Search of human proteins with 7705987

Search of human proteins with 7705987

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705987 glycolipid transfer protein [Homo sapiens]
         (209 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705987 glycolipid transfer protein [Homo sapiens]                 424   e-119
gi|7705684 pleckstrin homology domain containing, family A (phos...   104   6e-23
gi|14249174 pleckstrin homology domain containing, family A (pho...    79   4e-15
gi|71274150 glycolipid transfer protein domain containing 1 [Hom...    42   4e-04
gi|62526120 glycolipid transfer protein domain containing 2 [Hom...    37   0.009
gi|34577059 adipose differentiation-related protein [Homo sapiens]     29   2.5  
gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3 c...    29   2.5  
gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3 c...    29   2.5  
gi|154689780 son of sevenless homolog 2 [Homo sapiens]                 28   5.6  
gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [...    28   5.6  
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]        28   5.6  
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...    28   7.3  
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...    28   7.3  
gi|4557841 recombination activating gene 1 [Homo sapiens]              27   9.5  
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]              27   9.5  
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]                27   9.5  
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]              27   9.5  
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]              27   9.5  
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]              27   9.5  

>gi|7705987 glycolipid transfer protein [Homo sapiens]
          Length = 209

 Score =  424 bits (1090), Expect = e-119
 Identities = 209/209 (100%), Positives = 209/209 (100%)

Query: 1   MALLAEHLLKPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVY 60
           MALLAEHLLKPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVY
Sbjct: 1   MALLAEHLLKPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVY 60

Query: 61  DTNPAKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENH 120
           DTNPAKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENH
Sbjct: 61  DTNPAKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENH 120

Query: 121 PNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKI 180
           PNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKI
Sbjct: 121 PNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKI 180

Query: 181 RLFLVNYTATIDVIYEMYTQMNAELNYKV 209
           RLFLVNYTATIDVIYEMYTQMNAELNYKV
Sbjct: 181 RLFLVNYTATIDVIYEMYTQMNAELNYKV 209


>gi|7705684 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 9 [Homo
           sapiens]
          Length = 391

 Score =  104 bits (259), Expect = 6e-23
 Identities = 61/152 (40%), Positives = 86/152 (56%), Gaps = 7/152 (4%)

Query: 15  DKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAKFRTLQNIL 74
           D  I T  FL +   + P  D LG  VF P+K D+  NI K+   Y TN  +F TLQ I+
Sbjct: 211 DSGIPTEAFLASCCAVVPVLDKLGPTVFAPVKMDLVENIKKVNQKYITNKEEFTTLQKIV 270

Query: 75  EVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEM 134
             E E   A+  +  AT AL+WLKRGL+F++ FL  + +GE+D      I+     AY  
Sbjct: 271 LHEVEADVAQ-VRNSATEALLWLKRGLKFLKGFLTEVKNGEKD------IQTALNNAYGK 323

Query: 135 ALKKYHGWIVQKIFQAALYAAPYKSDFLKALS 166
            L+++HGW+V+ +F  AL A P   DF+ AL+
Sbjct: 324 TLRQHHGWVVRGVFALALRATPSYEDFVAALT 355


>gi|14249174 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 8 [Homo
           sapiens]
          Length = 440

 Score = 78.6 bits (192), Expect = 4e-15
 Identities = 45/103 (43%), Positives = 61/103 (59%), Gaps = 1/103 (0%)

Query: 15  DKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAKFRTLQNIL 74
           D  I T  FL +   + P  D LG  VF P+K D+ GNI K+   Y TN  +F TLQ I+
Sbjct: 327 DSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIV 386

Query: 75  EVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERD 117
             E E   A+  +  AT AL+WLKRGL+F++ FL  + +GE+D
Sbjct: 387 LHEVEADVAQ-VRNSATEALLWLKRGLKFLKGFLTEVKNGEKD 428


>gi|71274150 glycolipid transfer protein domain containing 1 [Homo
           sapiens]
          Length = 214

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 37/164 (22%), Positives = 75/164 (45%), Gaps = 13/164 (7%)

Query: 12  LPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAK-FRTL 70
           L   +++   P++ +   L  F + LG+ +F+ I  D+   +  ++ +     ++ +R+L
Sbjct: 21  LDEKEEVLLDPYIASWKGLVRFLNSLGT-IFSFISKDVVSKLRIMERLRGGPQSEHYRSL 79

Query: 71  QNIL--EVEKEMYGAE----WPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLI 124
           Q ++  E+   +   E     P+ G    L  L R L ++Q+FL+ +     D     L 
Sbjct: 80  QAMVAHELSNRLVDLERRSHHPESGCRTVLR-LHRALHWLQLFLEGLRTSPEDARTSAL- 137

Query: 125 RVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKG 168
                 +Y  +L  YH W+V++    A    P +  FL+A++ G
Sbjct: 138 ---CADSYNASLAAYHPWVVRRAVTVAFCTLPTREVFLEAMNVG 178


>gi|62526120 glycolipid transfer protein domain containing 2 [Homo
           sapiens]
          Length = 291

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 47/202 (23%), Positives = 79/202 (39%), Gaps = 19/202 (9%)

Query: 12  LPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKA-VYDTNPAKFRTL 70
           L  +  +   P+L     L  F   LGS VF     +    +T ++A V+  +   + +L
Sbjct: 93  LKPEGDVGLSPYLAGWRALVEFLTPLGS-VFAFATREAFTKVTDLEARVHGPDAEHYWSL 151

Query: 71  QNILEVEKEMYGAEWP--------KVGATLALMWLKRGLRFIQVFLQSICDGERDENHPN 122
             +   E+     E P        +   +  L+ L R LR+ Q+ L  +  G        
Sbjct: 152 AAMAAWERRAGLLEQPGAAPRDPTRSSGSRTLLLLHRALRWSQLCLHRVATGALGGPEAG 211

Query: 123 LIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKIRL 182
              V  + AY  AL  +H W+V++  + A  A P +   L+    G   TE E     R 
Sbjct: 212 ---VQCSDAYRAALGPHHPWLVRQTARLAFLAFPGRRRLLELACPG--ATEAEA----RA 262

Query: 183 FLVNYTATIDVIYEMYTQMNAE 204
            L+    T++ +Y     + AE
Sbjct: 263 ALLRAAGTLEDVYNRTQSLLAE 284


>gi|34577059 adipose differentiation-related protein [Homo sapiens]
          Length = 437

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 2/71 (2%)

Query: 138 KYHGWIVQKIFQAALYAAPYK--SDFLKALSKGQNVTEEECLEKIRLFLVNYTATIDVIY 195
           K+ G +   I+     AA +K  SD L   SKGQ    +E L+ +  +LVN T    ++ 
Sbjct: 344 KHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVG 403

Query: 196 EMYTQMNAELN 206
             Y Q+    N
Sbjct: 404 PFYPQLTESQN 414


>gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3
           component n-recognin 5 isoform 2 [Homo sapiens]
          Length = 2277

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 30  LPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAKFRTLQNILEVEKEMYGAEWPKVG 89
           LPP    LG  V + I    +  I K  AV      K   +Q+IL  + E       +  
Sbjct: 334 LPPI-SSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACR----QYL 388

Query: 90  ATLALMWLKRGLRFIQVFLQSICDGERDENH 120
             L   +L++ L+ +Q F+   CDG R+  H
Sbjct: 389 MNLEQRFLEQNLQMLQTFISHRCDGNRNILH 419


>gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3
           component n-recognin 5 isoform 1 [Homo sapiens]
          Length = 2796

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 30  LPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAKFRTLQNILEVEKEMYGAEWPKVG 89
           LPP    LG  V + I    +  I K  AV      K   +Q+IL  + E       +  
Sbjct: 837 LPPI-SSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACR----QYL 891

Query: 90  ATLALMWLKRGLRFIQVFLQSICDGERDENH 120
             L   +L++ L+ +Q F+   CDG R+  H
Sbjct: 892 MNLEQRFLEQNLQMLQTFISHRCDGNRNILH 922


>gi|154689780 son of sevenless homolog 2 [Homo sapiens]
          Length = 1332

 Score = 28.1 bits (61), Expect = 5.6
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 20/96 (20%)

Query: 104 IQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLK 163
           + +  QSI DG ++     L R+       M +  YH W   ++ +            LK
Sbjct: 318 VALHFQSIADGFKEAVRYVLPRL-------MLVPVYHCWHYFELLKQ-----------LK 359

Query: 164 ALSKGQNVTEEECLEKIRLFLVNYTATIDVIYEMYT 199
           A S+ Q   + ECL +    L+N   ++D IY+ Y+
Sbjct: 360 ACSEEQE--DRECLNQAITALMNLQGSMDRIYKQYS 393


>gi|15147337 ubiquitin protein ligase E3 component n-recognin 5
           [Homo sapiens]
          Length = 2799

 Score = 28.1 bits (61), Expect = 5.6
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 4/91 (4%)

Query: 30  LPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPAKFRTLQNILEVEKEMYGAEWPKVG 89
           LPP    LG  V + I    +  I K  AV      K   +Q+IL  + E        + 
Sbjct: 838 LPPI-SSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLE 896

Query: 90  ATLALMWLKRGLRFIQVFLQSICDGERDENH 120
             + L   ++ L+ +Q F+   CDG R+  H
Sbjct: 897 QAVVL---EQNLQMLQTFISHRCDGNRNILH 924


>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
          Length = 515

 Score = 28.1 bits (61), Expect = 5.6
 Identities = 44/196 (22%), Positives = 74/196 (37%), Gaps = 28/196 (14%)

Query: 21  GPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITK-IKAVYDTNPAKFRTLQNILEVEKE 79
           G +L    HL P F C G P    I   +S    K I  ++  + A      NILE+   
Sbjct: 174 GQYLLYGFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEI--- 230

Query: 80  MYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEM---AL 136
                       L    +KRGL     + +     E +E H N  + N  K       +L
Sbjct: 231 ----------FHLGFKKIKRGL-----WGKYKLKKEHNEFHANKAKQNVAKYQSTSANSL 275

Query: 137 KKY-----HGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEEC-LEKIRLFLVNYTAT 190
           K+      +  +V+K    A+Y +   S   +      +V +E+C L++    L N  +T
Sbjct: 276 KRLPSAPDYNLLVEKQTHTAVYPSLNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEIST 335

Query: 191 IDVIYEMYTQMNAELN 206
           +      +  +++  N
Sbjct: 336 LSTSCSHFQHISSNNN 351


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
           [Homo sapiens]
          Length = 1130

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 79  EMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRV 126
           E+Y   W K   T+A+  LK     ++ FL+      ++  HPNL+++
Sbjct: 255 EVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA-VMKEIKHPNLVQL 301


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
           [Homo sapiens]
          Length = 1149

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 79  EMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRV 126
           E+Y   W K   T+A+  LK     ++ FL+      ++  HPNL+++
Sbjct: 274 EVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA-VMKEIKHPNLVQL 320


>gi|4557841 recombination activating gene 1 [Homo sapiens]
          Length = 1043

 Score = 27.3 bits (59), Expect = 9.5
 Identities = 11/37 (29%), Positives = 22/37 (59%)

Query: 106 VFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGW 142
           V++ ++CD  R E   NL+  + T+++   L++Y  W
Sbjct: 727 VYICTLCDATRLEASQNLVFHSITRSHAENLERYEVW 763


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score = 27.3 bits (59), Expect = 9.5
 Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 79  EMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRV 126
           E+Y   W K   T+A+  LK     ++ FL+      ++  HPNL+++
Sbjct: 286 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA-VMKEIKHPNLVQL 332


>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
          Length = 1182

 Score = 27.3 bits (59), Expect = 9.5
 Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 79  EMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRV 126
           E+Y   W K   T+A+  LK     ++ FL+      ++  HPNL+++
Sbjct: 301 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA-VMKEIKHPNLVQL 347


>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
          Length = 542

 Score = 27.3 bits (59), Expect = 9.5
 Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 79  EMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRV 126
           E+Y   W K   T+A+  LK     ++ FL+      ++  HPNL+++
Sbjct: 280 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA-VMKEIKHPNLVQL 326


>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
          Length = 1064

 Score = 27.3 bits (59), Expect = 9.5
 Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 79  EMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRV 126
           E+Y   W K   T+A+  LK     ++ FL+      ++  HPNL+++
Sbjct: 286 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA-VMKEIKHPNLVQL 332


>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
          Length = 1146

 Score = 27.3 bits (59), Expect = 9.5
 Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 79  EMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRV 126
           E+Y   W K   T+A+  LK     ++ FL+      ++  HPNL+++
Sbjct: 265 EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA-VMKEIKHPNLVQL 311


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,528,985
Number of Sequences: 37866
Number of extensions: 304033
Number of successful extensions: 576
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 567
Number of HSP's gapped (non-prelim): 19
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.