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Search of human proteins with 7706363
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706363 map kinase phosphatase-like protein MK-STYX [Homo
sapiens]
(313 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706363 map kinase phosphatase-like protein MK-STYX [Homo sap... 647 0.0
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 70 2e-12
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 70 3e-12
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 69 5e-12
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 69 7e-12
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 65 8e-11
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 64 2e-10
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 62 9e-10
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 62 9e-10
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 62 9e-10
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 60 2e-09
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 59 6e-09
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 56 4e-08
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 56 4e-08
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 55 8e-08
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 55 8e-08
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 55 1e-07
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 54 2e-07
gi|37674210 slingshot 2 [Homo sapiens] 54 2e-07
gi|239582767 slingshot homolog 3 [Homo sapiens] 53 3e-07
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 52 7e-07
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 52 7e-07
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 52 7e-07
gi|51491914 dual specificity phosphatase and pro isomerase domai... 51 2e-06
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 51 2e-06
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 49 4e-06
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 49 8e-06
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 48 1e-05
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 48 1e-05
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 47 3e-05
>gi|7706363 map kinase phosphatase-like protein MK-STYX [Homo
sapiens]
Length = 313
Score = 647 bits (1670), Expect = 0.0
Identities = 313/313 (100%), Positives = 313/313 (100%)
Query: 1 MPGLLLCEPTELYNILNQATKLSRLTDPNYLCLLDVRSKWEYDESHVITALRVKKKNNEY 60
MPGLLLCEPTELYNILNQATKLSRLTDPNYLCLLDVRSKWEYDESHVITALRVKKKNNEY
Sbjct: 1 MPGLLLCEPTELYNILNQATKLSRLTDPNYLCLLDVRSKWEYDESHVITALRVKKKNNEY 60
Query: 61 LLPESVDLECVKYCVVYDNNSSTLEILLKDDDDDSDSDGDGKDLVPQAAIEYGRILTRLT 120
LLPESVDLECVKYCVVYDNNSSTLEILLKDDDDDSDSDGDGKDLVPQAAIEYGRILTRLT
Sbjct: 61 LLPESVDLECVKYCVVYDNNSSTLEILLKDDDDDSDSDGDGKDLVPQAAIEYGRILTRLT 120
Query: 121 HHPVYILKGGYERFSGTYHFLRTQKIIWMPQELDAFQPYPIEIVPGKVFVGNFSQACDPK 180
HHPVYILKGGYERFSGTYHFLRTQKIIWMPQELDAFQPYPIEIVPGKVFVGNFSQACDPK
Sbjct: 121 HHPVYILKGGYERFSGTYHFLRTQKIIWMPQELDAFQPYPIEIVPGKVFVGNFSQACDPK 180
Query: 181 IQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGS 240
IQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGS
Sbjct: 181 IQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGS 240
Query: 241 VILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWEKTI 300
VILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWEKTI
Sbjct: 241 VILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWEKTI 300
Query: 301 LGDSITNIMDPLY 313
LGDSITNIMDPLY
Sbjct: 301 LGDSITNIMDPLY 313
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 70.1 bits (170), Expect = 2e-12
Identities = 72/292 (24%), Positives = 128/292 (43%), Gaps = 45/292 (15%)
Query: 33 LLDVRSKWEYDESHVITALRV--------KKKNNEYLLPE--------SVDLECVKYCVV 76
L+D R EY+ SH++ A+ + + + ++ L+ E VD++C + VV
Sbjct: 28 LIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVV 87
Query: 77 YDNNSSTLEILLKDDDDDSDSDGDGKDLVPQAAIEYGRILTRLTHHPVYILKGGYERFSG 136
YD +S + L D + G++ + + V++L GG+ FS
Sbjct: 88 YDQSSQDVASLSSDCF---------------LTVLLGKL--EKSFNSVHLLAGGFAEFSR 130
Query: 137 TYHFLRTQKIIWMPQELDAFQPY-------PIEIVPGKVFVGNFSQACDPKIQKDLKIKA 189
+ L K +P + QP P I+P +++G + ++ + I
Sbjct: 131 CFPGLCEGKSTLVPTCIS--QPCLPVANIGPTRILPN-LYLGCQRDVLNKELMQQNGIGY 187
Query: 190 HVNVSMDTG-PFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQ 248
+N S P F ++ L + + DS +ILP+L FIE +L+
Sbjct: 188 VLNASNTCPKPDFIPESH-FLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLA 246
Query: 249 GISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWEKTI 300
GISRS IAY+M + +L ++ +VK+ + + PN + QLL++EK I
Sbjct: 247 GISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKI 298
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 69.7 bits (169), Expect = 3e-12
Identities = 60/229 (26%), Positives = 100/229 (43%), Gaps = 22/229 (9%)
Query: 93 DDSDSDGDGKDLVPQAAIEYGRILTRLTHHPVYILKGGYERFSGTYHFLRTQKIIWMPQE 152
D+ + DG A+ G + V+ LKGGYE FS + L +++ M
Sbjct: 87 DERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLS 146
Query: 153 LDAF--------------------QPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVN 192
L Q P+EI+P +++G+ A + L I A +N
Sbjct: 147 LPLSTSVPDSAESGCSSCSTPLYDQGGPVEILP-FLYLGSAYHASRKDMLDALGITALIN 205
Query: 193 VSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISR 252
VS + F G + I +ED+ +A I + FI+ + G + + GISR
Sbjct: 206 VSANCPNHFEGHY-QYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISR 264
Query: 253 SCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWEKTIL 301
S +AYLM +N L ++ +VK+ ++ + PN + QLL++E +L
Sbjct: 265 SATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVL 313
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 68.9 bits (167), Expect = 5e-12
Identities = 67/250 (26%), Positives = 107/250 (42%), Gaps = 37/250 (14%)
Query: 75 VVYDNNSSTLEILLKDDDDDSDSDGDGKDLVPQAAIEYGRILTRLTHHPVYILKGGYERF 134
+VYD S E L +D LV QA + + +LKGGYERF
Sbjct: 106 IVYDERSPRAESLREDST---------VSLVVQA------LRRNAERTDICLLKGGYERF 150
Query: 135 SGTYHFL--RTQKIIWMPQEL--DAFQPY----------------PIEIVPGKVFVGNFS 174
S Y +T+ + +P + A +P P+EI+P +++G+
Sbjct: 151 SSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPF-LYLGSAY 209
Query: 175 QACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEI 234
A + L I A +NVS D F G I +ED+ +A I + +I+
Sbjct: 210 HAARRDMLDALGITALLNVSSDCPNHFEGHYQYKC-IPVEDNHKADISSWFMEAIEYIDA 268
Query: 235 HHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLL 294
+L+ GISRS +AYLM L+ ++ +VK+ ++ + PN + QLL
Sbjct: 269 VKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLL 328
Query: 295 EWEKTILGDS 304
++E +L S
Sbjct: 329 QFESQVLATS 338
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 68.6 bits (166), Expect = 7e-12
Identities = 61/202 (30%), Positives = 94/202 (46%), Gaps = 29/202 (14%)
Query: 124 VYILKGGYERFSGTYHF-------LRTQKI---------IWMPQELDAFQPY-----PIE 162
VY LKGGYE F Y + +KI P +++P P+E
Sbjct: 122 VYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVE 181
Query: 163 IVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLH---IRIEDSPEA 219
I+P +++G+ A + +L I A +NVS T A LH I +EDS A
Sbjct: 182 ILPF-LYLGSAYHASKCEFLANLHITALLNVSRRTSEACATH----LHYKWIPVEDSHTA 236
Query: 220 QILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKC 279
I + FI+ G +L+ GISRS +AYLM + + L+ ++ Y+K+
Sbjct: 237 DISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQR 296
Query: 280 KNNMCPNRGLVSQLLEWEKTIL 301
++ + PN G + QLL++E IL
Sbjct: 297 RSMVSPNFGFMGQLLQYESEIL 318
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 65.1 bits (157), Expect = 8e-11
Identities = 56/197 (28%), Positives = 92/197 (46%), Gaps = 14/197 (7%)
Query: 117 TRLTHHPVYILKGGYERFSGTYHFLRTQKII-WMPQELDAF-----------QPYPIEIV 164
TR VY L+GG++ F G L ++ +P D Q P+EI+
Sbjct: 118 TRAGPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEIL 177
Query: 165 PGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPF 224
P +F+G+ S + D + + I A +NVS F G + I +ED+ +I +
Sbjct: 178 P-YLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEG-LFRYKSIPVEDNQMVEISAW 235
Query: 225 LRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMC 284
+ FI+ + G +L+ GISRS +AYLM S L ++ +VK+ + +
Sbjct: 236 FQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVIS 295
Query: 285 PNRGLVSQLLEWEKTIL 301
PN + QLL++E +L
Sbjct: 296 PNFSFMGQLLQFETQVL 312
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 63.9 bits (154), Expect = 2e-10
Identities = 54/197 (27%), Positives = 90/197 (45%), Gaps = 22/197 (11%)
Query: 128 KGGYERFSGTYHFL--RTQKIIWMPQEL--DAFQPY----------------PIEIVPGK 167
+GGYERFS Y +T+ + +P + A +P P+EI+P
Sbjct: 53 QGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPF- 111
Query: 168 VFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRH 227
+++G+ A + L I A +NVS D F G I +ED+ +A I +
Sbjct: 112 LYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKC-IPVEDNHKADISSWFME 170
Query: 228 MCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNR 287
+I+ +L+ GISRS +AYLM L+ ++ +VK+ ++ + PN
Sbjct: 171 AIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNF 230
Query: 288 GLVSQLLEWEKTILGDS 304
+ QLL++E +L S
Sbjct: 231 SFMGQLLQFESQVLATS 247
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 61.6 bits (148), Expect = 9e-10
Identities = 48/159 (30%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 162 EIVPGKVFVGNFSQACD---PKIQKD-----LKIKAHVNVSMDTGPFFAGDADKLLHIRI 213
EI+PG +F+G +S A P +QK + I+ ++ + F + L + I
Sbjct: 31 EILPG-LFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNF--QQLFRYLVLDI 87
Query: 214 EDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSW 273
D+P I+ F FI+ +G +L+ GISRS A +IAY+M + + ++
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 274 AYVKKCKNNMCPNRGLVSQLLEWEKTILGDSITNIMDPL 312
AYV++ + + PN G V QL E+E L +M PL
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPL 186
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 61.6 bits (148), Expect = 9e-10
Identities = 48/159 (30%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 162 EIVPGKVFVGNFSQACD---PKIQKD-----LKIKAHVNVSMDTGPFFAGDADKLLHIRI 213
EI+PG +F+G +S A P +QK + I+ ++ + F + L + I
Sbjct: 31 EILPG-LFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNF--QQLFRYLVLDI 87
Query: 214 EDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSW 273
D+P I+ F FI+ +G +L+ GISRS A +IAY+M + + ++
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 274 AYVKKCKNNMCPNRGLVSQLLEWEKTILGDSITNIMDPL 312
AYV++ + + PN G V QL E+E L +M PL
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPL 186
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 61.6 bits (148), Expect = 9e-10
Identities = 48/159 (30%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 162 EIVPGKVFVGNFSQACD---PKIQKD-----LKIKAHVNVSMDTGPFFAGDADKLLHIRI 213
EI+PG +F+G +S A P +QK + I+ ++ + F + L + I
Sbjct: 31 EILPG-LFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNF--QQLFRYLVLDI 87
Query: 214 EDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSW 273
D+P I+ F FI+ +G +L+ GISRS A +IAY+M + + ++
Sbjct: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
Query: 274 AYVKKCKNNMCPNRGLVSQLLEWEKTILGDSITNIMDPL 312
AYV++ + + PN G V QL E+E L +M PL
Sbjct: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPL 186
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 60.5 bits (145), Expect = 2e-09
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Query: 161 IEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQ 220
+ ++ + +G+ A D K K+ +NV+ F D I I D PE
Sbjct: 66 VGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFT-YKSISILDLPETN 124
Query: 221 ILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCK 280
IL + FIE V+L+ G+SR+ A +I +LM+S + + +++ VK +
Sbjct: 125 ILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNAR 184
Query: 281 NNMCPNRGLVSQLLEWEK 298
++CPN G + QL +++
Sbjct: 185 PSICPNSGFMEQLRTYQE 202
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 58.9 bits (141), Expect = 6e-09
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 3/146 (2%)
Query: 168 VFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIE--DSPEAQILPFL 225
+F+GN A D + L I +NV+ P + + + R+ DS + + +
Sbjct: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHL-PLYHYEKGLFNYKRLPATDSNKQNLRQYF 387
Query: 226 RHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCP 285
FIE H G +LI G+SRS +IAYLM T+ ++ +VK + + P
Sbjct: 388 EEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISP 447
Query: 286 NRGLVSQLLEWEKTILGDSITNIMDP 311
N + QLLE+E+ + I+ P
Sbjct: 448 NLNFMGQLLEFEEDLNNGVTPRILTP 473
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 56.2 bits (134), Expect = 4e-08
Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 2/143 (1%)
Query: 159 YPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDAD-KLLHIRIEDSP 217
+P+EI+P +++G + + + ++ IK +NV+ + F + K I I D
Sbjct: 206 FPVEILPF-LYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHW 264
Query: 218 EAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVK 277
+ F FI+ +L+ GISRS +AYLM ++ ++ VK
Sbjct: 265 SQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVK 324
Query: 278 KCKNNMCPNRGLVSQLLEWEKTI 300
K+N+ PN + QLL++E+T+
Sbjct: 325 MKKSNISPNFNFMGQLLDFERTL 347
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 56.2 bits (134), Expect = 4e-08
Identities = 37/143 (25%), Positives = 71/143 (49%), Gaps = 2/143 (1%)
Query: 159 YPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDAD-KLLHIRIEDSP 217
+P++I+P +++G+ + + + L I+ +NV+ + FF + D I I D
Sbjct: 203 FPVQILPN-LYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHW 261
Query: 218 EAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVK 277
+ F FI+ +L+ G+SRS +AYLM +L ++ VK
Sbjct: 262 SQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVK 321
Query: 278 KCKNNMCPNRGLVSQLLEWEKTI 300
+ K+N+ PN + QLL++E+++
Sbjct: 322 RKKSNISPNFNFMGQLLDFERSL 344
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 55.1 bits (131), Expect = 8e-08
Identities = 30/97 (30%), Positives = 47/97 (48%)
Query: 215 DSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWA 274
DS + + + FIE H G +LI G+SRS +IAYLM T+ ++
Sbjct: 35 DSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYK 94
Query: 275 YVKKCKNNMCPNRGLVSQLLEWEKTILGDSITNIMDP 311
+VK + + PN + QLLE+E+ + I+ P
Sbjct: 95 FVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 131
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 55.1 bits (131), Expect = 8e-08
Identities = 30/97 (30%), Positives = 47/97 (48%)
Query: 215 DSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWA 274
DS + + + FIE H G +LI G+SRS +IAYLM T+ ++
Sbjct: 35 DSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYK 94
Query: 275 YVKKCKNNMCPNRGLVSQLLEWEKTILGDSITNIMDP 311
+VK + + PN + QLLE+E+ + I+ P
Sbjct: 95 FVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 131
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 54.7 bits (130), Expect = 1e-07
Identities = 43/148 (29%), Positives = 65/148 (43%), Gaps = 3/148 (2%)
Query: 158 PYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVS-MDTGPFFAGDADKLLHIRIEDS 216
P P+ V +F+G+ A + + VNVS GP G A+ L + + D
Sbjct: 16 PPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAE--LRVPVFDD 73
Query: 217 PEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYV 276
P +L L C +E G L++ G SRS A AYLM +L +++ V
Sbjct: 74 PAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMV 133
Query: 277 KKCKNNMCPNRGLVSQLLEWEKTILGDS 304
K + PN G SQL ++E+ + S
Sbjct: 134 KSARPVAEPNPGFWSQLQKYEEALQAQS 161
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 53.9 bits (128), Expect = 2e-07
Identities = 38/143 (26%), Positives = 68/143 (47%), Gaps = 2/143 (1%)
Query: 159 YPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDT-GPFFAGDADKLLHIRIEDSP 217
+P++I+P +++G + + + IK +NV+ + F G I I D
Sbjct: 244 FPVQILP-YLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHW 302
Query: 218 EAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVK 277
+ F FI+ +L+ GISRS +AYLM +L ++ +VK
Sbjct: 303 SQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVK 362
Query: 278 KCKNNMCPNRGLVSQLLEWEKTI 300
+ K+N+ PN + QLL++E+T+
Sbjct: 363 RKKSNISPNFNFMGQLLDFERTL 385
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 1/134 (0%)
Query: 168 VFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRH 227
VF+G+ A + + ++ ++ +NV+ + FF G + +IR+ D +L +
Sbjct: 315 VFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPG-VFEYHNIRVYDEEATDLLAYWND 373
Query: 228 MCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNR 287
FI GS L+ G+SRS + +IAY M L R++ YVK+ + PN
Sbjct: 374 TYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNP 433
Query: 288 GLVSQLLEWEKTIL 301
+ QL E++ +L
Sbjct: 434 SFMRQLEEYQGILL 447
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 53.1 bits (126), Expect = 3e-07
Identities = 27/84 (32%), Positives = 47/84 (55%)
Query: 210 HIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTL 269
++R+ D AQ+LP + FIE G+ +L+ G+SRS A ++AY M E +L
Sbjct: 377 NVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSL 436
Query: 270 QRSWAYVKKCKNNMCPNRGLVSQL 293
+++ +V++ + PN G + QL
Sbjct: 437 EQALRHVQELRPIARPNPGFLRQL 460
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 52.0 bits (123), Expect = 7e-07
Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 191 VNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGI 250
+NV+ + FF G +IR+ D +L HFI S L+ G+
Sbjct: 339 LNVTREIDNFFPG-LFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV 397
Query: 251 SRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWE 297
SRS + +IAY M L++++ YVK+ ++ PN G + QL E+E
Sbjct: 398 SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE 444
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 52.0 bits (123), Expect = 7e-07
Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 191 VNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGI 250
+NV+ + FF G +IR+ D +L HFI S L+ G+
Sbjct: 350 LNVTREIDNFFPG-LFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV 408
Query: 251 SRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWE 297
SRS + +IAY M L++++ YVK+ ++ PN G + QL E+E
Sbjct: 409 SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE 455
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 52.0 bits (123), Expect = 7e-07
Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 191 VNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGI 250
+NV+ + FF G +IR+ D +L HFI S L+ G+
Sbjct: 339 LNVTREIDNFFPG-LFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGV 397
Query: 251 SRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWE 297
SRS + +IAY M L++++ YVK+ ++ PN G + QL E+E
Sbjct: 398 SRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE 444
>gi|51491914 dual specificity phosphatase and pro isomerase domain
containing 1 [Homo sapiens]
Length = 220
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 16/146 (10%)
Query: 167 KVFVGNFSQACDP-KIQK----DLKIKAHVNVSMDTGPFFAGDADKLLH-IRIEDSPEAQ 220
K+++G+ + A D ++QK + AH ++DTGP + D D H + +D P
Sbjct: 61 KLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFD 120
Query: 221 ILPFLRHMCHFIE---IHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVK 277
+ F FI+ H S IL+ G SRS ++AYLM + TL + ++
Sbjct: 121 LSVFFYPAAAFIDRALSDDH--SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDA---IQ 175
Query: 278 KCKNNMC--PNRGLVSQLLEWEKTIL 301
+ N C PNRG + QL E +K ++
Sbjct: 176 QVAKNRCVLPNRGFLKQLRELDKQLV 201
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 50.8 bits (120), Expect = 2e-06
Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 9/141 (6%)
Query: 168 VFVGNFSQACDPKIQKDLKIKAHVNVSMDTG-----PFFAGDADKLLHIRIEDSPEAQIL 222
VF+ S A + K L I +N + TG F+ G + L + ++D PE I
Sbjct: 141 VFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQYLGVEVDDFPEVDIS 200
Query: 223 PFLRHMCHFIE--IHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCK 280
R F++ + + G V L+ S GISRS ++AYLM + + + V+K K
Sbjct: 201 QHFRKASEFLDEALLTYRGKV-LVSSEMGISRSAVLVVAYLMIFHNMAILEALMTVRK-K 258
Query: 281 NNMCPNRGLVSQLLEWEKTIL 301
+ PN G + QL E + ++
Sbjct: 259 RAIYPNEGFLKQLRELNEKLM 279
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 49.3 bits (116), Expect = 4e-06
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 3/137 (2%)
Query: 162 EIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQI 221
+I+PG +++GNF A D + K+ ++V P G K L I DSP +
Sbjct: 7 KILPG-LYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGV--KYLCIPAADSPSQNL 63
Query: 222 LPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKN 281
+ FI G L+ G+SRS +IAY+M + + + V+ ++
Sbjct: 64 TRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRS 123
Query: 282 NMCPNRGLVSQLLEWEK 298
PN G QL E+EK
Sbjct: 124 CANPNVGFQRQLQEFEK 140
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 48.5 bits (114), Expect = 8e-06
Identities = 32/142 (22%), Positives = 65/142 (45%), Gaps = 1/142 (0%)
Query: 168 VFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRH 227
+++ N A + + +I +NVS++ D + + + + DSP +++ F
Sbjct: 27 LYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDI-QYMQVPVADSPNSRLCDFFDP 85
Query: 228 MCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNR 287
+ I L+ G+SRS A +AYLM + +L + + K C+ + PN
Sbjct: 86 IADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNS 145
Query: 288 GLVSQLLEWEKTILGDSITNIM 309
G QL+ +E + G + +++
Sbjct: 146 GFWEQLIHYEFQLFGKNTVHMV 167
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 48.1 bits (113), Expect = 1e-05
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Query: 124 VYILKGGYERFSGTYHFLRTQK-IIWMPQELDA-FQPYP----IEIVPGKVFVGNFSQAC 177
V IL GG+ FS + L K +P L P P I+P +++G+
Sbjct: 119 VAILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILP-HLYLGSQKDVL 177
Query: 178 DPKIQKDLKIKAHVNVSMDTG-PFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHH 236
+ + I +N S P F ++ + + + I D+ ++LP+L FI+
Sbjct: 178 NKDLMTQNGISYVLNASNSCPKPDFICES-RFMRVPINDNYCEKLLPWLDKSIEFIDKAK 236
Query: 237 HLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEW 296
+++ GISRS IAY+M + + ++ +VK + ++ PN + QLLE+
Sbjct: 237 LSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEY 296
Query: 297 EKTI 300
E+++
Sbjct: 297 ERSL 300
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 1/150 (0%)
Query: 164 VPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILP 223
+ +F+G S A + + + I VN +++ P F + + + + D P A I
Sbjct: 30 ITSSLFLGRGSVASNRHLLQARGITCIVNATIEI-PNFNWPQFEYVKVPLADMPHAPIGL 88
Query: 224 FLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNM 283
+ + I L+ G+SRS IAYLM + L ++ +VK + +
Sbjct: 89 YFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVI 148
Query: 284 CPNRGLVSQLLEWEKTILGDSITNIMDPLY 313
PN G QL+++E+ + G S ++ Y
Sbjct: 149 RPNVGFWRQLIDYERQLFGKSTVKMVQTPY 178
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 46.6 bits (109), Expect = 3e-05
Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 6/117 (5%)
Query: 189 AHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHL---GSVILIF 245
AH + GP F G + L + D P+ I + FI H L G+ +L+
Sbjct: 71 AHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFI--HRALNTPGAKVLVH 128
Query: 246 STQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWEKTILG 302
G+SRS ++AYLM +L+++ V++ + PNRG + QL ++ + G
Sbjct: 129 CVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQ-HRWVFPNRGFLHQLCRLDQQLRG 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,615,783
Number of Sequences: 37866
Number of extensions: 565013
Number of successful extensions: 1616
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1555
Number of HSP's gapped (non-prelim): 66
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.