Guide to the Human Genome
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Search of human proteins with 7706387

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706387 plasma glutamate carboxypeptidase [Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706387 plasma glutamate carboxypeptidase [Homo sapiens]           935   0.0  
gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo ...    51   2e-06
gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens]                 50   4e-06
gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens]                50   4e-06
gi|24308545 folate hydrolase 1B [Homo sapiens]                         50   4e-06
gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1 ...    44   4e-04
gi|189458819 transferrin receptor [Homo sapiens]                       39   0.008
gi|189458817 transferrin receptor [Homo sapiens]                       39   0.008
gi|33589848 transferrin receptor 2 [Homo sapiens]                      39   0.013
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]             32   1.6  
gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]             32   1.6  
gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Hom...    30   6.2  
gi|26190608 synaptojanin 2 [Homo sapiens]                              30   6.2  
gi|124430752 kinesin family member 26B [Homo sapiens]                  30   6.2  

>gi|7706387 plasma glutamate carboxypeptidase [Homo sapiens]
          Length = 472

 Score =  935 bits (2417), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MKFLIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQ 60
           MKFLIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQ
Sbjct: 1   MKFLIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQ 60

Query: 61  NRSYERLALLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLEKVHLEPVRIPHWERGEESA 120
           NRSYERLALLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLEKVHLEPVRIPHWERGEESA
Sbjct: 61  NRSYERLALLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLEKVHLEPVRIPHWERGEESA 120

Query: 121 VMLEPRIHKIAILGLGSSIGTPPEGITAEVLVVTSFDELQRRASEARGKIVVYNQPYINY 180
           VMLEPRIHKIAILGLGSSIGTPPEGITAEVLVVTSFDELQRRASEARGKIVVYNQPYINY
Sbjct: 121 VMLEPRIHKIAILGLGSSIGTPPEGITAEVLVVTSFDELQRRASEARGKIVVYNQPYINY 180

Query: 181 SRTVQYRTQGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVEDAE 240
           SRTVQYRTQGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVEDAE
Sbjct: 181 SRTVQYRTQGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVEDAE 240

Query: 241 MMSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGA 300
           MMSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGA
Sbjct: 241 MMSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGA 300

Query: 301 MDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGAFQYYQLHKVNISNYSLV 360
           MDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGAFQYYQLHKVNISNYSLV
Sbjct: 301 MDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGAFQYYQLHKVNISNYSLV 360

Query: 361 MESDAGTFLPTGLQFTGSEKARAIMEEVMSLLQPLNITQVLSHGEGTDINFWIQAGVPGA 420
           MESDAGTFLPTGLQFTGSEKARAIMEEVMSLLQPLNITQVLSHGEGTDINFWIQAGVPGA
Sbjct: 361 MESDAGTFLPTGLQFTGSEKARAIMEEVMSLLQPLNITQVLSHGEGTDINFWIQAGVPGA 420

Query: 421 SLLDDLYKYFFFHHSHGDTMTVMDPKQMNVAAAVWAVVSYVVADMEEMLPRS 472
           SLLDDLYKYFFFHHSHGDTMTVMDPKQMNVAAAVWAVVSYVVADMEEMLPRS
Sbjct: 421 SLLDDLYKYFFFHHSHGDTMTVMDPKQMNVAAAVWAVVSYVVADMEEMLPRS 472


>gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo
           sapiens]
          Length = 740

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 44/150 (29%), Positives = 65/150 (43%), Gaps = 31/150 (20%)

Query: 225 GVPKIPTACITVEDAEMMSRMASHGIKIVIQLKMGAKT--------YPDTDSF------- 269
           G+P+IP   I   DAE++ R    GI    +   GA          +  +DSF       
Sbjct: 278 GIPRIPVHPIGYNDAEILLRYLG-GIAPPDKSWKGALNVSYSIGPGFTGSDSFRKVRMHV 336

Query: 270 ----------NTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWE---ALSL 316
                     N V  I GS  P++ V++ GH DSW    GA+D   G  +  E   +   
Sbjct: 337 YNINKITRIYNVVGTIRGSVEPDRYVILGGHRDSWVF--GAIDPTSGVAVLQEIARSFGK 394

Query: 317 IKDLGLRPKRTLRLVLWTAEEQGGVGAFQY 346
           +   G RP+RT+    W AEE G +G+ ++
Sbjct: 395 LMSKGWRPRRTIIFASWDAEEFGLLGSTEW 424


>gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens]
          Length = 750

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 266 TDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWE---ALSLIKDLGL 322
           T  +N +  + G+  P++ V++ GH DSW    G +D   GA +  E   +   +K  G 
Sbjct: 353 TRIYNVIGTLRGAVEPDRYVILGGHRDSWVF--GGIDPQSGAAVVHEIVRSFGTLKKEGW 410

Query: 323 RPKRTLRLVLWTAEEQGGVGAFQY 346
           RP+RT+    W AEE G +G+ ++
Sbjct: 411 RPRRTILFASWDAEEFGLLGSTEW 434


>gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens]
          Length = 719

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 266 TDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWE---ALSLIKDLGL 322
           T  +N +  + G+  P++ V++ GH DSW    G +D   GA +  E   +   +K  G 
Sbjct: 353 TRIYNVIGTLRGAVEPDRYVILGGHRDSWVF--GGIDPQSGAAVVHEIVRSFGTLKKEGW 410

Query: 323 RPKRTLRLVLWTAEEQGGVGAFQY 346
           RP+RT+    W AEE G +G+ ++
Sbjct: 411 RPRRTILFASWDAEEFGLLGSTEW 434


>gi|24308545 folate hydrolase 1B [Homo sapiens]
          Length = 442

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 266 TDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWE---ALSLIKDLGL 322
           T  +N +  + G+  P++ V++ GH DSW    G +D   GA +  E   +   +K  G 
Sbjct: 45  TRIYNVIGTLRGAVEPDRYVILGGHRDSWVF--GGIDPQSGAAVVHETVRSFGTLKKEGW 102

Query: 323 RPKRTLRLVLWTAEEQGGVGAFQY 346
           RP+RT+    W AEE G +G+ ++
Sbjct: 103 RPRRTILFASWDAEEFGLLGSTEW 126


>gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1
           [Homo sapiens]
          Length = 740

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 6/84 (7%)

Query: 267 DSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEAL----SLIKDLGL 322
           +S N +  I G+  P++ VL   H DSW    GA+D   G  +  E      +L+K    
Sbjct: 345 NSSNVLGIIRGAVEPDRYVLYGNHRDSW--VHGAVDPSSGTAVLLELSRVLGTLLKKGTW 402

Query: 323 RPKRTLRLVLWTAEEQGGVGAFQY 346
           RP+R++    W AEE G +G+ ++
Sbjct: 403 RPRRSIVFASWGAEEFGLIGSTEF 426


>gi|189458819 transferrin receptor [Homo sapiens]
          Length = 760

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 270 NTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDL----GLRPK 325
           N    I G   P+  V+V    D+W  G GA   G G  +  +   +  D+    G +P 
Sbjct: 388 NIFGVIKGFVEPDHYVVVGAQRDAW--GPGAAKSGVGTALLLKLAQMFSDMVLKDGFQPS 445

Query: 326 RTLRLVLWTAEEQGGVGAFQYYQ 348
           R++    W+A + G VGA ++ +
Sbjct: 446 RSIIFASWSAGDFGSVGATEWLE 468


>gi|189458817 transferrin receptor [Homo sapiens]
          Length = 760

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 270 NTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDL----GLRPK 325
           N    I G   P+  V+V    D+W  G GA   G G  +  +   +  D+    G +P 
Sbjct: 388 NIFGVIKGFVEPDHYVVVGAQRDAW--GPGAAKSGVGTALLLKLAQMFSDMVLKDGFQPS 445

Query: 326 RTLRLVLWTAEEQGGVGAFQYYQ 348
           R++    W+A + G VGA ++ +
Sbjct: 446 RSIIFASWSAGDFGSVGATEWLE 468


>gi|33589848 transferrin receptor 2 [Homo sapiens]
          Length = 801

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 12/129 (9%)

Query: 275 ITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDL---GLRPKRTLRLV 331
           I G   P+  V++    D+W  G GA     G  I  E +     +   G RP+R+L  +
Sbjct: 417 IEGRSEPDHYVVIGAQRDAW--GPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFI 474

Query: 332 LWTAEEQGGVGAFQYYQLHKVNISNYSLVMESDAGTFLPTGLQFTGSEKARAIMEEVMSL 391
            W   + G VG+ ++       +  Y  V+   A  ++       G +K  A    +++ 
Sbjct: 475 SWDGGDFGSVGSTEW-------LEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLLTS 527

Query: 392 LQPLNITQV 400
           L    + QV
Sbjct: 528 LIESVLKQV 536


>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
          Length = 1069

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 18/83 (21%), Positives = 39/83 (46%)

Query: 4    LIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQNRS 63
            ++ A  GG  L ++C     C N +     E + E+I        A+I+L    + Q++ 
Sbjct: 951  VVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSKY 1010

Query: 64   YERLALLVDTVGPRLSGSKNLEK 86
            ++ + ++    G  L+G++  E+
Sbjct: 1011 WKSVRMVAVPRGCALAGAQLQEE 1033


>gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]
          Length = 1066

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 18/83 (21%), Positives = 39/83 (46%)

Query: 4    LIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQNRS 63
            ++ A  GG  L ++C     C N +     E + E+I        A+I+L    + Q++ 
Sbjct: 948  VVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSKY 1007

Query: 64   YERLALLVDTVGPRLSGSKNLEK 86
            ++ + ++    G  L+G++  E+
Sbjct: 1008 WKSVRMVAVPRGCALAGAQLQEE 1030


>gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Homo
           sapiens]
          Length = 795

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 26/117 (22%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 232 ACITVEDAEMMSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYPEQVVLVSGHL 291
           AC ++E      R+ S  ++ V +LK            N V  + G   P++ ++V  H 
Sbjct: 402 ACSSLELPNNEIRVVSMQVQTVTKLKTVT---------NVVGFVMGLTSPDRYIIVGSHH 452

Query: 292 DSWDVGQGAMDDGGGAFISWEALSLIKDL--GLRPKRTLRLVLWTAEEQGGVGAFQY 346
            +     G       A I+    +L+  +  G RP RT+    W     G +G++++
Sbjct: 453 HTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEW 509


>gi|26190608 synaptojanin 2 [Homo sapiens]
          Length = 1496

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 6/107 (5%)

Query: 192 VEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVED--AEMMSRMASHG 249
           V+   VGA   + + V+SF      T +   Q   P +       ED   E+M  + S+G
Sbjct: 866 VQEVDVGARERVFQEVSSFQGPLDATVVVNLQS--PTLEEKNEFPEDLRTELMQTLGSYG 923

Query: 250 IKIVIQLKMGAK--TYPDTDSFNTVAEITGSKYPEQVVLVSGHLDSW 294
             +++++  G    T+ D+ S  +V ++ G K   + V +      W
Sbjct: 924 TIVLVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDW 970


>gi|124430752 kinesin family member 26B [Homo sapiens]
          Length = 2108

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 4/52 (7%)

Query: 296  VGQGAMDDGGGAFISW--EALSLIKDLGLRPKRTLRLVLWTAEE--QGGVGA 343
            VGQG+    GG    W  ++LS  +  GL  K  LR V     E  QGG GA
Sbjct: 1767 VGQGSSSPPGGKHTPWSTQSLSRNRSSGLASKLPLRAVSGRISELLQGGAGA 1818


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,936,241
Number of Sequences: 37866
Number of extensions: 713486
Number of successful extensions: 1402
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1389
Number of HSP's gapped (non-prelim): 16
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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