Guide to the Human Genome
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Search of human proteins with 7706617

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706617 glycerophosphodiester phosphodiesterase 1 [Homo
sapiens]
         (331 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706617 glycerophosphodiester phosphodiesterase 1 [Homo sapiens]   687   0.0  
gi|21361649 osteoblast differentiation promoting factor protein ...    76   5e-14
gi|32698962 glycerophosphodiester phosphodiesterase domain conta...    59   6e-09
gi|189571657 glycerophosphodiester phosphodiesterase domain cont...    54   1e-07
gi|33457301 glycerophosphodiester phosphodiesterase domain conta...    53   4e-07
gi|25901062 hypothetical protein LOC56261 [Homo sapiens]               44   2e-04
gi|146198640 glycerophosphodiester phosphodiesterase domain cont...    44   2e-04
gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]      32   0.60 
gi|195972795 chemokine (C-C motif) receptor-like 2 isoform 2 [Ho...    32   0.78 
gi|68215224 chemokine (C-C motif) receptor-like 2 isoform 1 [Hom...    32   0.78 
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ...    30   3.0  
gi|21361910 zinc finger, DHHC domain containing 12 [Homo sapiens]      30   3.0  
gi|52317223 olfactory receptor, family 2, subfamily T, member 5 ...    30   3.9  
gi|52317217 olfactory receptor, family 2, subfamily T, member 29...    30   3.9  
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]                 29   5.1  
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]                 29   5.1  
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]                 29   5.1  
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]          29   5.1  
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]          29   5.1  
gi|17105394 ribosomal protein L23a [Homo sapiens]                      29   6.6  
gi|169206362 PREDICTED: similar to ribosomal protein L23a [Homo ...    28   8.7  

>gi|7706617 glycerophosphodiester phosphodiesterase 1 [Homo sapiens]
          Length = 331

 Score =  687 bits (1774), Expect = 0.0
 Identities = 331/331 (100%), Positives = 331/331 (100%)

Query: 1   MWLWEDQGGLLGPFSFLLLVLLLVTRSPVNACLLTGSLFVLLRVFSFEPVPSCRALQVLK 60
           MWLWEDQGGLLGPFSFLLLVLLLVTRSPVNACLLTGSLFVLLRVFSFEPVPSCRALQVLK
Sbjct: 1   MWLWEDQGGLLGPFSFLLLVLLLVTRSPVNACLLTGSLFVLLRVFSFEPVPSCRALQVLK 60

Query: 61  PRDRISAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTT 120
           PRDRISAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTT
Sbjct: 61  PRDRISAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTT 120

Query: 121 DGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLREAVAECLNHNLTIFFDVKGHAH 180
           DGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLREAVAECLNHNLTIFFDVKGHAH
Sbjct: 121 DGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLREAVAECLNHNLTIFFDVKGHAH 180

Query: 181 KATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPR 240
           KATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPR
Sbjct: 181 KATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPR 240

Query: 241 YDTFWKHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQVVGWT 300
           YDTFWKHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQVVGWT
Sbjct: 241 YDTFWKHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQVVGWT 300

Query: 301 VNTFDEKSYYESHLGSSYITDSMVEDCEPHF 331
           VNTFDEKSYYESHLGSSYITDSMVEDCEPHF
Sbjct: 301 VNTFDEKSYYESHLGSSYITDSMVEDCEPHF 331


>gi|21361649 osteoblast differentiation promoting factor protein
           [Homo sapiens]
          Length = 539

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 48/144 (33%), Positives = 75/144 (52%), Gaps = 25/144 (17%)

Query: 58  VLKPRD---RISAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDN 114
           +++PRD   +   + HRG    APENTL ++R+ A+ GAT  E D+  +SDG+P LMHD 
Sbjct: 214 IMEPRDLPPKPGLVGHRGAPMLAPENTLMSLRKTAECGATVFETDVMVSSDGVPFLMHDE 273

Query: 115 TVDRTTDG--------TGRLCDLTFEQIRKLNPAANHRLRNDF--------PDEK----- 153
            + RTT+         T    D ++ ++++LN  +    R  F        PD+K     
Sbjct: 274 HLSRTTNVASVFPTRITAHSSDFSWTELKRLNAGSWFLERRPFWGAKPLAGPDQKEAESQ 333

Query: 154 -IPTLREAVAECLNHNLTIFFDVK 176
            +P L E + E    NL+I FD++
Sbjct: 334 TVPALEELLEEAAALNLSIMFDLR 357


>gi|32698962 glycerophosphodiester phosphodiesterase domain
           containing 1 [Homo sapiens]
          Length = 314

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 63/253 (24%), Positives = 108/253 (42%), Gaps = 20/253 (7%)

Query: 68  IAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTTDGTGRLC 127
           I+HRGG+ +  ENT+AA + A K G   +ELD   T D   V+ HD  + R T     + 
Sbjct: 43  ISHRGGAGENLENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNIS 102

Query: 128 DLTF----EQIRKLNPAANHRLRNDFPDEKIPTLREAVAECLNHNLTIFFDVKGHA--HK 181
           DL +      + KL+ +     + +  D +IP L+E      N  + I   V  +    K
Sbjct: 103 DLKYCELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKK 162

Query: 182 ATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPRY 241
            +E +K+   E   ++ N+     + E  YK   +D  ++ +L      L     G   +
Sbjct: 163 VSELVKRYNREHLTVWGNANY--EIVEKCYK-ENSDIPILFSLQRVLLILGLFFTGLLPF 219

Query: 242 DTFWKHFIFVMMDILL-----DWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQV 296
               + F  + M  ++       +M     +L  +S  L+ +     A     +A+GIQV
Sbjct: 220 VPIREQFFEIPMPSIILKLKEPHTMSRSQKFLIWLSDLLLMR----KALFDHLTARGIQV 275

Query: 297 VGWTVNTFDEKSY 309
             W +N  +E+ Y
Sbjct: 276 YIWVLN--EEQEY 286


>gi|189571657 glycerophosphodiester phosphodiesterase domain
           containing 5 [Homo sapiens]
          Length = 605

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 30/78 (38%), Positives = 41/78 (52%)

Query: 68  IAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTTDGTGRLC 127
           I HRG    APE+TL + R+A +    G++ DI  + DG+P LMHD T+ RTT+      
Sbjct: 231 IGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFP 290

Query: 128 DLTFEQIRKLNPAANHRL 145
           +L       LN     RL
Sbjct: 291 ELARRPASMLNWTTLQRL 308


>gi|33457301 glycerophosphodiester phosphodiesterase domain
           containing 4 [Homo sapiens]
          Length = 520

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 6/89 (6%)

Query: 33  LLTGSLFVLLRVFSFEPVPSCRALQVLKPRDRISAIAHRGGSHDAPENTLAAIRQAAKNG 92
           +L G   + L ++S    P  +  + L P+  I    HRG     PENT+ +  +A ++G
Sbjct: 172 ILLGLYLMPLGIYS----PCIQEKENLGPKPTI--FGHRGAPMLGPENTMMSFEKAVEHG 225

Query: 93  ATGVELDIEFTSDGIPVLMHDNTVDRTTD 121
           A G+E DI  + D +P LMHD  + RTT+
Sbjct: 226 AHGLETDIHLSYDHVPFLMHDFDLKRTTN 254


>gi|25901062 hypothetical protein LOC56261 [Homo sapiens]
          Length = 672

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 9/64 (14%)

Query: 60  KPRDRISAIAHRGGSHDAP--------ENTLAAIRQAAKNGATGVELDIEFTSDGIPVLM 111
           KPR  +  + HRG  +           ENT+A++R AA +GA  VE D+  + D +PV+ 
Sbjct: 314 KPRIPLD-VGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVY 372

Query: 112 HDNT 115
           HD T
Sbjct: 373 HDLT 376


>gi|146198640 glycerophosphodiester phosphodiesterase domain
           containing 3 [Homo sapiens]
          Length = 318

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 25/74 (33%), Positives = 38/74 (51%)

Query: 61  PRDRISAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTT 120
           P  RI   AHRGGS +  ENT+ A+  +    +  +ELD + T D + V+ HD  + R +
Sbjct: 35  PTFRIRLGAHRGGSGELLENTMEAMENSMAQRSDLLELDCQLTRDRVVVVSHDENLCRQS 94

Query: 121 DGTGRLCDLTFEQI 134
                +  L FE +
Sbjct: 95  GLNRDVGSLDFEDL 108


>gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]
          Length = 1009

 Score = 32.3 bits (72), Expect = 0.60
 Identities = 30/137 (21%), Positives = 61/137 (44%), Gaps = 17/137 (12%)

Query: 143 HRLRNDFPDEKIPTLREAVAEC---LNHNLTIFFDVKGHAHKATEALKKMYMEFPQLYNN 199
           HR+  ++    +   REAV      LN    I+ D  G+     +  ++ Y+ +    NN
Sbjct: 698 HRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGY-----QMQRRPYVSY---VNN 749

Query: 200 SVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPR---YDTFWKHFIFVM-MDI 255
           S+  ++ P V     +  +  +  L+ R   +S  G+G+     +   W +F + +  ++
Sbjct: 750 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 809

Query: 256 LLDWS--MHNILWYLCG 270
            L+ +  +H +LW L G
Sbjct: 810 TLNDTSVVHPVLWLLLG 826


>gi|195972795 chemokine (C-C motif) receptor-like 2 isoform 2 [Homo
           sapiens]
          Length = 356

 Score = 32.0 bits (71), Expect = 0.78
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 200 SVVCSFLPE-VIYKMRQTDRDVITALTHRPWSLSHTGDGKPRYDTFWKHFIFVMMDI 255
           + + + LPE V+YK +  D+    A +  P+         P  +TFWKHF+ + M+I
Sbjct: 170 TAILATLPEFVVYKPQMEDQKYKCAFSRTPFL--------PADETFWKHFLTLKMNI 218


>gi|68215224 chemokine (C-C motif) receptor-like 2 isoform 1 [Homo
           sapiens]
          Length = 344

 Score = 32.0 bits (71), Expect = 0.78
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 200 SVVCSFLPE-VIYKMRQTDRDVITALTHRPWSLSHTGDGKPRYDTFWKHFIFVMMDI 255
           + + + LPE V+YK +  D+    A +  P+         P  +TFWKHF+ + M+I
Sbjct: 158 TAILATLPEFVVYKPQMEDQKYKCAFSRTPFL--------PADETFWKHFLTLKMNI 206


>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
           [Homo sapiens]
          Length = 386

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 8/93 (8%)

Query: 150 PDEKIPTLREAVAECLNHNLTIFFDVKGHAHKATEALKKMYMEFPQLYNNSVVCSFLPEV 209
           P +    + E ++E   +N+   F+V GH     +AL   +M     Y  SVV    P  
Sbjct: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMN----YGTSVVVGVPPSA 310

Query: 210 IYKMRQTDRDVITALTHRPWSLSHTGDGKPRYD 242
               +    D +   T R W     G  K R D
Sbjct: 311 ----KMLTYDPMLLFTGRTWKGCVFGGLKSRDD 339


>gi|21361910 zinc finger, DHHC domain containing 12 [Homo sapiens]
          Length = 267

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 14/46 (30%)

Query: 4  WEDQGGLLGPFSFLLLVLLLVTRSPVNACLLTGSLFVLLRVFSFEP 49
          WE+QG LL P +FLLLVL              GSL + L V   +P
Sbjct: 38 WEEQGELLLPLTFLLLVL--------------GSLLLYLAVSLMDP 69


>gi|52317223 olfactory receptor, family 2, subfamily T, member 5
           [Homo sapiens]
          Length = 315

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 16/101 (15%)

Query: 191 MEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTH-----RPWSLSHTGDGKPRYDTFW 245
           + +P L N+ V C FL    + +   D  ++T +T      R W + H          F+
Sbjct: 134 LRYPVLMNHRV-CLFLASGCWFLGSVDGFMLTPITMSFPFCRSWEIHH----------FF 182

Query: 246 KHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYL 286
                V +    D S++  L YLC +   L+    +S +YL
Sbjct: 183 CEVPAVTILSCSDTSLYETLMYLCCVLMLLIPVTIISSSYL 223


>gi|52317217 olfactory receptor, family 2, subfamily T, member 29
           [Homo sapiens]
          Length = 309

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 16/101 (15%)

Query: 191 MEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTH-----RPWSLSHTGDGKPRYDTFW 245
           + +P L N+ V C FL    + +   D  ++T +T      R W + H          F+
Sbjct: 128 LRYPVLMNHRV-CLFLASGCWFLGSVDGFMLTPITMSFPFCRSWEIHH----------FF 176

Query: 246 KHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYL 286
                V +    D S++  L YLC +   L+    +S +YL
Sbjct: 177 CEVPAVTILSCSDTSLYETLMYLCCVLMLLIPVTIISSSYL 217


>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
          Length = 1260

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 99  DIEFTSDGIPVLMHDNTVDRTTDGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLR 158
           D E  S+ + V     TVD      G LCD   + I +L      R   +  + KI  LR
Sbjct: 848 DKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKINKLR 907

Query: 159 EAV---AECLNHNLTIFFDVKGHAH 180
             V    E ++    I+ D    AH
Sbjct: 908 NKVNWKTEIISEMNQIYEDNDKDAH 932


>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
          Length = 1265

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 99  DIEFTSDGIPVLMHDNTVDRTTDGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLR 158
           D E  S+ + V     TVD      G LCD   + I +L      R   +  + KI  LR
Sbjct: 848 DKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKINKLR 907

Query: 159 EAV---AECLNHNLTIFFDVKGHAH 180
             V    E ++    I+ D    AH
Sbjct: 908 NKVNWKTEIISEMNQIYEDNDKDAH 932


>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
          Length = 1261

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 99  DIEFTSDGIPVLMHDNTVDRTTDGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLR 158
           D E  S+ + V     TVD      G LCD   + I +L      R   +  + KI  LR
Sbjct: 848 DKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILELKKYVTDRKSAEQNESKINKLR 907

Query: 159 EAV---AECLNHNLTIFFDVKGHAH 180
             V    E ++    I+ D    AH
Sbjct: 908 NKVNWKTEIISEMNQIYEDNDKDAH 932


>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
          Length = 1291

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 14/44 (31%), Positives = 24/44 (54%)

Query: 73  GSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTV 116
           G   + E++L A  +  + G   +ELD     DG+PV+ H +T+
Sbjct: 341 GDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTL 384


>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
          Length = 1290

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 14/44 (31%), Positives = 24/44 (54%)

Query: 73  GSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTV 116
           G   + E++L A  +  + G   +ELD     DG+PV+ H +T+
Sbjct: 341 GDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTL 384


>gi|17105394 ribosomal protein L23a [Homo sapiens]
          Length = 156

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 2/40 (5%)

Query: 153 KIPTLREAVAECLNHNLTIFF--DVKGHAHKATEALKKMY 190
           K P   E+  + +  N T+ F  DVK + H+  +A+KK+Y
Sbjct: 78  KFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLY 117


>gi|169206362 PREDICTED: similar to ribosomal protein L23a [Homo
           sapiens]
          Length = 152

 Score = 28.5 bits (62), Expect = 8.7
 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 148 DFPDEKIPTLREAVAECLNHNLTIFF--DVKGHAHKATEALKKMY 190
           D+   K P   E+  +    N T+ F  DVK   H+  +A+KK+Y
Sbjct: 63  DYAIIKFPLTAESAVKKTEENNTLVFTVDVKAKKHQIRQAVKKLY 107


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,054,894
Number of Sequences: 37866
Number of extensions: 577678
Number of successful extensions: 1463
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1442
Number of HSP's gapped (non-prelim): 28
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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