP G S +A P P G PVP G PP P P D G+ P
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 618 --VPPTGDS------------GAPPVP--PTGDSGAPPVPP-TGDSGA------------ 648
+PP S G+PPVP P S P PP G+ G
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240
Query: 649 ---------PPVPPT-----GDSGAPPVPPTGD------SGAPPVPPTGDAGPPPVP--- 685
PP+PPT D PP PP G+ PP PP + PPVP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN--KPPVPSTP 298
Query: 686 -PTGDSGAPPVPPTGDSGAPPVTP---TGDSETAPVPPTG---DSGAPPVPPTGDSEAAP 738
P+ S APP PP PP P +G+ ET +P S PP+P G S P
Sbjct: 299 RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 739 VPPTD 743
PP++
Sbjct: 359 PPPSE 363
Score = 84.7 bits (208), Expect = 3e-16
Identities = 82/249 (32%), Positives = 95/249 (38%), Gaps = 74/249 (29%)
Query: 563 VPPTGDS-EATPVPPTGDSETAPVPPTGDSGAPPVP-------PTGDSGA------PPVP 608
+PP G S A P P PVP G PP P P D G+ PPVP
Sbjct: 129 LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188
Query: 609 PTG--------DSGAPPVP--PTGDSGAPPVPP-TGDSGA-------------------- 637
T + G+PPVP P S P PP G+ G
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 638 -PPVPPT-----GDSGAPPVPPTGD------SGAPPVPPTGDSGAPPVPPT------GDA 679
PP+PPT D PP PP G+ PP PP + PPVP T A
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK--PPVPSTPRPSASSQA 306
Query: 680 GPPPVPPTGDSGAPPVPP--TGDSGAPPVTPTG---DSETAPVPPTGDSGAPPVPPTGDS 734
PPP PP G PP+PP +G+ P + S T P+P G SG P PP S
Sbjct: 307 PPPP-PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP---S 362
Query: 735 EAAPVPPTD 743
E P P D
Sbjct: 363 ERPPPPVRD 371
Score = 82.0 bits (201), Expect = 2e-15
Identities = 60/175 (34%), Positives = 77/175 (44%), Gaps = 30/175 (17%)
Query: 557 DQEATPVPPTGDS-----EATPVPPTGDSE----TAPVPPTGDSGAPPVPPTGDSGAPPV 607
D+ P PP G+ EA P PP +++ + P P PP PP G PP+
Sbjct: 262 DKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL 321
Query: 608 PPT--GDSGAPPVPPTG---DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA-PP 661
PP+ G+ P +P S PP+P G SG P PP+ P P G SG PP
Sbjct: 322 PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 662 VPPTGDSGA--------PPVPPTGD-----AGP-PPVPPTGDS-GAPPVPPTGDS 701
PP +G+ P +P +GP PP+PP S GAPP PP S
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTS 436
Score = 61.2 bits (147), Expect = 3e-09
Identities = 56/188 (29%), Positives = 68/188 (36%), Gaps = 22/188 (11%)
Query: 589 GDSGAPPVPPTGDSGAPPVPPT-------GDSGAPPVPPTGDS-GAPPVPPTGDSGAPPV 640
G G P + +G P + T G S P +PP G S A P P G PV
Sbjct: 93 GGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 641 PPTGDSGAPPVPPTGDSGAPPVPPTG---DSGAPPVPPTG--------DAGPPPVPPTGD 689
P G PP P PP P G DS PPVP T + G PPVP
Sbjct: 153 PSPGHRSGPPEPQRNRM-PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR 211
Query: 690 SGAP-PVPPTGDSGAPPVTPTGDSETAPVPPTGD-SGAPPVPPTGDSEAAPVPPTDDSKE 747
+P P PP G +P+ + S PP+PPT PP
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271
Query: 748 AQMPAVIR 755
P++ R
Sbjct: 272 GNRPSIHR 279
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 94.0 bits (232), Expect = 5e-19
Identities = 76/241 (31%), Positives = 96/241 (39%), Gaps = 41/241 (17%)
Query: 546 TLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPP--VPPTGDSG 603
T T PT T T P T + T +PPT T P PPT + PP P+ +
Sbjct: 1489 TTTTTPPPTTTPSPPTTTPITPPASTTTLPPT----TTPSPPTTTTTTPPPTTTPSPPTT 1544
Query: 604 APPVPPTGDSGAPPV-----PPTGDSGAPPV----PPTGDSGAPPV-----PPTGDSGAP 649
P PPT + PP PPT + PP PPT + +PP PP + +P
Sbjct: 1545 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP 1604
Query: 650 PV-----PPTGDSGAPPV-----PPTGDSGAPPV-----PPTGDAGPPPV----PPTGDS 690
P PP + +PP PPT + PP PPT PPP PPT +
Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664
Query: 691 GAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQM 750
+PP+ T + P TP+ T P PPT + P P T S T S
Sbjct: 1665 PSPPITTT-TTPPPTTTPSSPITTTPSPPT-TTMTTPSPTTTPSSPITTTTTPSSTTTPS 1722
Query: 751 P 751
P
Sbjct: 1723 P 1723
Score = 89.4 bits (220), Expect = 1e-17
Identities = 77/243 (31%), Positives = 95/243 (39%), Gaps = 62/243 (25%)
Query: 550 LALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPP--VPPTGDSGAPPV 607
++ T TP PPT TP PPT T P PPT + PP P+ + P
Sbjct: 1458 ISTTTTPPPTTTPSPPT----TTPSPPT----TTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509
Query: 608 PPTGDSGAPPV----PPTGDSGAPPV-----PPTGDSGAPP-----VPPTGDSGAPPV-- 651
PP + PP PPT + PP PPT PP +PPT PP
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1569
Query: 652 ---PPTGDSGAPPVPPTGDSGAPPV------PPTGDAGPP------------PVPPTGDS 690
PPT P PPT + +PP PPT PP P PPT
Sbjct: 1570 TTPPPT----TTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625
Query: 691 GAPP-----VPPTGDSGAPP-VTPTGDSETAPVPPTGDSGAPPV-----PPTGDSEAAPV 739
PP +PPT PP T T T P PPT + +PP+ PP + ++P+
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPI 1685
Query: 740 PPT 742
T
Sbjct: 1686 TTT 1688
Score = 87.4 bits (215), Expect = 4e-17
Identities = 72/232 (31%), Positives = 88/232 (37%), Gaps = 39/232 (16%)
Query: 546 TLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDS-----ETAPVPPTGDSGAP-----P 595
T T PT T T T TP PP + T P PP + P P
Sbjct: 1411 TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP 1470
Query: 596 VPPTGDSGAP---PVPPTGDSGAPP--VPPTGDSGAPPVPPTGDSGAPPV----PPTGDS 646
PPT P P PPT + PP P+ + P PP + PP PPT +
Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTT 1530
Query: 647 GAPP--VPPTGDSGAPPVPPTGDSGAPPV-----PPTGDAGPPPV----PPTGDSGAPP- 694
PP P+ + P PPT + PP PPT PPP PPT + +PP
Sbjct: 1531 TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT 1590
Query: 695 ----VPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPT 742
PP + +PP T T T P P T S P T + +PPT
Sbjct: 1591 ITTTTPPPTTTPSPPTTTT----TTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638
Score = 87.0 bits (214), Expect = 6e-17
Identities = 71/230 (30%), Positives = 92/230 (40%), Gaps = 41/230 (17%)
Query: 553 PTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPV-----PPTGDSGAPPV 607
P+ T +PPT TP PPT T PP + +PP+ PP + +PP+
Sbjct: 1406 PSPPPTSTTTLPPT----TTPSPPT---TTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 608 -----PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPP--VPPTGDSGAPPVPPTGDSGAP 660
PP + +PP P PPT + PP P+ + P PP + P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 661 PV----PPTGDSGAPPVPPTGDAGPPPV----PPTGDSGAPPV-----PPTGDSGAPP-V 706
P PPT + PP PT PP PPT + PP PPT + PP
Sbjct: 1519 PTTTPSPPTTTTTTPP--PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576
Query: 707 TPTGDSETAPVPPTGDSGAP-----PVPPTGDSEAAPVPPTDDSKEAQMP 751
TP+ + T P PPT + P P PPT + P P T S P
Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPTTTPSPPT-TTTTTPPPTTTPSPPTTTP 1625
Score = 83.2 bits (204), Expect = 8e-16
Identities = 73/227 (32%), Positives = 84/227 (37%), Gaps = 43/227 (18%)
Query: 546 TLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPV-----PPTG 600
T T PT T T P T + T +PPT T P PP + PP PPT
Sbjct: 1528 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT----TTPSPPPTTTTTPPPTTTPSPPTT 1583
Query: 601 DSGAPPV------PPTGDSGAPPVPPTGDSGAPPV-----PPTGDSGAPP-----VPPTG 644
+ +PP PPT P PPT + PP PPT PP +PPT
Sbjct: 1584 TTPSPPTITTTTPPPT----TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639
Query: 645 DSGAPPV-----PPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTG 699
PP PPT P PPT + +PP+ T PP P+ P PPT
Sbjct: 1640 TPSPPPTTTTTPPPT----TTPSPPTTTTPSPPITTT-TTPPPTTTPSSPITTTPSPPTT 1694
Query: 700 DSGAPPVTPTGDS----ETAPVPPTGDSGAPPVPPTGDSEAAPVPPT 742
P T T S T P T S P T P PPT
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741
Score = 80.5 bits (197), Expect = 5e-15
Identities = 68/218 (31%), Positives = 81/218 (37%), Gaps = 14/218 (6%)
Query: 546 TLTYLALPTVTDQEATPVP-PTGDSEATPVPPTGDSETAPVP-PTGDSGAPPVPPTGDSG 603
T T P T TP P PTG T P T + P P PTG P T +
Sbjct: 4032 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4091
Query: 604 APPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAP 660
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 4092 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4151
Query: 661 PVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGAPPVP-PTGDSGAPPVTPTGDSETAPVP 718
P T + P P PTG P P T + P P PTG PP + TAP+
Sbjct: 4152 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT----HTSTAPIA 4207
Query: 719 PTGDSGAPP---VPPTGDSEAAPVPPTDDSKEAQMPAV 753
S PP P T S ++P+ + PA+
Sbjct: 4208 ELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 4245
Score = 80.1 bits (196), Expect = 7e-15
Identities = 70/224 (31%), Positives = 87/224 (38%), Gaps = 41/224 (18%)
Query: 546 TLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPV-----PPTG 600
TL P+ T PPT TP PPT T P PPT + PP PPT
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPT----TTPSPPT---TTTPSPPTITTTTPPPTTTPSPPTT 1607
Query: 601 DSGAPP--VPPTGDSGAPPVPPTGDSGAPPV-----PPTGDSGAPPV----PPTGDSGAP 649
+ PP P+ + P PPT + PP PPT + PP PPT + +P
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667
Query: 650 PV------PPTGDSGAP----PVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTG 699
P+ PPT +P P PPT + P P T + P T S P PP
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPT-TTMTTPSPTTTPSSPITTTTTPSSTTTPSPP-- 1724
Query: 700 DSGAPPVTPTGDSETAPVPPTGD-SGAPPVPPTGDSEAAPVPPT 742
P T T P PPT + PP + P+PP+
Sbjct: 1725 ----PTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764
Score = 78.2 bits (191), Expect = 3e-14
Identities = 67/215 (31%), Positives = 76/215 (35%), Gaps = 9/215 (4%)
Query: 546 TLTYLALPTVTDQEATPVP-PTGDSEATPVPPTGDSETAPVP-PTGDSGAPPVPPTGDSG 603
T T P T TP P PTG T P T + P P PTG P T +
Sbjct: 3940 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3999
Query: 604 APPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAP 660
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 4000 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4059
Query: 661 PVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTP-TGDSETAPVP 718
P T + P P PTG P P T + P P + P TP T + P P
Sbjct: 4060 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4119
Query: 719 -PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQMP 751
PTG P T + P P PT P
Sbjct: 4120 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154
Score = 75.5 bits (184), Expect = 2e-13
Identities = 66/214 (30%), Positives = 80/214 (37%), Gaps = 57/214 (26%)
Query: 582 TAPVPPTGDSGAPP-----VPPTGDSGAP----PVPPTGDSGAPPV-----PPTGDSGAP 627
T P PPT PP +PPT P PP + +PP+ PP + +P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 628 PV-----PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP-----PVPPTGDSGAPP----- 672
P+ PP + +PP P PPT + P P PPT PP
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 673 VPPTGDAGPP------------PVPPTGDSGAPP-----VPPTGDSGAPP-VTPTGDSET 714
+PPT PP P PPT PP +PPT PP T T T
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576
Query: 715 APVPPTGDSGAPPV------PPTGDSEAAPVPPT 742
P PPT + +PP PPT P PPT
Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPT----TTPSPPT 1606
Score = 75.5 bits (184), Expect = 2e-13
Identities = 89/309 (28%), Positives = 112/309 (36%), Gaps = 47/309 (15%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 4002 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 4050
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVP-PTGDSETAPVPP 587
+ + T T+T PT T Q T P T + TP P PTG P
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4109
Query: 588 TGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTG 644
T + P P PTG P T + P P PTG P T + P P PTG
Sbjct: 4110 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4169
Query: 645 DSGAPPVPPTGDSGAPPVP-PTGDSGAP-------PVPPTGDAGPPP---VPPTGDSGAP 693
P T + P P PTG P P+ + PPP P T S +
Sbjct: 4170 TQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSS 4229
Query: 694 P----------VPPTGD--SGAPPVTPTGDSETAP----VPPTGDSGAPPVPP----TGD 733
P +PP + S APP TPT + T+ PP + +PP P T
Sbjct: 4230 PLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTG 4289
Query: 734 SEAAPVPPT 742
S +AP P T
Sbjct: 4290 SSSAPTPST 4298
Score = 72.8 bits (177), Expect = 1e-12
Identities = 72/247 (29%), Positives = 85/247 (34%), Gaps = 9/247 (3%)
Query: 513 PYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEAT 572
P TT + +T + + T T+T PT T Q T P T + T
Sbjct: 1896 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVT 1954
Query: 573 PVP-PTGDSETAPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPV 629
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2014
Query: 630 PPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDAGPPPVP-P 686
P T + P P PTG P T + P P PTG P T P P P
Sbjct: 2015 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2074
Query: 687 TGDSGAPPVPPTGDSGAPPV-TPTGDSETAPVPPTGDSGAPPVP-PTGDSEAAPVPPTDD 744
TG P T + P TPTG P T + P P PTG P T
Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2134
Query: 745 SKEAQMP 751
+ P
Sbjct: 2135 TTVTPTP 2141
Score = 71.2 bits (173), Expect = 3e-12
Identities = 65/224 (29%), Positives = 76/224 (33%), Gaps = 18/224 (8%)
Query: 546 TLTYLALPTVTDQEATPV----------PPTGDSEATPVPPTGDSETAPVP-PTGDSGAP 594
T+T T TP+ PTG T P T + P P PTG
Sbjct: 1884 TMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1943
Query: 595 PVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP 652
P T + P P PTG P T + P P PTG P T + P P
Sbjct: 1944 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2003
Query: 653 -PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTP-T 709
PTG P T + P P PTG P P T + P P + P TP T
Sbjct: 2004 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063
Query: 710 GDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQMP 751
+ P P PTG P T + P P PT P
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107
Score = 70.5 bits (171), Expect = 6e-12
Identities = 58/200 (29%), Positives = 73/200 (36%), Gaps = 27/200 (13%)
Query: 553 PTVTDQEATPVPPTGDSEATPVPPTGDSETAPV-PPTGDSGAPPV-----PPTGDSGAPP 606
PT T T T TP PPT T P+ PPT + PP PPT + PP
Sbjct: 1598 PTTTPSPPTTTTTTPPPTTTPSPPT----TTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653
Query: 607 V----PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV 662
PPT + +PP+ T + P P+ P PPT P T S
Sbjct: 1654 TTTPSPPTTTTPSPPITTT-TTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Query: 663 PPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGD 722
+ P PPT P P + P P T + PP T + T P+PP+
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSP------TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS-- 1764
Query: 723 SGAPPVPPTGDSEAAPVPPT 742
PPT + P T
Sbjct: 1765 ----ITPPTFSPFSTTTPTT 1780
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 1909 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 1957
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2018 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2077
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2078 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2137
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2138 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197
Query: 750 MP 751
P
Sbjct: 2198 TP 2199
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2001 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2049
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2229
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2230 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289
Query: 750 MP 751
P
Sbjct: 2290 TP 2291
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2093 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2141
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2142 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2261
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2262 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2321
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381
Query: 750 MP 751
P
Sbjct: 2382 TP 2383
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2185 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2233
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2413
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2414 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473
Query: 750 MP 751
P
Sbjct: 2474 TP 2475
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2277 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2325
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2326 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2506 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565
Query: 750 MP 751
P
Sbjct: 2566 TP 2567
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2369 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2417
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2537
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2538 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2597
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2598 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657
Query: 750 MP 751
P
Sbjct: 2658 TP 2659
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2461 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2509
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2510 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2629
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2630 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749
Query: 750 MP 751
P
Sbjct: 2750 TP 2751
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2553 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2601
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2602 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2781
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2782 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841
Query: 750 MP 751
P
Sbjct: 2842 TP 2843
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2645 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2693
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933
Query: 750 MP 751
P
Sbjct: 2934 TP 2935
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2737 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2785
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2786 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025
Query: 750 MP 751
P
Sbjct: 3026 TP 3027
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2829 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2877
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2878 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3057
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117
Query: 750 MP 751
P
Sbjct: 3118 TP 3119
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 2921 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 2969
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 2970 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3149
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209
Query: 750 MP 751
P
Sbjct: 3210 TP 3211
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3013 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3061
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3062 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301
Query: 750 MP 751
P
Sbjct: 3302 TP 3303
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3105 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3153
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3333
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393
Query: 750 MP 751
P
Sbjct: 3394 TP 3395
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3197 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3245
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3246 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3425
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485
Query: 750 MP 751
P
Sbjct: 3486 TP 3487
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3289 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3337
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3338 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577
Query: 750 MP 751
P
Sbjct: 3578 TP 3579
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3381 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3429
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3430 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3609
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669
Query: 750 MP 751
P
Sbjct: 3670 TP 3671
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3473 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3521
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3522 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3701
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3702 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3761
Query: 750 MP 751
P
Sbjct: 3762 TP 3763
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3565 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3613
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3614 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3734 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3793
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3794 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3853
Query: 750 MP 751
P
Sbjct: 3854 TP 3855
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3657 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3705
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3706 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3885
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3886 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3945
Query: 750 MP 751
P
Sbjct: 3946 TP 3947
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3749 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3797
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3798 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3857
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3858 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3917
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 3918 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3977
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 3978 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4037
Query: 750 MP 751
P
Sbjct: 4038 TP 4039
Score = 69.3 bits (168), Expect = 1e-11
Identities = 82/302 (27%), Positives = 100/302 (33%), Gaps = 30/302 (9%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 3841 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 3889
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEAT-PVPPTGDSEATPVPPTGDSET----- 582
+ + T T+T PT T T P+ T TP P + T
Sbjct: 3890 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949
Query: 583 -----APVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGD 634
P P PTG P T + P P PTG P T + P P PTG
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009
Query: 635 SGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDAGPPPVPPTGDSGA 692
P T + P P PTG P T + P P PTG P P T +
Sbjct: 4010 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4069
Query: 693 PPVPPTGDSGAPPVTP-TGDSETAPVP-PTGDSGAPPVPPTGDSEAAPVP-PTDDSKEAQ 749
P P + P TP T + P P PTG P T + P P PT
Sbjct: 4070 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129
Query: 750 MP 751
P
Sbjct: 4130 TP 4131
Score = 65.5 bits (158), Expect = 2e-10
Identities = 67/210 (31%), Positives = 79/210 (37%), Gaps = 29/210 (13%)
Query: 546 TLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPV-----PPTG 600
T T PT T T P T + T +PPT T P PP + PP PPT
Sbjct: 1607 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT----TTPSPPPTTTTTPPPTTTPSPPTT 1662
Query: 601 DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP 660
+ +PP+ T + P P+ P PPT + P P T S T S
Sbjct: 1663 TTPSPPITTT-TTPPPTTTPSSPITTTPSPPT-TTMTTPSPTTTPSSPITTTTTPSSTTT 1720
Query: 661 PVPPTGDSGAPPVPPTGDAGPP-----PVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETA 715
P PP P PT PP +PPT S P S PP T + S T
Sbjct: 1721 PSPPPTTMTTP--SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP-TFSPFSTTT 1777
Query: 716 PVPP-------TG--DSGAPPV-PPTGDSE 735
P P TG DSG P P GD+E
Sbjct: 1778 PTTPCVPLCNWTGWLDSGKPNFHKPGGDTE 1807
Score = 62.8 bits (151), Expect = 1e-09
Identities = 58/196 (29%), Positives = 67/196 (34%), Gaps = 11/196 (5%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP-P 620
P T + P PPT T P+ T + P PTG P T + P P P
Sbjct: 1882 PTTMTTTTTENPTPPT----TTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1936
Query: 621 TGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVP-PTGDSGAPPVPPTGD 678
TG P T + P P PTG P T + P P PTG P T
Sbjct: 1937 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1996
Query: 679 AGPPPVP-PTGDSGAPPVPPTGDSGAPPV-TPTGDSETAPVPPTGDSGAPPVP-PTGDSE 735
P P PTG P T + P TPTG P T + P P PTG
Sbjct: 1997 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2056
Query: 736 AAPVPPTDDSKEAQMP 751
P T + P
Sbjct: 2057 PTTTPITTTTTVTPTP 2072
Score = 57.0 bits (136), Expect = 6e-08
Identities = 74/263 (28%), Positives = 94/263 (35%), Gaps = 34/263 (12%)
Query: 469 PFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKM 528
P TPTG +T + I T T P + T P TT + +T
Sbjct: 4071 PTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTT----VTPTP 4119
Query: 529 GSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVP-PTGDSETAPVPP 587
+ + T T+T PT T Q T P T + TP P PTG P
Sbjct: 4120 TPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4178
Query: 588 TGDSGAPPVP-PTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 646
T + P P PTG PP T S A P+ S PP T + P +S
Sbjct: 4179 TTTTTVTPTPTPTGTQTGPP---THTSTA-PIAELTTSNPPPESSTPQTSRSTSSPLTES 4234
Query: 647 GA--PPVPPTGD--SGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPP----- 697
+PP + S APP PT P T G PP + +PP P
Sbjct: 4235 TTLLSTLPPAIEMTSTAPPSTPT-------APTTTSGGHTLSPPPSTTTSPPGTPTRGTT 4287
Query: 698 TGDSGAPPVTPTGDSETAPVPPT 720
TG S AP + + T+ PT
Sbjct: 4288 TGSSSAPTPSTVQTTTTSAWTPT 4310
Score = 56.2 bits (134), Expect = 1e-07
Identities = 41/127 (32%), Positives = 51/127 (40%), Gaps = 21/127 (16%)
Query: 639 PVPPTGDSGAPP-----VPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPP----PVPPTGD 689
P PPT PP +PPT P PPT + P PPT PP PP
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPT----TTPSPPTTTTTTP--PPTTTPSPPITTTTTPPPTT 1452
Query: 690 SGAPPV-----PPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDD 744
+ +PP+ PP + +PP T T P PPT + PP P T S P T
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP-PTTTPSPPTTTPITPP 1511
Query: 745 SKEAQMP 751
+ +P
Sbjct: 1512 ASTTTLP 1518
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 92.0 bits (227), Expect = 2e-18
Identities = 59/154 (38%), Positives = 65/154 (42%), Gaps = 17/154 (11%)
Query: 604 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 663
APP PP G PP PP + PP PP GAPP PP S AP P PP P
Sbjct: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPP---SRAPTAAP------PPPP 326
Query: 664 PTGDSGAPPVPPTGDAGPPPVP--PTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTG 721
P+ S A P PP PPP P P+ PP PP G PV P P PP
Sbjct: 327 PSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPP------PPPPPP 380
Query: 722 DSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIR 755
PP PP S+ PT +A + IR
Sbjct: 381 PPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIR 414
Score = 90.9 bits (224), Expect = 4e-18
Identities = 52/126 (41%), Positives = 58/126 (46%), Gaps = 9/126 (7%)
Query: 593 APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA--PPVPPTGDSGAPP 650
APP PP G PP PP + PP PP GAPP PP+ A PP PP+ S A P
Sbjct: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335
Query: 651 VPPTGDSGAPP---VPPTGDSGAPPVPPT----GDAGPPPVPPTGDSGAPPVPPTGDSGA 703
PP PP +P + SG PP PP+ G PPP PP PP PP S
Sbjct: 336 PPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDG 395
Query: 704 PPVTPT 709
PT
Sbjct: 396 DHQVPT 401
Score = 89.7 bits (221), Expect = 9e-18
Identities = 51/128 (39%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 581 ETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA--PPVPPTGDSGAP 638
+ P PP G PP PP + PP PP GAPP PP+ A PP PP+ S A
Sbjct: 275 QAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV 334
Query: 639 PVPPTGDSGAPPVP--PTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVP 696
P PP PP P P+ PP PP G PV P PPP PP G P +P
Sbjct: 335 PPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPP--PPPPPPPGPPPPPGLP 392
Query: 697 PTGDSGAP 704
GD P
Sbjct: 393 SDGDHQVP 400
Score = 87.0 bits (214), Expect = 6e-17
Identities = 53/136 (38%), Positives = 61/136 (44%), Gaps = 10/136 (7%)
Query: 584 PVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT--GDSGAPPVPPTGDSGAPPVP 641
P PP+ PP PP +SG PP PP GAPP PP+ + PP PP+ S A P P
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPP-PPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337
Query: 642 PTGDSGAPPVP--PTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTG 699
P PP P P+ PP PP G PV P PPP PP G PP P
Sbjct: 338 PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP-----PPPPPPPPPPGPPPPPGLP 392
Query: 700 DSGAPPVTPTGDSETA 715
G V T ++ A
Sbjct: 393 SDGDHQVPTTAGNKAA 408
Score = 86.3 bits (212), Expect = 1e-16
Identities = 53/135 (39%), Positives = 60/135 (44%), Gaps = 10/135 (7%)
Query: 573 PVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPT--GDSGAPPVPPTGDSGAPPVP 630
P PP+ P PP +SG PP PP GAPP PP+ + PP PP+ S A P P
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPP-PPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337
Query: 631 PTGDSGAPPVP--PTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTG 688
P PP P P+ PP PP G PV P PP PP GPPP P
Sbjct: 338 PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP-----PPPPPPPPPPGPPPPPGLP 392
Query: 689 DSGAPPVPPTGDSGA 703
G VP T + A
Sbjct: 393 SDGDHQVPTTAGNKA 407
Score = 66.6 bits (161), Expect = 8e-11
Identities = 47/141 (33%), Positives = 51/141 (36%), Gaps = 31/141 (21%)
Query: 553 PTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 612
P P PP A P PP+ AP PP PP+ S A P PP
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP---------PPPPPSRPSVAVPPPPPNR 341
Query: 613 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPP 672
PP PP P+ PP PP G PV APP PP PP
Sbjct: 342 MYPPP---------PPALPSSAPSGPPPPPPSVLGVGPV-------APPPPP------PP 379
Query: 673 VPPTGDAGPPPVPPTGDSGAP 693
PP G PP +P GD P
Sbjct: 380 PPPPGPPPPPGLPSDGDHQVP 400
Score = 51.2 bits (121), Expect = 3e-06
Identities = 36/98 (36%), Positives = 39/98 (39%), Gaps = 14/98 (14%)
Query: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 621
P PP+ S A P PP P PP S AP SG PP PP+ P PP
Sbjct: 324 PPPPSRPSVAVPPPPPNRMYPPP-PPALPSSAP-------SGPPPPPPSVLGVGPVAPP- 374
Query: 622 GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA 659
PP PP G PP P G VP T + A
Sbjct: 375 -----PPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKA 407
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.135 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,241,051
Number of Sequences: 37866
Number of extensions: 2880451
Number of successful extensions: 66514
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 504
Number of HSP's successfully gapped in prelim test: 1229
Number of HSP's that attempted gapping in prelim test: 15990
Number of HSP's gapped (non-prelim): 15380
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.