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Search of human proteins with 7706497
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
(228 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens] 458 e-129
gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens] 338 2e-93
gi|4502011 adenylate kinase 1 [Homo sapiens] 156 1e-38
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 132 2e-31
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 132 2e-31
gi|4502013 adenylate kinase 2 isoform a [Homo sapiens] 95 4e-20
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens] 95 4e-20
gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens] 82 3e-16
gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens] 82 3e-16
gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens] 82 3e-16
gi|19923437 adenylate kinase 3 [Homo sapiens] 75 4e-14
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 51 7e-07
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo... 48 6e-06
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo... 37 0.018
gi|45356151 non-SMC condensin II complex, subunit D3 [Homo sapiens] 34 0.090
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 33 0.26
gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo s... 31 1.00
gi|18699734 uridine-cytidine kinase 2 [Homo sapiens] 30 1.3
gi|7706212 TAF9 RNA polymerase II, TATA box binding protein-asso... 30 1.7
gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p5... 30 1.7
gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p5... 30 1.7
gi|31543419 polynucleotide kinase 3' phosphatase [Homo sapiens] 30 2.2
gi|145580600 schlafen family member 5 [Homo sapiens] 29 2.9
gi|62865612 TAF9 RNA polymerase II, TATA box binding protein-ass... 29 3.8
gi|33300633 cleavage and polyadenylation specific factor 3-like ... 28 5.0
gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 28 6.5
gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 28 6.5
gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 28 6.5
gi|13569934 sperm acrosome associated 1 [Homo sapiens] 28 6.5
gi|148727333 adenylate kinase 7 [Homo sapiens] 28 6.5
>gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
Length = 228
Score = 458 bits (1178), Expect = e-129
Identities = 228/228 (100%), Positives = 228/228 (100%)
Query: 1 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG 60
MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG
Sbjct: 1 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG 60
Query: 61 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK 120
YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK
Sbjct: 61 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK 120
Query: 121 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 180
FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL
Sbjct: 121 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 180
Query: 181 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 228
EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG
Sbjct: 181 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 228
>gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens]
Length = 179
Score = 338 bits (868), Expect = 2e-93
Identities = 179/228 (78%), Positives = 179/228 (78%), Gaps = 49/228 (21%)
Query: 1 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG 60
MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVE
Sbjct: 1 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVE--- 57
Query: 61 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK 120
EMDQTMAANAQKNK
Sbjct: 58 ----------------------------------------------EMDQTMAANAQKNK 71
Query: 121 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 180
FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL
Sbjct: 72 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 131
Query: 181 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 228
EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG
Sbjct: 132 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 179
>gi|4502011 adenylate kinase 1 [Homo sapiens]
Length = 194
Score = 156 bits (395), Expect = 1e-38
Identities = 79/196 (40%), Positives = 129/196 (65%), Gaps = 9/196 (4%)
Query: 31 RLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIK 90
+L K ++FV+GGPG+GKGTQC +IV+KYGYTHLS G+LLR E + ++ G+ + + ++
Sbjct: 4 KLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSAR-GKKLSEIME 62
Query: 91 EGKIVPVEITISLLKREMDQTMAANAQKNK-FLIDGFPRNQDNLQGWNKTMDGKADVSFV 149
+G++VP+E + +L+ M A +K FLIDG+PR + + + + + +
Sbjct: 63 KGQLVPLETVLDMLR----DAMVAKVNTSKGFLIDGYPREVQQGEEFERRI---GQPTLL 115
Query: 150 LFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDA 209
L+ D E +R L+RG++SGR DDN E+++KR++TY ++T+P+I YE+ G V+K++A
Sbjct: 116 LYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNA 175
Query: 210 SKSVDEVFDEVVQIFD 225
SVD VF +V D
Sbjct: 176 EGSVDSVFSQVCTHLD 191
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 132 bits (333), Expect = 2e-31
Identities = 71/194 (36%), Positives = 117/194 (60%), Gaps = 7/194 (3%)
Query: 32 LMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKE 91
L K ++F++GGPG+GKGTQC ++VEKYG+THLS GELLR+E + +S+ +LI ++
Sbjct: 373 LRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS-ESERSKLIRDIMER 431
Query: 92 GKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLF 151
G +VP I + LLK M +A+ FLIDG+PR + + + + D V+
Sbjct: 432 GDLVPSGIVLELLKEAM---VASLGDTRGFLIDGYPREVKQGEEFGRRI---GDPQLVIC 485
Query: 152 FDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASK 211
DC+ + R L+R +SS DD +++ KR++ Y +++ P+I YE ++ KI+A
Sbjct: 486 MDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEG 545
Query: 212 SVDEVFDEVVQIFD 225
+ ++VF ++ D
Sbjct: 546 TPEDVFLQLCTAID 559
Score = 121 bits (304), Expect = 4e-28
Identities = 66/199 (33%), Positives = 110/199 (55%), Gaps = 8/199 (4%)
Query: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDS-QYGELIEKY 88
P +P ++ V+GGPG+GKGTQ +I E+YG+ ++S GELLR + + S + LI K
Sbjct: 127 PTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKI 186
Query: 89 IKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSF 148
I G++ P E TI+ +K+++ Q + +IDGFPR+ + D
Sbjct: 187 ITTGELAPQETTITEIKQKLMQI----PDEEGIVIDGFPRDVAQALSFE---DQICTPDL 239
Query: 149 VLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKID 208
V+F C N+ ER L+R + GR DDN ++ ++R+ + Q+ P++ ++E G + D
Sbjct: 240 VVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFD 299
Query: 209 ASKSVDEVFDEVVQIFDKE 227
A + DEVF ++ D +
Sbjct: 300 ADRDEDEVFYDISMAVDNK 318
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 132 bits (333), Expect = 2e-31
Identities = 71/194 (36%), Positives = 117/194 (60%), Gaps = 7/194 (3%)
Query: 32 LMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKE 91
L K ++F++GGPG+GKGTQC ++VEKYG+THLS GELLR+E + +S+ +LI ++
Sbjct: 347 LRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS-ESERSKLIRDIMER 405
Query: 92 GKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLF 151
G +VP I + LLK M +A+ FLIDG+PR + + + + D V+
Sbjct: 406 GDLVPSGIVLELLKEAM---VASLGDTRGFLIDGYPREVKQGEEFGRRI---GDPQLVIC 459
Query: 152 FDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASK 211
DC+ + R L+R +SS DD +++ KR++ Y +++ P+I YE ++ KI+A
Sbjct: 460 MDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEG 519
Query: 212 SVDEVFDEVVQIFD 225
+ ++VF ++ D
Sbjct: 520 TPEDVFLQLCTAID 533
Score = 121 bits (304), Expect = 4e-28
Identities = 66/199 (33%), Positives = 110/199 (55%), Gaps = 8/199 (4%)
Query: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDS-QYGELIEKY 88
P +P ++ V+GGPG+GKGTQ +I E+YG+ ++S GELLR + + S + LI K
Sbjct: 101 PTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKI 160
Query: 89 IKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSF 148
I G++ P E TI+ +K+++ Q + +IDGFPR+ + D
Sbjct: 161 ITTGELAPQETTITEIKQKLMQI----PDEEGIVIDGFPRDVAQALSFE---DQICTPDL 213
Query: 149 VLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKID 208
V+F C N+ ER L+R + GR DDN ++ ++R+ + Q+ P++ ++E G + D
Sbjct: 214 VVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFD 273
Query: 209 ASKSVDEVFDEVVQIFDKE 227
A + DEVF ++ D +
Sbjct: 274 ADRDEDEVFYDISMAVDNK 292
>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
Length = 239
Score = 95.1 bits (235), Expect = 4e-20
Identities = 67/225 (29%), Positives = 108/225 (48%), Gaps = 33/225 (14%)
Query: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYI 89
P K + +LG PGAGKGTQ R+ E + HL+ G++LR S+ G+ ++ +
Sbjct: 10 PEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLR-AMVASGSELGKKLKATM 68
Query: 90 KEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMD-GKADVSF 148
GK+V E+ + L+++ ++ + KN FL+DGFPR + + M+ K +
Sbjct: 69 DAGKLVSDEMVVELIEKNLETPLC----KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDS 124
Query: 149 VLFFDCNNEICIERCLER------GKS---------------------SGRSDDNRESLE 181
V+ F + + I R R G+S RSDDN ++L+
Sbjct: 125 VIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALK 184
Query: 182 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDK 226
R+Q Y T P+I+ Y + G IDAS++ D VF ++ F K
Sbjct: 185 IRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
Length = 232
Score = 95.1 bits (235), Expect = 4e-20
Identities = 67/225 (29%), Positives = 108/225 (48%), Gaps = 33/225 (14%)
Query: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYI 89
P K + +LG PGAGKGTQ R+ E + HL+ G++LR S+ G+ ++ +
Sbjct: 10 PEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLR-AMVASGSELGKKLKATM 68
Query: 90 KEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMD-GKADVSF 148
GK+V E+ + L+++ ++ + KN FL+DGFPR + + M+ K +
Sbjct: 69 DAGKLVSDEMVVELIEKNLETPLC----KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDS 124
Query: 149 VLFFDCNNEICIERCLER------GKS---------------------SGRSDDNRESLE 181
V+ F + + I R R G+S RSDDN ++L+
Sbjct: 125 VIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALK 184
Query: 182 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDK 226
R+Q Y T P+I+ Y + G IDAS++ D VF ++ F K
Sbjct: 185 IRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
>gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens]
Length = 223
Score = 82.4 bits (202), Expect = 3e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 38/221 (17%)
Query: 34 KPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGK 93
K L +LG PG+GKGT C RI + +G HLS+G LR+ K ++ GE+ ++YI++
Sbjct: 4 KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIK-ASTEVGEMAKQYIEKSL 62
Query: 94 IVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFD 153
+VP + L+ E++ N + +L+DGFPR G + +D +V V+ +
Sbjct: 63 LVPDHVITRLMMSELE-----NRRGQHWLLDGFPRT----LGQAEALDKICEVDLVISLN 113
Query: 154 CNNEICIERCLER--GKSSGR-------------------------SDDNRESLEKRIQT 186
E +R R SGR DD E++ R++
Sbjct: 114 IPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQ 173
Query: 187 YLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKE 227
Y KP+I+LY+ G + + +++ ++++ V +F +
Sbjct: 174 YKDVAKPVIELYKSRGVLHQFSGTET-NKIWPYVYTLFSNK 213
>gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens]
Length = 223
Score = 82.4 bits (202), Expect = 3e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 38/221 (17%)
Query: 34 KPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGK 93
K L +LG PG+GKGT C RI + +G HLS+G LR+ K ++ GE+ ++YI++
Sbjct: 4 KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIK-ASTEVGEMAKQYIEKSL 62
Query: 94 IVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFD 153
+VP + L+ E++ N + +L+DGFPR G + +D +V V+ +
Sbjct: 63 LVPDHVITRLMMSELE-----NRRGQHWLLDGFPRT----LGQAEALDKICEVDLVISLN 113
Query: 154 CNNEICIERCLER--GKSSGR-------------------------SDDNRESLEKRIQT 186
E +R R SGR DD E++ R++
Sbjct: 114 IPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQ 173
Query: 187 YLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKE 227
Y KP+I+LY+ G + + +++ ++++ V +F +
Sbjct: 174 YKDVAKPVIELYKSRGVLHQFSGTET-NKIWPYVYTLFSNK 213
>gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens]
Length = 223
Score = 82.4 bits (202), Expect = 3e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 38/221 (17%)
Query: 34 KPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGK 93
K L +LG PG+GKGT C RI + +G HLS+G LR+ K ++ GE+ ++YI++
Sbjct: 4 KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIK-ASTEVGEMAKQYIEKSL 62
Query: 94 IVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFD 153
+VP + L+ E++ N + +L+DGFPR G + +D +V V+ +
Sbjct: 63 LVPDHVITRLMMSELE-----NRRGQHWLLDGFPRT----LGQAEALDKICEVDLVISLN 113
Query: 154 CNNEICIERCLER--GKSSGR-------------------------SDDNRESLEKRIQT 186
E +R R SGR DD E++ R++
Sbjct: 114 IPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQ 173
Query: 187 YLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKE 227
Y KP+I+LY+ G + + +++ ++++ V +F +
Sbjct: 174 YKDVAKPVIELYKSRGVLHQFSGTET-NKIWPYVYTLFSNK 213
>gi|19923437 adenylate kinase 3 [Homo sapiens]
Length = 227
Score = 75.5 bits (184), Expect = 4e-14
Identities = 54/211 (25%), Positives = 99/211 (46%), Gaps = 40/211 (18%)
Query: 29 SPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKY 88
S RL++ ++ +G PG+GKGT +RI + HLS+G+LLRD ++ G L + +
Sbjct: 4 SARLLRAVI---MGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLR-GTEIGVLAKAF 59
Query: 89 IKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSF 148
I +GK++P ++ L E+ N + +L+DGFPR + +D +
Sbjct: 60 IDQGKLIPDDVMTRLALHEL-----KNLTQYSWLLDGFPRTLPQAE----ALDRAYQIDT 110
Query: 149 VLFFDCNNEICIERCLER--GKSSG-------------------------RSDDNRESLE 181
V+ + E+ +R R +SG R DD E++
Sbjct: 111 VINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVI 170
Query: 182 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKS 212
KR++ Y TKP+++ Y++ G ++ +++
Sbjct: 171 KRLKAYEDQTKPVLEYYQKKGVLETFSGTET 201
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 51.2 bits (121), Expect = 7e-07
Identities = 33/125 (26%), Positives = 65/125 (52%), Gaps = 12/125 (9%)
Query: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKN-PDSQYGELIEKY 88
P+ P+ + ++G P +GK T +I +YG HLS G LR N P+++ ++ +
Sbjct: 1406 PKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWH 1465
Query: 89 IKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFP--RNQDNLQGWNKTMDGKADV 146
+ +G P E+ I L+ + +++ A +IDG+P ++Q NL ++ ++ +
Sbjct: 1466 LHKGMTAPDELAIQALELSLMESVCNTA---GVVIDGYPVTKHQMNL------LEARSII 1516
Query: 147 SFVLF 151
V+F
Sbjct: 1517 PMVIF 1521
Score = 36.6 bits (83), Expect = 0.018
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Query: 32 LMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKE 91
L KP+ V G PG GK T I + + + A +L +E+ +++ G +++ +
Sbjct: 27 LSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPIL-EEQIAAETESGVMLQSMLIS 85
Query: 92 GKIVPVEITISLLKREMD 109
G+ +P E+ I L+ +++
Sbjct: 86 GQSIPDELVIKLMLEKLN 103
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Query: 17 FLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKN 76
FLL R P LL P P VF+LG +GK T C + E Y + +L++
Sbjct: 375 FLLNPR-PYLL-PPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVVDYAQLVQPRF-- 430
Query: 77 PDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKF 121
D L+E I E +++ L RE+ A +F
Sbjct: 431 -DKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREF 474
>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
sapiens]
Length = 479
Score = 48.1 bits (113), Expect = 6e-06
Identities = 28/101 (27%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
Query: 38 VFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPV 97
V +LG G+GK Q A + +KY ++ G+LL+ E + +GELI+ + ++ VP
Sbjct: 271 VLLLGPVGSGKSLQAALLAQKYRLVNVCCGQLLK-EAVADRTTFGELIQPFFEKEMAVPD 329
Query: 98 EITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNK 138
+ + +L + +DQ + + +++ G PR+ D N+
Sbjct: 330 SLLMKVLSQRLDQ---QDCIQKGWVLHGVPRDLDQAHLLNR 367
>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
sapiens]
Length = 421
Score = 36.6 bits (83), Expect = 0.018
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Query: 32 LMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKE 91
L KP+ V G PG GK T I + + + A +L +E+ +++ G +++ +
Sbjct: 27 LSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPIL-EEQIAAETESGVMLQSMLIS 85
Query: 92 GKIVPVEITISLLKREMD 109
G+ +P E+ I L+ +++
Sbjct: 86 GQSIPDELVIKLMLEKLN 103
Score = 27.7 bits (60), Expect = 8.5
Identities = 19/43 (44%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 17 FLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKY 59
FLL R P LL P P VF+LG +GK T C + E Y
Sbjct: 375 FLLNPR-PYLL-PPMPGPPCKVFILGPQYSGKTTLCNMLAENY 415
>gi|45356151 non-SMC condensin II complex, subunit D3 [Homo sapiens]
Length = 1498
Score = 34.3 bits (77), Expect = 0.090
Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 13/85 (15%)
Query: 52 CARIVEKYGYTHLSAGELLRDERKNPDSQYGELIE---KYIKEGKI----VPVEITISLL 104
CA++V+K Y +A L++ K P +Y I KY + KI +++ ++LL
Sbjct: 361 CAKVVDKSEYRTFAAQSLVQLLSKLPCGEYAMFIAWLYKYSRSSKIPHRVFTLDVVLALL 420
Query: 105 ---KREMDQTMAANAQ---KNKFLI 123
+RE+D T++ Q K+KFL+
Sbjct: 421 ELPEREVDNTLSLEHQKFLKHKFLV 445
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 32.7 bits (73), Expect = 0.26
Identities = 41/202 (20%), Positives = 88/202 (43%), Gaps = 24/202 (11%)
Query: 41 LGGPGAGKGTQCARIVEKYGYTHLSAGE-----LLRDER-------------KNPDSQYG 82
LG G G QC + E Y YTH A E ++ +E K P +
Sbjct: 132 LGFGGWGSAGQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEAADVFCVTCKTPIRAFQ 191
Query: 83 ELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDG 142
++ +++ KE +++P+ + K E+ + M +K ++ F + + + + G
Sbjct: 192 KVFDEH-KEHEVIPLNEALESAKDEIHKNM-YKLEKQIIEMENFANHLEEVFITVEENFG 249
Query: 143 KADVSFVLFFDCNNEICIERCLERGKSSG-RSDDNRESLEKRIQT---YLQSTKPIIDLY 198
K + +F ++ E ++ E+ ++ G + + E+L ++ + L + K +++
Sbjct: 250 KQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELMETI 309
Query: 199 EEMGKVKKIDASKSVDEVFDEV 220
EEM +K+D K + D +
Sbjct: 310 EEMCHEEKVDFIKDAVAMADRL 331
>gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo
sapiens]
Length = 212
Score = 30.8 bits (68), Expect = 1.00
Identities = 45/197 (22%), Positives = 83/197 (42%), Gaps = 26/197 (13%)
Query: 37 VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVP 96
++ + G AGK TQ ++VE A ELLR ++ ++ G+L+ Y+++ V
Sbjct: 8 LIVLEGVDRAGKSTQSRKLVEALCAAGHRA-ELLRFPERS--TEIGKLLSSYLQKKSDVE 64
Query: 97 ---VEITIS--------LLKREMDQTMAANAQKNKFLIDGFPRNQDNLQ-GWNKTMD-GK 143
V + S L+K ++ Q + + F F ++N W K D G
Sbjct: 65 DHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQPDVGL 124
Query: 144 ADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGK 203
VLF ++ + +RG +N E+ ++ + Q K +
Sbjct: 125 PKPDLVLFL----QLQLADAAKRGAFGHERYENGAFQERALRCFHQLMK------DTTLN 174
Query: 204 VKKIDASKSVDEVFDEV 220
K +DASKS++ V +++
Sbjct: 175 WKMVDASKSIEAVHEDI 191
>gi|18699734 uridine-cytidine kinase 2 [Homo sapiens]
Length = 261
Score = 30.4 bits (67), Expect = 1.3
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 27/93 (29%)
Query: 34 KPLVVFVLGGPGAGKGTQCARIVEKYGYTHL-------------SAGELLRDERK----- 75
+P ++ V GG +GK + CA+IV+ G + S +L E+K
Sbjct: 19 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALK 78
Query: 76 ------NPDSQYGELIEKYIK---EGKIVPVEI 99
+PD+ ELI K +K EGK V + +
Sbjct: 79 GQFNFDHPDAFDNELILKTLKEITEGKTVQIPV 111
>gi|7706212 TAF9 RNA polymerase II, TATA box binding
protein-associated factor isoform b [Homo sapiens]
Length = 172
Score = 30.0 bits (66), Expect = 1.7
Identities = 12/37 (32%), Positives = 21/37 (56%)
Query: 38 VFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDER 74
+ + G PG GK T + K G +++ G+L R+E+
Sbjct: 6 ILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREEQ 42
>gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
gamma) [Homo sapiens]
Length = 461
Score = 30.0 bits (66), Expect = 1.7
Identities = 16/59 (27%), Positives = 35/59 (59%), Gaps = 5/59 (8%)
Query: 174 DDNRESLEKRIQTY----LQSTKPIIDLYEEMGKV-KKIDASKSVDEVFDEVVQIFDKE 227
+DN +++ K++Q Y + +K LYEE + ++I ++ E F+E ++IF+++
Sbjct: 171 EDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQ 229
>gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
gamma) [Homo sapiens]
Length = 461
Score = 30.0 bits (66), Expect = 1.7
Identities = 16/59 (27%), Positives = 35/59 (59%), Gaps = 5/59 (8%)
Query: 174 DDNRESLEKRIQTY----LQSTKPIIDLYEEMGKV-KKIDASKSVDEVFDEVVQIFDKE 227
+DN +++ K++Q Y + +K LYEE + ++I ++ E F+E ++IF+++
Sbjct: 171 EDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQ 229
>gi|31543419 polynucleotide kinase 3' phosphatase [Homo sapiens]
Length = 521
Score = 29.6 bits (65), Expect = 2.2
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 35 PLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKI 94
P VV +G PGAGK T + + GY H++ L +R E +K+GK
Sbjct: 365 PEVVVAVGFPGAGKSTFLKKHLVSAGYVHVNRDTLGSWQR------CVTTCETALKQGKR 418
Query: 95 VPVEIT 100
V ++ T
Sbjct: 419 VAIDNT 424
>gi|145580600 schlafen family member 5 [Homo sapiens]
Length = 891
Score = 29.3 bits (64), Expect = 2.9
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 6 RSGLLHVLGLSFL-LQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEK 58
+S L LG L L T + L S L K +FV G PG+GK RI+EK
Sbjct: 541 KSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEK 594
>gi|62865612 TAF9 RNA polymerase II, TATA box binding
protein-associated factor isoform c [Homo sapiens]
Length = 169
Score = 28.9 bits (63), Expect = 3.8
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 42 GGPGAGKGTQCARIVEKYGYTHLSAGELLRDER 74
G PG GK T + K G +++ G+L R+E+
Sbjct: 7 GTPGVGKTTLGKELASKSGLKYINVGDLAREEQ 39
>gi|33300633 cleavage and polyadenylation specific factor 3-like
[Homo sapiens]
Length = 600
Score = 28.5 bits (62), Expect = 5.0
Identities = 13/28 (46%), Positives = 19/28 (67%)
Query: 95 VPVEITISLLKREMDQTMAANAQKNKFL 122
+PV I++ LLKREM Q + A+K + L
Sbjct: 452 IPVGISLGLLKREMAQGLLPEAKKPRLL 479
>gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 2 [Homo sapiens]
Length = 454
Score = 28.1 bits (61), Expect = 6.5
Identities = 15/59 (25%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
Query: 174 DDNRESLEKRIQTY----LQSTKPIIDLYEEMGKV-KKIDASKSVDEVFDEVVQIFDKE 227
+DN E++ K++ Y + ++ LYEE + ++I ++ E F+E ++IF+++
Sbjct: 169 EDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQ 227
>gi|32455250 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 3 [Homo sapiens]
Length = 424
Score = 28.1 bits (61), Expect = 6.5
Identities = 15/59 (25%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
Query: 174 DDNRESLEKRIQTY----LQSTKPIIDLYEEMGKV-KKIDASKSVDEVFDEVVQIFDKE 227
+DN E++ K++ Y + ++ LYEE + ++I ++ E F+E ++IF+++
Sbjct: 139 EDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQ 197
>gi|32455248 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 1 [Homo sapiens]
Length = 724
Score = 28.1 bits (61), Expect = 6.5
Identities = 15/59 (25%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
Query: 174 DDNRESLEKRIQTY----LQSTKPIIDLYEEMGKV-KKIDASKSVDEVFDEVVQIFDKE 227
+DN E++ K++ Y + ++ LYEE + ++I ++ E F+E ++IF+++
Sbjct: 439 EDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQ 497
>gi|13569934 sperm acrosome associated 1 [Homo sapiens]
Length = 294
Score = 28.1 bits (61), Expect = 6.5
Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 28 CSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGE 83
CS L+ + +L G + +GT V+ G H GE +E +N DS+ E
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGE---EETENNDSETAE 60
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 28.1 bits (61), Expect = 6.5
Identities = 30/179 (16%), Positives = 64/179 (35%), Gaps = 40/179 (22%)
Query: 31 RLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDE--------RKNPDSQYG 82
R + P+ + +LG P GK + + Y H+ +++ + N +
Sbjct: 363 RGLMPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGE 422
Query: 83 ELIEKYIKEGKIVPVEITISLLKREMDQT-----------------MAANAQKNKFLIDG 125
E +E+ +E + + + +K M+Q + + +++DG
Sbjct: 423 EEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDG 482
Query: 126 FPR---------------NQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKS 169
FP+ +D+++G D FV D ++E ER + +S
Sbjct: 483 FPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPES 541
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,618,151
Number of Sequences: 37866
Number of extensions: 387094
Number of successful extensions: 1039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 980
Number of HSP's gapped (non-prelim): 47
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.