Guide to the Human Genome
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Name: COMT Sequence: fasta or formatted (221aa) NCBI GI: 6466450
Description:

catechol-O-methyltransferase isoform S-COMT

Referenced in:

Catecholamines

Other entries for this name:
alt prot [271aa] catechol-O-methyltransferase isoform MB-COMT
alt prot [271aa] catechol-O-methyltransferase isoform MB-COMT
alt prot [271aa] catechol-O-methyltransferase isoform MB-COMT
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.1         18           2
 C cysteine            3.2          7           1
 D aspartate           7.7         17           1
 E glutamate           6.8         15           2
 F phenylalanine       2.3          5           1
 G glycine             7.7         17           1
 H histidine           2.7          6           1
 I isoleucine          5.4         12           2
 K lysine              6.3         14           3
 L leucine            10.9         24           3
 M methionine          2.3          5           1
 N asparagine          2.3          5           1
 P proline             4.5         10           1
 Q glutamine           4.5         10           1
 R arginine            4.1          9           1
 S serine              4.1          9           2
 T threonine           4.1          9           1
 V valine              8.6         19           2
 W tryptophan          0.9          2           1
 Y tyrosine            3.6          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   catechol-O-methyltransferase isoform S-COMT 
COMT                  1.000   catechol-O-methyltransferase isoform MB-COMT 
COMT                  1.000   catechol-O-methyltransferase isoform MB-COMT 
COMT                  1.000   catechol-O-methyltransferase isoform MB-COMT 
LRTOMT                0.317   leucine rich transmembrane and 0-methyltransferase ...
LRTOMT                0.317   leucine rich transmembrane and 0-methyltransferase ...
LRTOMT                0.317   leucine rich transmembrane and 0-methyltransferase ...
COMTD1                0.035   catechol-O-methyltransferase domain containing 1 [Ho...
N6AMT1                0.012   N-6 adenine-specific DNA methyltransferase 1 isoform...
LARP6                 0.012   La ribonucleoprotein domain family, member 6 isoform...
TGS1                  0.012   trimethylguanosine synthase homolog 
N6AMT1                0.009   N-6 adenine-specific DNA methyltransferase 1 isoform...
LOC653125             0.007   PREDICTED: similar to Golgin subfamily A member 8-l...
FLJ32682              0.007   hypothetical protein LOC220081 
A2ML1                 0.007   alpha-2-macroglobulin-like 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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