Guide to the Human Genome
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Search of human proteins with 92859638

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|92859638 synaptotagmin V [Homo sapiens]
         (386 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|92859638 synaptotagmin V [Homo sapiens]                            786   0.0  
gi|211059429 synaptotagmin II [Homo sapiens]                          481   e-136
gi|31543670 synaptotagmin II [Homo sapiens]                           481   e-136
gi|209447073 synaptotagmin I [Homo sapiens]                           474   e-134
gi|5032139 synaptotagmin I [Homo sapiens]                             474   e-134
gi|209447070 synaptotagmin I [Homo sapiens]                           474   e-134
gi|45504376 synaptotagmin VI [Homo sapiens]                           292   3e-79
gi|94536846 synaptotagmin VIII [Homo sapiens]                         280   2e-75
gi|39752671 synaptotagmin X [Homo sapiens]                            279   3e-75
gi|28376627 synaptotagmin IX [Homo sapiens]                           274   9e-74
gi|238550198 synaptotagmin III [Homo sapiens]                         271   9e-73
gi|238550196 synaptotagmin III [Homo sapiens]                         271   9e-73
gi|14150054 synaptotagmin III [Homo sapiens]                          271   9e-73
gi|38570146 synaptotagmin VII [Homo sapiens]                          268   8e-72
gi|216548478 synaptotagmin XI [Homo sapiens]                          233   3e-61
gi|24308219 synaptotagmin IV [Homo sapiens]                           225   6e-59
gi|40068038 B/K protein [Homo sapiens]                                209   3e-54
gi|29366828 synaptotagmin XII [Homo sapiens]                          172   4e-43
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 172   4e-43
gi|6005997 double C2-like domains, beta [Homo sapiens]                172   6e-43
gi|47078261 double C2-like domains, alpha [Homo sapiens]              164   1e-40
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            155   8e-38
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             155   8e-38
gi|24308233 synaptotagmin XIII [Homo sapiens]                         145   8e-35
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 143   2e-34
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      143   3e-34
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      143   3e-34
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]            129   6e-30
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]            129   6e-30
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]             129   6e-30

>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  786 bits (2031), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG 60
           MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
Sbjct: 1   MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG 60

Query: 61  KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF 120
           KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
Sbjct: 61  KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF 120

Query: 121 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK 180
           QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
Sbjct: 121 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK 180

Query: 181 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL 240
           VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
Sbjct: 181 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL 240

Query: 241 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN 300
           GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
Sbjct: 241 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN 300

Query: 301 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM 360
           TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
Sbjct: 301 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM 360

Query: 361 LANPRRPIAQWHSLRPPDRVRLLPAP 386
           LANPRRPIAQWHSLRPPDRVRLLPAP
Sbjct: 361 LANPRRPIAQWHSLRPPDRVRLLPAP 386


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  481 bits (1237), Expect = e-136
 Identities = 228/366 (62%), Positives = 293/366 (80%), Gaps = 6/366 (1%)

Query: 20  SRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC-RRRTGKKSQAQAQVHLQEVKGL- 77
           + I+  P+PPWAL  I +V+GLL+ +CCFC+ +K C +++  KK + +   +   +K + 
Sbjct: 53  NEINKIPLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMK 112

Query: 78  GQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAA 137
           G    D  +  + E E    G G++  +   LG+LQ+SLDYDFQ+ QL VG+LQA  L A
Sbjct: 113 GGQDDDDAETGLTEGE----GEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA 168

Query: 138 LDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYD 197
           LD+GG+SDPYV+V+LLPDK+++YETKVHR+TLNP F ETF FKVPY ELGG+ LVMA+YD
Sbjct: 169 LDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYD 228

Query: 198 FDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLT 257
           FDRFS++D IGEV+VPM++VDLG+P++ WR+LQ   +EE EKLGDIC SLRYVPTAGKLT
Sbjct: 229 FDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLT 288

Query: 258 VIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCD 317
           V +LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KKKTT+KK TLNPY+NE+FSFE+P +
Sbjct: 289 VCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFE 348

Query: 318 QVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPP 377
           Q+QKVQV +TVLDYDKLGKNEAIG++ VG+ A G  LRHW+DMLANPRRPIAQWHSL+P 
Sbjct: 349 QIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPE 408

Query: 378 DRVRLL 383
           + V  L
Sbjct: 409 EEVDAL 414


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  481 bits (1237), Expect = e-136
 Identities = 228/366 (62%), Positives = 293/366 (80%), Gaps = 6/366 (1%)

Query: 20  SRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC-RRRTGKKSQAQAQVHLQEVKGL- 77
           + I+  P+PPWAL  I +V+GLL+ +CCFC+ +K C +++  KK + +   +   +K + 
Sbjct: 53  NEINKIPLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMK 112

Query: 78  GQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAA 137
           G    D  +  + E E    G G++  +   LG+LQ+SLDYDFQ+ QL VG+LQA  L A
Sbjct: 113 GGQDDDDAETGLTEGE----GEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA 168

Query: 138 LDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYD 197
           LD+GG+SDPYV+V+LLPDK+++YETKVHR+TLNP F ETF FKVPY ELGG+ LVMA+YD
Sbjct: 169 LDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYD 228

Query: 198 FDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLT 257
           FDRFS++D IGEV+VPM++VDLG+P++ WR+LQ   +EE EKLGDIC SLRYVPTAGKLT
Sbjct: 229 FDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLT 288

Query: 258 VIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCD 317
           V +LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KKKTT+KK TLNPY+NE+FSFE+P +
Sbjct: 289 VCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFE 348

Query: 318 QVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPP 377
           Q+QKVQV +TVLDYDKLGKNEAIG++ VG+ A G  LRHW+DMLANPRRPIAQWHSL+P 
Sbjct: 349 QIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPE 408

Query: 378 DRVRLL 383
           + V  L
Sbjct: 409 EEVDAL 414


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  474 bits (1221), Expect = e-134
 Identities = 231/387 (59%), Positives = 299/387 (77%), Gaps = 10/387 (2%)

Query: 4   EPPTPGPPSPDT-----PPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC--- 55
           EP +PG    D          + +   P+PPWAL  I +V+ LL+ +CCFC+ +K     
Sbjct: 28  EPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKK 87

Query: 56  -RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE-LGRLQ 113
             ++ GK+   +  +++++VK LG++  D+   + +       G  ++   + E LG+LQ
Sbjct: 88  KNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQ 147

Query: 114 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF 173
           YSLDYDFQ+ QLLVGI+QA  L ALD+GG+SDPYV+V+LLPDK++++ETKVHR+TLNP F
Sbjct: 148 YSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVF 207

Query: 174 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP 233
            E F FKVPY ELGG+ LVMAVYDFDRFS++D IGE +VPM++VD G   + WR+LQ+A 
Sbjct: 208 NEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAE 267

Query: 234 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK 293
           +EEQEKLGDICFSLRYVPTAGKLTV++LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KK
Sbjct: 268 KEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKK 327

Query: 294 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG 353
           KTTIKKNTLNPYYNE+FSFEVP +Q+QKVQV +TVLDYDK+GKN+AIG+V VG  + GA 
Sbjct: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAE 387

Query: 354 LRHWADMLANPRRPIAQWHSLRPPDRV 380
           LRHW+DMLANPRRPIAQWH+L+  + V
Sbjct: 388 LRHWSDMLANPRRPIAQWHTLQVEEEV 414


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  474 bits (1221), Expect = e-134
 Identities = 231/387 (59%), Positives = 299/387 (77%), Gaps = 10/387 (2%)

Query: 4   EPPTPGPPSPDT-----PPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC--- 55
           EP +PG    D          + +   P+PPWAL  I +V+ LL+ +CCFC+ +K     
Sbjct: 28  EPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKK 87

Query: 56  -RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE-LGRLQ 113
             ++ GK+   +  +++++VK LG++  D+   + +       G  ++   + E LG+LQ
Sbjct: 88  KNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQ 147

Query: 114 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF 173
           YSLDYDFQ+ QLLVGI+QA  L ALD+GG+SDPYV+V+LLPDK++++ETKVHR+TLNP F
Sbjct: 148 YSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVF 207

Query: 174 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP 233
            E F FKVPY ELGG+ LVMAVYDFDRFS++D IGE +VPM++VD G   + WR+LQ+A 
Sbjct: 208 NEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAE 267

Query: 234 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK 293
           +EEQEKLGDICFSLRYVPTAGKLTV++LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KK
Sbjct: 268 KEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKK 327

Query: 294 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG 353
           KTTIKKNTLNPYYNE+FSFEVP +Q+QKVQV +TVLDYDK+GKN+AIG+V VG  + GA 
Sbjct: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAE 387

Query: 354 LRHWADMLANPRRPIAQWHSLRPPDRV 380
           LRHW+DMLANPRRPIAQWH+L+  + V
Sbjct: 388 LRHWSDMLANPRRPIAQWHTLQVEEEV 414


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  474 bits (1221), Expect = e-134
 Identities = 231/387 (59%), Positives = 299/387 (77%), Gaps = 10/387 (2%)

Query: 4   EPPTPGPPSPDT-----PPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC--- 55
           EP +PG    D          + +   P+PPWAL  I +V+ LL+ +CCFC+ +K     
Sbjct: 28  EPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKK 87

Query: 56  -RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE-LGRLQ 113
             ++ GK+   +  +++++VK LG++  D+   + +       G  ++   + E LG+LQ
Sbjct: 88  KNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQ 147

Query: 114 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF 173
           YSLDYDFQ+ QLLVGI+QA  L ALD+GG+SDPYV+V+LLPDK++++ETKVHR+TLNP F
Sbjct: 148 YSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVF 207

Query: 174 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP 233
            E F FKVPY ELGG+ LVMAVYDFDRFS++D IGE +VPM++VD G   + WR+LQ+A 
Sbjct: 208 NEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAE 267

Query: 234 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK 293
           +EEQEKLGDICFSLRYVPTAGKLTV++LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KK
Sbjct: 268 KEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKK 327

Query: 294 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG 353
           KTTIKKNTLNPYYNE+FSFEVP +Q+QKVQV +TVLDYDK+GKN+AIG+V VG  + GA 
Sbjct: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAE 387

Query: 354 LRHWADMLANPRRPIAQWHSLRPPDRV 380
           LRHW+DMLANPRRPIAQWH+L+  + V
Sbjct: 388 LRHWSDMLANPRRPIAQWHTLQVEEEV 414


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  292 bits (748), Expect = 3e-79
 Identities = 154/331 (46%), Positives = 216/331 (65%), Gaps = 12/331 (3%)

Query: 54  SCRRRTGKKSQAQAQVHLQEVKGLGQ--------SYIDKVQPEVEELEPAPSGPGQQVAD 105
           S  R T  K     Q+H+  V    +        + I +++PE+ + +       +  A 
Sbjct: 83  SSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEAT 142

Query: 106 KHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVH 165
           K   G++ +SL YD+++  L+V IL+A  L A D  GSSDPYV++YLLPD++ + +T+VH
Sbjct: 143 K-SCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVH 201

Query: 166 RQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVP--MSSVDLGRPV 223
           R+TLNP F E F F VPY EL  R L ++V+DFDRFSR+D IGEV +     + DL R  
Sbjct: 202 RKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRET 261

Query: 224 QAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHL 283
             W+++Q A  E  + LG+I FSL Y+PTAG+LT+ V++ +NLK MD+ G SDPYVKV L
Sbjct: 262 SIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSL 320

Query: 284 LQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV 343
           L  G++++KKKTTIKKNTLNP YNEA  F++P + + +V + ++V+DYD++G NE IG  
Sbjct: 321 LCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVC 380

Query: 344 AVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374
            VG  A G G  HW +MLA PR+PIA WHSL
Sbjct: 381 RVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  280 bits (715), Expect = 2e-75
 Identities = 163/380 (42%), Positives = 227/380 (59%), Gaps = 21/380 (5%)

Query: 3   PEPPTPGPPS--PDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG 60
           P  P P   +  P   PD   ++  P P WAL    L +G+L+ SC  C     CRR   
Sbjct: 22  PSAPAPAGTTAIPGLIPDL--VAGTPWPRWALIAGALAAGVLLVSCLLCAACCCCRRHR- 78

Query: 61  KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF 120
           KK + +  V L   +G   +++  VQP+V+ LE +P        D  + GRLQ SL++DF
Sbjct: 79  KKPRDKESVGLGSARGTTTTHL--VQPDVDGLESSPG-------DAQQWGRLQLSLEFDF 129

Query: 121 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK 180
            S ++ VG+ QA   A L  GG+ DPY RV +      R+ETKVHR TL P F ET  F 
Sbjct: 130 GSQEIRVGLRQA---ADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH 186

Query: 181 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL 240
           +P  EL G  L + +++F RFS ++ +GE+R+P+ +VDL   ++ W  L      + E++
Sbjct: 187 IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQV 246

Query: 241 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN 300
           G++CFSLRYVP++G+LTV+VLEA+ L+     GL++PYVKV L+   +K +K+KT  KK 
Sbjct: 247 GELCFSLRYVPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKG 302

Query: 301 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM 360
           T  PY+NEAF+F VP  QVQ V + L V D     + E +G+V +GA A G  L+HWADM
Sbjct: 303 TAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADM 362

Query: 361 LANPRRPIAQWHSLRPPDRV 380
           LA+ RRPIAQ H LRP   V
Sbjct: 363 LAHARRPIAQRHPLRPAREV 382


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  279 bits (713), Expect = 3e-75
 Identities = 140/302 (46%), Positives = 203/302 (67%), Gaps = 4/302 (1%)

Query: 75  KGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMG 134
           +G   + I +++PE+ + +   S  G Q  D    G+L ++L YD+++  L+V I++A+ 
Sbjct: 199 RGETTTSIGRIKPELYKQKSVDS-EGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALD 257

Query: 135 LAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMA 194
           L A D  G+SDPYV++YLLPD++++++T+VHR+TLNP F ETF F V Y +L  R L  +
Sbjct: 258 LPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFS 317

Query: 195 VYDFDRFSRNDAIGEVRVP--MSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPT 252
           VYDFDRFSR+D IGEV +       DL R    W+++  A  E  + LG+I FSL Y+PT
Sbjct: 318 VYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPT 376

Query: 253 AGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSF 312
           AG++T+ V++ +NLK MD+ G SDPYVKV L+  G++++K+KTT KKNTLNP YNEA  F
Sbjct: 377 AGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIF 436

Query: 313 EVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWH 372
           ++P + V +V + + V+DYD++G NE IG    G  A G G  HW +MLA  R+PI  WH
Sbjct: 437 DIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWH 496

Query: 373 SL 374
            L
Sbjct: 497 PL 498


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  274 bits (701), Expect = 9e-74
 Identities = 135/295 (45%), Positives = 200/295 (67%), Gaps = 4/295 (1%)

Query: 82  IDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLG 141
           I +++PE+ +     +  G++   K   G+L + L YD    QL+V I +A+ L A D  
Sbjct: 195 IGRIKPELYKQRSLDNDDGRRSNSK-ACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFS 253

Query: 142 GSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRF 201
           G+SDPYV++YLLPD++ +++TKVHR+TLNP F E F F VPY +L  R L  +VYDFDRF
Sbjct: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313

Query: 202 SRNDAIGEVRVP--MSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVI 259
           SR+D IG+V V   +   D  R    W++++    +  + LG++ FSL Y+PTAG+LT+ 
Sbjct: 314 SRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVD-LGELMFSLCYLPTAGRLTIT 372

Query: 260 VLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQV 319
           +++A+NLK MD+ G SDPYVKV L+  G++++K+KT+ K+NTLNP YNEA  F+VP + +
Sbjct: 373 IIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENI 432

Query: 320 QKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374
            ++ + + V+DYD++G NE IG   VG  A   G  HW++ML+ PR+PIA WHSL
Sbjct: 433 DQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSL 487


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  271 bits (692), Expect = 9e-73
 Identities = 141/283 (49%), Positives = 193/283 (68%), Gaps = 9/283 (3%)

Query: 98  GPGQ-QVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDK 156
           GPG  +       GR+ ++L Y + S QL+V ILQA+ L A D  G SDPYV++YLLPD+
Sbjct: 288 GPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR 347

Query: 157 RRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEV----RV 212
           +++++TKVHR+TLNP F ETF F VP  EL  R L  +VYDFDRFSR+D IG+V     +
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 213 PMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVG 272
            ++     RP+  WR++     E+ + LG++ FSL Y+PTAG+LTV +++A NLK MD+ 
Sbjct: 408 ELAEQPPDRPL--WRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464

Query: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332
           G SDPYVK  L+  G++++K+KT+IKKNTLNP YNEA  F+V  + V+ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524

Query: 333 KLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSL 374
            +G NE IG   VG  AA   G  HWA+MLANPR+P+  WH L
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  271 bits (692), Expect = 9e-73
 Identities = 141/283 (49%), Positives = 193/283 (68%), Gaps = 9/283 (3%)

Query: 98  GPGQ-QVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDK 156
           GPG  +       GR+ ++L Y + S QL+V ILQA+ L A D  G SDPYV++YLLPD+
Sbjct: 288 GPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR 347

Query: 157 RRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEV----RV 212
           +++++TKVHR+TLNP F ETF F VP  EL  R L  +VYDFDRFSR+D IG+V     +
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 213 PMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVG 272
            ++     RP+  WR++     E+ + LG++ FSL Y+PTAG+LTV +++A NLK MD+ 
Sbjct: 408 ELAEQPPDRPL--WRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464

Query: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332
           G SDPYVK  L+  G++++K+KT+IKKNTLNP YNEA  F+V  + V+ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524

Query: 333 KLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSL 374
            +G NE IG   VG  AA   G  HWA+MLANPR+P+  WH L
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  271 bits (692), Expect = 9e-73
 Identities = 141/283 (49%), Positives = 193/283 (68%), Gaps = 9/283 (3%)

Query: 98  GPGQ-QVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDK 156
           GPG  +       GR+ ++L Y + S QL+V ILQA+ L A D  G SDPYV++YLLPD+
Sbjct: 288 GPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR 347

Query: 157 RRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEV----RV 212
           +++++TKVHR+TLNP F ETF F VP  EL  R L  +VYDFDRFSR+D IG+V     +
Sbjct: 348 KKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 213 PMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVG 272
            ++     RP+  WR++     E+ + LG++ FSL Y+PTAG+LTV +++A NLK MD+ 
Sbjct: 408 ELAEQPPDRPL--WRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464

Query: 273 GLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332
           G SDPYVK  L+  G++++K+KT+IKKNTLNP YNEA  F+V  + V+ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524

Query: 333 KLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSL 374
            +G NE IG   VG  AA   G  HWA+MLANPR+P+  WH L
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQL 567


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  268 bits (684), Expect = 8e-72
 Identities = 127/284 (44%), Positives = 193/284 (67%), Gaps = 8/284 (2%)

Query: 99  PGQQVADKHE------LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYL 152
           PG +  + HE      LGR+Q+S+ Y+FQ   L V I++A  L A D  G+SDP+V++YL
Sbjct: 120 PGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYL 179

Query: 153 LPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVR 211
           LPDK+ + ETKV R+ LNPH+ ETF F+  PY ++  R+L + V D+DRFSRND IGEV 
Sbjct: 180 LPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVS 239

Query: 212 VPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDV 271
           +P++ VDL +    W++L+        + G++  SL Y P+A  + V +++A+NLK MD+
Sbjct: 240 IPLNKVDLTQMQTFWKDLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDI 298

Query: 272 GGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDY 331
           GG SDPYVKV L+   K+V KKKT   K  LNP +NE+F+F++P +++++  + +TV+D 
Sbjct: 299 GGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDK 358

Query: 332 DKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLR 375
           DKL +N+ IG++ +   +G   ++HW DM+A PR+P+AQWH L+
Sbjct: 359 DKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 402


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  233 bits (593), Expect = 3e-61
 Identities = 126/290 (43%), Positives = 188/290 (64%), Gaps = 9/290 (3%)

Query: 90  EELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALD-LGGSSDPYV 148
           E    +PS P + V     LG L +S+DY+F    L+V I +A GL  +D     SDPY+
Sbjct: 143 ESKTTSPSSPEEDVM----LGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYI 198

Query: 149 RVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAI 207
           ++ +LPDKR R +T+V R+TL+P F ETF F  +PY +L   VL   V  FDRFSR+D I
Sbjct: 199 KMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVI 258

Query: 208 GEVRVPMSSVDLGR-PVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNL 266
           GEV VP++ VD     VQ  R++     ++    G++  SL Y P A ++TV+VL+A++L
Sbjct: 259 GEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHL 318

Query: 267 KKMDVGGLS-DPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVE 325
            KMD+ GLS +PYVKV++  G K++ KKKT +KK TLNP +NE+F +++P D +  + +E
Sbjct: 319 PKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIE 378

Query: 326 LTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSL 374
             V+D+D+  KNE +GR+ +GA +   +G  HW ++  +PR+P+A+WHSL
Sbjct: 379 FLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  225 bits (573), Expect = 6e-59
 Identities = 121/295 (41%), Positives = 183/295 (62%), Gaps = 5/295 (1%)

Query: 83  DKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGG 142
           +K     E L+ + S   ++  +K  LG L +SL+Y+F+    +V I +A GL A+D   
Sbjct: 130 EKESVSPESLKSSTSLTSEEKQEK--LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187

Query: 143 -SSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDR 200
            +SDPY+++ +LP+K+ + +T+V R+TL+P F ETF F  +PY ++    L   +  FDR
Sbjct: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247

Query: 201 FSRNDAIGEVRVPMSSVDLGRPVQAW-RELQAAPREEQEKLGDICFSLRYVPTAGKLTVI 259
           FSR+D IGEV +P+S ++L        RE+      +    G++  SL Y  T   LTV+
Sbjct: 248 FSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVV 307

Query: 260 VLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQV 319
           VL+A++L K DV GLSDPYVKV+L    K++ KKKT +KK T N  +NE F F++PC+ +
Sbjct: 308 VLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGL 367

Query: 320 QKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374
           + + VE  VLD ++  +NE IG++ +GAAA G G  HW ++   PRR IA+WH L
Sbjct: 368 EDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  209 bits (532), Expect = 3e-54
 Identities = 114/307 (37%), Positives = 181/307 (58%), Gaps = 13/307 (4%)

Query: 81  YIDKVQPEVEELEP----APSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLA 136
           Y  K +P +  L+       S   +++  K++LG L +S  YD     L V +++A  L 
Sbjct: 153 YFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLP 212

Query: 137 A-LDLGGS------SDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGR 189
             +   GS      S+PYV++ LLPD++   +T V R+T  P F E + F++P++E   R
Sbjct: 213 PPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRR 272

Query: 190 VLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRY 249
            L++ V DFD+FSR+  IG+V VP+  VDL +    W+ L  + + E E LG++  SL Y
Sbjct: 273 TLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNY 331

Query: 250 VPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEA 309
           +P+AG+L V V+ AK L + DV   SDP+VK+ L+ G K V+ KKT+  + T++P+YNE+
Sbjct: 332 LPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNES 391

Query: 310 FSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPI 368
           FSF+VP ++++   +  TV  ++    N+ IGR+ +G  ++G +   HW  ML   R  +
Sbjct: 392 FSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAV 451

Query: 369 AQWHSLR 375
            QWHSLR
Sbjct: 452 EQWHSLR 458


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  172 bits (437), Expect = 4e-43
 Identities = 95/268 (35%), Positives = 154/268 (57%), Gaps = 2/268 (0%)

Query: 109 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT 168
           LG+++ S++YD  S  L V ++Q   L   +       ++RV LLPD++    +++ R  
Sbjct: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212

Query: 169 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLG-RPVQAWR 227
            +  F E F+  +    L  + L  +V+  D   RN + G V + +S +DL  +P   W 
Sbjct: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272

Query: 228 ELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGG 287
            LQ    +  + +G+I  SL Y+PTA +LTV+V++AKNL   +    +DP+VKV+LLQ G
Sbjct: 273 YLQDQ-NKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331

Query: 288 KKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA 347
           +K+ KKKT +K++  NP +NEA  F VP   +Q + + +TV +    G+ + +G V +G 
Sbjct: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391

Query: 348 AAGGAGLRHWADMLANPRRPIAQWHSLR 375
           +A G G  HW  MLA  RRP++ WH++R
Sbjct: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  172 bits (437), Expect = 4e-43
 Identities = 98/270 (36%), Positives = 155/270 (57%), Gaps = 6/270 (2%)

Query: 109 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT 168
           LGRL +S++Y+ ++ +LLVG+++A  L A     +  P V++YLLPD+RR  ++K  R+T
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPS--ETCSPLVKLYLLPDERRFLQSKTKRKT 205

Query: 169 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQA--W 226
            NP F E F F+V    +  RVL  +VY  DR  ++  +G+V  P+ +  L    +   W
Sbjct: 206 SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIW 265

Query: 227 RELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG 286
           R+L+A   E   + GD+ F L Y     +LTV+VL AK L+  +  G+   +VKV L+  
Sbjct: 266 RDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325

Query: 287 GKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVG 346
            K V+ KKT+    ++NP YNE FSF+    ++    + LTV+   +  K++ +GRV VG
Sbjct: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVG 385

Query: 347 --AAAGGAGLRHWADMLANPRRPIAQWHSL 374
                 G  L HW +ML+ P+  + +WH+L
Sbjct: 386 PYMYTRGRELEHWDEMLSKPKELVKRWHAL 415



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 45/159 (28%), Positives = 73/159 (45%), Gaps = 13/159 (8%)

Query: 88  EVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPY 147
           E E LEP PS          E G LQ+ L Y+    +L V +L+A GL   +  G    +
Sbjct: 269 EAESLEP-PS----------EFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVF 317

Query: 148 VRVYLLPDKR--RRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRND 205
           V+V L+   +  +  +T     ++NP + ETF+FK    EL    L + V       ++ 
Sbjct: 318 VKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQ 377

Query: 206 AIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDIC 244
            +G V V       GR ++ W E+ + P+E  ++   +C
Sbjct: 378 QLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALC 416


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  172 bits (435), Expect = 6e-43
 Identities = 107/298 (35%), Positives = 156/298 (52%), Gaps = 9/298 (3%)

Query: 86  QPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSD 145
           +P  +  E  P   G +  D   LG L +SL YD ++  L   I +A GL  +D  G +D
Sbjct: 104 RPPAKPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLAD 163

Query: 146 PYVRVYLLP--DKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFS 202
           PYV+++LLP   K  +  TK  R TLNP + ET  +  +   ++  + L ++V D D+F 
Sbjct: 164 PYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFR 223

Query: 203 RNDAIGEVRVPMSSVDLGRP----VQAWRELQAAPREEQ--EKLGDICFSLRYVPTAGKL 256
            N+ IGE RVP+  +         +   ++L     E++  E+ G I  SL+Y      L
Sbjct: 224 HNEFIGETRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGL 283

Query: 257 TVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPC 316
            V ++   +L  MD  G SDPYVK +L     K  K KT +KK TLNP +NE F +E+  
Sbjct: 284 LVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKH 343

Query: 317 DQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374
             + K  +E+TV DYD    N+ IG V +G  A G  L+HW D L N  + I +WH+L
Sbjct: 344 GDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTL 401


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  164 bits (416), Expect = 1e-40
 Identities = 108/301 (35%), Positives = 152/301 (50%), Gaps = 31/301 (10%)

Query: 105 DKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPD--KRRRYET 162
           D   LG L++ L YD  S  L   IL+A GL  +D  G +DPYV+++LLP   K  + +T
Sbjct: 86  DATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKT 145

Query: 163 KVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMS------ 215
           K  R TLNP + E   +  +   ++  +VL +AV D D+ S N+ IGE+RVP+       
Sbjct: 146 KTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQ 205

Query: 216 ----------SVDLGRPVQA----------WRELQAAPREEQ--EKLGDICFSLRYVPTA 253
                      V L  P              +EL+ A + +   E+ G I  SL Y    
Sbjct: 206 KKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRR 265

Query: 254 GKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE 313
             L V +L   +L  MDV G SDPYVK +L     K  K KT +KK TLNP +NE F +E
Sbjct: 266 RGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYE 325

Query: 314 VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHS 373
           +    +    +E+TV DYD    N+ IG V++G  A G   +HW+D L  P   + +WH+
Sbjct: 326 IELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHT 385

Query: 374 L 374
           L
Sbjct: 386 L 386



 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 47/119 (39%), Positives = 66/119 (55%), Gaps = 1/119 (0%)

Query: 228 ELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGG 287
           E+ +   ++   LG + F L Y   +  L   +L AK LK MD  GL+DPYVK+HLL G 
Sbjct: 78  EVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGA 137

Query: 288 KKVRKKKTTIKKNTLNPYYNEAFSFE-VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAV 345
            K  K KT  ++NTLNP +NE  ++  +  D +    + + V D DKL  NE IG + V
Sbjct: 138 CKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRV 196


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  155 bits (391), Expect = 8e-38
 Identities = 105/321 (32%), Positives = 156/321 (48%), Gaps = 30/321 (9%)

Query: 87  PEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDP 146
           P  EE E A S    +      LG L++SL YD  +  L   I++A GL  +D  G +DP
Sbjct: 374 PPEEEEEEANSYDSDEATT---LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADP 430

Query: 147 YVRVYLLP--DKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSR 203
           YV+++LLP   K  +  TK  R T NP + ET  +  +   ++  + L ++V D D+F  
Sbjct: 431 YVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGH 490

Query: 204 NDAIGEVR---------------------VPMS---SVDLGRPVQAWRELQAAPREEQEK 239
           N+ IGE R                     +PM    +    R +  + E Q     + E+
Sbjct: 491 NEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEE 550

Query: 240 LGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKK 299
            G I  SL Y    G L V ++   +L  MD  G SDP+VK+ L     K  K KT IKK
Sbjct: 551 RGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKK 610

Query: 300 NTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWAD 359
            TLNP +NE F +++    + K  ++++V DYD    N+ IG   +G +A G  L+HW +
Sbjct: 611 KTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYE 670

Query: 360 MLANPRRPIAQWHSLRPPDRV 380
            L N  + I +WH L+  + V
Sbjct: 671 CLKNKDKKIERWHQLQNENHV 691


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  155 bits (391), Expect = 8e-38
 Identities = 105/321 (32%), Positives = 156/321 (48%), Gaps = 30/321 (9%)

Query: 87  PEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDP 146
           P  EE E A S    +      LG L++SL YD  +  L   I++A GL  +D  G +DP
Sbjct: 370 PPEEEEEEANSYDSDEATT---LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADP 426

Query: 147 YVRVYLLP--DKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSR 203
           YV+++LLP   K  +  TK  R T NP + ET  +  +   ++  + L ++V D D+F  
Sbjct: 427 YVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGH 486

Query: 204 NDAIGEVR---------------------VPMS---SVDLGRPVQAWRELQAAPREEQEK 239
           N+ IGE R                     +PM    +    R +  + E Q     + E+
Sbjct: 487 NEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEE 546

Query: 240 LGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKK 299
            G I  SL Y    G L V ++   +L  MD  G SDP+VK+ L     K  K KT IKK
Sbjct: 547 RGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKK 606

Query: 300 NTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWAD 359
            TLNP +NE F +++    + K  ++++V DYD    N+ IG   +G +A G  L+HW +
Sbjct: 607 KTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYE 666

Query: 360 MLANPRRPIAQWHSLRPPDRV 380
            L N  + I +WH L+  + V
Sbjct: 667 CLKNKDKKIERWHQLQNENHV 687


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  145 bits (365), Expect = 8e-35
 Identities = 89/277 (32%), Positives = 142/277 (51%), Gaps = 6/277 (2%)

Query: 101 QQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRR-R 159
           ++ A  ++  +L Y LDYD Q  +L V  L+A+     +  G  D YV+  +        
Sbjct: 151 EKAASWNQAPKLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVE 207

Query: 160 YETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDL 219
            +T + ++ L+  + E     +   EL    L + +   DRFSR+   GE+R+ +    +
Sbjct: 208 AQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSV 267

Query: 220 GRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGL--SDP 277
                 W EL+ + +E     G++  S+ Y+P A +L V++++AKNL       L   D 
Sbjct: 268 PLGAAQWGELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDV 327

Query: 278 YVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKN 337
            VKV L    +K++KK+T   K+ +NP +NE   FE+P D +Q   VEL VL  D  G++
Sbjct: 328 SVKVTLKHQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQS 387

Query: 338 EAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374
            A+G  ++G    G+   HW +ML NPRR IA WH L
Sbjct: 388 CALGHCSLGLHTSGSERSHWEEMLKNPRRQIAMWHQL 424


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  143 bits (361), Expect = 2e-34
 Identities = 82/223 (36%), Positives = 129/223 (57%), Gaps = 4/223 (1%)

Query: 109 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT 168
           LGRL +S++Y+ ++ +LLVG+++A  L A     +  P V++YLLPD+RR  ++K  R+T
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPS--ETCSPLVKLYLLPDERRFLQSKTKRKT 205

Query: 169 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQA--W 226
            NP F E F F+V    +  RVL  +VY  DR  ++  +G+V  P+ +  L    +   W
Sbjct: 206 SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIW 265

Query: 227 RELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG 286
           R+L+A   E   + GD+ F L Y     +LTV+VL AK L+  +  G+   +VKV L+  
Sbjct: 266 RDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325

Query: 287 GKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVL 329
            K V+ KKT+    ++NP YNE FSF+    ++    + LTV+
Sbjct: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 14/158 (8%)

Query: 228 ELQAAPREEQEK------LGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKV 281
           EL   P ++ E       LG + FS+ Y   A +L V +++A++L+         P VK+
Sbjct: 130 ELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSE--TCSPLVKL 187

Query: 282 HLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIG 341
           +LL   ++  + KT  K+ T NP ++E F F+V    + +  ++ +V   D+  K++ +G
Sbjct: 188 YLLPDERRFLQSKT--KRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245

Query: 342 RVAV----GAAAGGAGLRHWADMLANPRRPIAQWHSLR 375
           +V          G      W D+ A    P +++  L+
Sbjct: 246 QVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQ 283



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 13/110 (11%)

Query: 88  EVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPY 147
           E E LEP PS          E G LQ+ L Y+    +L V +L+A GL   +  G    +
Sbjct: 269 EAESLEP-PS----------EFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVF 317

Query: 148 VRVYLLPDKR--RRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAV 195
           V+V L+   +  +  +T     ++NP + ETF+FK    EL    L + V
Sbjct: 318 VKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTV 367


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  143 bits (360), Expect = 3e-34
 Identities = 94/291 (32%), Positives = 145/291 (49%), Gaps = 26/291 (8%)

Query: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRR--RYETKVHR 166
           GR+ +SL Y+ Q+  L+V + +   LA  D     S+PYV+ YLLPDK R  + +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 167 QTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAW 226
            T+NP + ET  +++P   L  R L  +V+   RF RN  +GE  + M S  L + +   
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 227 RELQA-----APREEQEKLGDICFSLRYVPTA----------------GKLTVIVLEAKN 265
             L       +P       G++  SL+Y+P +                G+L V + EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 266 LKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE-VPCDQVQKVQV 324
           L     GG SD +VK +LL    K  K+KT + K TLNP+YN  F +  V  + +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 325 ELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLR 375
           ELTV D + L  N+ +G V +G   G +      D + +    ++ W  +R
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISN-GEVVDWMDSTGEEVSLWQKMR 647


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  143 bits (360), Expect = 3e-34
 Identities = 94/291 (32%), Positives = 145/291 (49%), Gaps = 26/291 (8%)

Query: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRR--RYETKVHR 166
           GR+ +SL Y+ Q+  L+V + +   LA  D     S+PYV+ YLLPDK R  + +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 167 QTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAW 226
            T+NP + ET  +++P   L  R L  +V+   RF RN  +GE  + M S  L + +   
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 227 RELQA-----APREEQEKLGDICFSLRYVPTA----------------GKLTVIVLEAKN 265
             L       +P       G++  SL+Y+P +                G+L V + EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 266 LKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE-VPCDQVQKVQV 324
           L     GG SD +VK +LL    K  K+KT + K TLNP+YN  F +  V  + +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 325 ELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLR 375
           ELTV D + L  N+ +G V +G   G +      D + +    ++ W  +R
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISN-GEVVDWMDSTGEEVSLWQKMR 647


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  129 bits (323), Expect = 6e-30
 Identities = 91/307 (29%), Positives = 136/307 (44%), Gaps = 49/307 (15%)

Query: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRRRYETKVHRQT 168
           G +   + Y +++G L + +     LA  D     +D YV+ YLLPDK R  + K   +T
Sbjct: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467

Query: 169 -LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWR 227
             NP F ET  + + + +L  R L ++V+ +DRF RN  +GEV +P  S +   P   W 
Sbjct: 468 GTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWF 527

Query: 228 ELQA----APREEQEKLGDICFSLRYVP-----------------------------TAG 254
            LQ     AP    +  G++   LRY+P                             + G
Sbjct: 528 VLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGG 587

Query: 255 KLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE- 313
            L V + EAKNL  +  GG SD +VK +LL    K  K KT + K ++NP +N  F F  
Sbjct: 588 ILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSG 647

Query: 314 VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAG-------------GAGLRHWADM 360
           +    ++ V +ELT+ D +    N  +G V + + +G             G   R W  M
Sbjct: 648 IHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKM 707

Query: 361 LANPRRP 367
             NP  P
Sbjct: 708 ANNPGTP 714


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score =  129 bits (323), Expect = 6e-30
 Identities = 91/307 (29%), Positives = 136/307 (44%), Gaps = 49/307 (15%)

Query: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRRRYETKVHRQT 168
           G +   + Y +++G L + +     LA  D     +D YV+ YLLPDK R  + K   +T
Sbjct: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489

Query: 169 -LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWR 227
             NP F ET  + + + +L  R L ++V+ +DRF RN  +GEV +P  S +   P   W 
Sbjct: 490 GTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWF 549

Query: 228 ELQA----APREEQEKLGDICFSLRYVP-----------------------------TAG 254
            LQ     AP    +  G++   LRY+P                             + G
Sbjct: 550 VLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGG 609

Query: 255 KLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE- 313
            L V + EAKNL  +  GG SD +VK +LL    K  K KT + K ++NP +N  F F  
Sbjct: 610 ILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSG 669

Query: 314 VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAG-------------GAGLRHWADM 360
           +    ++ V +ELT+ D +    N  +G V + + +G             G   R W  M
Sbjct: 670 IHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKM 729

Query: 361 LANPRRP 367
             NP  P
Sbjct: 730 ANNPGTP 736


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  129 bits (323), Expect = 6e-30
 Identities = 91/307 (29%), Positives = 136/307 (44%), Gaps = 49/307 (15%)

Query: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRRRYETKVHRQT 168
           G +   + Y +++G L + +     LA  D     +D YV+ YLLPDK R  + K   +T
Sbjct: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467

Query: 169 -LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWR 227
             NP F ET  + + + +L  R L ++V+ +DRF RN  +GEV +P  S +   P   W 
Sbjct: 468 GTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWF 527

Query: 228 ELQA----APREEQEKLGDICFSLRYVP-----------------------------TAG 254
            LQ     AP    +  G++   LRY+P                             + G
Sbjct: 528 VLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGG 587

Query: 255 KLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE- 313
            L V + EAKNL  +  GG SD +VK +LL    K  K KT + K ++NP +N  F F  
Sbjct: 588 ILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSG 647

Query: 314 VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAG-------------GAGLRHWADM 360
           +    ++ V +ELT+ D +    N  +G V + + +G             G   R W  M
Sbjct: 648 IHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKM 707

Query: 361 LANPRRP 367
             NP  P
Sbjct: 708 ANNPGTP 714


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,014,421
Number of Sequences: 37866
Number of extensions: 828308
Number of successful extensions: 9170
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 7708
Number of HSP's gapped (non-prelim): 1061
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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