Search of human proteins with 87159831

Search of human proteins with 87159831

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|87159831 N-6 adenine-specific DNA methyltransferase 1
isoform 2 [Homo sapiens]
         (186 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|87159831 N-6 adenine-specific DNA methyltransferase 1 isoform...   372   e-103
gi|87159829 N-6 adenine-specific DNA methyltransferase 1 isoform...   357   4e-99
gi|7705409 HemK methyltransferase family member 1 [Homo sapiens]       31   0.54 
gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]         29   2.0  
gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]         29   2.0  
gi|6466450 catechol-O-methyltransferase isoform S-COMT [Homo sap...    29   2.7  
gi|205830453 catechol-O-methyltransferase isoform MB-COMT [Homo ...    29   2.7  
gi|205830451 catechol-O-methyltransferase isoform MB-COMT [Homo ...    29   2.7  
gi|4502969 catechol-O-methyltransferase isoform MB-COMT [Homo sa...    29   2.7  
gi|4502509 complement component 5 receptor 1 [Homo sapiens]            28   3.5  
gi|226530908 protein-L-isoaspartate (D-aspartate) O-methyltransf...    28   3.5  
gi|222831587 tRNA methyltransferase 61 homolog B [Homo sapiens]        28   5.9  
gi|116284392 mucin 2 precursor [Homo sapiens]                          27   7.8  
gi|239753619 PREDICTED: hypothetical protein [Homo sapiens]            27   7.8  
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              27   7.8  
gi|239748204 PREDICTED: hypothetical protein XP_002346595 [Homo ...    27   7.8  
gi|239742102 PREDICTED: hypothetical protein XP_002342436 [Homo ...    27   7.8  
gi|25282469 retinol dehydrogenase 10 [Homo sapiens]                    27   7.8  

>gi|87159831 N-6 adenine-specific DNA methyltransferase 1 isoform 2
           [Homo sapiens]
          Length = 186

 Score =  372 bits (954), Expect = e-103
 Identities = 186/186 (100%), Positives = 186/186 (100%)

Query: 1   MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLNALEAAAAELAGVEICLEVGSGSGVVS 60
           MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLNALEAAAAELAGVEICLEVGSGSGVVS
Sbjct: 1   MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLNALEAAAAELAGVEICLEVGSGSGVVS 60

Query: 61  AFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVGSHGIEAAWAGGKNG 120
           AFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVGSHGIEAAWAGGKNG
Sbjct: 61  AFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVGSHGIEAAWAGGKNG 120

Query: 121 REVMDRFFPLVPDLLSPKGLFYLVTIKENNPEEILKIMKTKGLQGTTALSRQAGQETLSV 180
           REVMDRFFPLVPDLLSPKGLFYLVTIKENNPEEILKIMKTKGLQGTTALSRQAGQETLSV
Sbjct: 121 REVMDRFFPLVPDLLSPKGLFYLVTIKENNPEEILKIMKTKGLQGTTALSRQAGQETLSV 180

Query: 181 LKFTKS 186
           LKFTKS
Sbjct: 181 LKFTKS 186


>gi|87159829 N-6 adenine-specific DNA methyltransferase 1 isoform 1
           [Homo sapiens]
          Length = 214

 Score =  357 bits (915), Expect = 4e-99
 Identities = 186/214 (86%), Positives = 186/214 (86%), Gaps = 28/214 (13%)

Query: 1   MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLNALEAAAAELAGVEICLEVGSGSGVVS 60
           MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLNALEAAAAELAGVEICLEVGSGSGVVS
Sbjct: 1   MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLNALEAAAAELAGVEICLEVGSGSGVVS 60

Query: 61  AFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLV--------------- 105
           AFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLV               
Sbjct: 61  AFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVKGLLPRLTEKVDLLV 120

Query: 106 -------------GSHGIEAAWAGGKNGREVMDRFFPLVPDLLSPKGLFYLVTIKENNPE 152
                        GSHGIEAAWAGGKNGREVMDRFFPLVPDLLSPKGLFYLVTIKENNPE
Sbjct: 121 FNPPYVVTPPQEVGSHGIEAAWAGGKNGREVMDRFFPLVPDLLSPKGLFYLVTIKENNPE 180

Query: 153 EILKIMKTKGLQGTTALSRQAGQETLSVLKFTKS 186
           EILKIMKTKGLQGTTALSRQAGQETLSVLKFTKS
Sbjct: 181 EILKIMKTKGLQGTTALSRQAGQETLSVLKFTKS 214


>gi|7705409 HemK methyltransferase family member 1 [Homo sapiens]
          Length = 338

 Score = 31.2 bits (69), Expect = 0.54
 Identities = 34/154 (22%), Positives = 58/154 (37%), Gaps = 39/154 (25%)

Query: 45  GVEICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDL 104
           G  + LEVG GSG +S  L S + PQ+  +  D    A + T E A+  ++  +  I  L
Sbjct: 159 GSPLILEVGCGSGAISLSLLSQL-PQSRVIAVDKREAAISLTHENAQRLRLQDRIWIIHL 217

Query: 105 -------------------------------------VGSHGIEAAWAGGKNGREVMDRF 127
                                                + S+   AA  GG+ G +++   
Sbjct: 218 DMTSERSWTHLPWGPMDLIVSNPPYVFHQDMEQLAPEIRSYEDPAALDGGEEGMDIITHI 277

Query: 128 FPLVPDLLSPKGLFYLVTIKENNPEEILKIMKTK 161
             L P LL   G  +L  +   +PE +   ++++
Sbjct: 278 LALAPRLLKDSGSIFL-EVDPRHPELVSSWLQSR 310


>gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
          Length = 433

 Score = 29.3 bits (64), Expect = 2.0
 Identities = 11/27 (40%), Positives = 19/27 (70%)

Query: 47  EICLEVGSGSGVVSAFLASMIGPQALY 73
           ++ L+VG G+G++S F A    P+A+Y
Sbjct: 139 KVILDVGCGTGIISLFCAHYARPRAVY 165


>gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
          Length = 433

 Score = 29.3 bits (64), Expect = 2.0
 Identities = 11/27 (40%), Positives = 19/27 (70%)

Query: 47  EICLEVGSGSGVVSAFLASMIGPQALY 73
           ++ L+VG G+G++S F A    P+A+Y
Sbjct: 139 KVILDVGCGTGIISLFCAHYARPRAVY 165


>gi|6466450 catechol-O-methyltransferase isoform S-COMT [Homo
          sapiens]
          Length = 221

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 13/39 (33%), Positives = 23/39 (58%)

Query: 48 ICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACT 86
          + LE+G+  G  +  +A ++ P A  +  +INP+ AA T
Sbjct: 61 VLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAIT 99


>gi|205830453 catechol-O-methyltransferase isoform MB-COMT [Homo
           sapiens]
          Length = 271

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 13/39 (33%), Positives = 23/39 (58%)

Query: 48  ICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACT 86
           + LE+G+  G  +  +A ++ P A  +  +INP+ AA T
Sbjct: 111 VLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAIT 149


>gi|205830451 catechol-O-methyltransferase isoform MB-COMT [Homo
           sapiens]
          Length = 271

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 13/39 (33%), Positives = 23/39 (58%)

Query: 48  ICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACT 86
           + LE+G+  G  +  +A ++ P A  +  +INP+ AA T
Sbjct: 111 VLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAIT 149


>gi|4502969 catechol-O-methyltransferase isoform MB-COMT [Homo
           sapiens]
          Length = 271

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 13/39 (33%), Positives = 23/39 (58%)

Query: 48  ICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACT 86
           + LE+G+  G  +  +A ++ P A  +  +INP+ AA T
Sbjct: 111 VLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAIT 149


>gi|4502509 complement component 5 receptor 1 [Homo sapiens]
          Length = 350

 Score = 28.5 bits (62), Expect = 3.5
 Identities = 12/34 (35%), Positives = 17/34 (50%)

Query: 17  GAFSDVYEPAEDTFLLLNALEAAAAELAGVEICL 50
           G      EP+  TFLLLN L++     A +  C+
Sbjct: 262 GIMMSFLEPSSPTFLLLNKLDSLCVSFAYINCCI 295


>gi|226530908 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase 1 [Homo sapiens]
          Length = 285

 Score = 28.5 bits (62), Expect = 3.5
 Identities = 15/34 (44%), Positives = 21/34 (61%)

Query: 35  ALEAAAAELAGVEICLEVGSGSGVVSAFLASMIG 68
           ALE    +L      L+VGSGSG+++A  A M+G
Sbjct: 126 ALELLFDQLHEGAKALDVGSGSGILTACFARMVG 159


>gi|222831587 tRNA methyltransferase 61 homolog B [Homo sapiens]
          Length = 477

 Score = 27.7 bits (60), Expect = 5.9
 Identities = 12/32 (37%), Positives = 19/32 (59%)

Query: 50  LEVGSGSGVVSAFLASMIGPQALYMCTDINPE 81
           LE GSGSG +S FL+  +G Q   +  ++  +
Sbjct: 251 LEAGSGSGGMSLFLSKAVGSQGRVISFEVRKD 282


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 14/52 (26%), Positives = 22/52 (42%), Gaps = 8/52 (15%)

Query: 48   ICLEVGSGSGVVSAFLASMIGP------QALYMCTDINPEAAACTLETARCN 93
            +CLE   GSG++         P         Y+ T++NP    C +   +CN
Sbjct: 4839 VCLE--GGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 4888


>gi|239753619 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 170

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 3/88 (3%)

Query: 41  AELAGVEICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPV 100
           + LAG    LE G  S  V A +A  +  +  +   D     AAC++  +       + V
Sbjct: 46  SSLAGASSALEDGELS--VEALVALSVSAEPAFSSEDAGAWGAACSVAASPSPFFSSEGV 103

Query: 101 ITDLVGSHGIEAAWAGGKNGREVMDRFF 128
              L GS G+E   AG  +   V   FF
Sbjct: 104 SPALPGSSGLEPV-AGAASAVVVPSPFF 130


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 14/52 (26%), Positives = 22/52 (42%), Gaps = 8/52 (15%)

Query: 48   ICLEVGSGSGVVSAFLASMIGP------QALYMCTDINPEAAACTLETARCN 93
            +CLE   GSG++         P         Y+ T++NP    C +   +CN
Sbjct: 2299 VCLE--GGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348


>gi|239748204 PREDICTED: hypothetical protein XP_002346595 [Homo
           sapiens]
          Length = 170

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 3/88 (3%)

Query: 41  AELAGVEICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPV 100
           + LAG    LE G  S  V A +A  +  +  +   D     AAC++  +       + V
Sbjct: 46  SSLAGASSALEDGELS--VEALVALSVSAEPAFSSEDAGAWGAACSVAASPSPFFSSEGV 103

Query: 101 ITDLVGSHGIEAAWAGGKNGREVMDRFF 128
              L GS G+E   AG  +   V   FF
Sbjct: 104 SPALPGSSGLEPV-AGAASAVVVPSPFF 130


>gi|239742102 PREDICTED: hypothetical protein XP_002342436 [Homo
           sapiens]
          Length = 170

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 3/88 (3%)

Query: 41  AELAGVEICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPV 100
           + LAG    LE G  S  V A +A  +  +  +   D     AAC++  +       + V
Sbjct: 46  SSLAGASSALEDGELS--VEALVALSVSAEPAFSSEDAGAWGAACSVAASPSPFFSSEGV 103

Query: 101 ITDLVGSHGIEAAWAGGKNGREVMDRFF 128
              L GS G+E   AG  +   V   FF
Sbjct: 104 SPALPGSSGLEPV-AGAASAVVVPSPFF 130


>gi|25282469 retinol dehydrogenase 10 [Homo sapiens]
          Length = 341

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 10/63 (15%)

Query: 29 TFLLLNALEAAAAE---------LAGVEICLEVGSGSGVVSAFLASMIGPQALYMCTDIN 79
          TF +L A   AAA          +AG ++CL  G+GSG+   F       +AL +  DIN
Sbjct: 11 TFKVLWAFVLAAARWLVRPKEKSVAG-QVCLITGAGSGLGRLFALEFARRRALLVLWDIN 69

Query: 80 PEA 82
           ++
Sbjct: 70 TQS 72


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,946,880
Number of Sequences: 37866
Number of extensions: 294197
Number of successful extensions: 634
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 622
Number of HSP's gapped (non-prelim): 20
length of query: 186
length of database: 18,247,518
effective HSP length: 96
effective length of query: 90
effective length of database: 14,612,382
effective search space: 1315114380
effective search space used: 1315114380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.