Search of human proteins with 94421460

Search of human proteins with 94421460

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
         (428 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]         879   0.0  
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]         778   0.0  
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]        768   0.0  
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]         734   0.0  
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]         734   0.0  
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]         734   0.0  
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]         732   0.0  
gi|4503383 dopamine receptor D1 [Homo sapiens]                        219   3e-57
gi|4503391 dopamine receptor D5 [Homo sapiens]                        216   4e-56
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]           209   5e-54
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]            209   5e-54
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]      207   1e-53
gi|21264324 trace amine associated receptor 1 [Homo sapiens]          204   1e-52
gi|4557265 beta-1-adrenergic receptor [Homo sapiens]                  201   1e-51
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]   195   8e-50
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]   195   8e-50
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]    195   8e-50
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa...   192   4e-49
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa...   190   2e-48
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                187   1e-47
gi|28173558 trace amine associated receptor 6 [Homo sapiens]          178   7e-45
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                177   1e-44
gi|110618256 trace amine associated receptor 9 [Homo sapiens]         177   2e-44
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]    174   1e-43
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]    174   1e-43
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]    174   1e-43
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]    174   1e-43
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...   174   2e-43
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]               171   2e-42
gi|16751917 trace amine associated receptor 8 [Homo sapiens]          170   3e-42

>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score =  879 bits (2272), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180

Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
           STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240

Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
           QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300

Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRT 360
           GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRT
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRT 360

Query: 361 DFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGGQWESQCHPPATSPL 420
           DFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGGQWESQCHPPATSPL
Sbjct: 361 DFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGGQWESQCHPPATSPL 420

Query: 421 VAAQPSDT 428
           VAAQPSDT
Sbjct: 421 VAAQPSDT 428


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score =  778 bits (2008), Expect = 0.0
 Identities = 388/428 (90%), Positives = 388/428 (90%), Gaps = 40/428 (9%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180

Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
           STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240

Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
           QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300

Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRT 360
           GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR- 359

Query: 361 DFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGGQWESQCHPPATSPL 420
                                                  DAVECGGQWESQCHPPATSPL
Sbjct: 360 ---------------------------------------DAVECGGQWESQCHPPATSPL 380

Query: 421 VAAQPSDT 428
           VAAQPSDT
Sbjct: 381 VAAQPSDT 388


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score =  768 bits (1983), Expect = 0.0
 Identities = 388/442 (87%), Positives = 388/442 (87%), Gaps = 54/442 (12%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL----------- 169
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDL           
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQD 180

Query: 170 ---IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 226
              IEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI
Sbjct: 181 FHAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI 240

Query: 227 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 286
           QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID
Sbjct: 241 QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFID 300

Query: 287 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 346
           YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC
Sbjct: 301 YTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPC 360

Query: 347 STTTINGSTHVLRTDFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGG 406
           STTTINGSTHVLR                                        DAVECGG
Sbjct: 361 STTTINGSTHVLR----------------------------------------DAVECGG 380

Query: 407 QWESQCHPPATSPLVAAQPSDT 428
           QWESQCHPPATSPLVAAQPSDT
Sbjct: 381 QWESQCHPPATSPLVAAQPSDT 402


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score =  734 bits (1895), Expect = 0.0
 Identities = 359/359 (100%), Positives = 359/359 (100%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180

Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
           STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240

Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
           QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300

Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
           GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score =  734 bits (1895), Expect = 0.0
 Identities = 359/359 (100%), Positives = 359/359 (100%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180

Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
           STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240

Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
           QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300

Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
           GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score =  734 bits (1895), Expect = 0.0
 Identities = 359/359 (100%), Positives = 359/359 (100%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180

Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
           STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240

Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
           QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300

Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359
           GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLR 359


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score =  732 bits (1890), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
Sbjct: 1   MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
Sbjct: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
           AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
Sbjct: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180

Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240
           STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
Sbjct: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 240

Query: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300
           QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
Sbjct: 241 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 300

Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358
           GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVL 358


>gi|4503383 dopamine receptor D1 [Homo sapiens]
          Length = 446

 Score =  219 bits (559), Expect = 3e-57
 Identities = 127/349 (36%), Positives = 190/349 (54%), Gaps = 32/349 (9%)

Query: 7   NVSSEEGFGSVE------KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 60
           N S+ +G G V       +++   FLS +IL  +LGN LV  AV   R LR   TN+F++
Sbjct: 5   NTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVI 64

Query: 61  SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 120
           SLA +DLLV+VLVMP+ A+  +   W +G  FC +  + D++ +TASI +LC IS+DRY+
Sbjct: 65  SLAVSDLLVAVLVMPWKAVAEIAGFWPFGS-FCNIWVAFDIMCSTASILNLCVISVDRYW 123

Query: 121 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 180
           AI   P  Y  KMTP    +++   W +   ISF+P+   W+        +    +    
Sbjct: 124 AI-SSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAET 182

Query: 181 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSE--- 237
              C   +++ YAI+ SV++FYIP  +M++ Y RIY  A++   +I  L+RA   ++   
Sbjct: 183 IDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQ 242

Query: 238 -----------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI- 285
                      S+P+S+ + S  R   ETK  KTL +IMG F  CW PFF+ N + PF  
Sbjct: 243 TTTGNGKPVECSQPESSFKMSFKR---ETKVLKTLSVIMGVFVCCWLPFFILNCILPFCG 299

Query: 286 -----DYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC 329
                 + +    +  F+W G+ NS LNP +YAF N  FR+AF  +L C
Sbjct: 300 SGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAF-NADFRKAFSTLLGC 347


>gi|4503391 dopamine receptor D5 [Homo sapiens]
          Length = 477

 Score =  216 bits (549), Expect = 4e-56
 Identities = 134/382 (35%), Positives = 196/382 (51%), Gaps = 39/382 (10%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           +VV    L+ +I+  +LGN+LV  A+   R LR   TN FIVSLA +DL V++LVMP+ A
Sbjct: 40  QVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKA 99

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           +  V   W +G  FC V  + D++ +TASI +LC IS+DRY+AI  +P  Y+ KMT    
Sbjct: 100 VAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAI-SRPFRYKRKMTQRMA 157

Query: 139 ALMLGGCWVIPTFISFLPIMQGW--------------NNIGIIDLIEKRKFNQNSNSTYC 184
            +M+G  W +   ISF+P+   W              NN+      E+  +  + N+  C
Sbjct: 158 LVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENC 217

Query: 185 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSA- 243
              +N+ YAI+ S+++FYIP  +M++ Y RIY  A+    +I  L+RA   ++S   SA 
Sbjct: 218 DSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAA 277

Query: 244 ---DQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG--------- 291
              D      ++ ETK  KTL +IMG F  CW PFF+ N + PF      G         
Sbjct: 278 CAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVS 337

Query: 292 -QVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTT 350
              +  F+W G+ NS LNP +YAF N  F++ F  +L C        S      P  T  
Sbjct: 338 ETTFDVFVWFGWANSSLNPVIYAF-NADFQKVFAQLLGC--------SHFCSRTPVETVN 388

Query: 351 INGSTHVLRTDFLFDRDILARY 372
           I+        D +F ++I A Y
Sbjct: 389 ISNELISYNQDIVFHKEIAAAY 410


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score =  209 bits (531), Expect = 5e-54
 Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           K+ +   L+ +IL+ + GN++V +AV  +R+LR + TN FIVSLA  DLL+ +LV+PF A
Sbjct: 18  KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           I  +   W +G+VFC + TSLDV+L TASI +L  ISLDRY A+   PL Y   +TP+R+
Sbjct: 77  IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135

Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
           A+ L   WVI   +SFL I  GWN+              N  ++ C   VN+ Y +   +
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188

Query: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
           V FY+P L+M + YYRI+  A++ A +I  +            S+ + +T R   E KA 
Sbjct: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233

Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
            TL  +MG F +CW P+F   +           +V  A  LWLGY NS LNP LYA LN+
Sbjct: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293

Query: 318 SFRRAFLIILCC 329
            FR  +  + CC
Sbjct: 294 DFRTGYQQLFCC 305


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score =  209 bits (531), Expect = 5e-54
 Identities = 124/312 (39%), Positives = 176/312 (56%), Gaps = 25/312 (8%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           K+ +   L+ +IL+ + GN++V +AV  +R+LR + TN FIVSLA  DLL+ +LV+PF A
Sbjct: 18  KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPFSA 76

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           I  +   W +G+VFC + TSLDV+L TASI +L  ISLDRY A+   PL Y   +TP+R+
Sbjct: 77  IYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV-MDPLRYPVLVTPVRV 135

Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
           A+ L   WVI   +SFL I  GWN+              N  ++ C   VN+ Y +   +
Sbjct: 136 AISLVLIWVISITLSFLSIHLGWNS-------RNETSKGNHTTSKCKVQVNEVYGLVDGL 188

Query: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAA 258
           V FY+P L+M + YYRI+  A++ A +I  +            S+ + +T R   E KA 
Sbjct: 189 VTFYLPLLIMCITYYRIFKVARDQAKRINHI------------SSWKAATIR---EHKAT 233

Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAF-LWLGYINSGLNPFLYAFLNK 317
            TL  +MG F +CW P+F   +           +V  A  LWLGY NS LNP LYA LN+
Sbjct: 234 VTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNR 293

Query: 318 SFRRAFLIILCC 329
            FR  +  + CC
Sbjct: 294 DFRTGYQQLFCC 305


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score =  207 bits (527), Expect = 1e-53
 Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           +S ++L  + GN+LV+ A+    +L+ + TNYFI SLA ADL++ + V+PFGA  ++  +
Sbjct: 40  MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W +G  +C   TS+DVL  TASI  LC I++DRY+AI   P  Y++ +T  +  +++   
Sbjct: 99  WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
           W++    SFLPI   W          +   N  +N T C F  N+ YAI  S+V+FY+P 
Sbjct: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212

Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
           ++MV  Y R++  AK    +I   +             D  + H +R        E KA 
Sbjct: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272

Query: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
           KTL IIMG F LCW PFF+ NIV    D  +  +V+    W+GY+NSG NP +Y   +  
Sbjct: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331

Query: 319 FRRAFLIILC 328
           FR AF  +LC
Sbjct: 332 FRIAFQELLC 341


>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
          Length = 339

 Score =  204 bits (519), Expect = 1e-52
 Identities = 111/306 (36%), Positives = 169/306 (55%), Gaps = 12/306 (3%)

Query: 22  LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81
           L + +  +IL  ++GNL+V+V++   +QL    TN+ I S+A  D L+  LVMP+  +  
Sbjct: 26  LYSLMVLIILTTLVGNLIVIVSISHFKQLHT-PTNWLIHSMATVDFLLGCLVMPYSMVRS 84

Query: 82  VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141
            +  W +GEVFC + TS D++L++ASIFHL  IS+DRYYA+C  PL Y+ KM  L I +M
Sbjct: 85  AEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVC-DPLRYKAKMNILVICVM 143

Query: 142 LGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAF 201
           +   W +P   +F  I    N  G  ++  K    +      C    +K   +   + +F
Sbjct: 144 IFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGG----CSVFFSKISGVLTFMTSF 199

Query: 202 YIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTL 261
           YIP  +M+  YYRIY+ AKE A  I        +++      +  +      E KA KTL
Sbjct: 200 YIPGSIMLCVYYRIYLIAKEQARLIS------DANQKLQIGLEMKNGISQSKERKAVKTL 253

Query: 262 CIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRR 321
            I+MG F +CW PFF+  ++DPF+ Y +P  +    +W GY+NS  NP +YAF    FR+
Sbjct: 254 GIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRK 313

Query: 322 AFLIIL 327
           A  ++L
Sbjct: 314 ALKMML 319


>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
          Length = 477

 Score =  201 bits (511), Expect = 1e-51
 Identities = 126/344 (36%), Positives = 181/344 (52%), Gaps = 41/344 (11%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           ++ ++L+ + GN+LV+VA+    +L+ + TN FI+SLA ADL++ +LV+PFGA  +V   
Sbjct: 65  MALIVLLIVAGNVLVIVAIAKTPRLQTL-TNLFIMSLASADLVMGLLVVPFGATIVVWGR 123

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W YG  FC + TS+DVL  TASI  LC I+LDRY AI   P  Y++ +T  R   ++   
Sbjct: 124 WEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAI-TSPFRYQSLLTRARARGLVCTV 182

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
           W I   +SFLPI+  W      +   +R +N   +   C F+ N+ YAI  SVV+FY+P 
Sbjct: 183 WAISALVSFLPILMHWWRAESDE--ARRCYN---DPKCCDFVTNRAYAIASSVVSFYVPL 237

Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS----------------------- 242
            +M   Y R++  A++   +I   +R      +RP S                       
Sbjct: 238 CIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAA 297

Query: 243 --------ADQHSTHRM--RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292
                   A +    R+    E KA KTL IIMG F LCW PFF+ N+V  F    VP +
Sbjct: 298 TAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDR 357

Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
           ++  F WLGY NS  NP +Y   +  FR+AF  +LCC     RR
Sbjct: 358 LFVFFNWLGYANSAFNPIIYC-RSPDFRKAFQGLLCCARRAARR 400


>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
          Length = 432

 Score =  195 bits (495), Expect = 8e-50
 Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+  +NY IVSLA ADL V+V V
Sbjct: 76  YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134

Query: 74  MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
           MPF ++ +L+   WI+G  FC V  ++DV+  TASI  LC IS+DRY  I  +PL Y  +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193

Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192
                +A M+   W++   I+ LP + GW              N N +   C+   +  Y
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239

Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237
            I  + VAFYIP  +M+  YY+IY  A++ A  H+     R    S              
Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299

Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288
                 SR    ++ +    + E KAA TL II+G F +CW PFF+ +   PFI  T   
Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359

Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
            +P  V   FLWLGY NS +NPF+YAF N+  R  +  +L C      R
Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408


>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
          Length = 479

 Score =  195 bits (495), Expect = 8e-50
 Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+  +NY IVSLA ADL V+V V
Sbjct: 76  YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134

Query: 74  MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
           MPF ++ +L+   WI+G  FC V  ++DV+  TASI  LC IS+DRY  I  +PL Y  +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193

Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192
                +A M+   W++   I+ LP + GW              N N +   C+   +  Y
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239

Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237
            I  + VAFYIP  +M+  YY+IY  A++ A  H+     R    S              
Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299

Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288
                 SR    ++ +    + E KAA TL II+G F +CW PFF+ +   PFI  T   
Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359

Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
            +P  V   FLWLGY NS +NPF+YAF N+  R  +  +L C      R
Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408


>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
          Length = 445

 Score =  195 bits (495), Expect = 8e-50
 Identities = 128/349 (36%), Positives = 184/349 (52%), Gaps = 42/349 (12%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           +G VEKVV+ + L+ + L+ I GN LV+++VC+ ++LR+  +NY IVSLA ADL V+V V
Sbjct: 76  YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQ-PSNYLIVSLALADLSVAVAV 134

Query: 74  MPFGAI-ELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNK 132
           MPF ++ +L+   WI+G  FC V  ++DV+  TASI  LC IS+DRY  I  +PL Y  +
Sbjct: 135 MPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT-RPLTYPVR 193

Query: 133 MTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPY 192
                +A M+   W++   I+ LP + GW              N N +   C+   +  Y
Sbjct: 194 QNGKCMAKMILSVWLLSASIT-LPPLFGWAQ------------NVNDDKV-CLISQDFGY 239

Query: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHA--HQIQMLQRAGASSE------------- 237
            I  + VAFYIP  +M+  YY+IY  A++ A  H+     R    S              
Sbjct: 240 TIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEV 299

Query: 238 ------SRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT--- 288
                 SR    ++ +    + E KAA TL II+G F +CW PFF+ +   PFI  T   
Sbjct: 300 EECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCS 359

Query: 289 -VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
            +P  V   FLWLGY NS +NPF+YAF N+  R  +  +L C      R
Sbjct: 360 CIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR 408


>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
           sapiens]
          Length = 351

 Score =  192 bits (489), Expect = 4e-49
 Identities = 105/311 (33%), Positives = 173/311 (55%), Gaps = 25/311 (8%)

Query: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
           +V + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  
Sbjct: 43  RVAMYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSM 101

Query: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
           I  V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I
Sbjct: 102 IRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVI 160

Query: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITC 196
             +L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T 
Sbjct: 161 KRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTL 213

Query: 197 SVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETK 256
            +  F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + K
Sbjct: 214 FMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKK 259

Query: 257 AAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLN 316
           AAKTL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F  
Sbjct: 260 AAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFY 319

Query: 317 KSFRRAFLIIL 327
             FRRA   IL
Sbjct: 320 PWFRRALKYIL 330


>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
           sapiens]
          Length = 306

 Score =  190 bits (483), Expect = 2e-48
 Identities = 104/308 (33%), Positives = 171/308 (55%), Gaps = 25/308 (8%)

Query: 22  LLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIEL 81
           + +F++  I + I GNL +++++ + +QL    TN+ I+S+A  D L+   +MP+  I  
Sbjct: 1   MYSFMAGSIFITIFGNLAMIISISYFKQLHT-PTNFLILSMAITDFLLGFTIMPYSMIRS 59

Query: 82  VQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALM 141
           V++ W +G  FC +  S D++L+  SIFHLC +++DR+YAIC  PL+Y  K+T   I  +
Sbjct: 60  VENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAIC-YPLLYSTKITIPVIKRL 118

Query: 142 LGGCWVIPTFISFLPIMQGWNNIGI--IDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVV 199
           L  CW +P   +F  +       GI   D++        + S+ C  M NK +  T  + 
Sbjct: 119 LLLCWSVPGAFAFGVVFSEAYADGIEGYDILV-------ACSSSCPVMFNKLWGTTLFMA 171

Query: 200 AFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAK 259
            F+ P  +MV  Y +I+  +++HAH I  L+              ++  ++++ + KAAK
Sbjct: 172 GFFTPGSMMVGIYGKIFAVSRKHAHAINNLR--------------ENQNNQVKKDKKAAK 217

Query: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
           TL I++G F LCW P F T ++DPF++++ P  ++ A  W GY NS  NP +Y F    F
Sbjct: 218 TLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWF 277

Query: 320 RRAFLIIL 327
           RRA   IL
Sbjct: 278 RRALKYIL 285


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score =  187 bits (476), Expect = 1e-47
 Identities = 124/349 (35%), Positives = 176/349 (50%), Gaps = 43/349 (12%)

Query: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
           S + V +  FL+  ILMA+ GNLLV+++V  +R L+ + TNYFIV+LA ADLL+S  V+P
Sbjct: 93  SAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTV-TNYFIVNLAVADLLLSATVLP 151

Query: 76  FGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTP 135
           F A   V   W +G  FC V  ++DVL  TASI  LC IS+DRY  +    L Y   MT 
Sbjct: 152 FSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGV-RHSLKYPAIMTE 210

Query: 136 LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAIT 195
            + A +L   WV+   +S  P++ GW            K     +  +C       YA+ 
Sbjct: 211 RKAAAILALLWVVALVVSVGPLL-GW------------KEPVPPDERFCGITEEAGYAVF 257

Query: 196 CSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE------SRPQSADQHS 247
            SV +FY+P  ++V+ Y R+YV A+     ++  + +  G +SE       R  +     
Sbjct: 258 SSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADG 317

Query: 248 THRMRT-------------------ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT 288
            H MR+                   E KAAKTL I++G F LCW PFF    +       
Sbjct: 318 AHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQL 377

Query: 289 VPGQ-VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR 336
            P + V+    WLGY NS +NP +Y   ++ F+RAFL +L C   R RR
Sbjct: 378 KPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR 426


>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
          Length = 345

 Score =  178 bits (452), Expect = 7e-45
 Identities = 105/339 (30%), Positives = 171/339 (50%), Gaps = 26/339 (7%)

Query: 14  FGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLV 73
           F    +V+L        ++A+ GNLLVM+++   +QL    TN+ + SLA AD LV V V
Sbjct: 27  FSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHS-PTNFLVASLACADFLVGVTV 85

Query: 74  MPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKM 133
           MPF  +  V+  W +G  FC   T  DV    +S+FHLC IS+DRY A+   PLVY  K 
Sbjct: 86  MPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAV-TDPLVYPTKF 144

Query: 134 TPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYA 193
           T     + +   W++P   S      G  + G+ +L +            C  +VN+ + 
Sbjct: 145 TVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGG-----CQTVVNQNWV 199

Query: 194 ITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRT 253
           +T   ++F+IP  +M++ Y  I++ A+  A +I   +  G+ +ES   S++ +     R 
Sbjct: 200 LT-DFLSFFIPTFIMIILYGNIFLVARRQAKKI---ENTGSKTES---SSESYKARVARR 252

Query: 254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYA 313
           E KAAKTL + +  F + W P+ + +++D F+ +  P  ++    W  Y NS +NP +YA
Sbjct: 253 ERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYA 312

Query: 314 FLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTIN 352
                FR+A  +I            + GQ +  S+ T+N
Sbjct: 313 LFYPWFRKAIKVI------------VTGQVLKNSSATMN 339


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score =  177 bits (450), Expect = 1e-44
 Identities = 117/329 (35%), Positives = 166/329 (50%), Gaps = 40/329 (12%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           L   IL AI+GN+LV+++V  +R LR   TNYFIV+LA ADLL+S  V+PF A   V   
Sbjct: 52  LGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTVLPFSAALEVLGY 110

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W+ G +FC +  ++DVL  TASI  LC IS+DRY  +    L Y   +T  +  L L   
Sbjct: 111 WVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGV-RYSLQYPTLVTRRKAILALLSV 169

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
           WV+ T IS  P++ GW            K    ++   C       YA+  S+ +FYIP 
Sbjct: 170 WVLSTVISIGPLL-GW------------KEPAPNDDKECGVTEEPFYALFSSLGSFYIPL 216

Query: 206 LLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSE----------------------SRPQ 241
            ++++ Y R+Y+ AK     ++  +++    S E                        P+
Sbjct: 217 AVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPR 276

Query: 242 SADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVT-NIVDPFIDYTVPGQVWTAFLWL 300
           S+      +   E KAAKTL I++G F LCW PFF+   +   F     P  V+    WL
Sbjct: 277 SSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWL 336

Query: 301 GYINSGLNPFLYAFLNKSFRRAFLIILCC 329
           GY NS LNP +Y   +K F+RAF+ IL C
Sbjct: 337 GYFNSCLNPIIYPCSSKEFKRAFVRILGC 365


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score =  177 bits (448), Expect = 2e-44
 Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 16/308 (5%)

Query: 21  VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
           +L   L    ++A  GNLLVM+A+   +QL    TN+ I SLA AD LV V VMPF  + 
Sbjct: 34  ILYAVLGFGAVLAAFGNLLVMIAILHFKQLHT-PTNFLIASLACADFLVGVTVMPFSTVR 92

Query: 81  LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
            V+  W +G+ +C   T  D     AS+FHLCCIS+DRY A+   PL Y  K T     +
Sbjct: 93  SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAV-TDPLTYPTKFTVSVSGI 151

Query: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
            +   W      SF     G N  GI +L+             C   +N+ + + C ++ 
Sbjct: 152 CIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGG-----CQAPLNQNWVLLCFLL- 205

Query: 201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM-RTETKAAK 259
           F+IP + MV  Y +I++ AK  A +I+       S+ S+ QS+ +    R+ + E KAAK
Sbjct: 206 FFIPNVAMVFIYSKIFLVAKHQARKIE-------STASQAQSSSESYKERVAKRERKAAK 258

Query: 260 TLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSF 319
           TL I M  F + W P+ V  ++D ++++  P  V+   +W  Y NS +NP +YAF  + F
Sbjct: 259 TLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWF 318

Query: 320 RRAFLIIL 327
            +A  +I+
Sbjct: 319 GKAIKLIV 326


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score =  174 bits (442), Expect = 1e-43
 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)

Query: 16  SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
           ++ K +LL   L  +IL  +LGN+LV+++V   R L  + T+Y+IV+LA ADLL++  V+
Sbjct: 22  NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80

Query: 75  PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
           PF AI  V   W +G VFC +  ++DVL  TASI  LC IS+DRY  +   PL Y   +T
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139

Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
             R  + L   W +   IS  P+  GW      D             T C       Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186

Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
             ++ +FY+P  ++++ Y R+YV AK  +  ++                + R  A +   
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246

Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
             ++ +  TH      +   E KAAKTL I++GCF LCW PFF+   +  F  D+     
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306

Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
           V+    WLGY+NS +NP +Y   ++ F++AF  +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score =  174 bits (442), Expect = 1e-43
 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)

Query: 16  SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
           ++ K +LL   L  +IL  +LGN+LV+++V   R L  + T+Y+IV+LA ADLL++  V+
Sbjct: 22  NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80

Query: 75  PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
           PF AI  V   W +G VFC +  ++DVL  TASI  LC IS+DRY  +   PL Y   +T
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139

Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
             R  + L   W +   IS  P+  GW      D             T C       Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186

Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
             ++ +FY+P  ++++ Y R+YV AK  +  ++                + R  A +   
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246

Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
             ++ +  TH      +   E KAAKTL I++GCF LCW PFF+   +  F  D+     
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306

Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
           V+    WLGY+NS +NP +Y   ++ F++AF  +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score =  174 bits (442), Expect = 1e-43
 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)

Query: 16  SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
           ++ K +LL   L  +IL  +LGN+LV+++V   R L  + T+Y+IV+LA ADLL++  V+
Sbjct: 22  NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80

Query: 75  PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
           PF AI  V   W +G VFC +  ++DVL  TASI  LC IS+DRY  +   PL Y   +T
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139

Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
             R  + L   W +   IS  P+  GW      D             T C       Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186

Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
             ++ +FY+P  ++++ Y R+YV AK  +  ++                + R  A +   
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246

Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
             ++ +  TH      +   E KAAKTL I++GCF LCW PFF+   +  F  D+     
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306

Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
           V+    WLGY+NS +NP +Y   ++ F++AF  +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score =  174 bits (442), Expect = 1e-43
 Identities = 111/335 (33%), Positives = 170/335 (50%), Gaps = 38/335 (11%)

Query: 16  SVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVM 74
           ++ K +LL   L  +IL  +LGN+LV+++V   R L  + T+Y+IV+LA ADLL++  V+
Sbjct: 22  NISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV-THYYIVNLAVADLLLTSTVL 80

Query: 75  PFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
           PF AI  V   W +G VFC +  ++DVL  TASI  LC IS+DRY  +   PL Y   +T
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGV-SYPLRYPTIVT 139

Query: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194
             R  + L   W +   IS  P+  GW      D             T C       Y +
Sbjct: 140 QRRGLMALLCVWALSLVISIGPLF-GWRQPAPED------------ETICQINEEPGYVL 186

Query: 195 TCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ---------------MLQRAGASSESR 239
             ++ +FY+P  ++++ Y R+YV AK  +  ++                + R  A +   
Sbjct: 187 FSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGS 246

Query: 240 PQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQ 292
             ++ +  TH      +   E KAAKTL I++GCF LCW PFF+   +  F  D+     
Sbjct: 247 GMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSET 306

Query: 293 VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327
           V+    WLGY+NS +NP +Y   ++ F++AF  +L
Sbjct: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score =  174 bits (440), Expect = 2e-43
 Identities = 108/317 (34%), Positives = 161/317 (50%), Gaps = 25/317 (7%)

Query: 26  LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
           L  VI +    N L++  +C    LR   +N+F+VSL  +DL+V ++VMP   +  +   
Sbjct: 33  LCVVIALTAAANSLLIALICTQPALRNT-SNFFLVSLFTSDLMVGLVVMPPAMLNALYGR 91

Query: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
           W+     CL+ T+ DV+  +ASI +LC ISLDRY  I   PL Y+ +MTPLR   ++ G 
Sbjct: 92  WVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLI-LSPLRYKLRMTPLRALALVLGA 150

Query: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
           W +    SFLP++ GW+ +G           +      C  + + P+ +  S + F++P 
Sbjct: 151 WSLAALASFLPLLLGWHELG---------HARPPVPGQCRLLASLPFVLVASGLTFFLPS 201

Query: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES---------RP--QSADQH--STHRMR 252
             +   Y RI + A++ A Q+  L    AS  S         RP  +SAD    +T   R
Sbjct: 202 GAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSR 261

Query: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
              KA+ TL I++G F + W PFFV NIV    D   PG ++    WLGY NS +NP +Y
Sbjct: 262 KALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG-LFDVLTWLGYCNSTMNPIIY 320

Query: 313 AFLNKSFRRAFLIILCC 329
               + F+RA    L C
Sbjct: 321 PLFMRDFKRALGRFLPC 337


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score =  171 bits (432), Expect = 2e-42
 Identities = 124/380 (32%), Positives = 182/380 (47%), Gaps = 42/380 (11%)

Query: 4   LDANVSSEEGFGSV--EKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVS 61
           L  N ++  G   V  E  +    L+  +L  + GNLLV+VA+ W  +L+ + TN F+ S
Sbjct: 20  LAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTM-TNVFVTS 78

Query: 62  LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121
           LA ADL++ +LV+P  A   +   W  G   C + TS+DVL  TASI  LC +++DRY A
Sbjct: 79  LAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLA 138

Query: 122 ICCQPLVYRNKMTP--LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNS 179
           +   PL Y   +T    R A++L   WV+   +SF PIM  W  +G     +      +S
Sbjct: 139 V-TNPLRYGALVTKRCARTAVVL--VWVVSAAVSFAPIMSQWWRVG----ADAEAQRCHS 191

Query: 180 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 239
           N   C F  N PY +  S V+FY+P L+M+  Y R++V A      ++         ES 
Sbjct: 192 NPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESP 251

Query: 240 PQSADQHSTHRMRT---------------------ETKAAKTLCIIMGCFCLCWAPFFVT 278
           P  +   +   + T                     E +A  TL +IMG F LCW PFF+ 
Sbjct: 252 PAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLA 311

Query: 279 NIVDPFIDYT-VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERY--- 334
           N++      + VPG  + A  WLGY NS  NP +Y   +  FR AF  +LC    R    
Sbjct: 312 NVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYC-RSPDFRSAFRRLLCRCGRRLPPE 370

Query: 335 ----RRPSILGQTVPCSTTT 350
                RP++    VP + ++
Sbjct: 371 PCAAARPALFPSGVPAARSS 390


>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
          Length = 342

 Score =  170 bits (430), Expect = 3e-42
 Identities = 101/320 (31%), Positives = 161/320 (50%), Gaps = 14/320 (4%)

Query: 11  EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70
           E  +    +V+L T  S   L+A+ GNLLVM +V   +QL    TN+ I SLA AD LV 
Sbjct: 23  ETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHS-PTNFLIASLACADFLVG 81

Query: 71  VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYR 130
           V VM F  +  V+  W +G  FC + +  DV    +S+ HLC I +DRY  +   PLVY 
Sbjct: 82  VTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVV-TDPLVYA 140

Query: 131 NKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNK 190
            K T     + +   W++P   S      G N+ G+ +L+             C  +V++
Sbjct: 141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGG-----CQIIVSQ 195

Query: 191 PYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR 250
            + +    + F+IP L+M++ Y +I++ AK+ A +I+       +S     S++ +    
Sbjct: 196 GW-VLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIE------TTSSKVESSSESYKIRV 248

Query: 251 MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPF 310
            + E KAAKTL + +  F + W P+ V  ++D F+ +  P  ++    W  Y NS +NP 
Sbjct: 249 AKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPL 308

Query: 311 LYAFLNKSFRRAFLIILCCD 330
           +YA     FR+A  +IL  D
Sbjct: 309 IYALFYPWFRKAIKLILSGD 328


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.140    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,361,995
Number of Sequences: 37866
Number of extensions: 641068
Number of successful extensions: 3756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 324
Number of HSP's successfully gapped in prelim test: 352
Number of HSP's that attempted gapping in prelim test: 2235
Number of HSP's gapped (non-prelim): 1006
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.