Guide to the Human Genome
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Search of human proteins with 94536846

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94536846 synaptotagmin VIII [Homo sapiens]
         (401 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94536846 synaptotagmin VIII [Homo sapiens]                         830   0.0  
gi|211059429 synaptotagmin II [Homo sapiens]                          295   6e-80
gi|31543670 synaptotagmin II [Homo sapiens]                           295   6e-80
gi|209447073 synaptotagmin I [Homo sapiens]                           283   1e-76
gi|5032139 synaptotagmin I [Homo sapiens]                             283   1e-76
gi|209447070 synaptotagmin I [Homo sapiens]                           283   1e-76
gi|92859638 synaptotagmin V [Homo sapiens]                            280   2e-75
gi|39752671 synaptotagmin X [Homo sapiens]                            171   1e-42
gi|45504376 synaptotagmin VI [Homo sapiens]                           167   2e-41
gi|28376627 synaptotagmin IX [Homo sapiens]                           166   5e-41
gi|38570146 synaptotagmin VII [Homo sapiens]                          161   1e-39
gi|238550198 synaptotagmin III [Homo sapiens]                         156   3e-38
gi|238550196 synaptotagmin III [Homo sapiens]                         156   3e-38
gi|14150054 synaptotagmin III [Homo sapiens]                          156   3e-38
gi|40068038 B/K protein [Homo sapiens]                                143   2e-34
gi|24308219 synaptotagmin IV [Homo sapiens]                           138   1e-32
gi|216548478 synaptotagmin XI [Homo sapiens]                          127   2e-29
gi|29366828 synaptotagmin XII [Homo sapiens]                          119   5e-27
gi|6005997 double C2-like domains, beta [Homo sapiens]                115   5e-26
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap...   108   7e-24
gi|24308233 synaptotagmin XIII [Homo sapiens]                         107   2e-23
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 107   2e-23
gi|47078261 double C2-like domains, alpha [Homo sapiens]               96   4e-20
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]             96   6e-20
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]              96   6e-20
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                       92   8e-19
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                       92   8e-19
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                  92   8e-19
gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]             82   7e-16
gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens]             82   7e-16

>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  830 bits (2143), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 1   MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGV 60
           MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGV
Sbjct: 1   MLHLHGWQTMQGRKMGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGV 60

Query: 61  LLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGR 120
           LLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGR
Sbjct: 61  LLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGR 120

Query: 121 LQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFD 180
           LQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFD
Sbjct: 121 LQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFD 180

Query: 181 ETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAA 240
           ETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAA
Sbjct: 181 ETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAA 240

Query: 241 TQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATK 300
           TQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATK
Sbjct: 241 TQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATK 300

Query: 301 KGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWA 360
           KGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWA
Sbjct: 301 KGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWA 360

Query: 361 DMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS 401
           DMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS
Sbjct: 361 DMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS 401


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  295 bits (754), Expect = 6e-80
 Identities = 157/360 (43%), Positives = 229/360 (63%), Gaps = 21/360 (5%)

Query: 45  PWPRWALIAGALAAGVLLVSCL--LCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQ 102
           P P WALIA A+ AG+LL++C   +C  CCC ++  KK + K   G+ +A         Q
Sbjct: 59  PLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGK---GMKNAMNMKDMKGGQ 115

Query: 103 PDVD---GLESSPGDAQQ------WGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTV 150
            D D   GL    G+ ++       G+LQ SL++DF + ++ VG+ QAA+L     GGT 
Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175

Query: 151 DPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGH 210
           DPY +V +      ++ETKVHR TL P F+ET  F +P  EL G TL + +++F RFS H
Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235

Query: 211 EPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEAR 270
           + +GE+++P+ TVDL   +E W  L      +PE++G++C SLRYVP++G+LTV +LEA+
Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295

Query: 271 GLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDL 326
            L+     GL++PYVK+ LM N ++ KK+KT  KK T  PYFNE+F+F +PF Q+Q V +
Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355

Query: 327 VLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRML 386
           V+ V D     + E +GK+ +G+ A+G  L+HW+DMLA+ RRPIAQ H L+P  EVD +L
Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  295 bits (754), Expect = 6e-80
 Identities = 157/360 (43%), Positives = 229/360 (63%), Gaps = 21/360 (5%)

Query: 45  PWPRWALIAGALAAGVLLVSCL--LCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQ 102
           P P WALIA A+ AG+LL++C   +C  CCC ++  KK + K   G+ +A         Q
Sbjct: 59  PLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGK---GMKNAMNMKDMKGGQ 115

Query: 103 PDVD---GLESSPGDAQQ------WGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTV 150
            D D   GL    G+ ++       G+LQ SL++DF + ++ VG+ QAA+L     GGT 
Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175

Query: 151 DPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGH 210
           DPY +V +      ++ETKVHR TL P F+ET  F +P  EL G TL + +++F RFS H
Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235

Query: 211 EPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEAR 270
           + +GE+++P+ TVDL   +E W  L      +PE++G++C SLRYVP++G+LTV +LEA+
Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295

Query: 271 GLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDL 326
            L+     GL++PYVK+ LM N ++ KK+KT  KK T  PYFNE+F+F +PF Q+Q V +
Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355

Query: 327 VLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRML 386
           V+ V D     + E +GK+ +G+ A+G  L+HW+DMLA+ RRPIAQ H L+P  EVD +L
Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  283 bits (725), Expect = 1e-76
 Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%)

Query: 45  PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97
           P P WALIA A+ A +L+++C  C    C  + + K + KE  G  +         G T 
Sbjct: 55  PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114

Query: 98  THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146
                 D D   GL     +  P + ++ G+LQ SL++DF + ++ VG+ QAA+L     
Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174

Query: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206
           GGT DPY +V +      + ETKVHR TL PVF+E   F +P +EL G TL + +++F R
Sbjct: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234

Query: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266
           FS H+ +GE ++P+ TVD  HV E W  L      + E++G++CFSLRYVP++G+LTVV+
Sbjct: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294

Query: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322
           LEA+ L+     GL++PYVK+ LM N ++ KK+KT  KK T  PY+NE+F+F VPF Q+Q
Sbjct: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354

Query: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382
            V +V+ V D     + + +GKV +G  ++G  L+HW+DMLA+ RRPIAQ H L+   EV
Sbjct: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414

Query: 383 DRMLALQ 389
           D MLA++
Sbjct: 415 DAMLAVK 421


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  283 bits (725), Expect = 1e-76
 Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%)

Query: 45  PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97
           P P WALIA A+ A +L+++C  C    C  + + K + KE  G  +         G T 
Sbjct: 55  PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114

Query: 98  THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146
                 D D   GL     +  P + ++ G+LQ SL++DF + ++ VG+ QAA+L     
Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174

Query: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206
           GGT DPY +V +      + ETKVHR TL PVF+E   F +P +EL G TL + +++F R
Sbjct: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234

Query: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266
           FS H+ +GE ++P+ TVD  HV E W  L      + E++G++CFSLRYVP++G+LTVV+
Sbjct: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294

Query: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322
           LEA+ L+     GL++PYVK+ LM N ++ KK+KT  KK T  PY+NE+F+F VPF Q+Q
Sbjct: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354

Query: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382
            V +V+ V D     + + +GKV +G  ++G  L+HW+DMLA+ RRPIAQ H L+   EV
Sbjct: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414

Query: 383 DRMLALQ 389
           D MLA++
Sbjct: 415 DAMLAVK 421


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  283 bits (725), Expect = 1e-76
 Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%)

Query: 45  PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97
           P P WALIA A+ A +L+++C  C    C  + + K + KE  G  +         G T 
Sbjct: 55  PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114

Query: 98  THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146
                 D D   GL     +  P + ++ G+LQ SL++DF + ++ VG+ QAA+L     
Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174

Query: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206
           GGT DPY +V +      + ETKVHR TL PVF+E   F +P +EL G TL + +++F R
Sbjct: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234

Query: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266
           FS H+ +GE ++P+ TVD  HV E W  L      + E++G++CFSLRYVP++G+LTVV+
Sbjct: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294

Query: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322
           LEA+ L+     GL++PYVK+ LM N ++ KK+KT  KK T  PY+NE+F+F VPF Q+Q
Sbjct: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354

Query: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382
            V +V+ V D     + + +GKV +G  ++G  L+HW+DMLA+ RRPIAQ H L+   EV
Sbjct: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414

Query: 383 DRMLALQ 389
           D MLA++
Sbjct: 415 DAMLAVK 421


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  280 bits (715), Expect = 2e-75
 Identities = 163/380 (42%), Positives = 227/380 (59%), Gaps = 21/380 (5%)

Query: 22  PSAPAPAGTTAIPGLIPDL--VAGTPWPRWALIAGALAAGVLLVSCLLCAACCCCRRHR- 78
           P  P P   +  P   PD   ++  P P WAL    L +G+L+ SC  C     CRR   
Sbjct: 3   PEPPTPGPPS--PDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG 60

Query: 79  KKPRDKESVGLGSARGTTTTHL--VQPDVDGLESSPG-------DAQQWGRLQLSLEFDF 129
           KK + +  V L   +G   +++  VQP+V+ LE +P        D  + GRLQ SL++DF
Sbjct: 61  KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF 120

Query: 130 GSQEIRVGLRQA---ADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH 186
            S ++ VG+ QA   A L  GG+ DPY RV +      R+ETKVHR TL P F ET  F 
Sbjct: 121 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK 180

Query: 187 IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQV 246
           +P  EL G  L + +++F RFS ++ +GE+R+P+ +VDL   ++ W  L      + E++
Sbjct: 181 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL 240

Query: 247 GELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKG 302
           G++CFSLRYVP++G+LTV+VLEA+ L+     GL++PYVKV L+   +K +K+KT  KK 
Sbjct: 241 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN 300

Query: 303 TAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADM 362
           T  PY+NEAF+F VP  QVQ V + L V D     + E +G+V +GA A G  L+HWADM
Sbjct: 301 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM 360

Query: 363 LAHARRPIAQRHPLRPAREV 382
           LA+ RRPIAQ H LRP   V
Sbjct: 361 LANPRRPIAQWHSLRPPDRV 380


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  171 bits (432), Expect = 1e-42
 Identities = 113/325 (34%), Positives = 164/325 (50%), Gaps = 24/325 (7%)

Query: 75  RRHRKKPRDKESVGLGSA------RGTTTTHL--------VQPDVDGLESSPGDAQQWGR 120
           RRH  +     SV           RG TTT +         Q  VD   +   D +  G+
Sbjct: 175 RRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGK 234

Query: 121 LQLSLEFDFGSQEIRVGLRQAADLRPG---GTVDPYARVSVSTQAGHRHETKVHRGTLCP 177
           L  +L++D+ ++ + V + +A DL      GT DPY ++ +      + +T+VHR TL P
Sbjct: 235 LNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNP 294

Query: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLP--LGTVDLQHVLEHWYLL 235
           +FDET  F +   +L    L   +++F RFS H+ +GE+ L       DL      W  +
Sbjct: 295 LFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDI 354

Query: 236 GPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRK 291
              A T+   +GE+ FSL Y+P++GR+T+ V++ R L+     G ++PYVKV LM   R+
Sbjct: 355 HC-ATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413

Query: 292 WKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARA 351
            KKRKT TKK T  P +NEA  F +P   V  V L +AV D       E +G    G  A
Sbjct: 414 LKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDA 473

Query: 352 SGQPLQHWADMLAHARRPIAQRHPL 376
            G    HW +MLA+ R+PI   HPL
Sbjct: 474 EGLGRDHWNEMLAYHRKPITHWHPL 498


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  167 bits (423), Expect = 2e-41
 Identities = 99/284 (34%), Positives = 154/284 (54%), Gaps = 10/284 (3%)

Query: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRPG---GTVDPYARVSV 158
           Q  VDG ++     +  G++  SL +D+ ++ + V + +A DL      G+ DPY ++ +
Sbjct: 129 QKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYL 188

Query: 159 STQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218
                 + +T+VHR TL P FDE   F +P  EL    L + +F+F RFS H+ +GE+ L
Sbjct: 189 LPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVIL 248

Query: 219 P--LGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274
                  DL      W  +   A ++   +GE+ FSL Y+P++GRLT+ V++ R L+   
Sbjct: 249 DNLFEASDLSRETSIWKDI-QYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMD 307

Query: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWD 332
             G ++PYVKV L+ + R+ KK+KT  KK T  P +NEA  F +P   +  V L+++V D
Sbjct: 308 ITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMD 367

Query: 333 RSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376
                  E +G   +G  A G    HW +MLA+ R+PIA  H L
Sbjct: 368 YDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  166 bits (419), Expect = 5e-41
 Identities = 97/284 (34%), Positives = 153/284 (53%), Gaps = 10/284 (3%)

Query: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSV 158
           Q  +D  +    +++  G+L   L++D   +++ V + +A +L      GT DPY ++ +
Sbjct: 205 QRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYL 264

Query: 159 STQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218
                 +H+TKVHR TL PVFDE   F +P  +L    L   +++F RFS H+ +G++ +
Sbjct: 265 LPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVV 324

Query: 219 P--LGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274
              L   D       W  +          +GEL FSL Y+P++GRLT+ +++AR L+   
Sbjct: 325 DHFLDLADFPRECILWKDI-EYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMD 383

Query: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWD 332
             G ++PYVKV LM + R+ KKRKT+TK+ T  P +NEA  F VP   +  + L +AV D
Sbjct: 384 ITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMD 443

Query: 333 RSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376
                  E +G   +G  A      HW++ML++ R+PIA  H L
Sbjct: 444 YDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSL 487


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  161 bits (407), Expect = 1e-39
 Identities = 98/309 (31%), Positives = 170/309 (55%), Gaps = 12/309 (3%)

Query: 78  RKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQ-WGRLQLSLEFDFGSQEIRV 136
           R +PR   S  + S   T+   ++ P  +  E+  G +++  GR+Q S+ ++F    + V
Sbjct: 97  RTEPRSSVSDLVNSL--TSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTV 154

Query: 137 GLRQAADLRP---GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAEL 192
            + +A +L      GT DP+ ++ +     H+ ETKV R  L P ++ET  F   P  ++
Sbjct: 155 KIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKV 214

Query: 193 PGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFS 252
               L +Q+ ++ RFS ++P+GE+ +PL  VDL  +   W  L P +     + GEL  S
Sbjct: 215 VQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSR-GELLLS 273

Query: 253 LRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYF 308
           L Y PS+  + V +++AR L+     G ++PYVKV LM   ++ +K+KT T K    P F
Sbjct: 274 LCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIF 333

Query: 309 NEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARR 368
           NE+F F +P  +++   +++ V D+    R + +GK++L  ++    ++HW DM+A  R+
Sbjct: 334 NESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQ 393

Query: 369 PIAQRHPLR 377
           P+AQ H L+
Sbjct: 394 PVAQWHQLK 402


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  156 bits (395), Expect = 3e-38
 Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%)

Query: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169
           G     GR+  +L + +GS ++ V + QA DL      G  DPY ++ +      + +TK
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354

Query: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229
           VHR TL PVF+ET  F +P AEL    L   +++F RFS H+ +G+       V L ++L
Sbjct: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407

Query: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275
           E      PP            ++   +GEL FSL Y+P++GRLTV +++A  L+     G
Sbjct: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465

Query: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335
            ++PYVK  L+   R+ KKRKT+ KK T  P +NEA  F V    V+NV L +AV D   
Sbjct: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525

Query: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376
               E +G   +G  A+     +HWA+MLA+ R+P+   H L
Sbjct: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  156 bits (395), Expect = 3e-38
 Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%)

Query: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169
           G     GR+  +L + +GS ++ V + QA DL      G  DPY ++ +      + +TK
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354

Query: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229
           VHR TL PVF+ET  F +P AEL    L   +++F RFS H+ +G+       V L ++L
Sbjct: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407

Query: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275
           E      PP            ++   +GEL FSL Y+P++GRLTV +++A  L+     G
Sbjct: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465

Query: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335
            ++PYVK  L+   R+ KKRKT+ KK T  P +NEA  F V    V+NV L +AV D   
Sbjct: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525

Query: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376
               E +G   +G  A+     +HWA+MLA+ R+P+   H L
Sbjct: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  156 bits (395), Expect = 3e-38
 Identities = 102/282 (36%), Positives = 150/282 (53%), Gaps = 27/282 (9%)

Query: 113 GDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETK 169
           G     GR+  +L + +GS ++ V + QA DL      G  DPY ++ +      + +TK
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTK 354

Query: 170 VHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVL 229
           VHR TL PVF+ET  F +P AEL    L   +++F RFS H+ +G+       V L ++L
Sbjct: 355 VHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQ-------VVLDNLL 407

Query: 230 EHWYLLGPP----------AATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PG 275
           E      PP            ++   +GEL FSL Y+P++GRLTV +++A  L+     G
Sbjct: 408 E--LAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTG 465

Query: 276 LAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSL 335
            ++PYVK  L+   R+ KKRKT+ KK T  P +NEA  F V    V+NV L +AV D   
Sbjct: 466 FSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDC 525

Query: 336 PLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376
               E +G   +G  A+     +HWA+MLA+ R+P+   H L
Sbjct: 526 IGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  143 bits (361), Expect = 2e-34
 Identities = 96/298 (32%), Positives = 153/298 (51%), Gaps = 17/298 (5%)

Query: 104 DVDGL-ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRPGGTVD----------P 152
           DVD L +       Q G L  S ++D     + V + +A DL P  + D          P
Sbjct: 170 DVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNP 229

Query: 153 YARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEP 212
           Y ++ +     +  +T V R T  PVF+E   F IP  E    TL + + +F +FS H  
Sbjct: 230 YVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCV 289

Query: 213 LGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGL 272
           +G++ +PL  VDL     HW+    P++    ++GEL  SL Y+PS+GRL V V+ A+ L
Sbjct: 290 IGKVSVPLCEVDLVKG-GHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQL 348

Query: 273 RPGL----AEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVL 328
                   ++P+VK+QL+   +  K +KT+  +GT  P++NE+F+F VP  +++N  LV 
Sbjct: 349 LQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVF 408

Query: 329 AVWDRSLPLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPLRPAREVDRM 385
            V+  ++    + +G++ +G  +SG     HW  ML   R  + Q H LR   E DR+
Sbjct: 409 TVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRV 466


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  138 bits (347), Expect = 1e-32
 Identities = 98/305 (32%), Positives = 158/305 (51%), Gaps = 23/305 (7%)

Query: 83  DKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAA 142
           +KESV   S + +T+            +S    ++ G L  SLE++F  +   V +++A 
Sbjct: 130 EKESVSPESLKSSTSL-----------TSEEKQEKLGTLFFSLEYNFERKAFVVNIKEAR 178

Query: 143 DL----RPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAELPGATL 197
            L        T DPY ++++  +  H+ +T+V R TL P FDET  F+ IP  ++    L
Sbjct: 179 GLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELAL 238

Query: 198 QVQLFNFKRFSGHEPLGELRLPLGTVDLQH--VLEHWYLLGPPAATQPEQVGELCFSLRY 255
              + +F RFS  + +GE+ +PL  ++L    +L +  ++         + GEL  SL Y
Sbjct: 239 HFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGR-GELLISLCY 297

Query: 256 VPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEA 311
             ++  LTVVVL+AR L      GL++PYVKV L   +++  K+KT  KK T    FNE 
Sbjct: 298 QSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNEL 357

Query: 312 FTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIA 371
           F F +P   ++++ +   V D     R E +G++ LGA A G   +HW ++  + RR IA
Sbjct: 358 FVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIA 417

Query: 372 QRHPL 376
           + H L
Sbjct: 418 KWHVL 422


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  127 bits (319), Expect = 2e-29
 Identities = 94/288 (32%), Positives = 149/288 (51%), Gaps = 30/288 (10%)

Query: 110 SSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADL-----RPGGTVDPYARVSVSTQAGH 164
           SSP +    G L  S++++F  + + V +++A  L     +  G+ DPY ++++     H
Sbjct: 150 SSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGS-DPYIKMTILPDKRH 208

Query: 165 RHETKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV 223
           R +T+V R TL PVFDET  F+ IP ++L    L   + +F RFS  + +GE+ +PL  V
Sbjct: 209 RVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV 268

Query: 224 DLQHVLEHWYLLGPPAATQPE---------QVGELCFSLRYVPSSGRLTVVVLEARGLRP 274
           D           G    T+             GEL  SL Y P + R+TVVVL+AR L  
Sbjct: 269 DPS--------TGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPK 320

Query: 275 ----GLA-EPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLA 329
               GL+  PYVKV +   +++  K+KT  KK T  P FNE+F + +P   + ++ +   
Sbjct: 321 MDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFL 380

Query: 330 VWDRSLPLRTEPVGKVHLGARA-SGQPLQHWADMLAHARRPIAQRHPL 376
           V D     + E VG++ LGA + +    +HW ++    R+P+A+ H L
Sbjct: 381 VIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  119 bits (298), Expect = 5e-27
 Identities = 83/266 (31%), Positives = 128/266 (48%), Gaps = 7/266 (2%)

Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADL---RPGGTVDPYARVSVSTQAGHRHETKVHRGTL 175
           G++++S+E+D  S  + V + Q  DL           + RVS+         +++ R   
Sbjct: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213

Query: 176 CPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLL 235
              FDE     +    L   +L+  +F       +   G + L L  +DL       +L 
Sbjct: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLY 273

Query: 236 GPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGL----RPGLAEPYVKVQLMLNQRK 291
                   + VGE+  SL Y+P++ RLTVVV++A+ L        A+P+VKV L+ + RK
Sbjct: 274 LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRK 333

Query: 292 WKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARA 351
             K+KTA K+    P FNEA  F VP   +Q++ L + V + S   R + VG V +G  A
Sbjct: 334 MSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSA 393

Query: 352 SGQPLQHWADMLAHARRPIAQRHPLR 377
           SG    HW  MLA  RRP++  H +R
Sbjct: 394 SGMGTTHWNQMLATLRRPVSMWHAVR 419


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  115 bits (289), Expect = 5e-26
 Identities = 86/291 (29%), Positives = 134/291 (46%), Gaps = 18/291 (6%)

Query: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSV 158
           +PD DG ES   D    G L  SL +D  +  +   + +A  L+P    G  DPY ++ +
Sbjct: 113 EPDADGYESD--DCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHL 170

Query: 159 STQAGHRHE--TKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGE 215
              A   ++  TK  R TL P ++ET  ++ I   ++   TL++ + +  +F  +E +GE
Sbjct: 171 LPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGE 230

Query: 216 LRLPLGTVDLQHV------LEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEA 269
            R+PL  +   H       LE    +        E+ G +  SL+Y      L V ++  
Sbjct: 231 TRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRC 290

Query: 270 RGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVD 325
             L      G ++PYVK  L  +  K  K KTA KK T  P FNE F + +    +    
Sbjct: 291 AHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKS 350

Query: 326 LVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376
           L + VWD  +    + +G V LG  A G+ L+HW D L +  + I + H L
Sbjct: 351 LEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTL 401


>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
           sapiens]
          Length = 431

 Score =  108 bits (271), Expect = 7e-24
 Identities = 87/301 (28%), Positives = 135/301 (44%), Gaps = 26/301 (8%)

Query: 101 VQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--GGTVDPYARVSV 158
           +QPD +  E    D+   G L+ +L F+  +  +     +A  L+P   G+ D Y + ++
Sbjct: 123 LQPDPEP-EGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANL 181

Query: 159 STQAGHRHETKVH--RGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEP--- 212
              A    + + H  RGT  PV++ET  +H   + +    TL+  L   +      P   
Sbjct: 182 LPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQ 241

Query: 213 -------LGELRLPLGTV------DLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSS 259
                  LGELR+PL  +           LE   L         E+ G +  SL Y    
Sbjct: 242 RQWQAPSLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQ 301

Query: 260 GRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL 315
           G L V VL    L P    G ++P+V++ L  N  K  K KT+  + T  P FNE F + 
Sbjct: 302 GGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYS 361

Query: 316 VPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHP 375
            P  ++    L+++VWD  L    + +G V LG+ ASG+ L+HW + L H+   +   HP
Sbjct: 362 GPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHP 421

Query: 376 L 376
           L
Sbjct: 422 L 422


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  107 bits (267), Expect = 2e-23
 Identities = 86/287 (29%), Positives = 129/287 (44%), Gaps = 11/287 (3%)

Query: 101 VQPDVDGLES-SPGDAQQWG---RLQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARV 156
           V  DV  +E+ +P  A  W    +L   L++D    E+ V   +A      G  D Y + 
Sbjct: 138 VVEDVCVMETWNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAVTSNHDGGCDCYVQG 197

Query: 157 SVSTQAGH-RHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGE 215
           SV+ + G    +T + +  L   ++E     + + ELP ATL + L    RFS H   GE
Sbjct: 198 SVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGE 257

Query: 216 LRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPG 275
           LRL L    +      W  L   A       GE+  S+ Y+P++ RL VV+++A+ L   
Sbjct: 258 LRLGLDGTSVPLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSN 317

Query: 276 LAEPY------VKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLA 329
            ++        VKV L    RK KK++T   K    P +NE   F +P   +Q   + L 
Sbjct: 318 QSKELLGKDVSVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELE 377

Query: 330 VWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376
           V  +    ++  +G   LG   SG    HW +ML + RR IA  H L
Sbjct: 378 VLGQDDSGQSCALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQL 424


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  107 bits (267), Expect = 2e-23
 Identities = 78/269 (28%), Positives = 131/269 (48%), Gaps = 13/269 (4%)

Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLR-PGGTVDPYARVSVSTQAGHRHETKVHRGTLCP 177
           GRL  S+E++  ++ + VGL +A  L+ P  T  P  ++ +        ++K  R T  P
Sbjct: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNP 208

Query: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV----DLQHVLEHWY 233
            FDE   F +    +    L+  +++  R   H+ LG++  PL       D + V+  W 
Sbjct: 209 QFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVI--WR 266

Query: 234 LLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQ 289
            L   +   P + G+L F L Y     RLTVVVL A+GLR     G+   +VKV LM + 
Sbjct: 267 DLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHN 326

Query: 290 RKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLG- 348
           +  K +KT+   G+  P +NE F+F    +++    L L V       +++ +G+V +G 
Sbjct: 327 KFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP 386

Query: 349 -ARASGQPLQHWADMLAHARRPIAQRHPL 376
                G+ L+HW +ML+  +  + + H L
Sbjct: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 83/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (12%)

Query: 104 DVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVST 160
           +VD  +S   DA   G L+  L +D  S  +   + +A  L+P    G  DPY ++ +  
Sbjct: 78  EVDSYDSD--DATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLP 135

Query: 161 QA--GHRHETKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELR 217
            A   ++ +TK  R TL PV++E   +  I   ++    L++ + +  + S +E +GE+R
Sbjct: 136 GACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIR 195

Query: 218 LPLGTV------DLQHVLEHWYLLGPPAATQP----------------------EQVGEL 249
           +PL  +           LE    L  P++                         E+ G +
Sbjct: 196 VPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRI 255

Query: 250 CFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAA 305
             SL Y      L V +L    L      G ++PYVK  L  +  K  K KT  KK T  
Sbjct: 256 LLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLN 315

Query: 306 PYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAH 365
           P FNE F + +  S +    L + VWD  +    + +G V LG  A G+  +HW+D L  
Sbjct: 316 PEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQ 375

Query: 366 ARRPIAQRHPL 376
               + + H L
Sbjct: 376 PDAALERWHTL 386



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 45/139 (32%), Positives = 65/139 (46%), Gaps = 23/139 (16%)

Query: 235 LGPPAA----TQPEQ--------------VGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274
           L PPAA    T PE               +G L F L Y  +S  L   +L A+GL+P  
Sbjct: 61  LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD 120

Query: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL-VPFSQVQNVDLVLAVW 331
             GLA+PYVK+ L+    K  K KT T++ T  P +NE  T+  +    + +  L +AV 
Sbjct: 121 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC 180

Query: 332 DRSLPLRTEPVGKVHLGAR 350
           D       E +G++ +  R
Sbjct: 181 DEDKLSHNEFIGEIRVPLR 199



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 41/157 (26%), Positives = 70/157 (44%), Gaps = 20/157 (12%)

Query: 104 DVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVST 160
           +++  E   G  ++ GR+ LSL +    + + VG+ + A L      G  DPY +  +  
Sbjct: 238 ELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRP 297

Query: 161 QAGHR--HETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218
               +  H+T V + TL P F+E   + I  + L   TL+V ++++     ++ +G + L
Sbjct: 298 DVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSL 357

Query: 219 PLGTVD---------LQH---VLEHWYLLG---PPAA 240
             G            LQ     LE W+ L    PPAA
Sbjct: 358 GPGARGEARKHWSDCLQQPDAALERWHTLTSELPPAA 394


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 80/303 (26%), Positives = 135/303 (44%), Gaps = 34/303 (11%)

Query: 114 DAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--T 168
           +A   G L+ SL +D  +  ++  + +A  L+P    G  DPY ++ +   A   ++  T
Sbjct: 389 EATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRT 448

Query: 169 KVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV---- 223
           K  R T  P+++ET  +H I   ++   TL++ + +  +F  +E +GE R  L  +    
Sbjct: 449 KTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQ 508

Query: 224 --DLQHVLEHWYLLGPPAAT---------QPEQV---------GELCFSLRYVPSSGRLT 263
             +    LE    +     T         + EQV         G++  SL Y    G L 
Sbjct: 509 RKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLI 568

Query: 264 VVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFS 319
           V ++    L      G ++P+VK+ L  +  K  K KT  KK T  P FNE F + +  S
Sbjct: 569 VGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHS 628

Query: 320 QVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPA 379
            +    L ++VWD  +    + +G   LG  A G+ L+HW + L +  + I + H L+  
Sbjct: 629 DLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNE 688

Query: 380 REV 382
             V
Sbjct: 689 NHV 691



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/149 (22%), Positives = 70/149 (46%), Gaps = 13/149 (8%)

Query: 90  GSARGTTTTHLVQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146
           GSARG       Q +        GD ++ G++ +SL +      + VG+ +   L     
Sbjct: 529 GSARGMALYEEEQVE------RVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDA 582

Query: 147 GGTVDPYARVSVSTQAGHR--HETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNF 204
            G  DP+ ++ +    G +  H+T++ + TL P F+E   + I  ++L   +L + ++++
Sbjct: 583 NGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDY 642

Query: 205 KRFSGHEPLGELRLPLGTVDLQHVLEHWY 233
                ++ +G  +L +     +  L+HWY
Sbjct: 643 DIGKSNDYIGGCQLGISAKGER--LKHWY 669


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 80/303 (26%), Positives = 135/303 (44%), Gaps = 34/303 (11%)

Query: 114 DAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--T 168
           +A   G L+ SL +D  +  ++  + +A  L+P    G  DPY ++ +   A   ++  T
Sbjct: 385 EATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRT 444

Query: 169 KVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV---- 223
           K  R T  P+++ET  +H I   ++   TL++ + +  +F  +E +GE R  L  +    
Sbjct: 445 KTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQ 504

Query: 224 --DLQHVLEHWYLLGPPAAT---------QPEQV---------GELCFSLRYVPSSGRLT 263
             +    LE    +     T         + EQV         G++  SL Y    G L 
Sbjct: 505 RKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLI 564

Query: 264 VVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFS 319
           V ++    L      G ++P+VK+ L  +  K  K KT  KK T  P FNE F + +  S
Sbjct: 565 VGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHS 624

Query: 320 QVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPA 379
            +    L ++VWD  +    + +G   LG  A G+ L+HW + L +  + I + H L+  
Sbjct: 625 DLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNE 684

Query: 380 REV 382
             V
Sbjct: 685 NHV 687



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/149 (22%), Positives = 70/149 (46%), Gaps = 13/149 (8%)

Query: 90  GSARGTTTTHLVQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146
           GSARG       Q +        GD ++ G++ +SL +      + VG+ +   L     
Sbjct: 525 GSARGMALYEEEQVE------RVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDA 578

Query: 147 GGTVDPYARVSVSTQAGHR--HETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNF 204
            G  DP+ ++ +    G +  H+T++ + TL P F+E   + I  ++L   +L + ++++
Sbjct: 579 NGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDY 638

Query: 205 KRFSGHEPLGELRLPLGTVDLQHVLEHWY 233
                ++ +G  +L +     +  L+HWY
Sbjct: 639 DIGKSNDYIGGCQLGISAKGER--LKHWY 665


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 72/262 (27%), Positives = 121/262 (46%), Gaps = 32/262 (12%)

Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLRPGGTV----DPYARVSVSTQAGH--RHETKVHR 172
           GR+  SL+++  +Q + V +++   L          +PY +  +        + +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 173 GTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHW 232
            T+ P++DET  + IP++ L   TLQ  +++  RF  +  LGE  + + +  L   L+H 
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 233 YLLGPPAATQ-----PEQVGELCFSLRYVPSS----------------GRLTVVVLEARG 271
             L    + +     P   GEL  SL+Y+P+S                G L V + EA+ 
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 272 LRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL-VPFSQVQNVDL 326
           L      G ++ +VK  L+  + K  KRKT   K T  P++N  F +  V    +Q++ L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 327 VLAVWDRSLPLRTEPVGKVHLG 348
            L VWDR      + +G V LG
Sbjct: 598 ELTVWDREPLASNDFLGGVRLG 619


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 72/262 (27%), Positives = 121/262 (46%), Gaps = 32/262 (12%)

Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLRPGGTV----DPYARVSVSTQAGH--RHETKVHR 172
           GR+  SL+++  +Q + V +++   L          +PY +  +        + +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 173 GTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHW 232
            T+ P++DET  + IP++ L   TLQ  +++  RF  +  LGE  + + +  L   L+H 
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 233 YLLGPPAATQ-----PEQVGELCFSLRYVPSS----------------GRLTVVVLEARG 271
             L    + +     P   GEL  SL+Y+P+S                G L V + EA+ 
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 272 LRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFL-VPFSQVQNVDL 326
           L      G ++ +VK  L+  + K  KRKT   K T  P++N  F +  V    +Q++ L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 327 VLAVWDRSLPLRTEPVGKVHLG 348
            L VWDR      + +G V LG
Sbjct: 598 ELTVWDREPLASNDFLGGVRLG 619


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 67/221 (30%), Positives = 107/221 (48%), Gaps = 11/221 (4%)

Query: 119 GRLQLSLEFDFGSQEIRVGLRQAADLR-PGGTVDPYARVSVSTQAGHRHETKVHRGTLCP 177
           GRL  S+E++  ++ + VGL +A  L+ P  T  P  ++ +        ++K  R T  P
Sbjct: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNP 208

Query: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV----DLQHVLEHWY 233
            FDE   F +    +    L+  +++  R   H+ LG++  PL       D + V+  W 
Sbjct: 209 QFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVI--WR 266

Query: 234 LLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQ 289
            L   +   P + G+L F L Y     RLTVVVL A+GLR     G+   +VKV LM + 
Sbjct: 267 DLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHN 326

Query: 290 RKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAV 330
           +  K +KT+   G+  P +NE F+F    +++    L L V
Sbjct: 327 KFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTV 367



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 4/102 (3%)

Query: 246 VGELCFSLRYVPSSGRLTVVVLEARGLRPG--LAEPYVKVQLMLNQRKWKKRKTATKKGT 303
           +G L FS+ Y   + RL V +++A+ L+       P VK+ L+ ++R++ + KT  K+ T
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKT--KRKT 205

Query: 304 AAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKV 345
           + P F+E F F V    +    L  +V+      + + +G+V
Sbjct: 206 SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV 247


>gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]
          Length = 451

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 48/137 (35%), Positives = 71/137 (51%), Gaps = 4/137 (2%)

Query: 244 EQVGELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTAT 299
           E+ G +  SL Y    G L V VL    L P    G ++P+V++ L  N  K  K KT+ 
Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365

Query: 300 KKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHW 359
            + T  P FNE F +  P  ++    L+++VWD  L    + +G V LG+ ASG+ L+HW
Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHW 425

Query: 360 ADMLAHARRPIAQRHPL 376
            + L H+   +   HPL
Sbjct: 426 LECLGHSDHRLELWHPL 442



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 36/122 (29%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 116 QQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--TKV 170
           ++ G + LSL +      + VG+ + A L P    G  DP+ R+ +   AG + +  T V
Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365

Query: 171 HRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLE 230
           HR TL P F+E   +  P+ EL   TL V ++++   +  + +G ++  LG+      L 
Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQ--LGSHASGERLR 423

Query: 231 HW 232
           HW
Sbjct: 424 HW 425



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 16/135 (11%)

Query: 101 VQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--GGTVDPYARVSV 158
           +QPD +  E    D+   G L+ +L F+  +  +     +A  L+P   G+ D Y + ++
Sbjct: 69  LQPDPEP-EGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANL 127

Query: 159 STQAGHRHETKVH--RGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEP--- 212
              A    + + H  RGT  PV++ET  +H   + +    TL+  L   +      P   
Sbjct: 128 LPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQ 187

Query: 213 -------LGELRLPL 220
                  LGELR+PL
Sbjct: 188 RQWQAPSLGELRVPL 202



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 246 VGELCFSLRYVPSSGRLTVVVLEARGLRP---GLAEPYVKVQLMLNQRKWKKRKTATKKG 302
           +G L F+L +   +  L      A+GL+P   G A+ YVK  L+    K  + +T T +G
Sbjct: 85  LGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANLLPGASKASQLRTHTVRG 144

Query: 303 TAAPYFNEAFTF 314
           T  P + E  T+
Sbjct: 145 TRVPVWEETLTY 156


>gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens]
          Length = 451

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 48/137 (35%), Positives = 71/137 (51%), Gaps = 4/137 (2%)

Query: 244 EQVGELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTAT 299
           E+ G +  SL Y    G L V VL    L P    G ++P+V++ L  N  K  K KT+ 
Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365

Query: 300 KKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHW 359
            + T  P FNE F +  P  ++    L+++VWD  L    + +G V LG+ ASG+ L+HW
Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHW 425

Query: 360 ADMLAHARRPIAQRHPL 376
            + L H+   +   HPL
Sbjct: 426 LECLGHSDHRLELWHPL 442



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 36/122 (29%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 116 QQWGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHE--TKV 170
           ++ G + LSL +      + VG+ + A L P    G  DP+ R+ +   AG + +  T V
Sbjct: 306 EECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSV 365

Query: 171 HRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLE 230
           HR TL P F+E   +  P+ EL   TL V ++++   +  + +G ++  LG+      L 
Sbjct: 366 HRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADDFIGGVQ--LGSHASGERLR 423

Query: 231 HW 232
           HW
Sbjct: 424 HW 425



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 16/135 (11%)

Query: 101 VQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--GGTVDPYARVSV 158
           +QPD +  E    D+   G L+ +L F+  +  +     +A  L+P   G+ D Y + ++
Sbjct: 69  LQPDPEP-EGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANL 127

Query: 159 STQAGHRHETKVH--RGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEP--- 212
              A    + + H  RGT  PV++ET  +H   + +    TL+  L   +      P   
Sbjct: 128 LPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQ 187

Query: 213 -------LGELRLPL 220
                  LGELR+PL
Sbjct: 188 RQWQAPSLGELRVPL 202



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 246 VGELCFSLRYVPSSGRLTVVVLEARGLRP---GLAEPYVKVQLMLNQRKWKKRKTATKKG 302
           +G L F+L +   +  L      A+GL+P   G A+ YVK  L+    K  + +T T +G
Sbjct: 85  LGTLEFTLLFEADNSALHCTAHRAKGLKPLASGSADAYVKANLLPGASKASQLRTHTVRG 144

Query: 303 TAAPYFNEAFTF 314
           T  P + E  T+
Sbjct: 145 TRVPVWEETLTY 156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,547,084
Number of Sequences: 37866
Number of extensions: 877060
Number of successful extensions: 3861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 3496
Number of HSP's gapped (non-prelim): 227
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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