Guide to the Human Genome
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Search of human proteins with 8394376

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8394376 syntaxin 18 [Homo sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8394376 syntaxin 18 [Homo sapiens]                                 661   0.0  
gi|210032790 hypothetical protein LOC27146 [Homo sapiens]              43   5e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    41   0.001
gi|16418379 syntaxin 1B [Homo sapiens]                                 40   0.002
gi|148746195 trichohyalin [Homo sapiens]                               40   0.002
gi|212276096 leucine rich repeat (in FLII) interacting protein 1...    39   0.005
gi|157168329 formin 1 [Homo sapiens]                                   39   0.007
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap...    39   0.007
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap...    39   0.007
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap...    39   0.007
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap...    39   0.007
gi|40538794 coiled-coil domain containing 21 [Homo sapiens]            39   0.007
gi|62243374 MAD1-like 1 protein [Homo sapiens]                         39   0.009
gi|62243369 MAD1-like 1 protein [Homo sapiens]                         39   0.009
gi|62243332 MAD1-like 1 protein [Homo sapiens]                         39   0.009
gi|94400932 syntaxin 5 [Homo sapiens]                                  39   0.009
gi|56550043 sarcolemma associated protein [Homo sapiens]               39   0.009
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    38   0.011
gi|170932494 syntaxin 7 [Homo sapiens]                                 38   0.011
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    38   0.011
gi|100814339 coiled-coil domain containing 146 [Homo sapiens]          38   0.011
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    38   0.015
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]                        38   0.015
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa...    37   0.019
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa...    37   0.019
gi|52856430 protein expressed in prostate, ovary, testis, and pl...    37   0.025
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ...    37   0.025
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              37   0.025
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    37   0.032
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    37   0.032

>gi|8394376 syntaxin 18 [Homo sapiens]
          Length = 335

 Score =  661 bits (1705), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MAVDITLLFRASVKTVKTRNKALGVAVGGGVDGSRDELFRRSPRPKGDFSSRAREVISHI 60
           MAVDITLLFRASVKTVKTRNKALGVAVGGGVDGSRDELFRRSPRPKGDFSSRAREVISHI
Sbjct: 1   MAVDITLLFRASVKTVKTRNKALGVAVGGGVDGSRDELFRRSPRPKGDFSSRAREVISHI 60

Query: 61  GKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHK 120
           GKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHK
Sbjct: 61  GKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHK 120

Query: 121 EIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRES 180
           EIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRES
Sbjct: 121 EIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRES 180

Query: 181 TSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ 240
           TSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ
Sbjct: 181 TSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ 240

Query: 241 RLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNE 300
           RLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNE
Sbjct: 241 RLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNE 300

Query: 301 DIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS 335
           DIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS
Sbjct: 301 DIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS 335


>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
          Length = 1060

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 48/244 (19%), Positives = 107/244 (43%), Gaps = 37/244 (15%)

Query: 63  LRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEI 122
           L+D L++  +D +  ++  +       + ER ++ ++ +         ++++R ++ KEI
Sbjct: 424 LKDQLVKRLEDLVKKHTVEIKSVRSSVEAERKKLQREVEA-------QLEEVRKKSEKEI 476

Query: 123 HSQQVKEHRTAVLDFIEDYLKRVCKL--YSEQRAIRVKRVVDKKRLSKLEPEPNTKTRES 180
             +Q++E + A+   +++ L  V +L  + +Q         +K R +  E  P    R+ 
Sbjct: 477 --KQLEEEKAALNVKLQNSLLEVLRLEEFIQQ---------NKTRPTGAEESPQELGRQH 525

Query: 181 TSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ 240
            S  +      K  E +P  EE  +K+ AE         +G   DE   E  ++  +E  
Sbjct: 526 CSILETQDPCLKLDETSPRGEEYQDKLAAE---------EGTSSDE--EERTKVLLKEGS 574

Query: 241 RLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNE 300
                + SL  E      +  +I RL+E +  +  + +A++  + Q +   T N +E  +
Sbjct: 575 DPQPPLGSLLKE------KTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYREDLQ 628

Query: 301 DIRE 304
            +++
Sbjct: 629 ALKQ 632



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 43/169 (25%), Positives = 70/169 (41%), Gaps = 12/169 (7%)

Query: 113 QLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPE 172
           +L  +A +E   Q+++E R  +       L+ + +  SEQ+A        +K L  L+ E
Sbjct: 701 RLELQALEEKARQELQEERERMQAQQALLLESLRQELSEQQAACSGH---QKDLEALQAE 757

Query: 173 PNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEI 232
                R+  SS    Q P    +   ATEER     A + P  G  G G GE     EE 
Sbjct: 758 LRALGRQQASS----QCPGDSKDHIIATEERGGPGQAGSPP--GAAGQGSGEGCGLWEEN 811

Query: 233 QMFEQENQRLIGEMNSLFDEVRQIEGR---VVEISRLQEIFTEKVLQQE 278
              +   +RL  E+     E +++  +   + E  + Q     + L+QE
Sbjct: 812 AQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQE 860


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 45/197 (22%), Positives = 82/197 (41%), Gaps = 27/197 (13%)

Query: 117 EAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSK-LEPEPNT 175
           +AHKE+    +            +Y+K +  L +E  A+R K   DK  L K LE   NT
Sbjct: 115 DAHKELEQSHI------------NYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNT 162

Query: 176 KTR-------ESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELS 228
           +         ++ S + V +   +  +  P  EE+    +   Q +L    D K E    
Sbjct: 163 QLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQ----ILYLQKQLDATTDEKKETVTQ 218

Query: 229 PEEIQMFEQENQRLIGEMNSLFDEVRQIEG-RVVEISRLQEIFTEKVLQQEAEIDSIHQL 287
            + I   E  +Q     +NSL +E+ Q++     E+  L         + EAEI+ +++L
Sbjct: 219 LQNI--IEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNEL 276

Query: 288 VVGATENIKEGNEDIRE 304
                +  +   ++I++
Sbjct: 277 KENLVKQCEASEKNIQK 293



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 45/209 (21%), Positives = 91/209 (43%), Gaps = 30/209 (14%)

Query: 99   DAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVK 158
            + QI     ++A+     EA K    Q++KEH T V               +E   ++V+
Sbjct: 1086 EVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTV---------------NELEELQVQ 1130

Query: 159  RVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTW 218
               +KK+L K   E     +++  +  ++   +             E+++ E   +L T 
Sbjct: 1131 LQKEKKQLQKTMQELELVKKDAQQTTLMNMEIAD-----------YERLMKELNQKL-TN 1178

Query: 219  GDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQE 278
             + K ED    +EI++ +Q+ + L  E+ SL   V+Q E +  +I +L  + T+K L   
Sbjct: 1179 KNNKIED--LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLL-VKTKKELADS 1235

Query: 279  AEIDSIHQLVVGATENIKEGNEDIREAIK 307
             + ++ H ++  + +   E ++   E  K
Sbjct: 1236 KQAETDHLILQASLKGELEASQQQVEVYK 1264



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 40/214 (18%), Positives = 90/214 (42%), Gaps = 27/214 (12%)

Query: 120 KEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIR--VKRVVDKKRLSKLEPEPNTKT 177
           KE H +++ E       F+ D  K    L  E + ++   + +  +K+ + L  E   + 
Sbjct: 430 KEQHQKEISELNET---FLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREI 486

Query: 178 RESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGK--------------- 222
            E   +E + +S  K S+E  + +++    + E Q +L T    K               
Sbjct: 487 MEILQTE-LGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENE 545

Query: 223 ---GEDELSPE---EIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQ 276
               + EL PE    I+  +++N   +  ++     ++++EG++  ++  ++ F  K+  
Sbjct: 546 KLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKN 605

Query: 277 QEAEIDSIHQLVVGATENIKEGNEDIREAIKNNA 310
              E+D+ H+        I E  + + + I+ N+
Sbjct: 606 SHEEMDNFHKKCEREERLILELGKKVEQTIQYNS 639


>gi|16418379 syntaxin 1B [Homo sapiens]
          Length = 288

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 53/265 (20%), Positives = 111/265 (41%), Gaps = 37/265 (13%)

Query: 89  TDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHS-QQVKEHRTAVL------------ 135
           +D E + +  D   FM    E ++++R    K     +QVK+  +A+L            
Sbjct: 14  SDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE 73

Query: 136 --DFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNT-KTRESTSSEKVSQSPSK 192
             D   D  K   K+ S+ +AI  + +  ++ L++   +    KT+ ST S K  +  + 
Sbjct: 74  LEDLTADIKKTANKVRSKLKAIE-QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMT- 131

Query: 193 DSEENPATEERPEKILAETQPELGTWGDGKGEDELSP-----------EEIQMFEQENQR 241
             E N    +  ++     Q +L   G     +EL             ++I+M  Q  ++
Sbjct: 132 --EYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQ 189

Query: 242 LIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAE---IDSIHQLVVGATENIKEG 298
            + E+ +  +E+ ++E     I  L ++F +  +  E++   ID I   V  + + ++  
Sbjct: 190 ALNEIETRHNEIIKLE---TSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERA 246

Query: 299 NEDIREAIKNNAGFRVWILFFLVMC 323
             D ++A+K  +  R   +  ++ C
Sbjct: 247 VSDTKKAVKYQSKARRKKIMIIICC 271


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 24/204 (11%)

Query: 93   RDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLD----FIEDYLKRVCKL 148
            ++Q+ ++ Q+      E  ++ R +  ++   +Q +E      +      E+  KR  + 
Sbjct: 896  QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR--RR 953

Query: 149  YSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKIL 208
               +R  R  + + +K    L  EP  + R+    +   +   +  EE    EER ++  
Sbjct: 954  QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013

Query: 209  AETQPELGTWGDGKGEDELSPEEIQMFE--------QENQRLIGEMNSLFDEVRQIEGRV 260
             E + +       + +DEL  EE Q+          QE +R   E   L  E  Q+ G  
Sbjct: 1014 QEWERQY------RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067

Query: 261  VEISRLQEI----FTEKVLQQEAE 280
             E  R QE+      E+ LQQE E
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEE 1091



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 50/192 (26%), Positives = 90/192 (46%), Gaps = 19/192 (9%)

Query: 112 QQLRTEAHKEIHSQQVKEHR-----TAVLDFIEDYLKR---VCKLYSEQRAIRVKRVVDK 163
           QQLR E  +E H Q+ ++ R         +   D+LKR     +   E+R  ++KR  ++
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482

Query: 164 KRLS---KLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKI--LAETQPELGTW 218
           +R     KLE E   + +E    +++ +   +  E+    +E  E++     ++ +L   
Sbjct: 483 ERRERWLKLEEEERREQQE-RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541

Query: 219 GDGKGEDELSPEEIQMFEQE--NQRLIGEMNSLFDEV--RQIEGRVVEISRLQEIFTEKV 274
            + + E  L  EE +  EQE   QRL  E     D++  R+ E R   + R QE   E+ 
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601

Query: 275 LQQEAEIDSIHQ 286
           L++E E++ + Q
Sbjct: 602 LKRE-EVERLEQ 612



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 38/199 (19%), Positives = 86/199 (43%), Gaps = 11/199 (5%)

Query: 90  DTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKE-HRTAVLDFIEDYLKRVCKL 148
           + ++ + ++  ++F     +  ++  T   KE    Q +E  R   L   E+ L+++   
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL--- 281

Query: 149 YSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKIL 208
             E++ +R +R  ++++  +L  E   + ++     +  +   +  E     EER E+ L
Sbjct: 282 --ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339

Query: 209 AETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQE 268
              Q E       + ++E   E+    EQE +R   ++        Q   R  ++ R Q+
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR-----EQQLRREQQLRREQQ 394

Query: 269 IFTEKVLQQEAEIDSIHQL 287
           +  E+ L++E ++    QL
Sbjct: 395 LRREQQLRREQQLRREQQL 413



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 42/207 (20%), Positives = 79/207 (38%), Gaps = 22/207 (10%)

Query: 35  RDELFRRSPRPKGDFSSRAREVISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERD 94
           R++L +R    + +   R + +     + RD LL+  ++             R    +R+
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER------------RQQRLKRE 593

Query: 95  QIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRA 154
           Q ++  Q   R   E ++Q      +    +  +E R  +L   E   +R  +L  EQ+ 
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653

Query: 155 IRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPE 214
            R      ++RL + E E   + R     E+  +      EE     ER +  + + Q +
Sbjct: 654 RR------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQ 707

Query: 215 LGTWGDGKGEDELSPEEIQMFEQENQR 241
           L +  D +     S       +QE QR
Sbjct: 708 LESEADARQSKVYSRPR----KQEGQR 730



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 34/180 (18%), Positives = 77/180 (42%), Gaps = 16/180 (8%)

Query: 92   ERDQIDQDAQIFMRTCSEA--IQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLY 149
            ++D++ Q+ +  +R   E   +Q+   +  +E   QQ +E         E   +R  +L 
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE----ERETRRRQEL- 1076

Query: 150  SEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILA 209
              +R  R +  + ++    L  EP  + R+    +   +   +  EE    EER ++   
Sbjct: 1077 --ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134

Query: 210  ETQPELGTWGDGKGEDELSPEEIQMFEQE-NQRLIGEMNSLFDEVRQIEGRVVEISRLQE 268
            E + +       + E+E+  EE Q+  +E  +R   E+   + E  +++    ++ R ++
Sbjct: 1135 ELERQY------REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ 1188


>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
           isoform 3 [Homo sapiens]
          Length = 808

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 35/154 (22%), Positives = 74/154 (48%), Gaps = 25/154 (16%)

Query: 150 SEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEK--- 206
           +E R IR+K + ++++  +     + ++R +TS+    +  S  S  +   EERPEK   
Sbjct: 35  AEAREIRMKEL-ERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFT 93

Query: 207 ---------ILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIE 257
                    + A T   LG     +G  + S   I +  + + R I E+N L D+++ +E
Sbjct: 94  EKGSRNMPGLSAATLASLGGTSSRRGSGDTS---ISIDTEASIREIKELNELKDQIQDVE 150

Query: 258 GRVVE--------ISRLQEIFTEKVLQQEAEIDS 283
           G+ ++        ++ ++E + +K +   A++D+
Sbjct: 151 GKYMQGLKEMKDSLAEVEEKY-KKAMVSNAQLDN 183


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 42/151 (27%), Positives = 58/151 (38%), Gaps = 25/151 (16%)

Query: 170 EPEPNTKTRESTSSEKVSQSPSKDSEENPA----------------TEERPEKILAETQP 213
           EPE  + T    S   V   PS++S+ENP                   E P++I  E   
Sbjct: 156 EPEEGSSTNGPKSPSGVLSEPSQESKENPGGFRENTVTGEMNGAELCAEDPQRIPPEMSS 215

Query: 214 ELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEK 273
           +L   G+G  + E  P + Q+ E+ +Q L    N          G     S  +E+  EK
Sbjct: 216 KLEA-GNGGLQTERRPSQDQVGEEGSQDLPAVTNQ-----NSSVGITESASSKKEVSGEK 269

Query: 274 VLQQEAEIDSIHQLVVGATENIKEGNEDIRE 304
             Q  A    +  L  GAT    EG E I E
Sbjct: 270 SFQLPAFFSGLRVLKKGAT---AEGGETITE 297


>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
           sapiens]
          Length = 436

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 52/255 (20%), Positives = 109/255 (42%), Gaps = 11/255 (4%)

Query: 56  VISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLR 115
           VI H+   R+  L+  K       +   E   +T +   +  + A+  ++T  EA  Q +
Sbjct: 105 VIQHLLSEREEALKQHKTLSQELVNLRGEL--VTASTTCEKLEKARNELQTVYEAFVQ-Q 161

Query: 116 TEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNT 175
            +A K     ++KE  T   + + D      + Y  Q   +   +      SKLE E + 
Sbjct: 162 HQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASH 221

Query: 176 KTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTW-GDGKGEDELSPEEIQM 234
             +     +    S S+  + +   ++  E +L+E Q  L     D K E++   E+++ 
Sbjct: 222 SEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKS 281

Query: 235 FEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLV------ 288
            E++ +R   + N    ++  +E  +  +  + EI  EK+ QQ+ ++  + +LV      
Sbjct: 282 -EEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 340

Query: 289 VGATENIKEGNEDIR 303
           V   +  ++ NE+++
Sbjct: 341 VDKLKRFQQENEELK 355


>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
          Length = 1270

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 52/255 (20%), Positives = 109/255 (42%), Gaps = 11/255 (4%)

Query: 56   VISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLR 115
            VI H+   R+  L+  K       +   E   +T +   +  + A+  ++T  EA  Q +
Sbjct: 939  VIQHLLSEREEALKQHKTLSQELVNLRGEL--VTASTTCEKLEKARNELQTVYEAFVQ-Q 995

Query: 116  TEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNT 175
             +A K     ++KE  T   + + D      + Y  Q   +   +      SKLE E + 
Sbjct: 996  HQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASH 1055

Query: 176  KTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTW-GDGKGEDELSPEEIQM 234
              +     +    S S+  + +   ++  E +L+E Q  L     D K E++   E+++ 
Sbjct: 1056 SEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKS 1115

Query: 235  FEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLV------ 288
             E++ +R   + N    ++  +E  +  +  + EI  EK+ QQ+ ++  + +LV      
Sbjct: 1116 -EEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 1174

Query: 289  VGATENIKEGNEDIR 303
            V   +  ++ NE+++
Sbjct: 1175 VDKLKRFQQENEELK 1189


>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
          Length = 1216

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 52/255 (20%), Positives = 109/255 (42%), Gaps = 11/255 (4%)

Query: 56   VISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLR 115
            VI H+   R+  L+  K       +   E   +T +   +  + A+  ++T  EA  Q +
Sbjct: 885  VIQHLLSEREEALKQHKTLSQELVNLRGEL--VTASTTCEKLEKARNELQTVYEAFVQ-Q 941

Query: 116  TEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNT 175
             +A K     ++KE  T   + + D      + Y  Q   +   +      SKLE E + 
Sbjct: 942  HQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASH 1001

Query: 176  KTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTW-GDGKGEDELSPEEIQM 234
              +     +    S S+  + +   ++  E +L+E Q  L     D K E++   E+++ 
Sbjct: 1002 SEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKS 1061

Query: 235  FEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLV------ 288
             E++ +R   + N    ++  +E  +  +  + EI  EK+ QQ+ ++  + +LV      
Sbjct: 1062 -EEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 1120

Query: 289  VGATENIKEGNEDIR 303
            V   +  ++ NE+++
Sbjct: 1121 VDKLKRFQQENEELK 1135


>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
           sapiens]
          Length = 517

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 52/255 (20%), Positives = 109/255 (42%), Gaps = 11/255 (4%)

Query: 56  VISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLR 115
           VI H+   R+  L+  K       +   E   +T +   +  + A+  ++T  EA  Q +
Sbjct: 186 VIQHLLSEREEALKQHKTLSQELVNLRGEL--VTASTTCEKLEKARNELQTVYEAFVQ-Q 242

Query: 116 TEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNT 175
            +A K     ++KE  T   + + D      + Y  Q   +   +      SKLE E + 
Sbjct: 243 HQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASH 302

Query: 176 KTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTW-GDGKGEDELSPEEIQM 234
             +     +    S S+  + +   ++  E +L+E Q  L     D K E++   E+++ 
Sbjct: 303 SEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKS 362

Query: 235 FEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLV------ 288
            E++ +R   + N    ++  +E  +  +  + EI  EK+ QQ+ ++  + +LV      
Sbjct: 363 -EEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 421

Query: 289 VGATENIKEGNEDIR 303
           V   +  ++ NE+++
Sbjct: 422 VDKLKRFQQENEELK 436


>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
          Length = 762

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 63/254 (24%), Positives = 118/254 (46%), Gaps = 37/254 (14%)

Query: 83  SEYGRMTDT-ERDQIDQDAQIFMRTCSEAIQQLRTEAHK---EIHSQQVK--EHRTAVLD 136
           +++ + T+   R++ID + ++   + SE   QL  E+ K   + HS++VK  E R    D
Sbjct: 396 AQFAQKTEALSREKIDLEKKL---SASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRD 452

Query: 137 FIEDYLKRVCKLYSEQRAIRVKRVVDKKR----LSKLEPEPNTKTRESTSSEKVSQSPSK 192
              + LK+ C+  SEQ   + +R+   +R    L  LE       +   S  K ++   K
Sbjct: 453 KHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEK 512

Query: 193 DSEENPATEE-----RPEKI----LAETQPELGTWG----DGKGEDELSPE--EIQMFEQ 237
            +E     EE     R ++I    L + + E  + G    D +  +E S E  E++M   
Sbjct: 513 VTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESW 572

Query: 238 EN-----QRLIGEMNSLFDEVR-QIEGRVVEISRLQEIFTEKVLQQEAE-IDSIHQLVVG 290
           +      Q+++ +     D++R Q++    E++  QE  T + L++EA+  DS  Q +  
Sbjct: 573 QKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVA--QEEGTSQALREEAQRRDSALQQLRT 630

Query: 291 ATENIKEGNEDIRE 304
           A + +   N+D+ E
Sbjct: 631 AVKELSVQNQDLIE 644


>gi|62243374 MAD1-like 1 protein [Homo sapiens]
          Length = 718

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/226 (18%), Positives = 91/226 (40%), Gaps = 35/226 (15%)

Query: 90  DTERDQIDQDAQIFMRTCSEAIQQLRT-EAHKEI---HSQQVKEHRTAVLDFIEDYLKRV 145
           ++E+ ++ +   +  + C EA Q+++  +A +E    H QQ+K+            L++ 
Sbjct: 184 ESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKD------------LEQK 231

Query: 146 CKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPE 205
             L  +  AI      +  RL +LE E      ES    ++ ++     EE    + +  
Sbjct: 232 LSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRK-- 289

Query: 206 KILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISR 265
                            G  E   E +   E EN+RL+ ++ S ++ + Q  G  +    
Sbjct: 290 ----------------LGRQEKMQETLVGLELENERLLAKLQS-WERLDQTMGLSIRTPE 332

Query: 266 LQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKNNAG 311
               F  ++ Q+E  +   +  V  +   +++  + ++E ++  +G
Sbjct: 333 DLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSG 378


>gi|62243369 MAD1-like 1 protein [Homo sapiens]
          Length = 718

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/226 (18%), Positives = 91/226 (40%), Gaps = 35/226 (15%)

Query: 90  DTERDQIDQDAQIFMRTCSEAIQQLRT-EAHKEI---HSQQVKEHRTAVLDFIEDYLKRV 145
           ++E+ ++ +   +  + C EA Q+++  +A +E    H QQ+K+            L++ 
Sbjct: 184 ESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKD------------LEQK 231

Query: 146 CKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPE 205
             L  +  AI      +  RL +LE E      ES    ++ ++     EE    + +  
Sbjct: 232 LSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRK-- 289

Query: 206 KILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISR 265
                            G  E   E +   E EN+RL+ ++ S ++ + Q  G  +    
Sbjct: 290 ----------------LGRQEKMQETLVGLELENERLLAKLQS-WERLDQTMGLSIRTPE 332

Query: 266 LQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKNNAG 311
               F  ++ Q+E  +   +  V  +   +++  + ++E ++  +G
Sbjct: 333 DLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSG 378


>gi|62243332 MAD1-like 1 protein [Homo sapiens]
          Length = 718

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/226 (18%), Positives = 91/226 (40%), Gaps = 35/226 (15%)

Query: 90  DTERDQIDQDAQIFMRTCSEAIQQLRT-EAHKEI---HSQQVKEHRTAVLDFIEDYLKRV 145
           ++E+ ++ +   +  + C EA Q+++  +A +E    H QQ+K+            L++ 
Sbjct: 184 ESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKD------------LEQK 231

Query: 146 CKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPE 205
             L  +  AI      +  RL +LE E      ES    ++ ++     EE    + +  
Sbjct: 232 LSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRK-- 289

Query: 206 KILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISR 265
                            G  E   E +   E EN+RL+ ++ S ++ + Q  G  +    
Sbjct: 290 ----------------LGRQEKMQETLVGLELENERLLAKLQS-WERLDQTMGLSIRTPE 332

Query: 266 LQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKNNAG 311
               F  ++ Q+E  +   +  V  +   +++  + ++E ++  +G
Sbjct: 333 DLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSG 378


>gi|94400932 syntaxin 5 [Homo sapiens]
          Length = 355

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 23/108 (21%), Positives = 57/108 (52%), Gaps = 7/108 (6%)

Query: 225 DELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSI 284
           D  + +++Q+ ++++  +     S  D ++ IE  +VE+  + +     V +QE  I  I
Sbjct: 249 DSRTSQQLQLIDEQDSYI----QSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRI 304

Query: 285 HQLVVGATENIKEGNEDIREAIKNNAGFRVWIL--FFLVMCSFSLLFL 330
            + V+GA  +++  + +I +  ++    R W++   FL++  F ++F+
Sbjct: 305 DENVLGAQLDVEAAHSEILKYFQSVTSNR-WLMVKIFLILIVFFIIFV 351


>gi|56550043 sarcolemma associated protein [Homo sapiens]
          Length = 811

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 47/220 (21%), Positives = 93/220 (42%), Gaps = 28/220 (12%)

Query: 108 SEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRL- 166
           S+ + QL     + +H +Q+ E + A L       +R+  +  E      + ++D+ RL 
Sbjct: 162 SQELFQLSQYLQEALHREQMLEQKLATL-------QRLLAITQEASDTSWQALIDEDRLL 214

Query: 167 SKLEPEPN-------TKTRESTSSEKVSQSPSKDSEENPATEER----PEKI-----LAE 210
           S+LE   N        +T +S   E ++    K + E  A E       EKI     L+E
Sbjct: 215 SRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSE 274

Query: 211 TQPELGTWGDG----KGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRL 266
            +  L    D     K  +E + EE++    +    + E+  L D+++  EG+  EI + 
Sbjct: 275 VERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQK 334

Query: 267 QEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAI 306
            +   +++  +  E++   Q +    E ++  N+   E +
Sbjct: 335 GQAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERL 374



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 43/216 (19%), Positives = 87/216 (40%), Gaps = 22/216 (10%)

Query: 98  QDAQIFMRTCSEAIQQLRTEAHKEIHSQQV-KEHRTAVLDFIEDYLKRVCKLYSEQRAIR 156
           Q+ Q   +   EA +  RT   K    Q + +E R A  + +E+  K++  L ++ + + 
Sbjct: 480 QEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLH 539

Query: 157 VKRVVDKKRLSKLEPEPNTKTRESTSSEK-----VSQSPSKDSEENPATEERPEKILAET 211
           +    D + L + +    T TR+   S +     + Q+ +K + E        ++ L + 
Sbjct: 540 I----DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKV 595

Query: 212 QPELGTWGDGKGEDELSPEEIQ------------MFEQENQRLIGEMNSLFDEVRQIEGR 259
           + EL  W     E E     +Q               +E  RL GE+  L  E   +E  
Sbjct: 596 RAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETE 655

Query: 260 VVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENI 295
              + R   + + ++ +QE E+ +  +  +  T ++
Sbjct: 656 CHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDL 691


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 51/242 (21%), Positives = 108/242 (44%), Gaps = 12/242 (4%)

Query: 70  HRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRT--CSEAIQQLRTEAHKEIHSQQV 127
           H ++ I        E  ++ + E+ Q +Q+A+++ +     E  +++R E  K++  Q+ 
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIR-EQEKKMWRQEE 458

Query: 128 KEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTREST---SSE 184
           K H    +   E+  +   +++ ++  I  +  + +++    E E   + +E       E
Sbjct: 459 KIHEQEKIRE-EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517

Query: 185 KVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ--RL 242
           K+ +   K  E+      + EKI    Q E+    +   E E   EE +  EQE++  R 
Sbjct: 518 KIREQEEKIREQEEKMWRQEEKI--REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575

Query: 243 IGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDI 302
             ++    ++V + E ++ E    ++   EK+ +QE +I    + +    E I+E  E I
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635

Query: 303 RE 304
           RE
Sbjct: 636 RE 637



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 44/214 (20%), Positives = 91/214 (42%), Gaps = 21/214 (9%)

Query: 112 QQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK-KRLSKLE 170
           + LR E   ++H+ ++   +   L     Y +   K    +    + R+ D  K   +LE
Sbjct: 119 EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELE 178

Query: 171 PEPNTKTRESTSSEKVSQSPSKDSE-------ENPATEERPEKILAETQPELGTWGDGKG 223
              +    +   +++  +  +K+ +        N  T+E  ++  A+ Q +L      K 
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238

Query: 224 EDELSPEEIQMFEQE------NQRLIGEMNSLFDEVRQIEGRV---VEIS----RLQEIF 270
           E +L+ +E++   +        Q+L  E + L  E++ +  ++   VE +    RL +  
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298

Query: 271 TEKVLQQEAEIDSIHQLVVGATENIKEGNEDIRE 304
            EK+ +QE +I    + +    E I+E  E IRE
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 36/182 (19%), Positives = 80/182 (43%), Gaps = 16/182 (8%)

Query: 139 EDYLKRVCKLYSEQRAIRVK--RVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEE 196
           E+ ++ + +   EQ  IR +  +  +++++ + E     + +     EK+ +   K  E+
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449

Query: 197 NPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQI 256
                 + EKI  + +           E+E   E+ +M+ QE +  I E   ++ +  ++
Sbjct: 450 EKKMWRQEEKIHEQEKIR---------EEEKRQEQEEMWRQEEK--IHEQEEIWRQKEKM 498

Query: 257 EGRVVEISRLQEIF---TEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKNNAGFR 313
             +  +I + +E      EK+ +QE +I    + +    E I+E  E  RE  K +   +
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558

Query: 314 VW 315
           +W
Sbjct: 559 IW 560



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 37/190 (19%), Positives = 81/190 (42%), Gaps = 26/190 (13%)

Query: 117 EAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVV--DKKRLSKLEPEPN 174
           E  ++I  Q+ K  R       E+ ++   +++ E+  +  +  +  ++KR  + +    
Sbjct: 521 EQEEKIREQEEKMWRQ------EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574

Query: 175 TKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQM 234
            + +     EKV +   K  E+    +E+ EK+          W   K E+++  +E ++
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM----------W---KQEEKIREQEEKI 621

Query: 235 FEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATEN 294
            EQE +     +    +++R+ E    E         EK+ +QE ++    + +    E 
Sbjct: 622 QEQEEK-----IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676

Query: 295 IKEGNEDIRE 304
           I+E  + IRE
Sbjct: 677 IREQEKKIRE 686


>gi|170932494 syntaxin 7 [Homo sapiens]
          Length = 261

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 58/277 (20%), Positives = 113/277 (40%), Gaps = 66/277 (23%)

Query: 42  SPRPKGDFSSRAREVISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTE--RDQIDQD 99
           +P   GD +  A+ + S+I K+    +E ++        T+++ G   D+   R Q+ Q 
Sbjct: 4   TPGVGGDPAQLAQRISSNIQKITQCSVEIQR--------TLNQLGTPQDSPELRQQLQQK 55

Query: 100 AQIFMRTCSEAIQQLRT----------EAHKEIHSQQ-VKEHRTAVLDFIEDYLKRVCKL 148
            Q   +   E  + ++           +  ++I   + V E  T++ +F     ++V + 
Sbjct: 56  QQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNF-----QKVQRQ 110

Query: 149 YSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKIL 208
            +E+    V RV    R+S   PE ++K R   S E                        
Sbjct: 111 AAEREKEFVARVRASSRVSGSFPEDSSKERNLVSWE------------------------ 146

Query: 209 AETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQE 268
           ++TQP++    +   ED+L             RLI E  S    +RQ+E  +++I+ + +
Sbjct: 147 SQTQPQVQVQDEEITEDDL-------------RLIHERES---SIRQLEADIMDINEIFK 190

Query: 269 IFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREA 305
                + +Q   IDSI   V  A  ++++ N+ +  A
Sbjct: 191 DLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRA 227


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 58/271 (21%), Positives = 116/271 (42%), Gaps = 19/271 (7%)

Query: 37   ELFRRSPRPKGDFSSRAREVISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQI 96
            EL +   R K + SSR R++      L++   E  +   N     ++   ++ DT++ ++
Sbjct: 1322 ELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKK-KV 1380

Query: 97   DQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIR 156
            D D    + +  EA ++L  +A  E  SQ+++E +    D +E    R+     +Q    
Sbjct: 1381 DDDLGT-IESLEEAKKKLLKDA--EALSQRLEE-KALAYDKLEKTKNRL-----QQELDD 1431

Query: 157  VKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELG 216
            +   +D +R      E   K  +   +E+ S S     E + A  E  EK       E  
Sbjct: 1432 LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK-------ETK 1484

Query: 217  TWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQ 276
                 +  +E + E  + FE++N++L  +M  L      +   V E+ + +    ++V +
Sbjct: 1485 ALSLARALEE-ALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE 1543

Query: 277  QEAEIDSIHQLVVGATENIKEGNEDIREAIK 307
               +++ +    + ATE+ K   E   +A+K
Sbjct: 1544 MRTQLEELED-ELQATEDAKLRLEVNMQAMK 1573


>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
          Length = 955

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 50/210 (23%), Positives = 91/210 (43%), Gaps = 16/210 (7%)

Query: 89  TDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKL 148
           T     Q+ Q+A+ F    +E IQQ      ++ H QQ      A    +    +++ K 
Sbjct: 81  TQESEVQLLQNAKRF----TEQIQQ------QQFHLQQADNFPEAFSTEVSKMREQLLKY 130

Query: 149 YSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKIL 208
            +E  A++ +   ++ RL+ L+ E     +E     K  +   K      +TEE  ++I+
Sbjct: 131 QNEYNAVKEREFHNQYRLNSLKEEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIM 190

Query: 209 AETQPELGTWGDGKGEDELSPEEIQMFEQ-ENQRLIGEMNSLFDEVRQIEGRVVEISRLQ 267
              Q +L        ED  S ++  + EQ E + L+G    L DEV   +   V+I +  
Sbjct: 191 ---QKKLEI--KNLREDLASKQKQLLKEQKELEELLGHQVVLKDEVAHHQTIPVQIGKEI 245

Query: 268 EIFTEKVLQQEAEIDSIHQLVVGATENIKE 297
           E  T K ++ E +   + Q V    +++K+
Sbjct: 246 EKITRKKVEMEKKKIVLEQEVKTLNDSLKK 275


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 52/286 (18%), Positives = 122/286 (42%), Gaps = 23/286 (8%)

Query: 36  DELFRRSPRPKGDFSSRAREVISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQ 95
           +EL+ R  + + +   R  E I      R+  ++ +++ I      M     M   + ++
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQE----REEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331

Query: 96  IDQDAQIFMRTCSEAIQQLRTEAHKE--IHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQR 153
           + +  ++      E I++L  + H++  I  Q+ K      +   E   ++  K++ ++ 
Sbjct: 332 MRRQEEMMWEK-EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 390

Query: 154 AIRVK--RVVDKKRLSKLEPEPNTKTREST---------SSEKVSQSPSKDSEENPATEE 202
            IR +  ++ +++ + + + E   +  E             EK+ +   K  E+     E
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE 450

Query: 203 RPEKILAETQPELGTWGDGKGEDE--LSPEEIQMFEQENQ--RLIGEMNSLFDEVRQIEG 258
           + EKI  E +  +    +  GE E  +  +E +M EQE +  R   ++     ++R+ E 
Sbjct: 451 QEEKI-REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509

Query: 259 RVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIRE 304
           ++ E   + +   EK+ +QE ++    + +    E ++   E +RE
Sbjct: 510 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555



 Score = 35.8 bits (81), Expect = 0.055
 Identities = 34/173 (19%), Positives = 78/173 (45%), Gaps = 17/173 (9%)

Query: 139 EDYLKRVCKLYSEQRAIRVK--RVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEE 196
           E+ ++ + +   EQ  IR +  +  +++++ + E     + +     EK+ +   K  E+
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402

Query: 197 NPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ--RLIGEMNSLFDEVR 254
               +E+ EK+             G+ E+++  +E +M EQE +  R   ++     ++R
Sbjct: 403 EEMMQEQEEKM-------------GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449

Query: 255 QIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIK 307
           + E ++ E   + +   EK+ +QE ++      +    E ++   E IRE  K
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 38/207 (18%), Positives = 84/207 (40%), Gaps = 14/207 (6%)

Query: 112 QQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK-KRLSKLE 170
           + LR E   ++ + ++   +   L     Y +   K    +    + R+ D  K   +LE
Sbjct: 107 EALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELE 166

Query: 171 PEPNTKTRESTSSEKVSQSPSKDSE-------ENPATEERPEKILAETQPELGTWGDGKG 223
              +    +   +++  +  +K+ +        N  T+E  ++  A+ Q +L      K 
Sbjct: 167 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 226

Query: 224 EDELSPEEIQMFEQE------NQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQ 277
           E +L+ +E++   +        Q+L  E + L  E++ +  ++       E++     QQ
Sbjct: 227 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 286

Query: 278 EAEIDSIHQLVVGATENIKEGNEDIRE 304
           E ++    + +    E I+E  E IRE
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIRE 313


>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
          Length = 287

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 38/169 (22%), Positives = 76/169 (44%), Gaps = 21/169 (12%)

Query: 176 KTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSP------ 229
           +T+ S  S K  ++ ++ +E      ER +      Q +L   G    +DEL        
Sbjct: 116 RTQHSVLSRKFVEAMAEYNEAQTLFRERSK---GRIQRQLEITGRTTTDDELEEMLESGK 172

Query: 230 -----EEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAE---I 281
                 +I    Q  ++ + E+ S   ++ ++E     I  L E+F +  +  E +   I
Sbjct: 173 PSIFTSDIISDSQITRQALNEIESRHKDIMKLE---TSIRELHEMFMDMAMFVETQGEMI 229

Query: 282 DSIHQLVVGATENIKEGNEDIREAIKNNAGFRVWILFFLVMCSFSLLFL 330
           ++I + V+ AT+ ++   E+ ++AIK  +  R   L F+++C   LL +
Sbjct: 230 NNIERNVMNATDYVEHAKEETKKAIKYQSKAR-RKLMFIIICVIVLLVI 277


>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
            sapiens]
          Length = 1782

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 52/212 (24%), Positives = 90/212 (42%), Gaps = 25/212 (11%)

Query: 82   MSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDY 141
            +SEY  +   ER++++  AQ   ++  +  Q+  TE  KE+   QV     AV D     
Sbjct: 849  LSEYDAV---EREKME--AQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADG---- 899

Query: 142  LKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVS-QSPSKDSEENPAT 200
              R   +  E+    +   V +  L ++E E    T E    E ++ + P   +E  P  
Sbjct: 900  -TRAATIIEERSPSWISASVTEP-LEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPEN 957

Query: 201  EE-RPEKILAETQ--PELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDE----- 252
             E R + +++E +  PE  T  +  G             +E   ++  ++ L D      
Sbjct: 958  REARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTE 1017

Query: 253  ----VRQIEGRVVEISRLQEIFTEKVLQQEAE 280
                V+++EG V +I   QE  T++VLQ  AE
Sbjct: 1018 EATPVQEVEGGVPDIEE-QERRTQEVLQAVAE 1048



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 29/132 (21%), Positives = 53/132 (40%), Gaps = 17/132 (12%)

Query: 182 SSEKVSQSPSK-DSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ 240
           S +K  Q P K D+EE+   E   EK+ A  Q       +   E  LS E  ++     +
Sbjct: 324 SEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEE 383

Query: 241 RLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKV-LQQEAEIDSIHQLVVGATENIKEGN 299
           ++ G      ++   +           E+F EK+ + QE  +  +H         ++E  
Sbjct: 384 QVSGSQGPSEEKPAPL---------ATEVFDEKIEVHQEEVVAEVH------VSTVEERT 428

Query: 300 EDIREAIKNNAG 311
           E+ +  ++  AG
Sbjct: 429 EEQKTEVEETAG 440


>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
           sapiens]
          Length = 1684

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 52/212 (24%), Positives = 90/212 (42%), Gaps = 25/212 (11%)

Query: 82  MSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDY 141
           +SEY  +   ER++++  AQ   ++  +  Q+  TE  KE+   QV     AV D     
Sbjct: 751 LSEYDAV---EREKME--AQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADG---- 801

Query: 142 LKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVS-QSPSKDSEENPAT 200
             R   +  E+    +   V +  L ++E E    T E    E ++ + P   +E  P  
Sbjct: 802 -TRAATIIEERSPSWISASVTEP-LEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPEN 859

Query: 201 EE-RPEKILAETQ--PELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDE----- 252
            E R + +++E +  PE  T  +  G             +E   ++  ++ L D      
Sbjct: 860 REARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTE 919

Query: 253 ----VRQIEGRVVEISRLQEIFTEKVLQQEAE 280
               V+++EG V +I   QE  T++VLQ  AE
Sbjct: 920 EATPVQEVEGGVPDIEE-QERRTQEVLQAVAE 950



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 29/132 (21%), Positives = 53/132 (40%), Gaps = 17/132 (12%)

Query: 182 SSEKVSQSPSK-DSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQ 240
           S +K  Q P K D+EE+   E   EK+ A  Q       +   E  LS E  ++     +
Sbjct: 226 SEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEE 285

Query: 241 RLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKV-LQQEAEIDSIHQLVVGATENIKEGN 299
           ++ G      ++   +           E+F EK+ + QE  +  +H         ++E  
Sbjct: 286 QVSGSQGPSEEKPAPL---------ATEVFDEKIEVHQEEVVAEVH------VSTVEERT 330

Query: 300 EDIREAIKNNAG 311
           E+ +  ++  AG
Sbjct: 331 EEQKTEVEETAG 342


>gi|52856430 protein expressed in prostate, ovary, testis, and
           placenta 15 [Homo sapiens]
          Length = 581

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 62/239 (25%), Positives = 96/239 (40%), Gaps = 33/239 (13%)

Query: 94  DQIDQDAQIFMRTCSEA-IQQLRTEAHKEIHSQQ----------VKEHRTAVLDFIEDYL 142
           D+  + A I    C  A I  L  E + ++ SQ           V  H   + + + DY 
Sbjct: 302 DRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYK 361

Query: 143 -KRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSP--SKDSEENPA 199
            K++ K+ SE             +L+  E     K  E++  EK+SQ P  +KD +    
Sbjct: 362 EKQMLKISSEN-----SNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVE 416

Query: 200 TEERPEKILAETQPELGTWG--DGKGEDELSPEEIQMFEQENQRLIGEMNSLF--DEVRQ 255
            E +         PE  T G   G G+D L P+  +  + ENQ+     N  +  DE   
Sbjct: 417 EEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQR-KSRKPENQQFPDTENEEYHSDEQND 475

Query: 256 IEGRVVE-----ISRLQEIFTEKVLQ---QEAEIDSIHQLVVGATENIKEGNEDIREAI 306
            + ++ E     IS+  EI T K  Q    E E++S   L     E++   N  +RE I
Sbjct: 476 TQKQLSEEQNTGISQ-DEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEI 533


>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
           sapiens]
          Length = 544

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 62/239 (25%), Positives = 96/239 (40%), Gaps = 33/239 (13%)

Query: 94  DQIDQDAQIFMRTCSEA-IQQLRTEAHKEIHSQQ----------VKEHRTAVLDFIEDYL 142
           D+  + A I    C  A I  L  E + ++ SQ           V  H   + + + DY 
Sbjct: 265 DRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYK 324

Query: 143 -KRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSP--SKDSEENPA 199
            K++ K+ SE             +L+  E     K  E++  EK+SQ P  +KD +    
Sbjct: 325 EKQMLKISSEN-----SNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVE 379

Query: 200 TEERPEKILAETQPELGTWG--DGKGEDELSPEEIQMFEQENQRLIGEMNSLF--DEVRQ 255
            E +         PE  T G   G G+D L P+  +  + ENQ+     N  +  DE   
Sbjct: 380 EEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQR-KSRKPENQQFPDTENEEYHSDEQND 438

Query: 256 IEGRVVE-----ISRLQEIFTEKVLQ---QEAEIDSIHQLVVGATENIKEGNEDIREAI 306
            + ++ E     IS+  EI T K  Q    E E++S   L     E++   N  +RE I
Sbjct: 439 TQKQLSEEQNTGISQ-DEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEI 496


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 54/238 (22%), Positives = 98/238 (41%), Gaps = 30/238 (12%)

Query: 92  ERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSE 151
           E  Q ++ A+    T  E I  L+    KE+H  +++   TA+    + Y K V  L +E
Sbjct: 449 ENKQFEKIAEELKGTEQELIGLLQAR-EKEVHDLEIQ--LTAITTSEQYYSKEVKDLKTE 505

Query: 152 QRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEK---IL 208
               ++K        +KL  E    T+E++      ++  +D   N   EER  K    L
Sbjct: 506 LENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENL 565

Query: 209 AETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVR-QIEGRVVEISRLQ 267
            ET+ +L      + E E   EE++    E +  + +     + +R Q+E +   I  LQ
Sbjct: 566 QETETQL------RNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQ 619

Query: 268 E-----------------IFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKN 308
           +                 ++  KV + E E++S  Q     T+  ++  ED + + +N
Sbjct: 620 QENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEEN 677


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 36.6 bits (83), Expect = 0.032
 Identities = 49/229 (21%), Positives = 99/229 (43%), Gaps = 39/229 (17%)

Query: 115 RTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRA----------IRVKRVVDKK 164
           R E  KE  +Q + E +T + D +E    R  KL+  ++           + ++R +D+K
Sbjct: 345 RVEELKE-DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRK 403

Query: 165 RLSKLEPEPNT-----------------KTRESTSSEKVSQSPSKD--SEENPATEERPE 205
           ++ +L  E  T                 +  + + + ++S++P K    E N  T  R  
Sbjct: 404 KIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL 463

Query: 206 KI------LAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGR 259
           K+      L +T  EL T  D     E +  +I   E+ENQRL  ++  L +E+ Q +  
Sbjct: 464 KLEMENQSLTKTVEELRTTVDSV---EGNASKILKMEKENQRLSKKVEILENEIVQEKQS 520

Query: 260 VVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKN 308
           +     L +   ++  Q E  I+++ +      + +++ NE + + + +
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 36.6 bits (83), Expect = 0.032
 Identities = 49/229 (21%), Positives = 99/229 (43%), Gaps = 39/229 (17%)

Query: 115 RTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRA----------IRVKRVVDKK 164
           R E  KE  +Q + E +T + D +E    R  KL+  ++           + ++R +D+K
Sbjct: 345 RVEELKE-DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRK 403

Query: 165 RLSKLEPEPNT-----------------KTRESTSSEKVSQSPSKD--SEENPATEERPE 205
           ++ +L  E  T                 +  + + + ++S++P K    E N  T  R  
Sbjct: 404 KIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL 463

Query: 206 KI------LAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGR 259
           K+      L +T  EL T  D     E +  +I   E+ENQRL  ++  L +E+ Q +  
Sbjct: 464 KLEMENQSLTKTVEELRTTVDSV---EGNASKILKMEKENQRLSKKVEILENEIVQEKQS 520

Query: 260 VVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKN 308
           +     L +   ++  Q E  I+++ +      + +++ NE + + + +
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,961,800
Number of Sequences: 37866
Number of extensions: 548995
Number of successful extensions: 4348
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 363
Number of HSP's that attempted gapping in prelim test: 3821
Number of HSP's gapped (non-prelim): 846
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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