Search of human proteins with 145275206

Search of human proteins with 145275206

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145275206 methyltransferase like 4 [Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145275206 methyltransferase like 4 [Homo sapiens]                  966   0.0  
gi|21361827 methyltransferase like 3 [Homo sapiens]                    45   2e-04
gi|4502395 beclin 1 [Homo sapiens]                                     33   0.73 
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    32   0.96 
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    32   0.96 
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    32   0.96 
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     30   4.7  
gi|157785548 PAS domain containing 1 [Homo sapiens]                    30   4.7  
gi|217330592 LGP1 homolog isoform 2 [Homo sapiens]                     29   8.1  
gi|58761537 hypothetical protein LOC84437 [Homo sapiens]               29   8.1  
gi|30794488 kinesin family member 27 [Homo sapiens]                    29   8.1  

>gi|145275206 methyltransferase like 4 [Homo sapiens]
          Length = 472

 Score =  966 bits (2497), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MSVVHQLSAGWLLDHLSFINKINYQLHQHHEPCCRKKEFTTSVHFESLQMDSVSSSGVCA 60
           MSVVHQLSAGWLLDHLSFINKINYQLHQHHEPCCRKKEFTTSVHFESLQMDSVSSSGVCA
Sbjct: 1   MSVVHQLSAGWLLDHLSFINKINYQLHQHHEPCCRKKEFTTSVHFESLQMDSVSSSGVCA 60

Query: 61  AFIASDSSTKPENDDGGNYEMFTRKFVFRPELFDVTKPYITPAVHKECQQSNEKEDLMNG 120
           AFIASDSSTKPENDDGGNYEMFTRKFVFRPELFDVTKPYITPAVHKECQQSNEKEDLMNG
Sbjct: 61  AFIASDSSTKPENDDGGNYEMFTRKFVFRPELFDVTKPYITPAVHKECQQSNEKEDLMNG 120

Query: 121 VKKEISISIIGKKRKRCVVFNQGELDAMEYHTKIRELILDGSLQLIQEGLKSGFLYPLFE 180
           VKKEISISIIGKKRKRCVVFNQGELDAMEYHTKIRELILDGSLQLIQEGLKSGFLYPLFE
Sbjct: 121 VKKEISISIIGKKRKRCVVFNQGELDAMEYHTKIRELILDGSLQLIQEGLKSGFLYPLFE 180

Query: 181 KQDKGSKPITLPLDACSLSELCEMAKHLPSLNEMEHQTLQLVEEDTSVTEQDLFLRVVEN 240
           KQDKGSKPITLPLDACSLSELCEMAKHLPSLNEMEHQTLQLVEEDTSVTEQDLFLRVVEN
Sbjct: 181 KQDKGSKPITLPLDACSLSELCEMAKHLPSLNEMEHQTLQLVEEDTSVTEQDLFLRVVEN 240

Query: 241 NSSFTKVITLMGQKYLLPPKSSFLLSDISCMQPLLNYRKTFDVIVIDPPWQNKSVKRSNR 300
           NSSFTKVITLMGQKYLLPPKSSFLLSDISCMQPLLNYRKTFDVIVIDPPWQNKSVKRSNR
Sbjct: 241 NSSFTKVITLMGQKYLLPPKSSFLLSDISCMQPLLNYRKTFDVIVIDPPWQNKSVKRSNR 300

Query: 301 YSYLSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKEELYPSWSVEVVAEWHWVKIT 360
           YSYLSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKEELYPSWSVEVVAEWHWVKIT
Sbjct: 301 YSYLSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKEELYPSWSVEVVAEWHWVKIT 360

Query: 361 NSGEFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNVLPIPDHKLIVSVPCTLHSHK 420
           NSGEFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNVLPIPDHKLIVSVPCTLHSHK
Sbjct: 361 NSGEFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNVLPIPDHKLIVSVPCTLHSHK 420

Query: 421 PPLAEVLKDYIKPDGEYLELFARNLQPGWTSWGNEVLKFQHVDYFIAVESGS 472
           PPLAEVLKDYIKPDGEYLELFARNLQPGWTSWGNEVLKFQHVDYFIAVESGS
Sbjct: 421 PPLAEVLKDYIKPDGEYLELFARNLQPGWTSWGNEVLKFQHVDYFIAVESGS 472


>gi|21361827 methyltransferase like 3 [Homo sapiens]
          Length = 580

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 17/178 (9%)

Query: 281 FDVIVIDPPWQNKSVKRSNRYSYLSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKE 340
           F V++ DPPW    +     Y  L+  +++++ IP L     L + WVT R   L     
Sbjct: 389 FAVVMADPPW---DIHMELPYGTLTDDEMRRLNIPVLQDDGFLFL-WVTGRAMEL---GR 441

Query: 341 ELYPSWSVEVVAEWHWVKITNSGEFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNV 400
           E    W  E V E  WVK       +       +    G  L   +E   + ++      
Sbjct: 442 ECLNLWGYERVDEIIWVKTNQLQRII-------RTGRTGHWLNHGKEHCLVGVKGNPQGF 494

Query: 401 LPIPDHKLIVSVPCTLHSHKPPLAEVLKDYIKPDGEYLELFAR--NLQPGWTSWGNEV 456
               D  +IV+      SHKP     + + + P    +ELF R  N+QP W + GN++
Sbjct: 495 NQGLDCDVIVA-EVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQL 551


>gi|4502395 beclin 1 [Homo sapiens]
          Length = 450

 Score = 32.7 bits (73), Expect = 0.73
 Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 25/197 (12%)

Query: 46  ESLQMDSVSSSGVCAAFIASDSSTKP-----ENDDGGNYEMFTRKFVFRPELFDVTKPYI 100
           E+ + D VS   +  A + S  S        E  DGG  E  +R+     +LFD+     
Sbjct: 71  ETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQ- 129

Query: 101 TPAVHKECQQSNEKEDLMNGVKKEISISIIG-KKRKRC--VVFNQGELDAMEYHTKIREL 157
           T   H  C++    + L++ +  +++++    +  KRC  ++    E D+ +   +++EL
Sbjct: 130 TDVDHPLCEECT--DTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKEL 187

Query: 158 ILDGSLQLIQEGLKSGFLYPLFEKQDKGSKPITLPLDACSLSEL---CEMAKHLPSLNEM 214
            L+   +LIQE           E  +K  K +   L+           E A++    +E 
Sbjct: 188 ALEEE-RLIQE----------LEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEF 236

Query: 215 EHQTLQLVEEDTSVTEQ 231
           + Q L+L +E  SV  Q
Sbjct: 237 KRQQLELDDELKSVENQ 253


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 20/159 (12%)

Query: 253 QKYLLPPKSSFLLSD-----ISCMQP--LLNYRK-TFDVIVIDPPWQNKSV-KRSNRYSY 303
           +K LLPP  S   +      +S  QP  + +Y+  +F  + ++  WQ KS   R+     
Sbjct: 801 KKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGS 860

Query: 304 LSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKEELYPSWSVEVVAEWHWVKITNSG 363
           +SP+  Q   +  L A    L +W   +  HL F K ++     +E    W W    + G
Sbjct: 861 VSPIHGQGQVVENLKAQ--ALCSWTAKKDNHLNFSKHDIIT--VLEQQENW-WFGEVHGG 915

Query: 364 EFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNVLP 402
              FP      K Y  +I G   ++       A VN  P
Sbjct: 916 RGWFP------KSYVKIIPGSEVKREEPEALYAAVNKKP 948


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 20/159 (12%)

Query: 253 QKYLLPPKSSFLLSD-----ISCMQP--LLNYRK-TFDVIVIDPPWQNKSV-KRSNRYSY 303
           +K LLPP  S   +      +S  QP  + +Y+  +F  + ++  WQ KS   R+     
Sbjct: 828 KKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGS 887

Query: 304 LSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKEELYPSWSVEVVAEWHWVKITNSG 363
           +SP+  Q   +  L A    L +W   +  HL F K ++     +E    W W    + G
Sbjct: 888 VSPIHGQGQVVENLKAQ--ALCSWTAKKDNHLNFSKHDIIT--VLEQQENW-WFGEVHGG 942

Query: 364 EFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNVLP 402
              FP      K Y  +I G   ++       A VN  P
Sbjct: 943 RGWFP------KSYVKIIPGSEVKREEPEALYAAVNKKP 975


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 20/159 (12%)

Query: 253 QKYLLPPKSSFLLSD-----ISCMQP--LLNYRK-TFDVIVIDPPWQNKSV-KRSNRYSY 303
           +K LLPP  S   +      +S  QP  + +Y+  +F  + ++  WQ KS   R+     
Sbjct: 828 KKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGS 887

Query: 304 LSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKEELYPSWSVEVVAEWHWVKITNSG 363
           +SP+  Q   +  L A    L +W   +  HL F K ++     +E    W W    + G
Sbjct: 888 VSPIHGQGQVVENLKAQ--ALCSWTAKKDNHLNFSKHDIIT--VLEQQENW-WFGEVHGG 942

Query: 364 EFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNVLP 402
              FP      K Y  +I G   ++       A VN  P
Sbjct: 943 RGWFP------KSYVKIIPGSEVKREEPEALYAAVNKKP 975


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 52/198 (26%), Positives = 82/198 (41%), Gaps = 19/198 (9%)

Query: 253 QKYLLPPKSSFLLSDISCMQPLLNYRKTFDVIVIDPPWQNK--SVKRSNRYSYLSPLQIQ 310
           Q   +P  +S LLS +   +P    RK+F + V + P ++   S+K    + +    ++ 
Sbjct: 311 QSAAVPAPTSQLLSSLEKDEP----RKSFGIKVQNLPVRSTDTSLKDGLFHEFKKFGKVT 366

Query: 311 QIPIPKLAAPNCLLVTW--VTNRQKHLRFIKEELYPSWSVEVVAEWHWVKITNSGEFVF- 367
            + I   +     LV +    +++K L   K +L+    +EV A   W+      E  F 
Sbjct: 367 SVQIHGTSEERYGLVFFRQQEDQEKALTASKGKLFFGMQIEVTA---WIGPETESENEFR 423

Query: 368 PLDSP----HKKPYEGLILGRVQEKTAL-PLRNADVNVLPIPDH--KLIVSVPCTLHSHK 420
           PLD      H K    L +G +++ T    LRN       I D   K +  VP       
Sbjct: 424 PLDERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKVNGVPQYAFLQY 483

Query: 421 PPLAEVLKDYIKPDGEYL 438
             +A V K   K DGEYL
Sbjct: 484 CDIASVCKAIKKMDGEYL 501


>gi|157785548 PAS domain containing 1 [Homo sapiens]
          Length = 773

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 17/52 (32%), Positives = 27/52 (51%)

Query: 120 GVKKEISISIIGKKRKRCVVFNQGELDAMEYHTKIRELILDGSLQLIQEGLK 171
           G+    S+   G+ ++ CV FNQ +L   E H K ++  L   LQ ++E  K
Sbjct: 457 GLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRK 508


>gi|217330592 LGP1 homolog isoform 2 [Homo sapiens]
          Length = 491

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 14/113 (12%)

Query: 275 LNYRKTFDVIVIDPPWQNKSVKRSNRYSYLSPLQIQQIPIPKLAAPNCLL--VTWVTNRQ 332
           L +R  +  +V    WQ + +++S  + + S  Q  +  +     P+C L   T ++  +
Sbjct: 35  LQHRVAWGALVWAATWQRRRLEQSTLHVHQSQQQALRWCLQGAQRPHCSLRRSTDISTFR 94

Query: 333 KHLRFIKEELYPSWSVEVVAEWHWVKITNSGEFVFPLDSPHKKPYEGLILGRV 385
            HL   K   YP    EV+A+    ++T +  +  PL      P+ G  LG+V
Sbjct: 95  NHLPLTK--AYP----EVLAQGRTARVTLTSPWPRPL------PWPGNTLGQV 135


>gi|58761537 hypothetical protein LOC84437 [Homo sapiens]
          Length = 345

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 4/58 (6%)

Query: 203 EMAKHLPSLNEMEHQTLQLVEEDTSVTEQDLFLRVVENNSSFTKVITLMGQKYLLPPK 260
           E  +HL    +MEH+ LQL +E   +  + L L++V +     +     G+K +L P+
Sbjct: 238 ERLRHL----DMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQ 291


>gi|30794488 kinesin family member 27 [Homo sapiens]
          Length = 1401

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 122 KKEISISIIGKKRKRCVVFNQGELDAMEYHT-----KIRE-----LILDGSLQLIQEGLK 171
           KK  S+SI  +KR   +   +  +D M+Y       K+RE       LD  ++  Q+ +K
Sbjct: 825 KKLASLSIQNEKRANEL---EQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIK 881

Query: 172 SGFLYPLFEKQDKGSKPITLPLDACSLSELCEMAKHLPSLNEMEHQTLQLVEEDTSVTEQ 231
                 L   Q++G KP    LDAC+L         +  L +++ Q   L EE   V  Q
Sbjct: 882 E---IQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQ 938

Query: 232 DLFLRVVE 239
              L  +E
Sbjct: 939 RQELEELE 946


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,821,648
Number of Sequences: 37866
Number of extensions: 858344
Number of successful extensions: 1928
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1924
Number of HSP's gapped (non-prelim): 13
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.