Guide to the Human Genome
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Search of human proteins with 14150141

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14150141 programmed cell death 2-like [Homo sapiens]
         (358 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14150141 programmed cell death 2-like [Homo sapiens]               752   0.0  
gi|21735592 programmed cell death 2 isoform 1 [Homo sapiens]          100   2e-21
gi|21735594 programmed cell death 2 isoform 2 [Homo sapiens]           55   1e-07
gi|150378478 PR domain containing 8 [Homo sapiens]                     35   0.14 
gi|150378439 PR domain containing 8 [Homo sapiens]                     35   0.14 
gi|32483412 connexin 40 [Homo sapiens]                                 30   2.6  
gi|6631083 connexin 40 [Homo sapiens]                                  30   2.6  
gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]       30   3.3  
gi|66912172 hairy and enhancer of split 3 [Homo sapiens]               30   4.4  
gi|89040432 PREDICTED: hypothetical protein [Homo sapiens]             28   9.7  
gi|239742637 PREDICTED: hypothetical protein XP_002342585 [Homo ...    28   9.7  
gi|4502175 apical protein of Xenopus-like [Homo sapiens]               28   9.7  

>gi|14150141 programmed cell death 2-like [Homo sapiens]
          Length = 358

 Score =  752 bits (1941), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRPVCQRCGQPLALVV 60
           MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRPVCQRCGQPLALVV
Sbjct: 1   MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRPVCQRCGQPLALVV 60

Query: 61  QVYCPLEGSPFHRLLHVFACACPGCSTGGARSWKVFRSQCLQVPEREAQDAQKQGNSLAA 120
           QVYCPLEGSPFHRLLHVFACACPGCSTGGARSWKVFRSQCLQVPEREAQDAQKQGNSLAA
Sbjct: 61  QVYCPLEGSPFHRLLHVFACACPGCSTGGARSWKVFRSQCLQVPEREAQDAQKQGNSLAA 120

Query: 121 EDWCEGADDWGSDTEEGPSPQFTLDFGNDASSAKDVDWTARLQDLRLQDAVLGAAHPVPP 180
           EDWCEGADDWGSDTEEGPSPQFTLDFGNDASSAKDVDWTARLQDLRLQDAVLGAAHPVPP
Sbjct: 121 EDWCEGADDWGSDTEEGPSPQFTLDFGNDASSAKDVDWTARLQDLRLQDAVLGAAHPVPP 180

Query: 181 GLPLFLPYYICVADEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEK 240
           GLPLFLPYYICVADEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEK
Sbjct: 181 GLPLFLPYYICVADEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEK 240

Query: 241 TIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSQCGGQRIFEF 300
           TIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSQCGGQRIFEF
Sbjct: 241 TIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSQCGGQRIFEF 300

Query: 301 QLMPALVSMLKSANLGLSVEFGTILVYTCEKSCWPPNHQTPMEEFCIIQEDPDELLFK 358
           QLMPALVSMLKSANLGLSVEFGTILVYTCEKSCWPPNHQTPMEEFCIIQEDPDELLFK
Sbjct: 301 QLMPALVSMLKSANLGLSVEFGTILVYTCEKSCWPPNHQTPMEEFCIIQEDPDELLFK 358


>gi|21735592 programmed cell death 2 isoform 1 [Homo sapiens]
          Length = 344

 Score =  100 bits (249), Expect = 2e-21
 Identities = 93/321 (28%), Positives = 144/321 (44%), Gaps = 42/321 (13%)

Query: 30  SKLGGIPDALPTVAAPRP---VCQRCGQPLALVVQVYCPLEGSP--FHRLLHVFACACPG 84
           SK+GG P  L     P P    C+ CG+PL+ ++QVY PL G P  FHR + +F C    
Sbjct: 29  SKVGGRPAWLGAAGLPGPQALACELCGRPLSFLLQVYAPLPGRPDAFHRCIFLFCCREQP 88

Query: 85  CSTGGARSWKVFRSQCLQVPEREAQDAQKQ------GNSLAAE-----DWCEGADDWGSD 133
           C  G     +VFR+Q  +  +  + +   +      G S+  +       C      G  
Sbjct: 89  CCAG----LRVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPK 144

Query: 134 TEEGPSPQFTLDFGNDASSAKDVDWTARLQDLRLQDAVLGAAHPVPPGLPLFLPYYICVA 193
           T       +       +   + +DW    +    Q   L   H +P    LF  + I + 
Sbjct: 145 TCSRCHKAYYC-----SKEHQTLDWRLGHKQACAQPDHLD--HIIPDHNFLFPEFEIVIE 197

Query: 194 DEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKF 253
            ED+    V          DY +  G +M + L + L  D   K+E       D+ F KF
Sbjct: 198 TEDEIMPEVVEKE------DYSEIIG-SMGEALEEEL--DSMAKHESR----EDKIFQKF 244

Query: 254 MKRIAACQEQILRYSWSGEPLFLTCPT-SEVTELPACSQCGGQRIFEFQLMPALVSMLKS 312
             +IA   EQILRY     P++++     +  ++P C  CG +RI EFQ+MP L++ LK+
Sbjct: 245 KTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCP-CGAKRILEFQVMPQLLNYLKA 303

Query: 313 ANLGLSVEFGTILVYTCEKSC 333
             LG S+++G + V+TC +SC
Sbjct: 304 DRLGKSIDWGILAVFTCAESC 324


>gi|21735594 programmed cell death 2 isoform 2 [Homo sapiens]
          Length = 228

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 41/75 (54%), Gaps = 9/75 (12%)

Query: 30 SKLGGIPDALPTVAAPRP---VCQRCGQPLALVVQVYCPLEGSP--FHRLLHVFACACPG 84
          SK+GG P  L     P P    C+ CG+PL+ ++QVY PL G P  FHR + +F C    
Sbjct: 29 SKVGGRPAWLGAAGLPGPQALACELCGRPLSFLLQVYAPLPGRPDAFHRCIFLFCCREQP 88

Query: 85 CSTGGARSWKVFRSQ 99
          C  G     +VFR+Q
Sbjct: 89 CCAG----LRVFRNQ 99


>gi|150378478 PR domain containing 8 [Homo sapiens]
          Length = 689

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 8/88 (9%)

Query: 218 EGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLT 277
           EG+   +L+  +   D +E+  +  IK+G Q FY+ ++RIA  +E ++ Y      L L 
Sbjct: 84  EGLMWLRLVQSA--RDKEEQNLEAYIKNG-QLFYRSLRRIAKDEELLVWYGKELTELLLL 140

Query: 278 CPTSEVTELP-----ACSQCGGQRIFEF 300
           CP+    ++       C +C  +  FEF
Sbjct: 141 CPSRSHNKMNGSSPYTCLECSQRFQFEF 168


>gi|150378439 PR domain containing 8 [Homo sapiens]
          Length = 689

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 8/88 (9%)

Query: 218 EGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLT 277
           EG+   +L+  +   D +E+  +  IK+G Q FY+ ++RIA  +E ++ Y      L L 
Sbjct: 84  EGLMWLRLVQSA--RDKEEQNLEAYIKNG-QLFYRSLRRIAKDEELLVWYGKELTELLLL 140

Query: 278 CPTSEVTELP-----ACSQCGGQRIFEF 300
           CP+    ++       C +C  +  FEF
Sbjct: 141 CPSRSHNKMNGSSPYTCLECSQRFQFEF 168


>gi|32483412 connexin 40 [Homo sapiens]
          Length = 358

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 93  WKVFRSQCLQVPEREAQDAQKQGNSLAAEDWCEGADDWGSDTEEGPSPQFTLDFGNDASS 152
           WK  R + ++ P +     Q  G S+     C    D+    E GP  +F   F N+ +S
Sbjct: 231 WKKIRQRFVK-PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMAS 289

Query: 153 AKDVD 157
            ++ D
Sbjct: 290 QQNTD 294


>gi|6631083 connexin 40 [Homo sapiens]
          Length = 358

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 93  WKVFRSQCLQVPEREAQDAQKQGNSLAAEDWCEGADDWGSDTEEGPSPQFTLDFGNDASS 152
           WK  R + ++ P +     Q  G S+     C    D+    E GP  +F   F N+ +S
Sbjct: 231 WKKIRQRFVK-PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMAS 289

Query: 153 AKDVD 157
            ++ D
Sbjct: 290 QQNTD 294


>gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]
          Length = 857

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 18/59 (30%), Positives = 28/59 (47%)

Query: 105 EREAQDAQKQGNSLAAEDWCEGADDWGSDTEEGPSPQFTLDFGNDASSAKDVDWTARLQ 163
           E + Q+ Q +  S    +  EG    G DTEE  SP   LD  ++  S ++ +  A+ Q
Sbjct: 341 EEDVQEEQSKEASDPESNEEEGDSSGGEDTEESDSPDSHLDLESNVESEEENEKPAKEQ 399


>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
          Length = 186

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 15/72 (20%)

Query: 13  RDAPVHGSPTGPGAWTASKLGG----------IPDALP----TVAAPRPVCQRCGQPLAL 58
           ++AP    P  P  W  +   G          +P++LP    +V  P+P   RC +   L
Sbjct: 111 QEAPALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGL 170

Query: 59  VVQVYCPLEGSP 70
            ++V+ P  GSP
Sbjct: 171 GLRVWRPW-GSP 181


>gi|89040432 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 212

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 18/67 (26%)

Query: 11  GLRDAPVHGSP-----------TGPGAWTASKLGGIPDALPTVAAPRPVCQR------CG 53
           G R  PV  SP           + PGA   S +  +  +LP +AAPRP+  R        
Sbjct: 116 GARSRPVAASPAASSRARSRPESSPGA-PGSSVPALLPSLPPLAAPRPLSARPRLRPPQP 174

Query: 54  QPLALVV 60
           QPLAL V
Sbjct: 175 QPLALTV 181


>gi|239742637 PREDICTED: hypothetical protein XP_002342585 [Homo
           sapiens]
          Length = 91

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 13/44 (29%), Positives = 24/44 (54%)

Query: 195 EDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKY 238
           E+D + + +L+    LL D+ Q     MD  +   + +DGDE++
Sbjct: 21  EEDRKMWESLELPRDLLNDFDQNVHSDMDNKVQAEVVSDGDEEF 64


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score = 28.5 bits (62), Expect = 9.7
 Identities = 18/57 (31%), Positives = 20/57 (35%), Gaps = 7/57 (12%)

Query: 90  ARSWKVFRSQCLQVPEREAQDAQKQG-------NSLAAEDWCEGADDWGSDTEEGPS 139
           A  WK F      VP+R AQ     G           A   CEG + W   T  G S
Sbjct: 795 ADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLGDS 851


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,298,919
Number of Sequences: 37866
Number of extensions: 819353
Number of successful extensions: 2118
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2107
Number of HSP's gapped (non-prelim): 14
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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