Search of human proteins with 148224884

Search of human proteins with 148224884

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148224884 protein tyrosine phosphatase, mitochondrial 1
isoform 1 [Homo sapiens]
         (201 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isofo...   403   e-113
gi|221218988 protein tyrosine phosphatase, mitochondrial 1 isofo...   120   8e-28
gi|239582767 slingshot homolog 3 [Homo sapiens]                        50   2e-06
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             48   6e-06
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               46   2e-05
gi|9910432 dual specificity phosphatase 22 [Homo sapiens]              45   3e-05
gi|51491914 dual specificity phosphatase and pro isomerase domai...    42   3e-04
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              42   3e-04
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    42   3e-04
gi|56786144 dual specificity phosphatase 23 [Homo sapiens]             42   4e-04
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]             41   6e-04
gi|66346728 laforin isoform b [Homo sapiens]                           41   8e-04
gi|11321613 laforin isoform a [Homo sapiens]                           41   8e-04
gi|75750526 dual specificity phosphatase 28 [Homo sapiens]             41   8e-04
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     40   0.001
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]    40   0.001
gi|13128968 dual specificity phosphatase 26 [Homo sapiens]             40   0.001
gi|4758206 dual specificity phosphatase 2 [Homo sapiens]               40   0.001
gi|134142828 RNA guanylyltransferase and 5'-phosphatase [Homo sa...    39   0.003
gi|37674210 slingshot 2 [Homo sapiens]                                 39   0.003
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi...    39   0.003
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi...    39   0.003
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    39   0.003
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              38   0.007
gi|239047414 slingshot 1 isoform 1 [Homo sapiens]                      37   0.009
gi|239047498 slingshot 1 isoform 3 [Homo sapiens]                      37   0.009
gi|239047441 slingshot 1 isoform 2 [Homo sapiens]                      37   0.009
gi|6005956 dual specificity phosphatase 12 [Homo sapiens]              37   0.009
gi|122937243 dual specificity phosphatase 27 [Homo sapiens]            37   0.015
gi|30089952 protein tyrosine phosphatase domain containing 1 pro...    37   0.015

>gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isoform
           1 [Homo sapiens]
          Length = 201

 Score =  403 bits (1035), Expect = e-113
 Identities = 201/201 (100%), Positives = 201/201 (100%)

Query: 1   MAATALLEAGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQLV 60
           MAATALLEAGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQLV
Sbjct: 1   MAATALLEAGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQLV 60

Query: 61  QDENVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALK 120
           QDENVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALK
Sbjct: 61  QDENVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALK 120

Query: 121 YQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLK 180
           YQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLK
Sbjct: 121 YQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLK 180

Query: 181 EFHKQITARATKDGTFVISKT 201
           EFHKQITARATKDGTFVISKT
Sbjct: 181 EFHKQITARATKDGTFVISKT 201


>gi|221218988 protein tyrosine phosphatase, mitochondrial 1
          isoform 2 [Homo sapiens]
          Length = 151

 Score =  120 bits (301), Expect = 8e-28
 Identities = 58/59 (98%), Positives = 59/59 (100%)

Query: 1  MAATALLEAGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQL 59
          MAATALLEAGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQ+
Sbjct: 1  MAATALLEAGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQV 59


>gi|239582767 slingshot homolog 3 [Homo sapiens]
          Length = 659

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 18/160 (11%)

Query: 33  AHRDWYHRIDPTVLLGALPLRSLTRQLVQDENVRGVITMNEE----YETRFLCNSSQEWK 88
           A RD   RI P + LG+    +   + +Q   V  ++ M  E    Y  RF  ++ + W 
Sbjct: 324 AQRDRASRIFPHLYLGS-EWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLW- 381

Query: 89  RLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLI 148
                       D      L + ++  +F    ++ G  V VHCK G SRSA  V AY +
Sbjct: 382 ------------DEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAM 429

Query: 149 QVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHKQITA 188
           + ++ S E+A+R + ++R      PG L  L+ +   +TA
Sbjct: 430 KQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTA 469


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 47.8 bits (112), Expect = 6e-06
 Identities = 30/84 (35%), Positives = 43/84 (51%)

Query: 111 LQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIH 170
           L K V F  K ++   CV VHC AG SRSAT+  AY+++    S +EA R + + R  I 
Sbjct: 223 LDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTIS 282

Query: 171 IRPGQLDVLKEFHKQITARATKDG 194
                L  L ++ K+I  +    G
Sbjct: 283 PNFNFLGQLLDYEKKIKNQTGASG 306


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 8/92 (8%)

Query: 105 IPTLDN--------LQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPE 156
           IP  DN          + + F    ++ G  V+VHC+AG SRSAT+  AYL++ ++   +
Sbjct: 223 IPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLD 282

Query: 157 EAVRAIAKIRSYIHIRPGQLDVLKEFHKQITA 188
           EA   + + RS I      +  L +F  Q+ A
Sbjct: 283 EAFEFVKQRRSIISPNFSFMGQLLQFESQVLA 314


>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
          Length = 184

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 28/94 (29%), Positives = 47/94 (50%)

Query: 91  GVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQV 150
           GV+ L +   D        + ++ ++F  + +  G+   VHC AG SRS T+V AY++ V
Sbjct: 47  GVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTV 106

Query: 151 HKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHK 184
             +  E+A+  +   RS  +   G    L+EF K
Sbjct: 107 TDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEK 140


>gi|51491914 dual specificity phosphatase and pro isomerase domain
           containing 1 [Homo sapiens]
          Length = 220

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 25/59 (42%), Positives = 36/59 (61%), Gaps = 1/59 (1%)

Query: 128 VYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHKQI 186
           + VHC  GRSRSAT+V AYL+     +  +A++ +AK R  +  R G L  L+E  KQ+
Sbjct: 143 ILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNR-GFLKQLRELDKQL 200


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 7/123 (5%)

Query: 64  NVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQS 123
           N+     +N    T   C +   +K + VE    + +         + Q+ + F    + 
Sbjct: 202 NLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADIS-------SHFQEAIDFIDCVRE 254

Query: 124 LGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFH 183
            G  V VHC+AG SRS T+  AYL++  ++  +EA   I + RS +    G +  L ++ 
Sbjct: 255 KGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYE 314

Query: 184 KQI 186
            +I
Sbjct: 315 SEI 317


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 27/91 (29%), Positives = 42/91 (46%)

Query: 92  VEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVH 151
           +  LR+   D   +P   + ++ + F    +  G    VHC AG SRS T+V AY++ V 
Sbjct: 48  ITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVT 107

Query: 152 KWSPEEAVRAIAKIRSYIHIRPGQLDVLKEF 182
                + + AI   R   +  PG    L+EF
Sbjct: 108 GLGWRDVLEAIKATRPIANPNPGFRQQLEEF 138


>gi|56786144 dual specificity phosphatase 23 [Homo sapiens]
          Length = 150

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 14/133 (10%)

Query: 49  ALPLRSLTRQLVQDENVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTL 108
           ALP      Q + D  VR ++++ E          S     L + +LR+        P  
Sbjct: 20  ALPRLPAHYQFLLDLGVRHLVSLTERGPPH-----SDSCPGLTLHRLRIPDFCP---PAP 71

Query: 109 DNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSY 168
           D + + VQ   +  + G+ V VHC  G  R+ TM+A YL++    +   A  AIA+IR  
Sbjct: 72  DQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLA---AGDAIAEIR-- 126

Query: 169 IHIRPGQLDVLKE 181
             +RPG ++  ++
Sbjct: 127 -RLRPGSIETYEQ 138


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 27/84 (32%), Positives = 40/84 (47%)

Query: 111 LQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIH 170
           L K ++F  K +     V VHC AG SRSAT+  AY+++    S ++A R +   R  I 
Sbjct: 225 LDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSIS 284

Query: 171 IRPGQLDVLKEFHKQITARATKDG 194
                L  L E+ + +   A   G
Sbjct: 285 PNFNFLGQLLEYERSLKLLAALQG 308


>gi|66346728 laforin isoform b [Homo sapiens]
          Length = 317

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 38  YHRIDPTVLLGALP--LRSLTRQLVQDENVRGVITMNEEYE---TRFLCNSSQE------ 86
           Y RI P + LG+ P  +  +T +L  +  +  V+    E++       CN   E      
Sbjct: 157 YSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDT 216

Query: 87  ----WKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATM 142
               ++  G+  + + T DM+    +  L + V         G  VYVHC AG  RS   
Sbjct: 217 MIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAA 276

Query: 143 VAAYLIQVHKWS 154
           V  +L  V  W+
Sbjct: 277 VCGWLQYVMGWN 288


>gi|11321613 laforin isoform a [Homo sapiens]
          Length = 331

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 38  YHRIDPTVLLGALP--LRSLTRQLVQDENVRGVITMNEEYE---TRFLCNSSQE------ 86
           Y RI P + LG+ P  +  +T +L  +  +  V+    E++       CN   E      
Sbjct: 157 YSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDT 216

Query: 87  ----WKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATM 142
               ++  G+  + + T DM+    +  L + V         G  VYVHC AG  RS   
Sbjct: 217 MIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAA 276

Query: 143 VAAYLIQVHKWS 154
           V  +L  V  W+
Sbjct: 277 VCGWLQYVMGWN 288


>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
          Length = 176

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 28/104 (26%), Positives = 46/104 (44%)

Query: 91  GVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQV 150
           GV +LR+   D      L +L+            G    V+CK GRSRSA +  AYL++ 
Sbjct: 62  GVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRH 121

Query: 151 HKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHKQITARATKDG 194
              S  +A + +   R      PG    L+++ + + A++   G
Sbjct: 122 RGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQG 165


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 24/61 (39%), Positives = 33/61 (54%)

Query: 128 VYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHKQIT 187
           V VHC+AG SRSAT+  AYL+   +   EEA   + + RS I      +  L +F  Q+ 
Sbjct: 276 VLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVL 335

Query: 188 A 188
           A
Sbjct: 336 A 336


>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
          Length = 303

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 24/61 (39%), Positives = 33/61 (54%)

Query: 128 VYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHKQIT 187
           V VHC+AG SRSAT+  AYL+   +   EEA   + + RS I      +  L +F  Q+ 
Sbjct: 185 VLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVL 244

Query: 188 A 188
           A
Sbjct: 245 A 245


>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
          Length = 211

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 85  QEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSL-GQCVYVHCKAGRSRSATMV 143
           + ++ LG+  L +   D        + Q    F  +  S  G  + VHC  G SRSAT+V
Sbjct: 104 EAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLV 163

Query: 144 AAYLIQVHKWSPEEAVRAIAKIRSYI 169
            AYL+  H  +  EA++ +   R  I
Sbjct: 164 LAYLMLYHHLTLVEAIKKVKDHRGII 189


>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
          Length = 314

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 8/90 (8%)

Query: 105 IPTLDN--------LQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPE 156
           IP  DN         Q+ + F    ++ G  V VHC+AG SRSAT+  AYL+Q  +   +
Sbjct: 222 IPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLD 281

Query: 157 EAVRAIAKIRSYIHIRPGQLDVLKEFHKQI 186
           EA   + + R  I      +  L +F  Q+
Sbjct: 282 EAFDFVKQRRGVISPNFSFMGQLLQFETQV 311


>gi|134142828 RNA guanylyltransferase and 5'-phosphatase [Homo
           sapiens]
          Length = 597

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 9/99 (9%)

Query: 91  GVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLG--QCVYVHCKAGRSRSATMVAAYLI 148
           G++ ++L        PT +N +  ++   ++      + + VHC  G +R+  ++ A+L+
Sbjct: 83  GIKYIKLQCKGHGECPTTENTETFIRLCERFNERNPPELIGVHCTHGFNRTGFLICAFLV 142

Query: 149 QVHKWSPEEAVRAIAKIRSYIHIRPG--QLDVLKEFHKQ 185
           +   WS E AV   A+ R      PG  + D LKE  ++
Sbjct: 143 EKMDWSIEAAVATFAQARP-----PGIYKGDYLKELFRR 176


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 21/67 (31%), Positives = 35/67 (52%)

Query: 116 QFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQ 175
           +F  K +  G    VHCK G SRSA+ V AY ++ + W+ + A   + + R+     P  
Sbjct: 376 KFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSF 435

Query: 176 LDVLKEF 182
           +  L+E+
Sbjct: 436 MRQLEEY 442


>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 25/96 (26%), Positives = 44/96 (45%)

Query: 96  RLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSP 155
           RL   D          ++  +F  +    G+ + +HC+AG SRSAT+V AYL++  + + 
Sbjct: 30  RLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTM 89

Query: 156 EEAVRAIAKIRSYIHIRPGQLDVLKEFHKQITARAT 191
            +A + +   R  I      +  L EF + +    T
Sbjct: 90  TDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVT 125


>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 25/96 (26%), Positives = 44/96 (45%)

Query: 96  RLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSP 155
           RL   D          ++  +F  +    G+ + +HC+AG SRSAT+V AYL++  + + 
Sbjct: 30  RLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTM 89

Query: 156 EEAVRAIAKIRSYIHIRPGQLDVLKEFHKQITARAT 191
            +A + +   R  I      +  L EF + +    T
Sbjct: 90  TDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVT 125


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 25/96 (26%), Positives = 44/96 (45%)

Query: 96  RLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSP 155
           RL   D          ++  +F  +    G+ + +HC+AG SRSAT+V AYL++  + + 
Sbjct: 372 RLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTM 431

Query: 156 EEAVRAIAKIRSYIHIRPGQLDVLKEFHKQITARAT 191
            +A + +   R  I      +  L EF + +    T
Sbjct: 432 TDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVT 467


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 22/62 (35%), Positives = 32/62 (51%)

Query: 130 VHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFHKQITAR 189
           VHC AG SRSAT+  AYL++ H     EA   +   R  I    G    L ++ +Q+  +
Sbjct: 109 VHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGK 168

Query: 190 AT 191
           +T
Sbjct: 169 ST 170


>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 130 VHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEF 182
           VHCK G SRSA+ V AY ++   W  E+A   + + RS      G +  L E+
Sbjct: 391 VHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEY 443


>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
          Length = 703

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 130 VHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEF 182
           VHCK G SRSA+ V AY ++   W  E+A   + + RS      G +  L E+
Sbjct: 402 VHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEY 454


>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
          Length = 692

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 130 VHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEF 182
           VHCK G SRSA+ V AY ++   W  E+A   + + RS      G +  L E+
Sbjct: 391 VHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEY 443


>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
          Length = 340

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 27/115 (23%), Positives = 55/115 (47%), Gaps = 5/115 (4%)

Query: 60  VQDENVRGVITMNEEYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFAL 119
           +++  +  V+T++ E  +       ++  RL V  L     D+     L +L + V F  
Sbjct: 48  LREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDL-----LSHLDRCVAFIG 102

Query: 120 KYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPG 174
           + ++ G+ V VHC AG SRS  ++ A+L++  +   E+A   +  ++    +  G
Sbjct: 103 QARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEG 157


>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
          Length = 1158

 Score = 36.6 bits (83), Expect = 0.015
 Identities = 48/193 (24%), Positives = 77/193 (39%), Gaps = 37/193 (19%)

Query: 36  DWYHRI----DPTVLLGALPLRSLTRQLVQDENVRGVITMNEEYETRFLCNSSQ-----E 86
           D Y+R+    D T L     +  L R LVQD        ++E +   F+   S       
Sbjct: 95  DLYNRVREKMDDTSLYNTPCVLDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGR 154

Query: 87  WKRLGVEQLRLSTVDMTGIPTLDNLQKGVQ-------------------FALKYQSLGQC 127
            KRLG+  + L+    TG+ T      G++                   F    + L + 
Sbjct: 155 LKRLGITHI-LNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFPEVDISQHFRKASEFLDEA 213

Query: 128 -------VYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLK 180
                  V V  + G SRSA +V AYL+  H  +  EA+  + K R+ I+   G L  L+
Sbjct: 214 LLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRKKRA-IYPNEGFLKQLR 272

Query: 181 EFHKQITARATKD 193
           E ++++     +D
Sbjct: 273 ELNEKLMEEREED 285


>gi|30089952 protein tyrosine phosphatase domain containing 1
           protein isoform 1 [Homo sapiens]
          Length = 806

 Score = 36.6 bits (83), Expect = 0.015
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 16/102 (15%)

Query: 87  WKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAY 146
           WK  GV  L           T+ ++ K + FAL+       V +HC AG  R+  ++A Y
Sbjct: 211 WKDYGVASLT----------TILDMVKVMTFALQEGK----VAIHCHAGLGRTGVLIACY 256

Query: 147 LIQVHKWSPEEAVRAI-AKIRSYIHIRPGQLDVLKEFHKQIT 187
           L+   + + ++A+  + AK  + I  R GQL  ++EF + +T
Sbjct: 257 LVFATRMTADQAIIFVRAKRPNSIQTR-GQLLCVREFTQFLT 297


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,641,404
Number of Sequences: 37866
Number of extensions: 241123
Number of successful extensions: 585
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 518
Number of HSP's gapped (non-prelim): 74
length of query: 201
length of database: 18,247,518
effective HSP length: 97
effective length of query: 104
effective length of database: 14,574,516
effective search space: 1515749664
effective search space used: 1515749664
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.