BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|94536846 synaptotagmin VIII [Homo sapiens] (401 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|94536846 synaptotagmin VIII [Homo sapiens] 830 0.0 gi|211059429 synaptotagmin II [Homo sapiens] 295 6e-80 gi|31543670 synaptotagmin II [Homo sapiens] 295 6e-80 gi|209447073 synaptotagmin I [Homo sapiens] 283 1e-76 gi|5032139 synaptotagmin I [Homo sapiens] 283 1e-76 gi|209447070 synaptotagmin I [Homo sapiens] 283 1e-76 gi|92859638 synaptotagmin V [Homo sapiens] 280 2e-75 gi|39752671 synaptotagmin X [Homo sapiens] 171 1e-42 gi|45504376 synaptotagmin VI [Homo sapiens] 167 2e-41 gi|28376627 synaptotagmin IX [Homo sapiens] 166 5e-41 gi|38570146 synaptotagmin VII [Homo sapiens] 161 1e-39 gi|238550198 synaptotagmin III [Homo sapiens] 156 3e-38 gi|238550196 synaptotagmin III [Homo sapiens] 156 3e-38 gi|14150054 synaptotagmin III [Homo sapiens] 156 3e-38 gi|40068038 B/K protein [Homo sapiens] 143 2e-34 gi|24308219 synaptotagmin IV [Homo sapiens] 138 1e-32 gi|216548478 synaptotagmin XI [Homo sapiens] 127 2e-29 gi|29366828 synaptotagmin XII [Homo sapiens] 119 5e-27 gi|6005997 double C2-like domains, beta [Homo sapiens] 115 5e-26 gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 108 7e-24 gi|24308233 synaptotagmin XIII [Homo sapiens] 107 2e-23 gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 107 2e-23 gi|47078261 double C2-like domains, alpha [Homo sapiens] 96 4e-20 gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 96 6e-20 gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 96 6e-20 gi|193804862 synaptotagmin-like 4 [Homo sapiens] 92 8e-19 gi|193804860 synaptotagmin-like 4 [Homo sapiens] 92 8e-19 gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 92 8e-19 gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] 82 7e-16 gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens] 82 7e-16 >gi|94536846 synaptotagmin VIII [Homo sapiens] Length = 401 Score = 830 bits (2143), Expect = 0.0 Identities = 401/401 (100%), Positives = 401/401 (100%) Query: 1 MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGV 60 MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGV Sbjct: 1 MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGV 60 Query: 61 LLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGR 120 LLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGR Sbjct: 61 LLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGR 120 Query: 121 LQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFD 180 LQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFD Sbjct: 121 LQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFD 180 Query: 181 ETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAA 240 ETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAA Sbjct: 181 ETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAA 240 Query: 241 TQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATK 300 TQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATK Sbjct: 241 TQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATK 300 Query: 301 KGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWA 360 KGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWA Sbjct: 301 KGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWA 360 Query: 361 DMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS 401 DMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS Sbjct: 361 DMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS 401 >gi|211059429 synaptotagmin II [Homo sapiens] Length = 419 Score = 295 bits (754), Expect = 6e-80 Identities = 157/360 (43%), Positives = 229/360 (63%), Gaps = 21/360 (5%) Query: 45 PWPRWALIAGALAAGVLLVSCL--LCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQ 102 P P WALIA A+ AG+LL++C +C CCC ++ KK + K G+ +A Q Sbjct: 59 PLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGK---GMKNAMNMKDMKGGQ 115 Query: 103 PDVD---GLESSPGDAQQ------WGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTV 150 D D GL G+ ++ G+LQ SL++DF + ++ VG+ QAA+L GGT Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175 Query: 151 DPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGH 210 DPY +V + ++ETKVHR TL P F+ET F +P EL G TL + +++F RFS H Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235 Query: 211 EPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEAR 270 + +GE+++P+ TVDL +E W L +PE++G++C SLRYVP++G+LTV +LEA+ Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295 Query: 271 GLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDL 326 L+ GL++PYVK+ LM N ++ KK+KT KK T PYFNE+F+F +PF Q+Q V + Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355 Query: 327 VLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRML 386 V+ V D + E +GK+ +G+ A+G L+HW+DMLA+ RRPIAQ H L+P EVD +L Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415 >gi|31543670 synaptotagmin II [Homo sapiens] Length = 419 Score = 295 bits (754), Expect = 6e-80 Identities = 157/360 (43%), Positives = 229/360 (63%), Gaps = 21/360 (5%) Query: 45 PWPRWALIAGALAAGVLLVSCL--LCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQ 102 P P WALIA A+ AG+LL++C +C CCC ++ KK + K G+ +A Q Sbjct: 59 PLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGK---GMKNAMNMKDMKGGQ 115 Query: 103 PDVD---GLESSPGDAQQ------WGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTV 150 D D GL G+ ++ G+LQ SL++DF + ++ VG+ QAA+L GGT Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175 Query: 151 DPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGH 210 DPY +V + ++ETKVHR TL P F+ET F +P EL G TL + +++F RFS H Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235 Query: 211 EPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEAR 270 + +GE+++P+ TVDL +E W L +PE++G++C SLRYVP++G+LTV +LEA+ Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295 Query: 271 GLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDL 326 L+ GL++PYVK+ LM N ++ KK+KT KK T PYFNE+F+F +PF Q+Q V + Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355 Query: 327 VLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRML 386 V+ V D + E +GK+ +G+ A+G L+HW+DMLA+ RRPIAQ H L+P EVD +L Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415 >gi|209447073 synaptotagmin I [Homo sapiens] Length = 422 Score = 283 bits (725), Expect = 1e-76 Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%) Query: 45 PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97 P P WALIA A+ A +L+++C C C + + K + KE G + G T Sbjct: 55 PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114 Query: 98 THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146 D D GL + P + ++ G+LQ SL++DF + ++ VG+ QAA+L Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174 Query: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206 GGT DPY +V + + ETKVHR TL PVF+E F +P +EL G TL + +++F R Sbjct: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234 Query: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266 FS H+ +GE ++P+ TVD HV E W L + E++G++CFSLRYVP++G+LTVV+ Sbjct: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294 Query: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322 LEA+ L+ GL++PYVK+ LM N ++ KK+KT KK T PY+NE+F+F VPF Q+Q Sbjct: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354 Query: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382 V +V+ V D + + +GKV +G ++G L+HW+DMLA+ RRPIAQ H L+ EV Sbjct: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414 Query: 383 DRMLALQ 389 D MLA++ Sbjct: 415 DAMLAVK 421 >gi|5032139 synaptotagmin I [Homo sapiens] Length = 422 Score = 283 bits (725), Expect = 1e-76 Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%) Query: 45 PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97 P P WALIA A+ A +L+++C C C + + K + KE G + G T Sbjct: 55 PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114 Query: 98 THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146 D D GL + P + ++ G+LQ SL++DF + ++ VG+ QAA+L Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174 Query: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206 GGT DPY +V + + ETKVHR TL PVF+E F +P +EL G TL + +++F R Sbjct: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234 Query: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266 FS H+ +GE ++P+ TVD HV E W L + E++G++CFSLRYVP++G+LTVV+ Sbjct: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294 Query: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322 LEA+ L+ GL++PYVK+ LM N ++ KK+KT KK T PY+NE+F+F VPF Q+Q Sbjct: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354 Query: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382 V +V+ V D + + +GKV +G ++G L+HW+DMLA+ RRPIAQ H L+ EV Sbjct: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414 Query: 383 DRMLALQ 389 D MLA++ Sbjct: 415 DAMLAVK 421 >gi|209447070 synaptotagmin I [Homo sapiens] Length = 422 Score = 283 bits (725), Expect = 1e-76 Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%) Query: 45 PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97 P P WALIA A+ A +L+++C C C + + K + KE G + G T Sbjct: 55 PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114 Query: 98 THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146 D D GL + P + ++ G+LQ SL++DF + ++ VG+ QAA+L Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174 Query: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206 GGT DPY +V + + ETKVHR TL PVF+E F +P +EL G TL + +++F R Sbjct: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234 Query: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266 FS H+ +GE ++P+ TVD HV E W L + E++G++CFSLRYVP++G+LTVV+ Sbjct: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294 Query: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322 LEA+ L+ GL++PYVK+ LM N ++ KK+KT KK T PY+NE+F+F VPF Q+Q Sbjct: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354 Query: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382 V +V+ V D + + +GKV +G ++G L+HW+DMLA+ RRPIAQ H L+ EV Sbjct: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414 Query: 383 DRMLALQ 389 D MLA++ Sbjct: 415 DAMLAVK 421 >gi|92859638 synaptotagmin V [Homo sapiens] Length = 386 Score = 280 bits (715), Expect = 2e-75 Identities = 163/380 (42%), Positives = 227/380 (59%), Gaps = 21/380 (5%) Query: 22 PSAPAPAGTTAIPGLIPDL--VAGTPWPRWALIAGALAAGVLLVSCLLCAACCCCRRHR- 78 P P P + P PD ++ P P WAL L +G+L+ SC C CRR Sbjct: 3 PEPPTPGPPS--PDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG 60 Query: 79 KKPRDKESVGLGSARGTTTTHL--VQPDVDGLESSPG-------DAQQWGRLQLSLEFDF 129 KK + + V L +G +++ VQP+V+ LE +P D + GRLQ SL++DF Sbjct: 61 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF 120 Query: 130 GSQEIRVGLRQA---ADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH 186 S ++ VG+ QA A L GG+ DPY RV + R+ETKVHR TL P F ET F Sbjct: 121 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK 180 Query: 187 IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQV 246 +P EL G L + +++F RFS ++ +GE+R+P+ +VDL ++ W L + E++ Sbjct: 181 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL 240 Query: 247 GELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKG 302 G++CFSLRYVP++G+LTV+VLEA+ L+ GL++PYVKV L+ +K +K+KT KK Sbjct: 241 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN 300 Query: 303 TAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADM 362 T PY+NEAF+F VP QVQ V + L V D + E +G+V +GA A G L+HWADM Sbjct: 301 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM 360 Query: 363 LAHARRPIAQRHPLRPAREV 382 LA+ RRPIAQ H LRP V Sbjct: 361 LANPRRPIAQWHSLRPPDRV 380 >gi|39752671 synaptotagmin X [Homo sapiens] Length = 523 Score = 171 bits (432), Expect = 1e-42 Identities = 113/325 (34%), Positives = 164/325 (50%), Gaps = 24/325 (7%) Query: 75 RRHRKKPRDKESVGLGSA------RGTTTTHL--------VQPDVDGLESSPGDAQQWGR 120 RRH + SV RG TTT + Q VD + D + G+ Sbjct: 175 RRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGK 234 Query: 121 LQLSLEFDFGSQEIRVGLRQAADLRPG---GTVDPYARVSVSTQAGHRHETKVHRGTLCP 177 L +L++D+ ++ + V + +A DL GT DPY ++ + + +T+VHR TL P Sbjct: 235 LNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNP 294 Query: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLP--LGTVDLQHVLEHWYLL 235 +FDET F + +L L +++F RFS H+ +GE+ L DL W + Sbjct: 295 LFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDI 354 Query: 236 GPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRK 291 A T+ +GE+ FSL Y+P++GR+T+ V++ R L+ G ++PYVKV LM R+ Sbjct: 355 HC-ATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413 Query: 292 WKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARA 351 KKRKT TKK T P +NEA F +P V V L +AV D E +G G A Sbjct: 414 LKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDA 473 Query: 352 SGQPLQHWADMLAHARRPIAQRHPL 376 G HW +MLA+ R+PI HPL Sbjct: 474 EGLGRDHWNEMLAYHRKPITHWHPL 498 >gi|45504376 synaptotagmin VI [Homo sapiens] Length = 425 Score = 167 bits (423), Expect = 2e-41 Identities = 99/284 (34%), Positives = 154/284 (54%), Gaps = 10/284 (3%) Query: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRPG---GTVDPYARVSV 158 Q VDG ++ + G++ SL +D+ ++ + V + +A DL G+ DPY ++ + Sbjct: 129 QKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYL 188 Query: 159 STQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218 + +T+VHR TL P FDE F +P EL L + +F+F RFS H+ +GE+ L Sbjct: 189 LPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVIL 248 Query: 219 P--LGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274 DL W + A ++ +GE+ FSL Y+P++GRLT+ V++ R L+ Sbjct: 249 DNLFEASDLSRETSIWKDI-QYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMD 307 Query: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWD 332 G ++PYVKV L+ + R+ KK+KT KK T P +NEA F +P + V L+++V D Sbjct: 308 ITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMD 367 Query: 333 RSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376 E +G +G A G HW +MLA+ R+PIA H L Sbjct: 368 YDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411 >gi|28376627 synaptotagmin IX [Homo sapiens] Length = 491 Score = 166 bits (419), Expect = 5e-41 Identities = 97/284 (34%), Positives = 153/284 (53%), Gaps = 10/284 (3%) Query: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSV 158 Q +D + +++ G+L L++D +++ V + +A +L GT DPY ++ + Sbjct: 205 QRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYL 264 Query: 159 STQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218 +H+TKVHR TL PVFDE F +P +L L +++F RFS H+ +G++ + Sbjct: 265 LPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVV 324 Query: 219 P--LGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274 L D W + +GEL FSL Y+P++GRLT+ +++AR L+ Sbjct: 325 DHFLDLADFPRECILWKDI-EYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMD 383 Query: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWD 332 G ++PYVKV LM + R+ KKRKT+TK+ T P +NEA F VP + + L +AV D Sbjct: 384 ITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMD 443 Query: 333 RSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376 E +G +G A HW++ML++ R+PIA H L Sbjct: 444 YDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSL 487 >gi|38570146 synaptotagmin VII [Homo sapiens] Length = 403 Score = 161 bits (407), Expect = 1e-39 Identities = 98/309 (31%), Positives = 170/309 (55%), Gaps = 12/309 (3%) Query: 78 RKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQ-WGRLQLSLEFDFGSQEIRV 136 R +PR S + S T+ ++ P + E+ G +++ GR+Q S+ ++F + V Sbjct: 97 RTEPRSSVSDLVNSL--TSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTV 154 Query: 137 GLRQAADLRP---GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAEL 192 + +A +L GT DP+ ++ + H+ ETKV R L P ++ET F P ++ Sbjct: 155 KIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKV 214 Query: 193 PGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFS 252 L +Q+ ++ RFS ++P+GE+ +PL VDL + W L P + + GEL S Sbjct: 215 VQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSR-GELLLS 273 Query: 253 LRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYF 308 L Y PS+ + V +++AR L+ G ++PYVKV LM ++ +K+KT T K P F Sbjct: 274 LCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIF 333 Query: 309 NEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARR 368 NE+F F +P +++ +++ V D+ R + +GK++L ++ ++HW DM+A R+ Sbjct: 334 NESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQ 393 Query: 369 PIAQRHPLR 377 P+AQ H L+ Sbjct: 394 PVAQWHQLK 402 >gi|238550198 synaptotagmin III [Homo sapiens] Length = 590 Score = 156 bits (395), Expect = 3e-38 Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%) Query: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169 G GR+ +L + +GS ++ V + QA DL G DPY ++ + + +TK Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354 Query: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229 VHR TL PVF+ET F +P AEL L +++F RFS H+ +G+ V L ++L Sbjct: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407 Query: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275 E PP ++ +GEL FSL Y+P++GRLTV +++A L+ G Sbjct: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465 Query: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335 ++PYVK L+ R+ KKRKT+ KK T P +NEA F V V+NV L +AV D Sbjct: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525 Query: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376 E +G +G A+ +HWA+MLA+ R+P+ H L Sbjct: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567 >gi|238550196 synaptotagmin III [Homo sapiens] Length = 590 Score = 156 bits (395), Expect = 3e-38 Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%) Query: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169 G GR+ +L + +GS ++ V + QA DL G DPY ++ + + +TK Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354 Query: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229 VHR TL PVF+ET F +P AEL L +++F RFS H+ +G+ V L ++L Sbjct: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407 Query: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275 E PP ++ +GEL FSL Y+P++GRLTV +++A L+ G Sbjct: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465 Query: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335 ++PYVK L+ R+ KKRKT+ KK T P +NEA F V V+NV L +AV D Sbjct: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525 Query: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376 E +G +G A+ +HWA+MLA+ R+P+ H L Sbjct: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567 >gi|14150054 synaptotagmin III [Homo sapiens] Length = 590 Score = 156 bits (395), Expect = 3e-38 Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%) Query: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169 G GR+ +L + +GS ++ V + QA DL G DPY ++ + + +TK Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354 Query: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229 VHR TL PVF+ET F +P AEL L +++F RFS H+ +G+ V L ++L Sbjct: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407 Query: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275 E PP ++ +GEL FSL Y+P++GRLTV +++A L+ G Sbjct: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465 Query: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335 ++PYVK L+ R+ KKRKT+ KK T P +NEA F V V+NV L +AV D Sbjct: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525 Query: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376 E +G +G A+ +HWA+MLA+ R+P+ H L Sbjct: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567 >gi|40068038 B/K protein [Homo sapiens] Length = 474 Score = 143 bits (361), Expect = 2e-34 Identities = 96/298 (32%), Positives = 153/298 (51%), Gaps = 17/298 (5%) Query: 104 DVDGL-ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRPGGTVD----------P 152 DVD L + Q G L S ++D + V + +A DL P + D P Sbjct: 170 DVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNP 229 Query: 153 YARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEP 212 Y ++ + + +T V R T PVF+E F IP E TL + + +F +FS H Sbjct: 230 YVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCV 289 Query: 213 LGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGL 272 +G++ +PL VDL HW+ P++ ++GEL SL Y+PS+GRL V V+ A+ L Sbjct: 290 IGKVSVPLCEVDLVKG-GHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQL 348 Query: 273 RPGL----AEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVL 328 ++P+VK+QL+ + K +KT+ +GT P++NE+F+F VP +++N LV Sbjct: 349 LQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVF 408 Query: 329 AVWDRSLPLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPLRPAREVDRM 385 V+ ++ + +G++ +G +SG HW ML R + Q H LR E DR+ Sbjct: 409 TVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRV 466 >gi|24308219 synaptotagmin IV [Homo sapiens] Length = 425 Score = 138 bits (347), Expect = 1e-32 Identities = 98/305 (32%), Positives = 158/305 (51%), Gaps = 23/305 (7%) Query: 83 DKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAA 142 +KESV S + +T+ +S ++ G L SLE++F + V +++A Sbjct: 130 EKESVSPESLKSSTSL-----------TSEEKQEKLGTLFFSLEYNFERKAFVVNIKEAR 178 Query: 143 DL----RPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAELPGATL 197 L T DPY ++++ + H+ +T+V R TL P FDET F+ IP ++ L Sbjct: 179 GLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELAL 238 Query: 198 QVQLFNFKRFSGHEPLGELRLPLGTVDLQH--VLEHWYLLGPPAATQPEQVGELCFSLRY 255 + +F RFS + +GE+ +PL ++L +L + ++ + GEL SL Y Sbjct: 239 HFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGR-GELLISLCY 297 Query: 256 VPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEA 311 ++ LTVVVL+AR L GL++PYVKV L +++ K+KT KK T FNE Sbjct: 298 QSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNEL 357 Query: 312 FTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIA 371 F F +P ++++ + V D R E +G++ LGA A G +HW ++ + RR IA Sbjct: 358 FVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIA 417 Query: 372 QRHPL 376 + H L Sbjct: 418 KWHVL 422 >gi|216548478 synaptotagmin XI [Homo sapiens] Length = 431 Score = 127 bits (319), Expect = 2e-29 Identities = 94/288 (32%), Positives = 149/288 (51%), Gaps = 30/288 (10%) Query: 110 SSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADL-----RPGGTVDPYARVSVSTQAGH 164 SSP + G L S++++F + + V +++A L + G+ DPY ++++ H Sbjct: 150 SSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGS-DPYIKMTILPDKRH 208 Query: 165 RHETKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV 223 R +T+V R TL PVFDET F+ IP ++L L + +F RFS + +GE+ +PL V Sbjct: 209 RVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV 268 Query: 224 DLQHVLEHWYLLGPPAATQPE---------QVGELCFSLRYVPSSGRLTVVVLEARGLRP 274 D G T+ GEL SL Y P + R+TVVVL+AR L Sbjct: 269 DPS--------TGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPK 320 Query: 275 ----GLA-EPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLA 329 GL+ PYVKV + +++ K+KT KK T P FNE+F + +P + ++ + Sbjct: 321 MDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFL 380 Query: 330 VWDRSLPLRTEPVGKVHLGARA-SGQPLQHWADMLAHARRPIAQRHPL 376 V D + E VG++ LGA + + +HW ++ R+P+A+ H L Sbjct: 381 VIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428 >gi|29366828 synaptotagmin XII [Homo sapiens] Length = 421 Score = 119 bits (298), Expect = 5e-27 Identities = 83/266 (31%), Positives = 128/266 (48%), Gaps = 7/266 (2%) Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADL---RPGGTVDPYARVSVSTQAGHRHETKVHRGTL 175 G++++S+E+D S + V + Q DL + RVS+ +++ R Sbjct: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 Query: 176 CPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLL 235 FDE + L +L+ +F + G + L L +DL +L Sbjct: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLY 273 Query: 236 GPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGL----RPGLAEPYVKVQLMLNQRK 291 + VGE+ SL Y+P++ RLTVVV++A+ L A+P+VKV L+ + RK Sbjct: 274 LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRK 333 Query: 292 WKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARA 351 K+KTA K+ P FNEA F VP +Q++ L + V + S R + VG V +G A Sbjct: 334 MSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSA 393 Query: 352 SGQPLQHWADMLAHARRPIAQRHPLR 377 SG HW MLA RRP++ H +R Sbjct: 394 SGMGTTHWNQMLATLRRPVSMWHAVR 419 >gi|6005997 double C2-like domains, beta [Homo sapiens] Length = 412 Score = 115 bits (289), Expect = 5e-26 Identities = 86/291 (29%), Positives = 134/291 (46%), Gaps = 18/291 (6%) Query: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSV 158 +PD DG ES D G L SL +D + + + +A L+P G DPY ++ + Sbjct: 113 EPDADGYESD--DCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHL 170 Query: 159 STQAGHRHE--TKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGE 215 A ++ TK R TL P ++ET ++ I ++ TL++ + + +F +E +GE Sbjct: 171 LPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGE 230 Query: 216 LRLPLGTVDLQHV------LEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEA 269 R+PL + H LE + E+ G + SL+Y L V ++ Sbjct: 231 TRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRC 290 Query: 270 RGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVD 325 L G ++PYVK L + K K KTA KK T P FNE F + + + Sbjct: 291 AHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKS 350 Query: 326 LVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376 L + VWD + + +G V LG A G+ L+HW D L + + I + H L Sbjct: 351 LEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTL 401 >gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sapiens] Length = 431 Score = 108 bits (271), Expect = 7e-24 Identities = 87/301 (28%), Positives = 135/301 (44%), Gaps = 26/301 (8%) Query: 101 VQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--GGTVDPYARVSV 158 +QPD + E D+ G L+ +L F+ + + +A L+P G+ D Y + ++ Sbjct: 123 LQPDPEP-EGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANL 181 Query: 159 STQAGHRHETKVH--RGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEP--- 212 A + + H RGT PV++ET +H + + TL+ L + P Sbjct: 182 LPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQ 241 Query: 213 -------LGELRLPLGTV------DLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSS 259 LGELR+PL + LE L E+ G + SL Y Sbjct: 242 RQWQAPSLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQ 301 Query: 260 GRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL 315 G L V VL L P G ++P+V++ L N K K KT+ + T P FNE F + Sbjct: 302 GGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYS 361 Query: 316 VPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHP 375 P ++ L+++VWD L + +G V LG+ ASG+ L+HW + L H+ + HP Sbjct: 362 GPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHP 421 Query: 376 L 376 L Sbjct: 422 L 422 >gi|24308233 synaptotagmin XIII [Homo sapiens] Length = 426 Score = 107 bits (267), Expect = 2e-23 Identities = 86/287 (29%), Positives = 129/287 (44%), Gaps = 11/287 (3%) Query: 101 VQPDVDGLES-SPGDAQQWG---RLQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARV 156 V DV +E+ +P A W +L L++D E+ V +A G D Y + Sbjct: 138 VVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAVTSNHDGGCDCYVQG 197 Query: 157 SVSTQAGH-RHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGE 215 SV+ + G +T + + L ++E + + ELP ATL + L RFS H GE Sbjct: 198 SVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGE 257 Query: 216 LRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPG 275 LRL L + W L A GE+ S+ Y+P++ RL VV+++A+ L Sbjct: 258 LRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSN 317 Query: 276 LAEPY------VKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLA 329 ++ VKV L RK KK++T K P +NE F +P +Q + L Sbjct: 318 QSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELE 377 Query: 330 VWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376 V + ++ +G LG SG HW +ML + RR IA H L Sbjct: 378 VLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQL 424 >gi|31881675 synaptotagmin XV isoform a [Homo sapiens] Length = 421 Score = 107 bits (267), Expect = 2e-23 Identities = 78/269 (28%), Positives = 131/269 (48%), Gaps = 13/269 (4%) Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLR-PGGTVDPYARVSVSTQAGHRHETKVHRGTLCP 177 GRL S+E++ ++ + VGL +A L+ P T P ++ + ++K R T P Sbjct: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNP 208 Query: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV----DLQHVLEHWY 233 FDE F + + L+ +++ R H+ LG++ PL D + V+ W Sbjct: 209 QFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVI--WR 266 Query: 234 LLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQ 289 L + P + G+L F L Y RLTVVVL A+GLR G+ +VKV LM + Sbjct: 267 DLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHN 326 Query: 290 RKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLG- 348 + K +KT+ G+ P +NE F+F +++ L L V +++ +G+V +G Sbjct: 327 KFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP 386 Query: 349 -ARASGQPLQHWADMLAHARRPIAQRHPL 376 G+ L+HW +ML+ + + + H L Sbjct: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415 >gi|47078261 double C2-like domains, alpha [Homo sapiens] Length = 400 Score = 96.3 bits (238), Expect = 4e-20 Identities = 83/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (12%) Query: 104 DVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVST 160 +VD +S DA G L+ L +D S + + +A L+P G DPY ++ + Sbjct: 78 EVDSYDSD--DATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLP 135 Query: 161 QA--GHRHETKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELR 217 A ++ +TK R TL PV++E + I ++ L++ + + + S +E +GE+R Sbjct: 136 GACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIR 195 Query: 218 LPLGTV------DLQHVLEHWYLLGPPAATQP----------------------EQVGEL 249 +PL + LE L P++ E+ G + Sbjct: 196 VPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRI 255 Query: 250 CFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAA 305 SL Y L V +L L G ++PYVK L + K K KT KK T Sbjct: 256 LLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLN 315 Query: 306 PYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAH 365 P FNE F + + S + L + VWD + + +G V LG A G+ +HW+D L Sbjct: 316 PEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQ 375 Query: 366 ARRPIAQRHPL 376 + + H L Sbjct: 376 PDAALERWHTL 386 Score = 54.7 bits (130), Expect = 1e-07 Identities = 45/139 (32%), Positives = 65/139 (46%), Gaps = 23/139 (16%) Query: 235 LGPPAA----TQPEQ--------------VGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274 L PPAA T PE +G L F L Y +S L +L A+GL+P Sbjct: 61 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD 120 Query: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL-VPFSQVQNVDLVLAVW 331 GLA+PYVK+ L+ K K KT T++ T P +NE T+ + + + L +AV Sbjct: 121 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC 180 Query: 332 DRSLPLRTEPVGKVHLGAR 350 D E +G++ + R Sbjct: 181 DEDKLSHNEFIGEIRVPLR 199 Score = 42.7 bits (99), Expect = 6e-04 Identities = 41/157 (26%), Positives = 70/157 (44%), Gaps = 20/157 (12%) Query: 104 DVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVST 160 +++ E G ++ GR+ LSL + + + VG+ + A L G DPY + + Sbjct: 238 ELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRP 297 Query: 161 QAGHR--HETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218 + H+T V + TL P F+E + I + L TL+V ++++ ++ +G + L Sbjct: 298 DVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSL 357 Query: 219 PLGTVD---------LQH---VLEHWYLLG---PPAA 240 G LQ LE W+ L PPAA Sbjct: 358 GPGARGEARKHWSDCLQQPDAALERWHTLTSELPPAA 394 >gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] Length = 694 Score = 95.9 bits (237), Expect = 6e-20 Identities = 80/303 (26%), Positives = 135/303 (44%), Gaps = 34/303 (11%) Query: 114 DAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--T 168 +A G L+ SL +D + ++ + +A L+P G DPY ++ + A ++ T Sbjct: 389 EATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRT 448 Query: 169 KVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV---- 223 K R T P+++ET +H I ++ TL++ + + +F +E +GE R L + Sbjct: 449 KTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQ 508 Query: 224 --DLQHVLEHWYLLGPPAAT---------QPEQV---------GELCFSLRYVPSSGRLT 263 + LE + T + EQV G++ SL Y G L Sbjct: 509 RKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLI 568 Query: 264 VVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFS 319 V ++ L G ++P+VK+ L + K K KT KK T P FNE F + + S Sbjct: 569 VGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHS 628 Query: 320 QVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPA 379 + L ++VWD + + +G LG A G+ L+HW + L + + I + H L+ Sbjct: 629 DLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNE 688 Query: 380 REV 382 V Sbjct: 689 NHV 691 Score = 44.3 bits (103), Expect = 2e-04 Identities = 34/149 (22%), Positives = 70/149 (46%), Gaps = 13/149 (8%) Query: 90 GSARGTTTTHLVQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146 GSARG Q + GD ++ G++ +SL + + VG+ + L Sbjct: 529 GSARGMALYEEEQVE------RVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDA 582 Query: 147 GGTVDPYARVSVSTQAGHR--HETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNF 204 G DP+ ++ + G + H+T++ + TL P F+E + I ++L +L + ++++ Sbjct: 583 NGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDY 642 Query: 205 KRFSGHEPLGELRLPLGTVDLQHVLEHWY 233 ++ +G +L + + L+HWY Sbjct: 643 DIGKSNDYIGGCQLGISAKGER--LKHWY 669 >gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] Length = 690 Score = 95.9 bits (237), Expect = 6e-20 Identities = 80/303 (26%), Positives = 135/303 (44%), Gaps = 34/303 (11%) Query: 114 DAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--T 168 +A G L+ SL +D + ++ + +A L+P G DPY ++ + A ++ T Sbjct: 385 EATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRT 444 Query: 169 KVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV---- 223 K R T P+++ET +H I ++ TL++ + + +F +E +GE R L + Sbjct: 445 KTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQ 504 Query: 224 --DLQHVLEHWYLLGPPAAT---------QPEQV---------GELCFSLRYVPSSGRLT 263 + LE + T + EQV G++ SL Y G L Sbjct: 505 RKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLI 564 Query: 264 VVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFS 319 V ++ L G ++P+VK+ L + K K KT KK T P FNE F + + S Sbjct: 565 VGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHS 624 Query: 320 QVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPA 379 + L ++VWD + + +G LG A G+ L+HW + L + + I + H L+ Sbjct: 625 DLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNE 684 Query: 380 REV 382 V Sbjct: 685 NHV 687 Score = 44.3 bits (103), Expect = 2e-04 Identities = 34/149 (22%), Positives = 70/149 (46%), Gaps = 13/149 (8%) Query: 90 GSARGTTTTHLVQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146 GSARG Q + GD ++ G++ +SL + + VG+ + L Sbjct: 525 GSARGMALYEEEQVE------RVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDA 578 Query: 147 GGTVDPYARVSVSTQAGHR--HETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNF 204 G DP+ ++ + G + H+T++ + TL P F+E + I ++L +L + ++++ Sbjct: 579 NGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDY 638 Query: 205 KRFSGHEPLGELRLPLGTVDLQHVLEHWY 233 ++ +G +L + + L+HWY Sbjct: 639 DIGKSNDYIGGCQLGISAKGER--LKHWY 665 >gi|193804862 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 92.0 bits (227), Expect = 8e-19 Identities = 72/262 (27%), Positives = 121/262 (46%), Gaps = 32/262 (12%) Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLRPGGTV----DPYARVSVSTQAGH--RHETKVHR 172 GR+ SL+++ +Q + V +++ L +PY + + + +T + R Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 Query: 173 GTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHW 232 T+ P++DET + IP++ L TLQ +++ RF + LGE + + + L L+H Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 Query: 233 YLLGPPAATQ-----PEQVGELCFSLRYVPSS----------------GRLTVVVLEARG 271 L + + P GEL SL+Y+P+S G L V + EA+ Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 Query: 272 LRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL-VPFSQVQNVDL 326 L G ++ +VK L+ + K KRKT K T P++N F + V +Q++ L Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 Query: 327 VLAVWDRSLPLRTEPVGKVHLG 348 L VWDR + +G V LG Sbjct: 598 ELTVWDREPLASNDFLGGVRLG 619 >gi|193804860 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 92.0 bits (227), Expect = 8e-19 Identities = 72/262 (27%), Positives = 121/262 (46%), Gaps = 32/262 (12%) Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLRPGGTV----DPYARVSVSTQAGH--RHETKVHR 172 GR+ SL+++ +Q + V +++ L +PY + + + +T + R Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 Query: 173 GTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHW 232 T+ P++DET + IP++ L TLQ +++ RF + LGE + + + L L+H Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 Query: 233 YLLGPPAATQ-----PEQVGELCFSLRYVPSS----------------GRLTVVVLEARG 271 L + + P GEL SL+Y+P+S G L V + EA+ Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 Query: 272 LRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL-VPFSQVQNVDL 326 L G ++ +VK L+ + K KRKT K T P++N F + V +Q++ L Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 Query: 327 VLAVWDRSLPLRTEPVGKVHLG 348 L VWDR + +G V LG Sbjct: 598 ELTVWDREPLASNDFLGGVRLG 619 >gi|31881667 synaptotagmin XV isoform b [Homo sapiens] Length = 390 Score = 92.0 bits (227), Expect = 8e-19 Identities = 67/221 (30%), Positives = 107/221 (48%), Gaps = 11/221 (4%) Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLR-PGGTVDPYARVSVSTQAGHRHETKVHRGTLCP 177 GRL S+E++ ++ + VGL +A L+ P T P ++ + ++K R T P Sbjct: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNP 208 Query: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV----DLQHVLEHWY 233 FDE F + + L+ +++ R H+ LG++ PL D + V+ W Sbjct: 209 QFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVI--WR 266 Query: 234 LLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQ 289 L + P + G+L F L Y RLTVVVL A+GLR G+ +VKV LM + Sbjct: 267 DLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHN 326 Query: 290 RKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAV 330 + K +KT+ G+ P +NE F+F +++ L L V Sbjct: 327 KFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTV 367 Score = 40.0 bits (92), Expect = 0.004 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 4/102 (3%) Query: 246 VGELCFSLRYVPSSGRLTVVVLEARGLRPG--LAEPYVKVQLMLNQRKWKKRKTATKKGT 303 +G L FS+ Y + RL V +++A+ L+ P VK+ L+ ++R++ + KT K+ T Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKT--KRKT 205 Query: 304 AAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKV 345 + P F+E F F V + L +V+ + + +G+V Sbjct: 206 SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV 247 >gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] Length = 451 Score = 82.4 bits (202), Expect = 7e-16 Identities = 48/137 (35%), Positives = 71/137 (51%), Gaps = 4/137 (2%) Query: 244 EQVGELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTAT 299 E+ G + SL Y G L V VL L P G ++P+V++ L N K K KT+ Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365 Query: 300 KKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHW 359 + T P FNE F + P ++ L+++VWD L + +G V LG+ ASG+ L+HW Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHW 425 Query: 360 ADMLAHARRPIAQRHPL 376 + L H+ + HPL Sbjct: 426 LECLGHSDHRLELWHPL 442 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/122 (29%), Positives = 61/122 (50%), Gaps = 7/122 (5%) Query: 116 QQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--TKV 170 ++ G + LSL + + VG+ + A L P G DP+ R+ + AG + + T V Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365 Query: 171 HRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLE 230 HR TL P F+E + P+ EL TL V ++++ + + +G ++ LG+ L Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQ--LGSHASGERLR 423 Query: 231 HW 232 HW Sbjct: 424 HW 425 Score = 42.7 bits (99), Expect = 6e-04 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 16/135 (11%) Query: 101 VQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--GGTVDPYARVSV 158 +QPD + E D+ G L+ +L F+ + + +A L+P G+ D Y + ++ Sbjct: 69 LQPDPEP-EGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANL 127 Query: 159 STQAGHRHETKVH--RGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEP--- 212 A + + H RGT PV++ET +H + + TL+ L + P Sbjct: 128 LPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQ 187 Query: 213 -------LGELRLPL 220 LGELR+PL Sbjct: 188 RQWQAPSLGELRVPL 202 Score = 39.7 bits (91), Expect = 0.005 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%) Query: 246 VGELCFSLRYVPSSGRLTVVVLEARGLRP---GLAEPYVKVQLMLNQRKWKKRKTATKKG 302 +G L F+L + + L A+GL+P G A+ YVK L+ K + +T T +G Sbjct: 85 LGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANLLPGASKASQLRTHTVRG 144 Query: 303 TAAPYFNEAFTF 314 T P + E T+ Sbjct: 145 TRVPVWEETLTY 156 >gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens] Length = 451 Score = 82.4 bits (202), Expect = 7e-16 Identities = 48/137 (35%), Positives = 71/137 (51%), Gaps = 4/137 (2%) Query: 244 EQVGELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTAT 299 E+ G + SL Y G L V VL L P G ++P+V++ L N K K KT+ Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365 Query: 300 KKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHW 359 + T P FNE F + P ++ L+++VWD L + +G V LG+ ASG+ L+HW Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHW 425 Query: 360 ADMLAHARRPIAQRHPL 376 + L H+ + HPL Sbjct: 426 LECLGHSDHRLELWHPL 442 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/122 (29%), Positives = 61/122 (50%), Gaps = 7/122 (5%) Query: 116 QQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--TKV 170 ++ G + LSL + + VG+ + A L P G DP+ R+ + AG + + T V Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365 Query: 171 HRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLE 230 HR TL P F+E + P+ EL TL V ++++ + + +G ++ LG+ L Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQ--LGSHASGERLR 423 Query: 231 HW 232 HW Sbjct: 424 HW 425 Score = 42.7 bits (99), Expect = 6e-04 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 16/135 (11%) Query: 101 VQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--GGTVDPYARVSV 158 +QPD + E D+ G L+ +L F+ + + +A L+P G+ D Y + ++ Sbjct: 69 LQPDPEP-EGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANL 127 Query: 159 STQAGHRHETKVH--RGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEP--- 212 A + + H RGT PV++ET +H + + TL+ L + P Sbjct: 128 LPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQ 187 Query: 213 -------LGELRLPL 220 LGELR+PL Sbjct: 188 RQWQAPSLGELRVPL 202 Score = 39.7 bits (91), Expect = 0.005 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%) Query: 246 VGELCFSLRYVPSSGRLTVVVLEARGLRP---GLAEPYVKVQLMLNQRKWKKRKTATKKG 302 +G L F+L + + L A+GL+P G A+ YVK L+ K + +T T +G Sbjct: 85 LGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANLLPGASKASQLRTHTVRG 144 Query: 303 TAAPYFNEAFTF 314 T P + E T+ Sbjct: 145 TRVPVWEETLTY 156 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,547,084 Number of Sequences: 37866 Number of extensions: 877060 Number of successful extensions: 3861 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 92 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 3496 Number of HSP's gapped (non-prelim): 227 length of query: 401 length of database: 18,247,518 effective HSP length: 104 effective length of query: 297 effective length of database: 14,309,454 effective search space: 4249907838 effective search space used: 4249907838 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.