BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13994250 tektin 3 [Homo sapiens] (490 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13994250 tektin 3 [Homo sapiens] 980 0.0 gi|21389569 tektin 5 [Homo sapiens] 455 e-128 gi|21389613 tektin 4 [Homo sapiens] 290 2e-78 gi|16753231 tektin 1 [Homo sapiens] 286 2e-77 gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens] 245 6e-65 gi|16507950 tektin 2 [Homo sapiens] 191 1e-48 gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] 177 3e-44 gi|75677606 hypothetical protein LOC100132288 [Homo sapiens] 81 2e-15 gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens] 74 2e-13 gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens] 72 1e-12 gi|21735548 centrosomal protein 2 [Homo sapiens] 49 8e-06 gi|156104908 myosin heavy chain 6 [Homo sapiens] 48 2e-05 gi|62414289 vimentin [Homo sapiens] 47 4e-05 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 47 5e-05 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 47 5e-05 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 47 5e-05 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 46 7e-05 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 46 7e-05 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 45 1e-04 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 45 2e-04 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 44 3e-04 gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 43 6e-04 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 42 0.002 gi|153791839 sodium channel associated protein 1 [Homo sapiens] 42 0.002 gi|71061468 centromere protein E [Homo sapiens] 41 0.002 gi|42794779 myosin 18A isoform b [Homo sapiens] 40 0.004 gi|28416946 myosin 18A isoform a [Homo sapiens] 40 0.004 gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.005 gi|33946313 ninein isoform 4 [Homo sapiens] 40 0.006 gi|33946321 ninein isoform 5 [Homo sapiens] 40 0.006 >gi|13994250 tektin 3 [Homo sapiens] Length = 490 Score = 980 bits (2534), Expect = 0.0 Identities = 490/490 (100%), Positives = 490/490 (100%) Query: 1 MERVGCTLTTTYAHPRPTPTNFLPAISTMASSYRDRFPHSNLTHSLSLPWRPSTYYKVAS 60 MERVGCTLTTTYAHPRPTPTNFLPAISTMASSYRDRFPHSNLTHSLSLPWRPSTYYKVAS Sbjct: 1 MERVGCTLTTTYAHPRPTPTNFLPAISTMASSYRDRFPHSNLTHSLSLPWRPSTYYKVAS 60 Query: 61 NSPSVAPYCTRSQRVSENTMLPFVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHNSEKL 120 NSPSVAPYCTRSQRVSENTMLPFVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHNSEKL Sbjct: 61 NSPSVAPYCTRSQRVSENTMLPFVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHNSEKL 120 Query: 121 RVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKR 180 RVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKR Sbjct: 121 RVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKR 180 Query: 181 LERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKA 240 LERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKA Sbjct: 181 LERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKA 240 Query: 241 IAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESW 300 IAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESW Sbjct: 241 IAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESW 300 Query: 301 AKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNK 360 AKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNK Sbjct: 301 AKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNK 360 Query: 361 IQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRL 420 IQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRL Sbjct: 361 IQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRL 420 Query: 421 VNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKSY 480 VNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKSY Sbjct: 421 VNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKSY 480 Query: 481 PNTLRLVGFC 490 PNTLRLVGFC Sbjct: 481 PNTLRLVGFC 490 >gi|21389569 tektin 5 [Homo sapiens] Length = 485 Score = 455 bits (1170), Expect = e-128 Identities = 246/492 (50%), Positives = 333/492 (67%), Gaps = 13/492 (2%) Query: 1 MERVGCTLTTTYAHPRPT-PTNFLPAIST--MASSYRDRF-PHSNLTHSLSLPWRPSTYY 56 ME +G T T +Y P+ LPA+ + Y+ + P +S WRPS +Y Sbjct: 1 MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNS----WRPSLFY 56 Query: 57 KVASNSPSVAPYCTRSQRVSENTMLPFVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHN 116 K+A N + T + R T+LP + R+ F+RY+P DW +SN + + SR Sbjct: 57 KIA-NVQTCPDESTSTLRPP--TILPTL--RSALFSRYSPHDWDQSNQLQVRGAEASRLW 111 Query: 117 SEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTD 176 + +L D+ RL+QDK Q T + Q T +NLG+R++DIGFWKSE+ +ELD ++ E L Sbjct: 112 ASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLET 171 Query: 177 VKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLH 236 VK+RLE A E PLQVA ECL+HREKR+GIDLVHD VE L+ EVD + CCQE+M+ Sbjct: 172 VKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKL 231 Query: 237 LDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSV 296 + Q+ NR +QH LE+DL DK +A ID+KC +LRNTSD + +F G+E++D T+SV Sbjct: 232 AQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISV 291 Query: 297 PESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETAD 356 PE+WAKF++DNI SQ+ RA S +LR++ E+L +++MW QF NL+F RI+E D Sbjct: 292 PETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTD 351 Query: 357 AKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMA 416 KNK+QT LAKTLQEIFQ E TI ++++I K LKVAQTRL+ RTRRPN+ELCRD+ Sbjct: 352 VKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIP 411 Query: 417 QLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSM 476 QL+LVNEV +DDT+QTL+ RLR+ +DTLQ LV K LE++LA+KAN+L ID+EKCM M Sbjct: 412 QLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGM 471 Query: 477 RKSYPNTLRLVG 488 RK++P T RLVG Sbjct: 472 RKTFPCTPRLVG 483 >gi|21389613 tektin 4 [Homo sapiens] Length = 435 Score = 290 bits (742), Expect = 2e-78 Identities = 160/398 (40%), Positives = 242/398 (60%) Query: 92 TRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVN 151 ++Y ++W+++ Y ++ R SE+ R ++ +L + ++TQ D+T+ +GER+ Sbjct: 37 SKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQ 96 Query: 152 DIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLV 211 D WKSE+ E++ + ETN L K+RLERAL TE P + + L RE+R +LV Sbjct: 97 DTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLV 156 Query: 212 HDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKC 271 D VE +LL E + I QE +K + +A++Q+ NR + E D SDK AY ID+ C Sbjct: 157 RDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETC 216 Query: 272 HHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVV 331 + S V + S PE+ AKFT DN+ R+Q ER ASA LR ++ +L Sbjct: 217 GRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRD 276 Query: 332 TANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTA 391 T+ ++ Q + VNL+F R E DA+ K+ HL KTL+EI E + ++K+AIKDK A Sbjct: 277 TSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEA 336 Query: 392 FLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHI 451 L VAQTRL R+ RPN+ELCRD AQ RL++EV E++ ++ L+++L +AE +L++L I Sbjct: 337 PLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDI 396 Query: 452 KATLEYDLAVKANSLYIDQEKCMSMRKSYPNTLRLVGF 489 +LE D+A NSL+ID++KCM+ R YP L+L G+ Sbjct: 397 HMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGY 434 >gi|16753231 tektin 1 [Homo sapiens] Length = 418 Score = 286 bits (733), Expect = 2e-77 Identities = 145/389 (37%), Positives = 233/389 (59%) Query: 93 RYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVND 152 ++ P +W+ +N Y ++ R SE+L ++ RL+ + + TRK+Q+D + L +R+ + Sbjct: 10 KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEE 69 Query: 153 IGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVH 212 + FWK E+ +L++++ T+ L K RLE+AL + PL + CL +REKR+GIDLVH Sbjct: 70 VQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVH 129 Query: 213 DEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCH 272 D VE +L+ E + I + L++A Q+ NR++++ LEKDL DK A IDD C Sbjct: 130 DTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICF 189 Query: 273 HLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVT 332 L N S + Y R++ E W F+ N+ ++ +R S L+ ++ +L T Sbjct: 190 SLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQT 249 Query: 333 ANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAF 392 AN++ Q + V+ +F N + +T DA++K+ HLAK ++EI E I +++KAI D+ Sbjct: 250 ANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGP 309 Query: 393 LKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIK 452 KVA TRL+ RT RPN+ELCRD+AQ RL+ EV E+ + L++ L A+ L+ L + Sbjct: 310 AKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQ 369 Query: 453 ATLEYDLAVKANSLYIDQEKCMSMRKSYP 481 L+ ++ VK N++YID+ CM MRKS P Sbjct: 370 LALQEEIQVKENTIYIDEVLCMQMRKSIP 398 >gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens] Length = 445 Score = 245 bits (626), Expect = 6e-65 Identities = 146/388 (37%), Positives = 218/388 (56%), Gaps = 11/388 (2%) Query: 106 NYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELD 165 N E H S++L +T L Q TQ D+T +GER+ D WKSE+ E++ Sbjct: 64 NQSERELQGHESQQLAAETQALAQP-------TQQDSTCRVGERLQDTNSWKSELQREVE 116 Query: 166 EMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDT 225 + ET+ L K+RLERAL E P + + + ++ +L+ D VE +LL E + Sbjct: 117 ALAAETDLLLAQKQRLERALDAMEVPFSITTDNMQCSQRHQHTNLLRDHVETELLKEAEL 176 Query: 226 ILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKC--HHLRNTSDGVGY 283 I QE +K + +A++Q+ N E D SDK AY +D C HH ++T Sbjct: 177 IRNIQELLKRAIMQAVSQIXLNXEHMEICEMDWSDKVEAYNLDKTCGRHHSQSTEVQAHP 236 Query: 284 FRGV--ERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFN 341 ER + S PE+ KFT DN+ +Q ER SA L ++ +L T+ ++ Q + Sbjct: 237 HSTTFQERGPRSASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCD 296 Query: 342 KVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLD 401 VNL+F R E DA++K+Q HL K L+EI E + ++K+AIKDK L +AQTRL Sbjct: 297 AVNLAFGRRCEELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRLX 356 Query: 402 ERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAV 461 + RPN++LCRD AQ RLV+EV E+ +I L+++L AE +L++L I +LE D+ Sbjct: 357 LLSHRPNMQLCRDAAQFRLVSEVEELYKSITALREKLLQAEQSLRNLKDIHMSLEKDVTA 416 Query: 462 KANSLYIDQEKCMSMRKSYPNTLRLVGF 489 NS++ID++KCM+ R YP L+L G+ Sbjct: 417 MTNSVFIDRQKCMAHRTCYPTILQLAGY 444 >gi|16507950 tektin 2 [Homo sapiens] Length = 430 Score = 191 bits (486), Expect = 1e-48 Identities = 121/386 (31%), Positives = 195/386 (50%), Gaps = 1/386 (0%) Query: 93 RYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVND 152 R+ DW+ ++ + R S ++R + L + QT + D L ER++ Sbjct: 11 RFQLPDWHTNSYLLSTNAQLQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLVERIDT 70 Query: 153 IGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVH 212 + WK + L ++ E +ALT +K+ E+ L PL VA ECL RE R ID+V Sbjct: 71 VNRWKEMLDKCLTDLDAEIDALTQMKESAEQNLQAKNLPLDVAIECLTLRESRRDIDVVK 130 Query: 213 DEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCH 272 D VE +L EV+ I ++ ++ + +A QL + Q +L D K ID C Sbjct: 131 DPVEDELHKEVEVIEATKKALQQKVSQAFEQLCLLQEVQQQLNSDHRGKMETLEIDRGCL 190 Query: 273 HLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVT 332 L S + RV + + W F+ N R+++E A+ +LR+ + T Sbjct: 191 SLNLRSPNISLKVDPTRVPDGSTTLQQWDDFSRFNKDRAEAEMKAATELREATALTIAET 250 Query: 333 ANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAF 392 NE+ Q +F R+ E ++++ TL+EI + + I +++ ++ K Sbjct: 251 NNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLRTKLLS 310 Query: 393 LKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIK 452 LK++ TRL+ RT RPN+ELCRD AQ L +EVH+++ TI L+Q+L A+D L +L Sbjct: 311 LKLSHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQDALDALCKHL 370 Query: 453 ATLEYDLAVKANSLYIDQEKCMSMRK 478 A L+ D+A KANS+ +D KCM R+ Sbjct: 371 ARLQADIACKANSMLLD-TKCMDTRR 395 >gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] Length = 507 Score = 177 bits (448), Expect = 3e-44 Identities = 142/490 (28%), Positives = 210/490 (42%), Gaps = 123/490 (25%) Query: 106 NYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELD 165 N E H S++L + L Q TQ D+ +GER+ D+ W SE+ E++ Sbjct: 34 NQSERELQGHKSQQLAAEIQALAQP-------TQQDSKCRVGERLQDMHSWNSELQGEVE 86 Query: 166 EMIGETNALTDVKKRLERAL-----------------------------METE------- 189 + ET+ L K+RLE AL +ETE Sbjct: 87 ALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPP 146 Query: 190 APLQVARECLFHREKRMGIDLVHDEVEAQLLTE-------------------VDTILCCQ 230 AP Q + C R+ V + +E + E + I Q Sbjct: 147 APSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQ 206 Query: 231 ERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERV 290 E +K + +A++Q+ NR E D SDK AY +D+ C G R Sbjct: 207 ELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETC----------GRHRSQSTE 256 Query: 291 DATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNR 350 + S PE+ KFT DN+ R+Q ER SA L ++ +L T+ ++ Q + VNL+F R Sbjct: 257 PRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRR 316 Query: 351 IAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIE 410 E DA++K+Q HL K L+EI E + ++K+AIKDK A L +AQTRL + RPN+E Sbjct: 317 CEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNME 376 Query: 411 LCRDMAQLR--------------------------------------------------- 419 LCRD AQ R Sbjct: 377 LCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPK 436 Query: 420 LVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKS 479 LV+E+ E+ +I L ++L AE +L +L I +LE D+ NSL++D++ CM+ Sbjct: 437 LVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSLFLDRQNCMAHHTC 496 Query: 480 YPNTLRLVGF 489 YP L+L G+ Sbjct: 497 YPTILQLAGY 506 Score = 32.3 bits (72), Expect = 1.0 Identities = 25/122 (20%), Positives = 49/122 (40%) Query: 95 TPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIG 154 TP+ + N + R +S L V +++D + G R ++ Sbjct: 262 TPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELE 321 Query: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDE 214 + ++ H L +M+ E L+ A+ + EAPL +A+ L+ R ++L D Sbjct: 322 DARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNMELCRDA 381 Query: 215 VE 216 + Sbjct: 382 AQ 383 >gi|75677606 hypothetical protein LOC100132288 [Homo sapiens] Length = 129 Score = 80.9 bits (198), Expect = 2e-15 Identities = 46/108 (42%), Positives = 67/108 (62%) Query: 293 TVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIA 352 + S PE+ KFT DN+ +Q ER SA L ++ +L T+ ++ Q + VNL+F R Sbjct: 22 SASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGCRCE 81 Query: 353 ETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRL 400 E DA++K+Q HL K L+EI E + ++K+AIKDK L +AQTRL Sbjct: 82 ELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRL 129 >gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens] Length = 333 Score = 74.3 bits (181), Expect = 2e-13 Identities = 61/229 (26%), Positives = 93/229 (40%), Gaps = 64/229 (27%) Query: 106 NYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELD 165 N E H S++L +T L Q TQ D+T+ +GE++ D WKSE+ E++ Sbjct: 49 NQSEQELQGHESQQLAAETQALAQG-------TQQDSTRRVGEQLQDTHSWKSELQREVE 101 Query: 166 EMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTE--- 222 + ET+ L K+RLE AL TEAP +A + L + +L+ D VE +LL Sbjct: 102 ALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQHANLMRDHVETELLKAHPP 161 Query: 223 -------------------------VDTILC----------CQERMKLHLDKA------- 240 ++T+ C+ R H +A Sbjct: 162 APSQCLNNCFSSRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQ 221 Query: 241 ----------IAQLAANRASQHELEKDLSDKQTAYRIDDKC--HHLRNT 277 ++Q+ NR E D SDK AY +D+ C HH ++T Sbjct: 222 ELLKRAIVQAVSQIRLNREHTEICEMDWSDKVEAYNLDETCGRHHSQST 270 >gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens] Length = 254 Score = 71.6 bits (174), Expect = 1e-12 Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 7/115 (6%) Query: 106 NYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELD 165 N E H S++L +T L Q TQ D+T+ +GE++ D WKSE+ E++ Sbjct: 33 NQSERELQGHESQQLAAETQALAQG-------TQQDSTRRVGEQLQDTHSWKSELQREVE 85 Query: 166 EMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLL 220 + ET+ L K+RLE AL TEAP +A + L + +L+ D VE +LL Sbjct: 86 ALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELL 140 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 49.3 bits (116), Expect = 8e-06 Identities = 72/336 (21%), Positives = 143/336 (42%), Gaps = 24/336 (7%) Query: 126 RLIQD--KYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLER 183 +L QD K QQTR D Q L ER+ D KS++ EL ++ + + + K + E Sbjct: 1247 KLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEG 1306 Query: 184 ALMETEAPLQVARE---CLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKA 240 E+ L E L R +R + + + E +LL L Q HL A Sbjct: 1307 KQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVE---HLQAA 1363 Query: 241 IAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESW 300 + + A ++ LE+DL ++A ++ ++ +G +V ++ E+ Sbjct: 1364 VVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENL 1423 Query: 301 AKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNK 360 A T R + LR I+ L E + K L + + + + Sbjct: 1424 ALLTQTLAEREEEVET----LRGQIQEL------EKQREMQKAALELLSLDLKKRNQEVD 1473 Query: 361 IQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRL 420 +Q + +QE+ + +E + A++++ L V + ++ E + + E R++ + +L Sbjct: 1474 LQ---QEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEK--DRETQRNVLEHQL 1528 Query: 421 VNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLE 456 + E+ + D I++ + +++D + L +L + LE Sbjct: 1529 L-ELEKKDQMIESQRGQVQDLKKQLVTLECLALELE 1563 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 47.8 bits (112), Expect = 2e-05 Identities = 76/371 (20%), Positives = 151/371 (40%), Gaps = 46/371 (12%) Query: 133 QQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPL 192 Q+ + D Q ++VN + K ++ ++D++ G V+ LERA + E L Sbjct: 1002 QEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061 Query: 193 QVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIA-----QLAAN 247 ++ +E + +DL +D+++ + + Q+ K+ ++ +A +L N Sbjct: 1062 KLTQESI--------MDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKEN 1113 Query: 248 RASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDN 307 +A ELE++L ++TA K LR+ R +E + + E T Sbjct: 1114 QARIEELEEELEAERTARA---KVEKLRSDLS-----RELEEISERL---EEAGGATSVQ 1162 Query: 308 ILRSQSERAASAKLRDDIENLLV---VTANEMWNQFNKVNLSFTNRIAETADAKNKIQTH 364 I ++ A K+R D+E + TA + K + + E D +++ Sbjct: 1163 IEMNKKREAEFQKMRRDLEEATLQHEATAAAL----RKKHADSVAELGEQIDNLQRVKQK 1218 Query: 365 LAKTLQEI-FQTEMTIESIKKAIKDKTAFLKVAQTRLD---------ERTRRPNIELCRD 414 L K E + + ++++ IK K KV++T D E +R + Sbjct: 1219 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQ 1278 Query: 415 MAQLRLVNE--VHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVK---ANSLYID 469 A+L+ N ++++ + Q R Q + +K LE + K A++L Sbjct: 1279 RAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSA 1338 Query: 470 QEKCMSMRKSY 480 + C +R+ Y Sbjct: 1339 RHDCDLLREQY 1349 Score = 40.4 bits (93), Expect = 0.004 Identities = 68/375 (18%), Positives = 153/375 (40%), Gaps = 66/375 (17%) Query: 118 EKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDV 177 +KL+ + +R+ ++ ++ + + + + +D+ EI L+E G T+ ++ Sbjct: 1108 KKLKENQARI--EELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1165 Query: 178 KKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERM---- 233 K+ E + L+ A L H + H + A+L ++D + ++++ Sbjct: 1166 NKKREAEFQKMRRDLEEAT--LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEK 1223 Query: 234 ---KLHLDKAIA---QLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGV 287 KL LD + Q+ +A+ ++ + L D+ YR Sbjct: 1224 SEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYR--------------------- 1262 Query: 288 ERVDATVSVPESWAKFTDDNILRS--QSERAASAKLRDDIENLLVVTANEMWNQFNKVNL 345 V + E+ D R+ Q+E A+ ++ E L+ +Q + L Sbjct: 1263 ------VKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALI--------SQLTRGKL 1308 Query: 346 SFTNRIAETA---DAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDE 402 S+T ++ + + + K + LA LQ + +++ +++T A+ L Sbjct: 1309 SYTQQMEDLKRQLEEEGKAKNALAHALQS---ARHDCDLLREQYEEETE----AKAELQR 1361 Query: 403 RTRRPNIELC--RDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLE---Y 457 + N E+ R + + E+++ + L QRL+DAE+ ++++ ++LE + Sbjct: 1362 VLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKH 1421 Query: 458 DLAVKANSLYIDQEK 472 L + L +D E+ Sbjct: 1422 RLQNEIEDLMVDVER 1436 Score = 37.0 bits (84), Expect = 0.041 Identities = 69/394 (17%), Positives = 160/394 (40%), Gaps = 64/394 (16%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRK---TQADTTQNLGERVNDIG 154 +W + + E +S+ + L + +L ++ Y+++ + T +NL E ++D+ Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTELFKL-KNAYEESLEHLETFKRENKNLQEEISDL- 1514 Query: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE-----KRMGID 209 +L E + L V+K+LE +E ++ L+ A L H E ++ + Sbjct: 1515 ------TEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFN 1568 Query: 210 LVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHE-------LEKDLSDKQ 262 + E+E +L + + + + + +D L A S++E +E DL++ + Sbjct: 1569 QIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628 Query: 263 TAYRIDDKCHHLRNTSDGVGYFRGVERV--DATVSVPESWAKFTDD------------NI 308 H R ++ + ++ + D + + ++ + DD N+ Sbjct: 1629 I-----QLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA-VRANDDLKENIAIVERRNNL 1682 Query: 309 LRSQSERAASAKLRDDIENLL----VVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTH 364 L+++ E + + + L ++ +E + N S N+ + ++Q+ Sbjct: 1683 LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSE 1742 Query: 365 LAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEV 424 + + +QE E E KKAI D +A+ E+ ++E + + + + Sbjct: 1743 VEEAVQECRNAE---EKAKKAITDAA---MMAEELKKEQDTSAHLERMKKNMEQTIKDLQ 1796 Query: 425 HEVDDT-----------IQTLQQRLRDAEDTLQS 447 H +D+ +Q L+ R+R+ E L++ Sbjct: 1797 HRLDEAEQIALKGGKKQLQKLEARVRELEGELEA 1830 >gi|62414289 vimentin [Homo sapiens] Length = 466 Score = 47.0 bits (110), Expect = 4e-05 Identities = 92/444 (20%), Positives = 181/444 (40%), Gaps = 70/444 (15%) Query: 24 PAISTMASSYRDRFPHSNLTHSLSLPWRPSTYYKVASNSPSVAPYCTRSQRVSENTMLP- 82 P ++ SS R S T+SL RPST + ++SP Y TRS V + +P Sbjct: 18 PGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPG-GVYATRSSAVRLRSSVPG 76 Query: 83 --FVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQA 140 + + F + +++ TN + ++ +D R ++ QQ + A Sbjct: 77 VRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLE---QQNKILLA 133 Query: 141 DTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLF 200 + Q G+ + +G E E+ E+ + + LT+ K R+E +E + +A + + Sbjct: 134 ELEQLKGQGKSRLGDLYEE---EMRELRRQVDQLTNDKARVE---VERD---NLAEDIMR 184 Query: 201 HREKRMGIDLVHDEVEAQLLT---EVDTILCCQERMKLHLDKAIAQLAANRASQHEL-EK 256 REK L +E E L + +VD +L L++ + L A +L E+ Sbjct: 185 LREKLQEEMLQREEAENTLQSFRQDVDN----ASLARLDLERKVESLQEEIAFLKKLHEE 240 Query: 257 DLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERA 316 ++ + Q +I ++ H+ ++D VS P+ A D +R Q E Sbjct: 241 EIQELQA--QIQEQ--HV--------------QIDVDVSKPDLTAALRD---VRQQYESV 279 Query: 317 ASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTE 376 A+ L++ E W + ++ A+ ++A N+ L + QE + Sbjct: 280 AAKNLQE----------AEEW---------YKSKFADLSEAANRNNDALRQAKQESTEYR 320 Query: 377 MTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQ 436 ++S+ + LK L+ + R + A + + + + D IQ +++ Sbjct: 321 RQVQSLTCEVD----ALKGTNESLERQMREMEENFAVEAANYQ--DTIGRLQDEIQNMKE 374 Query: 437 RLRDAEDTLQSLVHIKATLEYDLA 460 + Q L+++K L+ ++A Sbjct: 375 EMARHLREYQDLLNVKMALDIEIA 398 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 46.6 bits (109), Expect = 5e-05 Identities = 77/367 (20%), Positives = 149/367 (40%), Gaps = 38/367 (10%) Query: 133 QQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPL 192 Q+ + D Q ++VN + KS++ +++++ ++ LER + E L Sbjct: 1001 QEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDL 1060 Query: 193 QVARECLFHRE---KRMGIDLVHDEVE-AQLLTEVDTILCCQERMKLHLDKAIAQLAANR 248 ++A+E + E +++ L + E QL ++V+ ++ + L K I +L + Sbjct: 1061 KLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED----EQTLGLQFQKKIKEL---Q 1113 Query: 249 ASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNI 308 A ELE+++ ++ +K SD Y R +E + + E T I Sbjct: 1114 ARIEELEEEIEAERATRAKTEK-----QRSD---YARELEELSERL---EEAGGVTSTQI 1162 Query: 309 LRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKT 368 ++ A KLR D+E + M K + + E D +++ L K Sbjct: 1163 ELNKKREAEFLKLRRDLEE-ATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1221 Query: 369 LQEI-FQTEMTIESIKKAIKDKTAFLKVAQTRLDE--RTRRPNIELCRDMAQL-----RL 420 E + + S++ K K K+ +T D+ R N E+ R +++L RL Sbjct: 1222 KSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRL 1281 Query: 421 VNEVHEVDDTIQ----TLQQRLRDAEDTLQSLVHIKATLEYDLAVK---ANSLYIDQEKC 473 E E+ ++ + Q R + Q +K LE + K A++L + C Sbjct: 1282 QTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDC 1341 Query: 474 MSMRKSY 480 +R+ Y Sbjct: 1342 DLLREQY 1348 Score = 43.1 bits (100), Expect = 6e-04 Identities = 70/360 (19%), Positives = 153/360 (42%), Gaps = 50/360 (13%) Query: 128 IQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALME 187 ++++ + R T+A T + + ++ E+ L+E G T+ ++ K+ E ++ Sbjct: 1119 LEEEIEAERATRAKTEKQRSDYAREL----EELSERLEEAGGVTSTQIELNKKREAEFLK 1174 Query: 188 TEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAAN 247 L+ A L H + H + A+L ++D + +R+K L+K Sbjct: 1175 LRRDLEEAT--LQHEAMVAALRKKHADSVAELGEQIDNL----QRVKQKLEK-------- 1220 Query: 248 RASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDN 307 S+ +LE IDD + + S +E++ T+ S A+ ++ Sbjct: 1221 EKSEFKLE-----------IDDLSSSMESVSKSKA---NLEKICRTLEDQLSEARGKNEE 1266 Query: 308 ILRSQSERAAS-AKLRDDIENLL--VVTANEMWNQFNKVNLSFTNRIAETA---DAKNKI 361 I RS SE ++L+ + L + + +Q ++ +FT + E + +NK Sbjct: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326 Query: 362 QTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELC--RDMAQLR 419 + LA LQ + + +++ +++ + + L + N E+ R + Sbjct: 1327 KNALAHALQS---SRHDCDLLREQYEEE----QEGKAELQRALSKANSEVAQWRTKYETD 1379 Query: 420 LVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLE---YDLAVKANSLYIDQEKCMSM 476 + E+++ + L QRL+D+E+ ++++ A+LE L + L +D E+ S+ Sbjct: 1380 AIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSL 1439 Score = 40.4 bits (93), Expect = 0.004 Identities = 76/405 (18%), Positives = 167/405 (41%), Gaps = 44/405 (10%) Query: 73 QRVSENTMLPFVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKY 132 Q + +++ +S FT+ T ++ R + N H + R D L++++Y Sbjct: 1291 QLEEKESIVSQLSRSKQAFTQQT-EELKRQLEEENKAKNALAHALQSSRHDCD-LLREQY 1348 Query: 133 QQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPL 192 ++ ++ +A+ + L + +++ W+++ +E D I T L + KK+L + L ++E + Sbjct: 1349 EEEQEGKAELQRALSKANSEVAQWRTK--YETD-AIQRTEELEEAKKKLAQRLQDSEEQV 1405 Query: 193 QVARECLFHREKRMGIDLVHDEVEAQLLTEVD---TILCCQERMKLHLDKAIAQLAAN-R 248 + EK + EVE L+ +V+ ++ ++ + + DK +A+ Sbjct: 1406 EAVNAKCASLEKTK--QRLQGEVE-DLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCE 1462 Query: 249 ASQHELEKDLSDKQTAYRIDDKCHHLRNT-SDGVGYFRGVER---------VDATVSVPE 298 SQ ELE L + ++ + + L+N + + V+R D T + E Sbjct: 1463 ESQAELEASLKESRS---LSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAE 1519 Query: 299 SWAKFTDDNILRSQSE----------RAASAKLRDDIENLLVVTANEMWNQFNKVNLSFT 348 + + R Q E A A L + +L + + +V Sbjct: 1520 NGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL-----ELTQVKSEID 1574 Query: 349 NRIAETADAKNKIQTHLAKTLQEIFQT-EMTIESIKKAIKDKTAFLKVAQTRLDERTRRP 407 +IAE + +++ + +T++ + + + S +AI+ K ++ ++ + Sbjct: 1575 RKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKK-MEGDLNEIEIQLSHA 1633 Query: 408 NIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIK 452 N + + LR V ++ DT L LR ED + L ++ Sbjct: 1634 NRQAAETLKHLRSVQ--GQLKDTQLHLDDALRGQEDLKEQLAIVE 1676 Score = 29.6 bits (65), Expect = 6.5 Identities = 52/266 (19%), Positives = 103/266 (38%), Gaps = 38/266 (14%) Query: 114 RHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNA 173 R N + V+ R ++ ++ RK + ERV + + +IH Sbjct: 1678 RANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH----------- 1726 Query: 174 LTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERM 233 KK+LE LM+ ++ ++ A + E++ + + A+ L + ERM Sbjct: 1727 ---TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1783 Query: 234 KLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDAT 293 K +L++ + L +R + E K+ +++ + L +G E+ T Sbjct: 1784 KKNLEQTVKDL-QHRLDEAEQLALKGGKKQIQKLETRIRELEFELEG-------EQKKNT 1835 Query: 294 VSVP--ESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRI 351 SV + + + +S+ +R +L+D ++ L +V + R Sbjct: 1836 ESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKL-------------QVKVKSYKRQ 1882 Query: 352 AETADAK-NKIQTHLAKTLQEIFQTE 376 AE AD + N T K E+ + E Sbjct: 1883 AEEADEQANAHLTKFRKAQHELEEAE 1908 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 46.6 bits (109), Expect = 5e-05 Identities = 72/379 (18%), Positives = 156/379 (41%), Gaps = 52/379 (13%) Query: 126 RLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERAL 185 + +Q+ +QQT D Q ++VN + K ++ ++D++ G ++ LERA Sbjct: 1003 KALQEAHQQT----LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058 Query: 186 METEAPLQVARECLF---HREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIA 242 + E L++A+E + + ++++ L E E ++ + + + ++ + + L K I Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFE---ISNLQSKIEDEQALGIQLQKKIK 1115 Query: 243 QLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAK 302 +L +A ELE+++ ++ + +K SD R +E + + E Sbjct: 1116 EL---QARIEELEEEIEAERASRAKAEK-----QRSD---LSRELEEISERL---EEAGG 1161 Query: 303 FTDDNILRSQSERAASAKLRDDIENLLV---VTANEMWNQFNKVNLSFTNRIAETADAKN 359 T I ++ A K+R D+E + TA + + +I K Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1221 Query: 360 KIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLR 419 K++ ++ EI +E++ KA + + + +L E ++ Q R Sbjct: 1222 KLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK-------SKEEEQQR 1274 Query: 420 LVNEV---------------HEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVK-- 462 L+N++ ++D+ + Q R + Q + +K LE ++ K Sbjct: 1275 LINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334 Query: 463 -ANSLYIDQEKCMSMRKSY 480 A++L + C +R+ Y Sbjct: 1335 LAHALQSSRHDCDLLREQY 1353 Score = 43.5 bits (101), Expect = 4e-04 Identities = 84/397 (21%), Positives = 167/397 (42%), Gaps = 70/397 (17%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTR---KTQADTTQNLGERVNDIG 154 +W + + E S+ + L + + I++ Y+++ +T +NL + ++D+ Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFK-IKNAYEESLDQLETLKRENKNLQQEISDL- 1518 Query: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE-KRMGIDLVHD 213 +E I E + I E L +KK++E+ E +A L+ A L H E K + I L + Sbjct: 1519 ---TEQIAEGGKRIHE---LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELN 1572 Query: 214 EVEAQLLTEVDTILCCQERMKLHLDKAIAQLAAN-----RASQHELEKDLSDKQTAYRID 268 +V++++ +R D+ I QL N + Q L+ ++ + A R+ Sbjct: 1573 QVKSEV-----------DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621 Query: 269 DKC------------HHLRNTSDGVGYFRGVERV--DATVSVPESWAKFTDDNILRSQSE 314 K H R ++ + +R + + D + + ++ D + E Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681 Query: 315 RAASAKLRDDIENLLV----------VTANEMWNQFNKVNLSFTNRIAETADAKNKIQTH 364 R A+ L+ +IE L + E+ + +V L T + K K++T Sbjct: 1682 RRANL-LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN-TSLINTKKKLETD 1739 Query: 365 LAK---TLQEIFQTEMTI-ESIKKAIKDKTAFLKVAQTRLD-----ERTRRPNIELCRDM 415 +++ +++I Q E KKAI D + + D ER ++ + +D+ Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799 Query: 416 AQLRLVNEVHEV-----DDTIQTLQQRLRDAEDTLQS 447 QLRL +E ++ IQ L+ R+R+ E ++S Sbjct: 1800 -QLRL-DEAEQLALKGGKKQIQKLEARVRELEGEVES 1834 Score = 35.8 bits (81), Expect = 0.091 Identities = 82/421 (19%), Positives = 163/421 (38%), Gaps = 83/421 (19%) Query: 111 NTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGE 170 N H + R D L++++Y++ ++++A+ + L + ++ W+++ +E D I Sbjct: 1333 NALAHALQSSRHDCD-LLREQYEEEQESKAELQRALSKANTEVAQWRTK--YETD-AIQR 1388 Query: 171 TNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQ 230 T L + KK+L + L E ++ EK + +EVE +L T C Sbjct: 1389 TEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK--QRLQNEVEDLMLDVERTNAACA 1446 Query: 231 --ERMKLHLDKAI-----------AQLAANRASQHELEKDLSDKQTAYRID-DKCHHLRN 276 ++ + + DK + A+L A++ L +L + AY D+ L+ Sbjct: 1447 ALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR 1506 Query: 277 TSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSER----------AASAKLRDDIE 326 + + E D T + E + + ++ Q E+ A A L + Sbjct: 1507 ENKNLQQ----EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEG 1562 Query: 327 NLL----------------VVTANEMWNQFNKVNLSFTNRIAETADA-----------KN 359 +L + +E +Q + ++ + T DA K Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622 Query: 360 KIQTHLAK-TLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTR-----RPNIELCR 413 K++ L + +Q M E+++ ++ LK Q LD+ R + + + Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRN-YRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681 Query: 414 DMAQLRLVNEVHEVDDTIQ-------TLQQRLRDAEDTLQ-------SLVHIKATLEYDL 459 A L L E+ E+ T++ +Q L DA + +Q SL++ K LE D+ Sbjct: 1682 RRANL-LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 Query: 460 A 460 + Sbjct: 1741 S 1741 Score = 33.1 bits (74), Expect = 0.59 Identities = 66/347 (19%), Positives = 144/347 (41%), Gaps = 50/347 (14%) Query: 151 NDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDL 210 +D+ EI L+E G T+A ++ K+ E + L+ A L H + Sbjct: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT--LQHEATAATLRK 1200 Query: 211 VHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDK 270 H + A+L ++D + +R+K L+K +++ + E++ S+ +T + Sbjct: 1201 KHADSVAELGEQIDNL----QRVKQKLEKEKSEM------KMEIDDLASNVETVSKAKGN 1250 Query: 271 CHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNIL---RSQSERAASAKLRDDIEN 327 + T + +++ S E + +D R Q+E ++ D+ E Sbjct: 1251 LEKMCRTLE--------DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEA 1302 Query: 328 LLVVTANEMWNQFNKVNLSFTNRIAETA---DAKNKIQTHLAKTLQEIFQTEMTIESIKK 384 L+ +Q ++ +FT +I E + + K + LA LQ + + +++ Sbjct: 1303 LV--------SQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQS---SRHDCDLLRE 1351 Query: 385 AIKDKTAFLKVAQTRLDERTRRPNIELC--RDMAQLRLVNEVHEVDDTIQTLQQRLRDAE 442 +++ + ++ L + N E+ R + + E+++ + L QRL+ AE Sbjct: 1352 QYEEE----QESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407 Query: 443 DTLQSLVHIKATLE---YDLAVKANSLYIDQEK----CMSMRKSYPN 482 + ++++ A+LE L + L +D E+ C ++ K N Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRN 1454 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 46.6 bits (109), Expect = 5e-05 Identities = 72/379 (18%), Positives = 156/379 (41%), Gaps = 52/379 (13%) Query: 126 RLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERAL 185 + +Q+ +QQT D Q ++VN + K ++ ++D++ G ++ LERA Sbjct: 1003 KALQEAHQQT----LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058 Query: 186 METEAPLQVARECLF---HREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIA 242 + E L++A+E + + ++++ L E E ++ + + + ++ + + L K I Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFE---ISNLQSKIEDEQALGIQLQKKIK 1115 Query: 243 QLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAK 302 +L +A ELE+++ ++ + +K SD R +E + + E Sbjct: 1116 EL---QARIEELEEEIEAERASRAKAEK-----QRSD---LSRELEEISERL---EEAGG 1161 Query: 303 FTDDNILRSQSERAASAKLRDDIENLLV---VTANEMWNQFNKVNLSFTNRIAETADAKN 359 T I ++ A K+R D+E + TA + + +I K Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1221 Query: 360 KIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLR 419 K++ ++ EI +E++ KA + + + +L E ++ Q R Sbjct: 1222 KLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK-------SKEEEQQR 1274 Query: 420 LVNEV---------------HEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVK-- 462 L+N++ ++D+ + Q R + Q + +K LE ++ K Sbjct: 1275 LINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNA 1334 Query: 463 -ANSLYIDQEKCMSMRKSY 480 A++L + C +R+ Y Sbjct: 1335 LAHALQSSRHDCDLLREQY 1353 Score = 43.5 bits (101), Expect = 4e-04 Identities = 84/397 (21%), Positives = 167/397 (42%), Gaps = 70/397 (17%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTR---KTQADTTQNLGERVNDIG 154 +W + + E S+ + L + + I++ Y+++ +T +NL + ++D+ Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFK-IKNAYEESLDQLETLKRENKNLQQEISDL- 1518 Query: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE-KRMGIDLVHD 213 +E I E + I E L +KK++E+ E +A L+ A L H E K + I L + Sbjct: 1519 ---TEQIAEGGKRIHE---LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELN 1572 Query: 214 EVEAQLLTEVDTILCCQERMKLHLDKAIAQLAAN-----RASQHELEKDLSDKQTAYRID 268 +V++++ +R D+ I QL N + Q L+ ++ + A R+ Sbjct: 1573 QVKSEV-----------DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1621 Query: 269 DKC------------HHLRNTSDGVGYFRGVERV--DATVSVPESWAKFTDDNILRSQSE 314 K H R ++ + +R + + D + + ++ D + E Sbjct: 1622 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681 Query: 315 RAASAKLRDDIENLLV----------VTANEMWNQFNKVNLSFTNRIAETADAKNKIQTH 364 R A+ L+ +IE L + E+ + +V L T + K K++T Sbjct: 1682 RRANL-LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN-TSLINTKKKLETD 1739 Query: 365 LAK---TLQEIFQTEMTI-ESIKKAIKDKTAFLKVAQTRLD-----ERTRRPNIELCRDM 415 +++ +++I Q E KKAI D + + D ER ++ + +D+ Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799 Query: 416 AQLRLVNEVHEV-----DDTIQTLQQRLRDAEDTLQS 447 QLRL +E ++ IQ L+ R+R+ E ++S Sbjct: 1800 -QLRL-DEAEQLALKGGKKQIQKLEARVRELEGEVES 1834 Score = 35.8 bits (81), Expect = 0.091 Identities = 82/421 (19%), Positives = 163/421 (38%), Gaps = 83/421 (19%) Query: 111 NTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGE 170 N H + R D L++++Y++ ++++A+ + L + ++ W+++ +E D I Sbjct: 1333 NALAHALQSSRHDCD-LLREQYEEEQESKAELQRALSKANTEVAQWRTK--YETD-AIQR 1388 Query: 171 TNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQ 230 T L + KK+L + L E ++ EK + +EVE +L T C Sbjct: 1389 TEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK--QRLQNEVEDLMLDVERTNAACA 1446 Query: 231 --ERMKLHLDKAI-----------AQLAANRASQHELEKDLSDKQTAYRID-DKCHHLRN 276 ++ + + DK + A+L A++ L +L + AY D+ L+ Sbjct: 1447 ALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR 1506 Query: 277 TSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSER----------AASAKLRDDIE 326 + + E D T + E + + ++ Q E+ A A L + Sbjct: 1507 ENKNLQQ----EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEG 1562 Query: 327 NLL----------------VVTANEMWNQFNKVNLSFTNRIAETADA-----------KN 359 +L + +E +Q + ++ + T DA K Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622 Query: 360 KIQTHLAK-TLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTR-----RPNIELCR 413 K++ L + +Q M E+++ ++ LK Q LD+ R + + + Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRN-YRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681 Query: 414 DMAQLRLVNEVHEVDDTIQ-------TLQQRLRDAEDTLQ-------SLVHIKATLEYDL 459 A L L E+ E+ T++ +Q L DA + +Q SL++ K LE D+ Sbjct: 1682 RRANL-LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740 Query: 460 A 460 + Sbjct: 1741 S 1741 Score = 33.1 bits (74), Expect = 0.59 Identities = 66/347 (19%), Positives = 144/347 (41%), Gaps = 50/347 (14%) Query: 151 NDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDL 210 +D+ EI L+E G T+A ++ K+ E + L+ A L H + Sbjct: 1143 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT--LQHEATAATLRK 1200 Query: 211 VHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDK 270 H + A+L ++D + +R+K L+K +++ + E++ S+ +T + Sbjct: 1201 KHADSVAELGEQIDNL----QRVKQKLEKEKSEM------KMEIDDLASNVETVSKAKGN 1250 Query: 271 CHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNIL---RSQSERAASAKLRDDIEN 327 + T + +++ S E + +D R Q+E ++ D+ E Sbjct: 1251 LEKMCRTLE--------DQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEA 1302 Query: 328 LLVVTANEMWNQFNKVNLSFTNRIAETA---DAKNKIQTHLAKTLQEIFQTEMTIESIKK 384 L+ +Q ++ +FT +I E + + K + LA LQ + + +++ Sbjct: 1303 LV--------SQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQS---SRHDCDLLRE 1351 Query: 385 AIKDKTAFLKVAQTRLDERTRRPNIELC--RDMAQLRLVNEVHEVDDTIQTLQQRLRDAE 442 +++ + ++ L + N E+ R + + E+++ + L QRL+ AE Sbjct: 1352 QYEEE----QESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407 Query: 443 DTLQSLVHIKATLE---YDLAVKANSLYIDQEK----CMSMRKSYPN 482 + ++++ A+LE L + L +D E+ C ++ K N Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRN 1454 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 46.2 bits (108), Expect = 7e-05 Identities = 74/371 (19%), Positives = 159/371 (42%), Gaps = 36/371 (9%) Query: 126 RLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERAL 185 + +Q+ +QQT D Q ++VN + K ++ ++D++ G ++ LERA Sbjct: 1001 KALQEAHQQT----LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056 Query: 186 METEAPLQVARECLFHRE---KRMGIDLVHDEVE---AQLLTEVDTILCCQERMKL---- 235 + E L++A+E E +++ L E E Q E + L Q + K+ Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116 Query: 236 -HLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATV 294 +++ ++ A RAS+ + EK SD + +++ L +++ Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSD--LSRELEEISERLEEAGGATS-----AQIEMNK 1169 Query: 295 SVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAET 354 + K D + A +A LR + + E+ Q + + E Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKHAD----SVAELGEQIDNLQRVKQKLEKEK 1225 Query: 355 ADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRD 414 ++ K +I LA ++ + + + +E + +A++D+ + +K T+ +E+ R N +L Sbjct: 1226 SEMKMEID-DLASNMETVSKAKGNLEKMCRALEDQLSEIK---TKEEEQQRLIN-DLTAQ 1280 Query: 415 MAQLRLVNEVH--EVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVK---ANSLYID 469 A+L+ + + ++D+ + Q R + Q + +K LE ++ K A++L Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340 Query: 470 QEKCMSMRKSY 480 + C +R+ Y Sbjct: 1341 RHDCDLLREQY 1351 Score = 42.4 bits (98), Expect = 0.001 Identities = 80/398 (20%), Positives = 164/398 (41%), Gaps = 72/398 (18%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTR---KTQADTTQNLGERVNDIG 154 +W + + E S+ S L + + I++ Y+++ +T +NL + ++D+ Sbjct: 1459 EWKQKCEETHAELEASQKESRSLSTELFK-IKNAYEESLDQLETLKRENKNLQQEISDL- 1516 Query: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE-KRMGIDLVHD 213 +E I E + I E L +KK++E+ E +A L+ A L H E K + I L + Sbjct: 1517 ---TEQIAEGGKRIHE---LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELN 1570 Query: 214 EVEAQLLTEVDTILCCQERMKLHLDKAIAQLAAN-----RASQHELEKDLSDKQTAYRID 268 +V++++ +R D+ I Q+ N + Q L+ ++ + A R+ Sbjct: 1571 QVKSEV-----------DRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619 Query: 269 DKC------------HHLRNTSDGVGYFRGVERV--DATVSVPESWAKFTDDNILRSQSE 314 K H R ++ + +R + + D + + ++ D + E Sbjct: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679 Query: 315 RAASAKLRDDIENLLV----------VTANEMWNQFNKVNLSFTNRIAETADAKNKIQTH 364 R A+ L+ +IE L + E+ + +V L T + K K++T Sbjct: 1680 RRANL-LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN-TSLINTKKKLETD 1737 Query: 365 LAK---TLQEIFQTEMTI-ESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRL 420 +++ +++I Q E KKAI D +A+ E+ ++E + + + Sbjct: 1738 ISQIQGEMEDIIQEARNAEEKAKKAITDAA---MMAEELKKEQDTSAHLERMKKNLEQTV 1794 Query: 421 VNEVHEVDDT-----------IQTLQQRLRDAEDTLQS 447 + H +D+ IQ L+ R+R+ E ++S Sbjct: 1795 KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVES 1832 Score = 37.7 bits (86), Expect = 0.024 Identities = 81/420 (19%), Positives = 165/420 (39%), Gaps = 90/420 (21%) Query: 112 TSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGET 171 +SRH+ + LR ++Y++ ++ +A+ + + + +++ W+++ +E D I T Sbjct: 1339 SSRHDCDLLR--------EQYEEEQEAKAELQRAMSKANSEVAQWRTK--YETD-AIQRT 1387 Query: 172 NALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQ- 230 L + KK+L + L + E ++ EK + +EVE ++ T C Sbjct: 1388 EELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK--QRLQNEVEDLMIDVERTNAACAA 1445 Query: 231 -ERMKLHLDKAI-----------AQLAANRASQHELEKDLSDKQTAYRID-DKCHHLRNT 277 ++ + + DK + A+L A++ L +L + AY D+ L+ Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRE 1505 Query: 278 SDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSER----------AASAKLRDDIEN 327 + + E D T + E + + ++ Q E+ A A L + Sbjct: 1506 NKNLQQ----EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGK 1561 Query: 328 LL----------------VVTANEMWNQFNKVNLSFTNRIAETADA-----------KNK 360 +L + +E +Q + ++ + T DA K K Sbjct: 1562 ILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1621 Query: 361 IQTHLAK-TLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTR-----RPNIELCRD 414 ++ L + +Q M E+++ ++ A LK Q LD+ R + + + Sbjct: 1622 MEGDLNEMEIQLNHANRMAAEALRN-YRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER 1680 Query: 415 MAQLRLVNEVHEVDDTIQ-------TLQQRLRDAEDTLQ-------SLVHIKATLEYDLA 460 A L L E+ E+ T++ +Q L DA + +Q SL++ K LE D++ Sbjct: 1681 RANL-LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739 Score = 36.6 bits (83), Expect = 0.053 Identities = 70/352 (19%), Positives = 144/352 (40%), Gaps = 60/352 (17%) Query: 151 NDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDL 210 +D+ EI L+E G T+A ++ K+ E + L+ A L H + Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT--LQHEATAATLRK 1198 Query: 211 VHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDK 270 H + A+L ++D + +R+K +LEK+ S+ + IDD Sbjct: 1199 KHADSVAELGEQIDNL----QRVK-----------------QKLEKEKSEMKM--EIDDL 1235 Query: 271 CHHLRNTSDGVGYFRGV-----ERVDATVSVPESWAKFTDD---NILRSQSERAASAKLR 322 ++ S G + +++ + E + +D R Q+E ++ Sbjct: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL 1295 Query: 323 DDIENLLVVTANEMWNQFNKVNLSFTNRIAETA---DAKNKIQTHLAKTLQEIFQTEMTI 379 D+ + L+ +Q ++ +FT +I E + + K ++ LA LQ + Sbjct: 1296 DEKDTLV--------SQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQS---SRHDC 1344 Query: 380 ESIKKAIKDKTAFLKVAQTRLDERTRRPNIELC--RDMAQLRLVNEVHEVDDTIQTLQQR 437 + +++ +++ + A+ L + N E+ R + + E+++ + L QR Sbjct: 1345 DLLREQYEEE----QEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400 Query: 438 LRDAEDTLQSLVHIKATLE---YDLAVKANSLYIDQEK----CMSMRKSYPN 482 L+DAE+ ++++ A+LE L + L ID E+ C ++ K N Sbjct: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRN 1452 Score = 34.7 bits (78), Expect = 0.20 Identities = 76/366 (20%), Positives = 146/366 (39%), Gaps = 61/366 (16%) Query: 136 RKTQADTTQNLGERVNDIGFWK-------SEIIHELDEMIGETNALTDVKKRLE---RAL 185 RK AD+ LGE+++++ K SE+ E+D++ ++ K LE RAL Sbjct: 1197 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRAL 1256 Query: 186 METEAPLQVARECLFHREKRMGIDLVHDEVEAQL--------LTEVDTILCCQERMKLHL 237 + + ++ E ++R+ DL Q L E DT++ R K Sbjct: 1257 EDQLSEIKTKEE----EQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAF 1312 Query: 238 DKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRG-VERV--DATV 294 + I +L + + + L+ + R D C LR + + ++R A Sbjct: 1313 TQQIEELKRQLEEEIKAKSALAHALQSSRHD--CDLLREQYEEEQEAKAELQRAMSKANS 1370 Query: 295 SVPESWAKFTDDNILRSQSERAASAKLRDDIENL-------------LVVTANEMWNQFN 341 V + K+ D I R++ A KL +++ L T + N+ Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE 1430 Query: 342 --KVNLSFTNRIAETADAKNK-IQTHLAKTLQEIFQTEMTIESIKKAIKD-KTAFLKVA- 396 +++ TN D K + LA+ Q+ +T +E+ +K + T K+ Sbjct: 1431 DLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKN 1490 Query: 397 --QTRLD--ERTRRPNIELCRDMAQL--------RLVNEVHEVDDTIQ----TLQQRLRD 440 + LD E +R N L ++++ L + ++E+ ++ ++ LQ L + Sbjct: 1491 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEE 1550 Query: 441 AEDTLQ 446 AE +L+ Sbjct: 1551 AEASLE 1556 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 46.2 bits (108), Expect = 7e-05 Identities = 71/365 (19%), Positives = 151/365 (41%), Gaps = 34/365 (9%) Query: 133 QQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPL 192 Q+T + D Q ++VN + K+++ ++D++ G ++ LERA + E L Sbjct: 1003 QETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062 Query: 193 QVARECLFHRE------------KRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKA 240 ++A+E E K I + ++E + E+ +E ++ +++ Sbjct: 1063 KLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKE-LQARIEEL 1121 Query: 241 IAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESW 300 ++ A RAS+ + EK SD + +++ L +V+ + Sbjct: 1122 GEEIEAERASRAKAEKQRSD--LSRELEEISERLEEAGGATS-----AQVELNKKREAEF 1174 Query: 301 AKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNK 360 K D + A A LR + + E+ Q + NL + E ++ K Sbjct: 1175 QKLRRDLEEATLQHEAMVAALRKKHADSMA----ELGEQID--NLQRVKQKLEKEKSELK 1228 Query: 361 IQT-HLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPN-IELCRDMAQL 418 ++T L+ + I + + +E + ++++D+ + LK T+ +E+ R N + R Q Sbjct: 1229 METDDLSSNAEAISKAKGNLEKMCRSLEDQVSELK---TKEEEQQRLINDLTAQRARLQT 1285 Query: 419 RLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVK---ANSLYIDQEKCMS 475 ++D+ + Q R + + Q + +K LE + K A++L + C Sbjct: 1286 EAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDL 1345 Query: 476 MRKSY 480 +R+ Y Sbjct: 1346 LREQY 1350 Score = 45.4 bits (106), Expect = 1e-04 Identities = 72/375 (19%), Positives = 149/375 (39%), Gaps = 56/375 (14%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTR---KTQADTTQNLGERVNDIG 154 +W + E S+ S L + + +++ Y+++ +T +NL + ++D+ Sbjct: 1458 EWKQKYEETQAELEASQKESRSLSTELFK-VKNVYEESLDQLETLRRENKNLQQEISDL- 1515 Query: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE-KRMGIDLVHD 213 +E I E + I E L +KK++E+ E +A L+ A L H E K + I L + Sbjct: 1516 ---TEQIAEGGKQIHE---LEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELN 1569 Query: 214 EVEAQLLTEVDTILCCQERMKLHLDKAIAQLAAN-----RASQHELEKDLSDKQTAYRID 268 +V++++ +R D+ I QL N Q L+ ++ + A R+ Sbjct: 1570 QVKSEV-----------DRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVK 1618 Query: 269 DKC------------HHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERA 316 K H R ++ + +R + + + E+ D+ LR Q + Sbjct: 1619 KKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI-----LKETQLHL--DDALRGQEDLK 1671 Query: 317 ASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQ-THLAKTLQEIFQT 375 + + NLL E+W + S E DA ++Q H T + T Sbjct: 1672 EQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNT--SLINT 1729 Query: 376 EMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQ 435 + +E+ ++ + + +E+ ++ + + E+ + DT L+ Sbjct: 1730 KKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAA------MMAEELKKEQDTSAHLE 1783 Query: 436 QRLRDAEDTLQSLVH 450 + ++ E T++ L H Sbjct: 1784 RMKKNLEQTVKDLQH 1798 Score = 38.9 bits (89), Expect = 0.011 Identities = 62/317 (19%), Positives = 126/317 (39%), Gaps = 45/317 (14%) Query: 104 LTNYQESNTSRHNSEKLRVDTSR----LIQDKYQQTRKTQADTTQNLGERVNDIGFWKSE 159 L + E T N+ + +SR L++++Y++ ++ +A+ + L + +++ W+++ Sbjct: 1318 LKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1377 Query: 160 IIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQL 219 +E D I T L + KK+L + L E E ++ EK + +EVE + Sbjct: 1378 --YETD-AIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTK--QRLQNEVEDLM 1432 Query: 220 LTEVDTILCCQ--ERMKLHLDKAI-----------AQLAANRASQHELEKDLSDKQTAYR 266 L + C ++ + + DK + A+L A++ L +L + Y Sbjct: 1433 LDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYE 1492 Query: 267 ID-DKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSER---------- 315 D+ LR + + E D T + E + + ++ Q E+ Sbjct: 1493 ESLDQLETLRRENKNLQQ----EISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALE 1548 Query: 316 AASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIA---ETADAKNKIQTHLAKTLQEI 372 A A L + +L + + N+V +IA E D + T + +T+Q Sbjct: 1549 EAEASLEHEEGKILRIQL-----ELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQST 1603 Query: 373 FQTEMTIESIKKAIKDK 389 E+ + +K K Sbjct: 1604 LDAEIRSRNDALRVKKK 1620 Score = 35.8 bits (81), Expect = 0.091 Identities = 80/379 (21%), Positives = 151/379 (39%), Gaps = 73/379 (19%) Query: 136 RKTQADTTQNLGERVND-------IGFWKSEIIHELDEMIGETNALTDVKKRLE---RAL 185 RK AD+ LGE++++ + KSE+ E D++ A++ K LE R+L Sbjct: 1196 RKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL 1255 Query: 186 METEAPLQVARECLFHREKRMGIDLVHDEVEAQL--------LTEVDTILCCQERMKLHL 237 + + L+ E ++R+ DL Q L E D ++ R K Sbjct: 1256 EDQVSELKTKEE----EQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAS 1311 Query: 238 DKAIAQLAANRASQHELEKDLSDKQT-AYRIDDKCH-------HLRNTSDGVGYF-RGVE 288 + I +L +H+LE++ K A+ + H +G R + Sbjct: 1312 TQQIEEL------KHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1365 Query: 289 RVDATVSVPESW-AKFTDDNILRSQSERAASAKLRDDIENL-------------LVVTAN 334 + ++ V+ W K+ D I R++ A KL ++ L T Sbjct: 1366 KANSEVA---QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQ 1422 Query: 335 EMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTL----QEIFQTEMTIESIKKAIKDKT 390 + N+ + L A A A +K Q + K L Q+ +T+ +E+ +K + + Sbjct: 1423 RLQNEVEDLMLDVERSNAACA-ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLS 1481 Query: 391 AFL----KVAQTRLD--ERTRRPNIELCRDMAQLRLV-----NEVHEVDDTIQTLQQRLR 439 L V + LD E RR N L ++++ L ++HE++ + ++Q Sbjct: 1482 TELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKC 1541 Query: 440 DAEDTLQSLVHIKATLEYD 458 + + L+ +A+LE++ Sbjct: 1542 EIQAALE---EAEASLEHE 1557 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 45.1 bits (105), Expect = 1e-04 Identities = 75/371 (20%), Positives = 158/371 (42%), Gaps = 36/371 (9%) Query: 126 RLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERAL 185 + +Q+ +QQT D Q ++VN + K+++ ++D++ G + LERA Sbjct: 1001 KALQEAHQQT----LDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056 Query: 186 METEAPLQVARECLFHRE---KRMGIDLVHDEVEAQLL---TEVDTILCCQERMKL---- 235 + E L++A+E E +++ L E E L E + L Q + K+ Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116 Query: 236 -HLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATV 294 +++ ++ A RAS+ + EK SD + +++ L G +E Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSD--LSRELEEISERLEEA--GGATSAQIEMNKKRE 1172 Query: 295 SVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAET 354 + + + +++ L+ ++ AA K D + E+ Q + + E Sbjct: 1173 AEFQKMRRDLEESTLQHEATAAALRKKHAD-------SVAELGEQIDSLQRVKQKLEKEK 1225 Query: 355 ADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRD 414 ++ K +I LA ++ + + + E + + ++D+ + +K T+ +E+ R N EL Sbjct: 1226 SELKMEI-NDLASNMETVSKAKANFEKMCRTLEDQLSEIK---TKEEEQQRLIN-ELSAQ 1280 Query: 415 MAQLRLVNE--VHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVK---ANSLYID 469 A+L + ++D+ + Q R + Q + +K LE + K A++L Sbjct: 1281 KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSA 1340 Query: 470 QEKCMSMRKSY 480 + C +R+ Y Sbjct: 1341 RHDCDLLREQY 1351 Score = 40.8 bits (94), Expect = 0.003 Identities = 85/391 (21%), Positives = 162/391 (41%), Gaps = 58/391 (14%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTR---KTQADTTQNLGERVNDIG 154 +W + E S+ S L + + +++ Y+++ +T +NL + ++D+ Sbjct: 1459 EWKQKYEETQAELEASQKESRSLSTELFK-VKNAYEESLDHLETLKRENKNLQQEISDL- 1516 Query: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKR-----MGID 209 +E I E + I E L VKK+L+ E + L+ A L H E + + ++ Sbjct: 1517 ---TEQIAEGGKHIHE---LEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELN 1570 Query: 210 LVHDEVEAQLL---TEVDTI----LCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQ 262 V E++ ++ E+D + L E M+ LD I + ++E DL++ + Sbjct: 1571 QVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEME 1630 Query: 263 TAY-----RIDDKCHHLRNTSDGV---------GYFRGVERVDATVSVPESWAKFTDDNI 308 + + +LRNT G+ RG + + +++ E A + Sbjct: 1631 IQLNHANRQAAEALRNLRNT-QGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEV 1689 Query: 309 --LRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLA 366 LR+ ER + + E ++ A+E + N S N + ++IQ + Sbjct: 1690 EELRASLERTERGRKMAEQE---LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEME 1746 Query: 367 KTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLD-----ERTRRPNIELCRDMAQLRLV 421 +QE E E KKAI D + + D ER ++ + +D+ QLRL Sbjct: 1747 DIVQEARNAE---EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL-QLRL- 1801 Query: 422 NEVHEV-----DDTIQTLQQRLRDAEDTLQS 447 +E ++ IQ L+ R+R+ E ++S Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELESEVES 1832 Score = 38.1 bits (87), Expect = 0.018 Identities = 76/422 (18%), Positives = 167/422 (39%), Gaps = 85/422 (20%) Query: 111 NTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGE 170 +T H + R D L++++Y++ ++ +A+ + + + +++ W+++ +E D I Sbjct: 1331 STLAHALQSARHDCD-LLREQYEEEQEAKAELQRGMSKANSEVAQWRTK--YETD-AIQR 1386 Query: 171 TNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCC- 229 T L + KK+L + L + E ++ EK + +EVE ++ + C Sbjct: 1387 TEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTK--QRLQNEVEDLMIDVERSNAACI 1444 Query: 230 -QERMKLHLDKAI-----------AQLAANRASQHELEKDLSDKQTAYRIDDKCHHL--- 274 ++ + + DK + A+L A++ L +L + AY ++ HL Sbjct: 1445 ALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAY--EESLDHLETL 1502 Query: 275 ---------------RNTSDGVGYFRGVERV-----------DATVSVPESWAKFTDDNI 308 ++G + +E+V ++ E+ + + I Sbjct: 1503 KRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKI 1562 Query: 309 LRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADA----------- 357 LR Q E +++ +I+ + E+ +Q + +L + T DA Sbjct: 1563 LRIQLE---LNQVKSEIDRKIAEKDEEL-DQLKRNHLRVVESMQSTLDAEIRSRNDALRI 1618 Query: 358 KNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTR-----RPNIELC 412 K K++ L + ++ + +++ LK Q LD+ R + + + Sbjct: 1619 KKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMV 1678 Query: 413 RDMAQLRLVNEVHEVDDTIQ-------TLQQRLRDAEDTLQ-------SLVHIKATLEYD 458 A L + EV E+ +++ +Q L DA + +Q SL++ K LE D Sbjct: 1679 ERRANL-MQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737 Query: 459 LA 460 ++ Sbjct: 1738 IS 1739 Score = 37.4 bits (85), Expect = 0.031 Identities = 70/347 (20%), Positives = 143/347 (41%), Gaps = 50/347 (14%) Query: 151 NDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDL 210 +D+ EI L+E G T+A ++ K+ E + L+ L H + Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLE--ESTLQHEATAAALRK 1198 Query: 211 VHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDK 270 H + A+L ++D++ +R+K L+K ++L I+D Sbjct: 1199 KHADSVAELGEQIDSL----QRVKQKLEKEKSELKME-------------------INDL 1235 Query: 271 CHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAAS-AKLRDDIENLL 329 ++ S F E++ T+ S K ++ R +E +A A+L + Sbjct: 1236 ASNMETVSKAKANF---EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFS 1292 Query: 330 --VVTANEMWNQFNKVNLSFTNRIAETA---DAKNKIQTHLAKTLQEIFQTEMTIESIKK 384 + + M +Q ++ +FT +I E + + K ++ LA LQ + +++ Sbjct: 1293 RQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQS---ARHDCDLLRE 1349 Query: 385 AIKDKTAFLKVAQTRLDERTRRPNIELC--RDMAQLRLVNEVHEVDDTIQTLQQRLRDAE 442 +++ + A+ L + N E+ R + + E+++ + L QRL+DAE Sbjct: 1350 QYEEE----QEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1405 Query: 443 DTLQSLVHIKATLE---YDLAVKANSLYIDQEK----CMSMRKSYPN 482 + ++++ A+LE L + L ID E+ C+++ K N Sbjct: 1406 EHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRN 1452 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 44.7 bits (104), Expect = 2e-04 Identities = 78/369 (21%), Positives = 151/369 (40%), Gaps = 42/369 (11%) Query: 133 QQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPL 192 Q+ + D Q ++VN + K ++ ++D++ G V+ LERA + E L Sbjct: 1000 QEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1059 Query: 193 QVARECLFHRE---KRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRA 249 ++ +E + E +++ L + E L ++ + ++ + L K + +L +A Sbjct: 1060 KLTQESIMDLENDKQQLDERLKKKDFE---LNALNARIEDEQALGSQLQKKLKEL---QA 1113 Query: 250 SQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNIL 309 ELE++L ++TA K LR+ R +E + + E T I Sbjct: 1114 RIEELEEELEAERTARA---KVEKLRSDLS-----RELEEISERL---EEAGGATSVQIE 1162 Query: 310 RSQSERAASAKLRDDIENLLV---VTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLA 366 ++ A K+R D+E + TA + K + + E D +++ L Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAAL----RKKHADSVAELGEQIDNLQRVKQKLE 1218 Query: 367 KTLQEI-FQTEMTIESIKKAIKDKTAFLKVAQTRLD---------ERTRRPNIELCRDMA 416 K E + + ++++ IK K K+ +T D E T+R +L A Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRA 1278 Query: 417 QLRLVNE--VHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVK---ANSLYIDQE 471 +L+ N ++D+ + Q R Q L +K LE ++ K A++L + Sbjct: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338 Query: 472 KCMSMRKSY 480 C +R+ Y Sbjct: 1339 DCDLLREQY 1347 Score = 44.7 bits (104), Expect = 2e-04 Identities = 74/380 (19%), Positives = 161/380 (42%), Gaps = 40/380 (10%) Query: 97 DDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFW 156 +D R + N H + R D L++++Y++ + +A+ + L + +++ W Sbjct: 1313 EDLKRQLEEEVKAKNALAHALQSARHDCD-LLREQYEEETEAKAELQRVLSKANSEVAQW 1371 Query: 157 KSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVE 216 +++ +E D I T L + KK+L + L E E ++ EK + +E+E Sbjct: 1372 RTK--YETD-AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK--HRLQNEIE 1426 Query: 217 AQLLTEVD---TILCCQERMKLHLDKAIAQLAAN-RASQHELEKDLSDKQTAYRIDDKCH 272 L+ +V+ ++ + + DK +A+ SQ ELE S ++ A + + Sbjct: 1427 -DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE---SSQKEARSLSTELF 1482 Query: 273 HLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENL---L 329 L+N Y +E ++ + K + I + +S K ++E + L Sbjct: 1483 KLKN-----AYEESLEHLETF----KRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQL 1533 Query: 330 VVTANEMWNQFNKVNLSFTNRIAETADAK---NKIQTHLAKTLQEIFQTEMTIESIKKAI 386 E+ + + S + + A+ N+I+ + + L E E +++A Sbjct: 1534 EAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE------KDEEMEQAK 1587 Query: 387 KDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQ 446 ++ + QT LD TR N L + ++ +++E++ + + +A+ ++ Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEAL---RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644 Query: 447 SLVHI--KATLEYDLAVKAN 464 SL + ++ D AV+AN Sbjct: 1645 SLQSLLKDTQIQLDDAVRAN 1664 Score = 42.7 bits (99), Expect = 7e-04 Identities = 75/376 (19%), Positives = 146/376 (38%), Gaps = 58/376 (15%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRK---TQADTTQNLGERVNDIG 154 +W + + E +S+ + L + +L ++ Y+++ + T +NL E ++D+ Sbjct: 1455 EWKQKYEESQSELESSQKEARSLSTELFKL-KNAYEESLEHLETFKRENKNLQEEISDLT 1513 Query: 155 FW---KSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE-KRMGIDL 210 + IHEL++ V+K+LE ME ++ L+ A L H E K + L Sbjct: 1514 EQLGSSGKTIHELEK----------VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563 Query: 211 VHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANR-----ASQHELEKDLSDKQTAY 265 ++++A++ ER D+ + Q N + Q L+ + + A Sbjct: 1564 EFNQIKAEI-----------ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEAL 1612 Query: 266 RIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDI 325 R+ K N + +A V + D I + RA DD+ Sbjct: 1613 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-----NDDL 1667 Query: 326 -ENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKI-QTHLAKTLQEIFQTEMTIESIK 383 EN+ +V E N + L + E + K+ + L +T + + S+ Sbjct: 1668 KENIAIV---ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1724 Query: 384 KAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQ---------LRLVNEVHEVDDTIQTL 434 K A L QT ++E ++ CR+ + + E+ + DT L Sbjct: 1725 NQKKKMDADLSQLQTEVEEA-----VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1779 Query: 435 QQRLRDAEDTLQSLVH 450 ++ ++ E T++ L H Sbjct: 1780 ERMKKNMEQTIKDLQH 1795 Score = 32.0 bits (71), Expect = 1.3 Identities = 61/337 (18%), Positives = 137/337 (40%), Gaps = 54/337 (16%) Query: 151 NDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDL 210 +D+ EI L+E G T+ ++ K+ E + L+ A L H + Sbjct: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT--LQHEATAAALRK 1194 Query: 211 VHDEVEAQLLTEVDTILCCQERM-------KLHLDKAIAQLAANRASQHELEKDLSDKQT 263 H + A+L ++D + ++++ KL LD + + ++ LEK Sbjct: 1195 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK------M 1248 Query: 264 AYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRD 323 ++D+ + R+ ++ E + + AK Q+E ++ D Sbjct: 1249 CRTLEDQMNEHRSKAE--------ETQRSVNDLTSQRAKL--------QTENGELSRQLD 1292 Query: 324 DIENLLVVTANEMWNQFNKVNLSFTNRIAETA---DAKNKIQTHLAKTLQEIFQTEMTIE 380 + E L+ +Q + L++T ++ + + + K + LA LQ + Sbjct: 1293 EKEALI--------SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQS---ARHDCD 1341 Query: 381 SIKKAIKDKTAFLKVAQTRLDERTRRPNIELC--RDMAQLRLVNEVHEVDDTIQTLQQRL 438 +++ +++T A+ L + N E+ R + + E+++ + L QRL Sbjct: 1342 LLREQYEEETE----AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397 Query: 439 RDAEDTLQSLVHIKATLE---YDLAVKANSLYIDQEK 472 ++AE+ ++++ ++LE + L + L +D E+ Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 43.9 bits (102), Expect = 3e-04 Identities = 77/393 (19%), Positives = 162/393 (41%), Gaps = 52/393 (13%) Query: 109 ESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMI 168 E N S+ EK + +Q+ +QQT D Q ++VN + +++ + D++ Sbjct: 990 EENISKLTKEK------KSLQEAHQQT----LDDLQVEEDKVNGLIKINAKLEQQTDDLE 1039 Query: 169 GETNALTDVKKRLERALMETEAPLQVARECLFHRE---KRMGIDLVHDEVE-AQLLTEVD 224 G ++ LERA + E L++++E + E +++ L E E +QL ++D Sbjct: 1040 GSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKID 1099 Query: 225 TILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYF 284 ++ L K I +L +A ELE+++ + T +K SD Sbjct: 1100 D----EQVHSLQFQKKIKEL---QARIEELEEEIEAEHTLRAKIEK-----QRSD---LA 1144 Query: 285 RGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVV------------- 331 R +E + + E + T I ++ A K+R D+E + Sbjct: 1145 RELEEISERL---EEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQA 1201 Query: 332 -TANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKT 390 + E+ Q + + E ++ K +I +A ++ + +++ IE + ++D+ Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSELKMEID-DMASNIEALSKSKSNIERTCRTVEDQF 1260 Query: 391 AFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVH 450 + +K + + N++ R Q ++ H V++ + Q + + Q L Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELS--HRVEEKESLISQLTKSKQALTQQLEE 1318 Query: 451 IKATLEYDLAVK---ANSLYIDQEKCMSMRKSY 480 +K +E + K A++L + C +R+ Y Sbjct: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQY 1351 Score = 33.5 bits (75), Expect = 0.45 Identities = 62/346 (17%), Positives = 144/346 (41%), Gaps = 33/346 (9%) Query: 121 RVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKR 180 ++D ++ ++Q+ K + L E + +++I + ++ E L ++ +R Sbjct: 1097 KIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARE---LEEISER 1153 Query: 181 LERALMETEAPLQV--ARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLD 238 LE A T A +++ RE F + +R ++E L T +++ + Sbjct: 1154 LEEASGATSAQIEMNKKREAEFQKMRR--------DLEEATLQHEATAATLRKKQADSVA 1205 Query: 239 KAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPE 298 + Q+ + + +LEK+ S+ + IDD ++ S +ER TV Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSELKM--EIDDMASNIEALSKSKS---NIERTCRTVEDQF 1260 Query: 299 SWAKFTDDN---ILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETA 355 S K D+ ++ + + A + ++ + V + +Q K + T ++ E Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320 Query: 356 ---DAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELC 412 + + K + +A LQ + + +++ +++ + A+ L + N E+ Sbjct: 1321 RQMEEETKAKNAMAHALQS---SRHDCDLLREQYEEE----QEAKAELQRALSKANSEVA 1373 Query: 413 --RDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLE 456 R + + E+++ + L QRL++AE+ ++ A+LE Sbjct: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLE 1419 >gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] Length = 731 Score = 43.1 bits (100), Expect = 6e-04 Identities = 80/386 (20%), Positives = 153/386 (39%), Gaps = 50/386 (12%) Query: 108 QESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADT-TQNLGERVNDIGFWKSEIIHELDE 166 +E N +R EK D S+ D+ + + Q D T+ + + + + K + E D+ Sbjct: 257 EELNKARARVEKWNADHSK--SDRMTRGLRAQVDDLTEAVAAKDSQLAVLKVRL-QEADQ 313 Query: 167 MIGETN----ALTDVKKRL------------------ERALMETEAPLQVARECLFHREK 204 ++ AL K R+ + L E +A L+ +E + Sbjct: 314 LLSTRTEALEALQSEKSRIMQDQSEGNSLQNQALQTFQERLHEADATLKREQESYKQMQS 373 Query: 205 RMGIDLVHDEVEAQLLTEVDTILCCQERM----KLHLDKAIAQLAANRASQHELEKDLSD 260 L E+E Q L E T+ ER K +D+ Q+ + + +++L D Sbjct: 374 EFAARLNKVEMERQNLAEAITLA---ERKYSDEKKRVDELQQQVKLYKLNLESSKQELID 430 Query: 261 -KQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASA 319 KQ A RI L N+ F G++ +T S E + + R + ++ Sbjct: 431 YKQKATRILQSKEKLINSLKEGSGFEGLD--SSTASSMELEELRHEKEMQREEIQKLMGQ 488 Query: 320 --KLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTE- 376 +LR +++++ NE + ++ ++IA +K +++T L + QE E Sbjct: 489 IHQLRSELQDMEAQQVNEAESAREQLQ-DLHDQIAGQKASKQELETELERLKQEFHYIEE 547 Query: 377 ---MTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQT 433 T +++ IKD+ ++ + +L +T + +Q L N +H++ +T+ Sbjct: 548 DLYRTKNTLQSRIKDRDEEIQKLRNQLTNKT-------LSNSSQSELENRLHQLTETLIQ 600 Query: 434 LQQRLRDAEDTLQSLVHIKATLEYDL 459 Q L SLV LE + Sbjct: 601 KQTMLESLSTEKNSLVFQLERLEQQM 626 Score = 34.3 bits (77), Expect = 0.26 Identities = 42/201 (20%), Positives = 87/201 (43%), Gaps = 30/201 (14%) Query: 288 ERVDATVSVPESWAKFTDDNILRSQSE-RAASAKLRDDIENLLVVTANEMWNQFNKVNLS 346 E V + + P+ DD S R + LR+++++L N+ S Sbjct: 200 ENVSSNAACPDHTPTPNDDGKSHELSNLRLENQLLRNEVQSL------------NQEMAS 247 Query: 347 FTNRIAETADAKNKIQTHLAKTLQEIFQTE-MT------IESIKKAIKDKTAFLKVAQTR 399 R ET + NK + + K + +++ MT ++ + +A+ K + L V + R Sbjct: 248 LLQRSKETQEELNKARARVEKWNADHSKSDRMTRGLRAQVDDLTEAVAAKDSQLAVLKVR 307 Query: 400 LDER-----TRRPNIELCRDMAQLRLVNEVHE----VDDTIQTLQQRLRDAEDTLQSLVH 450 L E TR +E + + R++ + E + +QT Q+RL +A+ TL+ Sbjct: 308 LQEADQLLSTRTEALEALQS-EKSRIMQDQSEGNSLQNQALQTFQERLHEADATLKREQE 366 Query: 451 IKATLEYDLAVKANSLYIDQE 471 ++ + A + N + ++++ Sbjct: 367 SYKQMQSEFAARLNKVEMERQ 387 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 41.6 bits (96), Expect = 0.002 Identities = 75/376 (19%), Positives = 149/376 (39%), Gaps = 40/376 (10%) Query: 136 RKTQADTTQNLGERVND-------IGFWKSEIIHELDEMIGETNALTDVKKRLER----- 183 R+ QA+ LGE+V+ + KSE+ E+D++ LT K E+ Sbjct: 1242 RRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTY 1301 Query: 184 --ALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAI 241 L E + ++ + L + G ++LL E + ++ R K +++ Sbjct: 1302 EDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSL 1361 Query: 242 AQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRG-VERV--DATVSVPE 298 +L + + + L+ A R D C LR + + ++R+ A V + Sbjct: 1362 EELRRQLEEESKAKSALAHAVQALRHD--CDLLREQHEEEAEAQAELQRLLSKANAEVAQ 1419 Query: 299 SWAKFTDDNILRSQSERAASAKLRDDIENLL--VVTANEMWNQFNKVNLSF--------- 347 +K+ D I R++ A KL ++ V AN + K L Sbjct: 1420 WRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTL 1479 Query: 348 -TNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRR 406 R A A +K Q HL + L+E + E ++ +A + ++ L RL R Sbjct: 1480 ELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRL----RH 1535 Query: 407 PNIELCRDMAQLR-----LVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAV 461 + E + L+ L E+ ++ D + + +++ E T ++L K+ ++ L Sbjct: 1536 GHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEE 1595 Query: 462 KANSLYIDQEKCMSMR 477 +L +++ K + ++ Sbjct: 1596 AEGALELEETKTLRIQ 1611 Score = 41.2 bits (95), Expect = 0.002 Identities = 33/153 (21%), Positives = 75/153 (49%), Gaps = 9/153 (5%) Query: 115 HNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNAL 174 H + LR D L+++++++ + QA+ + L + ++ W+S+ +E D I T L Sbjct: 1380 HAVQALRHDCD-LLREQHEEEAEAQAELQRLLSKANAEVAQWRSK--YEAD-AIQRTEEL 1435 Query: 175 TDVKKRLERALMETEAPLQVAR-ECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERM 233 + KK+L L E E ++ A +C + ++ + ++V + L + ++ Sbjct: 1436 EEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLE-LERATSAAAALDKK 1494 Query: 234 KLHLDKAIAQLAANRASQHELEKDLSDKQTAYR 266 + HL++A+ + R + E++++L Q R Sbjct: 1495 QRHLERALEE---RRRQEEEMQRELEAAQRESR 1524 >gi|153791839 sodium channel associated protein 1 [Homo sapiens] Length = 688 Score = 41.6 bits (96), Expect = 0.002 Identities = 77/350 (22%), Positives = 137/350 (39%), Gaps = 49/350 (14%) Query: 109 ESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMI 168 E + EK++ SR +QD +T+K A+T + +++ + S + E E Sbjct: 353 EEKQKEEDIEKMKETVSRFVQDATIRTKKEVANTKKQCNIQISRLTEELSALQMECAEKQ 412 Query: 169 GETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILC 228 G+ + KK +E L + +RE R +E + + L E+ Sbjct: 413 GQIERVIKEKKAVEEELEK------------IYREGR------GNESDYRKLEEMHQRFL 454 Query: 229 CQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVE 288 ER K L + + A NR Q LE D S++ + Y+ + L+N + E Sbjct: 455 VSERSKDDLQLRLTR-AENRIKQ--LETDSSEEISRYQ--EMIQKLQNVLES-------E 502 Query: 289 RVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFT 348 R + + V E K +N + + E + K+ + + V + M ++F+ F Sbjct: 503 RENCGL-VSEQRLKLQQEN-KQLRKETESLRKIALEAQKKAKVKISTMEHEFSIKERGFE 560 Query: 349 NRIAETADA-KNKI--QTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTR 405 ++ E D+ +N I HL T Q+ K+ K T ++ L Sbjct: 561 VQLREMEDSNRNSIVELRHLLATQQK------AANRWKEETKKLTESAEIRINNLKSELS 614 Query: 406 RPNIELCRDMAQLRLVNE--------VHEVDDTIQTLQQRLRDAEDTLQS 447 R + ++QL + NE + E + LQ+RL AE+ S Sbjct: 615 RQKLHTQELLSQLEMANEKVAENEKLILEHQEKANRLQRRLSQAEERAAS 664 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 41.2 bits (95), Expect = 0.002 Identities = 81/391 (20%), Positives = 166/391 (42%), Gaps = 57/391 (14%) Query: 98 DWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFW- 156 +W + QE+ S NS LR D L+ D Y+Q R + + L E+ ND+ + Sbjct: 483 EWNPATKLLNQENIESELNS--LRADYDNLVLD-YEQLRTEKEEMELKLKEK-NDLDEFE 538 Query: 157 ----KSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVH 212 K++ E+ ++I E + L ++ K E + E L E L REK I + Sbjct: 539 ALERKTKKDQEM-QLIHEISNLKNLVKHAEVYNQDLENELSSKVELL--REKEDQIKKLQ 595 Query: 213 DEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCH 272 + +++Q L E +K+ L ++ + + ++++ L D +T +D K Sbjct: 596 EYIDSQKL----------ENIKMDLSYSLESIEDPK----QMKQTLFDAETV-ALDAKRE 640 Query: 273 HLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVT 332 S+ + ++ + T K +++I QS+ A K++ D+E L Sbjct: 641 SAFLRSENLELKEKMKELATTY-------KQMENDIQLYQSQLEAKKKMQVDLEKELQSA 693 Query: 333 ANEMWNQFNKV----------NLSFTNRIAETADAKNK-IQTHLAKTLQEIFQTEM---- 377 NE+ + + NL +I + NK ++ + A + I +E+ Sbjct: 694 FNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLP 753 Query: 378 -TIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLR-LVNEVHEVDDTIQTLQ 435 +E ++K I+DK+ L + + D+ E+ ++++ L+ E+ + D + T Q Sbjct: 754 SEVERLRKEIQDKSEELHIITSEKDKLFS----EVVHKESRVQGLLEEIGKTKDDLATTQ 809 Query: 436 QRLRDAEDTLQSL--VHIKATLEYDLAVKAN 464 + + Q+ +H+ +Y + ++ N Sbjct: 810 SNYKSTDQEFQNFKTLHMDFEQKYKMVLEEN 840 >gi|42794779 myosin 18A isoform b [Homo sapiens] Length = 2039 Score = 40.4 bits (93), Expect = 0.004 Identities = 91/423 (21%), Positives = 170/423 (40%), Gaps = 90/423 (21%) Query: 102 SNLTNYQESNTSRHNSEKLRVDTS-RLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEI 160 S LT+ E NT S+ L +T+ RL +K + +TQ D + E V ++ ++ + Sbjct: 1296 SELTD--ERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME-VMEMEVMEARL 1352 Query: 161 IH--ELDEMIGETNALTDVKKRLERALMET-----------EAPLQVARECLFHREKRMG 207 I E++ + + +A + + + ERA+ E E L+V ++ E+R+G Sbjct: 1353 IRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLG 1412 Query: 208 IDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRI 267 DL D E+Q + C +R+ L L + HELEK KQ Sbjct: 1413 -DLQADSEESQRALQQLKKKC--QRLTAELQDTKLHLEGQQVRNHELEK----KQ----- 1460 Query: 268 DDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIEN 327 R D+ +S A Q E+ KL+ + ++ Sbjct: 1461 --------------------RRFDSELSQAHEEA----------QREKLQREKLQRE-KD 1489 Query: 328 LLVVTANEMWNQFNKVNLS---FTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKK 384 +L+ A + Q + ++ FT ++ ++ L + + E ++ +KK Sbjct: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQKVVS-------LEAELQDISSQESKDEASLAKVKK 1542 Query: 385 AIKDKTAFLKVAQTRLDERT------RRPNIELCRDMAQLR------LVNEVHEVDDTIQ 432 ++D A +K + LDE+ + + L +M ++R + + EV++ Q Sbjct: 1543 QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ 1602 Query: 433 TLQQRLRDAEDTL-------QSLVHIKATLEYDLAVKANSL-YIDQEKCMSMRKSYPNTL 484 + Q++L+ E L Q ++ K LE LA ++ + D E +RK T Sbjct: 1603 SCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTK 1662 Query: 485 RLV 487 L+ Sbjct: 1663 ALL 1665 >gi|28416946 myosin 18A isoform a [Homo sapiens] Length = 2054 Score = 40.4 bits (93), Expect = 0.004 Identities = 91/423 (21%), Positives = 170/423 (40%), Gaps = 90/423 (21%) Query: 102 SNLTNYQESNTSRHNSEKLRVDTS-RLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEI 160 S LT+ E NT S+ L +T+ RL +K + +TQ D + E V ++ ++ + Sbjct: 1296 SELTD--ERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME-VMEMEVMEARL 1352 Query: 161 IH--ELDEMIGETNALTDVKKRLERALMET-----------EAPLQVARECLFHREKRMG 207 I E++ + + +A + + + ERA+ E E L+V ++ E+R+G Sbjct: 1353 IRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLG 1412 Query: 208 IDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRI 267 DL D E+Q + C +R+ L L + HELEK KQ Sbjct: 1413 -DLQADSEESQRALQQLKKKC--QRLTAELQDTKLHLEGQQVRNHELEK----KQ----- 1460 Query: 268 DDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIEN 327 R D+ +S A Q E+ KL+ + ++ Sbjct: 1461 --------------------RRFDSELSQAHEEA----------QREKLQREKLQRE-KD 1489 Query: 328 LLVVTANEMWNQFNKVNLS---FTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKK 384 +L+ A + Q + ++ FT ++ ++ L + + E ++ +KK Sbjct: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQKVVS-------LEAELQDISSQESKDEASLAKVKK 1542 Query: 385 AIKDKTAFLKVAQTRLDERT------RRPNIELCRDMAQLR------LVNEVHEVDDTIQ 432 ++D A +K + LDE+ + + L +M ++R + + EV++ Q Sbjct: 1543 QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ 1602 Query: 433 TLQQRLRDAEDTL-------QSLVHIKATLEYDLAVKANSL-YIDQEKCMSMRKSYPNTL 484 + Q++L+ E L Q ++ K LE LA ++ + D E +RK T Sbjct: 1603 SCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTK 1662 Query: 485 RLV 487 L+ Sbjct: 1663 ALL 1665 >gi|87298937 centrosomal protein 110kDa [Homo sapiens] Length = 2325 Score = 40.0 bits (92), Expect = 0.005 Identities = 76/373 (20%), Positives = 149/373 (39%), Gaps = 43/373 (11%) Query: 108 QESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEM 167 QE + + L D S + Q + Q+ R+ + L + + K +++H Sbjct: 1836 QELDQLNRDKLSLHNDISAM-QQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQ 1894 Query: 168 IGETNALTDVKKRLERALMETEAPLQVARECLFHRE-KRMGIDLVHDEVEAQLLTEVDTI 226 + L + RL++ + E + +C E K+ + ++ +E+E L V Sbjct: 1895 ----DVLLSEQTRLQKDISEWANRFE---DCQKEEETKQQQLQVLQNEIEENKLKLVQQE 1947 Query: 227 LCCQERMKLHLDKAIAQLAANRAS----QHELEKDLSDKQTAYRIDDKCHHLRNTSDGVG 282 + Q R++ + ++L ++ + QH+LEK+L+D+++ ++D + + V Sbjct: 1948 MMFQ-RLQKERESEESKLETSKVTLKEQQHQLEKELTDQKS--KLDQVLSKVLAAEERVR 2004 Query: 283 YFRGVER----VDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWN 338 + ER ++ T+S + + ++ E A K D + + N+ Sbjct: 2005 TLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLT 2064 Query: 339 QFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQT 398 + K ++A +A ++ L K L E Q I+ K+ VAQ Sbjct: 2065 ERKKAE----KQVASLKEALKIQRSQLEKNLLEQKQENSCIQ------KEMATIELVAQD 2114 Query: 399 RLDERTRR----------PNIELCRDMA-QLRLVNEVHEVDDTIQTLQQRLRD-AEDTLQ 446 ER RR EL + MA Q L E+ D ++TL+ ++D +L+ Sbjct: 2115 N-HERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLK 2173 Query: 447 SLVHIKATLEYDL 459 +L L DL Sbjct: 2174 NLNQFLPELPADL 2186 >gi|33946313 ninein isoform 4 [Homo sapiens] Length = 2096 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/225 (22%), Positives = 92/225 (40%), Gaps = 42/225 (18%) Query: 159 EIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQ 218 EI+ LD + LT++ LE L+ T+ + A F E R Sbjct: 330 EILKALDFSLDGNINLTELTLALENELLVTKNSIHQAALASFKAEIR------------H 377 Query: 219 LLTEVDTILCCQERMKLHLDKA--IAQLAANRASQHELEKDLSDKQTAYRIDDKC----- 271 LL VD ++ +E+++ LDKA + L A+ H + ++ ++D++ Sbjct: 378 LLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIA 437 Query: 272 ---HHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENL 328 + LR + + G +R++ + ++ T++N +R + A S K +EN Sbjct: 438 ALKNELRKEREQILQQAGKQRLELEQEIEKA---KTEENYIRDR--LALSLKENSRLENE 492 Query: 329 LVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIF 373 L+ A ++AE + NK+Q +L L E F Sbjct: 493 LLENA---------------EKLAEYENLTNKLQRNLENVLAEKF 522 >gi|33946321 ninein isoform 5 [Homo sapiens] Length = 2090 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/225 (22%), Positives = 92/225 (40%), Gaps = 42/225 (18%) Query: 159 EIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQ 218 EI+ LD + LT++ LE L+ T+ + A F E R Sbjct: 324 EILKALDFSLDGNINLTELTLALENELLVTKNSIHQAALASFKAEIR------------H 371 Query: 219 LLTEVDTILCCQERMKLHLDKA--IAQLAANRASQHELEKDLSDKQTAYRIDDKC----- 271 LL VD ++ +E+++ LDKA + L A+ H + ++ ++D++ Sbjct: 372 LLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIA 431 Query: 272 ---HHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENL 328 + LR + + G +R++ + ++ T++N +R + A S K +EN Sbjct: 432 ALKNELRKEREQILQQAGKQRLELEQEIEKA---KTEENYIRDR--LALSLKENSRLENE 486 Query: 329 LVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIF 373 L+ A ++AE + NK+Q +L L E F Sbjct: 487 LLENA---------------EKLAEYENLTNKLQRNLENVLAEKF 516 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.129 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,001,505 Number of Sequences: 37866 Number of extensions: 639696 Number of successful extensions: 2694 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 133 Number of HSP's that attempted gapping in prelim test: 2494 Number of HSP's gapped (non-prelim): 314 length of query: 490 length of database: 18,247,518 effective HSP length: 106 effective length of query: 384 effective length of database: 14,233,722 effective search space: 5465749248 effective search space used: 5465749248 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.