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Search of human proteins with 14042960
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
(891 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14042960 solute carrier family 4 member 11 [Homo sapiens] 1769 0.0
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 253 7e-67
gi|157671953 solute carrier family 4, anion exchanger, member 3 ... 253 7e-67
gi|156071474 solute carrier family 4, anion exchanger, member 2 ... 251 3e-66
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H... 244 3e-64
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans... 231 2e-60
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo... 231 2e-60
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans... 231 2e-60
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp... 224 2e-58
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp... 224 2e-58
gi|155722998 solute carrier family 4, sodium bicarbonate transpo... 224 2e-58
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap... 221 2e-57
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans... 216 6e-56
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa... 212 1e-54
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans... 209 9e-54
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 39 0.028
gi|47524175 fibroblast growth factor receptor 4 isoform 1 precur... 31 4.5
gi|47524173 fibroblast growth factor receptor 4 isoform 1 precur... 31 4.5
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] 31 4.5
gi|52627211 olfactory receptor, family 9, subfamily G, member 4 ... 30 7.6
>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
Length = 891
Score = 1769 bits (4581), Expect = 0.0
Identities = 891/891 (100%), Positives = 891/891 (100%)
Query: 1 MSQVGGRGDRCTQEVQGLVHGAGDLSASLAENSPTMSQNGYFEDSSYYKCDTDDTFEARE 60
MSQVGGRGDRCTQEVQGLVHGAGDLSASLAENSPTMSQNGYFEDSSYYKCDTDDTFEARE
Sbjct: 1 MSQVGGRGDRCTQEVQGLVHGAGDLSASLAENSPTMSQNGYFEDSSYYKCDTDDTFEARE 60
Query: 61 EILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNF 120
EILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNF
Sbjct: 61 EILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHTSRKYLKLKNF 120
Query: 121 KEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLF 180
KEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLF
Sbjct: 121 KEEIRAHRDLDGFLAQASIVLNETATSLDNVLRTMLRRFARDPDNNEPNCNLDLLMAMLF 180
Query: 181 TDAGAPMRGKVHLLSDTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNW 240
TDAGAPMRGKVHLLSDTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNW
Sbjct: 181 TDAGAPMRGKVHLLSDTIQGVTATVTGVRYQQSWLCIICTMKALQKRHVCISRLVRPQNW 240
Query: 241 GENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 300
GENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH
Sbjct: 241 GENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 300
Query: 301 QRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLD 360
QRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLD
Sbjct: 301 QRQLLTMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIREDIARRFPLYPLD 360
Query: 361 FTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLL 420
FTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLL
Sbjct: 361 FTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLL 420
Query: 421 YALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLS 480
YALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLS
Sbjct: 421 YALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLS 480
Query: 481 LVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGL 540
LVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGL
Sbjct: 481 LVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGL 540
Query: 541 GASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYL 600
GASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYL
Sbjct: 541 GASLNASLHTALNASFLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYL 600
Query: 601 HPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSG 660
HPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSG
Sbjct: 601 HPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSG 660
Query: 661 AMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHA 720
AMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHA
Sbjct: 661 AMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHA 720
Query: 721 AYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIP 780
AYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIP
Sbjct: 721 AYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIP 780
Query: 781 KPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQL 840
KPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQL
Sbjct: 781 KPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQL 840
Query: 841 LLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP 891
LLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP
Sbjct: 841 LLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRIIEAKYLDVMDAEHRP 891
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 253 bits (645), Expect = 7e-67
Identities = 200/690 (28%), Positives = 328/690 (47%), Gaps = 78/690 (11%)
Query: 247 VRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAF---------RQKLLETRTE------ 291
VRF+ ++L P ++ E+ R+ AT+ SD F RQ LL +E
Sbjct: 552 VRFLFVMLGPSH--TSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSI 609
Query: 292 ----------EEFKEALVHQRQLLT-----------MVSHGPVAPRTKERSTVSLPAHRH 330
+ + QR+LL M + G KE S +
Sbjct: 610 VIPPSEVEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEAT 669
Query: 331 PEP-PKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLP 389
PE P + FG G+ D+ RR+P YP D D + + + LF+YFA L P
Sbjct: 670 PEDDPLLRTGSVFG-GLVRDVRRRYPHYPSDLRDALHSQ------CVAAVLFIYFAALSP 722
Query: 390 TIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVIC 449
I FG L E T+G + V + I ++ G+L++L QPL+++ + PL ++ + C
Sbjct: 723 AITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFC 782
Query: 450 DDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKG 509
DL++ + W GLW F+ S ++ T+EI A IS+ F+ +
Sbjct: 783 RAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYK 842
Query: 510 TVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHS 569
K+F + H L ++ L SL+A L N S L PTE P + +
Sbjct: 843 LYKVFTE----HPLLPFYPPE-------GALEGSLDAGLEP--NGSAL-PPTEGPPSPRN 888
Query: 570 GQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFR 629
TA+LSL++MLGT ++ + L +F+ S +L R I+ D +PI++L L+ +
Sbjct: 889 QPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLV-DYSIT 947
Query: 630 EIEMSKFRY-------NPSESPFAMAQIQSL----SLRAVSGAMGLGFLLSMLFFIEQNL 678
+ K +P + + + + S V+ A+ L+ +L F+E +
Sbjct: 948 DTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVP-ALLVLILIFMETQI 1006
Query: 679 VAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEER 738
A +V+ RL+KG+ +H DLLL+ + LFGLPW+ AA S HV AL ++
Sbjct: 1007 TALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTA 1066
Query: 739 VENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDG 798
+ G I V+E R+T + + LVGLS+++ V L+ IP VL+G+FLY+ +TSL G
Sbjct: 1067 IAPGD-KPQIQEVREQRVTGVLIASLVGLSIVMGAV-LRRIPLAVLFGIFLYMGVTSLSG 1124
Query: 799 NQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIF 858
QL QR+ L+L +P Y+ +V ++H FT +Q+ + LL ++ + F
Sbjct: 1125 IQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTA---ASLAF 1181
Query: 859 PLIMIAMIPIRYILLPRIIEAKYLDVMDAE 888
P +++ +P+R+ LLPR+ + + L +D+E
Sbjct: 1182 PFLLLLTVPLRHCLLPRLFQDRELQALDSE 1211
>gi|157671953 solute carrier family 4, anion exchanger, member 3
isoform 2 [Homo sapiens]
Length = 1259
Score = 253 bits (645), Expect = 7e-67
Identities = 200/690 (28%), Positives = 328/690 (47%), Gaps = 78/690 (11%)
Query: 247 VRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAF---------RQKLLETRTE------ 291
VRF+ ++L P ++ E+ R+ AT+ SD F RQ LL +E
Sbjct: 579 VRFLFVMLGPSH--TSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSI 636
Query: 292 ----------EEFKEALVHQRQLLT-----------MVSHGPVAPRTKERSTVSLPAHRH 330
+ + QR+LL M + G KE S +
Sbjct: 637 VIPPSEVEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEAT 696
Query: 331 PEP-PKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLP 389
PE P + FG G+ D+ RR+P YP D D + + + LF+YFA L P
Sbjct: 697 PEDDPLLRTGSVFG-GLVRDVRRRYPHYPSDLRDALHSQ------CVAAVLFIYFAALSP 749
Query: 390 TIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVIC 449
I FG L E T+G + V + I ++ G+L++L QPL+++ + PL ++ + C
Sbjct: 750 AITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFC 809
Query: 450 DDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKG 509
DL++ + W GLW F+ S ++ T+EI A IS+ F+ +
Sbjct: 810 RAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYK 869
Query: 510 TVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPTELPSATHS 569
K+F + H L ++ L SL+A L N S L PTE P + +
Sbjct: 870 LYKVFTE----HPLLPFYPPE-------GALEGSLDAGLEP--NGSAL-PPTEGPPSPRN 915
Query: 570 GQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFR 629
TA+LSL++MLGT ++ + L +F+ S +L R I+ D +PI++L L+ +
Sbjct: 916 QPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLV-DYSIT 974
Query: 630 EIEMSKFRY-------NPSESPFAMAQIQSL----SLRAVSGAMGLGFLLSMLFFIEQNL 678
+ K +P + + + + S V+ A+ L+ +L F+E +
Sbjct: 975 DTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVP-ALLVLILIFMETQI 1033
Query: 679 VAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEER 738
A +V+ RL+KG+ +H DLLL+ + LFGLPW+ AA S HV AL ++
Sbjct: 1034 TALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTA 1093
Query: 739 VENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDG 798
+ G I V+E R+T + + LVGLS+++ V L+ IP VL+G+FLY+ +TSL G
Sbjct: 1094 IAPGD-KPQIQEVREQRVTGVLIASLVGLSIVMGAV-LRRIPLAVLFGIFLYMGVTSLSG 1151
Query: 799 NQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIF 858
QL QR+ L+L +P Y+ +V ++H FT +Q+ + LL ++ + F
Sbjct: 1152 IQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTA---ASLAF 1208
Query: 859 PLIMIAMIPIRYILLPRIIEAKYLDVMDAE 888
P +++ +P+R+ LLPR+ + + L +D+E
Sbjct: 1209 PFLLLLTVPLRHCLLPRLFQDRELQALDSE 1238
>gi|156071474 solute carrier family 4, anion exchanger, member 2
(erythrocyte membrane protein band 3-like 1) [Homo
sapiens]
Length = 1241
Score = 251 bits (640), Expect = 3e-66
Identities = 205/710 (28%), Positives = 323/710 (45%), Gaps = 108/710 (15%)
Query: 247 VRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEAL-------- 298
VRF+ L+L P + E+ R+ +T+ SD F + E+ A+
Sbjct: 553 VRFLFLLLGPSS--ANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSV 610
Query: 299 ------VHQRQLLTMVSHGPVAP-RTKERSTVSLPAHRHPEPPKCKDFV----------- 340
V +LL V+H + +E LP EP +D
Sbjct: 611 VLPPSEVQGEELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAA 670
Query: 341 ----------PFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPT 390
PFG G+ D+ RR+P Y DF D + + + +F+YFA L P
Sbjct: 671 EDDPLRRTGRPFG-GLIRDVRRRYPHYLSDFRDALDPQ------CLAAVIFIYFAALSPA 723
Query: 391 IAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICD 450
I FG L E T I V + I ++ G+++ L QPL+++ + PL ++ + C
Sbjct: 724 ITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCS 783
Query: 451 DYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGT 510
L++ W G W F L S ++ R T+EI A IS+ F+ +
Sbjct: 784 SNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKL 843
Query: 511 VKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFL-ASPTELPS---- 565
VKIF ++ L G AS ++ + N ++ A PT P
Sbjct: 844 VKIFQEH------------------PLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSL 885
Query: 566 ATHSGQA-------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVL 618
A SGQ TA+LSL++M GT ++ + L +FK S + +R ++ D +PIA+L
Sbjct: 886 AGQSGQGKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAIL 945
Query: 619 AFSLI---------------SSHGFREIEMSKFRYNP--SESPFAMAQIQSLSLRAVSGA 661
L+ S E + NP +SPF + + + L A+
Sbjct: 946 IMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAI--- 1002
Query: 662 MGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAA 721
L+ +L F+E + +++ E L KG+ +H DLLL+ + +LFGLPW+ AA
Sbjct: 1003 -----LVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAA 1057
Query: 722 YPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPK 781
S H AL ++ + V G I VKE R+T L ++LVGLS+++ + L+ IP
Sbjct: 1058 TVRSVTHANALTVMSKAVAPGD-KPKIQEVKEQRVTGLLVALLVGLSIVIGDL-LRQIPL 1115
Query: 782 PVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLL 841
VL+G+FLY+ +TSL+G Q +R+ LLL +P Y+++V ++H FT LQ+L L
Sbjct: 1116 AVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLA 1175
Query: 842 LLCAFGMSSLPYMKMIFPLIMIAMIPIRYILLPRII---EAKYLDVMDAE 888
LL A ++ + FP I+I +P+R ++L RI E K LD +AE
Sbjct: 1176 LLWAVMSTA---ASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAE 1222
>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
sapiens]
Length = 911
Score = 244 bits (622), Expect = 3e-64
Identities = 193/680 (28%), Positives = 314/680 (46%), Gaps = 90/680 (13%)
Query: 247 VRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV------- 299
+RF+ ++L P T ++ R AT+ S+ FR ++ E +L
Sbjct: 262 IRFLFVLLGPEAPHIDYT--QLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSL 319
Query: 300 --------HQRQLLTMVSHGPVAPRTKERSTVSLPA------------HRHPEPPKCKDF 339
++ LL++V PV R S PA + P+ P +
Sbjct: 320 VLPPTDAPSEQALLSLV---PVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQQTG 376
Query: 340 VPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDE 399
FG G+ DI RR+P Y D TD + + +F+YFA L P I FG L E
Sbjct: 377 QLFG-GLVRDIRRRYPYYLSDITDAFSPQ------VLAAVIFIYFAALSPAITFGGLLGE 429
Query: 400 NTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSF 459
T + V + + ++ G+L+AL QPL+++ + PL ++ + C+ L++
Sbjct: 430 KTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVG 489
Query: 460 YAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYY 519
W G W + L F S ++ R T+EI + IS+ F+ + +KIF
Sbjct: 490 RVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIF----- 544
Query: 520 GHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPT-ELPSATHSGQATAVLSL 578
D+ ++T + N + P LP+ TA+LSL
Sbjct: 545 ----QDHPLQKTYNY------------------NVLMVPKPQGPLPN-------TALLSL 575
Query: 579 LIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFR- 637
++M GT + L +FK S Y +R ++ D +PI++L L+ ++ K
Sbjct: 576 VLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFF-IQDTYTQKLSV 634
Query: 638 ---YNPSESPFAMAQIQSLSLRA-----VSGAMGL-GFLLSMLFFIEQNLVAALVNAPEN 688
+ S S I L LR+ + A L L+ +L F+E + +V+ PE
Sbjct: 635 PDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPER 694
Query: 689 RLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTI 748
++VKG+ +H DLLL+ + +LFG+PW+ A S H AL ++ + G I
Sbjct: 695 KMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQ-I 753
Query: 749 VNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALL 808
VKE R++ L +VLVGLS+L+ P+ L IP VL+G+FLY+ +TSL G QL R+ LL
Sbjct: 754 QEVKEQRISGLLVAVLVGLSILMEPI-LSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLL 812
Query: 809 LKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPI 868
K +P Y++RV ++H FTG+Q++ L +L + + S P + P ++I +P+
Sbjct: 813 FKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVL--WVVKSTP-ASLALPFVLILTVPL 869
Query: 869 RYILLPRIIEAKYLDVMDAE 888
R +LLP I L +DA+
Sbjct: 870 RRVLLPLIFRNVELQCLDAD 889
>gi|197927160 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 3 [Homo sapiens]
Length = 1094
Score = 231 bits (589), Expect = 2e-60
Identities = 184/681 (27%), Positives = 310/681 (45%), Gaps = 74/681 (10%)
Query: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307
RF+ ++L P K+ E+ R AT+ SD F + + + + + +
Sbjct: 322 RFLFILLGPKG--KAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 379
Query: 308 VSHGPVAPRTKERSTVSLPA-------------------------HRHPEPPKCKDFVPF 342
+ G P + SLP+ H C++
Sbjct: 380 LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 439
Query: 343 GK---GIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDE 399
G+ G+ +DI R+ P + DF D + + ++ LF+Y A + I FG L +
Sbjct: 440 GRFCGGLIKDIKRKAPFFASDFYDALNIQA------LSAILFIYLATVTNAITFGGLLGD 493
Query: 400 NTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSF 459
TD V ++ G ++ G ++ LF+GQPL IL +T P+ ++ +++ D + D+ F
Sbjct: 494 ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 553
Query: 460 YAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-Y 518
W GLW++F + + S ++ F R TEE + IS F+ DA K +K+ Y
Sbjct: 554 RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 613
Query: 519 YGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLA--SPTELPSATHSGQA---- 572
++ Y+T + + V A+++ S T L +L S T++ T A
Sbjct: 614 NSNFKVGYNTLFSCTCVPPDP--ANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSK 671
Query: 573 --------------------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCA 612
++S ++ LGT L +FK SPY R+++SD A
Sbjct: 672 KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 731
Query: 613 LPIAVLAF----SLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLL 668
+ +++L F +L+ + I S+F+ + + A L+
Sbjct: 732 IILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLV 791
Query: 669 SMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLH 728
++L F++Q + A +VN E++L KG YH DL +AI+ SL LPW AA S H
Sbjct: 792 TILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAH 851
Query: 729 VRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLF 788
+ +L + E G + V+E R+T +L GLS+ + P+ L++IP PVLYG+F
Sbjct: 852 IDSLKMETETSAPGE-QPKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVF 909
Query: 789 LYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGM 848
LY+ + SL+G Q + R+ LLL P Y+R VP R++H FT LQVL L LL
Sbjct: 910 LYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKS 969
Query: 849 SSLPYMKMIFPLIMIAMIPIR 869
+ +IFP++++A++ +R
Sbjct: 970 T---VAAIIFPVMILALVAVR 987
>gi|4507025 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 2 [Homo sapiens]
Length = 1035
Score = 231 bits (589), Expect = 2e-60
Identities = 184/681 (27%), Positives = 310/681 (45%), Gaps = 74/681 (10%)
Query: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307
RF+ ++L P K+ E+ R AT+ SD F + + + + + +
Sbjct: 278 RFLFILLGPKG--KAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 335
Query: 308 VSHGPVAPRTKERSTVSLPA-------------------------HRHPEPPKCKDFVPF 342
+ G P + SLP+ H C++
Sbjct: 336 LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 395
Query: 343 GK---GIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDE 399
G+ G+ +DI R+ P + DF D + + ++ LF+Y A + I FG L +
Sbjct: 396 GRFCGGLIKDIKRKAPFFASDFYDALNIQA------LSAILFIYLATVTNAITFGGLLGD 449
Query: 400 NTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSF 459
TD V ++ G ++ G ++ LF+GQPL IL +T P+ ++ +++ D + D+ F
Sbjct: 450 ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 509
Query: 460 YAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-Y 518
W GLW++F + + S ++ F R TEE + IS F+ DA K +K+ Y
Sbjct: 510 RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 569
Query: 519 YGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLA--SPTELPSATHSGQA---- 572
++ Y+T + + V A+++ S T L +L S T++ T A
Sbjct: 570 NSNFKVGYNTLFSCTCVPPDP--ANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSK 627
Query: 573 --------------------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCA 612
++S ++ LGT L +FK SPY R+++SD A
Sbjct: 628 KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 687
Query: 613 LPIAVLAF----SLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLL 668
+ +++L F +L+ + I S+F+ + + A L+
Sbjct: 688 IILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLV 747
Query: 669 SMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLH 728
++L F++Q + A +VN E++L KG YH DL +AI+ SL LPW AA S H
Sbjct: 748 TILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAH 807
Query: 729 VRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLF 788
+ +L + E G + V+E R+T +L GLS+ + P+ L++IP PVLYG+F
Sbjct: 808 IDSLKMETETSAPGE-QPKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVF 865
Query: 789 LYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGM 848
LY+ + SL+G Q + R+ LLL P Y+R VP R++H FT LQVL L LL
Sbjct: 866 LYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKS 925
Query: 849 SSLPYMKMIFPLIMIAMIPIR 869
+ +IFP++++A++ +R
Sbjct: 926 T---VAAIIFPVMILALVAVR 943
>gi|148596928 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 1 [Homo sapiens]
Length = 1079
Score = 231 bits (589), Expect = 2e-60
Identities = 184/681 (27%), Positives = 310/681 (45%), Gaps = 74/681 (10%)
Query: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307
RF+ ++L P K+ E+ R AT+ SD F + + + + + +
Sbjct: 322 RFLFILLGPKG--KAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 379
Query: 308 VSHGPVAPRTKERSTVSLPA-------------------------HRHPEPPKCKDFVPF 342
+ G P + SLP+ H C++
Sbjct: 380 LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 439
Query: 343 GK---GIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDE 399
G+ G+ +DI R+ P + DF D + + ++ LF+Y A + I FG L +
Sbjct: 440 GRFCGGLIKDIKRKAPFFASDFYDALNIQA------LSAILFIYLATVTNAITFGGLLGD 493
Query: 400 NTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSF 459
TD V ++ G ++ G ++ LF+GQPL IL +T P+ ++ +++ D + D+ F
Sbjct: 494 ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 553
Query: 460 YAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-Y 518
W GLW++F + + S ++ F R TEE + IS F+ DA K +K+ Y
Sbjct: 554 RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 613
Query: 519 YGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLA--SPTELPSATHSGQA---- 572
++ Y+T + + V A+++ S T L +L S T++ T A
Sbjct: 614 NSNFKVGYNTLFSCTCVPPDP--ANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSK 671
Query: 573 --------------------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCA 612
++S ++ LGT L +FK SPY R+++SD A
Sbjct: 672 KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 731
Query: 613 LPIAVLAF----SLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLL 668
+ +++L F +L+ + I S+F+ + + A L+
Sbjct: 732 IILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLV 791
Query: 669 SMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLH 728
++L F++Q + A +VN E++L KG YH DL +AI+ SL LPW AA S H
Sbjct: 792 TILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAH 851
Query: 729 VRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLF 788
+ +L + E G + V+E R+T +L GLS+ + P+ L++IP PVLYG+F
Sbjct: 852 IDSLKMETETSAPGE-QPKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVF 909
Query: 789 LYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGM 848
LY+ + SL+G Q + R+ LLL P Y+R VP R++H FT LQVL L LL
Sbjct: 910 LYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKS 969
Query: 849 SSLPYMKMIFPLIMIAMIPIR 869
+ +IFP++++A++ +R
Sbjct: 970 T---VAAIIFPVMILALVAVR 987
>gi|90403614 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform a [Homo sapiens]
Length = 1093
Score = 224 bits (572), Expect = 2e-58
Identities = 184/673 (27%), Positives = 315/673 (46%), Gaps = 66/673 (9%)
Query: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307
RF+ ++L P + + E+ R+ AT+ +D F + + ++ + +T+
Sbjct: 338 RFLFILLGP--VGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTV 395
Query: 308 VSHGPVAPRTKERSTVSLPA---------------HRHPEP------PKCKDFVPFGKGI 346
+ G P + ++P+ H EP P+ + G+
Sbjct: 396 LPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGL 455
Query: 347 REDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAID 406
DI R+ P Y D+ D + + + + LFLY AC+ P I FG L E T+G I
Sbjct: 456 VLDIKRKAPWYWSDYRDALSLQ------CLASFLFLYCACMSPVITFGGLLGEATEGRIS 509
Query: 407 VQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLW 466
+++ G S+ G+ Y+LF+GQ L IL +T P+ ++ +++ C DY L + S A GLW
Sbjct: 510 AIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLW 569
Query: 467 NSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-YYGH---- 521
+F + + S ++ R TEE A I I F+ +A++ + + Y + H
Sbjct: 570 TAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLD 629
Query: 522 YLDDYHTKRT---------------SSLVSLSGLGASLNASLHTALNASFLASPTELPSA 566
+L Y+ + T ++V+ A+L S ++ F+ S +
Sbjct: 630 HLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGS-----AC 684
Query: 567 THSGQATAVL---SLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLI 623
H G T + S ++ T L TL FK S Y VR ++SD A+ + + +I
Sbjct: 685 GHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVII 744
Query: 624 S-SHGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLV 679
G ++ S F+ + + + I V A+ L ++L F++Q +
Sbjct: 745 DFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQIT 804
Query: 680 AALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERV 739
A ++N E++L KG YH DLL++AI+ S+ GLPW AA S HV +L L E
Sbjct: 805 AVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECS 864
Query: 740 ENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGN 799
G + ++E R+T L VL+G S+ + + L++IP PVLYG+FLY+ ++SL G
Sbjct: 865 APGE-QPKFLGIREQRVTGLMIFVLMGCSVFMTAI-LKFIPMPVLYGVFLYMGVSSLQGI 922
Query: 800 QLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFP 859
Q R+ L P Y+R VP RK+H FT +Q+ L+LL S ++FP
Sbjct: 923 QFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASP---AAIVFP 979
Query: 860 LIMIAMIPIRYIL 872
++++A++ +R ++
Sbjct: 980 MMVLALVFVRKVM 992
>gi|90568034 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform b [Homo sapiens]
Length = 1044
Score = 224 bits (572), Expect = 2e-58
Identities = 184/673 (27%), Positives = 315/673 (46%), Gaps = 66/673 (9%)
Query: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307
RF+ ++L P + + E+ R+ AT+ +D F + + ++ + +T+
Sbjct: 338 RFLFILLGP--VGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTV 395
Query: 308 VSHGPVAPRTKERSTVSLPA---------------HRHPEP------PKCKDFVPFGKGI 346
+ G P + ++P+ H EP P+ + G+
Sbjct: 396 LPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGL 455
Query: 347 REDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAID 406
DI R+ P Y D+ D + + + + LFLY AC+ P I FG L E T+G I
Sbjct: 456 VLDIKRKAPWYWSDYRDALSLQ------CLASFLFLYCACMSPVITFGGLLGEATEGRIS 509
Query: 407 VQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLW 466
+++ G S+ G+ Y+LF+GQ L IL +T P+ ++ +++ C DY L + S A GLW
Sbjct: 510 AIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLW 569
Query: 467 NSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-YYGH---- 521
+F + + S ++ R TEE A I I F+ +A++ + + Y + H
Sbjct: 570 TAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLD 629
Query: 522 YLDDYHTKRT---------------SSLVSLSGLGASLNASLHTALNASFLASPTELPSA 566
+L Y+ + T ++V+ A+L S ++ F+ S +
Sbjct: 630 HLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGS-----AC 684
Query: 567 THSGQATAVL---SLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLI 623
H G T + S ++ T L TL FK S Y VR ++SD A+ + + +I
Sbjct: 685 GHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVII 744
Query: 624 S-SHGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLV 679
G ++ S F+ + + + I V A+ L ++L F++Q +
Sbjct: 745 DFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQIT 804
Query: 680 AALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERV 739
A ++N E++L KG YH DLL++AI+ S+ GLPW AA S HV +L L E
Sbjct: 805 AVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECS 864
Query: 740 ENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGN 799
G + ++E R+T L VL+G S+ + + L++IP PVLYG+FLY+ ++SL G
Sbjct: 865 APGE-QPKFLGIREQRVTGLMIFVLMGCSVFMTAI-LKFIPMPVLYGVFLYMGVSSLQGI 922
Query: 800 QLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFP 859
Q R+ L P Y+R VP RK+H FT +Q+ L+LL S ++FP
Sbjct: 923 QFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASP---AAIVFP 979
Query: 860 LIMIAMIPIRYIL 872
++++A++ +R ++
Sbjct: 980 MMVLALVFVRKVM 992
>gi|155722998 solute carrier family 4, sodium bicarbonate
transporter-like, member 10 [Homo sapiens]
Length = 1088
Score = 224 bits (572), Expect = 2e-58
Identities = 185/687 (26%), Positives = 314/687 (45%), Gaps = 56/687 (8%)
Query: 229 VCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLET 288
V +S V Q E RF+ ++L P + + E+ R+ AT+ +D F +
Sbjct: 320 VRLSPAVLLQGLAEVPIPTRFLFILLGP--LGKGQQYHEIGRSIATLMTDEVFHDVAYKA 377
Query: 289 RTEEEFKEALVHQRQLLTMVSHGPVAPRTKERSTVSLP---------------AHRHPEP 333
+ + + +T++ G P + ++P AH EP
Sbjct: 378 KDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEP 437
Query: 334 ------PKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACL 387
P+ + G+ DI R+ P + DF D + + + LFLY AC+
Sbjct: 438 HGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQ------CLASFLFLYCACM 491
Query: 388 LPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRV 447
P I FG L E T+G I +++ G S+ G+ Y+LF GQPL IL +T P+ ++ +++
Sbjct: 492 SPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFK 551
Query: 448 ICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAV 507
C +Y L + S A GLW + + + S ++ R TEE A I I F+ +A+
Sbjct: 552 FCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEAL 611
Query: 508 KGTVKIFWKYYYGHYLD-DYHTKRTSSLVSLSGLGASL-------NASLHTALNASFLAS 559
+ ++ Y + D + T+ + + V N S + + S
Sbjct: 612 EKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVS 671
Query: 560 PTELPSATHSGQATA----------VLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILS 609
+ + G+A S+++ T+ L TL QFK S Y VR I+S
Sbjct: 672 ECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVS 731
Query: 610 DCALPIAVLAFSLIS-SHGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLG 665
D A+ + +L LI + G ++ S F+ + + + + V A+
Sbjct: 732 DFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPA 791
Query: 666 FLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHS 725
L ++L F++Q + A ++N E++L KG YH DLL++A++ S+ GLPW AA S
Sbjct: 792 LLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLS 851
Query: 726 PLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLY 785
HV +L L E G + ++E R+T L +L+G S+ + + L++IP PVLY
Sbjct: 852 ITHVNSLKLESECSAPGE-QPKFLGIREQRVTGLMIFILMGSSVFMTSI-LKFIPMPVLY 909
Query: 786 GLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCA 845
G+FLY+ +SL G Q R+ L P Y+R VP RK+H FT +Q+ L LL
Sbjct: 910 GVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWI 969
Query: 846 FGMSSLPYMKMIFPLIMIAMIPIRYIL 872
+S ++FP++++A++ +R ++
Sbjct: 970 IKVSR---AAIVFPMMVLALVFVRKLM 993
>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
Length = 1121
Score = 221 bits (564), Expect = 2e-57
Identities = 162/560 (28%), Positives = 273/560 (48%), Gaps = 41/560 (7%)
Query: 342 FGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENT 401
F G+ DI R+ P +P DF DG ++ I+ LF+Y C+ I FG L + T
Sbjct: 494 FFGGLCLDIKRKLPWFPSDFYDGFHIQS------ISAILFIYLGCITNAITFGGLLGDAT 547
Query: 402 DGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYA 461
D V ++ G ++ G L+ LFSGQPL+IL +T P+ ++ +++ LD+ F
Sbjct: 548 DNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRL 607
Query: 462 WTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYY--- 518
W GL ++ + + S ++ R TEE + IS F+ DA+K + F KYY
Sbjct: 608 WIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF-KYYPIN 666
Query: 519 ---YGHYLDDYH-------TKRTSSLVSLSGLGASLNASLHTALNASFL--ASPTELPSA 566
+++ Y T T+ + + L NASL+ LN + L + ++
Sbjct: 667 MDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECL 726
Query: 567 THSGQAT----------AVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIA 616
++ G+ A++S ++ GT + TL +FK S Y VR +++D ++ +
Sbjct: 727 SYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFS 786
Query: 617 VLAFSLISS-HGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLF 672
+L F I + G ++ S + + + +A ++ L+++L
Sbjct: 787 ILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILI 846
Query: 673 FIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRAL 732
F++Q + A +VN EN+L K YH DL + I+ S GLPW AA S H+ +L
Sbjct: 847 FMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSL 906
Query: 733 ALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIA 792
+ E G + V+E R+T + +L G+S+ L P+ L+ IP PVLYG+FLY+
Sbjct: 907 KMETETSAPGE-QPQFLGVREQRVTGIIVFILTGISVFLAPI-LKCIPLPVLYGVFLYMG 964
Query: 793 LTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLP 852
+ SL+G Q +R L L P ++R VP R+IH FT ++Q+L L +
Sbjct: 965 VASLNGIQFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFT---LVQILCLAVLWILKST 1021
Query: 853 YMKMIFPLIMIAMIPIRYIL 872
+IFP++++ +I +R +L
Sbjct: 1022 VAAIIFPVMILGLIIVRRLL 1041
>gi|134288865 solute carrier family 4, sodium bicarbonate
cotransporter, member 7 [Homo sapiens]
Length = 1214
Score = 216 bits (551), Expect = 6e-56
Identities = 181/675 (26%), Positives = 302/675 (44%), Gaps = 68/675 (10%)
Query: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307
RF+ L+L P E+ R+ AT+ +D F + + + + +T+
Sbjct: 466 RFLFLLLGPAG--KAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTV 523
Query: 308 VSHGPVAPRTKERSTVSLP------------------------AHRHPEPPKCKDFVPFG 343
+ G P + S+P A H P + FG
Sbjct: 524 LPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPELQRTGRLFG 583
Query: 344 KGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDG 403
G+ DI R+ P + DF D + + + + LFLY AC+ P I FG L E T+G
Sbjct: 584 -GLILDIKRKAPFFLSDFKDALSLQ------CLASILFLYCACMSPVITFGGLLGEATEG 636
Query: 404 AIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWT 463
I +++ G S+ G+ Y+LF+GQPL IL +T P+ ++ +++ C DY L + S
Sbjct: 637 RISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSI 696
Query: 464 GLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHY- 522
GLW SF + + S ++ R TEE A I I F+ +A++ + Y + +
Sbjct: 697 GLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHN 756
Query: 523 ----LDDYHTKRTS---------------SLVSLSGLGASLNASLHTALNASFLASPTEL 563
L Y T ++ + + +L S L FL S
Sbjct: 757 NLDKLTSYSCVCTEPPNPSNETLAQWKKDNITAHNISWRNLTVSECKKLRGVFLGSAC-- 814
Query: 564 PSATHSGQATAVL--SLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFS 621
H VL +++ T +L L QFK Y VR +SD A+ + ++
Sbjct: 815 --GHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMV 872
Query: 622 ----LISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQN 677
L+ + KF E + ++ + + A L ++L F++Q
Sbjct: 873 TIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALLCTILIFMDQQ 932
Query: 678 LVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEE 737
+ A ++N E++L KG YH DLL++ ++ S+ GLPW AA S HV +L + E
Sbjct: 933 ITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVESE 992
Query: 738 RVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLD 797
G + ++E R+T L +L+GLS+ + V L++IP PVLYG+FLY+ ++SL
Sbjct: 993 CSAPGE-QPKFLGIREQRVTGLMIFILMGLSVFMTSV-LKFIPMPVLYGVFLYMGVSSLK 1050
Query: 798 GNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMI 857
G QL R+ L P Y+R VP K+H FT +Q+ L+LL +S+ ++
Sbjct: 1051 GIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLWVIKVSA---AAVV 1107
Query: 858 FPLIMIAMIPIRYIL 872
FP++++A++ +R ++
Sbjct: 1108 FPMMVLALVFVRKLM 1122
>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
sapiens]
Length = 1137
Score = 212 bits (539), Expect = 1e-54
Identities = 162/576 (28%), Positives = 274/576 (47%), Gaps = 57/576 (9%)
Query: 342 FGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENT 401
F G+ DI R+ P +P DF DG ++ I+ LF+Y C+ I FG L + T
Sbjct: 494 FFGGLCLDIKRKLPWFPSDFYDGFHIQS------ISAILFIYLGCITNAITFGGLLGDAT 547
Query: 402 DGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYA 461
D V ++ G ++ G L+ LFSGQPL+IL +T P+ ++ +++ LD+ F
Sbjct: 548 DNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRL 607
Query: 462 WTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYY--- 518
W GL ++ + + S ++ R TEE + IS F+ DA+K + F KYY
Sbjct: 608 WIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF-KYYPIN 666
Query: 519 ---YGHYLDDY-------HTKRTSSLVSLSGLGASLNASLHTALNASFL--ASPTELPSA 566
+++ Y T T+ + + L NASL+ LN + L + ++
Sbjct: 667 MDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECL 726
Query: 567 THSGQA----------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIA 616
++ G+ A++S ++ GT + TL +FK S Y VR +++D ++ +
Sbjct: 727 SYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFS 786
Query: 617 VLAFSLISS-HGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLF 672
+L F I + G ++ S + + + +A ++ L+++L
Sbjct: 787 ILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILI 846
Query: 673 FIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRAL 732
F++Q + A +VN EN+L K YH DL + I+ S GLPW AA S H+ +L
Sbjct: 847 FMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSL 906
Query: 733 ALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIA 792
+ E G + V+E R+T + +L G+S+ L P+ L+ IP PVLYG+FLY+
Sbjct: 907 KMETETSAPGE-QPQFLGVREQRVTGIIVFILTGISVFLAPI-LKCIPLPVLYGVFLYMG 964
Query: 793 LTSLDGNQL----------------VQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQ 836
+ SL+G Q+ +R L L P ++R VP R+IH FT
Sbjct: 965 VASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFT--- 1021
Query: 837 VLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYIL 872
++Q+L L + +IFP++++ +I +R +L
Sbjct: 1022 LVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLL 1057
>gi|151101449 solute carrier family 4, sodium bicarbonate
cotransporter, member 9 [Homo sapiens]
Length = 959
Score = 209 bits (532), Expect = 9e-54
Identities = 174/595 (29%), Positives = 272/595 (45%), Gaps = 57/595 (9%)
Query: 311 GPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGK---GIREDIARRFPLYPLDFTDGIIG 367
GP PR T + HRH + G+ G+ +D+ R+ P YP DF D +
Sbjct: 331 GPAVPRL----TSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHL 386
Query: 368 KNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQ 427
+ + L++Y A + I FG L + TDGA V ++ G ++ G + L +GQ
Sbjct: 387 Q------CFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQ 440
Query: 428 PLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFK 487
PL IL +T P+ ++ +++ DY LD+ F W G+W + F + S+++ F
Sbjct: 441 PLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFT 500
Query: 488 RSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNAS 547
R TEE IS+ F+ DAV + + Y + + L G G + +
Sbjct: 501 RFTEEGFCALISLIFIYDAVGKMLNLTHTYP----IQKPGSSAYGCLCQYPGPGGNESQW 556
Query: 548 LHTA--------------LNASFLASPT-------ELPSATHSGQATAVLSLLIMLGTLW 586
+ T +NAS L P H+ A SLL+ L + +
Sbjct: 557 IRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFF 616
Query: 587 LGYTLYQFKKSPYLHPCVREILSDCALPIAVL------AFSLISSHGF---REIEMSKFR 637
L K S + VR+ LSD + +A+L AF +++ RE + +
Sbjct: 617 FAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREFKPTLPG 676
Query: 638 YNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYH 697
SPF A S+ A A+ LLS+L F++Q + A ++N E RL KG +H
Sbjct: 677 RGWLVSPFG-ANPWWWSVAAALPAL----LLSILIFMDQQITAVILNRMEYRLQKGAGFH 731
Query: 698 WDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLT 757
DL +A++ S GLPW +A S H+ +L G + ++E RLT
Sbjct: 732 LDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGE-RPNFLGIREQRLT 790
Query: 758 SLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPP 817
L +L G S+ L PV L++IP PVLYG+FLY+ + +L Q RV LLL P
Sbjct: 791 GLVVFILTGASIFLAPV-LKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPD 849
Query: 818 THYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYIL 872
+R VP ++H FT +Q+ L LL + + S P +IFPL+++ ++ +R L
Sbjct: 850 LLLLRHVPLTRVHLFTAIQLACLGLL--WIIKSTP-AAIIFPLMLLGLVGVRKAL 901
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 38.5 bits (88), Expect = 0.028
Identities = 39/187 (20%), Positives = 69/187 (36%), Gaps = 33/187 (17%)
Query: 51 DTDDTFEAREEILGDEAFDTANSSIVSGESIRFFVNVNLEMQATNTENEATSGGCVLLHT 110
D D + E LG A D + +GE++ + E+ + N E T+ G + +
Sbjct: 985 DASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEK 1044
Query: 111 SRKYLKLKNFKEE--------------------IRAHRDLDGFLAQASIVLNETATSLDN 150
LK + + E I + +D A + + +T +LD
Sbjct: 1045 GLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDG 1104
Query: 151 VLRTMLRRFARDPDN------------NEPNCNLDLLMAMLFTDAGAPMRGKVHLLSDTI 198
+L M + + D + + N L +M+ L + RG +HLL +I
Sbjct: 1105 LLHLMDQPLSVDEEGLVLLEQKLSRAKTQINSQLRPMMSEL-EERARQQRGHLHLLETSI 1163
Query: 199 QGVTATV 205
G+ A V
Sbjct: 1164 DGILADV 1170
>gi|47524175 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 31.2 bits (69), Expect = 4.5
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 5/123 (4%)
Query: 661 AMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHA 720
++GL + + L + + APE R Y L LA++ L+ +H
Sbjct: 338 SIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHG 397
Query: 721 AYPHSPLHVRALALV----EERVENGHIYDTIVN-VKETRLTSLGASVLVGLSLLLLPVP 775
+P P V+ L+ + +E+G + + V+ RL+S G ++L GL L LP+
Sbjct: 398 RHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLD 457
Query: 776 LQW 778
W
Sbjct: 458 PLW 460
>gi|47524173 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 31.2 bits (69), Expect = 4.5
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 5/123 (4%)
Query: 661 AMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHA 720
++GL + + L + + APE R Y L LA++ L+ +H
Sbjct: 338 SIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHG 397
Query: 721 AYPHSPLHVRALALV----EERVENGHIYDTIVN-VKETRLTSLGASVLVGLSLLLLPVP 775
+P P V+ L+ + +E+G + + V+ RL+S G ++L GL L LP+
Sbjct: 398 RHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLD 457
Query: 776 LQW 778
W
Sbjct: 458 PLW 460
>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
Length = 1606
Score = 31.2 bits (69), Expect = 4.5
Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 11/87 (12%)
Query: 473 LYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTS 532
L A F+L V FK S EE + + +T+ + + +K+++ Y+D YH ++
Sbjct: 1339 LVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQALKVYF------YIDSYHFEQLP 1392
Query: 533 SLVSLSGLGASLNASLHTALNASFLAS 559
+ G +H L A L S
Sbjct: 1393 QRLKNGG-----GFKIHPVLFAQALES 1414
>gi|52627211 olfactory receptor, family 9, subfamily G, member 4
[Homo sapiens]
Length = 327
Score = 30.4 bits (67), Expect = 7.6
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 747 TIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVA 806
T V+++ T L +L+G S QW +P+L+G+FL + L +L GN + V
Sbjct: 12 TSVDMEVGNCTILTEFILLGFS-----ADSQW--QPILFGVFLMLYLITLSGNMTL--VI 62
Query: 807 LLLKEQTAYPPTHY 820
L+ + + P ++
Sbjct: 63 LIRTDSHLHTPMYF 76
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,208,241
Number of Sequences: 37866
Number of extensions: 1302310
Number of successful extensions: 4042
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3956
Number of HSP's gapped (non-prelim): 33
length of query: 891
length of database: 18,247,518
effective HSP length: 111
effective length of query: 780
effective length of database: 14,044,392
effective search space: 10954625760
effective search space used: 10954625760
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.