Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 83716021
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83716021 GRB2-associated binding protein family, member 4
[Homo sapiens]
(574 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83716021 GRB2-associated binding protein family, member 4 [Ho... 1190 0.0
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa... 362 e-100
gi|6912460 GRB2-associated binding protein 2 isoform b [Homo sap... 306 3e-83
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa... 169 8e-42
gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa... 169 8e-42
gi|126091130 Gab3 protein isoform 1 [Homo sapiens] 134 2e-31
gi|18079323 Gab3 protein isoform 2 [Homo sapiens] 134 2e-31
gi|154354979 myosin X [Homo sapiens] 57 6e-08
gi|154146216 pleckstrin homology domain containing, family A (ph... 57 6e-08
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 50 4e-06
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 50 6e-06
gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 50 6e-06
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 50 6e-06
gi|50234893 pleckstrin homology domain containing, family A (pho... 50 7e-06
gi|31377720 pleckstrin homology domain containing, family A (pho... 50 7e-06
gi|156616273 pleckstrin [Homo sapiens] 49 1e-05
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit... 48 3e-05
gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Ho... 46 1e-04
gi|5031805 insulin receptor substrate 1 [Homo sapiens] 45 1e-04
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 45 2e-04
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 45 2e-04
gi|46391075 hypothetical protein LOC79949 [Homo sapiens] 44 3e-04
gi|55741447 pleckstrin homology domain containing, family H (wit... 44 4e-04
gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1 [... 43 7e-04
gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1 [... 43 7e-04
gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [H... 43 7e-04
gi|197313732 pleckstrin homology-like domain, family B, member 2... 43 7e-04
gi|197313730 pleckstrin homology-like domain, family B, member 2... 43 7e-04
gi|197313728 pleckstrin homology-like domain, family B, member 2... 43 7e-04
gi|21955172 pleckstrin homology-like domain, family B, member 2 ... 43 7e-04
>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
sapiens]
Length = 574
Score = 1190 bits (3079), Expect = 0.0
Identities = 574/574 (100%), Positives = 574/574 (100%)
Query: 1 MSLPSPSPSRELCPPDPAFAPLSSWPGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAW 60
MSLPSPSPSRELCPPDPAFAPLSSWPGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAW
Sbjct: 1 MSLPSPSPSRELCPPDPAFAPLSSWPGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAW 60
Query: 61 RKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYM 120
RKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYM
Sbjct: 61 RKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYM 120
Query: 121 FDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEESTGFLGNISSASHGLCSSPAEPS 180
FDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEESTGFLGNISSASHGLCSSPAEPS
Sbjct: 121 FDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEESTGFLGNISSASHGLCSSPAEPS 180
Query: 181 CSHQHLPQEQEPTSEPPVSHCVPPTWPIPAPPGCLRSHQHASQRAEHARSASFSQGSEAP 240
CSHQHLPQEQEPTSEPPVSHCVPPTWPIPAPPGCLRSHQHASQRAEHARSASFSQGSEAP
Sbjct: 181 CSHQHLPQEQEPTSEPPVSHCVPPTWPIPAPPGCLRSHQHASQRAEHARSASFSQGSEAP 240
Query: 241 FIMRRNTAMQNLAQHSGYSVDGVSGHIHGFHSLSKPSQHNAEFRGSTHRIPWSLASHGHT 300
FIMRRNTAMQNLAQHSGYSVDGVSGHIHGFHSLSKPSQHNAEFRGSTHRIPWSLASHGHT
Sbjct: 241 FIMRRNTAMQNLAQHSGYSVDGVSGHIHGFHSLSKPSQHNAEFRGSTHRIPWSLASHGHT 300
Query: 301 RGSLTGSEADNEASSGKYTQHGGGNASRPAESMHEGVCSFLPGRTLVGLSDSIASEGSCV 360
RGSLTGSEADNEASSGKYTQHGGGNASRPAESMHEGVCSFLPGRTLVGLSDSIASEGSCV
Sbjct: 301 RGSLTGSEADNEASSGKYTQHGGGNASRPAESMHEGVCSFLPGRTLVGLSDSIASEGSCV 360
Query: 361 PMNPGSPTLPAVKQAGDDSQGVCIPVGSCLVRFDLLGSPLTELSMHQDLSQGHEVQLPPV 420
PMNPGSPTLPAVKQAGDDSQGVCIPVGSCLVRFDLLGSPLTELSMHQDLSQGHEVQLPPV
Sbjct: 361 PMNPGSPTLPAVKQAGDDSQGVCIPVGSCLVRFDLLGSPLTELSMHQDLSQGHEVQLPPV 420
Query: 421 NRSLKPNQKANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITNT 480
NRSLKPNQKANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITNT
Sbjct: 421 NRSLKPNQKANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITNT 480
Query: 481 DSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVD 540
DSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVD
Sbjct: 481 DSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVD 540
Query: 541 YVQVDLEKTQALQKTMHEQMCLRQSSEPPRGAKL 574
YVQVDLEKTQALQKTMHEQMCLRQSSEPPRGAKL
Sbjct: 541 YVQVDLEKTQALQKTMHEQMCLRQSSEPPRGAKL 574
>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
sapiens]
Length = 676
Score = 362 bits (930), Expect = e-100
Identities = 187/288 (64%), Positives = 220/288 (76%), Gaps = 15/288 (5%)
Query: 38 GHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLN 97
G V+ +GWLRKSPPEKKLR +AW+KRWFILR G+ S DPDVLEYYKND SKKPLR INLN
Sbjct: 5 GDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIINLN 64
Query: 98 LCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQ-E 156
CEQ+D +T FNKKE+Q ++FDIKTSERTFYLVAET EDMN+WVQSICQICGF Q E
Sbjct: 65 FCEQVDAGLT--FNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQAE 122
Query: 157 ESTGFLGNISSASHGLCSSPAEPSCSHQHLPQEQEP------------TSEPPVSHCVPP 204
EST L N+SSA HG SSPAE S S QHL +E++ T EPPVS+ + P
Sbjct: 123 ESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQP 182
Query: 205 TWPIPAPPGCLRSHQHASQRAEHARSASFSQGSEAPFIMRRNTAMQNLAQHSGYSVDGVS 264
T AP L HQ S+RAE+ARSASFSQG+ A F+MR +TA+Q LAQ +G+ V+G+S
Sbjct: 183 TLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGIS 242
Query: 265 GHIHGFHSLSKPSQHNAEFRGSTHRIPWSLASHGHTRGSLTGSEADNE 312
G +HGF+SL KPS+HN EFR ST+ +P SLASHGHT+GSLTGSE DNE
Sbjct: 243 GQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNE 290
Score = 295 bits (755), Expect = 8e-80
Identities = 161/267 (60%), Positives = 195/267 (73%), Gaps = 9/267 (3%)
Query: 317 KYTQHGGGNASRPAESMHEGVCSFLPGRTLVGLSDSIASEGSCVPMNPGSPTLPAVKQAG 376
+Y Q GG +A R AESM +GV SFLPG+ +VG SDS SE + VPMNPGS TL A+++AG
Sbjct: 410 EYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAG 469
Query: 377 DDSQGVCIPVGSCLVRFDLLGSPLTELSMHQDLSQGHEVQLPPVNRSLKPNQKANPTPPN 436
D+SQ V IP+ FD LG P T L +H+ S+G E+Q PPVNR+LKP++KA PTP +
Sbjct: 470 DNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLD 529
Query: 437 LRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQH--PISTQSITNTDSEDSGERYL-FPN 493
LRNN VI+EL FK P+T+ WS +HTF+SSSSQ+ PISTQSIT+TDS DS E Y+ N
Sbjct: 530 LRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQN 589
Query: 494 PASAFPVSGGTSSSAPPRSTGNIHYAALDFQPS------KPSIGSVTSGKKVDYVQVDLE 547
P SA PV GT+S AP +STG++ Y ALDFQPS KPS SVTS +KVDYVQVD E
Sbjct: 590 PVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKE 649
Query: 548 KTQALQKTMHEQMCLRQSSEPPRGAKL 574
KTQALQ TM E +RQSSEP +GAKL
Sbjct: 650 KTQALQNTMQEWTDVRQSSEPSKGAKL 676
>gi|6912460 GRB2-associated binding protein 2 isoform b [Homo
sapiens]
Length = 638
Score = 306 bits (785), Expect = 3e-83
Identities = 162/253 (64%), Positives = 190/253 (75%), Gaps = 15/253 (5%)
Query: 73 SSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYL 132
S DPDVLEYYKND SKKPLR INLN CEQ+D +T FNKKE+Q ++FDIKTSERTFYL
Sbjct: 2 SGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLT--FNKKELQDSFVFDIKTSERTFYL 59
Query: 133 VAETREDMNEWVQSICQICGFRQ-EESTGFLGNISSASHGLCSSPAEPSCSHQHLPQEQE 191
VAET EDMN+WVQSICQICGF Q EEST L N+SSA HG SSPAE S S QHL +E++
Sbjct: 60 VAETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERK 119
Query: 192 P------------TSEPPVSHCVPPTWPIPAPPGCLRSHQHASQRAEHARSASFSQGSEA 239
T EPPVS+ + PT AP L HQ S+RAE+ARSASFSQG+ A
Sbjct: 120 SSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRA 179
Query: 240 PFIMRRNTAMQNLAQHSGYSVDGVSGHIHGFHSLSKPSQHNAEFRGSTHRIPWSLASHGH 299
F+MR +TA+Q LAQ +G+ V+G+SG +HGF+SL KPS+HN EFR ST+ +P SLASHGH
Sbjct: 180 SFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGH 239
Query: 300 TRGSLTGSEADNE 312
T+GSLTGSE DNE
Sbjct: 240 TKGSLTGSETDNE 252
Score = 295 bits (755), Expect = 8e-80
Identities = 161/267 (60%), Positives = 195/267 (73%), Gaps = 9/267 (3%)
Query: 317 KYTQHGGGNASRPAESMHEGVCSFLPGRTLVGLSDSIASEGSCVPMNPGSPTLPAVKQAG 376
+Y Q GG +A R AESM +GV SFLPG+ +VG SDS SE + VPMNPGS TL A+++AG
Sbjct: 372 EYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAG 431
Query: 377 DDSQGVCIPVGSCLVRFDLLGSPLTELSMHQDLSQGHEVQLPPVNRSLKPNQKANPTPPN 436
D+SQ V IP+ FD LG P T L +H+ S+G E+Q PPVNR+LKP++KA PTP +
Sbjct: 432 DNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLD 491
Query: 437 LRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQH--PISTQSITNTDSEDSGERYL-FPN 493
LRNN VI+EL FK P+T+ WS +HTF+SSSSQ+ PISTQSIT+TDS DS E Y+ N
Sbjct: 492 LRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQN 551
Query: 494 PASAFPVSGGTSSSAPPRSTGNIHYAALDFQPS------KPSIGSVTSGKKVDYVQVDLE 547
P SA PV GT+S AP +STG++ Y ALDFQPS KPS SVTS +KVDYVQVD E
Sbjct: 552 PVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKE 611
Query: 548 KTQALQKTMHEQMCLRQSSEPPRGAKL 574
KTQALQ TM E +RQSSEP +GAKL
Sbjct: 612 KTQALQNTMQEWTDVRQSSEPSKGAKL 638
>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
sapiens]
Length = 694
Score = 169 bits (427), Expect = 8e-42
Identities = 75/120 (62%), Positives = 95/120 (79%), Gaps = 2/120 (1%)
Query: 38 GHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLN 97
G V+ SGWLRKSPPEKKL+ +AW++RWF+LR G+ + DPDVLEYYKND +KKP+R I+LN
Sbjct: 4 GEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLN 63
Query: 98 LCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEE 157
LC+Q VD L FNKKE + Y+FDI T +R FYLVA++ E+MN+WV+ IC ICGF E
Sbjct: 64 LCQQ--VDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTE 121
Score = 70.5 bits (171), Expect = 4e-12
Identities = 58/177 (32%), Positives = 83/177 (46%), Gaps = 23/177 (12%)
Query: 418 PPVNRSLKPNQKANPTPPNLRNNRVINELS--FKPPVTEPWSGTSHTFDSSSSQHPISTQ 475
PPV+R+LKP++K P P ++ EL + P+T ++ S F S P S
Sbjct: 517 PPVDRNLKPDRKVKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSP--RPDSVH 574
Query: 476 SITNT-DSEDSGERY--LFPNPASAFP-------VSGGTSSSAPPRSTGNIHYAALDFQP 525
S T++ DS DS E Y + PN +S P + GG+S P+ + Y LD
Sbjct: 575 STTSSSDSHDSEENYVPMNPNLSSEDPNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDS 634
Query: 526 SKPS---------IGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPPRGAK 573
K + GS + ++VDYV VD +KT AL+ T RQS+E AK
Sbjct: 635 GKSTPPRKQKSSGSGSSVADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPAK 691
>gi|46370071 GRB2-associated binding protein 1 isoform a [Homo
sapiens]
Length = 724
Score = 169 bits (427), Expect = 8e-42
Identities = 75/120 (62%), Positives = 95/120 (79%), Gaps = 2/120 (1%)
Query: 38 GHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLN 97
G V+ SGWLRKSPPEKKL+ +AW++RWF+LR G+ + DPDVLEYYKND +KKP+R I+LN
Sbjct: 4 GEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLN 63
Query: 98 LCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEE 157
LC+Q VD L FNKKE + Y+FDI T +R FYLVA++ E+MN+WV+ IC ICGF E
Sbjct: 64 LCQQ--VDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTE 121
Score = 56.2 bits (134), Expect = 8e-08
Identities = 60/209 (28%), Positives = 91/209 (43%), Gaps = 57/209 (27%)
Query: 418 PPVNRSLKPNQKANPTPPNLR---------NNRVINE-----------LSFKP------- 450
PPV+R+LKP++K +P LR +++ I + L KP
Sbjct: 517 PPVDRNLKPDRKGQ-SPKILRLKPHGLERTDSQTIGDFATRRKVKPAPLEIKPLPEWEEL 575
Query: 451 --PVTEPWSGTSHTFDSSSSQHPISTQ------SITNTDSEDSGERY--LFPNPASAFP- 499
PV P + +F SS+ P+S + + +++DS DS E Y + PN +S P
Sbjct: 576 QAPVRSP---ITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNPNLSSEDPN 632
Query: 500 ------VSGGTSSSAPPRSTGNIHYAALDFQPSKPS---------IGSVTSGKKVDYVQV 544
+ GG+S P+ + Y LD K + GS + ++VDYV V
Sbjct: 633 LFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERVDYVVV 692
Query: 545 DLEKTQALQKTMHEQMCLRQSSEPPRGAK 573
D +KT AL+ T RQS+E AK
Sbjct: 693 DQQKTLALKSTREAWTDGRQSTESETPAK 721
>gi|126091130 Gab3 protein isoform 1 [Homo sapiens]
Length = 587
Score = 134 bits (338), Expect = 2e-31
Identities = 71/160 (44%), Positives = 101/160 (63%), Gaps = 4/160 (2%)
Query: 37 SGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINL 96
+G + +GWL KSPPE+KL+ +AWRKRWF+LRRG+ S +PDVLEYY+N S KP+R I+L
Sbjct: 3 AGDAVCTGWLVKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSSKPIRVIDL 62
Query: 97 NLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQE 156
+ C + V +F +KE Q ++F +KT+ RTFYLVA+T ++M WV SI Q+C
Sbjct: 63 SEC-AVWKHVGPSFVRKEFQNNFVFIVKTTSRTFYLVAKTEQEMQVWVHSISQVCNLGHL 121
Query: 157 ESTGFLGNISSASHGLCSSPAEPSCSHQHLPQEQEPTSEP 196
E G ++ S S+ S +PS + L +S P
Sbjct: 122 ED-GAADSMESLSY--TPSSLQPSSASSLLTAHAASSSLP 158
Score = 76.3 bits (186), Expect = 7e-14
Identities = 75/221 (33%), Positives = 100/221 (45%), Gaps = 29/221 (13%)
Query: 352 SIASEGSCVPMNPGSPTLPAVKQAGDDSQGV-CIPVGSCLVRFDLLGSPLTELSMHQDLS 410
S + E S VPM+P QAG G C P + + SPL EL +
Sbjct: 387 SASIEDSYVPMSP---------QAGASGLGPHCSPDDYIPMNSGSISSPLPELPAN---- 433
Query: 411 QGHEVQLPPVNRSLKPNQKANPTPPNLRNNRVINE-LSFKPPVTEPWSGTSHTFDSSSSQ 469
++ PPVNR LKP +K+ P P +LRN +I E S T P S TS F S
Sbjct: 434 ----LEPPPVNRDLKPQRKSRPPPLDLRNLSIIREHASLTRTRTVPCSRTS--FLSPERN 487
Query: 470 HPISTQSITNTDSEDSGERYL-FPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKP 528
S + N S + E Y+ +A +S G + S + Y ALDF + P
Sbjct: 488 GINSARFFANPVSREDEESYIEMEEHRTASSLSSGALTWTKKFS---LDYLALDFNSASP 544
Query: 529 SIGS----VTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQS 565
+ ++ ++VDYVQVD +KTQALQ T E RQS
Sbjct: 545 APMQQKLLLSEEQRVDYVQVDEQKTQALQSTKQEWTDERQS 585
>gi|18079323 Gab3 protein isoform 2 [Homo sapiens]
Length = 586
Score = 134 bits (338), Expect = 2e-31
Identities = 71/160 (44%), Positives = 98/160 (61%), Gaps = 5/160 (3%)
Query: 37 SGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINL 96
+G + +GWL KSPPE+KL+ +AWRKRWF+LRRG+ S +PDVLEYY+N S KP+R I+L
Sbjct: 3 AGDAVCTGWLVKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSSKPIRVIDL 62
Query: 97 NLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQE 156
+ C + V +F +KE Q ++F +KT+ RTFYLVA+T ++M WV SI Q+C
Sbjct: 63 SEC-AVWKHVGPSFVRKEFQNNFVFIVKTTSRTFYLVAKTEQEMQVWVHSISQVCNLGHL 121
Query: 157 ESTGFLGNISSASHGLCSSPAEPSCSHQHLPQEQEPTSEP 196
E G S S S +PS + L +S P
Sbjct: 122 ED----GADSMESLSYTPSSLQPSSASSLLTAHAASSSLP 157
Score = 76.3 bits (186), Expect = 7e-14
Identities = 75/221 (33%), Positives = 100/221 (45%), Gaps = 29/221 (13%)
Query: 352 SIASEGSCVPMNPGSPTLPAVKQAGDDSQGV-CIPVGSCLVRFDLLGSPLTELSMHQDLS 410
S + E S VPM+P QAG G C P + + SPL EL +
Sbjct: 386 SASIEDSYVPMSP---------QAGASGLGPHCSPDDYIPMNSGSISSPLPELPAN---- 432
Query: 411 QGHEVQLPPVNRSLKPNQKANPTPPNLRNNRVINE-LSFKPPVTEPWSGTSHTFDSSSSQ 469
++ PPVNR LKP +K+ P P +LRN +I E S T P S TS F S
Sbjct: 433 ----LEPPPVNRDLKPQRKSRPPPLDLRNLSIIREHASLTRTRTVPCSRTS--FLSPERN 486
Query: 470 HPISTQSITNTDSEDSGERYL-FPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKP 528
S + N S + E Y+ +A +S G + S + Y ALDF + P
Sbjct: 487 GINSARFFANPVSREDEESYIEMEEHRTASSLSSGALTWTKKFS---LDYLALDFNSASP 543
Query: 529 SIGS----VTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQS 565
+ ++ ++VDYVQVD +KTQALQ T E RQS
Sbjct: 544 APMQQKLLLSEEQRVDYVQVDEQKTQALQSTKQEWTDERQS 584
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 56.6 bits (135), Expect = 6e-08
Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 17/118 (14%)
Query: 41 LYSGWL-RKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLC 99
L GWL +K L W+KRWF+LR+ + L Y++ND +K T+ +
Sbjct: 1214 LKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSK-------LMYFENDSEEKLKGTVEVRTA 1266
Query: 100 EQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEE 157
+++ +D T N DI ++RTF+L+AE+ ED ++W + Q+ +E
Sbjct: 1267 KEI-IDNTTKENG--------IDIIMADRTFHLIAESPEDASQWFSVLSQVHASTDQE 1315
>gi|154146216 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 2 [Homo
sapiens]
Length = 425
Score = 56.6 bits (135), Expect = 6e-08
Identities = 51/190 (26%), Positives = 83/190 (43%), Gaps = 31/190 (16%)
Query: 36 RSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTIN 95
+SG+ + G +RKS W++R+F L D + Y+K + ++PLRTI
Sbjct: 201 KSGYCVKQGNVRKS----------WKRRFFAL-------DDFTICYFKCEQDREPLRTIF 243
Query: 96 LNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSI-----CQI 150
L + L L + + + +F+I TS RTFY+ A++ EDM+ W++ I
Sbjct: 244 LK--DVLKTHECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAVQALK 301
Query: 151 CGFRQEESTGFLGNISSASHGLCSSPAEPSC-SHQHLPQEQEPTSEPPVSHCVPPTWPIP 209
C R+ + + S L S P C L +++ P V+ P P+P
Sbjct: 302 CHPRETSFSRSISLTRPGSSSLSSGPNSILCRGRPPLEEKKALCKAPSVASSWQPWTPVP 361
Query: 210 ------APPG 213
PPG
Sbjct: 362 QAGEKLLPPG 371
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 50.4 bits (119), Expect = 4e-06
Identities = 41/134 (30%), Positives = 70/134 (52%), Gaps = 20/134 (14%)
Query: 23 SSWPGSGPAGGSTRSGHVLYSGWLRK----SPPEKKLRLFAWRKRWFILRRGQTSSDPDV 78
SS G G AGG+ V SGWL K S + + +++KR+F L Q + +
Sbjct: 169 SSSKGGGGAGGTG----VFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLT--QLPDNSYI 222
Query: 79 LEYYKNDG-SKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFY-LVAET 136
+ +YK++ SK+P I L+ C + + L + Y F++K ++ T++ L AET
Sbjct: 223 MNFYKDEKISKEPKGCIFLDSCTGVVQNNRL--------RKYAFELKMNDLTYFVLAAET 274
Query: 137 REDMNEWVQSICQI 150
DM+EW+ ++ +I
Sbjct: 275 ESDMDEWIHTLNRI 288
>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform d [Homo sapiens]
Length = 1133
Score = 50.1 bits (118), Expect = 6e-06
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 21/124 (16%)
Query: 26 PGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKND 85
P GP GGST V+ +GWL K+PP+ + ++KRW L D D L Y+ ++
Sbjct: 69 PMDGPPGGSTPVTPVIKAGWLDKNPPQGS---YIYQKRWVRL-------DTDHLRYFDSN 118
Query: 86 GSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQ 145
R I++ + + K F++ T+ RTF AE+ + EW+Q
Sbjct: 119 KDAYSKRFISVACISHV---AAIGDQK--------FEVITNNRTFAFRAESDVERKEWMQ 167
Query: 146 SICQ 149
++ Q
Sbjct: 168 ALQQ 171
>gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform a [Homo sapiens]
Length = 1205
Score = 50.1 bits (118), Expect = 6e-06
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 21/124 (16%)
Query: 26 PGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKND 85
P GP GGST V+ +GWL K+PP+ + ++KRW L D D L Y+ ++
Sbjct: 69 PMDGPPGGSTPVTPVIKAGWLDKNPPQGS---YIYQKRWVRL-------DTDHLRYFDSN 118
Query: 86 GSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQ 145
R I++ + + K F++ T+ RTF AE+ + EW+Q
Sbjct: 119 KDAYSKRFISVACISHV---AAIGDQK--------FEVITNNRTFAFRAESDVERKEWMQ 167
Query: 146 SICQ 149
++ Q
Sbjct: 168 ALQQ 171
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 50.1 bits (118), Expect = 6e-06
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 21/124 (16%)
Query: 26 PGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKND 85
P GP GGST V+ +GWL K+PP+ + ++KRW L D D L Y+ ++
Sbjct: 314 PMDGPPGGSTPVTPVIKAGWLDKNPPQGS---YIYQKRWVRL-------DTDHLRYFDSN 363
Query: 86 GSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQ 145
R I++ + + K F++ T+ RTF AE+ + EW+Q
Sbjct: 364 KDAYSKRFISVACISHV---AAIGDQK--------FEVITNNRTFAFRAESDVERKEWMQ 412
Query: 146 SICQ 149
++ Q
Sbjct: 413 ALQQ 416
>gi|50234893 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1 [Homo
sapiens]
Length = 404
Score = 49.7 bits (117), Expect = 7e-06
Identities = 27/94 (28%), Positives = 52/94 (55%), Gaps = 23/94 (24%)
Query: 60 WRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNL------CEQLDVDVTLNFNKK 113
W++R+F L D + + Y+K++ K+PLR I L C+Q D+
Sbjct: 208 WKRRYFQL-------DENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDI--------- 251
Query: 114 EIQKGYMFDIKTSERTFYLVAETREDMNEWVQSI 147
+ + +F+I T+ RTFY+ A++ E+M+ W++++
Sbjct: 252 -MMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAV 284
>gi|31377720 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1 [Homo
sapiens]
Length = 404
Score = 49.7 bits (117), Expect = 7e-06
Identities = 27/94 (28%), Positives = 52/94 (55%), Gaps = 23/94 (24%)
Query: 60 WRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNL------CEQLDVDVTLNFNKK 113
W++R+F L D + + Y+K++ K+PLR I L C+Q D+
Sbjct: 208 WKRRYFQL-------DENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDI--------- 251
Query: 114 EIQKGYMFDIKTSERTFYLVAETREDMNEWVQSI 147
+ + +F+I T+ RTFY+ A++ E+M+ W++++
Sbjct: 252 -MMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAV 284
>gi|156616273 pleckstrin [Homo sapiens]
Length = 350
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/111 (31%), Positives = 55/111 (49%), Gaps = 12/111 (10%)
Query: 38 GHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLN 97
G ++ G L K +K W+ R FILR DP L YY G++ PL I+L
Sbjct: 243 GVIIKQGCLLKQGHRRK----NWKVRKFILRE-----DPAYLHYYDPAGAEDPLGAIHLR 293
Query: 98 LCEQLDVDVTLNFNKKEIQKGYMFDIKTSERT-FYLVAETREDMNEWVQSI 147
C V+ N K E + +F+I T++ ++L A T ++ EW+++I
Sbjct: 294 GCVVTSVESNSNGRKSEEEN--LFEIITADEVHYFLQAATPKERTEWIRAI 342
>gi|158631203 dual adaptor of phosphotyrosine and
3-phosphoinositides [Homo sapiens]
Length = 280
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 24/111 (21%)
Query: 35 TRSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTI 94
T+ G++ G L K+ W+ RWF L R + L+Y+K+ S +P+R +
Sbjct: 166 TKEGYLTKQGGLVKT----------WKTRWFTLHRNE-------LKYFKDQMSPEPIRIL 208
Query: 95 NLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQ 145
+L C + D ++++ + F + RTFYL A+T + +EW++
Sbjct: 209 DLTECSAVQFD----YSQERVN---CFCLVFPFRTFYLCAKTGVEADEWIK 252
>gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Homo
sapiens]
Length = 1034
Score = 45.8 bits (107), Expect = 1e-04
Identities = 50/209 (23%), Positives = 79/209 (37%), Gaps = 20/209 (9%)
Query: 44 GWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLD 103
GWL K K W+K WF+L+ L +Y N+ +K I+L +
Sbjct: 575 GWLWKKKDAKSYFSQKWKKYWFVLKDAS-------LYWYINEEDEKAEGFISL---PEFK 624
Query: 104 VDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQI-CGFRQEESTGFL 162
+D KK K IK +FY AE +DMN W+ I + G+ + E
Sbjct: 625 IDRASECRKKYAFKACHPKIK----SFYFAAEHLDDMNRWLNRINMLTAGYAERERIKQE 680
Query: 163 GNI-SSASHGLCSSPAEPSCSHQHLPQEQEPTSEPPVSHCVPPTWPIPAPPGCLRSHQHA 221
+ S + +P+ P P + P PP C P + A L S + +
Sbjct: 681 QDYWSESDKEEADTPSTPKQDSPPPPYDTYP--RPPSMSCASPY--VEAKHSRLSSTETS 736
Query: 222 SQRAEHARSASFSQGSEAPFIMRRNTAMQ 250
++ H GS A +R+ + +
Sbjct: 737 QSQSSHEEFRQEVTGSSAVSPIRKTASQR 765
>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
Length = 1242
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 22/137 (16%)
Query: 44 GWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKND-----GSKKPLRTINLNL 98
G+LRK + KR+F+LR + P LEYY+N+ S P R+I L
Sbjct: 17 GYLRKPK--------SMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLES 68
Query: 99 CEQLDVDVTLNFNKKEIQKG-YMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEE 157
C N NK+ K ++ + T + F + A++ + + W Q++ Q+ +
Sbjct: 69 C--------FNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH 120
Query: 158 STGFLGNISSASHGLCS 174
G + G CS
Sbjct: 121 HDGAAALGAGGGGGSCS 137
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 22/128 (17%)
Query: 30 PAGGSTRSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKK 89
P G R + + GWLRK K W RWF+L+ Q L Y+K++ K
Sbjct: 11 PQQGQGRQ-NAIKCGWLRKQGGFVK----TWHTRWFVLKGDQ-------LYYFKDEDETK 58
Query: 90 PLRTINL-------NLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNE 142
PL TI L + C + + F + + G + + ++ L+A T+ DM +
Sbjct: 59 PLGTIFLPGNKVSEHPCNEENPG---KFLFEVVPGGDRDRMTANHESYLLMASTQNDMED 115
Query: 143 WVQSICQI 150
WV+SI ++
Sbjct: 116 WVKSIRRV 123
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 17/121 (14%)
Query: 36 RSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTIN 95
R G VL +GWL+K K W++RWF+LR Q L YYK+ KP I+
Sbjct: 34 RLGPVLKAGWLKKQRSIMK----NWQQRWFVLRGDQ-------LFYYKDKDEIKPQGFIS 82
Query: 96 LNLCEQLDVDVTLNFNKKEIQK------GYMFDIKTSERTFYLVAETREDMNEWVQSICQ 149
L + ++ K + + G + + L+A ++ DM +WVQ+I +
Sbjct: 83 LQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRR 142
Query: 150 I 150
+
Sbjct: 143 V 143
>gi|46391075 hypothetical protein LOC79949 [Homo sapiens]
Length = 363
Score = 44.3 bits (103), Expect = 3e-04
Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 35/172 (20%)
Query: 48 KSPPEKKLR-LFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDV 106
KSPP + + +W+KR+FIL + S L YYK+ + +I ++ ++V +
Sbjct: 29 KSPPSQLFSSVTSWKKRFFILSKAGEKSFS--LSYYKDHHHRG---SIEIDQNSSVEVGI 83
Query: 107 TLNFNKKEIQKGY------MFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQE---- 156
+ + +QK + + I+T+ R ++L+ RE + +WV + FRQ+
Sbjct: 84 SSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSF---MSSFRQDIKAT 140
Query: 157 ----ESTGFLGN------------ISSASHGLCSSPAEPSCSHQHLPQEQEP 192
E LGN SS S + SS +HL ++ P
Sbjct: 141 QQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSP 192
>gi|55741447 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 1 [Homo sapiens]
Length = 1364
Score = 43.9 bits (102), Expect = 4e-04
Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 29/108 (26%)
Query: 43 SGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYK--NDGSKKPLRTINLNLCE 100
SG+L K + K W++RWF+LR+GQ + YYK +D +KP ++LN
Sbjct: 582 SGYLLKMGSQVK----TWKRRWFVLRQGQ-------IMYYKSPSDVIRKPQGQVDLN--- 627
Query: 101 QLDVDVTLNFNKKEIQKG---YMFDIKTSERTFYLVAETREDMNEWVQ 145
++ +I +G F + + ++T+YL A++ + EW++
Sbjct: 628 ----------SRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIR 665
>gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1
[Homo sapiens]
Length = 438
Score = 43.1 bits (100), Expect = 7e-04
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 22/168 (13%)
Query: 38 GHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLN 97
GH GWL K + W+K W IL+ L +Y N ++K +NL
Sbjct: 41 GHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSS-------LYWYSNQMAEKADGFVNL- 92
Query: 98 LCEQLDVDVTLNFNKKEIQKGYMFDIKTSE-RTFYLVAETREDMNEWVQSICQICGFRQE 156
D T+ E +K + F I + +TFY AE ++MN W+ + QE
Sbjct: 93 ------PDFTVE-RASECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAV-IHQE 144
Query: 157 ESTGFLGNISSASHG----LCSSPAEPSCSH-QHLPQEQEPTSEPPVS 199
+T S + +P P S Q L +Q +S P +S
Sbjct: 145 STTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTAQQASSSSPSLS 192
>gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1
[Homo sapiens]
Length = 438
Score = 43.1 bits (100), Expect = 7e-04
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 22/168 (13%)
Query: 38 GHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLN 97
GH GWL K + W+K W IL+ L +Y N ++K +NL
Sbjct: 41 GHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSS-------LYWYSNQMAEKADGFVNL- 92
Query: 98 LCEQLDVDVTLNFNKKEIQKGYMFDIKTSE-RTFYLVAETREDMNEWVQSICQICGFRQE 156
D T+ E +K + F I + +TFY AE ++MN W+ + QE
Sbjct: 93 ------PDFTVE-RASECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAV-IHQE 144
Query: 157 ESTGFLGNISSASHG----LCSSPAEPSCSH-QHLPQEQEPTSEPPVS 199
+T S + +P P S Q L +Q +S P +S
Sbjct: 145 STTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTAQQASSSSPSLS 192
>gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [Homo
sapiens]
Length = 437
Score = 43.1 bits (100), Expect = 7e-04
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 22/168 (13%)
Query: 38 GHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLN 97
GH GWL K + W+K W IL+ L +Y N ++K +NL
Sbjct: 40 GHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSS-------LYWYSNQMAEKADGFVNL- 91
Query: 98 LCEQLDVDVTLNFNKKEIQKGYMFDIKTSE-RTFYLVAETREDMNEWVQSICQICGFRQE 156
D T+ E +K + F I + +TFY AE ++MN W+ + QE
Sbjct: 92 ------PDFTVE-RASECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAV-IHQE 143
Query: 157 ESTGFLGNISSASHG----LCSSPAEPSCSH-QHLPQEQEPTSEPPVS 199
+T S + +P P S Q L +Q +S P +S
Sbjct: 144 STTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTAQQASSSSPSLS 191
>gi|197313732 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 43.1 bits (100), Expect = 7e-04
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 56 RLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEI 115
++ W+KRWF+ R + + YY + K I E++ D N NK
Sbjct: 1156 KIKTWKKRWFVFDRNKRT-----FSYYADKHETKLKGVIYFQAIEEVYYDHLKNANKSP- 1209
Query: 116 QKGYMFDIKTSERTFYLVAETREDMNEWVQSI 147
F +KT +R +Y+VA + E M W+ I
Sbjct: 1210 NPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVI 1241
>gi|197313730 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 43.1 bits (100), Expect = 7e-04
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 56 RLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEI 115
++ W+KRWF+ R + + YY + K I E++ D N NK
Sbjct: 1156 KIKTWKKRWFVFDRNKRT-----FSYYADKHETKLKGVIYFQAIEEVYYDHLKNANKSP- 1209
Query: 116 QKGYMFDIKTSERTFYLVAETREDMNEWVQSI 147
F +KT +R +Y+VA + E M W+ I
Sbjct: 1210 NPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVI 1241
>gi|197313728 pleckstrin homology-like domain, family B, member 2
isoform b [Homo sapiens]
Length = 1237
Score = 43.1 bits (100), Expect = 7e-04
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 56 RLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEI 115
++ W+KRWF+ R + + YY + K I E++ D N NK
Sbjct: 1140 KIKTWKKRWFVFDRNKRT-----FSYYADKHETKLKGVIYFQAIEEVYYDHLKNANKSP- 1193
Query: 116 QKGYMFDIKTSERTFYLVAETREDMNEWVQSI 147
F +KT +R +Y+VA + E M W+ I
Sbjct: 1194 NPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVI 1225
>gi|21955172 pleckstrin homology-like domain, family B, member 2
isoform c [Homo sapiens]
Length = 1210
Score = 43.1 bits (100), Expect = 7e-04
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 56 RLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEI 115
++ W+KRWF+ R + + YY + K I E++ D N NK
Sbjct: 1113 KIKTWKKRWFVFDRNKRT-----FSYYADKHETKLKGVIYFQAIEEVYYDHLKNANKSP- 1166
Query: 116 QKGYMFDIKTSERTFYLVAETREDMNEWVQSI 147
F +KT +R +Y+VA + E M W+ I
Sbjct: 1167 NPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVI 1198
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,916,496
Number of Sequences: 37866
Number of extensions: 1536969
Number of successful extensions: 6145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 5799
Number of HSP's gapped (non-prelim): 437
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.