Search of human proteins with 9506689

Search of human proteins with 9506689

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9506689 exosome component 4 [Homo sapiens]
         (245 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9506689 exosome component 4 [Homo sapiens]                         480   e-136
gi|17402904 homolog of yeast mRNA transport regulator 3 [Homo sa...   107   1e-23
gi|47174864 exosome component Rrp46 [Homo sapiens]                     88   6e-18
gi|187282992 hypothetical protein LOC392145 [Homo sapiens]             58   9e-09
gi|188528628 polyribonucleotide nucleotidyltransferase 1 [Homo s...    47   2e-05
gi|31415882 exosome component 8 [Homo sapiens]                         36   0.035
gi|27436927 synoviolin 1 isoform b [Homo sapiens]                      33   0.23 
gi|27436925 synoviolin 1 isoform a [Homo sapiens]                      33   0.23 
gi|158634472 ADP-ribosyltransferase 1 [Homo sapiens]                   32   0.66 
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]             28   5.6  
gi|189083688 exosome component 7 [Homo sapiens]                        28   5.6  
gi|116235474 LKB1 interacting protein [Homo sapiens]                   28   7.3  
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]                 28   9.5  
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]                 28   9.5  
gi|157311635 FAM83H [Homo sapiens]                                     28   9.5  

>gi|9506689 exosome component 4 [Homo sapiens]
          Length = 245

 Score =  480 bits (1235), Expect = e-136
 Identities = 245/245 (100%), Positives = 245/245 (100%)

Query: 1   MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRG 60
           MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRG
Sbjct: 1   MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRG 60

Query: 61  SRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQ 120
           SRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQ
Sbjct: 61  SRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQ 120

Query: 121 IDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAA 180
           IDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAA
Sbjct: 121 IDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAA 180

Query: 181 GGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVREAS 240
           GGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVREAS
Sbjct: 181 GGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVREAS 240

Query: 241 ILLGD 245
           ILLGD
Sbjct: 241 ILLGD 245


>gi|17402904 homolog of yeast mRNA transport regulator 3 [Homo
           sapiens]
          Length = 272

 Score =  107 bits (266), Expect = 1e-23
 Identities = 65/189 (34%), Positives = 94/189 (49%), Gaps = 14/189 (7%)

Query: 22  LRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPD----------RAL 71
           LR + AR G+ +QA GSAY+E G TK L  V GP +  G      P           R  
Sbjct: 36  LRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGR 95

Query: 72  VNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQIDIYVQVLQAD 131
           + C +  A F+ G R+R P G  +  E+ L L++  E A+    +PR+Q+++   +L+  
Sbjct: 96  LLCDFRRAPFA-GRRRRAPPGGCEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDG 154

Query: 132 GGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTA---LADLSHVEEAAGGPQLALA 188
           G   AA + AA LA+ DAG+ M D V  C      G A   L D + +EE      L +A
Sbjct: 155 GSALAAALTAAALALADAGVEMYDLVVGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVA 214

Query: 189 LLPASGQIA 197
           L+P   Q+A
Sbjct: 215 LMPVLNQVA 223


>gi|47174864 exosome component Rrp46 [Homo sapiens]
          Length = 235

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 64/206 (31%), Positives = 97/206 (47%), Gaps = 16/206 (7%)

Query: 22  LRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVNCQYSSATF 81
           LR       + ++ DGSA   QG+T  LA VYGP E++ S+             ++ AT 
Sbjct: 28  LRHFACEQNLLSRPDGSASFLQGDTSVLAGVYGPAEVKVSKEI-----------FNKATL 76

Query: 82  STGERKR--RPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQIDIYVQVLQADGGTYAACV 139
               R +   P    KS E    +R T EA +L  LHPR+ I + +QV+   G   A C+
Sbjct: 77  EVILRPKIGLPGVAEKSRER--LIRNTCEAVVLGTLHPRTSITVVLQVVSDAGSLLACCL 134

Query: 140 NAATLAVLDAGIPMRDFVCACSAGF-VDGTALADLSHVEEAAGGPQLALALLPASGQIAL 198
           NAA +A++DAG+PMR   C  +     DGT + D +  +E      L  AL     ++ +
Sbjct: 135 NAACMALVDAGVPMRALFCGVACALDSDGTLVLDPTSKQEKEARAVLTFALDSVERKLLM 194

Query: 199 LEMDARLHEDHLERVLEAAAQAARDV 224
                   +  L++ L AA  A++ V
Sbjct: 195 SSTKGLYSDTELQQCLAAAQAASQHV 220


>gi|187282992 hypothetical protein LOC392145 [Homo sapiens]
          Length = 174

 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 3/116 (2%)

Query: 87  KRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQIDIYVQVLQADGGTYAACVNAATLAV 146
           +  P G  +  E  + L++  E A+    +P  Q++    +L+  G   A  +N A LA+
Sbjct: 52  RHAPTGGGEEPEPAMVLQEALEPAMCLDRYPHVQLEASELLLEDGGSALATELNTAKLAL 111

Query: 147 LDAGIPMRDFVCACSAGFVDG---TALADLSHVEEAAGGPQLALALLPASGQIALL 199
             AG+ M D V +C  G   G   T L D   +EE    P + LALLP   Q+A L
Sbjct: 112 AYAGMEMNDLVVSCGLGLAPGSVPTWLLDPMRLEEEHTAPGVTLALLPMLNQVARL 167


>gi|188528628 polyribonucleotide nucleotidyltransferase 1 [Homo
           sapiens]
          Length = 783

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 52/230 (22%), Positives = 93/230 (40%), Gaps = 29/230 (12%)

Query: 13  RVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRA-------RA 65
           R DGR    LR +   + +F    GSA  ++G T+ L  V       G ++         
Sbjct: 358 RCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFDSLESGIKSDQVITAING 417

Query: 66  LPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRS---QID 122
           + D+  +   Y    ++T E  +    +R+    G    +     I     PR     I 
Sbjct: 418 IKDKNFM-LHYEFPPYATNEIGKVTGLNRRELGHGALAEKALYPVI-----PRDFPFTIR 471

Query: 123 IYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFV-----------DGTALA 171
           +  +VL+++G +  A     +LA++D+G+P+   V   + G V           D   L 
Sbjct: 472 VTSEVLESNGSSSMASACGGSLALMDSGVPISSAVAGVAIGLVTKTDPEKGEIEDYRLLT 531

Query: 172 DLSHVEEAAGGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAA 221
           D+  +E+  G     +A    +  I  L+ D +L    ++ V+EA  QA+
Sbjct: 532 DILGIEDYNGDMDFKIA--GTNKGITALQADIKLPGIPIKIVMEAIQQAS 579


>gi|31415882 exosome component 8 [Homo sapiens]
          Length = 276

 Score = 35.8 bits (81), Expect = 0.035
 Identities = 17/40 (42%), Positives = 22/40 (55%)

Query: 13 RVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVV 52
          R DGR  GE R     +G  + ADGSA ++ GNT  +  V
Sbjct: 23 RPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGV 62


>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
          Length = 617

 Score = 33.1 bits (74), Expect = 0.23
 Identities = 17/45 (37%), Positives = 25/45 (55%)

Query: 190 LPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQ 234
           +P +G   L   + R  E H  + LEA  Q+ R++HTLLD  + Q
Sbjct: 476 VPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQ 520


>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
          Length = 616

 Score = 33.1 bits (74), Expect = 0.23
 Identities = 17/45 (37%), Positives = 25/45 (55%)

Query: 190 LPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQ 234
           +P +G   L   + R  E H  + LEA  Q+ R++HTLLD  + Q
Sbjct: 475 VPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQ 519


>gi|158634472 ADP-ribosyltransferase 1 [Homo sapiens]
          Length = 327

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 21/152 (13%)

Query: 110 AILTQLHPRSQIDIYVQVLQAD------GGTYAACVNAATLAVLDAGIPMRDFVCACSAG 163
           A+  Q HP ++ D++ Q +Q D         YA C  A T A+ D    +       +  
Sbjct: 19  ALQAQSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPD----LNHTEFQANQV 74

Query: 164 FVDGTALADLSHVEEAAGGPQLALALLPASGQ---------IALLEMDAR--LHEDHLER 212
           + D   LA     E  A  P+ +L+    S           +ALL   A   LH++    
Sbjct: 75  YADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAA 134

Query: 213 VLEAAAQAARDVHTLLDRVVRQHVREASILLG 244
           V EA    A  +H    + +   + EA  LLG
Sbjct: 135 VREAGRSRAHYLHHFSFKTLHFLLTEALQLLG 166


>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
          Length = 963

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 14/37 (37%), Positives = 19/37 (51%)

Query: 108 EAAILTQLHPRSQIDIYVQVLQADGGTYAACVNAATL 144
           E+  L + H   Q + YVQ    D  T+  C+N ATL
Sbjct: 100 ESWFLVEKHWYKQWEAYVQGGDQDSSTFPGCINNATL 136


>gi|189083688 exosome component 7 [Homo sapiens]
          Length = 291

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 12/148 (8%)

Query: 13  RVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALV 72
           RVDGR   + R ++    V +   GSA ++ G+T    ++ G     G+     P+   +
Sbjct: 23  RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTD---ILVGVKAEMGTPKLEKPNEGYL 79

Query: 73  NCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQL-----HPRSQ---IDIY 124
                 +  +T E + R  GD    E+   L + F       L      PR     + + 
Sbjct: 80  EFFVDCSASATPEFEGR-GGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVD 138

Query: 125 VQVLQADGGTYAACVNAATLAVLDAGIP 152
           V +L+  G  + A   A   A+ +  IP
Sbjct: 139 VLLLECGGNLFDAISIAVKAALFNTRIP 166


>gi|116235474 LKB1 interacting protein [Homo sapiens]
          Length = 1099

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 17/46 (36%), Positives = 22/46 (47%)

Query: 170 LADLSHVEEAAGGPQLALALLPASGQIALLEMDARLHEDHLERVLE 215
           L DLS +E    G  L L     +G+  LL  DAR     LE +L+
Sbjct: 872 LQDLSGIELGLAGQSLRLEWAAGAGRCVLLPRDARHCRAFLEELLD 917


>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
          Length = 2647

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 4/40 (10%)

Query: 26   QARMGVFAQADGSAYIE----QGNTKALAVVYGPHEIRGS 61
            +A+M      DGS  +E    +  T +L V YG H++ GS
Sbjct: 1397 EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGS 1436


>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
          Length = 2639

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 4/40 (10%)

Query: 26   QARMGVFAQADGSAYIE----QGNTKALAVVYGPHEIRGS 61
            +A+M      DGS  +E    +  T +L V YG H++ GS
Sbjct: 1397 EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGS 1436


>gi|157311635 FAM83H [Homo sapiens]
          Length = 1179

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%)

Query: 186 ALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQH 235
           A  ++ ++ Q+  + MD     D L  VLEAAA+    V+ LLD +  QH
Sbjct: 140 ARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRV-PVYILLDEMNAQH 188


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,520,253
Number of Sequences: 37866
Number of extensions: 349681
Number of successful extensions: 890
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 873
Number of HSP's gapped (non-prelim): 16
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.