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Search of human proteins with 94421462
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 734 0.0
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 734 0.0
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 734 0.0
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 734 0.0
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 734 0.0
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 732 0.0
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 724 0.0
gi|4503383 dopamine receptor D1 [Homo sapiens] 219 2e-57
gi|4503391 dopamine receptor D5 [Homo sapiens] 211 1e-54
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 209 4e-54
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 209 4e-54
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 207 1e-53
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 204 1e-52
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 201 8e-52
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 195 6e-50
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 195 6e-50
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 195 6e-50
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 192 3e-49
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 190 1e-48
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 187 1e-47
gi|28173558 trace amine associated receptor 6 [Homo sapiens] 178 6e-45
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 177 1e-44
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 177 2e-44
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 174 8e-44
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 174 8e-44
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 174 8e-44
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 174 8e-44
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 174 1e-43
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 171 1e-42
gi|16751917 trace amine associated receptor 8 [Homo sapiens] 170 2e-42
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 734 bits (1895), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 734 bits (1895), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 734 bits (1895), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 734 bits (1895), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 734 bits (1895), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 732 bits (1890), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 724 bits (1870), Expect = 0.0
Identities = 359/373 (96%), Positives = 359/373 (96%), Gaps = 14/373 (3%)
Query: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180
Query: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226
IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240
Query: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286
QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300
Query: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346
YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360
Query: 347 STTTINGSTHVLR 359
STTTINGSTHVLR
Sbjct: 361 STTTINGSTHVLR 373
>gi|4503383 dopamine receptor D1 [Homo sapiens]
Length = 446
Score = 219 bits (559), Expect = 2e-57
Identities = 127/349 (36%), Positives = 190/349 (54%), Gaps = 32/349 (9%)
Query: 7 NVSSEEGFGSVE------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
N S+ +G G V +++ FLS +IL +LGN LV AV R LR TN+F++
Sbjct: 5 NTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVI 64
Query: 61 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
SLA +DLLV+VLVMP+ A+ + W +G FC + + D++ +TASI +LC IS+DRY+
Sbjct: 65 SLAVSDLLVAVLVMPWKAVAEIAGFWPFGS-FCNIWVAFDIMCSTASILNLCVISVDRYW 123
Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
AI P Y KMTP +++ W + ISF+P+ W+ + +
Sbjct: 124 AI-SSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAET 182
Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSE--- 237
C +++ YAI+ SV++FYIP +M++ Y RIY A++ +I L+RA ++
Sbjct: 183 IDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQ 242
Query: 238 -----------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI- 285
S+P+S+ + S R ETK KTL +IMG F CW PFF+ N + PF
Sbjct: 243 TTTGNGKPVECSQPESSFKMSFKR---ETKVLKTLSVIMGVFVCCWLPFFILNCILPFCG 299
Query: 286 -----DYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC 329
+ + + F+W G+ NS LNP +YAF N FR+AF +L C
Sbjct: 300 SGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAF-NADFRKAFSTLLGC 347
>gi|4503391 dopamine receptor D5 [Homo sapiens]
Length = 477
Score = 211 bits (536), Expect = 1e-54
Identities = 127/347 (36%), Positives = 185/347 (53%), Gaps = 31/347 (8%)
Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
+VV L+ +I+ +LGN+LV A+ R LR TN FIVSLA +DL V++LVMP+ A
Sbjct: 40 QVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKA 99
Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
+ V W +G FC V + D++ +TASI +LC IS+DRY+AI +P Y+ KMT
Sbjct: 100 VAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAI-SRPFRYKRKMTQRMA 157
Query: 139 ALMLGGCWVIPTFISFLPIMQGW--------------NNIGIIDLIEKRKFNQNSNSTYC 184
+M+G W + ISF+P+ W NN+ E+ + + N+ C
Sbjct: 158 LVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENC 217
Query: 185 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSA- 243
+N+ YAI+ S+++FYIP +M++ Y RIY A+ +I L+RA ++S SA
Sbjct: 218 DSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAA 277
Query: 244 ---DQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG--------- 291
D ++ ETK KTL +IMG F CW PFF+ N + PF G
Sbjct: 278 CAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVS 337
Query: 292 -QVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRP 337
+ F+W G+ NS LNP +YAF N F++ F +L C R P
Sbjct: 338 ETTFDVFVWFGWANSSLNPVIYAF-NADFQKVFAQLLGCSHFCSRTP 383
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 209 bits (531), Expect = 4e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
Query: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
Query: 318 SFRRAFLIILCC 329
FR + + CC
Sbjct: 294 DFRTGYQQLFCC 305
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 209 bits (531), Expect = 4e-54
Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)
Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
K+ + L+ +IL+ + GN++V +AV +R+LR + TN FIVSLA DLL+ +LV+PF A
Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76
Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
I + W +G+VFC + TSLDV+L TASI +L ISLDRY A+ PL Y +TP+R+
Sbjct: 77 IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135
Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
A+ L WVI +SFL I GWN+ N ++ C VN+ Y + +
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188
Query: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
V FY+P L+M + YYRI+ A++ A +I + S+ + +T R E KA
Sbjct: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233
Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
TL +MG F +CW P+F + +V A LWLGY NS LNP LYA LN+
Sbjct: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293
Query: 318 SFRRAFLIILCC 329
FR + + CC
Sbjct: 294 DFRTGYQQLFCC 305
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 207 bits (527), Expect = 1e-53
Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)
Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P
Sbjct: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
++MV Y R++ AK +I + D + H +R E KA
Sbjct: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272
Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y +
Sbjct: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331
Query: 319 FRRAFLIILC 328
FR AF +LC
Sbjct: 332 FRIAFQELLC 341
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 204 bits (519), Expect = 1e-52
Identities = 111/306 (36%), Positives = 169/306 (55%), Gaps = 12/306 (3%)
Query: 22 LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81
L + + +IL ++GNL+V+V++ +QL TN+ I S+A D L+ LVMP+ +
Sbjct: 26 LYSLMVLIILTTLVGNLIVIVSISHFKQLHT-PTNWLIHSMATVDFLLGCLVMPYSMVRS 84
Query: 82 VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141
+ W +GEVFC + TS D++L++ASIFHL IS+DRYYA+C PL Y+ KM L I +M
Sbjct: 85 AEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVC-DPLRYKAKMNILVICVM 143
Query: 142 LGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAF 201
+ W +P +F I N G ++ K + C +K + + +F
Sbjct: 144 IFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGG----CSVFFSKISGVLTFMTSF 199
Query: 202 YIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTL 261
YIP +M+ YYRIY+ AKE A I +++ + + E KA KTL
Sbjct: 200 YIPGSIMLCVYYRIYLIAKEQARLIS------DANQKLQIGLEMKNGISQSKERKAVKTL 253
Query: 262 CIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRR 321
I+MG F +CW PFF+ ++DPF+ Y +P + +W GY+NS NP +YAF FR+
Sbjct: 254 GIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRK 313
Query: 322 AFLIIL 327
A ++L
Sbjct: 314 ALKMML 319
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 201 bits (511), Expect = 8e-52
Identities = 126/344 (36%), Positives = 181/344 (52%), Gaps = 41/344 (11%)
Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
++ ++L+ + GN+LV+VA+ +L+ + TN FI+SLA ADL++ +LV+PFGA +V
Sbjct: 65 MALIVLLIVAGNVLVIVAIAKTPRLQTL-TNLFIMSLASADLVMGLLVVPFGATIVVWGR 123
Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
W YG FC + TS+DVL TASI LC I+LDRY AI P Y++ +T R ++
Sbjct: 124 WEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAI-TSPFRYQSLLTRARARGLVCTV 182
Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
W I +SFLPI+ W + +R +N + C F+ N+ YAI SVV+FY+P
Sbjct: 183 WAISALVSFLPILMHWWRAESDE--ARRCYN---DPKCCDFVTNRAYAIASSVVSFYVPL 237
Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS----------------------- 242
+M Y R++ A++ +I +R +RP S
Sbjct: 238 CIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAA 297
Query: 243 --------ADQHSTHRM--RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292
A + R+ E KA KTL IIMG F LCW PFF+ N+V F VP +
Sbjct: 298 TAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDR 357
Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
++ F WLGY NS NP +Y + FR+AF +LCC RR
Sbjct: 358 LFVFFNWLGYANSAFNPIIYC-RSPDFRKAFQGLLCCARRAARR 400
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 195 bits (495), Expect = 6e-50
Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%)
Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
+G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+ +NY IVSLA ADL V+V V
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134
Query: 74 MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
MPF ++ +L+ WI+G FC V ++DV+ TASI LC IS+DRY I +PL Y +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193
Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192
+A M+ W++ I+ LP + GW N N + C+ + Y
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239
Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237
I + VAFYIP +M+ YY+IY A++ A H+ R S
Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299
Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288
SR ++ + + E KAA TL II+G F +CW PFF+ + PFI T
Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359
Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
+P V FLWLGY NS +NPF+YAF N+ R + +L C R
Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 195 bits (495), Expect = 6e-50
Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%)
Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
+G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+ +NY IVSLA ADL V+V V
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134
Query: 74 MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
MPF ++ +L+ WI+G FC V ++DV+ TASI LC IS+DRY I +PL Y +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193
Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192
+A M+ W++ I+ LP + GW N N + C+ + Y
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239
Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237
I + VAFYIP +M+ YY+IY A++ A H+ R S
Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299
Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288
SR ++ + + E KAA TL II+G F +CW PFF+ + PFI T
Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359
Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
+P V FLWLGY NS +NPF+YAF N+ R + +L C R
Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 195 bits (495), Expect = 6e-50
Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%)
Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
+G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+ +NY IVSLA ADL V+V V
Sbjct: 76 YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134
Query: 74 MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
MPF ++ +L+ WI+G FC V ++DV+ TASI LC IS+DRY I +PL Y +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193
Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192
+A M+ W++ I+ LP + GW N N + C+ + Y
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239
Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237
I + VAFYIP +M+ YY+IY A++ A H+ R S
Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299
Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288
SR ++ + + E KAA TL II+G F +CW PFF+ + PFI T
Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359
Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
+P V FLWLGY NS +NPF+YAF N+ R + +L C R
Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408
>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
sapiens]
Length = 351
Score = 192 bits (489), Expect = 3e-49
Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)
Query: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
+V + +F++ I + I GNL +++++ + +QL TN+ I+S+A D L+ +MP+
Sbjct: 43 RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101
Query: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
I V++ W +G FC + S D++L+ SIFHLC +++DR+YAIC PL+Y K+T I
Sbjct: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160
Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196
+L CW +P +F + GI D++ + S+ C M NK + T
Sbjct: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213
Query: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256
+ F+ P +MV Y +I+ +++HAH I L+ ++ ++++ + K
Sbjct: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259
Query: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316
AAKTL I++G F LCW P F T ++DPF++++ P ++ A W GY NS NP +Y F
Sbjct: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319
Query: 317 KSFRRAFLIIL 327
FRRA IL
Sbjct: 320 PWFRRALKYIL 330
>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
sapiens]
Length = 306
Score = 190 bits (483), Expect = 1e-48
Identities = 104/308 (33%), Positives = 171/308 (55%), Gaps = 25/308 (8%)
Query: 22 LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81
+ +F++ I + I GNL +++++ + +QL TN+ I+S+A D L+ +MP+ I
Sbjct: 1 MYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSMIRS 59
Query: 82 VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141
V++ W +G FC + S D++L+ SIFHLC +++DR+YAIC PL+Y K+T I +
Sbjct: 60 VENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVIKRL 118
Query: 142 LGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVV 199
L CW +P +F + GI D++ + S+ C M NK + T +
Sbjct: 119 LLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTLFMA 171
Query: 200 AFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAK 259
F+ P +MV Y +I+ +++HAH I L+ ++ ++++ + KAAK
Sbjct: 172 GFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKKAAK 217
Query: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
TL I++G F LCW P F T ++DPF++++ P ++ A W GY NS NP +Y F F
Sbjct: 218 TLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWF 277
Query: 320 RRAFLIIL 327
RRA IL
Sbjct: 278 RRALKYIL 285
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 187 bits (476), Expect = 1e-47
Identities = 124/349 (35%), Positives = 176/349 (50%), Gaps = 43/349 (12%)
Query: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
S + V + FL+ ILMA+ GNLLV+++V +R L+ + TNYFIV+LA ADLL+S V+P
Sbjct: 93 SAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTV-TNYFIVNLAVADLLLSATVLP 151
Query: 76 FGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTP 135
F A V W +G FC V ++DVL TASI LC IS+DRY + L Y MT
Sbjct: 152 FSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGV-RHSLKYPAIMTE 210
Query: 136 LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAIT 195
+ A +L WV+ +S P++ GW K + +C YA+
Sbjct: 211 RKAAAILALLWVVALVVSVGPLL-GW------------KEPVPPDERFCGITEEAGYAVF 257
Query: 196 CSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE------SRPQSADQHS 247
SV +FY+P ++V+ Y R+YV A+ ++ + + G +SE R +
Sbjct: 258 SSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADG 317
Query: 248 THRMRT-------------------ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT 288
H MR+ E KAAKTL I++G F LCW PFF +
Sbjct: 318 AHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQL 377
Query: 289 VPGQ-VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
P + V+ WLGY NS +NP +Y ++ F+RAFL +L C R RR
Sbjct: 378 KPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR 426
>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
Length = 345
Score = 178 bits (452), Expect = 6e-45
Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)
Query: 14 FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
F +V+L ++A+ GNLLVM+++ +QL TN+ + SLA AD LV V V
Sbjct: 27 FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85
Query: 74 MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
MPF + V+ W +G FC T DV +S+FHLC IS+DRY A+ PLVY K
Sbjct: 86 MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144
Query: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
T + + W++P S G + G+ +L + C +VN+ +
Sbjct: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199
Query: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
+T ++F+IP +M++ Y I++ A+ A +I + G+ +ES S++ + R
Sbjct: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252
Query: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
E KAAKTL + + F + W P+ + +++D F+ + P ++ W Y NS +NP +YA
Sbjct: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312
Query: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
FR+A +I + GQ + S+ T+N
Sbjct: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 177 bits (450), Expect = 1e-44
Identities = 117/329 (35%), Positives = 166/329 (50%), Gaps = 40/329 (12%)
Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
L IL AI+GN+LV+++V +R LR TNYFIV+LA ADLL+S V+PF A V
Sbjct: 52 LGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTVLPFSAALEVLGY 110
Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
W+ G +FC + ++DVL TASI LC IS+DRY + L Y +T + L L
Sbjct: 111 WVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGV-RYSLQYPTLVTRRKAILALLSV 169
Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
WV+ T IS P++ GW K ++ C YA+ S+ +FYIP
Sbjct: 170 WVLSTVISIGPLL-GW------------KEPAPNDDKECGVTEEPFYALFSSLGSFYIPL 216
Query: 206 LLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE----------------------SRPQ 241
++++ Y R+Y+ AK ++ +++ S E P+
Sbjct: 217 AVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPR 276
Query: 242 SADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVT-NIVDPFIDYTVPGQVWTAFLWL 300
S+ + E KAAKTL I++G F LCW PFF+ + F P V+ WL
Sbjct: 277 SSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWL 336
Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCC 329
GY NS LNP +Y +K F+RAF+ IL C
Sbjct: 337 GYFNSCLNPIIYPCSSKEFKRAFVRILGC 365
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 177 bits (448), Expect = 2e-44
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)
Query: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
+L L ++A GNLLVM+A+ +QL TN+ I SLA AD LV V VMPF +
Sbjct: 34 ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92
Query: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
V+ W +G+ +C T D AS+FHLCCIS+DRY A+ PL Y K T +
Sbjct: 93 SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151
Query: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
+ W SF G N GI +L+ C +N+ + + C ++
Sbjct: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205
Query: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
F+IP + MV Y +I++ AK A +I+ S+ S+ QS+ + R+ + E KAAK
Sbjct: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258
Query: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
TL I M F + W P+ V ++D ++++ P V+ +W Y NS +NP +YAF + F
Sbjct: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318
Query: 320 RRAFLIIL 327
+A +I+
Sbjct: 319 GKAIKLIV 326
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 174 bits (442), Expect = 8e-44
Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)
Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+
Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80
Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139
Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
R + L W + IS P+ GW D T C Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186
Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
++ +FY+P ++++ Y R+YV AK + ++ + R A +
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246
Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306
Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
V+ WLGY+NS +NP +Y ++ F++AF +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 174 bits (442), Expect = 8e-44
Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)
Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+
Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80
Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139
Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
R + L W + IS P+ GW D T C Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186
Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
++ +FY+P ++++ Y R+YV AK + ++ + R A +
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246
Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306
Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
V+ WLGY+NS +NP +Y ++ F++AF +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 174 bits (442), Expect = 8e-44
Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)
Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+
Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80
Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139
Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
R + L W + IS P+ GW D T C Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186
Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
++ +FY+P ++++ Y R+YV AK + ++ + R A +
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246
Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306
Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
V+ WLGY+NS +NP +Y ++ F++AF +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 174 bits (442), Expect = 8e-44
Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)
Query: 16 SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
++ K +LL L +IL +LGN+LV+++V R L + T+Y+IV+LA ADLL++ V+
Sbjct: 22 NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80
Query: 75 PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
PF AI V W +G VFC + ++DVL TASI LC IS+DRY + PL Y +T
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139
Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
R + L W + IS P+ GW D T C Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186
Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
++ +FY+P ++++ Y R+YV AK + ++ + R A +
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246
Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
++ + TH + E KAAKTL I++GCF LCW PFF+ + F D+
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306
Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
V+ WLGY+NS +NP +Y ++ F++AF +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 174 bits (440), Expect = 1e-43
Identities = 108/317 (34%), Positives = 161/317 (50%), Gaps = 25/317 (7%)
Query: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
L VI + N L++ +C LR +N+F+VSL +DL+V ++VMP + +
Sbjct: 33 LCVVIALTAAANSLLIALICTQPALRNT-SNFFLVSLFTSDLMVGLVVMPPAMLNALYGR 91
Query: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
W+ CL+ T+ DV+ +ASI +LC ISLDRY I PL Y+ +MTPLR ++ G
Sbjct: 92 WVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLI-LSPLRYKLRMTPLRALALVLGA 150
Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
W + SFLP++ GW+ +G + C + + P+ + S + F++P
Sbjct: 151 WSLAALASFLPLLLGWHELG---------HARPPVPGQCRLLASLPFVLVASGLTFFLPS 201
Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES---------RP--QSADQH--STHRMR 252
+ Y RI + A++ A Q+ L AS S RP +SAD +T R
Sbjct: 202 GAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSR 261
Query: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
KA+ TL I++G F + W PFFV NIV D PG ++ WLGY NS +NP +Y
Sbjct: 262 KALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG-LFDVLTWLGYCNSTMNPIIY 320
Query: 313 AFLNKSFRRAFLIILCC 329
+ F+RA L C
Sbjct: 321 PLFMRDFKRALGRFLPC 337
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 171 bits (432), Expect = 1e-42
Identities = 124/380 (32%), Positives = 182/380 (47%), Gaps = 42/380 (11%)
Query: 4 LDANVSSEEGFGSV--EKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVS 61
L N ++ G V E + L+ +L + GNLLV+VA+ W +L+ + TN F+ S
Sbjct: 20 LAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTM-TNVFVTS 78
Query: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121
LA ADL++ +LV+P A + W G C + TS+DVL TASI LC +++DRY A
Sbjct: 79 LAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLA 138
Query: 122 ICCQPLVYRNKMTP--LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNS 179
+ PL Y +T R A++L WV+ +SF PIM W +G + +S
Sbjct: 139 V-TNPLRYGALVTKRCARTAVVL--VWVVSAAVSFAPIMSQWWRVG----ADAEAQRCHS 191
Query: 180 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 239
N C F N PY + S V+FY+P L+M+ Y R++V A ++ ES
Sbjct: 192 NPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESP 251
Query: 240 PQSADQHSTHRMRT---------------------ETKAAKTLCIIMGCFCLCWAPFFVT 278
P + + + T E +A TL +IMG F LCW PFF+
Sbjct: 252 PAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLA 311
Query: 279 NIVDPFIDYT-VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERY--- 334
N++ + VPG + A WLGY NS NP +Y + FR AF +LC R
Sbjct: 312 NVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYC-RSPDFRSAFRRLLCRCGRRLPPE 370
Query: 335 ----RRPSILGQTVPCSTTT 350
RP++ VP + ++
Sbjct: 371 PCAAARPALFPSGVPAARSS 390
>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
Length = 342
Score = 170 bits (430), Expect = 2e-42
Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%)
Query: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70
E + +V+L T S L+A+ GNLLVM +V +QL TN+ I SLA AD LV
Sbjct: 23 ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81
Query: 71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
V VM F + V+ W +G FC + + DV +S+ HLC I +DRY + PLVY
Sbjct: 82 VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140
Query: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190
K T + + W++P S G N+ G+ +L+ C +V++
Sbjct: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195
Query: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250
+ + + F+IP L+M++ Y +I++ AK+ A +I+ +S S++ +
Sbjct: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248
Query: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310
+ E KAAKTL + + F + W P+ V ++D F+ + P ++ W Y NS +NP
Sbjct: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308
Query: 311 LYAFLNKSFRRAFLIILCCD 330
+YA FR+A +IL D
Sbjct: 309 IYALFYPWFRKAIKLILSGD 328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.141 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,969,175
Number of Sequences: 37866
Number of extensions: 475810
Number of successful extensions: 3345
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 337
Number of HSP's successfully gapped in prelim test: 343
Number of HSP's that attempted gapping in prelim test: 1815
Number of HSP's gapped (non-prelim): 1006
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.