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Search of human proteins with 9994201
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9994201 carboxypeptidase X, member 1 precursor [Homo
sapiens]
(734 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 1526 0.0
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 781 0.0
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 660 0.0
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 394 e-109
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 394 e-109
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 394 e-109
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 394 e-109
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 380 e-105
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 347 2e-95
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 249 6e-66
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 249 6e-66
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 249 6e-66
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho... 96 9e-20
gi|31317224 EGF-like repeats and discoidin I-like domains-contai... 93 8e-19
gi|10835083 X-linked juvenile retinoschisis protein precursor [H... 87 4e-17
gi|105990535 coagulation factor V precursor [Homo sapiens] 86 1e-16
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa... 82 1e-15
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap... 82 1e-15
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 79 2e-14
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 79 2e-14
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 79 2e-14
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 79 2e-14
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 79 2e-14
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 79 2e-14
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 79 2e-14
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa... 74 5e-13
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2... 72 2e-12
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1... 72 2e-12
gi|239743729 PREDICTED: similar to contactin associated protein-... 72 2e-12
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens] 72 2e-12
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 1526 bits (3952), Expect = 0.0
Identities = 734/734 (100%), Positives = 734/734 (100%)
Query: 1 MWGLLLALAAFAPAVGPALGAPRNSVLGLAQPGTTKVPGSTPALHSSPAQPPAETANGTS 60
MWGLLLALAAFAPAVGPALGAPRNSVLGLAQPGTTKVPGSTPALHSSPAQPPAETANGTS
Sbjct: 1 MWGLLLALAAFAPAVGPALGAPRNSVLGLAQPGTTKVPGSTPALHSSPAQPPAETANGTS 60
Query: 61 EQHVRIRVIKKKKVIMKKRKKLTLTRPTPLVTAGPLVTPTPAGTLDPAEKQETGCPPLGL 120
EQHVRIRVIKKKKVIMKKRKKLTLTRPTPLVTAGPLVTPTPAGTLDPAEKQETGCPPLGL
Sbjct: 61 EQHVRIRVIKKKKVIMKKRKKLTLTRPTPLVTAGPLVTPTPAGTLDPAEKQETGCPPLGL 120
Query: 121 ESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGH 180
ESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGH
Sbjct: 121 ESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGH 180
Query: 181 PTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVL 240
PTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVL
Sbjct: 181 PTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVL 240
Query: 241 NLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHH 300
NLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHH
Sbjct: 241 NLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHH 300
Query: 301 NYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMH 360
NYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMH
Sbjct: 301 NYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMH 360
Query: 361 GNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVG 420
GNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVG
Sbjct: 361 GNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVG 420
Query: 421 WAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETR 480
WAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETR
Sbjct: 421 WAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETR 480
Query: 481 AVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSN 540
AVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSN
Sbjct: 481 AVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSN 540
Query: 541 LAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHE 600
LAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHE
Sbjct: 541 LAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHE 600
Query: 601 NELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDY 660
NELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDY
Sbjct: 601 NELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDY 660
Query: 661 WRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTKTPKQRLRELLAAGAKVPP 720
WRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTKTPKQRLRELLAAGAKVPP
Sbjct: 661 WRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTKTPKQRLRELLAAGAKVPP 720
Query: 721 DLRRRLERLRGQKD 734
DLRRRLERLRGQKD
Sbjct: 721 DLRRRLERLRGQKD 734
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 781 bits (2016), Expect = 0.0
Identities = 377/695 (54%), Positives = 480/695 (69%), Gaps = 14/695 (2%)
Query: 48 PAQPPAETANGTSEQHVRIRVIKKKKVIMKKRKKLTLTRPTPLVTAGPLVTPTPAGTLDP 107
PA P E E R K KK KR+K P P + V T +
Sbjct: 62 PAGPGEEWERRPQEPRPPKRATKPKKA--PKREKSAPEPPPPGKHSNKKVMRTKSSEKAA 119
Query: 108 ---------AEKQETGCPPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDL 158
E CPPLGLE+L+++D +L AS+ + +GLG HRGRLNIQ+G+ + D
Sbjct: 120 NDDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDF 179
Query: 159 YDGAWCAEEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGS 218
YDGAWCA D W +VDA TRF+GVITQGRNS+W DWVTSYKV SNDS TW
Sbjct: 180 YDGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTV 239
Query: 219 RNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
+N S D +F NS+ E PVLN LP P VAR+IR+ PQ+W G+ C+R EIL CP+ D
Sbjct: 240 KNGSG--DMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
Query: 279 PNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVME 338
PN+ + ++D LDF+HHNYK MR+LMK V E CPNITRIY+IGKS+QGLKLY +E
Sbjct: 298 PNNYYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVE 357
Query: 339 MSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIH 398
+SD PGEHE+GEPE Y+AG HGNE LGRELLLLL+QF+C E+L N R+ L+ E RIH
Sbjct: 358 ISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIH 417
Query: 399 LLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVP 458
+LPS+NPDGYE AY GSEL GW+ GRW + ID+N+NF DLNT LWEA+D VP VP
Sbjct: 418 VLPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVP 477
Query: 459 NHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAAR 518
NH++ +P ++ NATVA ETRAVI WM++IPFVL NL GGELVV+YP+D+ R+PW +
Sbjct: 478 NHYIAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQ 537
Query: 519 ELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDF 578
E TPTPDD VFRWL+ YA ++ M D RR CH++DF +NGA WHTV GS+NDF
Sbjct: 538 EHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDF 597
Query: 579 SYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGI 638
SYLHTNCFE+++ + CDK+PHE++LP+EWENN+++L+ ++EQV GI G+VRD + GI
Sbjct: 598 SYLHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGK-GI 656
Query: 639 ADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNF 698
+A+I+V+GINHD+ TA GDYWRLL PG+Y+VTA AEG+ + T+NC V ++ G C+F
Sbjct: 657 PNAIISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDF 716
Query: 699 VLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQK 733
L+KT R+RE++ K P L R +LRGQK
Sbjct: 717 TLSKTNMARIREIMEKFGKQPVSLPARRLKLRGQK 751
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 660 bits (1702), Expect = 0.0
Identities = 330/631 (52%), Positives = 429/631 (67%), Gaps = 26/631 (4%)
Query: 107 PAEKQETGCPPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAE 166
P EK + CPP+G+ES R+ D+++ ASS GLG RGRLN+Q+G + D YDGAWCAE
Sbjct: 379 PTEKVK--CPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAE 436
Query: 167 EQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMD 226
+ W +VD TRF+GVITQGR+S D+VT++ V FSNDS+TW N M
Sbjct: 437 DDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEM- 495
Query: 227 AVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEA 286
F N D +TPVL+ LPEP VARFIR+ P TW G+ C+R E+L C V+ + +
Sbjct: 496 -TFHGNVDKDTPVLSELPEPVVARFIRIYPLTW--NGSLCMRLEVLGCSVAPVYSYYAQN 552
Query: 287 PASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEH 346
+ D LDF+HH+YK MR+LMK V E+CP ITR YS+GKS +GLK+Y ME+SD PGEH
Sbjct: 553 EVVATDD-LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEH 611
Query: 347 ELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPD 406
ELGEPE RY AG+HGNE LGRELLLLLMQ+LC E+ GNPRV L+ + RIHL+PS+NPD
Sbjct: 612 ELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPD 671
Query: 407 GYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPT 466
GYE+A GSE WA G W + D+ +F DLN+ LW A++ VP+ VPN++LP+P
Sbjct: 672 GYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPE 731
Query: 467 YYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPW----------A 516
Y P+ATV+ E RA+I WM++ PFVL ANL+GGE +VSYP+DM RTP A
Sbjct: 732 RYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAA 791
Query: 517 AR--------ELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADW 568
AR E TPD A+FRWL+ +A ++L + + R C +QD++ I+NGA W
Sbjct: 792 ARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKW 851
Query: 569 HTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGV 628
+ G++NDFSYLHTNC E++ L CDKFPHE+ELP+EWENNK+ALLT++EQV GI GV
Sbjct: 852 NPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGV 911
Query: 629 VRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVT 688
V D + + IA+A I+V GINH V TA GGDYWR+L PG+Y VTA AEGY + C V
Sbjct: 912 VTD-EQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVD 970
Query: 689 FEEGPFPCNFVLTKTPKQRLRELLAAGAKVP 719
++ G CNF+L ++ +R+RE++A P
Sbjct: 971 YDIGATQCNFILARSNWKRIREIMAMNGNRP 1001
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 394 bits (1012), Expect = e-109
Identities = 200/416 (48%), Positives = 278/416 (66%), Gaps = 20/416 (4%)
Query: 286 APASG--------SSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVM 337
APA+G D + F++H Y +R+ + V QC I+RIY++G+S++G +L V+
Sbjct: 32 APAAGMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVI 91
Query: 338 EMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRI 397
E+SD PG HE GEPE +Y+ MHGNEA+GRELL+ L Q+LC+E+ +GN + L+ RI
Sbjct: 92 ELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRI 151
Query: 398 HLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIV 457
H++PS+NPDG+E A + EL W GR N Q IDLN NF DL+ ++ + +G
Sbjct: 152 HIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGG----- 206
Query: 458 PNHHLPLPTYYTL--PNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPW 515
PN+HL L + N +APET+AVI W+ IPFVLSANLHGG+LV +YP+D TR+
Sbjct: 207 PNNHL-LKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRS-G 264
Query: 516 AARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPC--HSQDFSVHGNIINGADWHTVPG 573
+A E + +PDDA+F+ L+ Y+ N AM D +R PC + D S NG W++VPG
Sbjct: 265 SAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPG 324
Query: 574 SMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKD 633
M DF+YL +NCFE+TVELSC+KFP E L WE+NK++L++YLEQ+ G+ G VRD
Sbjct: 325 GMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQ 384
Query: 634 TELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTF 689
IA+A I+V+GI+HDVT+A GDYWRLL PG+Y +TASA GY ++T+ V +
Sbjct: 385 GN-PIANATISVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPY 439
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 394 bits (1011), Expect = e-109
Identities = 194/388 (50%), Positives = 264/388 (68%), Gaps = 10/388 (2%)
Query: 297 FQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYV 356
F HH+Y M +++++ +C ++ R YSIG+S+ G +L V+E S +PG+HEL EPEV+ +
Sbjct: 48 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 107
Query: 357 AGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGS 416
+HGNE GRE+L+ L Q+LC E+L GNPR+ RLL+ RIHLLPSMNPDGYE+A G+
Sbjct: 108 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 167
Query: 417 ELVGWAEGRWNNQSIDLNHNFADLNTPLWE-AQDDGKVPHIVPNHHLPLPTYYTLPNATV 475
GW GR N Q++DLN NF DL + + A+ G + H+P+P +Y V
Sbjct: 168 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRG-----ARSDHIPIPQHYWW--GKV 220
Query: 476 APETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTV 535
APET+A++KWM+ IPFVLSA+LHGG+LVVSYPFD ++ P + +PTPD+ +F+ LS
Sbjct: 221 APETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRA 280
Query: 536 YAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCD 595
YA + M D S C +F G+IINGADW++ G M+DF+YLHTNCFE+TVEL C
Sbjct: 281 YADVHPMMMDRSENRC-GGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCV 339
Query: 596 KFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTA 655
KFP E L W++NK++LL ++E V GI GVV DK + + +A I+V GI HD+TTA
Sbjct: 340 KFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGK-PVKNARISVKGIRHDITTA 398
Query: 656 WGGDYWRLLTPGDYMVTASAEGYHSVTR 683
GDYWRLL PG ++V A A GY V +
Sbjct: 399 PDGDYWRLLPPGIHIVIAQAPGYAKVIK 426
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 394 bits (1011), Expect = e-109
Identities = 194/388 (50%), Positives = 264/388 (68%), Gaps = 10/388 (2%)
Query: 297 FQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYV 356
F HH+Y M +++++ +C ++ R YSIG+S+ G +L V+E S +PG+HEL EPEV+ +
Sbjct: 174 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 233
Query: 357 AGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGS 416
+HGNE GRE+L+ L Q+LC E+L GNPR+ RLL+ RIHLLPSMNPDGYE+A G+
Sbjct: 234 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 293
Query: 417 ELVGWAEGRWNNQSIDLNHNFADLNTPLWE-AQDDGKVPHIVPNHHLPLPTYYTLPNATV 475
GW GR N Q++DLN NF DL + + A+ G + H+P+P +Y V
Sbjct: 294 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRG-----ARSDHIPIPQHYWW--GKV 346
Query: 476 APETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTV 535
APET+A++KWM+ IPFVLSA+LHGG+LVVSYPFD ++ P + +PTPD+ +F+ LS
Sbjct: 347 APETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRA 406
Query: 536 YAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCD 595
YA + M D S C +F G+IINGADW++ G M+DF+YLHTNCFE+TVEL C
Sbjct: 407 YADVHPMMMDRSENRC-GGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCV 465
Query: 596 KFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTA 655
KFP E L W++NK++LL ++E V GI GVV DK + + +A I+V GI HD+TTA
Sbjct: 466 KFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGK-PVKNARISVKGIRHDITTA 524
Query: 656 WGGDYWRLLTPGDYMVTASAEGYHSVTR 683
GDYWRLL PG ++V A A GY V +
Sbjct: 525 PDGDYWRLLPPGIHIVIAQAPGYAKVIK 552
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 394 bits (1011), Expect = e-109
Identities = 194/388 (50%), Positives = 264/388 (68%), Gaps = 10/388 (2%)
Query: 297 FQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYV 356
F HH+Y M +++++ +C ++ R YSIG+S+ G +L V+E S +PG+HEL EPEV+ +
Sbjct: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
Query: 357 AGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGS 416
+HGNE GRE+L+ L Q+LC E+L GNPR+ RLL+ RIHLLPSMNPDGYE+A G+
Sbjct: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
Query: 417 ELVGWAEGRWNNQSIDLNHNFADLNTPLWE-AQDDGKVPHIVPNHHLPLPTYYTLPNATV 475
GW GR N Q++DLN NF DL + + A+ G + H+P+P +Y V
Sbjct: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRG-----ARSDHIPIPQHYWW--GKV 357
Query: 476 APETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTV 535
APET+A++KWM+ IPFVLSA+LHGG+LVVSYPFD ++ P + +PTPD+ +F+ LS
Sbjct: 358 APETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRA 417
Query: 536 YAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCD 595
YA + M D S C +F G+IINGADW++ G M+DF+YLHTNCFE+TVEL C
Sbjct: 418 YADVHPMMMDRSENRC-GGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCV 476
Query: 596 KFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTA 655
KFP E L W++NK++LL ++E V GI GVV DK + + +A I+V GI HD+TTA
Sbjct: 477 KFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGK-PVKNARISVKGIRHDITTA 535
Query: 656 WGGDYWRLLTPGDYMVTASAEGYHSVTR 683
GDYWRLL PG ++V A A GY V +
Sbjct: 536 PDGDYWRLLPPGIHIVIAQAPGYAKVIK 563
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 380 bits (976), Expect = e-105
Identities = 214/447 (47%), Positives = 283/447 (63%), Gaps = 25/447 (5%)
Query: 294 PLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEV 353
P+ F+HH Y + + + +VQ +CP ITR+YSIG+S +G LYV+E SD PG HE EPEV
Sbjct: 20 PVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEV 79
Query: 354 RYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYH 413
+YV MHGNEALGREL+L L +FLC EF N R+ +L+ + RIH+LPSMNPDGYE+A
Sbjct: 80 KYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAA 139
Query: 414 RGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNA 473
+G G+ GR N +DLN NF DLNT ++ + G PNHHLPLP + +
Sbjct: 140 QGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGG-----PNHHLPLPDNW---KS 191
Query: 474 TVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMT---RTPWAAREL-TPTPDDAVF 529
V PETRAVI+WM FVLSANLHGG +V +YP+D + R R TPTPDD +F
Sbjct: 192 QVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLF 251
Query: 530 RWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVT 589
+ L+ VY+ ++ M + + D+ G I NGA W+++ M DF+YLHTNCFE+T
Sbjct: 252 QKLAKVYSYAHGWM----FQGWNCGDYFPDG-ITNGASWYSLSKGMQDFNYLHTNCFEIT 306
Query: 590 VELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGIN 649
+ELSCDKFP E EL +EW N++AL+ +LEQV GI G+V D++ +A+AVI+V GIN
Sbjct: 307 LELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYN-NLANAVISVSGIN 365
Query: 650 HDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTK-----TP 704
HDVT+ GDY+RLL PG Y V+A+A GY T V E P NF L + +P
Sbjct: 366 HDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAE-PTLVNFHLKRSIPQVSP 424
Query: 705 KQRL-RELLAAGAKVPPDLRRRLERLR 730
+R AKV P R++ +R
Sbjct: 425 VRRAPSRRHGVRAKVQPQARKKEMEMR 451
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 347 bits (890), Expect = 2e-95
Identities = 197/434 (45%), Positives = 255/434 (58%), Gaps = 40/434 (9%)
Query: 273 ACPVSDPNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGL 332
A V+ PN L + + P DF HH++ M +++ + PNITR+YS+GKS +
Sbjct: 477 ASTVAIPNILSGTSSSYQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESR 536
Query: 333 KLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLL 392
+LYVME+SD PG HE GEPE +Y+ MHGNE +GRELLL L+++LC F +P VT L+
Sbjct: 537 ELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNF-GTDPEVTDLV 595
Query: 393 SEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGK 452
RIHL+PSMNPDGYE + S V GR N+ + DLN NF D + +
Sbjct: 596 HNTRIHLMPSMNPDGYEKSQEGDSISV---IGRNNSNNFDLNRNFPDQFVQITD------ 646
Query: 453 VPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTR 512
PT PET AV+ WMK PFVLSANLHGG LVV+YPFD
Sbjct: 647 ------------PTQ---------PETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDE 685
Query: 513 TPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPC---HSQDFSVHGNIINGADWH 569
A + +PDDAVF+ ++ Y+ N M RPC + ++ HG I NGA W+
Sbjct: 686 QGLAT--YSKSPDDAVFQQIALSYSKENSQM--FQGRPCKNMYPNEYFPHG-ITNGASWY 740
Query: 570 TVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVV 629
VPG M D++YL TNCFEVT+EL C K+P E ELP WE N+ +L+ +++QV G+ G V
Sbjct: 741 NVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFV 800
Query: 630 RDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTF 689
D GI +A I+V INH VTT GDYWRLL PG Y +TASA GY+ VT+N V
Sbjct: 801 LDATDGRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVK- 859
Query: 690 EEGPFPCNFVLTKT 703
EG NF L ++
Sbjct: 860 SEGAIQVNFTLVRS 873
Score = 262 bits (670), Expect = 7e-70
Identities = 153/431 (35%), Positives = 231/431 (53%), Gaps = 48/431 (11%)
Query: 286 APASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMS----- 340
A A + D +H + L + P + R++SIG+S +G L+V+ ++
Sbjct: 46 AGAEAAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGS 105
Query: 341 --------------DKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNP 386
D G G P+V+ V MHG+E + R++L+ L + L + RG+P
Sbjct: 106 LIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDP 165
Query: 387 RVTRLLSEMRIHLLPSMNPDGYEIAYHR----GSELVGWAEGRWNNQSIDLNHNFADLNT 442
R+ RLL+ ++LLPS+NPDG+E A G A GR N++ DLN +F D +
Sbjct: 166 RLVRLLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFS 225
Query: 443 PLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGEL 502
G+ P + PE RA+I+W++R FVLS NLHGG +
Sbjct: 226 T-------GEPPAL-----------------DEVPEVRALIEWIRRNKFVLSGNLHGGSV 261
Query: 503 VVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNI 562
V SYPFD + A + T DD VF++L+ YA ++ M+ +D + I
Sbjct: 262 VASYPFDDSPEHKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGI 321
Query: 563 INGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVR 622
NGA W+ V G M D++Y+ NCFE+T+ELSC K+P ++L QEWENN+++L+T +E+V
Sbjct: 322 TNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVH 381
Query: 623 MGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVT 682
+G+ G V+D T G+ +A I+V GINH++TT GD++RLL PG Y +T GY +T
Sbjct: 382 IGVKGFVKDSITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLT 441
Query: 683 RNCRVTFEEGP 693
V +EGP
Sbjct: 442 VT-NVVVKEGP 451
Score = 190 bits (482), Expect = 5e-48
Identities = 121/385 (31%), Positives = 204/385 (52%), Gaps = 52/385 (13%)
Query: 297 FQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYV 356
+++H+YK + + ++ + P+IT + ++G+S + ++ +E+S+KP E EP++R+V
Sbjct: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
Query: 357 AGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRG- 415
AG+HGN +G ELLL L +FLC + + NP VT+L+ RI ++PS+NPDG E A +
Sbjct: 991 AGIHGNAPVGTELLLALAEFLCLNYKK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDC 1049
Query: 416 SELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATV 475
+ +G R + D +N +
Sbjct: 1050 TSKIGQTNARGKDLDTDFTNNASQ------------------------------------ 1073
Query: 476 APETRAVIK-WMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLST 534
PET+A+I+ +++ F LS L GG ++V+YP+D + + + + L++
Sbjct: 1074 -PETKAIIENLIQKQDFSLSVALDGGSMLVTYPYD--------KPVQTVENKETLKHLAS 1124
Query: 535 VYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSC 594
+YA ++ +M + D ++ G ++ GA+WH+ GSM D+S + +C E+TV SC
Sbjct: 1125 LYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSC 1184
Query: 595 DKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAV-DGINHDVT 653
FP LP W +NK +LL+ L +V G+ G V+DK T I+ AVI + +GI V
Sbjct: 1185 CYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDK-TGKPISKAVIVLNEGIK--VQ 1241
Query: 654 TAWGGDYWRLLTPGDYMVTASAEGY 678
T GG + LL PG + + A A+GY
Sbjct: 1242 TKEGGYFHVLLAPGVHNIIAIADGY 1266
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 249 bits (636), Expect = 6e-66
Identities = 142/387 (36%), Positives = 211/387 (54%), Gaps = 38/387 (9%)
Query: 295 LDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVR 354
LDF +H + M +K V + ++T ++SIGKS +G L+V+ + P EH +G PE +
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 355 YVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHR 414
YVA MHG+E +GRELLL L+ +L + +P +T L++ RIH++PSMNPDG+E
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Query: 415 GSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNAT 474
++ GR N DLN NF D + N +
Sbjct: 137 DCY---YSIGRENYNQYDLNRNFPDA---------------------------FEYNNVS 166
Query: 475 VAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDM-TRTPWAARELTPTPDDAVFRWLS 533
PET AV+KW+K FVLSANLHGG LV SYPFD + A + TPDD VF++L+
Sbjct: 167 RQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
Query: 534 TVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELS 593
YA N M+ C ++ + + NG W+ + G M D++Y+ CFE+T+ELS
Sbjct: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 594 CDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINH--D 651
C K+P E +LP W NNK +L+ Y++QV +G+ G V D++ + + ++ V H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN-PLPNVIVEVQDRKHICP 342
Query: 652 VTTAWGGDYWRLLTPGDYMVTASAEGY 678
T G+Y+ LL PG Y++ + G+
Sbjct: 343 YRTNKYGEYYLLLLPGSYIINVTVPGH 369
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 249 bits (636), Expect = 6e-66
Identities = 142/387 (36%), Positives = 211/387 (54%), Gaps = 38/387 (9%)
Query: 295 LDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVR 354
LDF +H + M +K V + ++T ++SIGKS +G L+V+ + P EH +G PE +
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 355 YVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHR 414
YVA MHG+E +GRELLL L+ +L + +P +T L++ RIH++PSMNPDG+E
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Query: 415 GSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNAT 474
++ GR N DLN NF D + N +
Sbjct: 137 DCY---YSIGRENYNQYDLNRNFPDA---------------------------FEYNNVS 166
Query: 475 VAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDM-TRTPWAARELTPTPDDAVFRWLS 533
PET AV+KW+K FVLSANLHGG LV SYPFD + A + TPDD VF++L+
Sbjct: 167 RQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
Query: 534 TVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELS 593
YA N M+ C ++ + + NG W+ + G M D++Y+ CFE+T+ELS
Sbjct: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 594 CDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINH--D 651
C K+P E +LP W NNK +L+ Y++QV +G+ G V D++ + + ++ V H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN-PLPNVIVEVQDRKHICP 342
Query: 652 VTTAWGGDYWRLLTPGDYMVTASAEGY 678
T G+Y+ LL PG Y++ + G+
Sbjct: 343 YRTNKYGEYYLLLLPGSYIINVTVPGH 369
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 249 bits (636), Expect = 6e-66
Identities = 142/387 (36%), Positives = 211/387 (54%), Gaps = 38/387 (9%)
Query: 295 LDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVR 354
LDF +H + M +K V + ++T ++SIGKS +G L+V+ + P EH +G PE +
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 355 YVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHR 414
YVA MHG+E +GRELLL L+ +L + +P +T L++ RIH++PSMNPDG+E
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Query: 415 GSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNAT 474
++ GR N DLN NF D + N +
Sbjct: 137 DCY---YSIGRENYNQYDLNRNFPDA---------------------------FEYNNVS 166
Query: 475 VAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDM-TRTPWAARELTPTPDDAVFRWLS 533
PET AV+KW+K FVLSANLHGG LV SYPFD + A + TPDD VF++L+
Sbjct: 167 RQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
Query: 534 TVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELS 593
YA N M+ C ++ + + NG W+ + G M D++Y+ CFE+T+ELS
Sbjct: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 594 CDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINH--D 651
C K+P E +LP W NNK +L+ Y++QV +G+ G V D++ + + ++ V H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN-PLPNVIVEVQDRKHICP 342
Query: 652 VTTAWGGDYWRLLTPGDYMVTASAEGY 678
T G+Y+ LL PG Y++ + G+
Sbjct: 343 YRTNKYGEYYLLLLPGSYIINVTVPGH 369
>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
sapiens]
Length = 387
Score = 96.3 bits (238), Expect = 9e-20
Identities = 60/168 (35%), Positives = 81/168 (48%), Gaps = 16/168 (9%)
Query: 114 GCP-PLGLESLRVSDSRLEASSSQS------FGLGPHRGRLNIQSGLEDGDLYDGAWCAE 166
GC PLGL++ + D ++ ASSS F P RL+ Q AW A
Sbjct: 229 GCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFN-------AWVAG 281
Query: 167 EQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMD 226
D W QVD G +G+ITQG + +V SYKV +SNDS W ++ +G
Sbjct: 282 SYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSS 341
Query: 227 AVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILAC 274
+FP N D + NL P +AR++R+LP W A LR E+L C
Sbjct: 342 KIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIA--LRLELLGC 387
Score = 59.3 bits (142), Expect = 1e-08
Identities = 49/172 (28%), Positives = 86/172 (50%), Gaps = 16/172 (9%)
Query: 112 ETGC-PPLGLESLRVSDSRLEASSSQSFGLG-----PHRGRLNIQSGLEDGDLYDGAWCA 165
ET C PLGLE+ +++S++ ASS + LG P RLN ++G+ + AW
Sbjct: 67 ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLN-RAGMVN------AWTP 119
Query: 166 EEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGM 225
D +PW QV+ +GV+TQG + + ++++ ++KV +S + + + +
Sbjct: 120 SSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHE-FDFIHDVNKK 178
Query: 226 DAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVS 277
F N + +NL P A+++RL P + A LR E+L C ++
Sbjct: 179 HKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSC--HTACTLRFELLGCELN 228
>gi|31317224 EGF-like repeats and discoidin I-like
domains-containing protein 3 [Homo sapiens]
Length = 480
Score = 93.2 bits (230), Expect = 8e-19
Identities = 60/166 (36%), Positives = 87/166 (52%), Gaps = 14/166 (8%)
Query: 117 PLGLESLRVSDSRLEASSSQS--FGLG---PHRGRLNIQSGLEDGDLYDGAWCAEEQDAD 171
PLG+E +S+ ++ ASS+ FGL P+ RLN + GL + AW A E D
Sbjct: 161 PLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLN-KKGLIN------AWTAAENDRW 213
Query: 172 PWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPA 231
PW Q++ R +GVITQG + +++ SYK+ +SND +TW + + D VF
Sbjct: 214 PWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRG 273
Query: 232 NSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVS 277
N D TP N P A+++RL PQ + LR E+L C +S
Sbjct: 274 NIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCT--LRMELLGCELS 317
Score = 92.4 bits (228), Expect = 1e-18
Identities = 58/169 (34%), Positives = 83/169 (49%), Gaps = 16/169 (9%)
Query: 113 TGCP-PLGLESLRVSDSRLEASS------SQSFGLGPHRGRLNIQSGLEDGDLYDGAWCA 165
+GC PLG++S + D ++ ASS F P + RL+ Q + AW +
Sbjct: 317 SGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVN-------AWTS 369
Query: 166 EEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGM 225
D W QVD PT+ +G+ITQG +V SYK+ +SND W ++
Sbjct: 370 GHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRK 429
Query: 226 DAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILAC 274
D VF N D +T N++ P AR IR+LP +W G LR+E+L C
Sbjct: 430 DKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWY--GRITLRSELLGC 476
>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
sapiens]
Length = 224
Score = 87.4 bits (215), Expect = 4e-17
Identities = 57/168 (33%), Positives = 84/168 (50%), Gaps = 19/168 (11%)
Query: 115 CP---PLGLESLRVSDSRLEASSSQSF-----GLGPHRGRLNIQSGLEDGDLYDGAWCAE 166
CP PLG ES V+ ++ S+ + + ++ RLN Q + AW ++
Sbjct: 63 CPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQG-------FGCAWLSK 115
Query: 167 EQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMD 226
QD+ W Q+D SG++TQGR + +W+T Y VQ+ D R W +G +
Sbjct: 116 FQDSSQWLQIDLKEIKVISGILTQGRCDI--DEWMTKYSVQYRTDERLNWIYYKDQTGNN 173
Query: 227 AVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILAC 274
VF NSD + V NLL P ++RFIRL+P W A +R E+L C
Sbjct: 174 RVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIA--IRMELLEC 219
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 85.9 bits (211), Expect = 1e-16
Identities = 58/198 (29%), Positives = 94/198 (47%), Gaps = 19/198 (9%)
Query: 89 PLVTAGPLVTPTPAGTLDPAEKQETGCP------PLGLESLRVSDSRLEASSSQSFGLG- 141
P+V ++PT A + GC PLG+E+ ++ + ++ ASS + G
Sbjct: 2035 PIVARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGD 2094
Query: 142 ---PHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGVITQGRNSVWRY 198
P R RLN Q + AW A+ + W ++D + + +ITQG S+
Sbjct: 2095 YWEPFRARLNAQGRVN-------AWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSE 2147
Query: 199 DWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQT 258
+V SY + +S W R SS +D +F N++ + V N P ++RFIR++P+T
Sbjct: 2148 MYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKT 2207
Query: 259 WLQGGAPCLRAEILACPV 276
W Q A LR E+ C +
Sbjct: 2208 WNQSIA--LRLELFGCDI 2223
Score = 66.2 bits (160), Expect = 1e-10
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 14/165 (8%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDAD----P 172
P+GL + +SDS+++AS + P RLN +G Y+ AW E+ A+ P
Sbjct: 1910 PMGLSTGIISDSQIKASEFLGYW-EPRLARLN------NGGSYN-AWSVEKLAAEFASKP 1961
Query: 173 WFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPAN 232
W QVD +G+ TQG + + T + V +S++ W + +S+ F N
Sbjct: 1962 WIQVDMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGN 2021
Query: 233 SDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVS 277
SD T N P VAR+IR+ P P LR E+ C V+
Sbjct: 2022 SDASTIKENQFDPPIVARYIRISPTR--AYNRPTLRLELQGCEVN 2064
>gi|10518506 coagulation factor VIII isoform b precursor [Homo
sapiens]
Length = 216
Score = 82.4 bits (202), Expect = 1e-15
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 14/165 (8%)
Query: 117 PLGLESLRVSDSRLEASS--SQSFGL-GPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPW 173
PLG+ES +SD+++ ASS + F P + RL++Q AW + + W
Sbjct: 61 PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGR-------SNAWRPQVNNPKEW 113
Query: 174 FQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
QVD + +GV TQG S+ +V + + S D W + +G VF N
Sbjct: 114 LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQW--TLFFQNGKVKVFQGNQ 171
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D TPV+N L P + R++R+ PQ+W+ A LR E+L C D
Sbjct: 172 DSFTPVVNSLDPPLLTRYLRIHPQSWVHQIA--LRMEVLGCEAQD 214
>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
Length = 2351
Score = 82.4 bits (202), Expect = 1e-15
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 14/165 (8%)
Query: 117 PLGLESLRVSDSRLEASS--SQSFGL-GPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPW 173
PLG+ES +SD+++ ASS + F P + RL++Q AW + + W
Sbjct: 2196 PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGR-------SNAWRPQVNNPKEW 2248
Query: 174 FQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
QVD + +GV TQG S+ +V + + S D W + +G VF N
Sbjct: 2249 LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQW--TLFFQNGKVKVFQGNQ 2306
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D TPV+N L P + R++R+ PQ+W+ A LR E+L C D
Sbjct: 2307 DSFTPVVNSLDPPLLTRYLRIHPQSWVHQIA--LRMEVLGCEAQD 2349
Score = 57.4 bits (137), Expect = 5e-08
Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 12/161 (7%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQV 176
PLG+ S + D ++ AS Q P RL+ + AW +E + W +V
Sbjct: 2043 PLGMASGHIRDFQITASG-QYGQWAPKLARLHYSGSIN-------AWSTKEPFS--WIKV 2092
Query: 177 DAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPE 236
D P G+ TQG + +++ + + +S D + W R +S+G VF N D
Sbjct: 2093 DLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSS 2152
Query: 237 TPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVS 277
N+ P +AR+IRL P + LR E++ C ++
Sbjct: 2153 GIKHNIFNPPIIARYIRLHPTHY--SIRSTLRMELMGCDLN 2191
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 78.6 bits (192), Expect = 2e-14
Identities = 58/165 (35%), Positives = 83/165 (50%), Gaps = 16/165 (9%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLG-PHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQ 175
PLG+ES R+++ ++ ASS+ S G P + RL+ GD D W + Q
Sbjct: 280 PLGMESGRIANEQISASSTYSDGRWTPQQSRLH-------GD--DNGWTPNLDSNKEYLQ 330
Query: 176 VDAGHPTRFSGVITQGRNSVWRYD--WVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
VD T + + TQG S + +V SYK++ S + W R+ + VF AN+
Sbjct: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKN--HKVFQANN 388
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D VLN L P + RF+R+ PQTW G A LR E+ C V+D
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIA--LRLELFGCRVTD 431
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 22/171 (12%)
Query: 118 LGLESLRVSDSRLEASSSQSFGLGPHRGRL-NIQSGLEDGDLYDGAWCAEEQDADP---W 173
LG+ S ++DS++ ASS+Q + P RL + +SG W A P W
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSG----------WFPRIPQAQPGEEW 487
Query: 174 FQVDAGHPTRFSGVITQGR------NSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDA 227
QVD G P GVI QG +V +V +KV +S + + W ++ +
Sbjct: 488 LQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
Query: 228 VFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
+F N +TP + +P A+++R+ P+ W G +R E+L C +D
Sbjct: 548 LFEGNMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIG-MRLEVLGCDWTD 596
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 78.6 bits (192), Expect = 2e-14
Identities = 58/165 (35%), Positives = 83/165 (50%), Gaps = 16/165 (9%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLG-PHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQ 175
PLG+ES R+++ ++ ASS+ S G P + RL+ GD D W + Q
Sbjct: 280 PLGMESGRIANEQISASSTYSDGRWTPQQSRLH-------GD--DNGWTPNLDSNKEYLQ 330
Query: 176 VDAGHPTRFSGVITQGRNSVWRYD--WVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
VD T + + TQG S + +V SYK++ S + W R+ + VF AN+
Sbjct: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKN--HKVFQANN 388
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D VLN L P + RF+R+ PQTW G A LR E+ C V+D
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIA--LRLELFGCRVTD 431
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 22/171 (12%)
Query: 118 LGLESLRVSDSRLEASSSQSFGLGPHRGRL-NIQSGLEDGDLYDGAWCAEEQDADP---W 173
LG+ S ++DS++ ASS+Q + P RL + +SG W A P W
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSG----------WFPRIPQAQPGEEW 487
Query: 174 FQVDAGHPTRFSGVITQGR------NSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDA 227
QVD G P GVI QG +V +V +KV +S + + W ++ +
Sbjct: 488 LQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
Query: 228 VFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
+F N +TP + +P A+++R+ P+ W G +R E+L C +D
Sbjct: 548 LFEGNMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIG-MRLEVLGCDWTD 596
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 78.6 bits (192), Expect = 2e-14
Identities = 58/165 (35%), Positives = 83/165 (50%), Gaps = 16/165 (9%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLG-PHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQ 175
PLG+ES R+++ ++ ASS+ S G P + RL+ GD D W + Q
Sbjct: 280 PLGMESGRIANEQISASSTYSDGRWTPQQSRLH-------GD--DNGWTPNLDSNKEYLQ 330
Query: 176 VDAGHPTRFSGVITQGRNSVWRYD--WVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
VD T + + TQG S + +V SYK++ S + W R+ + VF AN+
Sbjct: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKN--HKVFQANN 388
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D VLN L P + RF+R+ PQTW G A LR E+ C V+D
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIA--LRLELFGCRVTD 431
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 22/171 (12%)
Query: 118 LGLESLRVSDSRLEASSSQSFGLGPHRGRL-NIQSGLEDGDLYDGAWCAEEQDADP---W 173
LG+ S ++DS++ ASS+Q + P RL + +SG W A P W
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSG----------WFPRIPQAQPGEEW 487
Query: 174 FQVDAGHPTRFSGVITQGR------NSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDA 227
QVD G P GVI QG +V +V +KV +S + + W ++ +
Sbjct: 488 LQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
Query: 228 VFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
+F N +TP + +P A+++R+ P+ W G +R E+L C +D
Sbjct: 548 LFEGNMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIG-MRLEVLGCDWTD 596
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 78.6 bits (192), Expect = 2e-14
Identities = 58/165 (35%), Positives = 83/165 (50%), Gaps = 16/165 (9%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLG-PHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQ 175
PLG+ES R+++ ++ ASS+ S G P + RL+ GD D W + Q
Sbjct: 280 PLGMESGRIANEQISASSTYSDGRWTPQQSRLH-------GD--DNGWTPNLDSNKEYLQ 330
Query: 176 VDAGHPTRFSGVITQGRNSVWRYD--WVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
VD T + + TQG S + +V SYK++ S + W R+ + VF AN+
Sbjct: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKN--HKVFQANN 388
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D VLN L P + RF+R+ PQTW G A LR E+ C V+D
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIA--LRLELFGCRVTD 431
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 20/108 (18%)
Query: 118 LGLESLRVSDSRLEASSSQSFGLGPHRGRL-NIQSGLEDGDLYDGAWCAEEQDADP---W 173
LG+ S ++DS++ ASS+Q + P RL + +SG W A P W
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSG----------WFPRIPQAQPGEEW 487
Query: 174 FQVDAGHPTRFSGVITQGR------NSVWRYDWVTSYKVQFSNDSRTW 215
QVD G P GVI QG +V +V +KV +S + + W
Sbjct: 488 LQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDW 535
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 78.6 bits (192), Expect = 2e-14
Identities = 58/165 (35%), Positives = 83/165 (50%), Gaps = 16/165 (9%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLG-PHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQ 175
PLG+ES R+++ ++ ASS+ S G P + RL+ GD D W + Q
Sbjct: 280 PLGMESGRIANEQISASSTYSDGRWTPQQSRLH-------GD--DNGWTPNLDSNKEYLQ 330
Query: 176 VDAGHPTRFSGVITQGRNSVWRYD--WVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
VD T + + TQG S + +V SYK++ S + W R+ + VF AN+
Sbjct: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKN--HKVFQANN 388
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D VLN L P + RF+R+ PQTW G A LR E+ C V+D
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIA--LRLELFGCRVTD 431
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 22/171 (12%)
Query: 118 LGLESLRVSDSRLEASSSQSFGLGPHRGRL-NIQSGLEDGDLYDGAWCAEEQDADP---W 173
LG+ S ++DS++ ASS+Q + P RL + +SG W A P W
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSG----------WFPRIPQAQPGEEW 487
Query: 174 FQVDAGHPTRFSGVITQGR------NSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDA 227
QVD G P GVI QG +V +V +KV +S + + W ++ +
Sbjct: 488 LQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
Query: 228 VFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
+F N +TP + +P A+++R+ P+ W G +R E+L C +D
Sbjct: 548 LFEGNMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIG-MRLEVLGCDWTD 596
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 78.6 bits (192), Expect = 2e-14
Identities = 58/165 (35%), Positives = 83/165 (50%), Gaps = 16/165 (9%)
Query: 117 PLGLESLRVSDSRLEASSSQSFGLG-PHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQ 175
PLG+ES R+++ ++ ASS+ S G P + RL+ GD D W + Q
Sbjct: 280 PLGMESGRIANEQISASSTYSDGRWTPQQSRLH-------GD--DNGWTPNLDSNKEYLQ 330
Query: 176 VDAGHPTRFSGVITQGRNSVWRYD--WVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANS 233
VD T + + TQG S + +V SYK++ S + W R+ + VF AN+
Sbjct: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKN--HKVFQANN 388
Query: 234 DPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
D VLN L P + RF+R+ PQTW G A LR E+ C V+D
Sbjct: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIA--LRLELFGCRVTD 431
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 22/171 (12%)
Query: 118 LGLESLRVSDSRLEASSSQSFGLGPHRGRL-NIQSGLEDGDLYDGAWCAEEQDADP---W 173
LG+ S ++DS++ ASS+Q + P RL + +SG W A P W
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSG----------WFPRIPQAQPGEEW 487
Query: 174 FQVDAGHPTRFSGVITQGR------NSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDA 227
QVD G P GVI QG +V +V +KV +S + + W ++ +
Sbjct: 488 LQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
Query: 228 VFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
+F N +TP + +P A+++R+ P+ W G +R E+L C +D
Sbjct: 548 LFEGNMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIG-MRLEVLGCDWTD 596
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
sapiens]
Length = 1331
Score = 78.6 bits (192), Expect = 2e-14
Identities = 47/143 (32%), Positives = 68/143 (47%), Gaps = 11/143 (7%)
Query: 132 ASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGVITQG 191
+SSS S P ++N + G G W + D W QVD G+ + S + TQG
Sbjct: 50 SSSSISGSYSPGYAKINKRGGA-------GGWSPSDSDHYQWLQVDFGNRKQISAIATQG 102
Query: 192 RNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQVARF 251
R S DWVT Y++ +S+ R W H G FP N + + V + L P +AR+
Sbjct: 103 RYS--SSDWVTQYRMLYSDTGRNW--KPYHQDGNIWAFPGNINSDGVVRHELQHPIIARY 158
Query: 252 IRLLPQTWLQGGAPCLRAEILAC 274
+R++P W G LR E+ C
Sbjct: 159 VRIVPLDWNGEGRIGLRIEVYGC 181
>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
sapiens]
Length = 775
Score = 73.9 bits (180), Expect = 5e-13
Identities = 56/186 (30%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Query: 113 TGC-PPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGA-WCAEEQDA 170
+GC LG+ES ++D ++ ASS + H G+ N + G W A D
Sbjct: 290 SGCYGTLGMESGVIADPQITASSVLEWT--DHTGQENSWKPKKARLKKPGPPWAAFATDE 347
Query: 171 DPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFP 230
W Q+D + +G+IT G V +V++Y++ +S+D + W R D +F
Sbjct: 348 YQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQ 407
Query: 231 ANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILAC---PVSDPNDLFLEAP 287
N D V N P +ARFIR+ P W Q A ++ E+L C P P L P
Sbjct: 408 GNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIA--MKMELLGCQFIPKGRPPKLTQPPP 465
Query: 288 ASGSSD 293
S+D
Sbjct: 466 PRNSND 471
>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
[Homo sapiens]
Length = 1207
Score = 71.6 bits (174), Expect = 2e-12
Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 11/147 (7%)
Query: 128 SRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGV 187
S +SS S GP RLN + G G W + W Q+D G + V
Sbjct: 42 SSFSSSSELSSSHGPGFSRLNRRDGA-------GGWTPLVSNKYQWLQIDLGERMEVTAV 94
Query: 188 ITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQ 247
TQG DWVTSY + FS+ R W R S FP N++ ++ V L P
Sbjct: 95 ATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWG--FPGNTNADSVVHYRLQPPF 150
Query: 248 VARFIRLLPQTWLQGGAPCLRAEILAC 274
ARF+R LP W G +R E+ C
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGC 177
>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
[Homo sapiens]
Length = 1288
Score = 71.6 bits (174), Expect = 2e-12
Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 11/147 (7%)
Query: 128 SRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGV 187
S +SS S GP RLN + G G W + W Q+D G + V
Sbjct: 42 SSFSSSSELSSSHGPGFSRLNRRDGA-------GGWTPLVSNKYQWLQIDLGERMEVTAV 94
Query: 188 ITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQ 247
TQG DWVTSY + FS+ R W R S FP N++ ++ V L P
Sbjct: 95 ATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWG--FPGNTNADSVVHYRLQPPF 150
Query: 248 VARFIRLLPQTWLQGGAPCLRAEILAC 274
ARF+R LP W G +R E+ C
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGC 177
>gi|239743729 PREDICTED: similar to contactin associated
protein-like 3B [Homo sapiens]
Length = 380
Score = 71.6 bits (174), Expect = 2e-12
Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 11/147 (7%)
Query: 128 SRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGV 187
S +SS S GP RLN + G G W + W Q+D G + V
Sbjct: 42 SSFSSSSELSSSHGPGFSRLNRRDGA-------GGWTPLVSNKYQWLQIDLGERMEVTAV 94
Query: 188 ITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQ 247
TQG DWVTSY + FS+ R W R S FP N++ ++ V L P
Sbjct: 95 ATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWG--FPGNTNADSVVHYRLQPPF 150
Query: 248 VARFIRLLPQTWLQGGAPCLRAEILAC 274
ARF+R LP W G +R E+ C
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGC 177
>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
Length = 1288
Score = 71.6 bits (174), Expect = 2e-12
Identities = 49/147 (33%), Positives = 63/147 (42%), Gaps = 11/147 (7%)
Query: 128 SRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGV 187
S +SS S GP RLN + G G W + W Q+D G + V
Sbjct: 42 SSFSSSSELSSSHGPGFSRLNRRDGA-------GGWTPLVSNKYQWLQIDLGERMEVTAV 94
Query: 188 ITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQ 247
TQG DWVTSY + FS+ R W R S FP N++ ++ V L P
Sbjct: 95 ATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWG--FPGNTNADSVVHYRLQPPF 150
Query: 248 VARFIRLLPQTWLQGGAPCLRAEILAC 274
ARF+R LP W G +R E+ C
Sbjct: 151 EARFLRFLPLAWNPRGRIGMRIEVYGC 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,391,674
Number of Sequences: 37866
Number of extensions: 1657009
Number of successful extensions: 5838
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 5551
Number of HSP's gapped (non-prelim): 230
length of query: 734
length of database: 18,247,518
effective HSP length: 110
effective length of query: 624
effective length of database: 14,082,258
effective search space: 8787328992
effective search space used: 8787328992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.