BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14149696 SEC31 homolog B [Homo sapiens] (1179 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14149696 SEC31 homolog B [Homo sapiens] 2384 0.0 gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 1062 0.0 gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 1062 0.0 gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] 1060 0.0 gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 1046 0.0 gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] 1022 0.0 gi|47132519 Ras association and pleckstrin homology domains 1 is... 75 5e-13 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 71 5e-12 gi|160707881 formin 2 [Homo sapiens] 71 7e-12 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 70 9e-12 gi|163965366 nascent polypeptide-associated complex alpha subuni... 69 2e-11 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 67 8e-11 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 66 2e-10 gi|41281612 zinc finger protein 828 [Homo sapiens] 65 4e-10 gi|58331266 WD repeat domain 59 [Homo sapiens] 65 4e-10 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 63 2e-09 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 63 2e-09 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 63 2e-09 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 62 3e-09 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 62 4e-09 gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 60 9e-09 gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 60 9e-09 gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 60 9e-09 gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 60 9e-09 gi|117938768 GNAS complex locus alex [Homo sapiens] 59 2e-08 gi|40807452 peroxisome proliferator-activated receptor gamma, co... 59 2e-08 gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 59 2e-08 gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 59 2e-08 gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 59 2e-08 gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 59 2e-08 >gi|14149696 SEC31 homolog B [Homo sapiens] Length = 1179 Score = 2384 bits (6178), Expect = 0.0 Identities = 1179/1179 (100%), Positives = 1179/1179 (100%) Query: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR Sbjct: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 Query: 61 GVLSALSRFHKLVWGSFGSGLLESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKH 120 GVLSALSRFHKLVWGSFGSGLLESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKH Sbjct: 61 GVLSALSRFHKLVWGSFGSGLLESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKH 120 Query: 121 TGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQA 180 TGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQA Sbjct: 121 TGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQA 180 Query: 181 QHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPV 240 QHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPV Sbjct: 181 QHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPV 240 Query: 241 IQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKLP 300 IQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKLP Sbjct: 241 IQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKLP 300 Query: 301 TQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSKGQPLP 360 TQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSKGQPLP Sbjct: 301 TQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSKGQPLP 360 Query: 361 PLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAHLVPQPCPRLVF 420 PLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAHLVPQPCPRLVF Sbjct: 361 PLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAHLVPQPCPRLVF 420 Query: 421 ISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKVTLEQDSRMK 480 ISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKVTLEQDSRMK Sbjct: 421 ISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKVTLEQDSRMK 480 Query: 481 FLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQASKHTTKEASAS 540 FLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQASKHTTKEASAS Sbjct: 481 FLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQASKHTTKEASAS 540 Query: 541 SAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEERFADAIILAQAGG 600 SAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEERFADAIILAQAGG Sbjct: 541 SAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEERFADAIILAQAGG 600 Query: 601 TDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALALLLTYSGTEKFP 660 TDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALALLLTYSGTEKFP Sbjct: 601 TDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALALLLTYSGTEKFP 660 Query: 661 ELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSPMALQDLMEKVMV 720 ELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSPMALQDLMEKVMV Sbjct: 661 ELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSPMALQDLMEKVMV 720 Query: 721 LNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRL 780 LNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRL Sbjct: 721 LNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRL 780 Query: 781 FHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSS 840 FHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSS Sbjct: 781 FHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSS 840 Query: 841 PAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPN 900 PAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPN Sbjct: 841 PAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPN 900 Query: 901 PVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPAS 960 PVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPAS Sbjct: 901 PVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPAS 960 Query: 961 FPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPIT 1020 FPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPIT Sbjct: 961 FPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPIT 1020 Query: 1021 APVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKS 1080 APVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKS Sbjct: 1021 APVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKS 1080 Query: 1081 SFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEVARCVDAGS 1140 SFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEVARCVDAGS Sbjct: 1081 SFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEVARCVDAGS 1140 Query: 1141 FEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV 1179 FEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV Sbjct: 1141 FEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV 1179 >gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] Length = 1220 Score = 1062 bits (2746), Expect = 0.0 Identities = 590/1257 (46%), Positives = 783/1257 (62%), Gaps = 119/1257 (9%) Query: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 MKLKE++R A+QAWSPA +P+YLATGTSAQQLD++FSTN +LEIFE+D DPSLD+K Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 GVLSALSRFHKLVWGSFGSGLL-ESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 119 S+ R+HKL+WG + + SGV++ GG+NG +ILY+ + I++ KE VIAQ K Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 120 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 179 HTG VRALD+N FQ NL+ASGA++SEI+IWDLNN PMT G+K+Q PPEDI ++WNRQ Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ 179 Query: 180 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 239 QHIL+SA PSG+A VWDLRKNEPIIKVSDHSNRMHCSGLAWHPD+ATQ+VL SEDDRLP Sbjct: 180 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239 Query: 240 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 299 VIQ+WDLRFASSPL+VLE+H+RGIL+++WS AD ELLL+ KD++ILC N + EV+Y+L Sbjct: 240 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299 Query: 300 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 355 PT + WCFD+QWCPR+P+V SAASF+G IS+YS+MG S + +Q DK+SSSF Sbjct: 300 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF 359 Query: 356 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAH--LV 411 GQPLPPLQ+P+Q AQ ++ PLKKPPKWIRRP G SF+FGGKLVTF P+H Sbjct: 360 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE 419 Query: 412 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 471 Q VFISQV TE EFL RS +LQ+A+ S +NYCQ K + + EK +W FLKV Sbjct: 420 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV 479 Query: 472 TLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQAS- 530 E DSR K+L+LLGY K++L KK+A L G + + SD +++ ++ Sbjct: 480 NFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQL 539 Query: 531 --KHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEER 588 +H +E S E +P + + I ++ DIDGL++QALL G AV+LCL + R Sbjct: 540 LGEHIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNR 594 Query: 589 FADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALA 648 ADAIILA AGG +LL +TQ++Y AK ++KI+ L+ VV KNWK++V +C LKNWREALA Sbjct: 595 MADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALA 654 Query: 649 LLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSP 708 +LTY+ ++F LCD+LGTR+E EG L ++A LCY+C+G+VE+LV CW K P Sbjct: 655 AVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHP 714 Query: 709 MALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDC 768 ++LQDL+EKV++L ++++ + + G +++QYANLLAAQGS+A A++FLP + Sbjct: 715 LSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNT 774 Query: 769 AQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTP 828 QP + QLRDRL AQG V G +SP P+ + ++ R G H Sbjct: 775 NQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH---- 821 Query: 829 SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP 888 PRV T Q P +P P N++ P A LP SPG P Sbjct: 822 -QMPRVQTQQYYPH----GENPPPPGFIMHGNVN------PNAAGQLPTSPGHMHTQVPP 870 Query: 889 QLLGGQRVQVPNPVGFPGTWPLP----GSPLPMACPGIMRPGSTSLPETPRLFPLLPLRP 944 P P + P P GS + + P S + P TP + Sbjct: 871 Y---------PQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTG 921 Query: 945 LGPGRMVSH-----TPAPPASFPVP------YLPGDPGAPCSS---VLP--TTGIL---- 984 H T +P SFP P + G PGAP SS LP TTG L Sbjct: 922 QSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAAS 981 Query: 985 ----TPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGIL----PS 1036 + GPQ+ W + PA ++ K+PE FMPP PIT+P+M+ + Q + PS Sbjct: 982 ELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPS 1041 Query: 1037 QP-PVSSVSHAP----------------------------------PGVP-GELSLQLQH 1060 P P+SS S P PG P G +Q Sbjct: 1042 APVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQS 1101 Query: 1061 LPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGT 1120 LP +K+ +K +P EH LK++FE L+QRC SATD +TKRKL++A++RLE+LY+KL E T Sbjct: 1102 LPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQT 1161 Query: 1121 LSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKL 1177 LSP + +GLH +AR ++ ++ +GL +H + S+FSE S+FMP+LK VL A+KL Sbjct: 1162 LSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKL 1218 >gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] Length = 1220 Score = 1062 bits (2746), Expect = 0.0 Identities = 590/1257 (46%), Positives = 783/1257 (62%), Gaps = 119/1257 (9%) Query: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 MKLKE++R A+QAWSPA +P+YLATGTSAQQLD++FSTN +LEIFE+D DPSLD+K Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 GVLSALSRFHKLVWGSFGSGLL-ESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 119 S+ R+HKL+WG + + SGV++ GG+NG +ILY+ + I++ KE VIAQ K Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 120 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 179 HTG VRALD+N FQ NL+ASGA++SEI+IWDLNN PMT G+K+Q PPEDI ++WNRQ Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ 179 Query: 180 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 239 QHIL+SA PSG+A VWDLRKNEPIIKVSDHSNRMHCSGLAWHPD+ATQ+VL SEDDRLP Sbjct: 180 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239 Query: 240 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 299 VIQ+WDLRFASSPL+VLE+H+RGIL+++WS AD ELLL+ KD++ILC N + EV+Y+L Sbjct: 240 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299 Query: 300 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 355 PT + WCFD+QWCPR+P+V SAASF+G IS+YS+MG S + +Q DK+SSSF Sbjct: 300 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF 359 Query: 356 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAH--LV 411 GQPLPPLQ+P+Q AQ ++ PLKKPPKWIRRP G SF+FGGKLVTF P+H Sbjct: 360 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE 419 Query: 412 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 471 Q VFISQV TE EFL RS +LQ+A+ S +NYCQ K + + EK +W FLKV Sbjct: 420 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV 479 Query: 472 TLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQAS- 530 E DSR K+L+LLGY K++L KK+A L G + + SD +++ ++ Sbjct: 480 NFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQL 539 Query: 531 --KHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEER 588 +H +E S E +P + + I ++ DIDGL++QALL G AV+LCL + R Sbjct: 540 LGEHIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNR 594 Query: 589 FADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALA 648 ADAIILA AGG +LL +TQ++Y AK ++KI+ L+ VV KNWK++V +C LKNWREALA Sbjct: 595 MADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALA 654 Query: 649 LLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSP 708 +LTY+ ++F LCD+LGTR+E EG L ++A LCY+C+G+VE+LV CW K P Sbjct: 655 AVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHP 714 Query: 709 MALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDC 768 ++LQDL+EKV++L ++++ + + G +++QYANLLAAQGS+A A++FLP + Sbjct: 715 LSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNT 774 Query: 769 AQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTP 828 QP + QLRDRL AQG V G +SP P+ + ++ R G H Sbjct: 775 NQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH---- 821 Query: 829 SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP 888 PRV T Q P +P P N++ P A LP SPG P Sbjct: 822 -QMPRVQTQQYYPH----GENPPPPGFIMHGNVN------PNAAGQLPTSPGHMHTQVPP 870 Query: 889 QLLGGQRVQVPNPVGFPGTWPLP----GSPLPMACPGIMRPGSTSLPETPRLFPLLPLRP 944 P P + P P GS + + P S + P TP + Sbjct: 871 Y---------PQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTG 921 Query: 945 LGPGRMVSH-----TPAPPASFPVP------YLPGDPGAPCSS---VLP--TTGIL---- 984 H T +P SFP P + G PGAP SS LP TTG L Sbjct: 922 QSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAAS 981 Query: 985 ----TPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGIL----PS 1036 + GPQ+ W + PA ++ K+PE FMPP PIT+P+M+ + Q + PS Sbjct: 982 ELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPS 1041 Query: 1037 QP-PVSSVSHAP----------------------------------PGVP-GELSLQLQH 1060 P P+SS S P PG P G +Q Sbjct: 1042 APVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQS 1101 Query: 1061 LPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGT 1120 LP +K+ +K +P EH LK++FE L+QRC SATD +TKRKL++A++RLE+LY+KL E T Sbjct: 1102 LPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQT 1161 Query: 1121 LSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKL 1177 LSP + +GLH +AR ++ ++ +GL +H + S+FSE S+FMP+LK VL A+KL Sbjct: 1162 LSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKL 1218 >gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] Length = 1205 Score = 1060 bits (2741), Expect = 0.0 Identities = 586/1245 (47%), Positives = 779/1245 (62%), Gaps = 110/1245 (8%) Query: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 MKLKE++R A+QAWSPA +P+YLATGTSAQQLD++FSTN +LEIFE+D DPSLD+K Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 GVLSALSRFHKLVWGSFGSGLL-ESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 119 S+ R+HKL+WG + + SGV++ GG+NG +ILY+ + I++ KE VIAQ K Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 120 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 179 HTG VRALD+N FQ NL+ASGA++SEI+IWDLNN PMT G+K+Q PPEDI ++WNRQ Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ 179 Query: 180 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 239 QHIL+SA PSG+A VWDLRKNEPIIKVSDHSNRMHCSGLAWHPD+ATQ+VL SEDDRLP Sbjct: 180 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239 Query: 240 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 299 VIQ+WDLRFASSPL+VLE+H+RGIL+++WS AD ELLL+ KD++ILC N + EV+Y+L Sbjct: 240 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299 Query: 300 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 355 PT + WCFD+QWCPR+P+V SAASF+G IS+YS+MG S + +Q DK+SSSF Sbjct: 300 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF 359 Query: 356 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAH--LV 411 GQPLPPLQ+P+Q AQ ++ PLKKPPKWIRRP G SF+FGGKLVTF P+H Sbjct: 360 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE 419 Query: 412 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 471 Q VFISQV TE EFL RS +LQ+A+ S +NYCQ K + + EK +W FLKV Sbjct: 420 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV 479 Query: 472 TLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQAS- 530 E DSR K+L+LLGY K++L KK+A L G + + SD +++ ++ Sbjct: 480 NFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQL 539 Query: 531 --KHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEER 588 +H +E S E +P + + I ++ DIDGL++QALL G AV+LCL + R Sbjct: 540 LGEHIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNR 594 Query: 589 FADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALA 648 ADAIILA AGG +LL +TQ++Y AK ++KI+ L+ VV KNWK++V +C LKNWREALA Sbjct: 595 MADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALA 654 Query: 649 LLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSP 708 +LTY+ ++F LCD+LGTR+E EG L ++A LCY+C+G+VE+LV CW K P Sbjct: 655 AVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHP 714 Query: 709 MALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDC 768 ++LQDL+EKV++L ++++ + + G +++QYANLLAAQGS+A A++FLP + Sbjct: 715 LSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNT 774 Query: 769 AQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTP 828 QP + QLRDRL AQG V G +SP P+ + ++ R G H Sbjct: 775 NQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH---- 821 Query: 829 SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP 888 PRV T Q P +P P N++ P A LP SPG P Sbjct: 822 -QMPRVQTQQYYPH----GENPPPPGFIMHGNVN------PNAAGQLPTSPGHMHTQVPP 870 Query: 889 QLLGGQRVQVPNPVGFPGTWPLP----GSPLPMACPGIMRPGSTSLPETPRLFPLLPLRP 944 P P + P P GS + + P S + P TP + Sbjct: 871 Y---------PQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTG 921 Query: 945 LGPGRMVSH-----TPAPPASFPVP------YLPGDPGAPCSSVLPTTGILTPHP-GPQD 992 H T +P SFP P + G PGAP SS + L P GPQ+ Sbjct: 922 QSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSS---SAYALPPGTTGPQN 978 Query: 993 SWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGIL----PSQP-PVSSVSHAP 1047 W + PA ++ K+PE FMPP PIT+P+M+ + Q + PS P P+SS S P Sbjct: 979 GWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFP 1038 Query: 1048 ----------------------------------PGVP-GELSLQLQHLPPEKMERKELP 1072 PG P G +Q LP +K+ +K +P Sbjct: 1039 QPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIP 1098 Query: 1073 PEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEV 1132 EH LK++FE L+QRC SATD +TKRKL++A++RLE+LY+KL E TLSP + +GLH + Sbjct: 1099 DEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNI 1158 Query: 1133 ARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKL 1177 AR ++ ++ +GL +H + S+FSE S+FMP+LK VL A+KL Sbjct: 1159 ARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKL 1203 >gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] Length = 1181 Score = 1046 bits (2704), Expect = 0.0 Identities = 585/1254 (46%), Positives = 769/1254 (61%), Gaps = 152/1254 (12%) Query: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 MKLKE++R A+QAWSPA +P+YLATGTSAQQLD++FSTN +LEIFE+D DPSLD+K Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 GVLSALSRFHKLVWGSFGSGLL-ESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 119 S+ R+HKL+WG + + SGV++ GG+NG +ILY+ + I++ KE VIAQ K Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 120 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 179 HTG VRALD+N FQ NL+ASGA++SEI+IWDLNN PMT G+K+Q PPEDI ++WNRQ Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ 179 Query: 180 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 239 QHIL+SA PSG+A VWDLRKNEPIIKVSDHSNRMHCSGLAWHPD+ATQ+VL SEDDRLP Sbjct: 180 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239 Query: 240 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 299 VIQ+WDLRFASSPL+VLE+H+RGIL+++WS AD ELLL+ KD++ILC N + EV+Y+L Sbjct: 240 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299 Query: 300 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 355 PT + WCFD+QWCPR+P+V SAASF+G IS+YS+MG S + +Q DK+SSSF Sbjct: 300 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF 359 Query: 356 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAH--LV 411 GQPLPPLQ+P+Q AQ ++ PLKKPPKWIRRP G SF+FGGKLVTF P+H Sbjct: 360 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE 419 Query: 412 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 471 Q VFISQV TE EFL RS +LQ+A+ S +NYCQ K + + EK +W FLKV Sbjct: 420 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV 479 Query: 472 TLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQASK 531 E DSR K+L+LLGY K++L K K Sbjct: 480 NFEDDSRGKYLELLGYRKEDLGK------------------------------------K 503 Query: 532 HTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEERFAD 591 H +E S E +P + + I ++ DIDGL++QALL G AV+LCL + R AD Sbjct: 504 HIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMAD 558 Query: 592 AIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALALLL 651 AIILA AGG +LL +TQ++Y AK ++KI+ L+ VV KNWK++V +C LKNWREALA +L Sbjct: 559 AIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVL 618 Query: 652 TYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSPMAL 711 TY+ ++F LCD+LGTR+E EG L ++A LCY+C+G+VE+LV CW K P++L Sbjct: 619 TYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSL 678 Query: 712 QDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQP 771 QDL+EKV++L ++++ + + G +++QYANLLAAQGS+A A++FLP + QP Sbjct: 679 QDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQP 738 Query: 772 PVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPR 831 + QLRDRL AQG V G +SP P+ + ++ R G H Sbjct: 739 NIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH-----QM 784 Query: 832 PRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLL 891 PRV T Q P +P P N++ P A LP SPG P Sbjct: 785 PRVQTQQYYP----HGENPPPPGFIMHGNVN------PNAAGQLPTSPGHMHTQVPP--- 831 Query: 892 GGQRVQVPNPVGFPGTWPLP----GSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGP 947 P P + P P GS + + P S + P TP + Sbjct: 832 ------YPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQ 885 Query: 948 GRMVSH-----TPAPPASFPVP------YLPGDPGAPCSS---VLP--TTGIL------- 984 H T +P SFP P + G PGAP SS LP TTG L Sbjct: 886 LYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELP 945 Query: 985 -TPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQG-ILPSQP---- 1038 + GPQ+ W + PA ++ K+PE FMPP PIT+P+M+ + Q +L QP Sbjct: 946 ASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPV 1005 Query: 1039 PVSSVSHAP----------------------------------PGVP-GELSLQLQHLPP 1063 P+SS S P PG P G +Q LP Sbjct: 1006 PLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPT 1065 Query: 1064 EKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSP 1123 +K+ +K +P EH LK++FE L+QRC SATD +TKRKL++A++RLE+LY+KL E TLSP Sbjct: 1066 KKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLSP 1125 Query: 1124 HVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKL 1177 + +GLH +AR ++ ++ +GL +H + S+FSE S+FMP+LK VL A+KL Sbjct: 1126 TITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKL 1179 >gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] Length = 1106 Score = 1022 bits (2643), Expect = 0.0 Identities = 564/1198 (47%), Positives = 752/1198 (62%), Gaps = 115/1198 (9%) Query: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 MKLKE++R A+QAWSPA +P+YLATGTSAQQLD++FSTN +LEIFE+D DPSLD+K Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 GVLSALSRFHKLVWGSFGSGLL-ESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 119 S+ R+HKL+WG + + SGV++ GG+NG +ILY+ + I++ KE VIAQ K Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 120 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 179 HTG VRALD+N FQ NL+ASGA++SEI+IWDLNN PMT G+K+Q PPEDI ++WNRQ Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ 179 Query: 180 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 239 QHIL+SA PSG+A VWDLRKNEPIIKVSDHSNRMHCSGLAWHPD+ATQ+VL SEDDRLP Sbjct: 180 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239 Query: 240 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 299 VIQ+WDLRFASSPL+VLE+H+RGIL+++WS AD ELLL+ KD++ILC N + EV+Y+L Sbjct: 240 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299 Query: 300 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 355 PT + WCFD+QWCPR+P+V SAASF+G IS+YS+MG S + +Q DK+SSSF Sbjct: 300 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF 359 Query: 356 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAH--LV 411 GQPLPPLQ+P+Q AQ ++ PLKKPPKWIRRP G SF+FGGKLVTF P+H Sbjct: 360 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE 419 Query: 412 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 471 Q VFISQV TE EFL RS +LQ+A+ S +NYCQ K + + EK +W FLKV Sbjct: 420 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV 479 Query: 472 TLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQ--- 528 E DSR K+L+LLGY K++L KK+A L G + + SD +++ ++ Sbjct: 480 NFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQL 539 Query: 529 ASKHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEER 588 +H +E S E +P + + I ++ DIDGL++QALL G AV+LCL + R Sbjct: 540 LGEHIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNR 594 Query: 589 FADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALA 648 ADAIILA AGG +LL +TQ++Y AK ++KI+ L+ VV KNWK++V +C LKNWREALA Sbjct: 595 MADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALA 654 Query: 649 LLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSP 708 +LTY+ ++F LCD+LGTR+E EG L ++A LCY+C+G+VE+LV CW K P Sbjct: 655 AVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHP 714 Query: 709 MALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDC 768 ++LQDL+EKV++L ++++ + + G +++QYANLLAAQGS+A A++FLP + Sbjct: 715 LSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNT 774 Query: 769 AQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTP 828 QP + QLRDRL AQG V G +SP P+ + ++ R G H Sbjct: 775 NQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH---- 821 Query: 829 SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP 888 PRV T Q P +P P N++ P A LP SPG P Sbjct: 822 -QMPRVQTQQYYP----HGENPPPPGFIMHGNVN------PNAAGQLPTSPGHMHTQVPP 870 Query: 889 QLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLG-- 946 P P W P P P + +P P P+ + PLG Sbjct: 871 ---------YPQPQRPQNGWNDP--PALNRVPKKKKMPENFMPPVPITSPI--MNPLGDP 917 Query: 947 PGRMVSHTPAPP------ASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAP 1000 +M+ P+ P +SFP P+LPG P G+ P Sbjct: 918 QSQMLQQQPSAPVPLSSQSSFPQPHLPGGQ--------PFHGVQQP-------------- 955 Query: 1001 RGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVP-GELSLQLQ 1059 L +T MPP+ P ++G PG P G +Q Sbjct: 956 --------LGQTGMPPS-------FSKPNIEG--------------APGAPIGNTFQHVQ 986 Query: 1060 HLPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEG 1119 LP +K+ +K +P EH LK++FE L+QRC SATD +TKRKL++A++RLE+LY+KL E Sbjct: 987 SLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQ 1046 Query: 1120 TLSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKL 1177 TLSP + +GLH +AR ++ ++ +GL +H + S+FSE S+FMP+LK VL A+KL Sbjct: 1047 TLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKL 1104 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 74.7 bits (182), Expect = 5e-13 Identities = 83/295 (28%), Positives = 117/295 (39%), Gaps = 28/295 (9%) Query: 797 PFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQG- 855 P+ +V + K + Y SQPS +P P P P P P P PS +P G Sbjct: 601 PYTSLVPPLSPQPKIVTPYT-ASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGS 659 Query: 856 -----------PRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGF 904 R QN S + A+ P P ++ S +PQ+L VP P Sbjct: 660 AAPMFVKYSTITRLQNASQHSG----ALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP- 714 Query: 905 PGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVS-HTPAPPASFPV 963 P P PGS + P P + SLP+ P L + + V+ TP PP P Sbjct: 715 PPPPPTPGSAMAQLKPA---PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA 771 Query: 964 PYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNK--LPETFMPPAPITA 1021 P P P P ++ T T P + P P + + P +++PP+P T Sbjct: 772 PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP 831 Query: 1022 PVMSLTPEL--QGILPSQPPVSSVSHAPPGVPGELSLQLQHLP-PEKMERKELPP 1073 PV P L Q ++PP S +S P V +++ Q P P ME + L P Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSPLSPV-PSVVKQIASQFPPPPTPPAMESQPLKP 885 Score = 49.3 bits (116), Expect = 2e-05 Identities = 68/261 (26%), Positives = 94/261 (36%), Gaps = 52/261 (19%) Query: 821 PSHQVPTPSPRPRVFTPQSS----------PAMPLAPSHPSPYQGPRTQNISDYRAPGPQ 870 P+ VP P P P TP S+ P++P + P P + + Q+I+ P P Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764 Query: 871 AIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPL-----PGSPLPMACPGIMRP 925 P P P P + P+ L V +P P P+ P +P P P +P Sbjct: 765 ---PPPPIPAPLPPQAPPKPL----VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQP 817 Query: 926 G--STSLPETPRLFPLLPLRPLGPGRMVSHTPAPPAS--FPVPYL--------PGDPGAP 973 ++ +P +P P +P+ P + S PP S PVP + P P P Sbjct: 818 AFPASYIPPSPPT-PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876 Query: 974 CSSVLPTTGILTPHPG---PQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPEL 1030 P L P P PQ P+ +P PP P PE Sbjct: 877 AMESQP----LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP---------PES 923 Query: 1031 QGILPSQPPVSSVSHAPPGVP 1051 + P PP S V PP P Sbjct: 924 SLVFPPPPP-SPVPAPPPPPP 943 Score = 40.8 bits (94), Expect = 0.008 Identities = 78/309 (25%), Positives = 106/309 (34%), Gaps = 31/309 (10%) Query: 762 SFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVG-ATLHSKETSSYRLGSQ 820 S++P PPV L Q SP P P +V A+ + + SQ Sbjct: 822 SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881 Query: 821 PSHQVPT---PSPRPRVFT-PQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLP 876 P VP P P V P+ P+ PS P P + + P P P P Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 Query: 877 LSPGVRPASSQPQLLGGQRVQVPNPVG-FPGTWPLPGSPLPMAC----PGIMRPGSTSLP 931 P P + G + + +P G P P S + + P RP SL Sbjct: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLV 1001 Query: 932 E--TPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHP- 988 TP P G T PPA+ P P G VL + P Sbjct: 1002 SKFTP---------PAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPV 1052 Query: 989 ---GPQDSWKEAPAPRGNLQ-RNKLPETFMPPAPITAPVM---SLTPELQGI--LPSQPP 1039 +DS E P+P + PET +P PI P + + +P++ + P Q Sbjct: 1053 LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112 Query: 1040 VSSVSHAPP 1048 SV APP Sbjct: 1113 KMSVKKAPP 1121 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 71.2 bits (173), Expect = 5e-12 Identities = 104/400 (26%), Positives = 140/400 (35%), Gaps = 83/400 (20%) Query: 739 ATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPV-------QQLRDRLFHAQGSAVLG- 790 +T Y +Q + GSLA A + PPV Q L + Q +A G Sbjct: 622 STVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGL 681 Query: 791 -------QQSPP-----FPFPRIVVGATLHSKETSSYRLGSQPS---HQVPT---PSPRP 832 PP FP P + L T QP+ Q P P+P P Sbjct: 682 PVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLP 741 Query: 833 RVFTPQSSPAMPL--APSHPSPYQGPRTQ-----NISDYRAPG---------PQAIQPLP 876 +V PQ P +PL P H PY P +Q + + P P + P+P Sbjct: 742 QVLAPQ--PVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIP 799 Query: 877 LSPGVRPAS-------SQPQLLGGQRVQVPNPVGFPGTWPLP--GSPLPMACPG------ 921 + P + P + + P L VP P F LP +PLP A P Sbjct: 800 VVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAV 859 Query: 922 ---------IMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGA 972 + P T +P P PLL + P G + H+ V LPG P Sbjct: 860 KLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHS-------AVAQLPGQPVY 912 Query: 973 PCS--SVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPE- 1029 P + + PT +PH Q+ P P Q P+ +PP P P L P+ Sbjct: 913 PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQP 972 Query: 1030 ---LQGILPSQP--PVSSVSHAPPGVPGELSLQLQHLPPE 1064 Q +LP QP P V P +P HLP + Sbjct: 973 TRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQ 1012 Score = 58.5 bits (140), Expect = 4e-08 Identities = 120/449 (26%), Positives = 157/449 (34%), Gaps = 100/449 (22%) Query: 725 LEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQ 784 L Q+ P V P + Y LA + P Q P+Q L Sbjct: 740 LPQVLAPQPVVPLQPVPPHLPPY---LAPASQVGAPAQLKPLQMPQAPLQPL-------- 788 Query: 785 GSAVLGQQSPPFPF-PRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQ---SS 840 A + Q PP P P I A + + L P+ VP P P P+ F+P S Sbjct: 789 --AQVPPQMPPIPVVPPITPLAGIDGLPPA---LPDLPTATVP-PVPPPQYFSPAVILPS 842 Query: 841 PAMPLAPSHPS-PYQG------PRTQNISDYRAPGPQAIQPLPL----SPGVRPAS--SQ 887 A PL P+ P+ P Q P R P A +PL PGV S S Sbjct: 843 LAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSA 902 Query: 888 PQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMR--PGSTSLPETPRL--FPLLPLR 943 L GQ V P FP P P P MR P +LP P L P+LP + Sbjct: 903 VAQLPGQPVY---PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQ 959 Query: 944 PLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLP------------------------ 979 P P + V P P P P LP P P VLP Sbjct: 960 PTLPPQPV--LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAA 1017 Query: 980 TTG--ILTPHPGPQDSWKEA-----PAPRGNLQRNKLPETFMPPAP------------IT 1020 T G IL HP P A P P + LPE +P AP ++ Sbjct: 1018 TPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVS 1077 Query: 1021 APVMSLTPELQGIL-PSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLK 1079 A V S+ + +L P+ PP+ PG PG + P E E Q+ + Sbjct: 1078 ASVQSVPTQTATLLPPANPPL-------PGGPG-----IASPCPTVQLTVEPVQEEQASQ 1125 Query: 1080 SSFEALLQRC-SLSATDLKTKRKLEEAAQ 1107 L Q C S +D+ + ++L ++ + Sbjct: 1126 DKPPGLPQSCESYGGSDVTSGKELSDSCE 1154 Score = 50.4 bits (119), Expect = 1e-05 Identities = 74/258 (28%), Positives = 98/258 (37%), Gaps = 61/258 (23%) Query: 804 GATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPS--PYQGPRTQNI 861 G+T++S SS + S PSP V +P S L S PS YQ P Sbjct: 621 GSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA--- 677 Query: 862 SDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNP-VGFPGTWPLPGSPLPM--- 917 APG L G PA + P L + P+P + F P P +P+P Sbjct: 678 ----APG--------LPVGSVPAPACPPSL---QQHFPDPAMSFAPVLPPPSTPMPTGPG 722 Query: 918 --ACPGIMRP---GSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGA 972 A PG P T LP+ P++PL+P+ P H P PYL A Sbjct: 723 QPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPP-----HLP--------PYL-----A 764 Query: 973 PCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQG 1032 P S V G K P+ LQ MPP P+ P+ L + G Sbjct: 765 PASQV-----------GAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLA-GIDG 812 Query: 1033 ILPSQP--PVSSVSHAPP 1048 + P+ P P ++V PP Sbjct: 813 LPPALPDLPTATVPPVPP 830 Score = 41.6 bits (96), Expect = 0.005 Identities = 71/269 (26%), Positives = 95/269 (35%), Gaps = 39/269 (14%) Query: 832 PRVFTPQSSPAMPLA--PSHPSPYQGPRTQNISDYRAPG---------------PQAIQP 874 P P+SSP +PL+ P S P +S P P P Sbjct: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP 1381 Query: 875 LPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETP 934 PL+P P ++ PQ G P GT G P G+ TS P Sbjct: 1382 APLAPSSPPVTALPQ-DGAAPATSTMPEPASGTASQAGG--PGTPQGLTSELETSQPLAE 1438 Query: 935 RLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSW 994 L ++PL G + TPAP A+ D AP + P +PH G Sbjct: 1439 THEAPLAVQPLVVG-LAPCTPAPEAA-----STRDASAPREPLPPPAPEPSPHSGTPQPA 1492 Query: 995 KEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPP--VSSVSHAPPGVPG 1052 PAP LP + T+ + S P L +P QPP + S PP G Sbjct: 1493 LGQPAP-------LLPAAVGAVSLATSQLPS--PPLGPTVPPQPPSALESDGEGPPPRVG 1543 Query: 1053 ELSLQLQHLPPEKMERKELPPEHQSLKSS 1081 + ++ L EK+ R L EH S+ Sbjct: 1544 FVDSTIKSL-DEKL-RTLLYQEHVPTSSA 1570 Score = 40.0 bits (92), Expect = 0.013 Identities = 61/243 (25%), Positives = 82/243 (33%), Gaps = 33/243 (13%) Query: 899 PNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPR---LFPLLPLRPLGPGRMVSHTP 955 P P + PLP S LP P L + L L GP P Sbjct: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP 1381 Query: 956 AP--PASFPVPYLPGDPGAPCSSVLPT----TGILTPHPG-PQDSWKEAPAPRGNLQRNK 1008 AP P+S PV LP D AP +S +P T PG PQ E + + ++ Sbjct: 1382 APLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHE 1441 Query: 1009 LPETFMP---------PAPITAPVMSLTPELQGILPSQPPVSSVSHAP-----------P 1048 P P PAP A + + + P P S S P P Sbjct: 1442 APLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLP 1501 Query: 1049 GVPGELSLQLQHLPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQR 1108 G +SL LP + P +L+S E R + +K+ L+E + Sbjct: 1502 AAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKS---LDEKLRT 1558 Query: 1109 LEY 1111 L Y Sbjct: 1559 LLY 1561 Score = 32.3 bits (72), Expect = 2.7 Identities = 66/247 (26%), Positives = 85/247 (34%), Gaps = 45/247 (18%) Query: 827 TPSPRPRVFTPQSSPAMPLAP--SHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPA 884 TP+P S+P PL P PSP+ G P P QP PL P A Sbjct: 1457 TPAPEAASTRDASAPREPLPPPAPEPSPHSG----------TPQPALGQPAPLLPAAVGA 1506 Query: 885 SSQPQLLGGQRVQVPNPVGFPGTWPLPGSPL------PMACPGIMRPGSTSLPETPRLFP 938 S Q+P+P P P P S L P G + SL E R Sbjct: 1507 VSL------ATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560 Query: 939 LLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAP 998 P + F + L GD P S V L P P KEA Sbjct: 1561 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGD--QPRSEVCGGDLALPPVP------KEAV 1612 Query: 999 APRGNLQRNKLPETFMPPAPITAPVM------SLTPE-----LQGILPSQPPVSSVSHAP 1047 + R L + + ++ + AP VM S+T E + G V+S SH Sbjct: 1613 SGRVQLPQPLVEKSEL--APTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVV 1670 Query: 1048 PGVPGEL 1054 P VP ++ Sbjct: 1671 PSVPQDV 1677 Score = 31.6 bits (70), Expect = 4.7 Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 955 PAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKE-APAPRG 1002 PA PA + PG PGAP + G P P P + E APAP G Sbjct: 93 PAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDG 141 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 70.9 bits (172), Expect = 7e-12 Identities = 85/343 (24%), Positives = 119/343 (34%), Gaps = 35/343 (10%) Query: 731 PHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLP-RDCAQPPVQQLRDRLFHAQGSAVL 789 P G GP T + ++ + +++ + S P + +QPP L + G Sbjct: 770 PPGAESGPQTKF-CSEISLIVSPRRISVQLDSHQPTQSISQPPPPP---SLLWSAGQGQP 825 Query: 790 GQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSH 849 G Q P + + S + S +P+P P P + S P + + P Sbjct: 826 GSQPPHS------ISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP 879 Query: 850 PSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWP 909 P P G + P P +Q + P P L G + P P+ G P Sbjct: 880 PPPLPGMTVPTLPSTAIPQPPPLQGTEMLP------PPPPPLPGAGIPPPPPLPGAGILP 933 Query: 910 LPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASF--PVPYLP 967 LP P P PG+ P P +PL P PG + P P + P P LP Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993 Query: 968 GDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLT 1027 G G P LP GI P P P P G PP P+ + Sbjct: 994 G-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--------AGIPPPPPLPGAGIPPP 1044 Query: 1028 PELQGI-LPSQPPVSSVSHAPP------GVPGELSLQLQHLPP 1063 P L G +P PP+ PP G+P L +PP Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087 Score = 60.5 bits (145), Expect = 9e-09 Identities = 75/262 (28%), Positives = 92/262 (35%), Gaps = 32/262 (12%) Query: 821 PSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPG 880 P +P P P P P P P P G G PLP G Sbjct: 960 PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAG 1018 Query: 881 VRPASSQPQLLGGQRVQVPNPV---GFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLF 937 + P P L G + P P+ G P PLPG+ +P P PG+ P P Sbjct: 1019 IPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPG 1071 Query: 938 PLLPLRPLGPGRMVSHTPAPPASF--PVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWK 995 +P P PG + P P + P P LPG G P LP GI P P P Sbjct: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-VGIPPPPPLPGAGIPPPPPLPGAGIP 1130 Query: 996 EAP-------APRGNLQRNKLPETFMPPAPITAPVMSLTPELQGI-LPSQPPVSSVSHAP 1047 P P L R +P PP P+ + P L G +P PP+ V P Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIP----PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186 Query: 1048 P------GVPGELSLQLQHLPP 1063 P G+P L +PP Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPP 1208 Score = 55.5 bits (132), Expect = 3e-07 Identities = 74/241 (30%), Positives = 89/241 (36%), Gaps = 27/241 (11%) Query: 821 PSHQVPTPSPRPR--VFTPQSSPAMPLAPSHPSPYQG-PRTQNISDYRAPGPQ-----AI 872 P +P P P P + P P + P P P G P + P P I Sbjct: 1037 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096 Query: 873 QPLPLSPGVRPASSQPQLLGGQRVQVPNPV---GFPGTWPLPGSPLPMACPGIMRPGSTS 929 P P PGV P L G + P P+ G P PLPG+ +P P + R G Sbjct: 1097 PPPPPLPGV--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPRVGIPP 1153 Query: 930 LPETPRLFPLLPLRPLGPGRMVSHTPAPPASF--PVPYLPGDPGAPCSSVLPTTGILTPH 987 P P +P P PG + P P P P LPG G P LP GI P Sbjct: 1154 PPPLPGAG--IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG-VGIPPPPPLPGAGIPPPP 1210 Query: 988 PGPQDSWKEAPAP------RGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVS 1041 P P APAP G LP + P P TP++ G LP PP+ Sbjct: 1211 PLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLP--PPLP 1268 Query: 1042 S 1042 S Sbjct: 1269 S 1269 Score = 55.1 bits (131), Expect = 4e-07 Identities = 66/236 (27%), Positives = 80/236 (33%), Gaps = 22/236 (9%) Query: 821 PSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPG 880 P +P P P P P P P P G G PLP G Sbjct: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAG 1051 Query: 881 VRPASSQPQLLGGQRVQVPNPV---GFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLF 937 + P P L G + P P+ G P PLPG+ +P P PG+ P P Sbjct: 1052 IPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPG 1104 Query: 938 PLLPLRPLGPGRMVSHTPAPPASF--PVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWK 995 +P P PG + P P + P P LPG G P LP GI P P P Sbjct: 1105 VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPRVGIPPPPPLPGAGIP 1163 Query: 996 EAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVP 1051 P G PP P+ + P L G+ PP + PP P Sbjct: 1164 PPPPLPG--------AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 70.5 bits (171), Expect = 9e-12 Identities = 84/294 (28%), Positives = 109/294 (37%), Gaps = 41/294 (13%) Query: 792 QSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTP--QSSPAMPLAPSH 849 Q+PP P T ET S S P P P + +P Q P+ PL+P Sbjct: 570 QAPPSPL-------TTPPPETPS-------SIATPPPQAPPALASPPLQGLPSPPLSPLA 615 Query: 850 PSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVP------NPVG 903 P Q P + +AP P PLSP P+ P L +Q P PV Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASP-PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674 Query: 904 FPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPV 963 P + P P A P P S + P P P P P P S TP P A P+ Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAP--PLQVP--PSPPASPPMSPSATPPPQAPPPL 730 Query: 964 --PYLPGDPGAPCSSVLPTTGILTPHPGP---QDSWKEAPAPRGNLQRNKL--PETFMPP 1016 P L P P S + + P P + P+P +L + L P PP Sbjct: 731 AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790 Query: 1017 APITAPVMSLTP---ELQGILPSQP----PVSSVSHAPPGVPGELSLQLQHLPP 1063 A T P+ +L G P P P+S ++ PP P L+ L +PP Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844 Score = 64.3 bits (155), Expect = 6e-10 Identities = 96/360 (26%), Positives = 129/360 (35%), Gaps = 60/360 (16%) Query: 754 QGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETS 813 Q SL+ A+S L P+Q L H+ + + PP + +L + S Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529 Query: 814 SYRLGSQPSHQVPTPSPRP--RVFTPQSSPAMPLAP--------SHPSPYQGPRTQNISD 863 L + P +P+ +P P P ++P + P + PSP P + S Sbjct: 530 ---LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586 Query: 864 YRAPGPQAIQPL-----------PLSPGVRPASSQPQLLGGQRVQVP-----NPVGFPGT 907 P PQA L PLSP P P L +Q P +P P Sbjct: 587 IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646 Query: 908 WPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTP---APPASFPVP 964 P P +P +A + P S P P P P P P S TP APP S P Sbjct: 647 TPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSP--PASPPVSPSATPPSQAPP-SLAAP 702 Query: 965 YLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVM 1024 L P P S P + TP P +AP P P +PP+P +P M Sbjct: 703 PLQVPPSPPASP--PMSPSATPPP-------QAPPPLA------APPLQVPPSPPASPPM 747 Query: 1025 --SLTPELQGILPSQPPVSSVS--HAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKS 1080 S TP P PP+ + PP P L + PP + P Q+L S Sbjct: 748 SPSATPP-----PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802 Score = 58.2 bits (139), Expect = 5e-08 Identities = 74/278 (26%), Positives = 97/278 (34%), Gaps = 50/278 (17%) Query: 793 SPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVF------TPQSSPAMPLA 846 +P P P + + E R + PT PR V T + SPA Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227 Query: 847 PSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP--------QLLGGQRVQV 898 PS Q P ++++S P + P + G A + P Q L +V Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287 Query: 899 PNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPP 958 P P PL SPL P G+ + P P PL P P+PP Sbjct: 288 PRKDAAPALGPLSSSPLATPSPS----GTKARPVPPPDNAATPLPATLP-------PSPP 336 Query: 959 ASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAP 1018 + P+P P P AP S L P P PA P + PP+ Sbjct: 337 LATPLPLAPPSPSAPPS--------LQTLPSP-------PAT---------PPSQAPPS- 371 Query: 1019 ITAPVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSL 1056 +T P M P LQ I P Q P S S + P L+L Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409 Score = 57.8 bits (138), Expect = 6e-08 Identities = 80/271 (29%), Positives = 98/271 (36%), Gaps = 47/271 (17%) Query: 847 PSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPG 906 P PSP R+ RA G + P P +P RP G R V + Sbjct: 169 PGTPSPAMARRS------RAAGTEVGLPRP-APSARPRPPTE----GPRKSVSSASEHST 217 Query: 907 TWPLPGSPL-PMACPGIMRPGSTSLPE--TP-----------RLFPLLPLRPLGPGRMVS 952 T P P + P A G+ RP S SL TP R P P P P Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277 Query: 953 HTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPET 1012 PP P P AP L ++ + TP P K P P + LP T Sbjct: 278 QALRPPQVTP----PRKDAAPALGPLSSSPLATPSPS---GTKARPVPPPDNAATPLPAT 330 Query: 1013 FMP------PAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGV---PGELSLQLQHLPP 1063 P P P+ P S P LQ LPS PP + S APP + P + LQ +PP Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPSLQ-TLPS-PPATPPSQAPPSMTTPPMQAPPSLQTIPP 388 Query: 1064 EKMERKELPPEHQSLKSSFEALLQRCSLSAT 1094 ++ P Q+ S L SL AT Sbjct: 389 IQVPHSLTSPSLQAPPSP----LALSSLQAT 415 Score = 55.5 bits (132), Expect = 3e-07 Identities = 91/358 (25%), Positives = 118/358 (32%), Gaps = 85/358 (23%) Query: 792 QSPPFPFPRIVVGATL----------HSKETSSYRLG----SQPSHQVPTPSPRPRVFTP 837 Q+PP P + AT HS T S R + PS TP P + P Sbjct: 401 QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460 Query: 838 QSSPAMP-----LAPSHPSPYQGPRT----QNISDYRAPGPQAIQPLPLSPGVRPASSQP 888 S PA P L+P+ SP P T Q +S + PQA PLS + P Sbjct: 461 LSLPASPPLQTSLSPA-VSPLSSPLTIHPLQALSSLASHSPQA----PLSSLIMPPLETQ 515 Query: 889 QLLGGQRVQVP--------------------NPVGFPGTWP-LPGSPLPMACP--GIMRP 925 L +Q P P T P L P P CP P Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575 Query: 926 GSTSLPETPRLF--------------PL--LPLRPLGPGRMVSHTPAPPASFPVPYLPGD 969 +T PETP PL LP PL P + + P P +P L Sbjct: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP--LATPPPQAPPXLALPPLQAP 633 Query: 970 PGAPCSSVLPTTGILTPHPGPQDSWKE-------APAPRGNLQRNKLPETFMPPAPITAP 1022 P P S P + + TP P ++ +P P +Q P P +P P Sbjct: 634 PSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691 Query: 1023 VMSLTPELQG-------ILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPP 1073 P L P+ PP+S + PP P L+ +PP + P Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749 Score = 55.5 bits (132), Expect = 3e-07 Identities = 67/230 (29%), Positives = 86/230 (37%), Gaps = 55/230 (23%) Query: 819 SQPSHQVPTPS--PRPRVFTPQSSPAMPLAPSHP-SPYQGPRTQNISDYRAPGPQAIQPL 875 S P+ +PS P P+ P ++P + + PS P SP Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP----------------------- 745 Query: 876 PLSPGVRPASSQPQLLGGQRVQVP--NPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPET 933 P+SP P P LL +QVP P P + PL P P A P + P +LP Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS-PL-AKPPPQAPPALATPPLQALPSP 803 Query: 934 PRLFP-LLPLRPLGPGRMVSHTPAPPASFPV---PYLPGDPGAPCSSVL------PTTGI 983 P FP P P M PP + PV P L P P S L PT G Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863 Query: 984 LTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLT-PELQG 1032 T GP+ + AP P PP P +P +L+ P+L G Sbjct: 864 DTSVSGPRLTLALAPGP--------------PPPPSRSPSSTLSGPDLAG 899 Score = 37.7 bits (86), Expect = 0.065 Identities = 65/264 (24%), Positives = 86/264 (32%), Gaps = 51/264 (19%) Query: 765 PRDCAQPPVQQLRDRLFHAQGSAVLGQQS---------PPFPFPRIVVGATLHSKETSSY 815 P A PP+Q L G A + PP P ++ L + Sbjct: 789 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 848 Query: 816 RLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPL 875 Q + PTP P V P+ + + LAP P P + +S GP Sbjct: 849 SPTLQAPRRPPTPGPDTSVSGPRLT--LALAPGPPPPPSRSPSSTLS-----GPD----- 896 Query: 876 PLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPR 935 L+ A+S P+ L G P G P P + L P G P P Sbjct: 897 -LAGHSSSATSTPEELRGYD---SGPEGGAAASPPPDAELAACHPAAWSRG----PAPPL 948 Query: 936 LFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCS--------SVLPTTGILTPH 987 F P PL P PPA+ PG C+ S P G L P Sbjct: 949 AFRGAPGAPL---------PWPPATG-----PGSADGLCTIYETEGPESATPAPGALDPG 994 Query: 988 PGPQDSWKEAPAPRGNLQRNKLPE 1011 P P S +A A G ++ P+ Sbjct: 995 PSPGTSGGKAAAGAGAGASSRSPK 1018 Score = 32.3 bits (72), Expect = 2.7 Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 3/78 (3%) Query: 342 HMRQADKISSSFSKGQPLPPLQVPEQVAQAPLIPP-LKKPPKWIRRPT--GVSFAFGGKL 398 H QA +S S PL L +P Q+ L PP L+ PP + P + L Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546 Query: 399 VTFGLPSTPAHLVPQPCP 416 T P T HL PCP Sbjct: 547 QTASAPLTTPHLETPPCP 564 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 69.3 bits (168), Expect = 2e-11 Identities = 98/360 (27%), Positives = 130/360 (36%), Gaps = 54/360 (15%) Query: 733 GVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQ 792 G PATT+ T + A S T +S P+ PP + + + ++ Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLS--PKGVTLPPKETPTPSVVNLP----FPKE 898 Query: 793 SPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPR----PRVFTPQSSPAMPLAPS 848 P P P+ ++ S R P +PSP+ P TP S P PS Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958 Query: 849 -----------HPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQ-LLGGQRV 896 PSP GP T S AP P A P SP PA+ P+ V Sbjct: 959 PKWAPTPPAATPPSPKGGPATP--SPKGAPTPPA--ATPPSPKGGPATPSPKGAPTPPAV 1014 Query: 897 QVPNPVGFPGTWPLP-GSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPL-----GPGR- 949 P+P G P P P G+ P A GS + P+ P P L GP Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074 Query: 950 MVSHTPAPPASFPV-----PYLPGDPGAP----CSSVLPTTGILT-PHPG-PQDSWKEAP 998 + P PPA+ P P P GAP + P G+ T PH G P P Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134 Query: 999 APRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPP---VSSVSHAPPGVPGELS 1055 +P+G L P P P P P +G L + PP ++ + PP G L+ Sbjct: 1135 SPKGGLATP--PPKGAPTTPAATP-----PSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187 Score = 65.1 bits (157), Expect = 4e-10 Identities = 70/267 (26%), Positives = 96/267 (35%), Gaps = 45/267 (16%) Query: 821 PSHQVPTPSPRPRVFTPQSSPAMPLAP-SHPSPYQGPRTQNISDYRAPGPQAIQPLPLSP 879 P + TPSP+ TP ++P P + PSP P T + G A P P Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP-PKGA 1263 Query: 880 GVRPASSQPQLLGGQR------------VQVPNPVGFPGTWPLPGSPLPMACPGIMRPGS 927 PA++ P L GG V P+P G P T P G+P P P P Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP---PAATPPSP 1320 Query: 928 TSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPH 987 P TP P G P PPA P P G P P ++ G TP Sbjct: 1321 KGSPGTP--------PPKG-------APTPPAVTP-PSPKGTPTLPATTPSSKGGPTTP- 1363 Query: 988 PGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVM------SLTPELQGILPSQPPVS 1041 S KE P P +K PP+P P + +P + + P + P + Sbjct: 1364 -----SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418 Query: 1042 SVSHAPPGVPGELSLQLQHLPPEKMER 1068 V+ P + L + P +++ Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKK 1445 Score = 64.7 bits (156), Expect = 5e-10 Identities = 67/232 (28%), Positives = 91/232 (39%), Gaps = 21/232 (9%) Query: 821 PSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPG 880 P + TP P+ TP ++P P P +G T + +P P P Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195 Query: 881 VRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLL 940 PA++ P GG + P+P G P T P + P G+ P P TP P Sbjct: 1196 TTPAATPPSPKGG--LATPSPKGAPTT---PAATPPSPKGGLATPSPKGAPTTPAATP-- 1248 Query: 941 PLRPLGPGR-MVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPA 999 P GP P PPA+ P P L G P P ++TP P P+ +P Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATP-PSLKGGLATPPHKGAPNPAVVTP-PSPKGGPATSP- 1305 Query: 1000 PRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVP 1051 P+G P PP+P +P TP +G P+ P V+ S P G P Sbjct: 1306 PKG----APTPPAATPPSPKGSPG---TPPPKG-APTPPAVTPPS--PKGTP 1347 Score = 59.7 bits (143), Expect = 2e-08 Identities = 60/232 (25%), Positives = 83/232 (35%), Gaps = 34/232 (14%) Query: 827 TPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASS 886 TPSP+ P ++P P P++G T + +P P P PA++ Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155 Query: 887 QPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLG 946 P GG + P P G P T P + P G+ P P TP P Sbjct: 1156 PPSPKGG--LATPPPKGAPTT---PAATPPSPKGGLATPSPKGAPTTPAATP-------- 1202 Query: 947 PGRMVSHTPAPPASFPVPYLPGDPGAPCSS-VLPTTGILTPHP--GPQDSWKEAPAPRGN 1003 P+P P G P P ++ P G+ TP P P P+P+G Sbjct: 1203 --------PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254 Query: 1004 LQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHA---PPGVPG 1052 P T PP P + P L+G L + P + + A PP G Sbjct: 1255 ------PAT-PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299 Score = 59.3 bits (142), Expect = 2e-08 Identities = 68/275 (24%), Positives = 90/275 (32%), Gaps = 54/275 (19%) Query: 821 PSHQVPTPSPRPRVFTPQSSPAMPLAPS-----------HPSPYQGPRTQNISDYRAP-- 867 P+ P +P P TP S P PS PSP GP T + P Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013 Query: 868 -------GPQAIQPLPLSPGVRPASSQPQLLGG-------------QRVQVPNPVGFPGT 907 G A P P PA++ P G +P+P G P T Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073 Query: 908 WPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLP 967 L G+P P A + P +P+ P P P + P+P P Sbjct: 1074 PSLKGAPTPPA----------ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123 Query: 968 GDPGAPCSS-VLPTTGILTPHP--GPQDSWKEAPAPRGNLQR---NKLPET--FMPPAP- 1018 G P P ++ P G+ TP P P P+P+G L P T PP+P Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183 Query: 1019 --ITAPVMSLTPELQGILPSQPPVSSVSHAPPGVP 1051 + P P P P + +P G P Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218 Score = 57.8 bits (138), Expect = 6e-08 Identities = 77/308 (25%), Positives = 115/308 (37%), Gaps = 61/308 (19%) Query: 790 GQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQ------VPTPSPRPRVFTPQSSPAM 843 G + P P G T S + + PSH+ P+P P + +P+ P Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404 Query: 844 PL--------APSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQR 895 P AP+ P +G T + D P A+ P+ L PA+S P+ GG Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSKGDLTPP---AVTPVSLKKA--PATSAPK--GGPA 1457 Query: 896 VQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTP 955 P+ G P T P P P P P + +P+ P P P+G + + P Sbjct: 1458 T--PSSKGDP-TLPAVTPPSPKEPPA---PKQVATSSSPKKAPATPA-PMGAPTLPAVIP 1510 Query: 956 APPASFPV-PYLPGDPGAPCSSVL---------PTTGILTPH---PGPQDSW-----KEA 997 + P P P DP AP +++L P ++ P P P+ + KEA Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570 Query: 998 PAPRGNLQRNKLP--------------ETFMPPAPITAPVMSLTPELQGILPSQPPVSSV 1043 PA + + + P E +PPA +T+P P + P P Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPA-VTSPSPKEAPTPPAVTPPSPEKGPA 1629 Query: 1044 SHAPPGVP 1051 + AP G P Sbjct: 1630 TPAPKGTP 1637 Score = 56.6 bits (135), Expect = 1e-07 Identities = 71/280 (25%), Positives = 103/280 (36%), Gaps = 42/280 (15%) Query: 790 GQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSH 849 G +P P G TL KET + + + +P P P P+ +PA+ + S Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVN-----LPFPKEGPATPAPKQAPALSMTSSS 917 Query: 850 PSPYQG-PRTQNI----SDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVP-NPVG 903 P + P + I S AP P A P SP PA+ P+ P +P G Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPP--SPKGGPATPSPKWAPTPPAATPPSPKG 975 Query: 904 FPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPV 963 P T G+P P A + P +P+ P P P G P PPA P Sbjct: 976 GPATPSPKGAPTPPA----------ATPPSPKGGPATP-SPKG-------APTPPAVTP- 1016 Query: 964 PYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPV 1023 P G+P ++ P P P P+P+G+ LP+ T P Sbjct: 1017 ---PSPKGSPAATPFPKGASTPPAATP-------PSPKGSPAATPLPKGAPTTPAATLPS 1066 Query: 1024 MSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPP 1063 P + + P ++ +P G P S + +PP Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106 Score = 53.9 bits (128), Expect = 9e-07 Identities = 65/275 (23%), Positives = 98/275 (35%), Gaps = 56/275 (20%) Query: 818 GSQPSHQVPTP------SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQA 871 G+ P PTP SP+ P ++P+ P+ PS +GP + GP Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384 Query: 872 IQP--------------------LPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPL- 910 P +PLSP PA+ P G + P P+ Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT--PVTREGAATPSKGDLTPPAVTPVS 1442 Query: 911 ----PGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHT-----PAPPASF 961 P + P P P S P P + P P P P ++ + + PA PA Sbjct: 1443 LKKAPATSAPKGGPA--TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500 Query: 962 PVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITA 1021 P LP +V+P++ P S ++ AP L K P T P + Sbjct: 1501 GAPTLP--------AVIPSSP--KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550 Query: 1022 PVMSL-TPELQGILPS-----QPPVSSVSHAPPGV 1050 P M++ +P+ +P+ P S + +PP V Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585 Score = 53.5 bits (127), Expect = 1e-06 Identities = 84/325 (25%), Positives = 123/325 (37%), Gaps = 73/325 (22%) Query: 805 ATLHSKETSSYRLGSQ----PSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSP-------Y 853 ATL SK+T + + P+ VP+P P + TP+ +PA P + SP Y Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590 Query: 854 QG----------PRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVG 903 +G P + S AP P A+ P SP PA+ P+ P+ + Sbjct: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP--SPEKGPATPAPKGTPTSPPVTPSSLK 1648 Query: 904 FPGTWPLP-----GSPLPMACPGI-MRPGSTSLPET-----PRLFPLL--PLRPLGPGRM 950 T P G+ +P A G+ + G T+L E P P++ P R GP Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK-GPQTK 1707 Query: 951 VSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAP------APRGNL 1004 S +PP P P P S+V P + P +DS K A +P+G L Sbjct: 1708 KSSATSPPIC-PDPSAKNGSKGPLSTVAPAPLL----PVQKDSSKTAKGKDASHSPKGPL 1762 Query: 1005 Q---------------RNKLPE------TFMPPAPITAPV----MSLTPELQGILPSQPP 1039 LP+ + P P++ P+ + P Q LPS P Sbjct: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPG 1822 Query: 1040 VSSVSHAPPGVPGELSLQLQHLPPE 1064 + S + P P + L +PPE Sbjct: 1823 LVLESPSKPLAPADEDELLPLIPPE 1847 Score = 39.7 bits (91), Expect = 0.017 Identities = 69/278 (24%), Positives = 98/278 (35%), Gaps = 58/278 (20%) Query: 838 QSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQ 897 Q P +P P P+P Q P + P P I PL +SS L G + Sbjct: 40 QPGPTLP-PPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPE 98 Query: 898 ----VPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSH 953 +PN +G P + PM P + S+S P L L L P + Sbjct: 99 APTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAP--------LALVALAPHSVQKS 150 Query: 954 TPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETF 1013 + PP P P A SV+ + + P P+ NL NK+P Sbjct: 151 SAFPPNLLTSP--PSVAVAESGSVITLSAPIAP-----------SEPKTNL--NKVPSEV 195 Query: 1014 MP-----PAP----ITAPVMSLTPELQ-----GILPSQPPVSSVSHAPPGV--------- 1050 +P P+P T P +TP LP P ++++ A P V Sbjct: 196 VPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVL 255 Query: 1051 -----PGELSLQLQHLPPE--KMERKELPPEHQSLKSS 1081 PG LSL+ PP + + LP S K++ Sbjct: 256 ISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTA 293 Score = 36.2 bits (82), Expect = 0.19 Identities = 101/405 (24%), Positives = 140/405 (34%), Gaps = 69/405 (17%) Query: 707 SPMALQDLMEKVMVL--NRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFL 764 SP + V++ N L+GP VSP PA TQ +L S TA Sbjct: 243 SPQVKDTTISSVLISPQNPGSLSLKGP--VSP-PAALSLSTQ--SLPVVTSSQKTAGPNT 297 Query: 765 PRDCAQPPVQQLRDRLFHAQGSA-VLGQQSPP-FPFPRIVVGATLHSKETSSYRLGSQPS 822 P D L + GS +LGQ P P + + HS +SY SQ S Sbjct: 298 PPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYP--SQRS 355 Query: 823 HQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRT-QNISDYRAPGPQAIQPLPLSPGV 881 P PS V P + A P+ PS +GP T +I+ + LSP Sbjct: 356 VIPPLPSRNEVV--PATVAAFPVVA--PSVDKGPSTISSITCSPSGSLNVATSFSLSPTT 411 Query: 882 RPA-SSQPQLLGGQRVQVPNPVGFPGTWPL-----------PGSPLPMAC----PGIMRP 925 S P + PV GT PL P + +A P P Sbjct: 412 SLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGP 471 Query: 926 GSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVP--------------------- 964 S P +P + P+ P P V+ T P S P+P Sbjct: 472 ISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKD 531 Query: 965 ------YLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLP-------- 1010 L G P +P + L T T P Q + K +P+ + ++P Sbjct: 532 LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLA 591 Query: 1011 -ETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVPGEL 1054 ++ P PI P S+T L G+ S + + S+A P G L Sbjct: 592 KKSLGEPLPIGKPASSMTSPL-GVNSSASVIKTDSYAGPDSAGPL 635 Score = 34.7 bits (78), Expect = 0.55 Identities = 52/226 (23%), Positives = 75/226 (33%), Gaps = 26/226 (11%) Query: 784 QGSAVLGQQSPPFPFPRIVVGATLHSKE--TSSYRLGSQP---SHQVPTPSPRPRVFTPQ 838 Q S L + P ++V S T+ R G Q S P P P Sbjct: 1667 QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS 1726 Query: 839 SSPAMPLAPSHPSPYQGPRTQNI----SDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQ 894 P +AP+ P Q ++ + + GP A S + A+ + L + Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE 1786 Query: 895 RVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHT 954 V P + PL SP+P + P LP +P L P +PL P Sbjct: 1787 SASVSAAPSPPVSLPLAPSPVPT-----LPPKQQFLPSSPGLVLESPSKPLAPADEDE-- 1839 Query: 955 PAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAP 1000 LP P P S +P +L P P+ + P P Sbjct: 1840 ----------LLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTP 1875 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 67.4 bits (163), Expect = 8e-11 Identities = 85/302 (28%), Positives = 106/302 (35%), Gaps = 60/302 (19%) Query: 794 PPFPFPR-IVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVF----TPQSSPAM----- 843 PP PR V A+ HS S +PS P R TP SSPA Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 Query: 844 ---PLAPSHPSP-----YQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQR 895 P AP+HPS Q R ++ R A+ PL SP P+ S P Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP------- 303 Query: 896 VQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTP 955 P+P P LP P GS +L T P PL PL TP Sbjct: 304 ---PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-------TP 353 Query: 956 AP--PASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETF 1013 P P + +P L P P S P + + TP P +AP L + L F Sbjct: 354 PPQAPPALALPPLQAPPSPPASP--PLSPLATPSP-------QAP---NALAVHLLQAPF 401 Query: 1014 MPPA--PITAPVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKEL 1071 PP P+ AP P+ PPVS + P P L+ +PP + Sbjct: 402 SPPPSPPVQAPFSP---------PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452 Query: 1072 PP 1073 P Sbjct: 453 SP 454 Score = 64.7 bits (156), Expect = 5e-10 Identities = 82/286 (28%), Positives = 106/286 (37%), Gaps = 51/286 (17%) Query: 819 SQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQA---IQPL 875 SQP + P+V P+ A L P SP P S P P A +Q L Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP-----SPSAPPSPSAPPSLQTL 315 Query: 876 PLSPGVRPASSQPQLLGGQRVQ-----VPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSL 930 P SP P S LG +Q +P+P P P P +P +A P + P S Sbjct: 316 P-SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-- 372 Query: 931 PETPRLFPLLPLRPLGPGRMVSH----------TP------APPASFPVPYLPGDPG-AP 973 P +P L PL P P + H +P +PPAS PV P AP Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432 Query: 974 CSSVLPTTGIL-TPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQG 1032 S P + +P P S P P+ P P P P ++ TP LQ Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA-TPPLQA 491 Query: 1033 ILPSQP---------------PVSSVSHAPPGVPGELSLQLQHLPP 1063 LPS P P+S ++ PP P L+ L +PP Sbjct: 492 -LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 536 Score = 62.4 bits (150), Expect = 2e-09 Identities = 86/321 (26%), Positives = 119/321 (37%), Gaps = 52/321 (16%) Query: 724 SLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHA 783 SL+ L P P ATT +L SFLP PP+ L A Sbjct: 311 SLQTLPSPPATPPSQATTS---------LGSPTLQATHSFLP----SPPLSPLATPPPQA 357 Query: 784 QGSAVLGQ-QSPPFP--FPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRV-FTPQS 839 + L Q+PP P P + AT + ++ + + P PSP + F+P + Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 Query: 840 SPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVP 899 SP P++PS P Q P + + P P P+SP P P L +Q+ Sbjct: 418 SP--PVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLA 474 Query: 900 NP-------VGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVS 952 P + P LP P P S SLP +P P P+ ++ Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSP-SASLPMSPLATPPPQAPPVLAAPLLQ 533 Query: 953 HTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPET 1012 P+PPAS P P P PT G T GP+ + AP P Sbjct: 534 VPPSPPAS-PTLQAPRRP--------PTPGPDTSVSGPRLTLALAPGP------------ 572 Query: 1013 FMPPAPITAPVMSLT-PELQG 1032 PP P +P +L+ P+L G Sbjct: 573 --PPPPSRSPSSTLSGPDLAG 591 Score = 50.1 bits (118), Expect = 1e-05 Identities = 72/241 (29%), Positives = 86/241 (35%), Gaps = 34/241 (14%) Query: 847 PSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPG 906 P PSP R+ RA G + P P +P RP G R V + Sbjct: 160 PGTPSPAMARRS------RAAGTEVGLPRP-APSARPRPPTE----GPRKSVSSASEHST 208 Query: 907 TWPLPGSPL-PMACPGIMRPGSTSLPETPRLFPLLPLR-PLGPGRMVSHTPAPPA--SFP 962 T P P + P A G+ RP S SL + PL P G TP PA S P Sbjct: 209 TEPSPAARRRPSAGGGLQRPASRSLSSSAT-----PLSSPARSGPSARGTPRAPAHPSQP 263 Query: 963 VP-----YLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPA 1017 P P P P G L+ P S P+P LP PPA Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS---PPA 320 Query: 1018 --PITAPVMSLTPELQG---ILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELP 1072 P A +P LQ LPS PP+S ++ PP P L+L PP L Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPS-PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379 Query: 1073 P 1073 P Sbjct: 380 P 380 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 65.9 bits (159), Expect = 2e-10 Identities = 105/363 (28%), Positives = 134/363 (36%), Gaps = 49/363 (13%) Query: 721 LNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQG--SLATAMSFLPRDCAQPPVQQLRD 778 L+ S L P P T R + + +G +L PR A P + L Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301 Query: 779 R-LFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTP 837 L SA L Q+PP + AT HS + +L + P+PS P + T Sbjct: 302 SPLATPSPSAALQSQAPP------TLPATPHSSSLTC-QLATPLPLAPPSPSAPPSLQTL 354 Query: 838 QSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQ 897 S PA P PS + G T + P P PLSP P P L +Q Sbjct: 355 PSPPATP--PSQATTSLGSPTLQATHSFLPSP------PLSPLATPPPQAPPALALPPLQ 406 Query: 898 VP-----NPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVS 952 P +P P P P +P +A + P S P P P P P P S Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSP--PASPPVSPS 463 Query: 953 HTP---APPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGN--LQRN 1007 TP APP S P L P P S P + TP P +AP P LQ Sbjct: 464 ATPPSQAPP-SLAAPPLQVPPSPPASP--PMSPSATPPP-------QAPPPLAAPPLQLA 513 Query: 1008 KLPETFMPPAPITAPVMSLTP---ELQGILPSQP----PVSSVSHAPPGVPGELSLQLQH 1060 K P PPA T P+ +L G P P P+S ++ PP P L+ L Sbjct: 514 KPPPQ-APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572 Query: 1061 LPP 1063 +PP Sbjct: 573 VPP 575 Score = 62.4 bits (150), Expect = 2e-09 Identities = 86/321 (26%), Positives = 119/321 (37%), Gaps = 52/321 (16%) Query: 724 SLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHA 783 SL+ L P P ATT +L SFLP PP+ L A Sbjct: 350 SLQTLPSPPATPPSQATTS---------LGSPTLQATHSFLP----SPPLSPLATPPPQA 396 Query: 784 QGSAVLGQ-QSPPFP--FPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRV-FTPQS 839 + L Q+PP P P + AT + ++ + + P PSP + F+P + Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456 Query: 840 SPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVP 899 SP P++PS P Q P + + P P P+SP P P L +Q+ Sbjct: 457 SP--PVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLA 513 Query: 900 NP-------VGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVS 952 P + P LP P P S SLP +P P P+ ++ Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPFSP-SASLPMSPLATPPPQAPPVLAAPLLQ 572 Query: 953 HTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPET 1012 P+PPAS P P P PT G T GP+ + AP P Sbjct: 573 VPPSPPAS-PTLQAPRRP--------PTPGPDTSVSGPRLTLALAPGP------------ 611 Query: 1013 FMPPAPITAPVMSLT-PELQG 1032 PP P +P +L+ P+L G Sbjct: 612 --PPPPSRSPSSTLSGPDLAG 630 Score = 59.7 bits (143), Expect = 2e-08 Identities = 86/322 (26%), Positives = 108/322 (33%), Gaps = 70/322 (21%) Query: 794 PPFPFPR-IVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVF----TPQSSPAM----- 843 PP PR V A+ HS S +PS P R TP SSPA Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259 Query: 844 ---PLAPSHPSP-----YQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP------- 888 P AP+HPS Q R ++ R A+ PL SP P+ S Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP 319 Query: 889 -------------QLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPR 935 QL + P+P P LP P GS +L T Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379 Query: 936 LFPLLPLRPLGPGRMVSHTPAP--PASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDS 993 P PL PL TP P P + +P L P P S P + + TP P Sbjct: 380 FLPSPPLSPLA-------TPPPQAPPALALPPLQAPPSPPASP--PLSPLATPSP----- 425 Query: 994 WKEAPAPRGNLQRNKLPETFMPPA--PITAPVMSLTPELQGILPSQPPVSSVSHAPPGVP 1051 +AP L + L F PP P+ AP P+ PPVS + P P Sbjct: 426 --QAP---NALAVHLLQAPFSPPPSPPVQAPFSP---------PASPPVSPSATPPSQAP 471 Query: 1052 GELSLQLQHLPPEKMERKELPP 1073 L+ +PP + P Sbjct: 472 PSLAAPPLQVPPSPPASPPMSP 493 Score = 52.4 bits (124), Expect = 3e-06 Identities = 69/287 (24%), Positives = 102/287 (35%), Gaps = 29/287 (10%) Query: 804 GATLHSKETSSYRLGSQPSHQVPTP-SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNIS 862 G + + S+ G++ PTP +P P + + + P+P PR Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT-- 202 Query: 863 DYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGI 922 GP+ +S ++++P +R + P + L S P++ P Sbjct: 203 ----EGPRK----SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254 Query: 923 MRPGSTSLPETPRLFPLLP----LRPLGPGRMVS-HTPAPPASFPV---PYLPGDPGAPC 974 P + P P P P L+ L P ++ A PA P+ P P A Sbjct: 255 SGPSARGTPRAPA-HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAAL 313 Query: 975 SSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPET-FMPPAPITAPVMSLT----PE 1029 S P T TPH P P + P +P P T P + T P Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373 Query: 1030 LQG---ILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPP 1073 LQ LPS PP+S ++ PP P L+L PP L P Sbjct: 374 LQATHSFLPS-PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 419 >gi|41281612 zinc finger protein 828 [Homo sapiens] Length = 812 Score = 65.1 bits (157), Expect = 4e-10 Identities = 74/289 (25%), Positives = 104/289 (35%), Gaps = 33/289 (11%) Query: 785 GSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMP 844 GS V + P P P A++ S E + P PSP P+ P S ++ Sbjct: 160 GSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVK 219 Query: 845 LAPSHPSPYQG---PRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNP 901 S+P P + P T +P + P G PA+S P+ R P P Sbjct: 220 ATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAAS-PESRKSARTTSPEP 278 Query: 902 ------------VGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGR 949 FP P P P P PG +PG P +PR + P GP + Sbjct: 279 RKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGP---PGSPRPWKSNPSASSGPWK 335 Query: 950 MVSHTP--APPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRN 1007 P +P P+P + P P SV ++ SWK PA + + Sbjct: 336 PAKPAPSVSPGPWKPIPSVSPGPWKPTPSV--SSASWKSSSVSPSSWKSPPASPESWKSG 393 Query: 1008 KLPETFMPPAPITAP-----VMSLTPELQGILPSQPPVSSVSHAPPGVP 1051 P AP +P V ++PEL+ PP+S +P G P Sbjct: 394 --PPELRKTAPTLSPEHWKAVPPVSPELR---KPGPPLSPEIRSPAGSP 437 Score = 51.6 bits (122), Expect = 4e-06 Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 16/134 (11%) Query: 926 GSTSLPETPRLFPLLPLRPLGPGRMVS---HTPAPPASFPVPYLPGDPGAPCSSVLPTTG 982 GS PE+P+ PL PL P PG +VS TP P P P P S + + Sbjct: 138 GSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQ 197 Query: 983 ILTPHPGPQDSWKEAPAPRGNL----------QRNKLPETFMPPAPIT--APVMSLTPEL 1030 L P P P+ K AP ++ +++ PET PP+ + +PV++ +PE Sbjct: 198 KLAPVPSPEPQ-KPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEP 256 Query: 1031 QGILPSQPPVSSVS 1044 G P+ P S S Sbjct: 257 WGPSPAASPESRKS 270 >gi|58331266 WD repeat domain 59 [Homo sapiens] Length = 974 Score = 65.1 bits (157), Expect = 4e-10 Identities = 41/140 (29%), Positives = 72/140 (51%), Gaps = 11/140 (7%) Query: 118 QKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWN 177 Q HT + LD F+ +LL + + D+ I+IWD+ + P T+ + +K WN Sbjct: 102 QGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKP-TVALSAVAGASQVK---WN 157 Query: 178 RQAQHILSSAHPSGKAVVWDLRKNEPIIK-VSDHSNRMHCSGLAWHPDIATQLVLCSEDD 236 ++ + L+++H G +WD RK ++ ++ H +++H GL WHPD L S+D+ Sbjct: 158 KKNANCLATSH-DGDVRIWDKRKPSTAVEYLAAHLSKIH--GLDWHPDSEHILATSSQDN 214 Query: 237 RLPVIQLWDLRFASSPLKVL 256 ++ WD R L +L Sbjct: 215 S---VKFWDYRQPRKYLNIL 231 Score = 40.0 bits (92), Expect = 0.013 Identities = 37/178 (20%), Positives = 73/178 (41%), Gaps = 12/178 (6%) Query: 109 GKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPP 168 G + Q + GAV+ + F AS +++ W + V TL ++ Sbjct: 50 GHRKISRQSKWDIGAVQWNPHDSFAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRV-- 107 Query: 169 EDIKALSWNRQAQHILSSAHPSGKAVVWDLRKN-EPIIKVSDHSNRMHCSGLAWHPDIAT 227 I L W +L ++ +WD++ +P + +S + S + W+ A Sbjct: 108 --ISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAG---ASQVKWNKKNAN 162 Query: 228 QLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQI 285 L + D +++WD R S+ ++ L +H I + W +L TS++D+ + Sbjct: 163 CLATSHDGD----VRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSV 216 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 62.8 bits (151), Expect = 2e-09 Identities = 93/360 (25%), Positives = 124/360 (34%), Gaps = 72/360 (20%) Query: 728 LRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSA 787 L+ P GV+P P++ T L G +A + P+ P Q ++ Sbjct: 187 LQAPTGVTPAPSSAPPGTPQ---LPTPGPTPSATAVPPQ--GSPTASQAPNQ-------- 233 Query: 788 VLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPS-HQVPTPSPRPRVFTPQSSPAMPLA 846 Q+P P P H ++ + PS H P PSP P + S P A Sbjct: 234 ---PQAPTAPVPHT------HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284 Query: 847 PSHPSP---YQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVG 903 PSH P QGP PGP ++Q PL P QP L Q Q P+G Sbjct: 285 PSHAQPPLHGQGP----------PGPHSLQAGPLLQ--HPGPPQPFGLPPQASQGQAPLG 332 Query: 904 FPGTWPLPGSPLPM-----ACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPP 958 P + L + A P LP P P + P P + PAP Sbjct: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQ 389 Query: 959 ASFPVPYLPGDPGAPCSSVLPTTGILTP------------HPGPQDSWKEA-PAPRGNLQ 1005 A P+L G ++ LP L P HP P ++ P P Q Sbjct: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 449 Query: 1006 RNKLPET-FMPPAPITAPVMSL------TPELQ------GILPSQPPVSSVSHAPPGVPG 1052 L ++ +PP P + P L P Q G P PP + PP PG Sbjct: 450 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 509 Score = 58.9 bits (141), Expect = 3e-08 Identities = 81/284 (28%), Positives = 102/284 (35%), Gaps = 69/284 (24%) Query: 824 QVPTPSPRPRVFT--PQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQA-IQPLPLSPG 880 Q+PTP P P PQ SP AP+ P Q P AP P IQ P Sbjct: 206 QLPTPGPTPSATAVPPQGSPTASQAPNQP---QAPT--------APVPHTHIQQAPALHP 254 Query: 881 VRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLL 940 RP S P P+P P PL GS + P +P PL Sbjct: 255 QRPPSPHPP---------PHPSPHPPLQPLTGSAGQPSAPSHAQP------------PLH 293 Query: 941 PLRPLGP-----GRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWK 995 P GP G ++ H P PP F +P AP + + PH Q Sbjct: 294 GQGPPGPHSLQAGPLLQH-PGPPQPFGLPPQASQGQAPLGT---SPAAAYPHTSLQ---- 345 Query: 996 EAPAPRGNLQRNKLP-ETFMPPAPI---------TAPVMSLT--------PELQGILPSQ 1037 PA + LQ + P E +PPAP+ T P+ L P L G PS Sbjct: 346 -LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG--PSP 402 Query: 1038 PPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKSS 1081 +++ PP + SL H P +L P+ Q L SS Sbjct: 403 FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS 446 Score = 56.6 bits (135), Expect = 1e-07 Identities = 88/327 (26%), Positives = 111/327 (33%), Gaps = 79/327 (24%) Query: 793 SPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPR-PRVFTPQSSPAMPLAPSHPS 851 SP P P+ E+ S Q Q P+ + P TP S A P P P+ Sbjct: 158 SPSIPSPQ--------DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 209 Query: 852 PYQGPRTQNISDYRAP-------GPQA---------IQPLPLSPGVRPASSQPQLLGGQR 895 P P + +P PQA IQ P RP S P Sbjct: 210 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP------ 263 Query: 896 VQVPNPVGFPGTWPLPGSPLPMACP--------GIMRPGSTSLPETPRLFPLLPLRPLGP 947 P+P P PL GS + P G PG SL P L P +P G Sbjct: 264 ---PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 320 Query: 948 GRMVSHTPAPPASFPVP-------YLPGDPGA------PCSSVLPTTGILTPH--PGPQD 992 S AP + P LP A P LP + PH P P Sbjct: 321 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 380 Query: 993 SWKEAPAPRGNLQRNKL--PETF-----MPPAPITAPVMSLT---------PELQGILPS 1036 + PAP+ + L P F +PP P P+ SL+ P LQ ++P Sbjct: 381 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQ 439 Query: 1037 QPPVSSVSHAPPGVPGELSLQLQHLPP 1063 P+ S PPG+ Q Q+LPP Sbjct: 440 SQPLPSSPAQPPGL-----TQSQNLPP 461 Score = 50.1 bits (118), Expect = 1e-05 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 13/132 (9%) Query: 954 TPAPPASFP-VPYLPGDPGAPCSSVLPTTGILTPHPGP-QDSWKEAPAPRGNLQRNKLPE 1011 TPAP ++ P P LP P ++ +P G T P Q AP P ++Q+ Sbjct: 194 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 253 Query: 1012 TFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPP-----GVPGELSLQ----LQHLP 1062 PP+P P S P LQ + S S+ SHA P G PG SLQ LQH Sbjct: 254 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH-- 311 Query: 1063 PEKMERKELPPE 1074 P + LPP+ Sbjct: 312 PGPPQPFGLPPQ 323 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 62.8 bits (151), Expect = 2e-09 Identities = 93/360 (25%), Positives = 124/360 (34%), Gaps = 72/360 (20%) Query: 728 LRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSA 787 L+ P GV+P P++ T L G +A + P+ P Q ++ Sbjct: 741 LQAPTGVTPAPSSAPPGTPQ---LPTPGPTPSATAVPPQ--GSPTASQAPNQ-------- 787 Query: 788 VLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPS-HQVPTPSPRPRVFTPQSSPAMPLA 846 Q+P P P H ++ + PS H P PSP P + S P A Sbjct: 788 ---PQAPTAPVPHT------HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838 Query: 847 PSHPSP---YQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVG 903 PSH P QGP PGP ++Q PL P QP L Q Q P+G Sbjct: 839 PSHAQPPLHGQGP----------PGPHSLQAGPLLQ--HPGPPQPFGLPPQASQGQAPLG 886 Query: 904 FPGTWPLPGSPLPM-----ACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPP 958 P + L + A P LP P P + P P + PAP Sbjct: 887 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQ 943 Query: 959 ASFPVPYLPGDPGAPCSSVLPTTGILTP------------HPGPQDSWKEA-PAPRGNLQ 1005 A P+L G ++ LP L P HP P ++ P P Q Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003 Query: 1006 RNKLPET-FMPPAPITAPVMSL------TPELQ------GILPSQPPVSSVSHAPPGVPG 1052 L ++ +PP P + P L P Q G P PP + PP PG Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063 Score = 58.9 bits (141), Expect = 3e-08 Identities = 81/284 (28%), Positives = 102/284 (35%), Gaps = 69/284 (24%) Query: 824 QVPTPSPRPRVFT--PQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQA-IQPLPLSPG 880 Q+PTP P P PQ SP AP+ P Q P AP P IQ P Sbjct: 760 QLPTPGPTPSATAVPPQGSPTASQAPNQP---QAPT--------APVPHTHIQQAPALHP 808 Query: 881 VRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLL 940 RP S P P+P P PL GS + P +P PL Sbjct: 809 QRPPSPHPP---------PHPSPHPPLQPLTGSAGQPSAPSHAQP------------PLH 847 Query: 941 PLRPLGP-----GRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWK 995 P GP G ++ H P PP F +P AP + + PH Q Sbjct: 848 GQGPPGPHSLQAGPLLQH-PGPPQPFGLPPQASQGQAPLGT---SPAAAYPHTSLQ---- 899 Query: 996 EAPAPRGNLQRNKLP-ETFMPPAPI---------TAPVMSLT--------PELQGILPSQ 1037 PA + LQ + P E +PPAP+ T P+ L P L G PS Sbjct: 900 -LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG--PSP 956 Query: 1038 PPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKSS 1081 +++ PP + SL H P +L P+ Q L SS Sbjct: 957 FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS 1000 Score = 56.6 bits (135), Expect = 1e-07 Identities = 88/327 (26%), Positives = 111/327 (33%), Gaps = 79/327 (24%) Query: 793 SPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPR-PRVFTPQSSPAMPLAPSHPS 851 SP P P+ E+ S Q Q P+ + P TP S A P P P+ Sbjct: 712 SPSIPSPQ--------DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 763 Query: 852 PYQGPRTQNISDYRAP-------GPQA---------IQPLPLSPGVRPASSQPQLLGGQR 895 P P + +P PQA IQ P RP S P Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP------ 817 Query: 896 VQVPNPVGFPGTWPLPGSPLPMACP--------GIMRPGSTSLPETPRLFPLLPLRPLGP 947 P+P P PL GS + P G PG SL P L P +P G Sbjct: 818 ---PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874 Query: 948 GRMVSHTPAPPASFPVP-------YLPGDPGA------PCSSVLPTTGILTPH--PGPQD 992 S AP + P LP A P LP + PH P P Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934 Query: 993 SWKEAPAPRGNLQRNKL--PETF-----MPPAPITAPVMSLT---------PELQGILPS 1036 + PAP+ + L P F +PP P P+ SL+ P LQ ++P Sbjct: 935 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQ 993 Query: 1037 QPPVSSVSHAPPGVPGELSLQLQHLPP 1063 P+ S PPG+ Q Q+LPP Sbjct: 994 SQPLPSSPAQPPGL-----TQSQNLPP 1015 Score = 50.1 bits (118), Expect = 1e-05 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 13/132 (9%) Query: 954 TPAPPASFP-VPYLPGDPGAPCSSVLPTTGILTPHPGP-QDSWKEAPAPRGNLQRNKLPE 1011 TPAP ++ P P LP P ++ +P G T P Q AP P ++Q+ Sbjct: 748 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807 Query: 1012 TFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPP-----GVPGELSLQ----LQHLP 1062 PP+P P S P LQ + S S+ SHA P G PG SLQ LQH Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH-- 865 Query: 1063 PEKMERKELPPE 1074 P + LPP+ Sbjct: 866 PGPPQPFGLPPQ 877 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 62.8 bits (151), Expect = 2e-09 Identities = 93/360 (25%), Positives = 124/360 (34%), Gaps = 72/360 (20%) Query: 728 LRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSA 787 L+ P GV+P P++ T L G +A + P+ P Q ++ Sbjct: 741 LQAPTGVTPAPSSAPPGTPQ---LPTPGPTPSATAVPPQ--GSPTASQAPNQ-------- 787 Query: 788 VLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPS-HQVPTPSPRPRVFTPQSSPAMPLA 846 Q+P P P H ++ + PS H P PSP P + S P A Sbjct: 788 ---PQAPTAPVPHT------HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838 Query: 847 PSHPSP---YQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVG 903 PSH P QGP PGP ++Q PL P QP L Q Q P+G Sbjct: 839 PSHAQPPLHGQGP----------PGPHSLQAGPLLQ--HPGPPQPFGLPPQASQGQAPLG 886 Query: 904 FPGTWPLPGSPLPM-----ACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPP 958 P + L + A P LP P P + P P + PAP Sbjct: 887 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQ 943 Query: 959 ASFPVPYLPGDPGAPCSSVLPTTGILTP------------HPGPQDSWKEA-PAPRGNLQ 1005 A P+L G ++ LP L P HP P ++ P P Q Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003 Query: 1006 RNKLPET-FMPPAPITAPVMSL------TPELQ------GILPSQPPVSSVSHAPPGVPG 1052 L ++ +PP P + P L P Q G P PP + PP PG Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063 Score = 58.9 bits (141), Expect = 3e-08 Identities = 81/284 (28%), Positives = 102/284 (35%), Gaps = 69/284 (24%) Query: 824 QVPTPSPRPRVFT--PQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQA-IQPLPLSPG 880 Q+PTP P P PQ SP AP+ P Q P AP P IQ P Sbjct: 760 QLPTPGPTPSATAVPPQGSPTASQAPNQP---QAPT--------APVPHTHIQQAPALHP 808 Query: 881 VRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLL 940 RP S P P+P P PL GS + P +P PL Sbjct: 809 QRPPSPHPP---------PHPSPHPPLQPLTGSAGQPSAPSHAQP------------PLH 847 Query: 941 PLRPLGP-----GRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWK 995 P GP G ++ H P PP F +P AP + + PH Q Sbjct: 848 GQGPPGPHSLQAGPLLQH-PGPPQPFGLPPQASQGQAPLGT---SPAAAYPHTSLQ---- 899 Query: 996 EAPAPRGNLQRNKLP-ETFMPPAPI---------TAPVMSLT--------PELQGILPSQ 1037 PA + LQ + P E +PPAP+ T P+ L P L G PS Sbjct: 900 -LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG--PSP 956 Query: 1038 PPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKSS 1081 +++ PP + SL H P +L P+ Q L SS Sbjct: 957 FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS 1000 Score = 56.6 bits (135), Expect = 1e-07 Identities = 88/327 (26%), Positives = 111/327 (33%), Gaps = 79/327 (24%) Query: 793 SPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPR-PRVFTPQSSPAMPLAPSHPS 851 SP P P+ E+ S Q Q P+ + P TP S A P P P+ Sbjct: 712 SPSIPSPQ--------DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 763 Query: 852 PYQGPRTQNISDYRAP-------GPQA---------IQPLPLSPGVRPASSQPQLLGGQR 895 P P + +P PQA IQ P RP S P Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP------ 817 Query: 896 VQVPNPVGFPGTWPLPGSPLPMACP--------GIMRPGSTSLPETPRLFPLLPLRPLGP 947 P+P P PL GS + P G PG SL P L P +P G Sbjct: 818 ---PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874 Query: 948 GRMVSHTPAPPASFPVP-------YLPGDPGA------PCSSVLPTTGILTPH--PGPQD 992 S AP + P LP A P LP + PH P P Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934 Query: 993 SWKEAPAPRGNLQRNKL--PETF-----MPPAPITAPVMSLT---------PELQGILPS 1036 + PAP+ + L P F +PP P P+ SL+ P LQ ++P Sbjct: 935 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQ 993 Query: 1037 QPPVSSVSHAPPGVPGELSLQLQHLPP 1063 P+ S PPG+ Q Q+LPP Sbjct: 994 SQPLPSSPAQPPGL-----TQSQNLPP 1015 Score = 50.1 bits (118), Expect = 1e-05 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 13/132 (9%) Query: 954 TPAPPASFP-VPYLPGDPGAPCSSVLPTTGILTPHPGP-QDSWKEAPAPRGNLQRNKLPE 1011 TPAP ++ P P LP P ++ +P G T P Q AP P ++Q+ Sbjct: 748 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807 Query: 1012 TFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPP-----GVPGELSLQ----LQHLP 1062 PP+P P S P LQ + S S+ SHA P G PG SLQ LQH Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH-- 865 Query: 1063 PEKMERKELPPE 1074 P + LPP+ Sbjct: 866 PGPPQPFGLPPQ 877 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 62.0 bits (149), Expect = 3e-09 Identities = 109/408 (26%), Positives = 147/408 (36%), Gaps = 67/408 (16%) Query: 735 SPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSP 794 SP P+ A+LLA S + A++ A P L A A L +P Sbjct: 1557 SPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPS--PAPPLAPLPVLAP 1614 Query: 795 -PFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPY 853 P P + T S G+ + P P+P P V P S+ M AP PSP Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTP-VLAPSSTQTMLPAPV-PSPL 1672 Query: 854 QGPRTQNISDYRAPGPQAIQPLPLSPGVRPA---SSQPQLLGGQRVQVPNPVGFPGTWPL 910 P P + Q L L+P + P SS Q L + NP G P Sbjct: 1673 -------------PSPASTQTLALAPALAPTLGGSSPSQTLS---LGTGNPQG-----PF 1711 Query: 911 PGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDP 970 P L + P S+ +P + L P PLGP + +S PAPP Sbjct: 1712 PTQTLSLT------PASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPL----------- 1754 Query: 971 GAPCSSVLPTTG-ILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAP----ITAPVMS 1025 AP S V P LT P + APA L + P + PA AP + Sbjct: 1755 -APASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813 Query: 1026 LTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKSSFEAL 1085 +P Q S VS+ AP V L + P+ + + PP S +SF Sbjct: 1814 QSPASQA---SSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGP 1870 Query: 1086 LQRCS----------LSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSP 1123 R L + + K KR+ E +R+ L E G L+P Sbjct: 1871 RPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSE--AHGALAP 1916 Score = 55.5 bits (132), Expect = 3e-07 Identities = 78/266 (29%), Positives = 103/266 (38%), Gaps = 47/266 (17%) Query: 815 YRLGSQPSHQV------PTPSPRPRVFTPQSSPA---------MPLAPSHPSPYQGPRTQ 859 + L SQP+H PTP P P P S+P+ +PLA + P T Sbjct: 1248 HHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTG 1307 Query: 860 NISDYRAPGPQ-AIQPL-PLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLP---GSP 914 + P+ + P+ PL+P RP SS G V P P PG P P + Sbjct: 1308 VVKIVVRQAPRDGLTPVPPLAPAPRPPSS-----GLPAVLNPRPTLTPGRLPTPTLGTAR 1362 Query: 915 LPMACPGIMRP----GSTSLPETPRLFP-LLPLRPLGPGRMVSHTPAPPASFPVPYLPGD 969 PM P ++RP + PE P PL P + S P PAS P+P Sbjct: 1363 APMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPG-PASSPMPIPNSS 1421 Query: 970 PGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPIT------APV 1023 P A S V T + P PAP P T AP+T A + Sbjct: 1422 PLA--SPVSSTVSVPLSSSLPISVPTTLPAPA------SAPLTIPISAPLTVSASGPALL 1473 Query: 1024 MSLTPELQGILPSQPPVSSVSHAPPG 1049 S+TP L ++P+ P S+ AP G Sbjct: 1474 TSVTPPLAPVVPAAPGPPSL--APSG 1497 Score = 53.9 bits (128), Expect = 9e-07 Identities = 70/221 (31%), Positives = 84/221 (38%), Gaps = 39/221 (17%) Query: 826 PTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPAS 885 P P R ++P PL P P GP +S PGP Q LP S V + Sbjct: 1000 PVPKQEGRTVVVVNNPRAPLGPVPVRPPPGP---ELSAQPTPGP-VPQVLPASLMVSASP 1055 Query: 886 SQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACP---GIMRPGSTSLPETPRLFPLLPL 942 + P L+ R P PV P P GS LP P G++ TS P TP L Sbjct: 1056 AGPPLIPASR--PPGPVLLPPLQPNSGS-LPQVLPSPLGVL--SGTSRPPTPTL------ 1104 Query: 943 RPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRG 1002 S P PPA PV P P S + P LT PG + PA Sbjct: 1105 ---------SLKPTPPA--PVRLSPAPPPGSSSLLKP----LTVPPG----YTFPPAAAT 1145 Query: 1003 NLQRNKLPETFMP-PAPITAPV-MSLTPELQGILPSQPPVS 1041 T PAP AP + L+P++Q LPS VS Sbjct: 1146 TTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVS 1186 Score = 51.6 bits (122), Expect = 4e-06 Identities = 75/272 (27%), Positives = 105/272 (38%), Gaps = 44/272 (16%) Query: 819 SQPSHQVPTPSP-RPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPL 877 + P P P+P + + P SS + LA + +P P+T ++ AP + L Sbjct: 1556 ASPFPSAPNPAPAQASLLAPASSASQALA-TPLAPMAAPQTAILAPSPAPPLAPLPVLAP 1614 Query: 878 SPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSL------- 930 SPG P + Q V V P PGT SP+P P ++ P ST Sbjct: 1615 SPGAAPVLASSQ----TPVPVMAPSSTPGTSLASASPVPAPTP-VLAPSSTQTMLPAPVP 1669 Query: 931 -----PETPRLFPLLP-LRPLGPGRMVSHTPA-----PPASFPVPYLPGDPGAPCSSVLP 979 P + + L P L P G S T + P FP L P SS++P Sbjct: 1670 SPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTL---SLTPASSLVP 1726 Query: 980 T---TGILTPHP--GPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQG-- 1032 T T L P P GP + APAP P + + PAP A ++L P Sbjct: 1727 TPAQTLSLAPGPPLGPTQTLSLAPAP------PLAPASPVGPAP--AHTLTLAPASSSAS 1778 Query: 1033 -ILPSQPPVSSVSHAPPGVPGELSLQLQHLPP 1063 + P+ ++S AP G + Q L P Sbjct: 1779 LLAPASVQTLTLSPAPVPTLGPAAAQTLALAP 1810 Score = 46.2 bits (108), Expect = 2e-04 Identities = 70/266 (26%), Positives = 92/266 (34%), Gaps = 64/266 (24%) Query: 840 SPAMPLAPSHPSPYQG------PR---------TQNISDYRAPGPQAIQPLPL-----SP 879 +P PLAP+ P G PR T + RAP P PL SP Sbjct: 1322 TPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSP 1381 Query: 880 GVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGS---PLPMACP-------GIMRPGSTS 929 ++S P G + + +P+ P + P P S P+P + P + P S+S Sbjct: 1382 SPEVSASAP---GAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSS 1438 Query: 930 LP-ETPRLFPLLPLRPL-------------GPGRMVSHTPAPPASFPVPYLPGDPGAPCS 975 LP P P PL GP + S TP P + VP PG P S Sbjct: 1439 LPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTP--PLAPVVPAAPGPPSLAPS 1496 Query: 976 SVLPTTGILTPHPGPQDSWKEAPAPRGNL----QRNKLPETFMPPAPITAPVMSLTPELQ 1031 P+ LT S + P L + +P AP +PV+ L Sbjct: 1497 GASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALA 1556 Query: 1032 GILPSQP-----------PVSSVSHA 1046 PS P P SS S A Sbjct: 1557 SPFPSAPNPAPAQASLLAPASSASQA 1582 Score = 36.6 bits (83), Expect = 0.14 Identities = 76/318 (23%), Positives = 101/318 (31%), Gaps = 81/318 (25%) Query: 819 SQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLS 878 S +VP P+PRPR TP S+PA A+ P+P+S Sbjct: 2430 SPARERVPRPAPRPRP-TPASAPA-------------------------AIPALVPVPVS 2463 Query: 879 PGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPE-TPRLF 937 V + PNP+ LP P P P P T P TP Sbjct: 2464 APVP-------------ISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTP--- 2507 Query: 938 PLLPLRPLGPGRMVSHTPAPPASFPV----PYLPGDPGAPCSS--------VLPTTGILT 985 +HTP P + V P L G P P S+ + P + Sbjct: 2508 ------------PPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCA 2555 Query: 986 PHPGPQDSWKEAPAPRGNLQRNKL--PETFMPPA----PITAPVMSLTPELQGIL--PSQ 1037 +S + A L P+ +P A P++ +SLTP + Sbjct: 2556 QALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGS 2615 Query: 1038 PPVSSVSHAPPGVPGELSLQL---QHLP--PEKMERKELPPEHQSLKSSFEAL-LQRCSL 1091 P AP G L + LP + ELPP S + E L R S Sbjct: 2616 IPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSE 2675 Query: 1092 SATDLKTKRKLEEAAQRL 1109 T+ KT E Q L Sbjct: 2676 ELTEAKTPTSSPEKPQEL 2693 Score = 36.2 bits (82), Expect = 0.19 Identities = 78/318 (24%), Positives = 111/318 (34%), Gaps = 71/318 (22%) Query: 824 QVPTPSPRP-------RVFTPQSSPAMPLAPSHPSPYQGPRTQNISDY-----------R 865 + PT SP V P +S + +P PSP + PR + +D + Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQ 2740 Query: 866 APGPQAIQPLP-----LSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPL----- 915 PGP+ ++ LP + + Q G VP G T PGSP Sbjct: 2741 PPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVP---GVSETSASPGSPSVRSMS 2797 Query: 916 -PMACPGIMRP----GSTSLPETPRLFPLLPLRPL------------GPGRMVSHTP--- 955 P + P I P S+SLP TP P + R + G G +++ TP Sbjct: 2798 GPESSPPIGGPCEAAPSSSLP-TPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAV 2856 Query: 956 -----APPAS--FPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNK 1008 PP P G AP S++ T P PGP+ P L Sbjct: 2857 KRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGP 2916 Query: 1009 LPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMER 1068 P + P P+ P L+P ++ +PP P +PG +S E Sbjct: 2917 QP---LGPQPVHRPNPLLSP-VEKRRRGRPP--KARDLP--IPGTIS----SAGDGNSES 2964 Query: 1069 KELPPEHQSLKSSFEALL 1086 + PP H S + LL Sbjct: 2965 RTQPPPHPSPLTPLPPLL 2982 Score = 32.0 bits (71), Expect = 3.6 Identities = 53/223 (23%), Positives = 76/223 (34%), Gaps = 45/223 (20%) Query: 804 GATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISD 863 GA L + R +P + +P+ R S + + P GP T ++D Sbjct: 2846 GALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVAD 2905 Query: 864 YRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIM 923 ++P L PG PQ LG Q V PNP+ P G P Sbjct: 2906 ------PVLEP-QLIPG-------PQPLGPQPVHRPNPLLSPVEKRRRGRP--------- 2942 Query: 924 RPGSTSLPETPRLFPLLP--LRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTT 981 P + LP +P + G G S T PP P+ LP P ++V T Sbjct: 2943 -PKARDLP--------IPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTV 2993 Query: 982 GILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVM 1024 +T P +R + P+ P P PV+ Sbjct: 2994 TTVTISTSPP-----------KRKRGRPPKNPPSPRPSQLPVL 3025 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 61.6 bits (148), Expect = 4e-09 Identities = 73/260 (28%), Positives = 93/260 (35%), Gaps = 34/260 (13%) Query: 792 QSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPS 851 + PP P P + G + G P +P P P P P P+ P+ P+ Sbjct: 215 EKPPAP-PSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPP---PPGGLPLPPMPPTGPA 270 Query: 852 PYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASS--QPQLLGGQRVQVPNPVGFPGTWP 909 P GP PGP + P +PGV P + P G V P P P P Sbjct: 271 P-SGP----------PGPPQLPPP--APGVHPPAPVVHPPASG---VHPPAPGVHP---P 311 Query: 910 LPGSPLPMACPGIMRPGSTSLPETPRLFPLLP-LRPLGPGRMVSHTPAPPASFPVPYLPG 968 PG P PG+ P S P P + P P + P PG H PAP P P + Sbjct: 312 APGVHPP--APGVHPPTSGVHPPAPGVHPPAPGVHPPAPG---VHPPAPGVHPPAPGVHP 366 Query: 969 DPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTP 1028 P A P P PQ PAP + Q P P + + P Sbjct: 367 PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQ---APGVHPQPPGVHPSAPGVHP 423 Query: 1029 ELQGILPSQPPVSSVSHAPP 1048 + G+ PS P V + PP Sbjct: 424 QPPGVHPSNPGVHPPTPMPP 443 Score = 44.7 bits (104), Expect = 5e-04 Identities = 50/156 (32%), Positives = 58/156 (37%), Gaps = 37/156 (23%) Query: 909 PLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLP- 967 P P S LP PG+ RP P L LP RP P S P PP P+P +P Sbjct: 218 PAPPS-LPAGPPGVKRP-------PPPLMNGLPPRPPLP---ESLPPPPPGGLPLPPMPP 266 Query: 968 ------GDPGAPCSSVLPTTGILTPHP--GPQDSWKEAPAPRGNLQRNKLPETFMPPAP- 1018 G PG P P G+ P P P S PAP + PPAP Sbjct: 267 TGPAPSGPPGPP-QLPPPAPGVHPPAPVVHPPASGVHPPAPGVH-----------PPAPG 314 Query: 1019 ITAPVMSLTPELQGILPS----QPPVSSVSHAPPGV 1050 + P + P G+ P PP V PGV Sbjct: 315 VHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGV 350 Score = 31.6 bits (70), Expect = 4.7 Identities = 25/82 (30%), Positives = 27/82 (32%), Gaps = 20/82 (24%) Query: 970 PGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPE 1029 P AP S G+ P P P G R LPE+ PP P P Sbjct: 217 PPAPPSLPAGPPGVKRPPP---------PLMNGLPPRPPLPESLPPPPPGGLP------- 260 Query: 1030 LQGILPSQPPVSSVSHAPPGVP 1051 LP PP PPG P Sbjct: 261 ----LPPMPPTGPAPSGPPGPP 278 Score = 31.6 bits (70), Expect = 4.7 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 10/92 (10%) Query: 824 QVPTPSPRPRVFTPQSSPAMPLAPS-HP-SPYQGPRTQNISDYRAPG--PQAIQPLPLSP 879 Q P P PQ+ P AP HP +P P+ + APG PQ P +P Sbjct: 375 QAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHP-SAPGVHPQPPGVHPSNP 433 Query: 880 GVRPASSQPQLLGGQRVQVPNPVGFPGTWPLP 911 GV P + P +L + P P PG P P Sbjct: 434 GVHPPTPMPPML-----RPPLPSEGPGNIPPP 460 >gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] Length = 831 Score = 60.5 bits (145), Expect = 9e-09 Identities = 79/282 (28%), Positives = 96/282 (34%), Gaps = 38/282 (13%) Query: 821 PSHQVPTPSPRPRVFTP---------QSSPAMPLAPS---HPSPYQGPRTQNISDYRAPG 868 P +P+ P P F+P P +P A S H S + + +N PG Sbjct: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN----SCPG 364 Query: 869 PQAIQPLPLSPGVRPASSQPQL----LGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMR 924 P S + P +P+L + + P P PG P P P P M Sbjct: 365 PLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPP-----MA 419 Query: 925 PGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPY-LPGDPGAPCSSVLPTTGI 983 P + L E P P P + P VS PAP A P P +P P L G Sbjct: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGY 479 Query: 984 LTPHPGPQDSWKE----APAPRGNLQR--NKLPETFMPPAPITAPVMSLTPELQGILPSQ 1037 P GP S AP+PRG P T PP + LT L P Q Sbjct: 480 SEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ 539 Query: 1038 ----PPVSSVSHAPPGVPGEL--SLQLQHLPPEKMERKELPP 1073 P VSS PG P E LPP PP Sbjct: 540 ALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP 581 Score = 47.8 bits (112), Expect = 6e-05 Identities = 91/352 (25%), Positives = 126/352 (35%), Gaps = 88/352 (25%) Query: 794 PPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAP-SHPSP 852 PP PFP + L +E P PT P P V + A P P S PSP Sbjct: 411 PPPPFPPMAPPTALLQEEPLF-----SPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSP 465 Query: 853 YQGPRTQNISDYRAPGPQAIQPLPLS---PGVRPASSQPQLLGGQRVQVPNPVGFPGTWP 909 AP P I+ LPL P P S P+ + P+P G Sbjct: 466 -------------APTPFPIELLPLGYSEPAFGPCFSMPR----GKPPAPSPRG------ 502 Query: 910 LPGSPLPMACPGIMRPGSTSLPETPRLFPLL----PLRPLGPGRMVSHTPAPPASFPVPY 965 SP P P P +T+ P L LL P + L P + S P S Sbjct: 503 QKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS----- 556 Query: 966 LPGD--PGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPV 1023 P + P PC+ + PT P P P P T P P+ Sbjct: 557 -PQETVPEFPCTFLPPTPAPTPPRPPPG------------------PATLAPSRPL---- 593 Query: 1024 MSLTPELQGILPSQPPVSS--VSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQ----- 1076 L P+ + + P P S +S +PG +L ++ PP+ + + P ++ Sbjct: 594 --LVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRIT 651 Query: 1077 ----------SLKSSFEALLQRCS-LSA-TDLKTKRKLEEAAQRLEYLYEKL 1116 ++K F+ L S LSA LK + L+E AQ+L E+L Sbjct: 652 HISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEEL 703 Score = 37.0 bits (84), Expect = 0.11 Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 26/187 (13%) Query: 758 ATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRL 817 A +S LP A PP Q +V PFP + +G + E + Sbjct: 443 APGVSPLPAPAAFPPTPQ-----------SVPSPAPTPFPIELLPLGYS----EPAFGPC 487 Query: 818 GSQPSHQVPTPSPRPRVFTPQS-SPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLP 876 S P + P PSPR + +P + +PA P+ TQ ++ A QA++P Sbjct: 488 FSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT--AAKPEQALEPPL 545 Query: 877 LSPGVRPASSQPQLLGGQRVQVPN-PVGFPGTWPLPGSPLPMACPGIMRPGSTSL-PETP 934 +S + + PQ VP P F P P P P P + P L P+ Sbjct: 546 VSSTLLRSPGSPQ------ETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAE 599 Query: 935 RLFPLLP 941 RL P P Sbjct: 600 RLSPPAP 606 >gi|14602437 Williams Beuren syndrome chromosome region 14 isoform gamma [Homo sapiens] Length = 850 Score = 60.5 bits (145), Expect = 9e-09 Identities = 79/282 (28%), Positives = 96/282 (34%), Gaps = 38/282 (13%) Query: 821 PSHQVPTPSPRPRVFTP---------QSSPAMPLAPS---HPSPYQGPRTQNISDYRAPG 868 P +P+ P P F+P P +P A S H S + + +N PG Sbjct: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN----SCPG 364 Query: 869 PQAIQPLPLSPGVRPASSQPQL----LGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMR 924 P S + P +P+L + + P P PG P P P P M Sbjct: 365 PLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPP-----MA 419 Query: 925 PGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPY-LPGDPGAPCSSVLPTTGI 983 P + L E P P P + P VS PAP A P P +P P L G Sbjct: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGY 479 Query: 984 LTPHPGPQDSWKE----APAPRGNLQR--NKLPETFMPPAPITAPVMSLTPELQGILPSQ 1037 P GP S AP+PRG P T PP + LT L P Q Sbjct: 480 SEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ 539 Query: 1038 ----PPVSSVSHAPPGVPGEL--SLQLQHLPPEKMERKELPP 1073 P VSS PG P E LPP PP Sbjct: 540 ALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP 581 Score = 44.7 bits (104), Expect = 5e-04 Identities = 75/296 (25%), Positives = 104/296 (35%), Gaps = 71/296 (23%) Query: 794 PPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAP-SHPSP 852 PP PFP + L +E P PT P P V + A P P S PSP Sbjct: 411 PPPPFPPMAPPTALLQEEPLF-----SPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSP 465 Query: 853 YQGPRTQNISDYRAPGPQAIQPLPLS---PGVRPASSQPQLLGGQRVQVPNPVGFPGTWP 909 AP P I+ LPL P P S P+ + P+P G Sbjct: 466 -------------APTPFPIELLPLGYSEPAFGPCFSMPR----GKPPAPSPRG------ 502 Query: 910 LPGSPLPMACPGIMRPGSTSLPETPRLFPLL----PLRPLGPGRMVSHTPAPPASFPVPY 965 SP P P P +T+ P L LL P + L P + S P S Sbjct: 503 QKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS----- 556 Query: 966 LPGD--PGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPV 1023 P + P PC+ + PT P P P P T P P+ Sbjct: 557 -PQETVPEFPCTFLPPTPAPTPPRPPPG------------------PATLAPSRPL---- 593 Query: 1024 MSLTPELQGILPSQPPVSS--VSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQS 1077 L P+ + + P P S +S +PG +L ++ PP+ + + P +++ Sbjct: 594 --LVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKN 647 Score = 37.0 bits (84), Expect = 0.11 Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 26/187 (13%) Query: 758 ATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRL 817 A +S LP A PP Q +V PFP + +G + E + Sbjct: 443 APGVSPLPAPAAFPPTPQ-----------SVPSPAPTPFPIELLPLGYS----EPAFGPC 487 Query: 818 GSQPSHQVPTPSPRPRVFTPQS-SPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLP 876 S P + P PSPR + +P + +PA P+ TQ ++ A QA++P Sbjct: 488 FSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT--AAKPEQALEPPL 545 Query: 877 LSPGVRPASSQPQLLGGQRVQVPN-PVGFPGTWPLPGSPLPMACPGIMRPGSTSL-PETP 934 +S + + PQ VP P F P P P P P + P L P+ Sbjct: 546 VSSTLLRSPGSPQ------ETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAE 599 Query: 935 RLFPLLP 941 RL P P Sbjct: 600 RLSPPAP 606 >gi|14602435 Williams Beuren syndrome chromosome region 14 isoform beta [Homo sapiens] Length = 833 Score = 60.5 bits (145), Expect = 9e-09 Identities = 79/282 (28%), Positives = 96/282 (34%), Gaps = 38/282 (13%) Query: 821 PSHQVPTPSPRPRVFTP---------QSSPAMPLAPS---HPSPYQGPRTQNISDYRAPG 868 P +P+ P P F+P P +P A S H S + + +N PG Sbjct: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN----SCPG 364 Query: 869 PQAIQPLPLSPGVRPASSQPQL----LGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMR 924 P S + P +P+L + + P P PG P P P P M Sbjct: 365 PLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPP-----MA 419 Query: 925 PGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPY-LPGDPGAPCSSVLPTTGI 983 P + L E P P P + P VS PAP A P P +P P L G Sbjct: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGY 479 Query: 984 LTPHPGPQDSWKE----APAPRGNLQR--NKLPETFMPPAPITAPVMSLTPELQGILPSQ 1037 P GP S AP+PRG P T PP + LT L P Q Sbjct: 480 SEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ 539 Query: 1038 ----PPVSSVSHAPPGVPGEL--SLQLQHLPPEKMERKELPP 1073 P VSS PG P E LPP PP Sbjct: 540 ALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP 581 Score = 47.0 bits (110), Expect = 1e-04 Identities = 91/354 (25%), Positives = 126/354 (35%), Gaps = 90/354 (25%) Query: 794 PPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAP-SHPSP 852 PP PFP + L +E P PT P P V + A P P S PSP Sbjct: 411 PPPPFPPMAPPTALLQEEPLF-----SPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSP 465 Query: 853 YQGPRTQNISDYRAPGPQAIQPLPLS---PGVRPASSQPQLLGGQRVQVPNPVGFPGTWP 909 AP P I+ LPL P P S P+ + P+P G Sbjct: 466 -------------APTPFPIELLPLGYSEPAFGPCFSMPR----GKPPAPSPRG------ 502 Query: 910 LPGSPLPMACPGIMRPGSTSLPETPRLFPLL----PLRPLGPGRMVSHTPAPPASFPVPY 965 SP P P P +T+ P L LL P + L P + S P S Sbjct: 503 QKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS----- 556 Query: 966 LPGD--PGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPV 1023 P + P PC+ + PT P P P P T P P+ Sbjct: 557 -PQETVPEFPCTFLPPTPAPTPPRPPPG------------------PATLAPSRPL---- 593 Query: 1024 MSLTPELQGILPSQPPVSS--VSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQ----- 1076 L P+ + + P P S +S +PG +L ++ PP+ + + P ++ Sbjct: 594 --LVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRR 651 Query: 1077 ------------SLKSSFEALLQRCS-LSA-TDLKTKRKLEEAAQRLEYLYEKL 1116 ++K F+ L S LSA LK + L+E AQ+L E+L Sbjct: 652 ITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEEL 705 Score = 37.0 bits (84), Expect = 0.11 Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 26/187 (13%) Query: 758 ATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRL 817 A +S LP A PP Q +V PFP + +G + E + Sbjct: 443 APGVSPLPAPAAFPPTPQ-----------SVPSPAPTPFPIELLPLGYS----EPAFGPC 487 Query: 818 GSQPSHQVPTPSPRPRVFTPQS-SPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLP 876 S P + P PSPR + +P + +PA P+ TQ ++ A QA++P Sbjct: 488 FSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT--AAKPEQALEPPL 545 Query: 877 LSPGVRPASSQPQLLGGQRVQVPN-PVGFPGTWPLPGSPLPMACPGIMRPGSTSL-PETP 934 +S + + PQ VP P F P P P P P + P L P+ Sbjct: 546 VSSTLLRSPGSPQ------ETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAE 599 Query: 935 RLFPLLP 941 RL P P Sbjct: 600 RLSPPAP 606 >gi|14602433 Williams Beuren syndrome chromosome region 14 isoform alpha [Homo sapiens] Length = 852 Score = 60.5 bits (145), Expect = 9e-09 Identities = 79/282 (28%), Positives = 96/282 (34%), Gaps = 38/282 (13%) Query: 821 PSHQVPTPSPRPRVFTP---------QSSPAMPLAPS---HPSPYQGPRTQNISDYRAPG 868 P +P+ P P F+P P +P A S H S + + +N PG Sbjct: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN----SCPG 364 Query: 869 PQAIQPLPLSPGVRPASSQPQL----LGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMR 924 P S + P +P+L + + P P PG P P P P M Sbjct: 365 PLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPP-----MA 419 Query: 925 PGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPY-LPGDPGAPCSSVLPTTGI 983 P + L E P P P + P VS PAP A P P +P P L G Sbjct: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGY 479 Query: 984 LTPHPGPQDSWKE----APAPRGNLQR--NKLPETFMPPAPITAPVMSLTPELQGILPSQ 1037 P GP S AP+PRG P T PP + LT L P Q Sbjct: 480 SEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ 539 Query: 1038 ----PPVSSVSHAPPGVPGEL--SLQLQHLPPEKMERKELPP 1073 P VSS PG P E LPP PP Sbjct: 540 ALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP 581 Score = 45.1 bits (105), Expect = 4e-04 Identities = 83/327 (25%), Positives = 114/327 (34%), Gaps = 55/327 (16%) Query: 794 PPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAP-SHPSP 852 PP PFP + L +E P PT P P V + A P P S PSP Sbjct: 411 PPPPFPPMAPPTALLQEEPLF-----SPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSP 465 Query: 853 YQGPRTQNISDYRAPGPQAIQPLPLS---PGVRPASSQPQLLGGQRVQVPNPVGFPGTWP 909 AP P I+ LPL P P S P+ + P+P G Sbjct: 466 -------------APTPFPIELLPLGYSEPAFGPCFSMPR----GKPPAPSPRG------ 502 Query: 910 LPGSPLPMACPGIMRPGSTSLPETPRLFPLL----PLRPLGPGRMVSHTPAPPASFPVPY 965 SP P P P +T+ P L LL P + L P + S P S Sbjct: 503 QKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS----- 556 Query: 966 LPGD--PGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAP----- 1018 P + P PC+ + PT P P P + AP L K E PPAP Sbjct: 557 -PQETVPEFPCTFLPPTPAPTPPRPPPGPA---TLAPSRPLLVPK-AERLSPPAPSGSER 611 Query: 1019 -ITAPVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQS 1077 ++ + S+ + PP +S P + ++ H+ E+ R + + Sbjct: 612 RLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDT 671 Query: 1078 LKSSFEALLQRCSLSATDLKTKRKLEE 1104 L L + SL + T +K E Sbjct: 672 LHGLVSTLSAQPSLKVSKATTLQKTAE 698 Score = 37.0 bits (84), Expect = 0.11 Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 26/187 (13%) Query: 758 ATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRL 817 A +S LP A PP Q +V PFP + +G + E + Sbjct: 443 APGVSPLPAPAAFPPTPQ-----------SVPSPAPTPFPIELLPLGYS----EPAFGPC 487 Query: 818 GSQPSHQVPTPSPRPRVFTPQS-SPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLP 876 S P + P PSPR + +P + +PA P+ TQ ++ A QA++P Sbjct: 488 FSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT--AAKPEQALEPPL 545 Query: 877 LSPGVRPASSQPQLLGGQRVQVPN-PVGFPGTWPLPGSPLPMACPGIMRPGSTSL-PETP 934 +S + + PQ VP P F P P P P P + P L P+ Sbjct: 546 VSSTLLRSPGSPQ------ETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAE 599 Query: 935 RLFPLLP 941 RL P P Sbjct: 600 RLSPPAP 606 >gi|117938768 GNAS complex locus alex [Homo sapiens] Length = 626 Score = 59.3 bits (142), Expect = 2e-08 Identities = 104/386 (26%), Positives = 144/386 (37%), Gaps = 81/386 (20%) Query: 712 QDLMEKVMVLNRSLEQL------RGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLP 765 Q L+++ VL S E L G ++P AT + + +L + L T P Sbjct: 120 QTLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAH--P 177 Query: 766 RDCAQPPVQQLRDRLFHAQGSAVLGQQSPPF-------PFPRIVVGA----TLHSKETSS 814 R + L H +A +QS P P R+ G+ H K S Sbjct: 178 RGFPE---------LSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSD 228 Query: 815 YRLGSQPSHQV-PTPSPRPRVFTPQSSPAMPLAPSH-PSPYQGPRTQ-NISDYRAPGPQA 871 L S+ + +P PR R+ P PL + PS + P+++ R+P PQ Sbjct: 229 LLLTSRAAAPGWRSPDPRSRLAAP------PLGSTTLPSTWTAPQSRLTARPSRSPEPQI 282 Query: 872 IQPLPLSPGVR--------PASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIM 923 + P +R P + + R P P G P PLPG PL Sbjct: 283 RESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPL-------- 334 Query: 924 RPGSTSLPETPRLFPLLPLRPLGPGRMVSHTP--APPASFPVPYLPGDPGAPCSSVLPTT 981 +P P P+ P PG+ H P P S P+P PG P P +PT Sbjct: 335 QPQPILTPGQPQKIPT-------PGQ---HQPILTPGHSQPIP-TPGQPLPP--QPIPTP 381 Query: 982 G-ILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPEL---QGILPSQ 1037 G LTP P P P P +Q P PP + P ++P+L QG+ Q Sbjct: 382 GRPLTPQPIPTPGRPLTPQP---IQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQ 438 Query: 1038 PPVSSVSHAPPGVPGELSLQLQHLPP 1063 P + PPG P LQ LPP Sbjct: 439 PLL------PPGQPKSAGRPLQPLPP 458 Score = 44.7 bits (104), Expect = 5e-04 Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 14/177 (7%) Query: 821 PSHQVPTPSP-RPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSP 879 P H P P+P +P P +P PL P P P G R + PG P PL Sbjct: 360 PGHSQPIPTPGQPLPPQPIPTPGRPLTPQ-PIPTPG-RPLTPQPIQMPGRPLRLPPPLRL 417 Query: 880 GVRPASSQ-PQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFP 938 +RP PQL Q + +P P+ PG G PL PG P + S+ + P Sbjct: 418 -LRPGQPMSPQLRQTQGLPLPQPLLPPGQPKSAGRPLQPLPPG---PDARSISDPPAPRS 473 Query: 939 LLPLRPLGPGRMVSHTP--APPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDS 993 LP+R L +++ P A P + G P +++ P +P GP D+ Sbjct: 474 RLPIRLL--RGLLARLPGGASPRAAAAAACTTMKGWPAATMTPAE--TSPTMGPPDA 526 >gi|40807452 peroxisome proliferator-activated receptor gamma, coactivator-related 1 [Homo sapiens] Length = 1664 Score = 59.3 bits (142), Expect = 2e-08 Identities = 91/298 (30%), Positives = 117/298 (39%), Gaps = 75/298 (25%) Query: 827 TPSPRPRVFTPQSSPAMPLAPSHPSPY---QGPRTQNIS-------------DYRAPG-- 868 +PSP P V P +S PS P P Q++S + A G Sbjct: 828 SPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLG 887 Query: 869 -PQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGS 927 P ++ P PL P P S P L P+P F PLP P P + Sbjct: 888 MPPSLPPPPLQPPSLPLSMGPVL--------PDP--FTHYAPLPSWP---CYPHV----- 929 Query: 928 TSLPETPRLFPLLPLRPLGPGRMVSHTP---APPASFPVPYLPGDPGAPCS--SVLPTTG 982 +P +P LP P P +VS TP A P + VP+ P P AP S S T G Sbjct: 930 -----SPSGYPCLPPPPTVP--LVSGTPGAYAVPPTCSVPWAP--PPAPVSPYSSTCTYG 980 Query: 983 ILTPHPGPQDS--WKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPP- 1039 L PGPQ + W P P +PPA I V E +G P+ PP Sbjct: 981 PLGWGPGPQHAPFWSTVPPPP------------LPPASIGRAVPQPKMESRG-TPAGPPE 1027 Query: 1040 -VSSVSHAPP---GVPGELSLQLQHLPPEKMERKELPPEHQSLKSSFEALLQRCSLSA 1093 V +S APP G+PG + Q + P K+E K +P K AL+Q + A Sbjct: 1028 NVLPLSMAPPLSLGLPGHGAPQTE---PTKVEVKPVPASPHP-KHKVSALVQSPQMKA 1081 >gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] Length = 526 Score = 59.3 bits (142), Expect = 2e-08 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 29/238 (12%) Query: 104 HILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSK 163 H + G V + K V +LD N G LLA+G+ D IW + N+ TLG Sbjct: 225 HCIREGGHDVPSNKD-----VTSLDWNT-NGTLLATGSYDGFARIWTEDG-NLASTLG-- 275 Query: 164 SQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHP 223 Q I AL WNR+ +IL SA ++WD E + HS + W Sbjct: 276 --QHKGPIFALKWNRKGNYIL-SAGVDKTTIIWDAHTGEAKQQFPFHS--APALDVDWQN 330 Query: 224 DIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDS 283 + T CS D + V +L P+K + H+ + ++ W + LL + + D Sbjct: 331 N--TTFASCSTDMCIHVCRLG----CDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDM 383 Query: 284 QILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPS--------VFSAASFNGWISLYSV 333 + ++ ++ L + + ++W P P+ + ++ASF+ + L+ + Sbjct: 384 TLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441 Score = 31.2 bits (69), Expect = 6.1 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%) Query: 119 KHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNR 178 KH V ++ +P G LASG+ D + IW+ + N+ S + I + WN Sbjct: 452 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQSGNL-----VHSYRGTGGIFEVCWNA 505 Query: 179 QAQHILSSAHPSGKAVVWDLRK 200 + + +SA G V DLRK Sbjct: 506 RGDKVGASA-SDGSVCVLDLRK 526 >gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] Length = 526 Score = 59.3 bits (142), Expect = 2e-08 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 29/238 (12%) Query: 104 HILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSK 163 H + G V + K V +LD N G LLA+G+ D IW + N+ TLG Sbjct: 225 HCIREGGHDVPSNKD-----VTSLDWNT-NGTLLATGSYDGFARIWTEDG-NLASTLG-- 275 Query: 164 SQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHP 223 Q I AL WNR+ +IL SA ++WD E + HS + W Sbjct: 276 --QHKGPIFALKWNRKGNYIL-SAGVDKTTIIWDAHTGEAKQQFPFHS--APALDVDWQN 330 Query: 224 DIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDS 283 + T CS D + V +L P+K + H+ + ++ W + LL + + D Sbjct: 331 N--TTFASCSTDMCIHVCRLG----CDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDM 383 Query: 284 QILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPS--------VFSAASFNGWISLYSV 333 + ++ ++ L + + ++W P P+ + ++ASF+ + L+ + Sbjct: 384 TLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441 Score = 31.2 bits (69), Expect = 6.1 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%) Query: 119 KHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNR 178 KH V ++ +P G LASG+ D + IW+ + N+ S + I + WN Sbjct: 452 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQSGNL-----VHSYRGTGGIFEVCWNA 505 Query: 179 QAQHILSSAHPSGKAVVWDLRK 200 + + +SA G V DLRK Sbjct: 506 RGDKVGASA-SDGSVCVLDLRK 526 >gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] Length = 577 Score = 59.3 bits (142), Expect = 2e-08 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 29/238 (12%) Query: 104 HILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSK 163 H + G V + K V +LD N G LLA+G+ D IW + N+ TLG Sbjct: 276 HCIREGGHDVPSNKD-----VTSLDWNT-NGTLLATGSYDGFARIWTEDG-NLASTLG-- 326 Query: 164 SQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHP 223 Q I AL WNR+ +IL SA ++WD E + HS + W Sbjct: 327 --QHKGPIFALKWNRKGNYIL-SAGVDKTTIIWDAHTGEAKQQFPFHS--APALDVDWQN 381 Query: 224 DIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDS 283 + T CS D + V +L P+K + H+ + ++ W + LL + + D Sbjct: 382 N--TTFASCSTDMCIHVCRLG----CDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDM 434 Query: 284 QILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPS--------VFSAASFNGWISLYSV 333 + ++ ++ L + + ++W P P+ + ++ASF+ + L+ + Sbjct: 435 TLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492 Score = 31.2 bits (69), Expect = 6.1 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%) Query: 119 KHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNR 178 KH V ++ +P G LASG+ D + IW+ + N+ S + I + WN Sbjct: 503 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQSGNL-----VHSYRGTGGIFEVCWNA 556 Query: 179 QAQHILSSAHPSGKAVVWDLRK 200 + + +SA G V DLRK Sbjct: 557 RGDKVGASA-SDGSVCVLDLRK 577 >gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] Length = 577 Score = 59.3 bits (142), Expect = 2e-08 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 29/238 (12%) Query: 104 HILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSK 163 H + G V + K V +LD N G LLA+G+ D IW + N+ TLG Sbjct: 276 HCIREGGHDVPSNKD-----VTSLDWNT-NGTLLATGSYDGFARIWTEDG-NLASTLG-- 326 Query: 164 SQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHP 223 Q I AL WNR+ +IL SA ++WD E + HS + W Sbjct: 327 --QHKGPIFALKWNRKGNYIL-SAGVDKTTIIWDAHTGEAKQQFPFHS--APALDVDWQN 381 Query: 224 DIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDS 283 + T CS D + V +L P+K + H+ + ++ W + LL + + D Sbjct: 382 N--TTFASCSTDMCIHVCRLG----CDRPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDM 434 Query: 284 QILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPS--------VFSAASFNGWISLYSV 333 + ++ ++ L + + ++W P P+ + ++ASF+ + L+ + Sbjct: 435 TLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492 Score = 31.2 bits (69), Expect = 6.1 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%) Query: 119 KHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNR 178 KH V ++ +P G LASG+ D + IW+ + N+ S + I + WN Sbjct: 503 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQSGNL-----VHSYRGTGGIFEVCWNA 556 Query: 179 QAQHILSSAHPSGKAVVWDLRK 200 + + +SA G V DLRK Sbjct: 557 RGDKVGASA-SDGSVCVLDLRK 577 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 53,797,019 Number of Sequences: 37866 Number of extensions: 3200335 Number of successful extensions: 20808 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 1192 Number of HSP's that attempted gapping in prelim test: 13698 Number of HSP's gapped (non-prelim): 5489 length of query: 1179 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1066 effective length of database: 13,968,660 effective search space: 14890591560 effective search space used: 14890591560 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.