Search of human proteins with 7657058

Search of human proteins with 7657058

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657058 eukaryotic translation initiation factor 2B, subunit
2 beta, 39kDa [Homo sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657058 eukaryotic translation initiation factor 2B, subunit ...   693   0.0  
gi|4503503 eukaryotic translation initiation factor 2B, subunit ...    91   1e-18
gi|78000158 eukaryotic translation initiation factor 2B, subunit...    87   2e-17
gi|78000156 eukaryotic translation initiation factor 2B, subunit...    87   2e-17
gi|187607323 eukaryotic translation initiation factor 2B, subuni...    87   2e-17
gi|72534748 translation initiation factor eIF-2B subunit alpha/b...    60   3e-09
gi|23943880 translation initiation factor eIF-2B subunit alpha/b...    58   1e-08
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is...    32   0.65 
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso...    32   0.65 
gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo sap...    31   1.9  
gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo sapi...    31   1.9  
gi|5901898 leucine rich repeat containing 23 isoform b [Homo sap...    30   3.2  
gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens]       30   4.2  
gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens]     30   4.2  
gi|242117893 BCL2-associated X protein isoform sigma [Homo sapiens]    30   4.2  
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s...    30   4.2  
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa...    30   4.2  
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]          29   7.2  
gi|33188443 microfilament and actin filament cross-linker protei...    28   9.4  
gi|33188445 microfilament and actin filament cross-linker protei...    28   9.4  
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ...    28   9.4  
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ...    28   9.4  

>gi|7657058 eukaryotic translation initiation factor 2B, subunit 2
           beta, 39kDa [Homo sapiens]
          Length = 351

 Score =  693 bits (1789), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60
           MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL
Sbjct: 1   MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60

Query: 61  IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE 120
           IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE
Sbjct: 61  IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE 120

Query: 121 DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE 180
           DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE
Sbjct: 121 DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE 180

Query: 181 AARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTIL 240
           AARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTIL
Sbjct: 181 AARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTIL 240

Query: 241 ANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG 300
           ANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG
Sbjct: 241 ANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG 300

Query: 301 DILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 351
           DILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL
Sbjct: 301 DILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 351


>gi|4503503 eukaryotic translation initiation factor 2B, subunit 1
           alpha, 26kDa [Homo sapiens]
          Length = 305

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 66/221 (29%), Positives = 105/221 (47%), Gaps = 4/221 (1%)

Query: 126 YAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARK 184
           Y++ +  +IE     L  +  +   IA      I     I+T  +SR V   L+ A A K
Sbjct: 86  YSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAK 145

Query: 185 RKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGA 244
           ++F V V E  P   G +MA  L    +  TV+ DAA+  +M + + VI+G + ++ NG 
Sbjct: 146 KRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGG 205

Query: 245 LRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFP-NEEDSFHKFVAPEEVLPFTEGDIL 303
           +    GT+ +A+ AK  + P  V A  FK    FP N++D   KF    + L   +    
Sbjct: 206 IINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTG-- 263

Query: 304 EKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELY 344
           + +    P  DY  P LITL  +++G   PS +   + +LY
Sbjct: 264 QDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLY 304


>gi|78000158 eukaryotic translation initiation factor 2B, subunit 4
           delta isoform 2 [Homo sapiens]
          Length = 523

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 13/230 (5%)

Query: 109 LHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTI 168
           L+K +TS G ++      ++L++ I   + E +V      + I+  A + I + +VI+  
Sbjct: 280 LNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVL---AAQAISRFAYQKISNGDVILVY 336

Query: 169 GFSRTVEAFLKEA-ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMS 227
           G S  V   L+EA    R+F V+V +  P+ +G     +L  AG+  + +   A   V+ 
Sbjct: 337 GCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLP 396

Query: 228 RVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHK 287
            V+KV++G   +LANG++ +  GT  LAL A+ H+ P++VC   +K   +   +    ++
Sbjct: 397 EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE 456

Query: 288 FVAPEEVLPFTEGD--ILEKVSVHCP------VFDYVPPELITLFISNIG 329
              P++ L    G+   L     H        V+D  PPEL+ L I+ +G
Sbjct: 457 LDDPDD-LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG 505


>gi|78000156 eukaryotic translation initiation factor 2B, subunit 4
           delta isoform 3 [Homo sapiens]
          Length = 522

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 13/230 (5%)

Query: 109 LHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTI 168
           L+K +TS G ++      ++L++ I   + E +V      + I+  A + I + +VI+  
Sbjct: 279 LNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVL---AAQAISRFAYQKISNGDVILVY 335

Query: 169 GFSRTVEAFLKEA-ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMS 227
           G S  V   L+EA    R+F V+V +  P+ +G     +L  AG+  + +   A   V+ 
Sbjct: 336 GCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLP 395

Query: 228 RVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHK 287
            V+KV++G   +LANG++ +  GT  LAL A+ H+ P++VC   +K   +   +    ++
Sbjct: 396 EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE 455

Query: 288 FVAPEEVLPFTEGD--ILEKVSVHCP------VFDYVPPELITLFISNIG 329
              P++ L    G+   L     H        V+D  PPEL+ L I+ +G
Sbjct: 456 LDDPDD-LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG 504


>gi|187607323 eukaryotic translation initiation factor 2B, subunit 4
           delta isoform 1 [Homo sapiens]
          Length = 543

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 13/230 (5%)

Query: 109 LHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTI 168
           L+K +TS G ++      ++L++ I   + E +V      + I+  A + I + +VI+  
Sbjct: 300 LNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVL---AAQAISRFAYQKISNGDVILVY 356

Query: 169 GFSRTVEAFLKEA-ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMS 227
           G S  V   L+EA    R+F V+V +  P+ +G     +L  AG+  + +   A   V+ 
Sbjct: 357 GCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLP 416

Query: 228 RVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHK 287
            V+KV++G   +LANG++ +  GT  LAL A+ H+ P++VC   +K   +   +    ++
Sbjct: 417 EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE 476

Query: 288 FVAPEEVLPFTEGD--ILEKVSVHCP------VFDYVPPELITLFISNIG 329
              P++ L    G+   L     H        V+D  PPEL+ L I+ +G
Sbjct: 477 LDDPDD-LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG 525


>gi|72534748 translation initiation factor eIF-2B subunit
           alpha/beta/delta-like protein isoform 1 [Homo sapiens]
          Length = 369

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 48/174 (27%), Positives = 76/174 (43%), Gaps = 5/174 (2%)

Query: 165 IMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIF 223
           + T G+   +       +  R  H    E  P+ QG  + A  L    I  T++TD+ + 
Sbjct: 173 LATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVA 232

Query: 224 AVMSR--VNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNE 281
           A M+   V+ V++G   ++ANG      GT+ LA+ AKHH  P  V AP      +    
Sbjct: 233 AAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETG 292

Query: 282 EDSFHKFVAPEEVLPFTEGDILEK-VSVHCPVFDYVPPELIT-LFISNIGGNAP 333
           ++   +    +E+       I    + V  P FD  P +LIT   I+ +G  AP
Sbjct: 293 KEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAP 346


>gi|23943880 translation initiation factor eIF-2B subunit
           alpha/beta/delta-like protein isoform 2 [Homo sapiens]
          Length = 322

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 5/148 (3%)

Query: 191 VAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR--VNKVIIGTKTILANGALRA 247
           V E  P+ QG  + A  L    I  T++TD+ + A M+   V+ V++G   ++ANG    
Sbjct: 152 VLETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTAN 211

Query: 248 VTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEK-V 306
             GT+ LA+ AKHH  P  V AP      +    ++   +    +E+       I    +
Sbjct: 212 KVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGI 271

Query: 307 SVHCPVFDYVPPELIT-LFISNIGGNAP 333
            V  P FD  P +LIT   I+ +G  AP
Sbjct: 272 GVWNPAFDVTPHDLITGGIITELGVFAP 299


>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
           isoform alpha [Homo sapiens]
          Length = 903

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 20/153 (13%)

Query: 5   AAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRRE 64
           AA+  +LSE  E  +ETL      R++ E  R+T       + +H  +   E    + RE
Sbjct: 336 AARAGQLSEHRE--LETL------RAALEEERQTWAQQEHQLKEHYQALQEESQAQLERE 387

Query: 65  GRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSF 124
             +       E       +  L +++ E  RL G  D + ++    +L        + S 
Sbjct: 388 KEK----SQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQL--------EMSL 435

Query: 125 HYAQLQSNIIEAINELLVELEGTMENIAAQALE 157
             A+ +S  I+  +EL V+LE  +    AQA E
Sbjct: 436 VQARYESQRIQLESELAVQLEQRVTERLAQAQE 468


>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
           isoform beta [Homo sapiens]
          Length = 925

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 20/153 (13%)

Query: 5   AAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRRE 64
           AA+  +LSE  E  +ETL      R++ E  R+T       + +H  +   E    + RE
Sbjct: 336 AARAGQLSEHRE--LETL------RAALEEERQTWAQQEHQLKEHYQALQEESQAQLERE 387

Query: 65  GRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSF 124
             +       E       +  L +++ E  RL G  D + ++    +L        + S 
Sbjct: 388 KEK----SQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQL--------EMSL 435

Query: 125 HYAQLQSNIIEAINELLVELEGTMENIAAQALE 157
             A+ +S  I+  +EL V+LE  +    AQA E
Sbjct: 436 VQARYESQRIQLESELAVQLEQRVTERLAQAQE 468


>gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo
           sapiens]
          Length = 698

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 32  EEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTV----GNMVRRVLK 87
           E+ +RE LG   ++  +HR  +  +++ L  RE  +    Q  +  +    G +  R L 
Sbjct: 192 EKSSREALGHQEKLKAEHR--HRAKILNLKLREAEQQRVKQAEQERLRKEEGQIRLRALY 249

Query: 88  IIREEYGRLHGRSDESDQQESLHKL 112
            ++EE  +L  + D S+Q ++L K+
Sbjct: 250 ALQEEMLQLSQQLDASEQHKALLKV 274


>gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo
           sapiens]
          Length = 659

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 32  EEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTV----GNMVRRVLK 87
           E+ +RE LG   ++  +HR  +  +++ L  RE  +    Q  +  +    G +  R L 
Sbjct: 192 EKSSREALGHQEKLKAEHR--HRAKILNLKLREAEQQRVKQAEQERLRKEEGQIRLRALY 249

Query: 88  IIREEYGRLHGRSDESDQQESLHKL 112
            ++EE  +L  + D S+Q ++L K+
Sbjct: 250 ALQEEMLQLSQQLDASEQHKALLKV 274


>gi|5901898 leucine rich repeat containing 23 isoform b [Homo
           sapiens]
          Length = 312

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 15/140 (10%)

Query: 61  IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE 120
           ++ +G R+ +AQ +E     +       I +  G  H R +  + + +   ++T     +
Sbjct: 118 LKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEK 177

Query: 121 DFSFHYAQLQSNIIEA--------------INELLVELEGTMENIAAQALEHIHSNEVIM 166
             S H  +L+ N +E+                 +L ++EG +E+++     H+  N++  
Sbjct: 178 LISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEG-LEDLSNLTTLHLRDNQIDT 236

Query: 167 TIGFSRTVEAFLKEAARKRK 186
             GFSR +++      R+ K
Sbjct: 237 LSGFSREMKSLQYLNLRRSK 256


>gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens]
          Length = 218

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 24 RGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60
          RGGGP SSE++ +    LL+  I D      GE  EL
Sbjct: 9  RGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPEL 45


>gi|20631958 BCL2-associated X protein isoform alpha [Homo
          sapiens]
          Length = 192

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 24 RGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60
          RGGGP SSE++ +    LL+  I D      GE  EL
Sbjct: 9  RGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPEL 45


>gi|242117893 BCL2-associated X protein isoform sigma [Homo
          sapiens]
          Length = 179

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 16/37 (43%), Positives = 20/37 (54%)

Query: 24 RGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60
          RGGGP SSE++ +    LL+  I D      GE  EL
Sbjct: 9  RGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPEL 45


>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 25/130 (19%), Positives = 57/130 (43%), Gaps = 15/130 (11%)

Query: 61  IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE 120
           ++ +G R+ +AQ +E     +       I +  G  H R +  + + +   ++T     +
Sbjct: 118 LKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEK 177

Query: 121 DFSFHYAQLQSNIIEA--------------INELLVELEGTMENIAAQALEHIHSNEVIM 166
             S H  +L+ N +E+                 +L ++EG +E+++     H+  N++  
Sbjct: 178 LISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEG-LEDLSNLTTLHLRDNQIDT 236

Query: 167 TIGFSRTVEA 176
             GFSR +++
Sbjct: 237 LSGFSREMKS 246


>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 25/130 (19%), Positives = 57/130 (43%), Gaps = 15/130 (11%)

Query: 61  IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE 120
           ++ +G R+ +AQ +E     +       I +  G  H R +  + + +   ++T     +
Sbjct: 118 LKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEK 177

Query: 121 DFSFHYAQLQSNIIEA--------------INELLVELEGTMENIAAQALEHIHSNEVIM 166
             S H  +L+ N +E+                 +L ++EG +E+++     H+  N++  
Sbjct: 178 LISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEG-LEDLSNLTTLHLRDNQIDT 236

Query: 167 TIGFSRTVEA 176
             GFSR +++
Sbjct: 237 LSGFSREMKS 246


>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
          Length = 311

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 7/103 (6%)

Query: 102 ESDQQESLHKLLTSGGLNEDFSFHYAQ----LQSNIIEAINELLVELEGTMENIAAQALE 157
           E+   E+L + LT   L+       AQ    +Q  +   +N   + L G +E ++  A++
Sbjct: 49  EAAAGEALGQTLTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQ 108

Query: 158 HIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQG 200
           ++         G  R V+A L    R+R+ H++V       QG
Sbjct: 109 NVFDTNFF---GAVRLVKAVLPGMKRRRQGHIVVISSVMGLQG 148


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 23/94 (24%), Positives = 40/94 (42%), Gaps = 13/94 (13%)

Query: 13   ERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGEL-------MELIRREG 65
            ER E  +E + +GG    +     +  G   + +  H+    G+L        +++  E 
Sbjct: 2334 ERSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHK----GDLRFVTISGQKVLDMEN 2389

Query: 66   RRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGR 99
                  +PSE  +GN+V+  LK   E Y  LH +
Sbjct: 2390 SFKEGKEPSE--IGNLVKDKLKDATERYTALHSK 2421


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 23/94 (24%), Positives = 40/94 (42%), Gaps = 13/94 (13%)

Query: 13   ERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGEL-------MELIRREG 65
            ER E  +E + +GG    +     +  G   + +  H+    G+L        +++  E 
Sbjct: 1832 ERSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHK----GDLRFVTISGQKVLDMEN 1887

Query: 66   RRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGR 99
                  +PSE  +GN+V+  LK   E Y  LH +
Sbjct: 1888 SFKEGKEPSE--IGNLVKDKLKDATERYTALHSK 1919


>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
           precursor [Homo sapiens]
          Length = 908

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 6/49 (12%)

Query: 171 SRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTD 219
           ++  +  LKE  R ++FHVI      F   HEMA  + K  +   +MT+
Sbjct: 208 TKDAKPLLKEMKRGKEFHVI------FDCSHEMAAGILKQALAMGMMTE 250


>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
           precursor [Homo sapiens]
          Length = 869

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 6/49 (12%)

Query: 171 SRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTD 219
           ++  +  LKE  R ++FHVI      F   HEMA  + K  +   +MT+
Sbjct: 208 TKDAKPLLKEMKRGKEFHVI------FDCSHEMAAGILKQALAMGMMTE 250


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,169,288
Number of Sequences: 37866
Number of extensions: 495507
Number of successful extensions: 1223
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1208
Number of HSP's gapped (non-prelim): 22
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.