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Search of human proteins with 87162455
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
(1309 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87162455 hypothetical protein LOC23277 [Homo sapiens] 2630 0.0
gi|34304360 nephrocystin 3 [Homo sapiens] 70 2e-11
gi|239756576 PREDICTED: cyclin Y-like 3 [Homo sapiens] 66 2e-10
gi|239748884 PREDICTED: cyclin Y-like 3 [Homo sapiens] 66 2e-10
gi|239745552 PREDICTED: cyclin Y-like 3 [Homo sapiens] 66 2e-10
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 65 6e-10
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 65 6e-10
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 65 6e-10
gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 62 4e-09
gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 62 4e-09
gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 62 4e-09
gi|91825557 kinesin light chain 3 [Homo sapiens] 60 1e-08
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens] 55 4e-07
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens] 55 4e-07
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens] 55 4e-07
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens] 55 4e-07
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho... 44 8e-04
gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens] 40 0.019
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 34 1.1
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 34 1.1
gi|16579828 zinc finger protein 91 [Homo sapiens] 33 1.4
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 33 1.8
gi|20532340 angiopoietin 1 [Homo sapiens] 33 2.3
gi|110611908 mitogen-activated protein kinase kinase kinase kina... 33 2.3
gi|6005810 mitogen-activated protein kinase kinase kinase kinase... 33 2.3
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 33 2.3
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom... 32 3.1
gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens] 32 4.0
gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens] 32 4.0
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni... 32 4.0
>gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
Length = 1309
Score = 2630 bits (6816), Expect = 0.0
Identities = 1309/1309 (100%), Positives = 1309/1309 (100%)
Query: 1 MLLNGDCPESLKKEAAAAEPPRENGLDEAGPGDETTGQEVIVIQDTGFSVKILAPGIEPF 60
MLLNGDCPESLKKEAAAAEPPRENGLDEAGPGDETTGQEVIVIQDTGFSVKILAPGIEPF
Sbjct: 1 MLLNGDCPESLKKEAAAAEPPRENGLDEAGPGDETTGQEVIVIQDTGFSVKILAPGIEPF 60
Query: 61 SLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDHFSELRSVEGLQEGSVLRVVE 120
SLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDHFSELRSVEGLQEGSVLRVVE
Sbjct: 61 SLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDHFSELRSVEGLQEGSVLRVVE 120
Query: 121 EPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMD 180
EPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMD
Sbjct: 121 EPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMD 180
Query: 181 PIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLF 240
PIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLF
Sbjct: 181 PIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLF 240
Query: 241 VITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVL 300
VITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVL
Sbjct: 241 VITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVL 300
Query: 301 QKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEE 360
QKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEE
Sbjct: 301 QKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEE 360
Query: 361 LQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFI 420
LQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFI
Sbjct: 361 LQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFI 420
Query: 421 WNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGY 480
WNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGY
Sbjct: 421 WNNIFFSLGFDVRDHYKDFGGDVAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGY 480
Query: 481 RVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHQVLNDRD 540
RVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHQVLNDRD
Sbjct: 481 RVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHQVLNDRD 540
Query: 541 EEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEELPEECARAGFPRAHRHK 600
EEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEELPEECARAGFPRAHRHK
Sbjct: 541 EEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEELPEECARAGFPRAHRHK 600
Query: 601 LCCLRQELVDAFVEHRYLLFMKLAALQLMQQNASQLETPSSLENGGPSSLESKSEDPPGQ 660
LCCLRQELVDAFVEHRYLLFMKLAALQLMQQNASQLETPSSLENGGPSSLESKSEDPPGQ
Sbjct: 601 LCCLRQELVDAFVEHRYLLFMKLAALQLMQQNASQLETPSSLENGGPSSLESKSEDPPGQ 660
Query: 661 EAGSEEEGSSASGLAKVKELAETIAADDGTDPRSREVIRNACKAVGSISSTAFDIRFNPD 720
EAGSEEEGSSASGLAKVKELAETIAADDGTDPRSREVIRNACKAVGSISSTAFDIRFNPD
Sbjct: 661 EAGSEEEGSSASGLAKVKELAETIAADDGTDPRSREVIRNACKAVGSISSTAFDIRFNPD 720
Query: 721 IFSPGVRFPESCQDEVRDQKQLLKDAAAFLLSCQIPGLVKDCMEHAVLPVDGATLAEVMR 780
IFSPGVRFPESCQDEVRDQKQLLKDAAAFLLSCQIPGLVKDCMEHAVLPVDGATLAEVMR
Sbjct: 721 IFSPGVRFPESCQDEVRDQKQLLKDAAAFLLSCQIPGLVKDCMEHAVLPVDGATLAEVMR 780
Query: 781 QRGINMRYLGKVLELVLRSPARHQLDHVFKIGIGELITRSAKHIFKTYLQGVELSGLSAA 840
QRGINMRYLGKVLELVLRSPARHQLDHVFKIGIGELITRSAKHIFKTYLQGVELSGLSAA
Sbjct: 781 QRGINMRYLGKVLELVLRSPARHQLDHVFKIGIGELITRSAKHIFKTYLQGVELSGLSAA 840
Query: 841 ISHFLNCFLSSYPNPVAHLPADELVSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQ 900
ISHFLNCFLSSYPNPVAHLPADELVSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQ
Sbjct: 841 ISHFLNCFLSSYPNPVAHLPADELVSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQ 900
Query: 901 EAKNYFDFDLECETVDQAVETYGLQKITLLREISLKTGIQVLLKEYSFDSRHKPAFTEED 960
EAKNYFDFDLECETVDQAVETYGLQKITLLREISLKTGIQVLLKEYSFDSRHKPAFTEED
Sbjct: 901 EAKNYFDFDLECETVDQAVETYGLQKITLLREISLKTGIQVLLKEYSFDSRHKPAFTEED 960
Query: 961 VLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVETC 1020
VLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVETC
Sbjct: 961 VLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVETC 1020
Query: 1021 ACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLST 1080
ACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLST
Sbjct: 1021 ACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLST 1080
Query: 1081 ALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGP 1140
ALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGP
Sbjct: 1081 ALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGP 1140
Query: 1141 KALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ 1200
KALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ
Sbjct: 1141 KALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ 1200
Query: 1201 AVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEV 1260
AVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEV
Sbjct: 1201 AVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEV 1260
Query: 1261 ARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAAKDPSPSVQG 1309
ARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAAKDPSPSVQG
Sbjct: 1261 ARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAAKDPSPSVQG 1309
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/245 (24%), Positives = 102/245 (41%), Gaps = 6/245 (2%)
Query: 974 KASDAFHFFQSGQAKVQQGFLKEG-----CELINEALNLFNNVYGAMHVETCACLRLLAR 1028
K A HF + Q+ K+G L AL L G + L L
Sbjct: 1042 KYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGV 1101
Query: 1029 LHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRA 1088
L+Y+ + A ++++ M ERV+G +HP+ Q +LA C Q A L RA
Sbjct: 1102 LYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERA 1161
Query: 1089 RYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALS 1148
+ DHP +A ++ ++ + + D ++ E A+ + K GPK VA +
Sbjct: 1162 LDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATA 1221
Query: 1149 HHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTM 1208
+A +Y + AL + IY+ LG H + E+ + L L+ + ++
Sbjct: 1222 LVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAA 1281
Query: 1209 NEIYR 1213
E+Y+
Sbjct: 1282 -ELYK 1285
Score = 35.8 bits (81), Expect = 0.28
Identities = 25/99 (25%), Positives = 41/99 (41%)
Query: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
+ G L + L A+ + +G H L LA L+ M + EAL ++A+ +
Sbjct: 1189 KMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKI 1248
Query: 1050 SERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRA 1088
E +G HP + +LA+ + A L RA
Sbjct: 1249 YEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRA 1287
>gi|239756576 PREDICTED: cyclin Y-like 3 [Homo sapiens]
Length = 351
Score = 66.2 bits (160), Expect = 2e-10
Identities = 33/58 (56%), Positives = 40/58 (68%)
Query: 63 QVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDHFSELRSVEGLQEGSVLRVVE 120
+V PQE+ QEIHQVLMD CH TCF LH + + L+ F L S++GLQE SVL VE
Sbjct: 254 EVLPQEIKQEIHQVLMDHGVPCHYTCFLLHPEDSTLERFLVLHSIQGLQEDSVLCKVE 311
Score = 31.2 bits (69), Expect = 6.8
Identities = 16/33 (48%), Positives = 21/33 (63%)
Query: 270 PKPASPRFLSHSLVELLNQISPTFKKNFAVLQK 302
P+ F S SL ELLN+IS T + +FA +QK
Sbjct: 319 PQTYQSHFRSPSLAELLNRISGTCRNHFAGMQK 351
>gi|239748884 PREDICTED: cyclin Y-like 3 [Homo sapiens]
Length = 351
Score = 66.2 bits (160), Expect = 2e-10
Identities = 33/58 (56%), Positives = 40/58 (68%)
Query: 63 QVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDHFSELRSVEGLQEGSVLRVVE 120
+V PQE+ QEIHQVLMD CH TCF LH + + L+ F L S++GLQE SVL VE
Sbjct: 254 EVLPQEIKQEIHQVLMDHGVPCHYTCFLLHPEDSTLERFLVLHSIQGLQEDSVLCKVE 311
Score = 31.2 bits (69), Expect = 6.8
Identities = 16/33 (48%), Positives = 21/33 (63%)
Query: 270 PKPASPRFLSHSLVELLNQISPTFKKNFAVLQK 302
P+ F S SL ELLN+IS T + +FA +QK
Sbjct: 319 PQTYQSHFRSPSLAELLNRISGTCRNHFAGMQK 351
>gi|239745552 PREDICTED: cyclin Y-like 3 [Homo sapiens]
Length = 351
Score = 66.2 bits (160), Expect = 2e-10
Identities = 33/58 (56%), Positives = 40/58 (68%)
Query: 63 QVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDHFSELRSVEGLQEGSVLRVVE 120
+V PQE+ QEIHQVLMD CH TCF LH + + L+ F L S++GLQE SVL VE
Sbjct: 254 EVLPQEIKQEIHQVLMDHGVPCHYTCFLLHPEDSTLERFLVLHSIQGLQEDSVLCKVE 311
Score = 31.2 bits (69), Expect = 6.8
Identities = 16/33 (48%), Positives = 21/33 (63%)
Query: 270 PKPASPRFLSHSLVELLNQISPTFKKNFAVLQK 302
P+ F S SL ELLN+IS T + +FA +QK
Sbjct: 319 PQTYQSHFRSPSLAELLNRISGTCRNHFAGMQK 351
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 64.7 bits (156), Expect = 6e-10
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 7/196 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y +A + A+ +
Sbjct: 226 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIR 285
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G +HP +LA+ + A L RA + V G+DHP++A NN+
Sbjct: 286 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNL 345
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ +Y+ + + AL + GP VA + + +A Y + +F K
Sbjct: 346 ALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKF-------K 398
Query: 1171 EGYTIYKTQLGEDHEK 1186
+ T+YK L HE+
Sbjct: 399 QAETLYKEILTRAHER 414
Score = 50.4 bits (119), Expect = 1e-05
Identities = 47/205 (22%), Positives = 86/205 (41%), Gaps = 8/205 (3%)
Query: 1035 DYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLL 1094
D + + Q + + + G E P ++ +L + + + A+ L +A +
Sbjct: 186 DPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEK 245
Query: 1095 VFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVAR 1154
G DHP++A + N + LV +Y + L +ALA+ K G VA + + +A
Sbjct: 246 TSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAV 305
Query: 1155 VYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ-------AVALQRT 1207
+Y + +++ A K I + LG+DH + L L Q QR
Sbjct: 306 LYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRA 365
Query: 1208 MNEIYRNGSSANIPPLKFTAPSMAS 1232
+ EIY+ + P + T ++AS
Sbjct: 366 L-EIYQTKLGPDDPNVAKTKNNLAS 389
Score = 47.4 bits (111), Expect = 9e-05
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 5/167 (2%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ E+ G +HP+ LAL ++ A +LL A +
Sbjct: 227 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G+DHP +A NN+ ++ +Y + + AL + K G VA + +A
Sbjct: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
+ +++ ++ + + IY+T+LG D KTK +S YLK
Sbjct: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLK 393
Score = 32.3 bits (72), Expect = 3.1
Identities = 23/80 (28%), Positives = 35/80 (43%)
Query: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
++G KE L AL + V G H + L LA L G Y E Q+A+ +
Sbjct: 309 KRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEI 368
Query: 1050 SERVMGTEHPNTIQEYMHLA 1069
+ +G + PN + +LA
Sbjct: 369 YQTKLGPDDPNVAKTKNNLA 388
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 64.7 bits (156), Expect = 6e-10
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 7/196 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y +A + A+ +
Sbjct: 226 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIR 285
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G +HP +LA+ + A L RA + V G+DHP++A NN+
Sbjct: 286 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNL 345
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ +Y+ + + AL + GP VA + + +A Y + +F K
Sbjct: 346 ALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKF-------K 398
Query: 1171 EGYTIYKTQLGEDHEK 1186
+ T+YK L HE+
Sbjct: 399 QAETLYKEILTRAHER 414
Score = 50.4 bits (119), Expect = 1e-05
Identities = 47/205 (22%), Positives = 86/205 (41%), Gaps = 8/205 (3%)
Query: 1035 DYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLL 1094
D + + Q + + + G E P ++ +L + + + A+ L +A +
Sbjct: 186 DPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEK 245
Query: 1095 VFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVAR 1154
G DHP++A + N + LV +Y + L +ALA+ K G VA + + +A
Sbjct: 246 TSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAV 305
Query: 1155 VYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ-------AVALQRT 1207
+Y + +++ A K I + LG+DH + L L Q QR
Sbjct: 306 LYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRA 365
Query: 1208 MNEIYRNGSSANIPPLKFTAPSMAS 1232
+ EIY+ + P + T ++AS
Sbjct: 366 L-EIYQTKLGPDDPNVAKTKNNLAS 389
Score = 47.4 bits (111), Expect = 9e-05
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 5/167 (2%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ E+ G +HP+ LAL ++ A +LL A +
Sbjct: 227 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G+DHP +A NN+ ++ +Y + + AL + K G VA + +A
Sbjct: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
+ +++ ++ + + IY+T+LG D KTK +S YLK
Sbjct: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLK 393
Score = 32.3 bits (72), Expect = 3.1
Identities = 23/80 (28%), Positives = 35/80 (43%)
Query: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
++G KE L AL + V G H + L LA L G Y E Q+A+ +
Sbjct: 309 KRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEI 368
Query: 1050 SERVMGTEHPNTIQEYMHLA 1069
+ +G + PN + +LA
Sbjct: 369 YQTKLGPDDPNVAKTKNNLA 388
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 64.7 bits (156), Expect = 6e-10
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 7/196 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y +A + A+ +
Sbjct: 226 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIR 285
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G +HP +LA+ + A L RA + V G+DHP++A NN+
Sbjct: 286 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNL 345
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ +Y+ + + AL + GP VA + + +A Y + +F K
Sbjct: 346 ALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKF-------K 398
Query: 1171 EGYTIYKTQLGEDHEK 1186
+ T+YK L HE+
Sbjct: 399 QAETLYKEILTRAHER 414
Score = 50.4 bits (119), Expect = 1e-05
Identities = 47/205 (22%), Positives = 86/205 (41%), Gaps = 8/205 (3%)
Query: 1035 DYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLL 1094
D + + Q + + + G E P ++ +L + + + A+ L +A +
Sbjct: 186 DPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEK 245
Query: 1095 VFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVAR 1154
G DHP++A + N + LV +Y + L +ALA+ K G VA + + +A
Sbjct: 246 TSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAV 305
Query: 1155 VYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ-------AVALQRT 1207
+Y + +++ A K I + LG+DH + L L Q QR
Sbjct: 306 LYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRA 365
Query: 1208 MNEIYRNGSSANIPPLKFTAPSMAS 1232
+ EIY+ + P + T ++AS
Sbjct: 366 L-EIYQTKLGPDDPNVAKTKNNLAS 389
Score = 47.4 bits (111), Expect = 9e-05
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 5/167 (2%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ E+ G +HP+ LAL ++ A +LL A +
Sbjct: 227 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G+DHP +A NN+ ++ +Y + + AL + K G VA + +A
Sbjct: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
+ +++ ++ + + IY+T+LG D KTK +S YLK
Sbjct: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLK 393
Score = 32.3 bits (72), Expect = 3.1
Identities = 23/80 (28%), Positives = 35/80 (43%)
Query: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
++G KE L AL + V G H + L LA L G Y E Q+A+ +
Sbjct: 309 KRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEI 368
Query: 1050 SERVMGTEHPNTIQEYMHLA 1069
+ +G + PN + +LA
Sbjct: 369 YQTKLGPDDPNVAKTKNNLA 388
>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
Length = 637
Score = 62.0 bits (149), Expect = 4e-09
Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 7/194 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 242 QGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIR 301
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E +G +HP +LA+ + A L RA + V G +HP++A NN+
Sbjct: 302 ESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNL 361
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ +Y+ R+ + ALA+ GP VA + + +A Y + ++
Sbjct: 362 ALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKY-------A 414
Query: 1171 EGYTIYKTQLGEDH 1184
E T+YK L H
Sbjct: 415 EAETLYKEILTRAH 428
Score = 47.4 bits (111), Expect = 9e-05
Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)
Query: 1018 ETCACLRLLARL---HYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFA 1074
E A LR L L + G Y A+ ++A+ ER G HP+ LAL
Sbjct: 224 EIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD 283
Query: 1075 SSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVS 1134
++ A LL A + G DHP +A NN+ ++ +Y + + AL +
Sbjct: 284 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIR 343
Query: 1135 TKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDH-----EKTKE 1189
K G VA + +A + +++ ++ + ++ + IY+ QLG D+ K
Sbjct: 344 EKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 403
Query: 1190 SSEYLK 1195
+S YLK
Sbjct: 404 ASCYLK 409
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
++G KE L AL + V G H + L LA L G Y Q+A+ +
Sbjct: 325 KRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAI 384
Query: 1050 SERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYR 1087
E +G ++PN + +LA C+ LY+
Sbjct: 385 YEGQLGPDNPNVARTKNNLA-SCYLKQGKYAEAETLYK 421
>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 62.0 bits (149), Expect = 4e-09
Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 7/194 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 224 QGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIR 283
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E +G +HP +LA+ + A L RA + V G +HP++A NN+
Sbjct: 284 ESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNL 343
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ +Y+ R+ + ALA+ GP VA + + +A Y + ++
Sbjct: 344 ALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKY-------A 396
Query: 1171 EGYTIYKTQLGEDH 1184
E T+YK L H
Sbjct: 397 EAETLYKEILTRAH 410
Score = 47.4 bits (111), Expect = 9e-05
Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)
Query: 1018 ETCACLRLLARL---HYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFA 1074
E A LR L L + G Y A+ ++A+ ER G HP+ LAL
Sbjct: 206 EIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD 265
Query: 1075 SSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVS 1134
++ A LL A + G DHP +A NN+ ++ +Y + + AL +
Sbjct: 266 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIR 325
Query: 1135 TKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDH-----EKTKE 1189
K G VA + +A + +++ ++ + ++ + IY+ QLG D+ K
Sbjct: 326 EKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 385
Query: 1190 SSEYLK 1195
+S YLK
Sbjct: 386 ASCYLK 391
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
++G KE L AL + V G H + L LA L G Y Q+A+ +
Sbjct: 307 KRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAI 366
Query: 1050 SERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYR 1087
E +G ++PN + +LA C+ LY+
Sbjct: 367 YEGQLGPDNPNVARTKNNLA-SCYLKQGKYAEAETLYK 403
>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 62.0 bits (149), Expect = 4e-09
Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 7/194 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 224 QGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIR 283
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E +G +HP +LA+ + A L RA + V G +HP++A NN+
Sbjct: 284 ESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNL 343
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ +Y+ R+ + ALA+ GP VA + + +A Y + ++
Sbjct: 344 ALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKY-------A 396
Query: 1171 EGYTIYKTQLGEDH 1184
E T+YK L H
Sbjct: 397 EAETLYKEILTRAH 410
Score = 47.4 bits (111), Expect = 9e-05
Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)
Query: 1018 ETCACLRLLARL---HYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFA 1074
E A LR L L + G Y A+ ++A+ ER G HP+ LAL
Sbjct: 206 EIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD 265
Query: 1075 SSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVS 1134
++ A LL A + G DHP +A NN+ ++ +Y + + AL +
Sbjct: 266 QNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIR 325
Query: 1135 TKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDH-----EKTKE 1189
K G VA + +A + +++ ++ + ++ + IY+ QLG D+ K
Sbjct: 326 EKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 385
Query: 1190 SSEYLK 1195
+S YLK
Sbjct: 386 ASCYLK 391
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 990 QQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLM 1049
++G KE L AL + V G H + L LA L G Y Q+A+ +
Sbjct: 307 KRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAI 366
Query: 1050 SERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYR 1087
E +G ++PN + +LA C+ LY+
Sbjct: 367 YEGQLGPDNPNVARTKNNLA-SCYLKQGKYAEAETLYK 403
>gi|91825557 kinesin light chain 3 [Homo sapiens]
Length = 504
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/181 (25%), Positives = 77/181 (42%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 220 QGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIR 279
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G EHP +LA+ + A L RA + V G DHP++A NN+
Sbjct: 280 EQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNL 339
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ +++ R AL++ GP VA + + +A Y + +++ A + K
Sbjct: 340 ALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYK 399
Query: 1171 E 1171
E
Sbjct: 400 E 400
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 7/168 (4%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ ER G HP+ LAL ++ A LL+ A +
Sbjct: 221 GRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIRE 280
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G +HP +A NN+ ++ Y + + AL + K G VA + +A
Sbjct: 281 QTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLA 340
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDHE----KTKE--SSEYLK 1195
+ +++ +F +H +IY+ LG H+ KTK +S YLK
Sbjct: 341 LLCQNQGKFEDVERHYARALSIYEA-LGGPHDPNVAKTKNNLASAYLK 387
>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 55.1 bits (131), Expect = 4e-07
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 211 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 270
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G +HP +LA+ + A L RA + V G+ HP++A +N+
Sbjct: 271 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNL 330
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ + + + AL + GP VA + + +A Y + +++ A
Sbjct: 331 ALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA----- 385
Query: 1171 EGYTIYKTQLGEDHEK 1186
T+YK L HEK
Sbjct: 386 --ETLYKEILTRAHEK 399
Score = 49.3 bits (116), Expect = 2e-05
Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 25/268 (9%)
Query: 1055 GTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVL 1114
G E P ++ +L + + + A+ L +A + G DHP++A + N + LV
Sbjct: 191 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 250
Query: 1115 HGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYT 1174
+Y + L +ALA+ K G VA + + +A +Y + +++ A K
Sbjct: 251 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 310
Query: 1175 IYKTQLGEDHEKTKESSEYLKCLTQ------QAVALQRTMNEIYRNGSSANIPPLKFTAP 1228
I + LG+ H + L L Q + R EIY + P + T
Sbjct: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370
Query: 1229 SMASVLEQLNVINGILFIPLSQKDLENLKAEV-ARRHQLQEASRNRDR-------AEEPM 1280
++AS + +D E L E+ R H+ + S N D E
Sbjct: 371 NLASCYLKQG----------KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
Query: 1281 ATEPAPAGAP-GDLGSQPPAAKDPSPSV 1307
+ + AP G+ GS A K SP+V
Sbjct: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTV 448
Score = 42.7 bits (99), Expect = 0.002
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 5/167 (2%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ E+ G +HP+ LAL ++ A LL A +
Sbjct: 212 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRE 271
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G+DHP +A NN+ ++ +Y + + AL + K G VA +A
Sbjct: 272 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA 331
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
+ +++ + + + IY T+LG D KTK +S YLK
Sbjct: 332 LLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLK 378
>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 55.1 bits (131), Expect = 4e-07
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 211 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 270
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G +HP +LA+ + A L RA + V G+ HP++A +N+
Sbjct: 271 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNL 330
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ + + + AL + GP VA + + +A Y + +++ A
Sbjct: 331 ALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA----- 385
Query: 1171 EGYTIYKTQLGEDHEK 1186
T+YK L HEK
Sbjct: 386 --ETLYKEILTRAHEK 399
Score = 49.3 bits (116), Expect = 2e-05
Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 25/268 (9%)
Query: 1055 GTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVL 1114
G E P ++ +L + + + A+ L +A + G DHP++A + N + LV
Sbjct: 191 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 250
Query: 1115 HGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYT 1174
+Y + L +ALA+ K G VA + + +A +Y + +++ A K
Sbjct: 251 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 310
Query: 1175 IYKTQLGEDHEKTKESSEYLKCLTQ------QAVALQRTMNEIYRNGSSANIPPLKFTAP 1228
I + LG+ H + L L Q + R EIY + P + T
Sbjct: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370
Query: 1229 SMASVLEQLNVINGILFIPLSQKDLENLKAEV-ARRHQLQEASRNRDR-------AEEPM 1280
++AS + +D E L E+ R H+ + S N D E
Sbjct: 371 NLASCYLKQG----------KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
Query: 1281 ATEPAPAGAP-GDLGSQPPAAKDPSPSV 1307
+ + AP G+ GS A K SP+V
Sbjct: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTV 448
Score = 42.7 bits (99), Expect = 0.002
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 5/167 (2%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ E+ G +HP+ LAL ++ A LL A +
Sbjct: 212 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRE 271
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G+DHP +A NN+ ++ +Y + + AL + K G VA +A
Sbjct: 272 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA 331
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
+ +++ + + + IY T+LG D KTK +S YLK
Sbjct: 332 LLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLK 378
>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
Length = 545
Score = 55.1 bits (131), Expect = 4e-07
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 134 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 193
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G +HP +LA+ + A L RA + V G+ HP++A +N+
Sbjct: 194 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNL 253
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ + + + AL + GP VA + + +A Y + +++ A
Sbjct: 254 ALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA----- 308
Query: 1171 EGYTIYKTQLGEDHEK 1186
T+YK L HEK
Sbjct: 309 --ETLYKEILTRAHEK 322
Score = 49.3 bits (116), Expect = 2e-05
Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 25/268 (9%)
Query: 1055 GTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVL 1114
G E P ++ +L + + + A+ L +A + G DHP++A + N + LV
Sbjct: 114 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 173
Query: 1115 HGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYT 1174
+Y + L +ALA+ K G VA + + +A +Y + +++ A K
Sbjct: 174 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 233
Query: 1175 IYKTQLGEDHEKTKESSEYLKCLTQ------QAVALQRTMNEIYRNGSSANIPPLKFTAP 1228
I + LG+ H + L L Q + R EIY + P + T
Sbjct: 234 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 293
Query: 1229 SMASVLEQLNVINGILFIPLSQKDLENLKAEV-ARRHQLQEASRNRDR-------AEEPM 1280
++AS + +D E L E+ R H+ + S N D E
Sbjct: 294 NLASCYLKQG----------KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 343
Query: 1281 ATEPAPAGAP-GDLGSQPPAAKDPSPSV 1307
+ + AP G+ GS A K SP+V
Sbjct: 344 SKDKRRDSAPYGEYGSWYKACKVDSPTV 371
Score = 42.7 bits (99), Expect = 0.002
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 5/167 (2%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ E+ G +HP+ LAL ++ A LL A +
Sbjct: 135 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRE 194
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G+DHP +A NN+ ++ +Y + + AL + K G VA +A
Sbjct: 195 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA 254
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
+ +++ + + + IY T+LG D KTK +S YLK
Sbjct: 255 LLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLK 301
>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 55.1 bits (131), Expect = 4e-07
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 211 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 270
Query: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
E+ +G +HP +LA+ + A L RA + V G+ HP++A +N+
Sbjct: 271 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNL 330
Query: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
L+ + + + AL + GP VA + + +A Y + +++ A
Sbjct: 331 ALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA----- 385
Query: 1171 EGYTIYKTQLGEDHEK 1186
T+YK L HEK
Sbjct: 386 --ETLYKEILTRAHEK 399
Score = 49.3 bits (116), Expect = 2e-05
Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 25/268 (9%)
Query: 1055 GTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVL 1114
G E P ++ +L + + + A+ L +A + G DHP++A + N + LV
Sbjct: 191 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 250
Query: 1115 HGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYT 1174
+Y + L +ALA+ K G VA + + +A +Y + +++ A K
Sbjct: 251 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 310
Query: 1175 IYKTQLGEDHEKTKESSEYLKCLTQ------QAVALQRTMNEIYRNGSSANIPPLKFTAP 1228
I + LG+ H + L L Q + R EIY + P + T
Sbjct: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370
Query: 1229 SMASVLEQLNVINGILFIPLSQKDLENLKAEV-ARRHQLQEASRNRDR-------AEEPM 1280
++AS + +D E L E+ R H+ + S N D E
Sbjct: 371 NLASCYLKQG----------KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
Query: 1281 ATEPAPAGAP-GDLGSQPPAAKDPSPSV 1307
+ + AP G+ GS A K SP+V
Sbjct: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTV 448
Score = 42.7 bits (99), Expect = 0.002
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 5/167 (2%)
Query: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
G Y A+ ++A+ E+ G +HP+ LAL ++ A LL A +
Sbjct: 212 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRE 271
Query: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
G+DHP +A NN+ ++ +Y + + AL + K G VA +A
Sbjct: 272 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA 331
Query: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
+ +++ + + + IY T+LG D KTK +S YLK
Sbjct: 332 LLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLK 378
>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
sapiens]
Length = 585
Score = 44.3 bits (103), Expect = 8e-04
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 988 KVQQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAV 1047
+ +Q L+E +L +L L +G +V+T L RL+ M + EA KA+
Sbjct: 397 ETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAI 456
Query: 1048 LMSERVMGTEHPNTIQEYMHLA-LYCFASSQLSTALSLLYRARYLMLLVFGE-------D 1099
+ E+++G E HLA LY + +Q A L R+ + +FGE D
Sbjct: 457 QIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYD 516
Query: 1100 HPEMALLDNNIG 1111
+ + L N+IG
Sbjct: 517 YRGLIKLYNSIG 528
Score = 38.9 bits (89), Expect = 0.033
Identities = 52/195 (26%), Positives = 79/195 (40%), Gaps = 14/195 (7%)
Query: 1014 AMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCF 1073
A++ E CA L A+ HY EA +A M E G + + C
Sbjct: 207 ALYGELCALL--FAKSHY-----DEAYKWCIEA--MKEITAGLPVKVVVDVLRQASKACV 257
Query: 1074 ASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAV 1133
+ A L+ A YL FG HP+ + + G L V S+ + AL +
Sbjct: 258 VKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDI 317
Query: 1134 STKYHGPKALKVALSHHLVA---RVYE-SKAEFRSALQHEKEGYTIYKTQLGEDHEKTKE 1189
G K + VA +H +A V++ S +F +AL H + I L EDH
Sbjct: 318 RQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDH-LLLA 376
Query: 1190 SSEYLKCLTQQAVAL 1204
SS+ +K L + +A+
Sbjct: 377 SSKRVKALILEEIAI 391
Score = 34.3 bits (77), Expect = 0.80
Identities = 46/219 (21%), Positives = 96/219 (43%), Gaps = 16/219 (7%)
Query: 983 QSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSN 1042
Q+ +A V + K+ +LI A+ L + +G+ H + L + + ++++
Sbjct: 251 QASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAI 310
Query: 1043 QQKAVLMSERVMGTEHPNTIQEYMHLA----LYCFASSQLSTALSLLYRARYLMLLVFGE 1098
Q A+ + + V G ++ + + LA ++ ++S + AL RA ++ + E
Sbjct: 311 YQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPE 370
Query: 1099 DHPEMALLDNNIGLVLHGVM----EYDLSLRFLENA-------LAVSTKYHGPKALKVAL 1147
DH +A L+L + + R L+ A L ++ K G ++ A
Sbjct: 371 DHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAK 430
Query: 1148 SHHLVARVYESKAEFRSALQHEKEGYTIYKTQLG-EDHE 1185
+ + R+Y+S +F+ A + + I + LG ED+E
Sbjct: 431 HYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYE 469
>gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
Length = 501
Score = 39.7 bits (91), Expect = 0.019
Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 1016 HVETCACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFAS 1075
H+ CL AR ++A +KA+ +SE + G HP TI LA A
Sbjct: 354 HLLLGMCLDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQ 413
Query: 1076 SQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENAL 1131
+ A + RA L + +HPE+ ++ +N+ VL Y + + AL
Sbjct: 414 GRFDEAYIYMQRASDLARQI---NHPELHMVLSNLAAVLMHRERYTQAKEIYQEAL 466
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 9/73 (12%)
Query: 631 QNASQLETPSSLENG-GPSSLESKSEDPPGQEA---GSEEEGSSASGLAKVKELA----- 681
++ S+ ++ SS E+G G SS ES +ED E GSE E S G K K+
Sbjct: 696 ESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKG 755
Query: 682 ETIAADDGTDPRS 694
E ++D+G+D S
Sbjct: 756 EASSSDEGSDSSS 768
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 33.9 bits (76), Expect = 1.1
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 13/121 (10%)
Query: 1153 ARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIY 1212
A + + K + +S L+ EK + + K QL + E+ KE E L+ +A +L + ++E
Sbjct: 683 AEIQQLKRKLQS-LEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHL 741
Query: 1213 RNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASRN 1272
R + LE+ L QK++E LK E A+R L+E+
Sbjct: 742 RE------------TQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELA 789
Query: 1273 R 1273
R
Sbjct: 790 R 790
>gi|16579828 zinc finger protein 91 [Homo sapiens]
Length = 570
Score = 33.5 bits (75), Expect = 1.4
Identities = 20/42 (47%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Query: 1269 ASRNRDRAEEPMATEPAPAGAPGDL-GSQPPAAKDPSPSVQG 1309
A R +AE P +P+ P D+ G QP AAK PSP VQG
Sbjct: 67 AVSRRRKAEYPRRRRSSPSARPPDVPGQQPQAAKSPSP-VQG 107
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 1263 RHQLQEASRNRDRAEEPMA--TEPAPAGAPGDLGSQPPAAKDPSP 1305
R + E +R R A P A +P GAP D G +P ++P P
Sbjct: 82 RRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGP 126
>gi|20532340 angiopoietin 1 [Homo sapiens]
Length = 498
Score = 32.7 bits (73), Expect = 2.3
Identities = 42/167 (25%), Positives = 63/167 (37%), Gaps = 14/167 (8%)
Query: 229 NRKMHGDLMYLFVITAEDRQVSITASTRGFYLN--QSTAYHFNPKPASPRF--LSHS--- 281
NR HG Y F++ D ++T + N Q A H P +S + L H
Sbjct: 34 NRIQHGQCAYTFILPEHDGNCR-ESTTDQYNTNALQRDAPHVEPDFSSQKLQHLEHVMEN 92
Query: 282 ----LVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAE 337
L +L N I K A +Q+ VQ H + + S TA Q D
Sbjct: 93 YTQWLQKLENYIVENMKSEMAQIQQNAVQNHTATMLEIGTSLLSQTAEQTRKLTDVETQV 152
Query: 338 DAYTSRLGYE--EHIPGQTRDWNEELQTTRELPRKNLPERLLRERAI 382
TSRL + E+ + + LQ T E+ + + LL + +
Sbjct: 153 LNQTSRLEIQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKIL 199
>gi|110611908 mitogen-activated protein kinase kinase kinase kinase
1 isoform 1 [Homo sapiens]
Length = 821
Score = 32.7 bits (73), Expect = 2.3
Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 44/194 (22%)
Query: 199 LCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGF 258
L LQP D PL+ L ++T SG+ PP K + I +V++T S +
Sbjct: 208 LAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNFI-----KVTLTKSPK-- 260
Query: 259 YLNQSTAYHFNPKPASPRFLSHSLV-----------ELLNQI-SPTFKKNFAVLQKKRVQ 306
+P++ + LSH LV +LL+++ +P + ++ + +
Sbjct: 261 -----------KRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPE 309
Query: 307 RHPF--ERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTT 364
P RI + + S P A DC R + G E P T LQ
Sbjct: 310 LPPAIPRRIRSTHRSSSLGIPDA----DCCRRHMEFRKLRGMETRPPANT----ARLQPP 361
Query: 365 REL----PRKNLPE 374
R+L PRK L E
Sbjct: 362 RDLRSSSPRKQLSE 375
>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
isoform 2 [Homo sapiens]
Length = 833
Score = 32.7 bits (73), Expect = 2.3
Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 44/194 (22%)
Query: 199 LCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGF 258
L LQP D PL+ L ++T SG+ PP K + I +V++T S +
Sbjct: 208 LAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNFI-----KVTLTKSPK-- 260
Query: 259 YLNQSTAYHFNPKPASPRFLSHSLV-----------ELLNQI-SPTFKKNFAVLQKKRVQ 306
+P++ + LSH LV +LL+++ +P + ++ + +
Sbjct: 261 -----------KRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPE 309
Query: 307 RHPF--ERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTT 364
P RI + + S P A DC R + G E P T LQ
Sbjct: 310 LPPAIPRRIRSTHRSSSLGIPDA----DCCRRHMEFRKLRGMETRPPANT----ARLQPP 361
Query: 365 REL----PRKNLPE 374
R+L PRK L E
Sbjct: 362 RDLRSSSPRKQLSE 375
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 32.7 bits (73), Expect = 2.3
Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 26/141 (18%)
Query: 1148 SHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSE-YLKCLTQQAVAL-- 1204
SHHL ++ +KA+ R Q +E K +L D + + E ++ L Q+A AL
Sbjct: 253 SHHLALQLANAKAQLRRLRQELEE-----KAELLLDSQAEVQGLEAEIRRLRQEAQALSG 307
Query: 1205 QRTMNEIYRNGSSA------NIPPLK----------FTAPSMASVLEQLNVINGILFI-- 1246
Q E+YR + A +P L+ A + S LE+ V++G+L
Sbjct: 308 QAKRAELYREEAEALRERAGRLPRLQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASK 367
Query: 1247 PLSQKDLENLKAEVARRHQLQ 1267
L ++ LE + AR H+ Q
Sbjct: 368 ALLEEQLEAARERCARLHETQ 388
>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
sapiens]
Length = 614
Score = 32.3 bits (72), Expect = 3.1
Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 1241 NGILFIPLSQKDLENLKAEVARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAA 1300
+ + F + +++ + + AE+ L + N+ ++ P+ T P PG +G PP A
Sbjct: 201 DAVRFGRIPKREKQRMLAEMQSAMNL---ANNQLSSQCPLETSPTQHPTPGPMGPSPPPA 257
Query: 1301 KDPSPSV 1307
PSP V
Sbjct: 258 PVPSPLV 264
>gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]
Length = 1173
Score = 32.0 bits (71), Expect = 4.0
Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 20/139 (14%)
Query: 1185 EKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIP-------PLKFTAPSMASVLEQL 1237
++TK +L L+Q+ A+++ N + +N ++++ PL PS S L L
Sbjct: 432 KETKMQKPHLP-LSQEKSAIKKASN-LQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPL 489
Query: 1238 NVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDRAEEPMATEPAPAG--APGDLGS 1295
N N L P+S+KD E ++ H + +A+ A +G + G L S
Sbjct: 490 NAKNCAL--PVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRS 547
Query: 1296 Q-------PPAAKDPSPSV 1307
+ PPAA + P +
Sbjct: 548 EYGTPTKSPPAALEVVPCI 566
>gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]
Length = 1186
Score = 32.0 bits (71), Expect = 4.0
Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 20/139 (14%)
Query: 1185 EKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIP-------PLKFTAPSMASVLEQL 1237
++TK +L L+Q+ A+++ N + +N ++++ PL PS S L L
Sbjct: 432 KETKMQKPHLP-LSQEKSAIKKASN-LQKNKTASSTTKEKETKLPLLSRVPSAGSSLVPL 489
Query: 1238 NVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDRAEEPMATEPAPAG--APGDLGS 1295
N N L P+S+KD E ++ H + +A+ A +G + G L S
Sbjct: 490 NAKNCAL--PVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLRS 547
Query: 1296 Q-------PPAAKDPSPSV 1307
+ PPAA + P +
Sbjct: 548 EYGTPTKSPPAALEVVPCI 566
>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit 9A
[Homo sapiens]
Length = 1098
Score = 32.0 bits (71), Expect = 4.0
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 1126 FLENALAVSTKYHGPKALKVALSHHLV--ARVYESKAEFRSALQHEKEGYTIYKTQLGED 1183
F + L S H K L++ H V A + + K + ++A ++EK + + KTQL ++
Sbjct: 666 FSPSELDTSKLSHKFKELQIK---HAVTEAEIQKLKTKLQAA-ENEKVRWELEKTQLQQN 721
Query: 1184 HEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGI 1243
E+ KE L+ +A L T+NE LK T ++ ++ N
Sbjct: 722 IEENKERMLKLESYWIEAQTLCHTVNE-----------HLKETQSQYQALEKKYNKAKK- 769
Query: 1244 LFIPLSQKDLENLKAEVARRHQLQEASR 1271
L QK+L+ +K + A R ++++ +
Sbjct: 770 LIKDFQQKELDFIKRQEAERKKIEDLEK 797
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,489,846
Number of Sequences: 37866
Number of extensions: 2466021
Number of successful extensions: 9317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 9209
Number of HSP's gapped (non-prelim): 111
length of query: 1309
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1195
effective length of database: 13,930,794
effective search space: 16647298830
effective search space used: 16647298830
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.