Guide to the Human Genome
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Search of human proteins with 14150090

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14150090 chromosome 2 open reading frame 7 [Homo sapiens]
         (188 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14150090 chromosome 2 open reading frame 7 [Homo sapiens]          396   e-111
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [...    51   5e-07
gi|37675277 ring finger protein 148 [Homo sapiens]                     38   0.006
gi|21040269 ring finger protein 133 [Homo sapiens]                     36   0.017
gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo sa...    33   0.19 
gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo sap...    33   0.19 
gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]            33   0.19 
gi|37588871 ring finger protein 128 isoform 2 [Homo sapiens]           32   0.42 
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    30   0.94 
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ...    30   0.94 
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         30   1.2  
gi|29788758 ring finger protein 130 [Homo sapiens]                     30   1.6  
gi|115298678 complement component 3 precursor [Homo sapiens]           29   2.7  
gi|169214179 PREDICTED: similar to complement component 3 [Homo ...    29   2.7  
gi|37588873 ring finger protein 128 isoform 1 [Homo sapiens]           29   2.7  
gi|29789407 ring finger protein 149 [Homo sapiens]                     29   2.7  
gi|38524591 intramembrane protease 5 [Homo sapiens]                    28   4.7  
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    27   7.9  

>gi|14150090 chromosome 2 open reading frame 7 [Homo sapiens]
          Length = 188

 Score =  396 bits (1017), Expect = e-111
 Identities = 188/188 (100%), Positives = 188/188 (100%)

Query: 1   MVPGAAGWCCLVLWLPACVAAHGFRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRY 60
           MVPGAAGWCCLVLWLPACVAAHGFRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRY
Sbjct: 1   MVPGAAGWCCLVLWLPACVAAHGFRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRY 60

Query: 61  EQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVD 120
           EQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVD
Sbjct: 61  EQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVD 120

Query: 121 NDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFEL 180
           NDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFEL
Sbjct: 121 NDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFEL 180

Query: 181 LQPPWTFW 188
           LQPPWTFW
Sbjct: 181 LQPPWTFW 188


>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
           [Homo sapiens]
          Length = 932

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 4/123 (3%)

Query: 41  RYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSK 100
           R + TA PA+    +   +  +  +  ++P   C EL+N   +  +IAL++RG C F  K
Sbjct: 660 RVVLTAGPAQFGLDLSKHKETRGFVASSKPSNGCSELTNPEAVMGKIALIQRGQCMFAEK 719

Query: 101 TRVVQEHG--GRAVIISDNAVDNDSFYVEMIQDSTQRTAD--IPALFLLGRDGYMIRRSL 156
            R +Q  G  G  VI  +    +D+  +  +    + T D  IP LFL  ++G +I  ++
Sbjct: 720 ARNIQNAGAIGGIVIDDNEGSSSDTAPLFQMAGDGKDTDDIKIPMLFLFSKEGSIILDAI 779

Query: 157 EQH 159
            ++
Sbjct: 780 REY 782


>gi|37675277 ring finger protein 148 [Homo sapiens]
          Length = 305

 Score = 37.7 bits (86), Expect = 0.006
 Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 54  GIF--HTRYEQIHLVPAEPP----EACGELSNGFFIQDQ----IALVERGGCSFLSKTRV 103
           G+F  H+  E++  V A P      AC  L+N F    Q    +AL+ERGGC+F  K  V
Sbjct: 60  GVFGNHSPLERVSGVVALPEGWNQNACHPLTN-FSRPKQADSWLALIERGGCTFTHKINV 118

Query: 104 VQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPW 163
             E G   VII +          ++   S Q T +I A+ +    G  I  S+++     
Sbjct: 119 AAEKGANGVIIYNYQGTGS----KVFPMSHQGTENIVAVMISNLKGMEILHSIQKGVYVT 174

Query: 164 AIISI 168
            II +
Sbjct: 175 VIIEV 179


>gi|21040269 ring finger protein 133 [Homo sapiens]
          Length = 376

 Score = 36.2 bits (82), Expect = 0.017
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 8/53 (15%)

Query: 70  PPE-----ACGE---LSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVII 114
           PPE     AC      S   + +  +AL+ERGGC+F  K +V  E G   VII
Sbjct: 77  PPEGKIQNACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVATEKGASGVII 129


>gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo
           sapiens]
          Length = 511

 Score = 32.7 bits (73), Expect = 0.19
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 85  DQIALVERGGCSFLSKTRVVQEHGGRAVII 114
           +QI LV RG C+F  K R+ Q  G R ++I
Sbjct: 88  NQIPLVARGNCTFYEKVRLAQGSGARGLLI 117


>gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo
           sapiens]
          Length = 592

 Score = 32.7 bits (73), Expect = 0.19
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 85  DQIALVERGGCSFLSKTRVVQEHGGRAVII 114
           +QI LV RG C+F  K R+ Q  G R ++I
Sbjct: 88  NQIPLVARGNCTFYEKVRLAQGSGARGLLI 117


>gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
          Length = 520

 Score = 32.7 bits (73), Expect = 0.19
 Identities = 13/37 (35%), Positives = 23/37 (62%)

Query: 83  IQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAV 119
           I+ +  +V  G C FL K R+ Q+ G  A+++ +N+V
Sbjct: 83  IKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSV 119


>gi|37588871 ring finger protein 128 isoform 2 [Homo sapiens]
          Length = 402

 Score = 31.6 bits (70), Expect = 0.42
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%)

Query: 87  IALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLG 146
           IAL+ERG C+F  K +        AV+I  NA +  +   + IQ +     DI A+ +  
Sbjct: 92  IALIERGNCTFSEKIQTAGRRNADAVVIY-NAPETGN---QTIQMANFGAVDIVAIMIGN 147

Query: 147 RDGYMIRRSLEQ 158
             G  I +S+++
Sbjct: 148 LKGTKILQSIQR 159


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 30.4 bits (67), Expect = 0.94
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 12/81 (14%)

Query: 33  QVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEA-------CGELSN-GFFIQ 84
           +V +PG   Y+F+   AKD    +H + E + L+  +  +        CG+ ++ G+   
Sbjct: 128 EVANPGSFIYVFSDARAKD----YHKKEELLRLLQLKQSQVVFVLTGDCGDRTHPGYLAY 183

Query: 85  DQIALVERGGCSFLSKTRVVQ 105
           ++IA    G    L K +V +
Sbjct: 184 EEIAATSSGQVFHLDKQQVTE 204


>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
           sapiens]
          Length = 790

 Score = 30.4 bits (67), Expect = 0.94
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 12/81 (14%)

Query: 33  QVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEA-------CGELSN-GFFIQ 84
           +V +PG   Y+F+   AKD    +H + E + L+  +  +        CG+ ++ G+   
Sbjct: 127 EVANPGSFIYVFSDARAKD----YHKKEELLRLLQLKQSQVVFVLTGDCGDRTHPGYLAY 182

Query: 85  DQIALVERGGCSFLSKTRVVQ 105
           ++IA    G    L K +V +
Sbjct: 183 EEIAATSSGQVFHLDKQQVTE 203


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 30.0 bits (66), Expect = 1.2
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 12/81 (14%)

Query: 33  QVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEA-------CGELSN-GFFIQ 84
           +V +PG   Y+F+   AKD    +H + E + L+  +  +        CG+ ++ G+   
Sbjct: 11  EVANPGSFIYVFSDARAKD----YHKKEELLRLLQLKQSQVVFVLTGDCGDHTHPGYLAY 66

Query: 85  DQIALVERGGCSFLSKTRVVQ 105
           ++IA    G    L K +V +
Sbjct: 67  EEIAATSSGQVFHLDKQQVTE 87


>gi|29788758 ring finger protein 130 [Homo sapiens]
          Length = 419

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 83  IQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPAL 142
           I+  IAL++RG C+F  K      H   AV+I +N         E +  +   T DI A+
Sbjct: 101 IKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKE-----EPVTMTHPGTGDIIAV 155

Query: 143 FLLGRDGYMIRRSLEQH 159
            +    G  I   LE++
Sbjct: 156 MITELRGKDILSYLEKN 172


>gi|115298678 complement component 3 precursor [Homo sapiens]
          Length = 1663

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 9/91 (9%)

Query: 24   FRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFI 83
            F++H Y   +++ PG ++        +     +H   E   L      E C       FI
Sbjct: 1461 FKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFI 1520

Query: 84   Q---DQIALVER------GGCSFLSKTRVVQ 105
            Q   D++ L ER       G  ++ KTR+V+
Sbjct: 1521 QKSDDKVTLEERLDKACEPGVDYVYKTRLVK 1551


>gi|169214179 PREDICTED: similar to complement component 3 [Homo
           sapiens]
          Length = 390

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 9/91 (9%)

Query: 24  FRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFI 83
           F++H Y   +++ PG ++        +     +H   E   L      E C       FI
Sbjct: 188 FKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFI 247

Query: 84  Q---DQIALVER------GGCSFLSKTRVVQ 105
           Q   D++ L ER       G  ++ KTR+V+
Sbjct: 248 QKSDDKVTLEERLDKACEPGVDYVYKTRLVK 278


>gi|37588873 ring finger protein 128 isoform 1 [Homo sapiens]
          Length = 428

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 18/107 (16%)

Query: 65  LVPAEPP---EACGELSN-------GFFIQ-DQIALVERGG-CSFLSKTRVVQEHGGR-A 111
           LVP + P    AC   +N       G  +Q   +AL++RGG C+F  K  +  E G   A
Sbjct: 84  LVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGA 143

Query: 112 VIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQ 158
           VI +     N     E+I  S     DI A+ +    G  I +S+++
Sbjct: 144 VIFNFPGTRN-----EVIPMSHPGAVDIVAIMIGNLKGTKILQSIQR 185


>gi|29789407 ring finger protein 149 [Homo sapiens]
          Length = 400

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 12/28 (42%), Positives = 16/28 (57%)

Query: 87  IALVERGGCSFLSKTRVVQEHGGRAVII 114
           +ALV RGGC+F  K  V       AV++
Sbjct: 110 VALVARGGCTFKDKVLVAARRNASAVVL 137


>gi|38524591 intramembrane protease 5 [Homo sapiens]
          Length = 684

 Score = 28.1 bits (61), Expect = 4.7
 Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 83  IQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMI-QDSTQRTADI 139
           ++   A+V RG CSF +K  + Q  G   ++I     D       +  QD  Q  AD+
Sbjct: 89  LRQTTAMVMRGNCSFHTKGWLAQGQGAHGLLIVSRVSDQQCSDTTLAPQDPRQPLADL 146


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 10/24 (41%), Positives = 16/24 (66%)

Query: 65   LVPAEPPEACGELSNGFFIQDQIA 88
            L P  PP AC +++NGF   +++A
Sbjct: 3904 LPPTPPPMACQKMANGFATTEELA 3927


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.142    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,807,668
Number of Sequences: 37866
Number of extensions: 328344
Number of successful extensions: 746
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 732
Number of HSP's gapped (non-prelim): 21
length of query: 188
length of database: 18,247,518
effective HSP length: 96
effective length of query: 92
effective length of database: 14,612,382
effective search space: 1344339144
effective search space used: 1344339144
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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