Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 75677365
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
(4427 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 8874 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 2597 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 2520 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 2454 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2437 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 2425 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 2205 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2194 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2162 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2162 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 2141 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 2130 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 2086 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1427 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1357 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 1145 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 893 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 486 e-136
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 261 8e-69
gi|71061468 centromere protein E [Homo sapiens] 59 1e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 58 2e-07
gi|21735548 centrosomal protein 2 [Homo sapiens] 54 3e-06
gi|112420968 coiled-coil domain containing 158 [Homo sapiens] 52 1e-05
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 52 1e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 52 2e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 52 2e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 50 4e-05
gi|118498356 kinectin 1 isoform a [Homo sapiens] 49 1e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 49 1e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens] 49 1e-04
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 8874 bits (23027), Expect = 0.0
Identities = 4427/4427 (100%), Positives = 4427/4427 (100%)
Query: 1 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE 60
MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
Sbjct: 1 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE 60
Query: 61 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP 120
GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
Sbjct: 61 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP 120
Query: 121 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA 180
CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
Sbjct: 121 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA 180
Query: 181 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE 240
PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
Sbjct: 181 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE 240
Query: 241 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV 300
LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
Sbjct: 241 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV 300
Query: 301 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK 360
KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
Sbjct: 301 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK 360
Query: 361 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI 420
LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
Sbjct: 361 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI 420
Query: 421 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE 480
TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE
Sbjct: 421 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE 480
Query: 481 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY 540
LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
Sbjct: 481 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY 540
Query: 541 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ 600
VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
Sbjct: 541 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ 600
Query: 601 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN 660
EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
Sbjct: 601 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN 660
Query: 661 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK 720
VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
Sbjct: 661 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK 720
Query: 721 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED 780
GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
Sbjct: 721 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED 780
Query: 781 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV 840
QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
Sbjct: 781 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV 840
Query: 841 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL 900
KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
Sbjct: 841 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL 900
Query: 901 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD 960
FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
Sbjct: 901 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD 960
Query: 961 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL 1020
MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
Sbjct: 961 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL 1020
Query: 1021 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA 1080
KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
Sbjct: 1021 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA 1080
Query: 1081 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK 1140
LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
Sbjct: 1081 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK 1140
Query: 1141 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE 1200
HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
Sbjct: 1141 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE 1200
Query: 1201 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM 1260
NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
Sbjct: 1201 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM 1260
Query: 1261 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR 1320
ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
Sbjct: 1261 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR 1320
Query: 1321 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL 1380
DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
Sbjct: 1321 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL 1380
Query: 1381 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI 1440
DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
Sbjct: 1381 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI 1440
Query: 1441 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP 1500
EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
Sbjct: 1441 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP 1500
Query: 1501 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK 1560
GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
Sbjct: 1501 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK 1560
Query: 1561 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT 1620
KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
Sbjct: 1561 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT 1620
Query: 1621 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK 1680
LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
Sbjct: 1621 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK 1680
Query: 1681 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL 1740
VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
Sbjct: 1681 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL 1740
Query: 1741 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS 1800
SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
Sbjct: 1741 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS 1800
Query: 1801 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI 1860
PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
Sbjct: 1801 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI 1860
Query: 1861 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK 1920
NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
Sbjct: 1861 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK 1920
Query: 1921 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL 1980
SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
Sbjct: 1921 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL 1980
Query: 1981 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID 2040
TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
Sbjct: 1981 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID 2040
Query: 2041 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS 2100
YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
Sbjct: 2041 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS 2100
Query: 2101 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD 2160
LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
Sbjct: 2101 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD 2160
Query: 2161 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS 2220
EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
Sbjct: 2161 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS 2220
Query: 2221 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE 2280
RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
Sbjct: 2221 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE 2280
Query: 2281 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY 2340
YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
Sbjct: 2281 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY 2340
Query: 2341 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY 2400
LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
Sbjct: 2341 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY 2400
Query: 2401 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES 2460
LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
Sbjct: 2401 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES 2460
Query: 2461 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK 2520
RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
Sbjct: 2461 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK 2520
Query: 2521 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE 2580
YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
Sbjct: 2521 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE 2580
Query: 2581 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI 2640
VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
Sbjct: 2581 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI 2640
Query: 2641 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP 2700
TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
Sbjct: 2641 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP 2700
Query: 2701 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL 2760
KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
Sbjct: 2701 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL 2760
Query: 2761 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV 2820
VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
Sbjct: 2761 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV 2820
Query: 2821 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE 2880
DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
Sbjct: 2821 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE 2880
Query: 2881 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG 2940
RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
Sbjct: 2881 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG 2940
Query: 2941 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL 3000
TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
Sbjct: 2941 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL 3000
Query: 3001 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ 3060
LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
Sbjct: 3001 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ 3060
Query: 3061 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP 3120
KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
Sbjct: 3061 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP 3120
Query: 3121 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD 3180
AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
Sbjct: 3121 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD 3180
Query: 3181 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK 3240
FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
Sbjct: 3181 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK 3240
Query: 3241 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL 3300
LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
Sbjct: 3241 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL 3300
Query: 3301 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN 3360
EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
Sbjct: 3301 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN 3360
Query: 3361 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ 3420
PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
Sbjct: 3361 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ 3420
Query: 3421 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN 3480
MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
Sbjct: 3421 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN 3480
Query: 3481 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN 3540
FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
Sbjct: 3481 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN 3540
Query: 3541 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT 3600
IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
Sbjct: 3541 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT 3600
Query: 3601 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID 3660
DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
Sbjct: 3601 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID 3660
Query: 3661 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG 3720
YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
Sbjct: 3661 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG 3720
Query: 3721 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE 3780
QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
Sbjct: 3721 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE 3780
Query: 3781 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI 3840
NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
Sbjct: 3781 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI 3840
Query: 3841 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL 3900
LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
Sbjct: 3841 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL 3900
Query: 3901 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL 3960
SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
Sbjct: 3901 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL 3960
Query: 3961 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL 4020
YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
Sbjct: 3961 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL 4020
Query: 4021 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA 4080
LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
Sbjct: 4021 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA 4080
Query: 4081 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI 4140
LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
Sbjct: 4081 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI 4140
Query: 4141 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM 4200
TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
Sbjct: 4141 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM 4200
Query: 4201 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR 4260
QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR
Sbjct: 4201 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR 4260
Query: 4261 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN 4320
VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
Sbjct: 4261 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN 4320
Query: 4321 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS 4380
LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
Sbjct: 4321 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS 4380
Query: 4381 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS 4427
CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
Sbjct: 4381 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS 4427
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 2597 bits (6732), Expect = 0.0
Identities = 1427/3666 (38%), Positives = 2190/3666 (59%), Gaps = 137/3666 (3%)
Query: 872 DLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTI---------SVFCHLPDILTKRKLHRE 922
+L +V + F P+L+ + NH +T+ S F KL +
Sbjct: 516 ELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGK 575
Query: 923 PIQT------VVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHR 976
T V E D++ I +QI + + Y T++ ++ ++ N+ +
Sbjct: 576 TCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQIFFKENESLDLQA 635
Query: 977 YQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQ---HCNEWQN 1033
+ P ++ F + +Y + + N+ +L+D L+ L+ C E N
Sbjct: 636 LKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLN 695
Query: 1034 KFATLLREMAAGRLLELHTYLKENAE-KISRPPQTLEELGVSLQLVDALKHDLANVETQI 1092
+ + + ++ + ++AE K+ P T E SL +D ++ + ++E +
Sbjct: 696 ----FMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEG 751
Query: 1093 PPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHS 1152
+ + + ++E+Y+VP + ++ V + + S + + K +H
Sbjct: 752 NIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKS---VGDRESSIKQFCVHL 808
Query: 1153 ADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQI----TQVRAMLMAMREEENSLRANLG 1208
D ++ + + + + + + + D+I ++++L +++ ++
Sbjct: 809 GSDLEE-LNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAFQYKSYQK 867
Query: 1209 IFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLF 1268
FK+E + L+ + EL Q +W+ +W++ EW +F L E +
Sbjct: 868 NFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQVSKYA 927
Query: 1269 RRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFD 1328
+ +T+L K + ++ + K+E+ K +P+I DLRNP L+ RHW + +
Sbjct: 928 KFVTQLEKGLPPNS--VVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLV 985
Query: 1329 QESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKD- 1387
TLE++ +L + ++I +IS A+ E A+E L+ + +W T+ I+P++D
Sbjct: 986 DAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHRDS 1045
Query: 1388 KGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQ 1447
K L GT+++ L+D+ + ++T+ +SR++ + VD W++ L+L + +E LT Q
Sbjct: 1046 KDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQ 1105
Query: 1448 RQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLI 1507
R W+YLE+IF DI++QLP E+ +F QV+ +WK IM ++N+ NALR+ PGLL+T
Sbjct: 1106 RNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQ 1165
Query: 1508 EMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIK 1567
N +L+ IQK L+ YLE+KR IFPRFYFLSND+LLEIL Q+RNP+AVQPHL+KCFD+I
Sbjct: 1166 NNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSIS 1225
Query: 1568 LLRIQ-------KVGGPSSKWEAV------GMFSGDGEYIDFLHSVFLEGPVESWLGDVE 1614
L K+ G + E V M S +GE + + G VE WLG VE
Sbjct: 1226 KLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVE 1285
Query: 1615 QTMRVTLRDLLRNCHLALRKFLNK-RDKWVKEW-AGQVVITASQIQWTADVTKCLLTAKE 1672
+ M +LR L C A+ + K R WV QV++T SQI W D+T+CL T
Sbjct: 1286 EAMFTSLRRL---CKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECLETEHS 1342
Query: 1673 RADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLM 1732
+ LK +K LN + ++G+L K+ R + AL+TI++HARD++ +L +S +
Sbjct: 1343 N-HIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSKVE 1401
Query: 1733 DVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTA 1792
V SFDW QLR+YW+ DLD+CV R +Q+ Y YEYLG RLVITPLTDRCY+ L A
Sbjct: 1402 TVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGA 1461
Query: 1793 LHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWG 1852
L L GG+P GPAGTGKTET KDL KAL I +V NCS+GLDYK MGR +SGLAQ+GAW
Sbjct: 1462 LQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWC 1521
Query: 1853 CFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGR 1912
CFDEFNRI+IEVLSV+A Q++ I +A AA L+ F F+G EI LV +C FITMNPGYAGR
Sbjct: 1522 CFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYAGR 1581
Query: 1913 TELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDH 1972
TELP+NLK++FRP AM+VP+ LIAE+IL+ EGF + KILA+K+ +Y L +QLS+QDH
Sbjct: 1582 TELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDH 1641
Query: 1973 YDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFP 2032
YDFG+RA+ S+L AG +R PDL ++ VL+ +++D N+ K + DA LF+ I+ DLFP
Sbjct: 1642 YDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFP 1701
Query: 2033 NIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTA 2092
+++P DYG L+ T+ + LQ + KV Q YET RH M+VG TG GKT
Sbjct: 1702 GVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTT 1761
Query: 2093 SWRILQASLSSLCRAGDPN--FNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVM 2150
+RIL +L +L + G N + V+ + LNPK++++GELYGE + T EW DG+++ +
Sbjct: 1762 VYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSV 1821
Query: 2151 RTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVED 2210
R A D D KWI+ DGPVD LWIENMN+V+DDNK+L L N ERI + Q+ +LFEV+D
Sbjct: 1822 RAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQD 1881
Query: 2211 LAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQ----RMFEKLINKMLA 2266
L +ASPATVSRCGMV+ D +L W PYV++W++ K E Q +F++ +++ L
Sbjct: 1882 LRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLH 1941
Query: 2267 FKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPADGENYV-TMVEMTFVFSMIWSV 2325
F C + +P + S +T+LC L +L ++GVN A + + T++ TFVF +WS+
Sbjct: 1942 FINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSL 2001
Query: 2326 CASVDEEGRKRIDSYLR-----EIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYP 2380
++ E D+++R + PN ++ +D + +E +P +++Y
Sbjct: 2002 GGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIP-TFKYN 2060
Query: 2381 PNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSV 2440
+ PF++++VPT DTVRY YL+ L+A ++ +L G G GK+ IA+ +L + S V
Sbjct: 2061 RDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYV 2120
Query: 2441 LV-VNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPL 2499
V +N SAQT+S Q IIES++E++ K + G K ++ F+DDLNMP D +GSQPP+
Sbjct: 2121 PVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPI 2180
Query: 2500 ELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTK 2559
EL+R + D+G +YDR K K I+++ +++A PPGGGR ++PR F+++ + P++
Sbjct: 2181 ELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSE 2240
Query: 2560 SQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDI 2619
+ +IF ++N L DF VK + + EA++++YN + LPTP K HY+FNLRD+
Sbjct: 2241 HSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDL 2300
Query: 2620 SKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDL 2679
SK QG+L+ + + I RL+ HEC RVF DRL++ D F I+++ F +
Sbjct: 2301 SKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGI 2360
Query: 2680 TFHHLCPSKRPPIFGDFL-----KEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQL 2734
+P IFGDF+ K ++Y+D+ D+ V++ L++YNL+ + ++L
Sbjct: 2361 AIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLT-NPKEVKL 2419
Query: 2735 VLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRK 2794
V F++AIEH++RI R+I Q RGN LLVG+GG+G+QSL RLA+ IC Y QIE+++ Y
Sbjct: 2420 VFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNY 2479
Query: 2795 QEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEI 2854
F +D+++LY+ AGVE K F+F DTQI E FLEDINNIL+SGEVPNL++ DE E++
Sbjct: 2480 DSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQV 2539
Query: 2855 QSHIIDQARVEQVPESS-DSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCT 2913
+ +A+ + E + D +F Y I +V+ LHIVLC+SP+G+ FR+ R +P+LVNC
Sbjct: 2540 LAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCC 2599
Query: 2914 TINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRR 2973
TI+WF +WP+EALL V++ VD G +E + K+ + V +H SV+ +++ ELRR
Sbjct: 2600 TIDWFVQWPREALLSVSKTFFSQVDAGNEE-LKEKLPLMCVNVHLSVSSMAERYYNELRR 2658
Query: 2974 HNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKK 3033
Y TPT YLEL++ Y +L EKR+++++ ++++ GL K+ ET V M L+L +
Sbjct: 2659 RYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEP 2718
Query: 3034 KVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALP 3093
+ + E + + + AD+ + V + V+ + QA+AD+AQ+DL+EALP
Sbjct: 2719 VLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALP 2778
Query: 3094 ALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFI 3153
AL+ A +AL+SL+K DI EI+ + +PP V VM+A+ IL +P W AK+ LG+ NF+
Sbjct: 2779 ALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSNFL 2838
Query: 3154 KSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVV 3213
K L+ +DK+NI ++L K+ Y PDF P+ + +VS A KS+CMWVRAM+LY R+ +VV
Sbjct: 2839 KRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVV 2898
Query: 3214 EPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEME 3273
EPKR ++ AA A+L A L E Q LR+V ++++ L+ +YD+ + +KE L K +
Sbjct: 2899 EPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTK 2958
Query: 3274 LKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIV 3333
+L RAG L + L E+ RWEE++Q EE++ + G+ +AAA ++Y G F YR ++
Sbjct: 2959 ARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLI 3018
Query: 3334 NQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWAL 3393
+ WI L++P PSF++ N L +P ++R WN GLP D STENGI+VT+G RW L
Sbjct: 3019 -ECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPL 3077
Query: 3394 MIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNP 3453
MIDPQ QA +WI+N E GLKII L S++LRILE++I G PVLL+ ++E LDP L P
Sbjct: 3078 MIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEP 3137
Query: 3454 MLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQG 3513
+L K + GGRLL+R+GD +++Y+ NFRFY+TTK+ NPHY PE K TI+NF V + G
Sbjct: 3138 ILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSG 3197
Query: 3514 LEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLV 3573
LE QLL VVR E+P LEEQ+ L++ I K +LK +E++ILR+L + G++LD+ +L+
Sbjct: 3198 LEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELI 3257
Query: 3574 NTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQF 3633
+TL SKIT+ + +LE +E+TE ++ARE YRP A + S+++FV+ + IDPMYQ+
Sbjct: 3258 DTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQY 3317
Query: 3634 SLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAK 3693
SL + LF +I+ S ++ L+ R+D L + Y R LFE+HKL++SF +C +
Sbjct: 3318 SLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVE 3377
Query: 3694 ILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDK-LTNFHGL-- 3750
++ G L+ E+NFFLRG L++E + P + WL A W +L++ FHGL
Sbjct: 3378 MMRQQGTLSDAEWNFFLRGSAGLEKE-RPPKPEAPWLPTATWFACCDLEESFPVFHGLTQ 3436
Query: 3751 ----------MNSFEQY--PRDWHLWYTNAAPEKAMLPGE-------WENACNEMQRMLI 3791
+ SFE Y P+ W + +K M + W + ++++
Sbjct: 3437 NILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLIL 3496
Query: 3792 VRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSAL 3851
++ ++++V F +T F+I NLG +FIE P +++ ++ +D + +PLVFILS G DP A
Sbjct: 3497 IKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSDPMGAF 3556
Query: 3852 LQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVE 3911
+ A G ++R ++SLGQGQ PIA +++++ + G+WVFL NCHL++SWM +++L++
Sbjct: 3557 QRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIK 3616
Query: 3912 QLQVEDP--HPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQF 3969
D +FRL+LSS+P FP+++LQ S+K+T EPPKGL+AN+ R + M+ F
Sbjct: 3617 TFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFF 3676
Query: 3970 SRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYE 4029
K+++++F +CFFH+++ ERKKF LGWNI Y FNDSD E + L LY E
Sbjct: 3677 EENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE-G 3735
Query: 4030 ETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKD 4089
+ PWDAL Y+ I YGG VTD WD+R L T + +F ++L + + S YF P
Sbjct: 3736 KIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDY-KYSESGIYFAPMA 3794
Query: 4090 GSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQT 4149
SL +K+YI LP +D PE FG H NA++ Q E TL +T+L +QP+ + T G++
Sbjct: 3795 DSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPR-SSTGGEGKS 3853
Query: 4150 REEKVLELAADVKQKIPEMIDYEGTQKLLALDP-----SPLNVVLLQEIQRYNTLMQTIL 4204
+E V EL A V+ ++PE ++ EG + L + + L VL QE+ R+N L++ I
Sbjct: 3854 NDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIH 3913
Query: 4205 FSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGK-AYPSQKPLAAWTRDLAMRVEQ 4263
SL L K I G +VMS +E+++N + VP LW AYPS KPL +W +DL +R
Sbjct: 3914 TSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSF 3973
Query: 4264 FELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEF-IVSTVDDSNLV 4322
+LW R +P +W+SGF FP GFLT LQ+ AR+ N+ +D LS+++ ++ T D V
Sbjct: 3974 VDLWLKRGQPK-SYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAV 4032
Query: 4323 Y-------------------PPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTI 4363
P+DGV V G++++ + WD K + +A P Q+ ++P +
Sbjct: 4033 IEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVV 4092
Query: 4364 HFRPAESRKKSAKGMYSCPCYYYPNRAG----SSDRASFVIGIDLRSGAMTPDHWIKRGT 4419
HF P ++ K S +Y CP Y RAG + +FV+ + L S + D+WI +G+
Sbjct: 4093 HFEPQQNYKPSPT-LYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPS-KRSKDYWIAKGS 4150
Query: 4420 ALLMSL 4425
ALL L
Sbjct: 4151 ALLCQL 4156
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 2520 bits (6532), Expect = 0.0
Identities = 1441/3777 (38%), Positives = 2170/3777 (57%), Gaps = 179/3777 (4%)
Query: 776 EFEEDQREHRAAVQQKLMN--LHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDR--- 830
EFE+ Q + + VQ L + + V + ++ ++ K + W +Y++ R
Sbjct: 541 EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLM 600
Query: 831 -----MMEDALRLNVKWSLLELSK---------------------AINGDGKTSPNPLFQ 864
M++D LR V+ SL S+ IN + NPLF
Sbjct: 601 ELVKYMLQDTLRFLVQDSLASFSQFISDTCCSVLNCTDDMVWGDDLINSPYRPRKNPLFI 660
Query: 865 VLVILKNDLQGSVAQVEFSPTLQTL-AGVVNDIGNHLFSTISVFCHLPDILTKRKLHREP 923
+ ++L + + V +S L+ A ++N + +T +V ++ + +P
Sbjct: 661 MDLVLDS------SGVHYSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDP 714
Query: 924 IQTVVEQDED-IKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQR--- 979
+ V E +++++ I+S ++ LQ Y K + Y E+ + SF+ YQ
Sbjct: 715 LLESVGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGL 774
Query: 980 LNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLL 1039
L V V R E+ ++ + ++ D ++ Q ++ + AT +
Sbjct: 775 LAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINTD------NVKQSLSKKRKALATSV 828
Query: 1040 REMAAGRLLELHTYLKENAEKISRP----PQTLEELGVSLQLVDALKHDLANVETQIPPI 1095
++ A L + + E ISR P ++EEL + + + L +E +I +
Sbjct: 829 LDILAKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKV 888
Query: 1096 HEQFAILEKYEVPVEDSVLEMLDSLNGEWVV--FQQTLLDSKQMLKKH----KEKFKTGL 1149
+ + +++++ + D N +W+ + +L +++++ +EKF+
Sbjct: 889 MDDYQVMDEFLYNLSS------DDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQ 942
Query: 1150 IHSADDFKKKAHTL-LEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLG 1208
I ++F++K L L F H + + A +++ +V+ L ++
Sbjct: 943 IMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIA-NEVRRVKKQLKDCQQLAMLYNNRER 1001
Query: 1209 IFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLF 1268
IF + L + KE +W A DW W + E +E F
Sbjct: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061
Query: 1269 RRLTKLAKEYKDRN--WEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQRE 1326
+ + K K++KD E+ R++IE+FK +PLI LRNP +R RHW+ + ++I
Sbjct: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121
Query: 1327 FDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYK 1386
++ + T + +E+ + H+E I +++ A KE AIE AL + K W +++PYK
Sbjct: 1122 VRPKA-NLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYK 1180
Query: 1387 DKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTV 1446
+ L+ +E Q L+D+ V M S + K FE+ ++ WE L L EV+E L
Sbjct: 1181 ATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNC 1240
Query: 1447 QRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTL 1506
QR W+YLE IF EDI +QLP ES + + WK IM ++ + +LD+L
Sbjct: 1241 QRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300
Query: 1507 IEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNI 1566
+ N IL+ +QK L YLETKR FPRFYFLS+D+LLEIL Q+++P AVQPHL+KCF+NI
Sbjct: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360
Query: 1567 KLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLR 1626
L Q+ E M+S +GE + S++ VE WL +VE++M+ ++ D++
Sbjct: 1361 ARLLFQE------DLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414
Query: 1627 NCHLALRKFLNK-RDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKN 1685
A+R + R +WV W GQV I Q WT +V + L R+ +
Sbjct: 1415 K---AIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGNLRSQ------LFPQ 1465
Query: 1686 QVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRF 1745
L+ +RG L+++ R + AL+ IE+HA+DV+ KL + ++ VN F W+SQLR+
Sbjct: 1466 LCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRY 1525
Query: 1746 YWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPA 1805
YW + D IR N +F Y YEYLGNSGRLVITPLTDRCY+TLT ALHL GG+P GPA
Sbjct: 1526 YWTNN--DLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPA 1583
Query: 1806 GTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVL 1865
GTGKTET KDLGKAL I +V NCS+ LD+ +MG+ + GLA GAW CFDEFNRI+IEVL
Sbjct: 1584 GTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVL 1643
Query: 1866 SVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRP 1925
SVVA QI I A + F F+G EI LV SC +FITMNPGYAGRTELP+NLK++FRP
Sbjct: 1644 SVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRP 1703
Query: 1926 IAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLR 1985
+AM+VPD +I EI L+ GF +LAKK+ T + L+ +QLS QDHYDFG+RA+ +++
Sbjct: 1704 VAMMVPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVIS 1763
Query: 1986 YAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLR 2045
AG +R P + +E + L ++RD+N+ K D LF+ IV DLFP I+ DYG L
Sbjct: 1764 AAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILD 1823
Query: 2046 ETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLC 2105
E + + R+ L+ LTK QLYET RH M+VG TGSGK+ +R+L A+++SL
Sbjct: 1824 EAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSL- 1882
Query: 2106 RAGDPN-----FNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD 2160
G P+ + V + LNPK++++G+LYGE+DL T+EWTDGI SS +R +
Sbjct: 1883 -KGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTN 1941
Query: 2161 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS 2220
+KW +FDGPVD +WIENMN+V+DDNK L L +GE I + E ++++FEV+DLA+ASPATVS
Sbjct: 1942 KKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVS 2001
Query: 2221 RCGMVYTDYADLGWKPYVQSWLEKRP---KAEVEPLQRMFEKLINKMLAFKKDNCKELVP 2277
RCGMVY + + LG P+++ WL K P K E + +F + + ++F + + KE++
Sbjct: 2002 RCGMVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIA 2061
Query: 2278 LPEYSGITSLCKLYSAL---ATPENGVNPADGE---NYVTMVEMTFVFSMIWSVCASVDE 2331
+ SL KL P G+ E V ++E F+FS+IWSV A+ D
Sbjct: 2062 STNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDS 2121
Query: 2332 EGRKRIDSYLR------EIEGSFPNKDTVYEYFVDP----------------KIRSWTSF 2369
GR +LR ++ FP + V++Y ++ K +W +
Sbjct: 2122 SGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKW 2181
Query: 2370 EDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKT-SIAQS 2428
D + P+ + I+VPT+DTV+ ++L+ L+ N+ P+L +GP GTGKT +I+
Sbjct: 2182 MDS-SAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240
Query: 2429 VLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMP 2488
+L++L S + SA+T++N Q I+S+++KR KGV+ P G++ I F+DDLNMP
Sbjct: 2241 LLKNLALDYISHF-LTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMP 2299
Query: 2489 AKDMFGSQPPLELIRLWIDYGFWYDR-TKQTIKYIREMFLMAAMGPPGGGRTVISPRLRS 2547
A + +G+QPP+EL+R W+D+G WYDR K + ++ + AMGPPGGGR ++PRL
Sbjct: 2300 ALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMR 2359
Query: 2548 RFNIINMTFPTKSQIIRIFGTMINQKL------QDFEEEVKPIGNV------VTEATLDM 2595
FN ++ + RIF T++ L + + E V ++ + EAT+ +
Sbjct: 2360 HFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMV 2419
Query: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655
Y T+ + LPTP K HY FNLRD+SKVFQGML A+ + + + RLW HE RVF DR
Sbjct: 2420 YATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDR 2479
Query: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFL---KEPKVYEDLTDLTVL 2712
LV+ D F ++ + +++TF+ +CP +P ++GDF+ + K YE +T + +
Sbjct: 2480 LVNEEDRSWFDQLLK-RCMEQWEVTFNKVCPF-QPILYGDFMSPGSDVKSYELITSESKM 2537
Query: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772
V+E + +YN + ++LVLF +A+ HI RI R + Q GN LL+G+GGSGR SL
Sbjct: 2538 MQVIEEYIEDYN-QINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLT 2596
Query: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832
RLAS + +Y FQIE++K+Y E+RDD+K++ +AG++ +F+F DTQI +ESFLED
Sbjct: 2597 RLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLED 2656
Query: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCL 2892
INN+L+SG++PNLY DE ++I S + + + + + +L A RV++N+H+VLC+
Sbjct: 2657 INNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCM 2716
Query: 2893 SPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGV-DLGTQENIHRKVAQ 2951
SP+G+ FR +RQ+P+LVNC TI+WF+EWP EAL VA L + +L + + + + Q
Sbjct: 2717 SPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQ 2776
Query: 2952 IFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGL 3011
+ V +H SV++ + L EL RHNYVTP YLELL + L+G+K+ EL N++++GL
Sbjct: 2777 VCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGL 2836
Query: 3012 FKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIA 3071
K+ T E V M +LE + E K + I A+E + +V K
Sbjct: 2837 DKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKAN 2896
Query: 3072 VEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVM 3131
+ K QA+AD+AQKDL+EALPAL+ A+ +L +LNK D+ E+++ RPP V++V++AV
Sbjct: 2897 EKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVC 2956
Query: 3132 ILRGNEPT--------------WAEAKRQLGEQ-NFIKSLINFDKDNISDKVLKKIGAYC 3176
I++G +P W K L + +F++SL FDKDNI D V+K I Y
Sbjct: 2957 IMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYI 3016
Query: 3177 AQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAE 3236
+FQP I +VS A S+C WVRAM Y + + VEPKR + A L Q L E
Sbjct: 3017 DNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDE 3076
Query: 3237 AQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEET 3296
A+++LREV + + ++ +Y E + +KEEL K E+ E +L RAG L++GL+ EK RW+ET
Sbjct: 3077 AKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQET 3136
Query: 3297 VQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDN 3356
V+ L+ L + GD L+AA F++Y+GPF YR ++ W+ ++ VP + +
Sbjct: 3137 VENLQYMLNNISGDVLVAAGFVAYLGPFTGQYR-TVLYDSWVKQLRSHNVPHTSEPTLIG 3195
Query: 3357 FLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKI 3416
L NP K+R W I GLP+D S ENG+I RW IDPQ+QA KWIKNME GL +
Sbjct: 3196 TLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDV 3255
Query: 3417 IDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVE 3476
L D+LR +E+AI FG P LL+NV E LDP L P+L K + G ++++GD +
Sbjct: 3256 FKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIP 3315
Query: 3477 YNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDS 3536
Y+ +FR YITTKL NPHY+PE S K T++NF + GLE QLLG VV +ERP+LEE K+
Sbjct: 3316 YHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQ 3375
Query: 3537 LVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETT 3596
L+I+ A +++LK++ED+IL L+ + G+ +DD++L+ L SK+ A E+ ++ +E T
Sbjct: 3376 LIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQT 3435
Query: 3597 EINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLE 3656
E + DL R Y P A R ILFF ++D+ +DPMYQ+SL+ ++++F+ I S R++ L+
Sbjct: 3436 EKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLK 3495
Query: 3657 DRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVL 3716
RI +N Y TY++Y CR+LFE+HKL+F+F +C +I+ GK+N E+ + L GG +
Sbjct: 3496 KRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSI- 3554
Query: 3717 DREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLP 3776
+NP WL+D W +I L L F + F ++ ++ + + + P + LP
Sbjct: 3555 --SIMTENPAPDWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLP 3612
Query: 3777 GEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSP 3836
G W+ ++ Q++L++R LR D+V + F+ TNL RFIEP N+ V +DS +P
Sbjct: 3613 GIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTP 3672
Query: 3837 LVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANC 3896
L+F+LSPG DP + L + AE M +++ A+SLGQGQ P A ++R + +G WVF NC
Sbjct: 3673 LIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNC 3732
Query: 3897 HLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKAN 3956
HL+ SWMP L++L+E + + H FRLWL+S+P FP+SILQ KMT EPP+G++AN
Sbjct: 3733 HLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRAN 3792
Query: 3957 MTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEV 4016
+ + Y + E + C K ++K LL SLC FH LER+KF LG+NI Y F D D +
Sbjct: 3793 LLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRI 3852
Query: 4017 SENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFH 4076
+ L ++LDEY++ P+ LKY INYGG VTDDWDRR + + D++ LS P H
Sbjct: 3853 CISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLS-PEH 3911
Query: 4077 RLSALETYF-IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLS 4135
SA Y IP L Y YI LP D PE FG H NA++ E L T++
Sbjct: 3912 SYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQ 3971
Query: 4136 LQPQITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQ-KLLALDPSPLNVVLLQEIQ 4194
LQP+ + AG Q REE V ++ ++ K+PE I+ + K L +N VL+QE+
Sbjct: 3972 LQPK--SSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVI 4029
Query: 4195 RYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAW 4253
RYN L+Q I +L DL K ++GL+VMS+ LE + +++ VP LW KAYPS KPL++W
Sbjct: 4030 RYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSW 4089
Query: 4254 TRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIV 4313
DL R++ + W P +FW+SGF FP FLT LQ+ AR+ +S+D++S++F V
Sbjct: 4090 VMDLLQRLDFLQAWIQDG-IPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKV 4148
Query: 4314 STVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKK 4373
S L P+ G ++ GL+LEGA WD + L E++P +L M I P +RK
Sbjct: 4149 MFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKA 4208
Query: 4374 SAKGMYSCPCYYYPNRAG----SSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLD 4426
+ Y CP Y RAG + ++VI +++ + HWIKRG AL+ +LD
Sbjct: 4209 QDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPT-HQPQRHWIKRGVALICALD 4264
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 2454 bits (6360), Expect = 0.0
Identities = 1401/3693 (37%), Positives = 2107/3693 (57%), Gaps = 192/3693 (5%)
Query: 860 NPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK--- 916
+P F + +IL ND ++F P L + ++ + + +S +P + TK
Sbjct: 399 HPGFIMRLILDNDT------IKFEPELSDYIDIFLNVYDVMIKAVSF---VPRVETKLYS 449
Query: 917 ------RKLHREPI---QTVVEQDEDIKKIQTQISSGMTNNASLLQNY--LKTWDMYREI 965
+ +PI + V E IK++ + S T + L Y L T R++
Sbjct: 450 KWESKSKPTTLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDV 509
Query: 966 WEINKDSFI---HRYQRLNPPVSSFVADIARYTEVANNVQKEETVT-NIQFVLLDCSHLK 1021
D+F+ H Y+++ + +I +Y ++ +Q T + + C L
Sbjct: 510 -----DNFLAENHSYEKI-------IDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELI 557
Query: 1022 FSLVQHCNEWQNKF-ATLLREMAAGRLLELHTYLKENAEKI-----SRPPQTLEELGVSL 1075
+LV+ + K A + R+ E++T L + E+I S PP T E + +
Sbjct: 558 RALVKRADIICGKLLAKMFRDHQ-----EVNTRLCDEFERIAEKALSTPPNTAELMEMKA 612
Query: 1076 QLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSK 1135
+ D+ +E ++ A L +Y V + + + +S+ + + + +
Sbjct: 613 YIQKVEVTDMIELEQRLVDSKNCLAFLIEY-VNFSPADMRLNNSVFQWYGRMGEIFEEHR 671
Query: 1136 QMLKKHKEKFKTGLIHSADDFKKKAHTLL---EDFEFKGHFTSNVGYMSALDQITQVRAM 1192
+++K+ E+++ GL + F ++ + E+F G Y+ + +
Sbjct: 672 KIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDL 731
Query: 1193 LMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRF 1252
E+ N+ G P K +Q+ L+ +++E A ++ N+ W G +
Sbjct: 732 AADKIEQFNAEEEAFGWLPSVYPQRKKIQD---GLNPYLRLYETAVEFSSNYRAWTEGPY 788
Query: 1253 LILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIET--TRSKIEQFKRTMPLISDLRNPA 1310
+ + +E +R L KL K + D + + T RSK+E FK+ +PLI + NP
Sbjct: 789 HKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPG 848
Query: 1311 LRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQN 1370
LR RHW+ + + Q S+ T+ +++ ++ ++++ IS +A+KE ++E A++
Sbjct: 849 LRPRHWEAMSAIVGYPL-QPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEK 907
Query: 1371 IAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWE 1430
+ WD + I Y++ G L +E+ L+D+ + TM+ S F+K +EK + WE
Sbjct: 908 MITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWE 967
Query: 1431 RCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKD 1490
L L+ E+++ L VQ W+YLE IF DI Q+P E F V+ W+ IM + +D
Sbjct: 968 GKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQD 1027
Query: 1491 NNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSR 1550
+ L +L+ L + N +LE I K L+ YLE KR FPRF+FLSND+LLEIL +++
Sbjct: 1028 KHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETK 1087
Query: 1551 NPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFL---EGPVE 1607
+P VQPHLKKCF+ I + + + M S +GE ++ + + G VE
Sbjct: 1088 DPTRVQPHLKKCFEGIAKVEFTET------LDITHMKSSEGEVVELIEIISTAKARGQVE 1141
Query: 1608 SWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCL 1667
WL ++E+ M ++ + + A K+ +R WV++W GQ V+ SQI WT +V +
Sbjct: 1142 KWLVELERVMINSIHKVTGDATFAYTKY--ERINWVRDWPGQTVLCVSQIFWTKEV-QTA 1198
Query: 1668 LTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLY 1727
+ +A ++ LK + I+ +RG L+ R+ + ALV +++HARDVL L
Sbjct: 1199 IPMGIKALEQYLKTCNRQIDDIVT----LVRGKLSMQNRVTLGALVVLDVHARDVLSSLV 1254
Query: 1728 KSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYM 1787
K + D + F+WLSQLR+YW+++ + N +Y YEYLGNS RLVITPLTDRCY
Sbjct: 1255 KKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYR 1312
Query: 1788 TLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQ 1847
TL ALHLH GG+P+GPAGTGKTET KDL KA+ +V NCS+GLDY ++G+ + GL
Sbjct: 1313 TLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLS 1372
Query: 1848 TGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNP 1907
GAW CFDEFNRI++EVLSVVA QIL I + AG F+G E+ L +C +FITMNP
Sbjct: 1373 CGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNP 1432
Query: 1908 GYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQL 1967
GYAGR+ELP+NLK++FR +AM+VPD +IAEI+L+ GF + L+ K+ Y L +QL
Sbjct: 1433 GYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQL 1492
Query: 1968 SRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIV 2027
S Q HYD+G+RA+ S+L AG + P+ +E +LL S+ D+N+ K S D PLF I
Sbjct: 1493 SSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGIT 1552
Query: 2028 QDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTG 2087
DLFP ++LP DY L ++ M LQ T F K+ Q+YE RH MIVG
Sbjct: 1553 SDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPF 1612
Query: 2088 SGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILS 2147
GKT+++R+L +L+ +C G N V+ LNPK++++G+LYG++D ++EW+DG+L+
Sbjct: 1613 GGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLA 1672
Query: 2148 SVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFE 2207
R + PD KW++FDGPVD +WIENMN+V+DDNK L L++GE I M Q++L+FE
Sbjct: 1673 VSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFE 1732
Query: 2208 VEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQR-----MFEKLIN 2262
DL +ASPATVSRCGM+Y + LGW+P + SW+ P A V +Q+ +F++++
Sbjct: 1733 PMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLP-ASVSVIQKEFIMGLFDRMVP 1791
Query: 2263 KMLAFKKDNCKELVPLPEYSGITSLCKLYSALA---TPENGVNPADGENYVTMVEMTFVF 2319
+ F + + KEL P + + + SL L E + + +++E F+F
Sbjct: 1792 VSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLF 1851
Query: 2320 SMIWSVCASVDEEGRKRIDSYLREIEGS---------------------------FPNKD 2352
S+IWSV AS ++ R + + LRE+ S FP K
Sbjct: 1852 SLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKG 1911
Query: 2353 TVYEY-FVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNP 2411
T+Y+Y FV I W + KL ++ P + F +I+VPT+DT+RY+ L+ L +Q P
Sbjct: 1912 TIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKP 1971
Query: 2412 ILLVGPVGTGKT-SIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVY 2470
+ VGP GTGK+ I +L L + L++N SAQTT+ Q+I+ S+++KR KGV+
Sbjct: 1972 SIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVF 2031
Query: 2471 VPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAA 2530
P GK M+ F+DD+NMPA++++G+QPP+EL+R W+D+ WYD ++ + ++ +M A
Sbjct: 2032 GPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCA 2091
Query: 2531 MGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQ---DFEEEVKPIGNV 2587
MGPPGGGR ++PR FNII + + + IF ++ L+ F +E +
Sbjct: 2092 MGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQ 2151
Query: 2588 VTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHE 2647
+ T+ +Y ++ LPTP K HYLFNLRD S+V QG+ + + +T I RLW+HE
Sbjct: 2152 IVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHE 2211
Query: 2648 CFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHL-------------CPSKRPPIFG 2694
RV+ DRL+D D + I + L ++ FH L R +F
Sbjct: 2212 VLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFC 2271
Query: 2695 DF---LKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVI 2751
DF +E Y ++ D+ L+ ++E L EYN + S PM LVLFR AIEHI+RI R++
Sbjct: 2272 DFHDPKREDTNYREIADVDNLRMIVEIHLEEYN-NISKKPMNLVLFRFAIEHISRISRIL 2330
Query: 2752 GQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVE 2811
QPR + LLVG+GGSGRQS+ RLA+ + DY+ FQ+E++K Y E+ +D+K + R+
Sbjct: 2331 KQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEG 2390
Query: 2812 LKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEI--QSHIIDQAR--VEQV 2867
F+F DTQI +ESFLED++N+L++GE+PNL+ DE +EI + +D+ R +Q
Sbjct: 2391 EMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQT 2450
Query: 2868 PESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALL 2927
S +LF I+ ++ LH+VL +SP+GD FRN +R++PALVNC TI+WF WP++AL
Sbjct: 2451 DGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQ 2510
Query: 2928 EVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLS 2987
VA + L +++ E I + + H S S+ +EL+R+NYVTPT YLEL+S
Sbjct: 2511 AVASRFLEEIEM--SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELIS 2568
Query: 2988 GYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLV 3047
+K LL +KR E++ + GL K+D +V M +ELE ++ K+ +E ++
Sbjct: 2569 TFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMI 2628
Query: 3048 IIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNK 3107
+I ++ E + +K V A+ + + +A+ D DL ALP LE A+ AL++L
Sbjct: 2629 MIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTA 2688
Query: 3108 KDIGEIKSYGRPPAQVEIVMQAVMILRG------NEPT---------WAEAKRQLGEQNF 3152
+DI +KS PPA V++VM+A+ IL+G +PT W AKR LG+ F
Sbjct: 2689 QDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRF 2748
Query: 3153 IKSLINFDKDNISDKVLKKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYR 3211
++SL +DKDNI + I Y PDF P+ I S AA+ LC WV AM+ Y ++ +
Sbjct: 2749 LQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAK 2808
Query: 3212 VVEPKRIRMNAALAQ-------LREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEE 3264
+V PK+I++ AA + LR+KQAAL E Q+KL + + LE+ K+ +K +
Sbjct: 2809 IVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQ-------KKAD 2861
Query: 3265 LRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPF 3324
L + + KLERA L+ GL GEK RW T L + L GD L+++ ++Y+G F
Sbjct: 2862 LENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAF 2921
Query: 3325 LTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGII 3384
+ YR + W +PCS ++ L +R WNI GLPSD+FS +NGII
Sbjct: 2922 TSTYRQNQTKE-WTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGII 2980
Query: 3385 VTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQ 3444
+ RW LMIDPQ+QA KWIKNME L +I L DY+R LE+ I FG PVLL+NV
Sbjct: 2981 IMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVG 3040
Query: 3445 EYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTI 3504
E LDP L P+L K + GG +R+GD +EY +FRFYITTKL NPHY PETS K T+
Sbjct: 3041 EELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTL 3100
Query: 3505 VNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATG 3564
+NF + +G++ QLLGIVV +ERP+LEE+K +L++ A KR+LKE+ED+IL +L+ + G
Sbjct: 3101 LNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEG 3160
Query: 3565 SLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDM 3624
++L+D + L +SK A E++++ E +E TE D R YRP A +SILFF L D+
Sbjct: 3161 NILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADL 3220
Query: 3625 GCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKL 3684
I+PMYQ+SL +I+LFILSI+ S +S L R+ L D+ TY++Y CR+LFE+ KL
Sbjct: 3221 ANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKL 3280
Query: 3685 LFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKL 3744
LFSF + +L +N E+ F L GG+ LD N C +WL WD I LD L
Sbjct: 3281 LFSFCLTINLLLHERAINKAEWRFLLTGGIGLD--NPYANLC-TWLPQKSWDEICRLDDL 3337
Query: 3745 TNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCV 3804
F + F + W Y + P + P EWE+ NE QRMLI+R LR D+V +
Sbjct: 3338 PAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPML 3397
Query: 3805 TSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM-AQR 3863
FII LG FIEPP ++ DS +PL+F+LSPG DP +ALL+ A+ G +
Sbjct: 3398 QEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSK 3457
Query: 3864 FHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFR 3923
+LSLGQGQ PIA ++L + V +G WV L NCHL+ SWMP L+K+ E+L E HP FR
Sbjct: 3458 LSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFR 3517
Query: 3924 LWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQL--MSEPQ-FSRCSKPAKYKK 3980
+WL+S P P+FP+S+LQ +KMT E PKGL+AN+ R Y + +S+P+ F C KP ++KK
Sbjct: 3518 MWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKK 3577
Query: 3981 LLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLI 4040
LL+ LCFFH+++ ER+KF LGWNI Y FN++D +S L ++L++YEE P++AL+Y+
Sbjct: 3578 LLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMT 3637
Query: 4041 AGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYIS 4100
NYGG VTDDWDRR L + +N +F + + ++ + YF+P G SY EY
Sbjct: 3638 GECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTK 3697
Query: 4101 LLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAAD 4160
LP PE FG + NAD+ +E Q LFD +L Q + AG ++ +E V E+A+D
Sbjct: 3698 TLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSR--SAGAGAKSSDEVVNEVASD 3755
Query: 4161 VKQKIPEMIDYEGTQKLLALD-PSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIV 4219
+ K+P D E + +N VL+QE+ R+N L++TI S +++K I+GL V
Sbjct: 3756 ILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAV 3815
Query: 4220 MSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFW 4278
MST LEE+ + I + +P +W GK+YPS KPL ++ D R++ + W PP +FW
Sbjct: 3816 MSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQW-YEVGPPPVFW 3874
Query: 4279 LSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEG 4338
LSGF F FLT Q+ AR+ + +D L +++ V ++D +PP+DGV++ GL+L+G
Sbjct: 3875 LSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEV--MEDKEYKHPPEDGVFIHGLFLDG 3932
Query: 4339 AGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSD 4394
A W+RK L E+ P L +P + +P + + Y P Y R G +
Sbjct: 3933 ASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGH 3992
Query: 4395 RASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS 4427
+FVI + L S +HWI RG ALL L+S
Sbjct: 3993 STNFVIAMTLPSD-QPKEHWIGRGVALLCQLNS 4024
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2437 bits (6315), Expect = 0.0
Identities = 1481/4378 (33%), Positives = 2359/4378 (53%), Gaps = 246/4378 (5%)
Query: 193 IRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHW 252
IR+ F ++ KF + + T +LEG L +P ++ + + D E V LE +I+W
Sbjct: 196 IRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAADPETVDILEQCVINW 255
Query: 253 TRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKS 312
QI + AQ +T + GPL EIEFWR R LS + +Q V+ V ++ + S
Sbjct: 256 LNQISTAVEAQ-LKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDS 314
Query: 313 SYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDIS-SKLPKLISLIRII 371
+A + ++ +A N+ FLS ++ ++ + + +P ++S +R++
Sbjct: 315 MLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMV 374
Query: 372 WVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQITRNLLEIEDIF 431
W+ S HYN ER+ L ++ WE ++ ++ + +F
Sbjct: 375 WIISRHYNKDERMIPLMERIA--------WEIAER--------------VCRVVNLRTLF 412
Query: 432 HKNLHTLRAVRGGILDVKNTC--WHEDYNKFRAGI-------------KDLEVMTQNLIT 476
+N + + L+ +NT W + Y RA I K L T + T
Sbjct: 413 KENR---ASAQSKTLEARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMAT 469
Query: 477 SAFELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVD---------------------- 514
+ +D+ + +L+ F+ + E T D K +D
Sbjct: 470 ----ICQDLSDVLQILEEFYNIFGPELKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFS 525
Query: 515 -------LYML--FNSELAL--VNR--ERNKKWPDLEPYVAQYSGKARWVHILRRRIDRV 561
Y++ F E+ + +N+ +N + P L +G W L RI
Sbjct: 526 IKSSQFWKYVMDEFKIEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHT 585
Query: 562 MTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRI 621
+ + G+E Y ++ + + E + +++W ++ + LL
Sbjct: 586 ILRFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTK 645
Query: 622 SQ---------EKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILR 672
S E+ + +NF +L + E Y E+L F P NVA + +
Sbjct: 646 SSIATEEPSTLERGAVFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYT 705
Query: 673 ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732
+ + Y+ +I L+ E L K+ + L + G K+L+W G + IT C+
Sbjct: 706 AGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDY-ITGCKQ 764
Query: 733 HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDL----EFEEDQREHRAAV 788
K + +V++ + I R + L + + +L EF E RA+
Sbjct: 765 AIGKFESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASD 824
Query: 789 QQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELS 848
++ + + ++T + + + Y ++ + + L + +L +
Sbjct: 825 VDHMVRWYLAIGPLLTKVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFN 884
Query: 849 KAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFC 908
I G+ PLF IL + ++ P N+I F +
Sbjct: 885 SLILGNV-----PLFHTETIL------TAPEIILHPN-------TNEIDKMCFHCVRNCV 926
Query: 909 HLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQN-------------- 954
+ R ++ I+ ++ E+ + + + ++ N +++
Sbjct: 927 EITKHFV-RWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILIN 985
Query: 955 ---YLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQ 1011
YL+ W YR +W+++K + ++ PP ++ + Y+++A V + + +
Sbjct: 986 LMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMRHPLIKDEH 1045
Query: 1012 FVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEEL 1071
+ L HL ++ ++ W LL E A L LH ++ A+ + + P TLE+L
Sbjct: 1046 CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDL 1105
Query: 1072 GVSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTL 1131
L + ++ +E + + E++ + Y + D+ E++D + W
Sbjct: 1106 KFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDS 1165
Query: 1132 LDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRA 1191
++ + L K F +++ + + F +G +VG LD+ ++
Sbjct: 1166 VNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEG--PGSVG--DDLDKGVELLG 1221
Query: 1192 ML---MAMREEENSLRANLG-IFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEW 1247
+ +A E+ AN +F + +L ++KE+ L+ I+E+ + EW
Sbjct: 1222 VYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEW 1281
Query: 1248 KTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLR 1307
++ L + ++ G R L KL + R + +K++ FK ++PL+ DL+
Sbjct: 1282 SQTLWINLNVQILQEGIEGFLRALRKLPRPV--RGLSVTYYLEAKMKAFKDSIPLLLDLK 1339
Query: 1308 NPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVA 1367
N ALR+RHW ++ ++ F+ +E+FTLE + + + +H + + EI +A KE+AIE A
Sbjct: 1340 NEALRDRHWKELMEKTSVFFEM-TETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKA 1398
Query: 1368 LQNIAKTWDVTQLDIVPYKDKGHHR---LRGTEEVFQALEDNQVALSTMKASRFVKAFEK 1424
++ I TW+ + +V Y R L +E+ Q+L+DN L ++ SRFV F +
Sbjct: 1399 VKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQ 1458
Query: 1425 DVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIM 1484
V WE+ LSLI EVIE+ + VQR+WMYLE+IF+G DIR QLP E+ FD ++ +K IM
Sbjct: 1459 TVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIM 1518
Query: 1485 DRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLE 1544
KD R P L L ++ LE QKSL+ YL++KR+ FPRF+F+S+D+LL
Sbjct: 1519 GETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLS 1578
Query: 1545 ILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEG 1604
ILG S +P VQ H+ K +DNI LR G S + M S +GE ++F + EG
Sbjct: 1579 ILGSS-DPLCVQEHMIKMYDNIASLRFND--GDSGEKLVSAMISAEGEVMEFRKILRAEG 1635
Query: 1605 PVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDK--WVKEWAGQVVITASQIQWTAD 1662
VE W+ V MR T R + + A+ ++ R + W+ + G VV+ ASQ+ WT +
Sbjct: 1636 RVEDWMTAVLNEMRRTNRLITKE---AIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWE 1692
Query: 1663 VTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDV 1722
V A ++ +K+ +K + +++ I L+K R K ++ I++HARD+
Sbjct: 1693 VEDVFHKA-QKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDI 1751
Query: 1723 LEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLT 1782
++ + +++ FDW SQLRFYW+++ D+ IRQ F Y YEY+G +GRLVITPLT
Sbjct: 1752 VDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLT 1811
Query: 1783 DRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMY 1842
DR Y+TLT AL ++ GG+P GPAGTGKTET KDL KALG+ +V NC EG+DY+++G+++
Sbjct: 1812 DRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIF 1871
Query: 1843 SGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIF 1902
SGLAQ GAWGCFDEFNRI+ VLSV++ QI I +AL LT F F+G EI+L GIF
Sbjct: 1872 SGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIF 1931
Query: 1903 ITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSL 1962
ITMNPGYAGRTELPE++K++FRP+ ++VPD I EI+LF EGF K LAKK+ LY L
Sbjct: 1932 ITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKL 1991
Query: 1963 AVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPL 2022
A +QLS+Q HYDFGLRAL S+L AG+ +R DL ++ VL+ ++RDMN+ K D PL
Sbjct: 1992 AREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPL 2051
Query: 2023 FNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMI 2082
F ++ DLFP ++ P + Y + VEQ + + G P + KV Q++ET +RH+TM+
Sbjct: 2052 FLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMV 2111
Query: 2083 VGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWT 2142
VG T GK+ +++LC+A + + LNPKA+S+ ELYG D +T +WT
Sbjct: 2112 VGPTRGGKSVV-------INTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRDWT 2164
Query: 2143 DGILSSVMRTACAD-EKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQ 2201
DG+LS++ R +K + K+ILFDG VD LW+ENMNSVMDDN++LTL NGERI +
Sbjct: 2165 DGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAH 2224
Query: 2202 VSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRP-KAEVEPLQRMFEKL 2260
+LLFEV DL ASPATVSRCGMVY D +L ++PY + W+ + P K E L +FEK
Sbjct: 2225 CALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKY 2284
Query: 2261 INKMLAF---------KKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPADGENYVT 2311
+ ++ + + K +VP + + +T L K+ AL E + D
Sbjct: 2285 VPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALL--EGEIEDLD------ 2336
Query: 2312 MVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI--------EGSFPNKD-------TVYE 2356
++E F+ ++ S+ AS+ E+GR + D Y++ + EG + N T+Y+
Sbjct: 2337 LLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYD 2396
Query: 2357 YFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVG 2416
+ D K W + +P+ + + P F I+V TVDT R +++ +V + P++ VG
Sbjct: 2397 FHFDNKRNQWVPWSKLVPE-YIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455
Query: 2417 PVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGK 2476
GT KT+ Q+ L++L VL+VN S++TTS ++Q +E+ VEKRTK Y P GK
Sbjct: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515
Query: 2477 SMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQ-TIKYIREMFLMAAMGPPG 2535
++ FMDD+NMP D +G+Q P+ L++L ++ G+ YDR K+ K IR++ +AAMG G
Sbjct: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575
Query: 2536 GGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDM 2595
GGR + PR S F++ N+ FP++ + I+ +++ F E + + +T TL +
Sbjct: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLAL 2635
Query: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655
Y +VQ PTP+K HY+FNLRD+S+VF G++ N + T + + R+W +EC RVF DR
Sbjct: 2636 YKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDR 2695
Query: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPS-----KRPPIFGDFLK-----EPKVYED 2705
L+ D + ++ +GS L H + P +FGDF EP++YED
Sbjct: 2696 LISETDKQ----LVQQHIGS---LVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYED 2748
Query: 2706 LTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGG 2765
+ D K + + L EYN S + M LVLF +A+EH+TR+ R+I RG+ LLVG+GG
Sbjct: 2749 IQDYEAAKALFQEILEEYNESNT--KMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGG 2806
Query: 2766 SGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIA 2825
SG+QSL+RLA+ F+I +++ Y + FR+D+K LY + G+E K F+F D +A
Sbjct: 2807 SGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVA 2866
Query: 2826 DESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNN 2885
+E FLE INN+L+SG VP L+ +E E I S I +A + + + +S++ Y + + NN
Sbjct: 2867 EEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANN 2926
Query: 2886 LHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI 2945
LHIVL +SP+GD R W R +P +VN T I+WF WP +AL VA+ L + ENI
Sbjct: 2927 LHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENI 2986
Query: 2946 HRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQAN 3005
V + V +H SV YSQ+ L +LRR NYVTP YL+ ++ Y KLL EK Q +AQ
Sbjct: 2987 ENVVKHV-VLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCK 3045
Query: 3006 KLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTA 3065
+L GL K+ E ++ ++ +L + K +AE CE L I A+E++K
Sbjct: 3046 RLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEE 3105
Query: 3066 NSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEI 3125
+ +I + A+ L E +P LE A L+ L+K D+ EI+S+ +PP QV+
Sbjct: 3106 KAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQT 3165
Query: 3126 VMQAVMILRG-NEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPD 3184
V + ++I++G E W AK + + NF++SL+ D D+I+ +K I + +
Sbjct: 3166 VCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTE 3225
Query: 3185 IIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREV 3244
+ VS A + +V A+ Y ++R ++PKR ++ + L Q +L +
Sbjct: 3226 EMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAI 3285
Query: 3245 AEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDL 3304
++LE L +Y+ + +K++L++++E ME +L A L+SGL E RW + L
Sbjct: 3286 QKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRR 3345
Query: 3305 GYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKV 3364
L+GDCLL AAFLSY G F +RDE+VN+IW I E ++P S F +++ L + ++
Sbjct: 3346 VKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEI 3405
Query: 3365 RDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDY 3424
W QGLP D S +NGI+ TR +R+ L IDPQ QAL WIK E L++ D+
Sbjct: 3406 SRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDF 3465
Query: 3425 LRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFY 3484
L+ LE +I +G P L ++V EY+DP ++ +L K++ GR + +GDKEV+Y++NFR Y
Sbjct: 3466 LKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLY 3525
Query: 3485 ITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAG 3544
+ TKL+NP YSP K ++N+ V +GLE QLL ++V ER ELEEQ++ L+ +
Sbjct: 3526 LNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSEN 3585
Query: 3545 KRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAR 3604
K LK+LED +LR L +TG++LD+V LV+TL +K ATEV+E+L+ +E T ++ D R
Sbjct: 3586 KNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLR 3645
Query: 3605 EAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLND 3664
+ YRP A+R +ILFFVL++M ++ MYQ+SL A++ +F LS+ KS + L R+ + D
Sbjct: 3646 DGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMD 3705
Query: 3665 YHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDN 3724
T+++Y + C LFERHKLLFSF+M KI + G++ +E +FFL+G + L++ +
Sbjct: 3706 TLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEK-SKRKK 3764
Query: 3725 PCSSWLADAYWDNITELDKL--TNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENA 3782
PC +WL+D W++I L ++ NF L + E W WY + E+ +P ++N
Sbjct: 3765 PC-AWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNN 3823
Query: 3783 CNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILS 3842
Q++LI+R R DRV VT ++ +G ++++PP+++ +++ E STP SP+VFILS
Sbjct: 3824 ITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILS 3883
Query: 3843 PGVDPTSALLQLAEHMGM-AQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLS 3901
PG DP + L++LAE G R L++GQGQ +A +LL V +G W+ L NCHL +
Sbjct: 3884 PGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVK 3943
Query: 3902 WMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLY 3961
W+ +L+K +E ++ PHP FRLWL++ P FPI ILQ S+K+ TEPP GLK NM Y
Sbjct: 3944 WLKDLEKSLE--RITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATY 4001
Query: 3962 QLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLL 4021
+S +C PA +K L++ L FFH+V+ ER+KF ++GWN+ Y FN+SDF+V +L
Sbjct: 4002 FKISHEMLDQCPHPA-FKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEIL 4060
Query: 4022 SLYLDEY-----EETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLST--P 4074
+ YL + PW +LKYLI + YGG D +DRR+LT Y+++Y D T P
Sbjct: 4061 NTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQP 4120
Query: 4075 FHRLSALET-YFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTL 4133
FH E Y IP + E I LP + PE FG HPNA++ A+ ++ L
Sbjct: 4121 FHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHL 4180
Query: 4134 LSLQPQITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEI 4193
L LQPQ T + G +R++ + ++A +++ K+P++ D + +K L SP +VVLLQE+
Sbjct: 4181 LELQPQ-TGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQEL 4239
Query: 4194 QRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYP-SQKPLAA 4252
+R+N L+ + SL +L++ + G + MS L+++ +F H+P +W + P + K L
Sbjct: 4240 ERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGN 4299
Query: 4253 WTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFI 4312
W R Q+ LW + + P V+ WLSG P +LTA++Q++ R+N +D +
Sbjct: 4300 WMVYFLRRFSQYMLWVTESEPSVM-WLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQ 4358
Query: 4313 VSTVDDSNLVYP-PKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESR 4371
V+ D++ V G +V GLYLEGA WD + CL++++P LV +P + P E+
Sbjct: 4359 VTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAH 4418
Query: 4372 KKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTP---DHWIKRGTALLMSLD 4426
+ + + P Y S R + +G+ + T HW+ +G L ++ D
Sbjct: 4419 RLKLQNTFRTPVY-----TTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTLNSD 4471
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 2425 bits (6285), Expect = 0.0
Identities = 1361/3569 (38%), Positives = 2063/3569 (57%), Gaps = 154/3569 (4%)
Query: 955 YLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVL 1014
YL + Y ++ + + I + + N + FV I + N + +
Sbjct: 606 YLNVYKKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASMNITVPLAMFC 665
Query: 1015 LDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVS 1074
LD + L L + ++ ++ + A+K+S P +EL
Sbjct: 666 LDATALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKEL--- 722
Query: 1075 LQLVDALKHDLA----NVETQIPPIHEQFAILEKY-EVPVEDSVLEMLDSLNGEWVVFQQ 1129
+ L++ LK A + Q+ E+ L Y ++P + + ++ D+
Sbjct: 723 VSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQ--IEDIFDN---------- 770
Query: 1130 TLLDSKQMLKKHKEKFKTGLIHSADDFKKKA---HTLLEDFEFKGHFTS-----NVGYMS 1181
S+ +L +++ + LI +F+ + H LE F + T+ NV ++
Sbjct: 771 ----SRNLLLHKRDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLN 826
Query: 1182 ALDQ-ITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDW 1240
L + + + A + +EE L + + LQ + K +Q+W A ++
Sbjct: 827 ELSKNLNRAFAEFELINKEEELLEKEKSTYPL-------LQAMLKNKVPYEQLWSTAYEF 879
Query: 1241 EENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKD--RNWEIIETTRSKIEQFKR 1298
EW G +L E + ++R KL K D + E + KI++FK+
Sbjct: 880 SIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQ 939
Query: 1299 TMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASA 1358
+P++S NP +++RHW Q+ + + E + +E+ L ++E G + VEK+ I A+A
Sbjct: 940 YIPILSISCNPGMKDRHWQQISEIVGYEI-KPTETTCLSNMLEFGFGKFVEKLEPIGAAA 998
Query: 1359 TKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRF 1418
+KE ++E L + W V Y+D + L +++ L+D+ + TM S F
Sbjct: 999 SKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPF 1058
Query: 1419 VKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNS 1478
+K E + WE L I + ++ L Q W+YLE IF EDI Q+P E F V+S
Sbjct: 1059 IKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDS 1118
Query: 1479 NWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLS 1538
WK++M + KDN L + P + + L E N +LEDIQK L+ YLE KR FPRF+FLS
Sbjct: 1119 YWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLS 1178
Query: 1539 NDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLH 1598
ND+LLEIL ++++P VQPHLKKCF+ I L + E VGM S + E + F+
Sbjct: 1179 NDELLEILSETKDPLRVQPHLKKCFEGIAKLEF------TDNLEIVGMISSEKETVPFIQ 1232
Query: 1599 SVF---LEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLN-KRDKWVKEWAGQVVITA 1654
++ +G VE WL VEQ M ++R+++ L + ++ R+ WV +W GQVVI
Sbjct: 1233 KIYPANAKGMVEKWLQQVEQMMLASMREVIG---LGIEAYVKVPRNHWVLQWPGQVVICV 1289
Query: 1655 SQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVT 1714
S I WT +V++ L A+ +L +KK+ I + + +RG L+ RL + AL
Sbjct: 1290 SSIFWTQEVSQAL------AENTLLDFLKKSNDQIA-QIVQLVRGKLSSGARLTLGALTV 1342
Query: 1715 IEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSG 1774
I++HARDV+ KL + + D+N F W+SQLR+YW D ++ T+ Y YEYLGNS
Sbjct: 1343 IDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWVAK--DVQVQIITTEALYGYEYLGNSP 1400
Query: 1775 RLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLD 1834
RLVITPLTDRCY TL AL L+ GG+P+GPAGTGKTET KDL KAL +V NCS+GLD
Sbjct: 1401 RLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLD 1460
Query: 1835 YKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEIN 1894
YK+MG+ + GLAQ GAW CFDEFNRI +EVLSVVA QIL I A+ L F F+G E++
Sbjct: 1461 YKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELS 1520
Query: 1895 LVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAK 1954
L +C +FITMNPGYAGR ELP+NLK++FR +AM+VPD LI EI L+ GF + + LA+
Sbjct: 1521 LNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQ 1580
Query: 1955 KVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAK 2014
K+ Y L +QLS Q HYD+G+RA+ S+L AG + P+ + +LL ++ D+N+AK
Sbjct: 1581 KIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAK 1640
Query: 2015 LTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETK 2074
+ D PLF I+ DLFP + LP DY + + I+ M LQ P+ + K+ Q+YE
Sbjct: 1641 FLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMM 1700
Query: 2075 NSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEY 2134
RH MIVG GKT+++++L A+L L A V +NPKA+++G+LYG +
Sbjct: 1701 LVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCF 1760
Query: 2135 DLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGE 2194
D ++EW DG+L++ R + D KWI+FDGPVD +WIENMN+V+DDNK L L++GE
Sbjct: 1761 DQVSHEWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGE 1820
Query: 2195 RIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRP----KAEV 2250
I M ++SL+FE DL ASPATVSRCGM+Y + LGWKP S+++ P K
Sbjct: 1821 IIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHK 1880
Query: 2251 EPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSAL-----ATPENGVNPAD 2305
E + MF L+ L F + +CK +V S+ +LYS+L A E + +
Sbjct: 1881 ELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGE 1940
Query: 2306 G---ENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI------------------ 2344
G + ++ F+FS++W+V +++ + RK+ D + R +
Sbjct: 1941 GLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTK 2000
Query: 2345 EGSFPNKDTVYE-YFVDPKIRSWTSFEDKLPK-SWRYPPNAPFYKIMVPTVDTVRYNYLV 2402
FP + ++Y+ YF+ W ++ + K + P A ++++PT++T R ++ +
Sbjct: 2001 NNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFL 2060
Query: 2403 SSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRV 2462
+ + ++ P+L VGP GTGK++I + L LP + + +N SA+T++N Q II S++
Sbjct: 2061 KTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKL 2120
Query: 2463 EKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYI 2522
++R KG++ P GK + F+DDLNMPAK+++G+QPP+EL+R WID+G+W+D+ T I
Sbjct: 2121 DRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDI 2180
Query: 2523 REMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL-QDFEEEV 2581
+M L+ AMGPPGGGR I+ R NII++ + +IF ++++ + F+
Sbjct: 2181 VDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKGFDVMF 2240
Query: 2582 KPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSIT 2641
G ++ +AT +Y V+ FLPTP+K HY+FNLRD S+V QG+L
Sbjct: 2241 LRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCI 2300
Query: 2642 RLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFH----HLCPSK-------RP 2690
RLWIHE +RVF DRL+D D + F ++ + + F T HL P+ R
Sbjct: 2301 RLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRS 2360
Query: 2691 PIFGDFLK---EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRI 2747
FGD+ K + K+Y+++TDL L VME L E+N + S PM LV+FR AIEHI+RI
Sbjct: 2361 LFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFN-NISKAPMSLVMFRFAIEHISRI 2419
Query: 2748 VRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQ 2807
RV+ Q +G++LLVGIGGSGRQS A+L++ + Y +QIE+TK+Y ++R+D+K++ Q
Sbjct: 2420 CRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQ 2479
Query: 2808 AGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARV--E 2865
GV K+T F+F D QI DESF+EDIN +L++G+VPN++ DE +I + AR E
Sbjct: 2480 VGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGE 2539
Query: 2866 QVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEA 2925
+V + S++ + IERV N + L +SP+GD FRN +R +P+L+NC TI+WF WP +A
Sbjct: 2540 KVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDA 2599
Query: 2926 LLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLEL 2985
L VA K L V+L +NI +V + SV + S +LRRHNYVTPT YLEL
Sbjct: 2600 LELVANKFLEDVEL--DDNIRVEVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLEL 2657
Query: 2986 LSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEY 3045
+ +K LL KRQE+ N+ TGL K+D +V VM EL + ++ ++ +
Sbjct: 2658 ILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKM 2717
Query: 3046 LVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESL 3105
+V I + READ ++ V A+ ++ V Q + + + DL EA+PALE A+ AL++L
Sbjct: 2718 MVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTL 2777
Query: 3106 NKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPT---------------WAEAKRQLGEQ 3150
N DI +KS PP V++VM+++ I++G +P W +K+ LG+
Sbjct: 2778 NPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDL 2837
Query: 3151 NFIKSLINFDKDNISDKVLKKI-GAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRL 3209
F++SL +DKDNI +K+I + P+FQP +I VS A + LC WVRAME+Y R+
Sbjct: 2838 KFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRV 2897
Query: 3210 YRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKS 3269
+VV PKR R+ A +L + L + + +L+ V ++L+ L ++E +K++L +
Sbjct: 2898 AKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENI 2957
Query: 3270 EEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYR 3329
E KL RA L+SGL GEK RW E + L L GD LL++ ++Y+G F +YR
Sbjct: 2958 EICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYR 3017
Query: 3330 DEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGN 3389
+ NQ W+ + + +P F++ + L +P K+R W I GLP D+FS +NGIIV+
Sbjct: 3018 VQCQNQ-WLAECKDKVIPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSR 3076
Query: 3390 RWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDP 3449
RWALMIDP QA KWIKNME L +I S+Y+R+LE+A+ G PVL++N+ E LD
Sbjct: 3077 RWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDA 3136
Query: 3450 TLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAV 3509
++ P+L K+ + G MR+G+ +EY+ +F+ YITT+L NPHY PE + K ++NF +
Sbjct: 3137 SIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMI 3196
Query: 3510 KEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDD 3569
GL+ QLLGIV KE+PELEE+K+ L++ A K+ LKE+ED+IL +L+ + G++L+D
Sbjct: 3197 TPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILED 3256
Query: 3570 VQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDP 3629
+ L +SK+ + E++E+ + + TE D R Y+P A ++ +FF ++D+ I+P
Sbjct: 3257 ETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEP 3316
Query: 3630 MYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFH 3689
MYQ+SL +I+L++ S+ S +S +L RI Y+ D+ T ++Y CR+LFE+ KLLFS
Sbjct: 3317 MYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLL 3376
Query: 3690 MCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHG 3749
+ I++ ++ + + F L GG+ LD NP WL++ W I L HG
Sbjct: 3377 LTIGIMKQKKEITEEVWYFLLTGGIALD--NPYPNPAPQWLSEKAWAEIVRASALPKLHG 3434
Query: 3750 LMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFII 3809
LM EQ +W L Y +A P + LPG W+ + +++M+I+R LR D++ V FI
Sbjct: 3435 LMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFS-QGLEKMVILRCLRPDKMVPAVREFIA 3493
Query: 3810 TNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM-AQRFHALS 3868
++G +IE P +++ DS+ +PL+F+LSP DP + LL+ A+ +GM R +S
Sbjct: 3494 EHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTIS 3553
Query: 3869 LGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQV-EDPHPSFRLWLS 3927
LGQGQ PIAA+++ + G WV L NCHL+ SWMP L+K+ E++ V E + FRLWL+
Sbjct: 3554 LGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLT 3613
Query: 3928 SIPHPDFPISILQVSIKMTTEPPKGLKANMTRLY--QLMSEPQ-FSRCSKPAKYKKLLFS 3984
S P FP+SILQ IKMT EPPKGL+AN+ R Y +S+P F C+K ++K+LF
Sbjct: 3614 SYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFG 3673
Query: 3985 LCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGIN 4044
LCFFH+V+ ER+ F LGWNI Y FN+SD +S + ++L++Y+E P+DAL YL N
Sbjct: 3674 LCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECN 3733
Query: 4045 YGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPG 4104
YGG VTDD DRRLL + ++ ++C + + ++ L+ +TY+IP GS SY +Y+ LP
Sbjct: 3734 YGGRVTDDKDRRLLLSLLSMFYC-KEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPI 3792
Query: 4105 MDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAADVKQK 4164
PE FG H NAD+ E LF+ +L P+ + G++ +E V ELA D+ K
Sbjct: 3793 TAHPEVFGLHENADITKDNQETNQLFEGVLLTLPR--QSGGSGKSPQEVVEELAQDILSK 3850
Query: 4165 IPEMIDYEGTQKLL-ALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTS 4223
+P D E KL + +N VL QE+ R+N L + + SL +L + I+G ++MS+
Sbjct: 3851 LPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSE 3910
Query: 4224 LEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGF 4282
LEE+FN + VP +W K+YPS KPL + DL R+ F+ W + PPV+FW+SGF
Sbjct: 3911 LEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKG-PPVVFWISGF 3969
Query: 4283 TFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWD 4342
F FLT V Q+ AR+ + +D + +EF V T ++ + P+DG +++GL+LEGA WD
Sbjct: 3970 YFTQSFLTGVSQNYARKYTIPIDHIGFEFEV-TPQETVMENNPEDGAYIKGLFLEGARWD 4028
Query: 4343 RKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSDRASF 4398
RK + E+ P L +P I +P ES + +Y CP Y R G + ++
Sbjct: 4029 RKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNY 4088
Query: 4399 VIGIDLRSGAMTPDHWIKRGTALLMSLDS 4427
V+ I+L + M HWI RG A L LD+
Sbjct: 4089 VLSIELPTD-MPQKHWINRGVASLCQLDN 4116
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 2205 bits (5714), Expect = 0.0
Identities = 1344/4090 (32%), Positives = 2162/4090 (52%), Gaps = 146/4090 (3%)
Query: 412 FFGAQGPQITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMT 471
F G +G +++ + ++ + F + L L +++T + D ++F ++DL+
Sbjct: 467 FSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRL 526
Query: 472 QNLITSAFELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVN---- 527
+ AF+ + H LLD L R + R K + L +FN +L V
Sbjct: 527 GTIFIQAFDDAPGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYS 586
Query: 528 ----RERNKKWPDLEPYVAQYSGKARWVHILRRRIDRVMTCLAG-AHFLPRIGTGKESVH 582
E + + + +G RW LR+RI + H GK
Sbjct: 587 QHVQEEAELGFSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQ 646
Query: 583 TYQQMVQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFA 642
Y+ M+ +++ + +++W ++ + L PLL+ E + +NF+ L+ +
Sbjct: 647 KYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKE-ITINFNPQLISVLK 705
Query: 643 EIDYWE-RLLFETPHYVVNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERI 701
E+ Y E R + P + + R L NL L+A YN+++ L E L +E +
Sbjct: 706 EMSYLEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEEL 765
Query: 702 RLLDKKIHPGLKKLHWALKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEK 761
+ +D ++ + L+W +G + +TE ++ + + K + I +
Sbjct: 766 QNIDLRLRAAEETLNWKTEGICDY-VTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTP 824
Query: 762 LLVRISGKRV-YRDLEFEEDQRE-HRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQ 819
+ GKR L+ D+ E + +++ + +H ++ + +F D
Sbjct: 825 IFKTKDGKRESLLSLDDRHDRMEKYYNLIKESGLKIH----ALVQENLGLFSAD--PTSN 878
Query: 820 QWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQ 879
W Y+ +D ++ + L ++ SL L + N + K P+F+ + L ++ +
Sbjct: 879 IWKTYVNSIDNLLLNGFFLAIECSLKYLLE--NTECKAGLTPIFEAQLSL------AIPE 930
Query: 880 VEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQD--EDIKKI 937
+ F P+L++ GV + + I+ +P ++ + V+ D D+ +
Sbjct: 931 LVFYPSLES--GVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQVDLDGIPDLANM 988
Query: 938 QTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQRL----------------- 980
+ + + L Y T+ Y ++ ++ + ++
Sbjct: 989 RRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGI 1048
Query: 981 --NPPV-SSFVADIARYTEVANNVQKEETVTNIQ-FVLLDCSHLKFSLVQHCNEWQNKFA 1036
NPP+ S F I Y + V + E + ++ +D K SL+ W F
Sbjct: 1049 PENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFK 1108
Query: 1037 TLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVS--LQLVDALKHDLANVETQIPP 1094
L + L L ++K++ + + + + G+ + + A+K +N + P
Sbjct: 1109 QHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEP 1168
Query: 1095 IHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSAD 1154
+ + +L+ YE + ++V + L+ L +W ++ + KQ + + T L
Sbjct: 1169 LKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCT 1228
Query: 1155 DFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQ 1214
F + E F + F + + + + + M S+ + +F++
Sbjct: 1229 AFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIE--IQQMESTMASISESASLFEVNV 1286
Query: 1215 PPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKL 1274
P K L+ KE+ L+++W+ + + W+T + + E ME R + L
Sbjct: 1287 PDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNL 1346
Query: 1275 AKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESF 1334
KE R W+ S + ++ +++L+NPA+RERHW Q+ F + ++
Sbjct: 1347 DKEV--RAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDT- 1403
Query: 1335 TLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLR 1394
TL +++L + + +++ I A KE+ +E L+ + TW + P+ L
Sbjct: 1404 TLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLC 1463
Query: 1395 GTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLE 1454
E++ + LEDNQV L + S++V F ++V W++ LS + VI + VQR W +LE
Sbjct: 1464 SDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLE 1523
Query: 1455 NIFLG-EDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTIL 1513
+IF G EDIR QLP +S F+ ++ ++K + K N +++T+ PGL + L ++ L
Sbjct: 1524 SIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRL 1583
Query: 1514 EDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQK 1573
+K+L YL+TKR FPRFYFLS+ DLL+IL P+ VQ HL K FDN+ +R Q
Sbjct: 1584 CLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQL 1643
Query: 1574 VGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALR 1633
++GM+S + EY+ F G VE WL V M+ T+R + A
Sbjct: 1644 DASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYE 1703
Query: 1634 KFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKY 1693
+ R++W+ + QV +T +QI WT +V +E + + KK QV+ L
Sbjct: 1704 E--KPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKK-QVAQLKTL 1760
Query: 1694 SEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDD 1753
+ G L+K R KI+ + TI++HARDV+ K+ + + +F WLSQLR W+ ++
Sbjct: 1761 ITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKH 1820
Query: 1754 CVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETV 1813
C + QF Y+YEYLGN+ RLVITPLTDRCY+TLT +LHL G+P GPAGTGKTET
Sbjct: 1821 CFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETT 1880
Query: 1814 KDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQIL 1873
KDLG+ALGI V V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSVVA Q+
Sbjct: 1881 KDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVK 1940
Query: 1874 CILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDS 1933
I A+ F F G EI+L S GIFITMNPGYAGRTELPENLKS+FRP AMVVPD
Sbjct: 1941 SIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDF 2000
Query: 1934 TLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRL 1993
LI EI+L EGF + LA+K TLY L + LS+QDHYD+GLRA+ S+L AG +R
Sbjct: 2001 ELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRG 2060
Query: 1994 QPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIR 2053
PD +++VL+ S+RD NI K+ + D P+F ++ DLFP +++P V + I
Sbjct: 2061 DPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIV 2120
Query: 2054 DMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFN 2113
D+ LQ+ + KV QL E RHS +VG G+GK S + R+ +
Sbjct: 2121 DLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGK-----------SQVLRSLHKTYQ 2169
Query: 2114 IVREFP----LNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGP 2169
I++ P LNPKA++ EL+G + +T EW DG+ SS+MR KWIL DG
Sbjct: 2170 IMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGD 2229
Query: 2170 VDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDY 2229
+D +WIE++N+VMDDNKVLTL + ERI + + LLFE+ L A+PATVSR G++Y +
Sbjct: 2230 IDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINP 2289
Query: 2230 ADLGWKPYVQSWLEKRP-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLC 2288
ADLGW P V SW+EKR + E L +F+K + L + K+++P+PE S + +C
Sbjct: 2290 ADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVC 2349
Query: 2289 KLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEG-- 2346
L L T E+ PAD + E FVF+ IW+ ++ ++ ++ Y E
Sbjct: 2350 HLLECLLTTED--IPADCPKEI--YEHYFVFAAIWAFGGAMVQD---QLVDYRAEFSKWW 2402
Query: 2347 -------SFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYN 2399
FP++ T+++Y++DP+ + + + KL + + P P +V T +T+R
Sbjct: 2403 LTEFKTVKFPSQGTIFDYYIDPETKKFEPW-SKLVPQFEFDPEMPLQACLVHTSETIRVC 2461
Query: 2400 YLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIE 2459
Y + L+A Q P++LVG GTGK+ + + L SL + V V + TTS +Q+++E
Sbjct: 2462 YFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLE 2521
Query: 2460 SRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTI 2519
+EK+ Y P G K +I F+DD+NMP D +G+ P +IR +DYG WYDR+K ++
Sbjct: 2522 KPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSL 2581
Query: 2520 KYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQ--KLQDF 2577
K I + ++ M P G T I+PRL+ F++ ++FP + I+ ++ Q KL +F
Sbjct: 2582 KEITNVQYVSCMNPTAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF 2640
Query: 2578 EEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTK 2637
++ + + L + + FLPT K HY+FNLRD + +FQG+L ++ + +
Sbjct: 2641 PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST 2700
Query: 2638 SSITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF- 2696
+ RL++HE RV+ D++V+ D + F I ++ L FD + ++ P ++ F
Sbjct: 2701 WDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFA 2760
Query: 2697 --LKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQP 2754
+ EPK Y + +L + AL +N +V M LVLF +A+ H+ I R++ P
Sbjct: 2761 NGIGEPK-YMPVQSWELLTQTLVEALENHNEVNTV--MDLVLFEDAMRHVCHINRILESP 2817
Query: 2755 RGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKT 2814
RGN LLVG+GGSG+QSL RLA+ I FQI + K Y+ Q+F+ D+ L +AGV+
Sbjct: 2818 RGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLN 2877
Query: 2815 TSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSL 2874
T F+ D Q+ADE FL IN++L+SGE+P+LY DE E I S++ ++ + + + ++ ++
Sbjct: 2878 TVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENC 2937
Query: 2875 FAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCL 2934
+ + I+R++ L + LC SP+G+ R R++PA+VNCT I+WF EWPQ+AL V+ + L
Sbjct: 2938 WKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFL 2997
Query: 2935 IGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLG 2994
+ G + + + +++ +H SV Q SQ L +R+NY TP +LE + Y+ LL
Sbjct: 2998 QNTE-GIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLH 3056
Query: 2995 EKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKR 3054
R+EL + +L GL K+ T +V + +L + ++ + + ++ + ++ +
Sbjct: 3057 RHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETD 3116
Query: 3055 EADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIK 3114
+ ++ +K+AV ++ + + ++DL +A PAL A AL +LNK ++ E+K
Sbjct: 3117 KVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELK 3176
Query: 3115 SYGRPPAQVEIVMQAVMIL---RGNEP---TWAEAKRQLGE-QNFIKSLINFDKDNISDK 3167
S+G PP V V AVM+L RG P +W AK + + F+ SLINF+K+NI +
Sbjct: 3177 SFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHEN 3236
Query: 3168 VLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQL 3227
LK I Y P+F P+ + S AA LC WV + + ++ VEPKR +N A A L
Sbjct: 3237 CLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADL 3296
Query: 3228 REKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLA 3287
Q LA + K+ + E L L ++++ A K + ++++E + + A LV GLA
Sbjct: 3297 TAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLA 3356
Query: 3288 GEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVP 3347
E RW + VQ ++ L GD LL AF+SY+G F YR ++++ W + +L+ P
Sbjct: 3357 SENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTP 3416
Query: 3348 CSPSFAID--NFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWI 3405
+ A+D L + V W +GLP+D S EN I+ RW LM+DPQ Q +KWI
Sbjct: 3417 IPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWI 3476
Query: 3406 KNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGR 3465
KN + G+ L++ + YL+I+E A+ G VL++N++E +DP L P+L + V + G
Sbjct: 3477 KN-KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG-- 3533
Query: 3466 LLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRK 3525
++IGDKE EYN FR + TKL+NPHY PE A+ T++NF V GLE QLL VV
Sbjct: 3534 RFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSM 3593
Query: 3526 ERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATE 3585
ERP+LE+ K L K LK LED +L L+ A+G+ L + LV L +K TA E
Sbjct: 3594 ERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAE 3653
Query: 3586 VTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILS 3645
V ++++ ++ TE+ + ARE YRP A RAS+L+F++ND+ I PMYQFSL A+ +F +
Sbjct: 3654 VEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKA 3713
Query: 3646 IDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDE 3705
++++ L +R+ L D T++VY+YT R LFE KL + + +IL + ++N E
Sbjct: 3714 VERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVE 3773
Query: 3706 YNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWY 3765
+F LR V ++ +L+ W + L + F L E + W +
Sbjct: 3774 LDFLLRSPVQTGTASPVE-----FLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFV 3828
Query: 3766 TNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMK 3825
+ PEK LP EW+N +QR+ ++R++R DR+ + + F+ LGS+++ L+
Sbjct: 3829 ESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFA 3887
Query: 3826 SVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLR 3882
+ E+S P +P+ FILSPGVDP + +G Q FH +SLGQGQ +A L
Sbjct: 3888 TSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALD 3947
Query: 3883 EGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPIS 3937
+GHWV L N HL W+ L+K +E+ E+ HP FR+++S+ P P P
Sbjct: 3948 LAAKKGHWVILQNIHLVAKWLSTLEKKLEE-HSENSHPEFRVFMSAEPAPSPEGHIIPQG 4006
Query: 3938 ILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKK 3997
IL+ SIK+T EPP G+ AN+ + ++ CS+ ++K +LF+LC+FH+V+ ER+K
Sbjct: 4007 ILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRK 4066
Query: 3998 FLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRL 4057
F GWN Y FN D +S N+L +L+ + P+D L+YL I YGGH+TDDWDRRL
Sbjct: 4067 FGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRL 4126
Query: 4058 LTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNA 4117
TY+ ++ + L LS + +P + Y +YI + P +G HPNA
Sbjct: 4127 CRTYLGEFIRPEMLE---GELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNA 4183
Query: 4118 DVASQITEAQTLFDTLLSLQPQITPTRAG-GQTREEKVLELAADVKQKIPEMIDYEGTQK 4176
++ ++ LF T+L LQP+ + R G G TREEKV L ++ +++ + +
Sbjct: 4184 EIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMA 4243
Query: 4177 LLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHV 4236
+ + +P VV QE R N L + I SL +LE G++G + M++ +E + N ++ V
Sbjct: 4244 KVE-ERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMV 4302
Query: 4237 PPLWG-KAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQS 4295
P W +AYPS LAAW DL R+++ E W P WL+GF P FLTA++QS
Sbjct: 4303 PESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQS 4362
Query: 4296 SARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQ 4355
+AR+N +D ++ + ++ + PP++G ++ GL++EGA WD + + EA+
Sbjct: 4363 TARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKD 4422
Query: 4356 LVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWI 4415
L MP + + + K+ + +YSCP Y R ++V +L++ P W+
Sbjct: 4423 LTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRG-----PTYVWTFNLKT-KENPSKWV 4476
Query: 4416 KRGTALLMSL 4425
G ALL+ +
Sbjct: 4477 LAGVALLLQI 4486
Score = 96.7 bits (239), Expect = 5e-19
Identities = 75/289 (25%), Positives = 134/289 (46%), Gaps = 19/289 (6%)
Query: 123 GLKLELGMPVQTQNQL-----VYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGG 177
GL + G+ V ++ L ++F+R P P ++F V G + + L L
Sbjct: 80 GLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSE 139
Query: 178 VFAPQIFANT----GWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNM--- 230
V P + AN WP I H H L+ +++G T+L +PA + M
Sbjct: 140 VVLP-VLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFA 198
Query: 231 --KPEMVIK--DKELVQRLETSMIHWTRQIKEMLSAQET--VETGENLGPLEEIEFWRNR 284
K E V+ DK ++ +E+++I W+ Q++ +L + + + GEN P E+EFW++R
Sbjct: 199 DSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSR 258
Query: 285 CMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKE 344
DL I QL V+ + +L +SSY F + + + +AQ L L+
Sbjct: 259 YEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQR 318
Query: 345 PYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKVCD 393
+ L + ++ +L L+ ++ +IW Y + RLT L +++C+
Sbjct: 319 HLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICN 367
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 2194 bits (5686), Expect = 0.0
Identities = 1364/4039 (33%), Positives = 2146/4039 (53%), Gaps = 194/4039 (4%)
Query: 446 LDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIK 505
LD ++ + DY F I+DL+ + F+ + LL L R I
Sbjct: 491 LDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 550
Query: 506 RTYDKKAVDLYMLFNSEL--------ALVNRERNKKWPDLEPYVAQYSGKARWVHILRRR 557
+ + LF++EL A + P + + +G+ +W L+ R
Sbjct: 551 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 610
Query: 558 IDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVR----KTFQEWTSSLDKDCIRR 613
++ M L H + +G E+ TYQ+ + + EL+R K +Q+W + +D+DC
Sbjct: 611 LEVSMKHLK--HVEHPVMSGAEAKLTYQKYDEMM-ELLRCHREKIYQQWVAGVDQDCHFN 667
Query: 614 LDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWE-RLLFETPHYVVNVAERAEDLRILR 672
L PL+ + + ++ VNF K+L+ + E+ Y + E P ++ E R
Sbjct: 668 LGQPLI-LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFV 726
Query: 673 ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732
NL L+ YN ++ + E L K + +D K+ L W +G + I E R
Sbjct: 727 GNLELIVGWYNEVMKAV---EFLLIKSELEAIDVKLLSAETTLFWNGEGVFQY-IQEVRE 782
Query: 733 HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKL 792
+Q + + K + I ++ S L E +++++E + ++
Sbjct: 783 ILHNLQNRMQKAKQNIEGISQAMKDWSANPL-----------FERKDNKKEALLDLDGRI 831
Query: 793 MNLHQ----------DVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKW 842
NL++ + ++ + E+F+ D + W Y+I +D M+ D ++
Sbjct: 832 ANLNKRYAAVRDAGVKIQAMVAENAELFRAD--TLSLPWKDYVIYIDDMVLDEFDQFIRK 889
Query: 843 SLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQT---------LAGVV 893
SL L + D +P LF++ + L D + F+PTL+ + G+V
Sbjct: 890 SLSFLMDNMVIDESIAP--LFEIRMELDED------GLTFNPTLEVGSDRGFLALIEGLV 941
Query: 894 NDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQ 953
NDI N + ++ + R + +E + D+ +++ ++SS + N +
Sbjct: 942 NDIYN-----------VARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAE 990
Query: 954 NYLKTWDMYREIWEINKDSFIHRY--------------------QRLNPPVSSFVADIAR 993
Y +++ Y +W N F+ + + P ++ F I
Sbjct: 991 EYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDS 1050
Query: 994 YTEVANNVQK-EETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHT 1052
Y ++ V K E T ++ DC K +L+ W F L L +L
Sbjct: 1051 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1110
Query: 1053 YLKENAEKISRPPQTLEELGVSLQLVDALKHDL------ANVETQIPPIHEQFAILEKYE 1106
++K +++P + + G LV+ + H + A + P+ + +L+ Y
Sbjct: 1111 FMKVARMGLTKPLKEGDYDG----LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYG 1166
Query: 1107 VPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLED 1166
+ + + L L W ++ + K + + + L F+ K H E
Sbjct: 1167 EEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRER 1226
Query: 1167 FEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKE 1226
F + F+ + + + + + + AM +L + G+F++ P K L+ +E
Sbjct: 1227 FRREAPFSFSDP--NPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHRE 1284
Query: 1227 LDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEII 1286
+ L+++W++ + +WKT ++ + E M+ + + L KE K W+
Sbjct: 1285 VRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMK--TWDAF 1342
Query: 1287 ETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQ 1346
+ ++ ++ +S+L+NPA+RERHW Q+ Q +F SE TL +++L +
Sbjct: 1343 VGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKM-SEETTLADLLQLNLHS 1401
Query: 1347 HVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDN 1406
+ +++ I A KE +E L+ + TW + + P+ G L+ +E + + LEDN
Sbjct: 1402 YEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDN 1461
Query: 1407 QVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLG-EDIRKQ 1465
QV L + S+++ F K+V W++ LS VI + VQR W +LE+IF+G EDIR Q
Sbjct: 1462 QVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQ 1521
Query: 1466 LPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLE 1525
LP +S FD +N +KA+M+ K N + +T PGL + L + L +K+L YLE
Sbjct: 1522 LPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLE 1581
Query: 1526 TKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVG 1585
TKR FPRFYF+S+ DLL+IL +P V HL K FD++ L+ + +G
Sbjct: 1582 TKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLG 1641
Query: 1586 MFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKE 1645
M+S + EY+ F L G VE WL V M TLR + + + R++W+ +
Sbjct: 1642 MYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEE--KPREQWILD 1699
Query: 1646 WAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIM 1705
+ QV +T +QI WT +V +E + I KK Q+S LN + GNL
Sbjct: 1700 YPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKK-QISQLNVLITLLMGNLNAGD 1758
Query: 1706 RLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQY 1765
R+KI+ + TI++HARDV+ K+ + + +F W +QLR W+++ C + Q QY
Sbjct: 1759 RMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQY 1818
Query: 1766 NYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVI 1825
+YEYLGN+ RLVITPLTDRCY+TLT +LHL GG+P GPAGTGKTET KDLG+ALG V
Sbjct: 1819 SYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVY 1878
Query: 1826 VVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTH 1885
V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSV+A Q+ C+ A+ A
Sbjct: 1879 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKA 1938
Query: 1886 FHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEG 1945
F+F G I L+ + GIFITMNPGYAGR ELPENLK++FRP AMVVPD LI EI+L EG
Sbjct: 1939 FNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEG 1998
Query: 1946 FGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLL 2005
F ++LA+K TLY+L + LS+QDHYD+GLRA+ S+L AG +R P +++VL+
Sbjct: 1999 FLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMR 2058
Query: 2006 SMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLT 2065
++RD NI K+ + D P+F ++ DLFP +++P + ++Q I ++ LQ+ +
Sbjct: 2059 ALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVL 2118
Query: 2066 KVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKAL 2125
KV QL E RHS IVG GSGK+ + L + +L R L+PKA+
Sbjct: 2119 KVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK-------PVAVDLDPKAV 2171
Query: 2126 SLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDN 2185
+ EL+G + T EW DG+ S++MR KWI+ DG +D +WIE++N+VMDDN
Sbjct: 2172 TCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDDN 2231
Query: 2186 KVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKR 2245
KVLTL + ERI + + L+FE+ L A+PATVSR G++Y + ADLGW P V SW+E+R
Sbjct: 2232 KVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERR 2291
Query: 2246 P-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPA 2304
++E L +F+K + L + K++ P+PE + I ++ L L T + +
Sbjct: 2292 KVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPDS 2351
Query: 2305 DGENYVTMVEMTFVFSMIWSVCASV--DEEGRKRIDS---YLREIEG-SFPNKDTVYEYF 2358
E Y E+ FVF+ W+ ++ D+ R++ ++ E + FP++ T+++Y+
Sbjct: 2352 PRELY----ELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDYY 2407
Query: 2359 VDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPV 2418
+DP + + + DK+P S+ P+ P +V T +T+R Y + L+ P++LVG
Sbjct: 2408 IDPDTKKFLPWTDKVP-SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGNA 2466
Query: 2419 GTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSM 2478
GTGK+ + L+SL + + V V + TTS +Q ++E +EK++ Y P G K +
Sbjct: 2467 GTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKL 2526
Query: 2479 ITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGR 2538
+ F+DD+NMP D +G+ P LIR +D+ WYDR K T+K I +A M P G
Sbjct: 2527 VYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSF 2586
Query: 2539 TVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL--QDFEEEVKPIGNVVTEATLDMY 2596
T+ S RL+ F + ++FP + + I+ T++ Q L + ++ I + + A L ++
Sbjct: 2587 TIDS-RLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALALH 2645
Query: 2597 NTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRL 2656
+ FLPT K HY+FNLRD+S +FQG+L + + T + RLW+HE RV+ D++
Sbjct: 2646 QKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKM 2705
Query: 2657 VDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF---LKEPKVYEDLTDLTVLK 2713
VD D E + FFD L +K P IF F + +PK Y +TD+ L
Sbjct: 2706 VDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPK-YVPVTDMAPLN 2763
Query: 2714 TVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLAR 2773
++ L+ YN +V M LVLF +A+ HI RI R++ PRGN LLVG+GGSG+QSL+R
Sbjct: 2764 KLLVDVLDSYNEVNAV--MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSR 2821
Query: 2774 LASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDI 2833
LA+ I FQI + K Y + + D+ Y +A V+ + F+ D+Q+A+E FL I
Sbjct: 2822 LAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLI 2881
Query: 2834 NNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLS 2893
N++L+SGE+P L+ DE E I S + Q + + ++ ++ + + IE+V+ L ++LC S
Sbjct: 2882 NDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFS 2941
Query: 2894 PMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCL---IGVDLGTQENIHRKVA 2950
P+G R R++PA+VNCT I+WF EWP++AL+ V+ + L G+ + I ++
Sbjct: 2942 PVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPV-----IKASIS 2996
Query: 2951 QIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTG 3010
+H +V + S+ L RR+NY TP +LE + Y+ LL +KR EL+A+ +L G
Sbjct: 2997 FFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENG 3056
Query: 3011 LFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKI 3070
L K+ T +V + +L + ++ + + + + L+ +V + E ++KA+ A+ E++
Sbjct: 3057 LMKLQSTASQVDDLKAKLAIQEAELKQ-KNESADQLIQVVGIEAEKVSKEKAI-ADQEEV 3114
Query: 3071 AVEEIKCQALADN--AQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQ 3128
VE I + DL +A PAL A AL++LNK ++ E+KS+G PP V V
Sbjct: 3115 KVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTA 3174
Query: 3129 AVMILRG------NEPTWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGAYCAQPDF 3181
AVMIL + +W AK +G+ F+ SL FDK++I + LK Y P F
Sbjct: 3175 AVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTF 3234
Query: 3182 QPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKL 3241
P+ I S AA LC W + + +Y V PKR + A A+L E Q L+ + K+
Sbjct: 3235 DPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKI 3294
Query: 3242 REVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLE 3301
E+ L L +++ A+K + +++++ + A LV GLA E RW E+V+
Sbjct: 3295 AELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFR 3354
Query: 3302 EDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAID--NFLC 3359
L GD LL +AF+SY+G F YR+E++ + WI I L+VP + +D + L
Sbjct: 3355 SQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLT 3414
Query: 3360 NPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDL 3419
+ V WN QGLPSD STEN I+ RW L++D Q Q +KWIKN + LK I L
Sbjct: 3415 DDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-LKAIRL 3473
Query: 3420 QMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNT 3479
YL ++E AI G +L++N+ E +DP L+P+L ++ + G ++IGDKEVEY+
Sbjct: 3474 GQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHP 3531
Query: 3480 NFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVI 3539
FR + TK NPHY PE A+ T++NF V GLE QLL VV KERP+LE+ K +L
Sbjct: 3532 KFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTK 3591
Query: 3540 NIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEIN 3599
+ K LKELED +L L+ A+G+ L D LV L T+K TA+E+ E++ ++ TE+
Sbjct: 3592 SQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVK 3651
Query: 3600 TDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRI 3659
+ ARE YRP A+RAS+L+F+LND+ I+P+YQFSL A+ +F +I ++ +N+++ R+
Sbjct: 3652 INEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRV 3711
Query: 3660 DYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLR----GGVV 3715
L D TY+VY YT R LFER KL+F + ++L +LN E +F LR GVV
Sbjct: 3712 INLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVV 3771
Query: 3716 LDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAML 3775
+P +L W I L ++ F L + E + W + APEK +
Sbjct: 3772 --------SPV-DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIF 3822
Query: 3776 PGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRS 3835
P EW+N +Q++ +VR LR DR+ + + +F+ +GS+F+E + E+S+P +
Sbjct: 3823 PKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPST 3881
Query: 3836 PLVFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLREGVTQGHWVF 3892
+ FILSPGVDP + L + +G + H +SLGQGQ +A L +GHWV
Sbjct: 3882 SIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVI 3941
Query: 3893 LANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPISILQVSIKMTT 3947
L N HL W+ LDK +E+ H +R+++S+ P P P IL+ +IK+T
Sbjct: 3942 LQNIHLVARWLGTLDKKLERYST-GSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 4000
Query: 3948 EPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIY 4007
EPP G+ AN+ + L ++ C+K ++K +LF+LC+FH+V+ ER+KF GWN Y
Sbjct: 4001 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4060
Query: 4008 GFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFC 4067
FN+ D +S N+L YL+ + PWD L+YL I YGGH+TDDWDRRL TY+ +Y
Sbjct: 4061 PFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIR 4120
Query: 4068 DQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQ 4127
+ L + + IP + Y EYI + P +G HPNA++ ++
Sbjct: 4121 TEMLEGD---VLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSE 4177
Query: 4128 TLFDTLLSLQPQITPTRAG-GQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLN 4186
LF T+L +QP+ T + AG G +REEKV + D+ +KIPE + A + +P
Sbjct: 4178 KLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIM-AKAAEKTPYV 4236
Query: 4187 VVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYP 4245
VV QE +R N L + SL +L G++G + ++T +E++ +F VP W +AYP
Sbjct: 4237 VVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYP 4296
Query: 4246 SQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVD 4305
S LAAW DL +R+ + E W + P WL+GF P FLTA++QS AR+N +D
Sbjct: 4297 SMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLD 4356
Query: 4306 SLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHF 4365
+ V+ + ++ PP++G +V GL++EGA WD + + EA +L MP I
Sbjct: 4357 KMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFI 4416
Query: 4366 RPAESRKKSAKGMYSCPCY 4384
+ + K +Y CP Y
Sbjct: 4417 KAIPVDRMETKNIYECPVY 4435
Score = 107 bits (268), Expect = 2e-22
Identities = 74/315 (23%), Positives = 147/315 (46%), Gaps = 16/315 (5%)
Query: 93 VWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWE 152
+ +E+ A+ F + P +L + ++ + LG P +++ VYFI+ I +
Sbjct: 31 IGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFPQSLKSKGVYFIKTKSENINKD 90
Query: 153 NFEATVQFGTVRGPYIPALLRLLGGVFAPQIFAN---TGWPESIRNHFASHLHKFLACLT 209
N+ A + +G + + L+ ++ V + + + GWP+ + +H+ +
Sbjct: 91 NYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMF 150
Query: 210 DTRYKLEGHTVLYIPA---------EAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML 260
K++G T+L IP E+M P + D L+ +ET++I W+ QI+++L
Sbjct: 151 VMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSL--DNLLLHAIETTIIDWSHQIRDVL 208
Query: 261 SAQETVETGENLGPLEEIEF--WRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPF 318
S + L PL ++EF W R ++L I +QL + V + IL AKS Y
Sbjct: 209 SKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPAL 268
Query: 319 MKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHY 378
+ + +G ++A + +L L+ +E+ + + + K++ I IW S +Y
Sbjct: 269 QNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYY 328
Query: 379 NTRERLTSLFRKVCD 393
NT R+ + ++ C+
Sbjct: 329 NTPARIIVILQEFCN 343
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 2162 bits (5603), Expect = 0.0
Identities = 1363/4074 (33%), Positives = 2144/4074 (52%), Gaps = 237/4074 (5%)
Query: 446 LDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIK 505
LD ++ + DY F I+DL+ + F+ + LL L R I
Sbjct: 479 LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538
Query: 506 RTYDKKAVDLYMLFNSEL--------ALVNRERNKKWPDLEPYVAQYSGKARWVHILRRR 557
+ + LF++EL A + P + + +G+ +W L+ R
Sbjct: 539 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598
Query: 558 IDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVR----KTFQEWTSSLDKDCIRR 613
++ M L H + +G E+ TYQ+ + + EL+R K +Q+W + +D+DC
Sbjct: 599 LEVSMKHLK--HVEHPVMSGAEAKLTYQKYDEMM-ELLRCHREKIYQQWVAGVDQDCHFN 655
Query: 614 LDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWE-RLLFETPHYVVNVAERAEDLRILR 672
L PL+ + + ++ VNF K+L+ + E+ Y + E P ++ E R
Sbjct: 656 LGQPLI-LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFV 714
Query: 673 ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732
NL L+ YN I ++ E L K + +D K+ L W +G + I E R
Sbjct: 715 GNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQY-IQEVRE 773
Query: 733 HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKL 792
+Q + + K + I ++ S L E +++++E + ++
Sbjct: 774 ILHNLQNRMQKAKQNIEGISQAMKDWSANPL-----------FERKDNKKEALLDLDGRI 822
Query: 793 MNLHQ----------DVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKW 842
NL++ + ++ + E+F+ D + W Y+I +D M+ D ++
Sbjct: 823 ANLNKRYAAVRDAGVKIQAMVAENAELFRAD--TLSLPWKDYVIYIDDMVLDEFDQFIRK 880
Query: 843 SLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQT---------LAGVV 893
SL L + D +P LF++ + L D + F+PTL+ + G+V
Sbjct: 881 SLSFLMDNMVIDESIAP--LFEIRMELDED------GLTFNPTLEVGSDRGFLALIEGLV 932
Query: 894 NDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQ 953
NDI N + ++ + R + +E + D+ +++ ++SS + N +
Sbjct: 933 NDIYN-----------VARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAE 981
Query: 954 NYLKTWDMYREIWEINKDSFIHRY--------------------QRLNPPVSSFVADIAR 993
Y +++ Y +W N F+ + + P ++ F I
Sbjct: 982 EYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDS 1041
Query: 994 YTEVANNVQK-EETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHT 1052
Y ++ V K E T ++ DC K +L+ W F L L +L
Sbjct: 1042 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1101
Query: 1053 YLKENAEKISRPPQTLEELGVSLQLVDALKHDL------ANVETQIPPIHEQFAILEKYE 1106
++K +++P + + G LV+ + H + A + P+ + +L+ Y
Sbjct: 1102 FMKVARMGLTKPLKEGDYDG----LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYG 1157
Query: 1107 VPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLED 1166
+ + + L L W ++ + K + + + L F+ K H E
Sbjct: 1158 EEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRER 1217
Query: 1167 FEFKGHFT-SNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEK 1225
F + F+ S+ +L+++ ++ ++ A+ + G+F++ P K L+ +
Sbjct: 1218 FRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSG-------GLFEVPVPDYKQLKACHR 1270
Query: 1226 ELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEI 1285
E+ L+++W++ + +WKT ++ + E M+ + + L KE K W+
Sbjct: 1271 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMK--TWDA 1328
Query: 1286 IETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMD 1345
+ ++ ++ +S+L+NPA+RERHW Q+ Q +F SE TL +++L +
Sbjct: 1329 FVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKM-SEETTLADLLQLNLH 1387
Query: 1346 QHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALED 1405
+ +++ I A KE +E L+ + TW + + P+ G L+ +E + + LED
Sbjct: 1388 SYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLED 1447
Query: 1406 NQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLG-EDIRK 1464
NQV L + S+++ F K+V W++ LS VI + VQR W +LE+IF+G EDIR
Sbjct: 1448 NQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRT 1507
Query: 1465 QLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYL 1524
QLP +S FD +N +KA+M+ K N + +T PGL + L + L +K+L YL
Sbjct: 1508 QLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYL 1567
Query: 1525 ETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAV 1584
ETKR FPRFYF+S+ DLL+IL +P V HL K FD++ L+ + +
Sbjct: 1568 ETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGL 1627
Query: 1585 GMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVK 1644
GM+S + EY+ F L G VE WL V M TLR + + + R++W+
Sbjct: 1628 GMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEE--KPREQWIL 1685
Query: 1645 EWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKI 1704
++ +QI WT +V +E + I K K Q+S LN + GNL
Sbjct: 1686 DYP-------AQIWWTTEVGLAFARLEEGYENAI-KDYNKKQISQLNVLITLLIGNLNAG 1737
Query: 1705 MRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQ 1764
R+KI+ + TI++HARDV+ K+ + +F W +QLR W+++ C + Q Q
Sbjct: 1738 DRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQ 1794
Query: 1765 YNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYV 1824
Y+YEYLGN+ RLVITPLTDRCY+TLT +LHL GG+P GPAGTGKTET KDLG+ALG V
Sbjct: 1795 YSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMV 1854
Query: 1825 IVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLT 1884
V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSV+A Q+ C+ A+ A
Sbjct: 1855 YVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKK 1914
Query: 1885 HFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGE 1944
F+F G I L+ + GIFITMNPGYAGR ELPENLK++FRP AMVVPD LI EI+L E
Sbjct: 1915 AFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAE 1974
Query: 1945 GFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLL 2004
GF ++LA+K TLY+L + LS+QDHYD+GLRA+ S+L AG +R P +++VL+
Sbjct: 1975 GFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLM 2034
Query: 2005 LSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTL 2064
++RD NI K+ + D P+F ++ DLFP +++P + ++Q I ++ LQ+ +
Sbjct: 2035 RALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFV 2094
Query: 2065 TKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKA 2124
KV QL E RHS IVG GSGK+ + L + +L R L+PKA
Sbjct: 2095 LKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK-------PVAVDLDPKA 2147
Query: 2125 LSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDD 2184
++ EL+G + T EW DG+ S++MR KWI+ DG +D +WIE++N+VMDD
Sbjct: 2148 VTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDD 2207
Query: 2185 NKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEK 2244
NKVLTL + ERI + + L+FE+ L A+PATVSR G++Y + ADLGW P V SW+E+
Sbjct: 2208 NKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIER 2267
Query: 2245 RP-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNP 2303
R ++E L +F+K + L + K++ P+PE + I ++ L L T +
Sbjct: 2268 RKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPD 2327
Query: 2304 ADGENYVTMVEMTFVFSMIWSVCASV--DEEGRKRIDS---YLREIEG-SFPNKDTVYEY 2357
+ E Y E+ FVF+ W+ ++ D+ R++ ++ E + FP++ T+++Y
Sbjct: 2328 SPRELY----ELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDY 2383
Query: 2358 FVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGP 2417
++DP + + + DK+P S+ P+ P +V T +T+R Y + L+ P++LVG
Sbjct: 2384 YIDPDTKKFLPWTDKVP-SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGN 2442
Query: 2418 VGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKS 2477
GTGK+ + L+SL + + V V + TTS +Q ++E +EK++ Y P G K
Sbjct: 2443 AGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502
Query: 2478 MITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGG 2537
++ F+DD+NMP D +G+ P LIR +D+ WYDR K T+K I +A M P G
Sbjct: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562
Query: 2538 RTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL--QDFEEEVKPIGNVVTEATLDM 2595
T+ S RL+ F + ++FP + + I+ T++ Q L + ++ I + + A L +
Sbjct: 2563 FTIDS-RLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALAL 2621
Query: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655
+ + FLPT K HY+FNLRD+S +FQG+L + + T + RLW+HE RV+ D+
Sbjct: 2622 HQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDK 2681
Query: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF---LKEPKVYEDLTDLTVL 2712
+VD D E + FFD L +K P IF F + +PK Y +TD+ L
Sbjct: 2682 MVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPK-YVPVTDMAPL 2739
Query: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772
++ L+ YN +V M LVLF +A+ HI RI R++ PRGN LLVG+GGSG+QSL+
Sbjct: 2740 NKLLVDVLDSYNEVNAV--MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLS 2797
Query: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832
RLA+ I FQI + K Y + + D+ Y +A V+ + F+ D+Q+A+E FL
Sbjct: 2798 RLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVL 2857
Query: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCL 2892
IN++L+SGE+P L+ DE E I S + Q + + ++ ++ + + IE+V+ L ++LC
Sbjct: 2858 INDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCF 2917
Query: 2893 SPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQI 2952
SP+G R R++PA+VNCT I+WF EWP++AL+ V+ + L + G + ++
Sbjct: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPWEVKASISFF 2976
Query: 2953 FVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLF 3012
+H +V + S+ L RR+NY TP +LE + Y+ LL +KR EL+A+ +L GL
Sbjct: 2977 MSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLM 3036
Query: 3013 KIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAV 3072
K+ T +V + +L + ++ + + + + L+ +V + E ++KA+ A+ E++ V
Sbjct: 3037 KLQSTASQVDDLKAKLAIQEAELKQ-KNESADQLIQVVGIEAEKVSKEKAI-ADQEEVKV 3094
Query: 3073 EEIKCQALADN--AQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAV 3130
E I + DL +A PAL A AL++LNK ++ E+KS+G PP V V AV
Sbjct: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154
Query: 3131 MILRG------NEPTWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQP 3183
MIL + +W AK +G+ F+ SL FDK++I + LK Y P F P
Sbjct: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214
Query: 3184 DIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLRE 3243
+ I S AA LC W + + +Y V PKR + A A+L E Q L+ + K+ E
Sbjct: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274
Query: 3244 VAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEED 3303
+ L L +++ A+K + +++++ + A LV GLA E RW E+V+
Sbjct: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334
Query: 3304 LGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAID--NFLCNP 3361
L GD LL +AF+SY+G F YR+E++ + WI I L+VP + +D + L +
Sbjct: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394
Query: 3362 TKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQM 3421
V WN QGLPSD STEN I+ RW L++D Q Q +KWIKN + LK I L
Sbjct: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-LKAIRLGQ 3453
Query: 3422 SDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNF 3481
YL ++E AI G +L++N+ E +DP L+P+L ++ + G ++IGDKEVEY+ F
Sbjct: 3454 KSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKF 3511
Query: 3482 RFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINI 3541
R + TK NPHY PE A+ T++NF V GLE QLL VV KERP+LE+ K +L +
Sbjct: 3512 RLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQ 3571
Query: 3542 AAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTD 3601
K LKELED +L L+ A+G+ L D LV L T+K TA+E+ E++ ++ TE+ +
Sbjct: 3572 NEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKIN 3631
Query: 3602 LAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDY 3661
ARE YRP A+RAS+L+F+LND+ I+P+YQFSL A+ +F +I ++ +N+++ R+
Sbjct: 3632 EARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVIN 3691
Query: 3662 LNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLR----GGVVLD 3717
L D TY+VY YT R LFER KL+F + ++L +LN E +F LR GVV
Sbjct: 3692 LTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVV-- 3749
Query: 3718 REGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPG 3777
+P +L W I L ++ F L + E + W + APEK + P
Sbjct: 3750 ------SPV-DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPK 3802
Query: 3778 EWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPL 3837
EW+N +Q++ +VR LR DR+ + + +F+ +GS+F+E + E+S+P + +
Sbjct: 3803 EWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSI 3861
Query: 3838 VFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLREGVTQGHWVFL- 3893
FILSPGVDP + L + +G + H +SLGQGQ +A L +GHWV L
Sbjct: 3862 FFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ 3921
Query: 3894 -------ANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPISILQV 3941
N HL W+ LDK +E+ H +R+++S+ P P P IL+
Sbjct: 3922 VRGGQHCRNIHLVARWLGTLDKKLERYST-GSHEDYRVFISAEPAPSPETHIIPQGILEN 3980
Query: 3942 SIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQL 4001
+IK+T EPP G+ AN+ + L ++ C+K ++K +LF+LC+FH+V+ ER+KF
Sbjct: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040
Query: 4002 GWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTY 4061
GWN Y FN+ D +S N+L YL+ + PWD L+YL I YGGH+TDDWDRRL TY
Sbjct: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100
Query: 4062 INDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVAS 4121
+ +Y + L + + IP + Y EYI + P +G HPNA++
Sbjct: 4101 LAEYIRTEMLEGD---VLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGF 4157
Query: 4122 QITEAQTLFDTLLSLQPQITPTRAG-GQTREEKV--------------LELAA------- 4159
++ LF T+L +QP+ T + AG G +REEK LEL
Sbjct: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217
Query: 4160 --------DVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLE 4211
D+ +KIPE + A + +P VV QE +R N L + SL +L
Sbjct: 4218 FQVKAVLDDILEKIPETFNMAEIM-AKAAEKTPYVVVAFQECERMNILTNEMRRSLKELN 4276
Query: 4212 KGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASR 4270
G++G + ++T +E++ +F VP W +AYPS LAAW DL +R+ + E W +
Sbjct: 4277 LGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTD 4336
Query: 4271 ARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVW 4330
P WL+GF P FLTA++QS AR+N +D + V+ + ++ PP++G +
Sbjct: 4337 FALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSY 4396
Query: 4331 VRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY 4384
V GL++EGA WD + + EA +L MP I + + K +Y CP Y
Sbjct: 4397 VYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450
Score = 107 bits (268), Expect = 2e-22
Identities = 74/315 (23%), Positives = 147/315 (46%), Gaps = 16/315 (5%)
Query: 93 VWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWE 152
+ +E+ A+ F + P +L + ++ + LG P +++ VYFI+ I +
Sbjct: 31 IGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFPQSLKSKGVYFIKTKSENINKD 90
Query: 153 NFEATVQFGTVRGPYIPALLRLLGGVFAPQIFAN---TGWPESIRNHFASHLHKFLACLT 209
N+ A + +G + + L+ ++ V + + + GWP+ + +H+ +
Sbjct: 91 NYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMF 150
Query: 210 DTRYKLEGHTVLYIPA---------EAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML 260
K++G T+L IP E+M P + D L+ +ET++I W+ QI+++L
Sbjct: 151 VMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSL--DNLLLHAIETTIIDWSHQIRDVL 208
Query: 261 SAQETVETGENLGPLEEIEF--WRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPF 318
S + L PL ++EF W R ++L I +QL + V + IL AKS Y
Sbjct: 209 SKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPAL 268
Query: 319 MKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHY 378
+ + +G ++A + +L L+ +E+ + + + K++ I IW S +Y
Sbjct: 269 QNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYY 328
Query: 379 NTRERLTSLFRKVCD 393
NT R+ + ++ C+
Sbjct: 329 NTPARIIVILQEFCN 343
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 2162 bits (5602), Expect = 0.0
Identities = 1363/4074 (33%), Positives = 2143/4074 (52%), Gaps = 237/4074 (5%)
Query: 446 LDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIK 505
LD ++ + DY F I+DL+ + F+ + LL L R I
Sbjct: 479 LDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLIL 538
Query: 506 RTYDKKAVDLYMLFNSEL--------ALVNRERNKKWPDLEPYVAQYSGKARWVHILRRR 557
+ + LF++EL A + P + + +G+ +W L+ R
Sbjct: 539 AEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQER 598
Query: 558 IDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVR----KTFQEWTSSLDKDCIRR 613
++ M L H + +G E+ TYQ+ + + EL+R K +Q+W + +D+DC
Sbjct: 599 LEVSMKHLK--HVEHPVMSGAEAKLTYQKYDEMM-ELLRCHREKIYQQWVAGVDQDCHFN 655
Query: 614 LDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWE-RLLFETPHYVVNVAERAEDLRILR 672
L PL+ + + ++ VNF K+L+ + E+ Y + E P ++ E R
Sbjct: 656 LGQPLI-LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFV 714
Query: 673 ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732
NL L+ YN I ++ E L K + +D K+ L W +G + I E R
Sbjct: 715 GNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQY-IQEVRE 773
Query: 733 HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKL 792
+Q + + K + I ++ S L E +++++E + ++
Sbjct: 774 ILHNLQNRMQKAKQNIEGISQAMKDWSANPL-----------FERKDNKKEALLDLDGRI 822
Query: 793 MNLHQ----------DVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKW 842
NL++ + ++ + E+F+ D + W Y+I +D M+ D ++
Sbjct: 823 ANLNKRYAAVRDAGVKIQAMVAENAELFRAD--TLSLPWKDYVIYIDDMVLDEFDQFIRK 880
Query: 843 SLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQT---------LAGVV 893
SL L + D +P LF++ + L D + F+PTL+ + G+V
Sbjct: 881 SLSFLMDNMVIDESIAP--LFEIRMELDED------GLTFNPTLEVGSDRGFLALIEGLV 932
Query: 894 NDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQ 953
NDI N + ++ + R + +E + D+ +++ ++SS + N +
Sbjct: 933 NDIYN-----------VARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAE 981
Query: 954 NYLKTWDMYREIWEINKDSFIHRY--------------------QRLNPPVSSFVADIAR 993
Y +++ Y +W N F+ + + P ++ F I
Sbjct: 982 EYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDS 1041
Query: 994 YTEVANNVQK-EETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHT 1052
Y ++ V K E T ++ DC K +L+ W F L L +L
Sbjct: 1042 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1101
Query: 1053 YLKENAEKISRPPQTLEELGVSLQLVDALKHDL------ANVETQIPPIHEQFAILEKYE 1106
++K +++P + + G LV+ + H + A + P+ + +L+ Y
Sbjct: 1102 FMKVARMGLTKPLKEGDYDG----LVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYG 1157
Query: 1107 VPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLED 1166
+ + + L L W ++ + K + + + L F+ K H E
Sbjct: 1158 EEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRER 1217
Query: 1167 FEFKGHFT-SNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEK 1225
F + F+ S+ +L+++ ++ ++ A+ + G+F++ P K L+ +
Sbjct: 1218 FRREAPFSFSDPNPYKSLNKVFLLKGIMEALSKSG-------GLFEVPVPDYKQLKACHR 1270
Query: 1226 ELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEI 1285
E+ L+++W++ + +WKT ++ + E M+ + + L KE K W+
Sbjct: 1271 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMK--TWDA 1328
Query: 1286 IETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMD 1345
+ ++ ++ +S+L+NPA+RERHW Q+ Q +F SE TL +++L +
Sbjct: 1329 FVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKM-SEETTLADLLQLNLH 1387
Query: 1346 QHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALED 1405
+ +++ I A KE +E L+ + TW + + P+ G L+ +E + + LED
Sbjct: 1388 SYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLED 1447
Query: 1406 NQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLG-EDIRK 1464
NQV L + S+++ F K+V W++ LS VI + VQR W +LE+IF+G EDIR
Sbjct: 1448 NQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRT 1507
Query: 1465 QLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYL 1524
QLP +S FD +N +KA+M+ K N + +T PGL + L + L +K+L YL
Sbjct: 1508 QLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYL 1567
Query: 1525 ETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAV 1584
ETKR FPRFYF+S+ DLL+IL +P V HL K FD++ L+ + +
Sbjct: 1568 ETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGL 1627
Query: 1585 GMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVK 1644
GM+S + EY+ F L G VE WL V M TLR + + + R++W+
Sbjct: 1628 GMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTYEE--KPREQWIL 1685
Query: 1645 EWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKI 1704
++ +QI WT +V +E + I KK Q+S LN + GNL
Sbjct: 1686 DYP-------AQIWWTTEVGLAFARLEEGYENAIRDYNKK-QISQLNVLITLLMGNLNAG 1737
Query: 1705 MRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQ 1764
R+KI+ + TI++HARDV+ K+ + +F W +QLR W+++ C + Q Q
Sbjct: 1738 DRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQ 1794
Query: 1765 YNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYV 1824
Y+YEYLGN+ RLVITPLTDRCY+TLT +LHL GG+P GPAGTGKTET KDLG+ALG V
Sbjct: 1795 YSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMV 1854
Query: 1825 IVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLT 1884
V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSV+A Q+ C+ A+ A
Sbjct: 1855 YVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKK 1914
Query: 1885 HFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGE 1944
F+F G I L+ + GIFITMNPGYAGR ELPENLK++FRP AMVVPD LI EI+L E
Sbjct: 1915 AFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAE 1974
Query: 1945 GFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLL 2004
GF ++LA+K TLY+L + LS+QDHYD+GLRA+ S+L AG +R P +++VL+
Sbjct: 1975 GFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLM 2034
Query: 2005 LSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTL 2064
++RD NI K+ + D P+F ++ DLFP +++P + ++Q I ++ LQ+ +
Sbjct: 2035 RALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFV 2094
Query: 2065 TKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKA 2124
KV QL E RHS IVG GSGK+ + L + +L R L+PKA
Sbjct: 2095 LKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRK-------PVAVDLDPKA 2147
Query: 2125 LSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDD 2184
++ EL+G + T EW DG+ S++MR KWI+ DG +D +WIE++N+VMDD
Sbjct: 2148 VTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIESLNTVMDD 2207
Query: 2185 NKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEK 2244
NKVLTL + ERI + + L+FE+ L A+PATVSR G++Y + ADLGW P V SW+E+
Sbjct: 2208 NKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIER 2267
Query: 2245 RP-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNP 2303
R ++E L +F+K + L + K++ P+PE + I ++ L L T +
Sbjct: 2268 RKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLTEKTVPPD 2327
Query: 2304 ADGENYVTMVEMTFVFSMIWSVCASV--DEEGRKRIDS---YLREIEG-SFPNKDTVYEY 2357
+ E Y E+ FVF+ W+ ++ D+ R++ ++ E + FP++ T+++Y
Sbjct: 2328 SPRELY----ELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTIFDY 2383
Query: 2358 FVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGP 2417
++DP + + + DK+P S+ P+ P +V T +T+R Y + L+ P++LVG
Sbjct: 2384 YIDPDTKKFLPWTDKVP-SFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVGN 2442
Query: 2418 VGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKS 2477
GTGK+ + L+SL + + V V + TTS +Q ++E +EK++ Y P G K
Sbjct: 2443 AGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKK 2502
Query: 2478 MITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGG 2537
++ F+DD+NMP D +G+ P LIR +D+ WYDR K T+K I +A M P G
Sbjct: 2503 LVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGS 2562
Query: 2538 RTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKL--QDFEEEVKPIGNVVTEATLDM 2595
T+ S RL+ F + ++FP + + I+ T++ Q L + ++ I + + A L +
Sbjct: 2563 FTIDS-RLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALAL 2621
Query: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655
+ + FLPT K HY+FNLRD+S +FQG+L + + T + RLW+HE RV+ D+
Sbjct: 2622 HQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDK 2681
Query: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF---LKEPKVYEDLTDLTVL 2712
+VD D E + FFD L +K P IF F + +PK Y +TD+ L
Sbjct: 2682 MVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPK-YVPVTDMAPL 2739
Query: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772
++ L+ YN +V M LVLF +A+ HI RI R++ PRGN LLVG+GGSG+QSL+
Sbjct: 2740 NKLLVDVLDSYNEVNAV--MNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLS 2797
Query: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832
RLA+ I FQI + K Y + + D+ Y +A V+ + F+ D+Q+A+E FL
Sbjct: 2798 RLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVL 2857
Query: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCL 2892
IN++L+SGE+P L+ DE E I S + Q + + ++ ++ + + IE+V+ L ++LC
Sbjct: 2858 INDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCF 2917
Query: 2893 SPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQI 2952
SP+G R R++PA+VNCT I+WF EWP++AL+ V+ + L + G + ++
Sbjct: 2918 SPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE-GIPWEVKASISFF 2976
Query: 2953 FVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLF 3012
+H +V + S+ L RR+NY TP +LE + Y+ LL +KR EL+A+ +L GL
Sbjct: 2977 MSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLM 3036
Query: 3013 KIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAV 3072
K+ T +V + +L + ++ + + + + L+ +V + E ++KA+ A+ E++ V
Sbjct: 3037 KLQSTASQVDDLKAKLAIQEAELKQ-KNESADQLIQVVGIEAEKVSKEKAI-ADQEEVKV 3094
Query: 3073 EEIKCQALADN--AQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAV 3130
E I + DL +A PAL A AL++LNK ++ E+KS+G PP V V AV
Sbjct: 3095 EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAV 3154
Query: 3131 MILRG------NEPTWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQP 3183
MIL + +W AK +G+ F+ SL FDK++I + LK Y P F P
Sbjct: 3155 MILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDP 3214
Query: 3184 DIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLRE 3243
+ I S AA LC W + + +Y V PKR + A A+L E Q L+ + K+ E
Sbjct: 3215 EFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAE 3274
Query: 3244 VAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEED 3303
+ L L +++ A+K + +++++ + A LV GLA E RW E+V+
Sbjct: 3275 LNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQ 3334
Query: 3304 LGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAID--NFLCNP 3361
L GD LL +AF+SY+G F YR+E++ + WI I L+VP + +D + L +
Sbjct: 3335 GVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDD 3394
Query: 3362 TKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQM 3421
V WN QGLPSD STEN I+ RW L++D Q Q +KWIKN + LK I L
Sbjct: 3395 ADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSE-LKAIRLGQ 3453
Query: 3422 SDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNF 3481
YL ++E AI G +L++N+ E +DP L+P+L ++ + G ++IGDKEVEY+ F
Sbjct: 3454 KSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKG--KYIKIGDKEVEYHPKF 3511
Query: 3482 RFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINI 3541
R + TK NPHY PE A+ T++NF V GLE QLL VV KERP+LE+ K +L +
Sbjct: 3512 RLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQ 3571
Query: 3542 AAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTD 3601
K LKELED +L L+ A+G+ L D LV L T+K TA+E+ E++ ++ TE+ +
Sbjct: 3572 NEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKIN 3631
Query: 3602 LAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDY 3661
ARE YRP A+RAS+L+F+LND+ I+P+YQFSL A+ +F +I ++ +N+++ R+
Sbjct: 3632 EARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVIN 3691
Query: 3662 LNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLR----GGVVLD 3717
L D TY+VY YT R LFER KL+F + ++L +LN E +F LR GVV
Sbjct: 3692 LTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVV-- 3749
Query: 3718 REGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPG 3777
+P +L W I L ++ F L + E + W + APEK + P
Sbjct: 3750 ------SPV-DFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPK 3802
Query: 3778 EWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPL 3837
EW+N +Q++ +VR LR DR+ + + +F+ +GS+F+E + E+S+P + +
Sbjct: 3803 EWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSI 3861
Query: 3838 VFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLREGVTQGHWVFL- 3893
FILSPGVDP + L + +G + H +SLGQGQ +A L +GHWV L
Sbjct: 3862 FFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ 3921
Query: 3894 -------ANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPISILQV 3941
N HL W+ LDK +E H +R+++S+ P P P IL+
Sbjct: 3922 VRGGQHCRNIHLVARWLGTLDKKLEHYST-GSHEDYRVFISAEPAPSPETHIIPQGILEN 3980
Query: 3942 SIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQL 4001
+IK+T EPP G+ AN+ + L ++ C+K ++K +LF+LC+FH+V+ ER+KF
Sbjct: 3981 AIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQ 4040
Query: 4002 GWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTY 4061
GWN Y FN+ D +S N+L YL+ + PWD L+YL I YGGH+TDDWDRRL TY
Sbjct: 4041 GWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTY 4100
Query: 4062 INDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVAS 4121
+ +Y + L + + IP + Y EYI + P +G HPNA++
Sbjct: 4101 LAEYIRTEMLEGD---VLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGF 4157
Query: 4122 QITEAQTLFDTLLSLQPQITPTRAG-GQTREEKV--------------LELAA------- 4159
++ LF T+L +QP+ T + AG G +REEK LEL
Sbjct: 4158 LTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTG 4217
Query: 4160 --------DVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLE 4211
D+ +KIPE + A + +P VV QE +R N L + SL +L
Sbjct: 4218 FQVKAVLDDILEKIPETFNMAEIM-AKAAEKTPYVVVAFQECERMNILTNEMRRSLKELN 4276
Query: 4212 KGIQGLIVMSTSLEEIFNCIFDAHVPPLW-GKAYPSQKPLAAWTRDLAMRVEQFELWASR 4270
G++G + ++T +E++ +F VP W +AYPS LAAW DL +R+ + E W +
Sbjct: 4277 LGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTD 4336
Query: 4271 ARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVW 4330
P WL+GF P FLTA++QS AR+N +D + V+ + ++ PP++G +
Sbjct: 4337 FALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSY 4396
Query: 4331 VRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY 4384
V GL++EGA WD + + EA +L MP I + + K +Y CP Y
Sbjct: 4397 VYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVY 4450
Score = 108 bits (270), Expect = 1e-22
Identities = 74/315 (23%), Positives = 147/315 (46%), Gaps = 16/315 (5%)
Query: 93 VWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWE 152
+ +E+ A+ F + P +L + ++ + LG P +++ VYFI+ I +
Sbjct: 31 IGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFPQSLKSKGVYFIKTKSENINKD 90
Query: 153 NFEATVQFGTVRGPYIPALLRLLGGVFAPQIFAN---TGWPESIRNHFASHLHKFLACLT 209
N+ A + +G + + L+ ++ V + + + GWP+ + +H+ +
Sbjct: 91 NYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMF 150
Query: 210 DTRYKLEGHTVLYIPA---------EAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML 260
K++G T+L IP E+M P + D L+ +ET++I W+ QI+++L
Sbjct: 151 VMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSL--DNLLLHAIETTIIDWSHQIRDVL 208
Query: 261 SAQETVETGENLGPLEEIEF--WRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPF 318
S + L PL ++EF W R ++L I +QL + V + IL AKS Y
Sbjct: 209 SKDSAQALLDGLHPLPQVEFEFWDTRLLNLKCIHEQLNRPKVNKIVEILEKAKSCYWPAL 268
Query: 319 MKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHY 378
+ + +G ++A + +L L+ +E+ + + + K++ I IW S +Y
Sbjct: 269 QNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPTFIAKVLDTICFIWATSEYY 328
Query: 379 NTRERLTSLFRKVCD 393
NT R+ + ++ C+
Sbjct: 329 NTPARIIVILQEFCN 343
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 2141 bits (5548), Expect = 0.0
Identities = 1249/3580 (34%), Positives = 1978/3580 (55%), Gaps = 139/3580 (3%)
Query: 923 PIQTV-----VEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRY 977
P+QT V ++++I K+ + +S+ + + + + + Y IW+ K+ I +
Sbjct: 1100 PVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTF 1159
Query: 978 QRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFAT 1037
+P +S F + I + + + E + + L + LKF+L W
Sbjct: 1160 ITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGR 1219
Query: 1038 LLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIHE 1097
+ + + ++E +K++RP + L+++ +++ + ++ + +++ Q+ PI E
Sbjct: 1220 HCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEE 1279
Query: 1098 QFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFK 1157
+A+L +Y + + ++ +D+L+ W + + L + FK LI + + F
Sbjct: 1280 SYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFL 1339
Query: 1158 KKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPS 1217
+ H D++ G S + A D++ + + + + +F +
Sbjct: 1340 QDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQY 1399
Query: 1218 KDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKE 1277
L ++K+L+ LQ+I+ + E N + + + E + R KL +
Sbjct: 1400 PQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRA 1459
Query: 1278 YKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLE 1337
KD W+ + I+ F PL+ + + A+ ERHW+++ D +ESF L
Sbjct: 1460 LKD--WQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLR 1517
Query: 1338 QIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRG-- 1395
I+E + ++ E+I +I SA KE IE L+ + WD +K +G LRG
Sbjct: 1518 NIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDS 1577
Query: 1396 TEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLEN 1455
T E+ +ED+ + L ++ ++R+ F+ + W + LS ++IE +TVQ W+YLE
Sbjct: 1578 TSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEA 1637
Query: 1456 IFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLI-EMNTILE 1514
+F+G DI KQLP E+ F ++ +W IM R ++ + ++ L L+ + LE
Sbjct: 1638 VFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLE 1697
Query: 1515 DIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKV 1574
QKSL YLE KR FPRF+F+S+ LLEILGQ+ + +Q HL FDNIK ++ +
Sbjct: 1698 ICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHE- 1756
Query: 1575 GGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRK 1634
+ + S +GE I+ V EG VE WL + + + +L ++R +++
Sbjct: 1757 ---KIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQE 1813
Query: 1635 FLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYS 1694
+ +++ + QV + Q+ WT D + L AK DKKI++ + + +LN
Sbjct: 1814 TGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAK--FDKKIMQKTNQAFLELLNTLI 1871
Query: 1695 EAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDC 1754
+ +L+ R+K L+TI +H RD+ + L + F+WL Q RFY+ +D D
Sbjct: 1872 DVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKM 1931
Query: 1755 VIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVK 1814
+I T+ F Y E+LG + RLVITPLTDRCY+TL AL + GG+P GPAGTGKTET K
Sbjct: 1932 MIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTK 1991
Query: 1815 DLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILC 1874
D+G+ LG YV+V NCS+ +D++ +GR++ GLAQ+G+WGCFDEFNRI++ VLSV A QI
Sbjct: 1992 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISI 2051
Query: 1875 ILSALAAGLTHFHF-DGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDS 1933
IL+ F F DG + + G+F+TMNPGYAGR ELPENLK FR +AM+VPD
Sbjct: 2052 ILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDR 2111
Query: 1934 TLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRL 1993
+I + L GF + +LA+K +TLY L +QLS+Q HYDFGLR + S+LR G +R
Sbjct: 2112 QIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRA 2171
Query: 1994 QPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIR 2053
P T+ +++ +RDMN++KL D PLF ++++DLFPNI L Y +L + +++
Sbjct: 2172 NPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVE 2231
Query: 2054 DMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFN 2113
+ GL + P KV QL+ET+ RH M +G +G+GKT L +++ G P+
Sbjct: 2232 EAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTD---CGKPH-- 2286
Query: 2114 IVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTL 2173
RE +NPKA++ +++G D++TN+WTDGI S++ R +K + WI+ DGPVD +
Sbjct: 2287 --REMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAI 2344
Query: 2174 WIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLG 2233
WIEN+NSV+DDNK LTL NG+RI M ++FE ++ ASPATVSR GMV+ + L
Sbjct: 2345 WIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILD 2404
Query: 2234 WKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGIT-SLCKLYS 2292
W P ++ +L+KR E E L++++ + + F N + + + E IT S+ L
Sbjct: 2405 WSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQG 2464
Query: 2293 ALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLR-------EIE 2345
+ E G GE + FVF+++WS A+++ +GR+R++ +LR E+
Sbjct: 2465 LIPLKEQG-----GEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELP 2519
Query: 2346 GSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNA-PFY-KIMVPTVDTVRYNYLVS 2403
DT ++Y+V P +WT + + + + YP + P Y I+VP VD VR ++L+
Sbjct: 2520 PPAGPGDTAFDYYVAPD-GTWTHWNTRT-QEYLYPSDTTPEYGSILVPNVDNVRTDFLIQ 2577
Query: 2404 SLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVE 2463
++ +LL+G GT KT I + + + +N S+ TT Q IES V+
Sbjct: 2578 TIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVD 2637
Query: 2464 KRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQ-TIKYI 2522
KR Y P GK M F+DD+NMP + +G Q E++R ++ +Y+ K I
Sbjct: 2638 KRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSI 2697
Query: 2523 REMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTM-----INQKLQDF 2577
++ +AAM PGGGR I RL+ +F+I N T P+++ + +IFG + Q+ F
Sbjct: 2698 VDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQR--GF 2755
Query: 2578 EEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTK 2637
EEV+ + T ++ + LPTP K HY+FNLRD+S+V+QGML +
Sbjct: 2756 SEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEP 2815
Query: 2638 SSITRLWIHECFRVFSDRLVDAADT----EAFMGIISDKLGSFFDLTFHHLCPSKRPPIF 2693
+ + +LW HEC RV +DR ++D +A + ++ ++ G L L F
Sbjct: 2816 NDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKL----LVDCGIDTYF 2871
Query: 2694 GDFLKE----------------PKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLF 2737
DFL++ PK+YE + + LK + L YN S M +V F
Sbjct: 2872 VDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFF 2931
Query: 2738 REAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEF 2797
+A+ H+ +I RVI P+GN LLVG+GGSG+QSL RLAS I Y +FQI +T+ Y
Sbjct: 2932 ADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNL 2991
Query: 2798 RDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSH 2857
+D+K LYR AG + K +FIF D +I DESFLE +NN+LSSGEV NL+ DE +EI S
Sbjct: 2992 MEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSD 3051
Query: 2858 IIDQARVE--QVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTI 2915
+ + E + ++++L Y + RV+ NLHIVLC SP+G+ FRN ++PAL++ TI
Sbjct: 3052 LASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTI 3111
Query: 2916 NWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHN 2975
+WFS WP++AL+ V+E L D+ I ++V Q + VA+ RR
Sbjct: 3112 DWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRST 3171
Query: 2976 YVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKV 3035
+VTP YL + GYK + GEK E+ AN++ TGL K+ E E V +S ELE AK+K
Sbjct: 3172 HVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELE-AKEKE 3230
Query: 3036 AEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK--CQALADNAQKD------ 3087
+ + ++ V K +A E+ KA V+++K QA+ D+ KD
Sbjct: 3231 LQVANDKADMVLKEVTMKAQAAEKVKA--------EVQKVKDRAQAIVDSISKDKAIAEE 3282
Query: 3088 -LEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNE--------- 3137
LE A PALEEA AL+++ DI +++ GRPP + +M V++L +
Sbjct: 3283 KLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLE 3342
Query: 3138 -----PTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLA 3192
P+W E+ + + NF+++L F KD I+++V++ + Y PD+ + RV
Sbjct: 3343 KSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGN 3402
Query: 3193 AKSLCMWVRAMELYGRLYRVVEPKR----IRMNAALAQLREKQAALAEAQEKLREVAEKL 3248
LC W +AM + + + V P + ++ N L +++ Q A AE +K E L
Sbjct: 3403 VAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAE----L 3458
Query: 3249 EMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLV 3308
++++ +Y++ + +K+ L + +E K++ A L+SGLAGEK RW E Q LV
Sbjct: 3459 DVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLV 3518
Query: 3309 GDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWN 3368
GD LLA AFLSY GPF +RD ++N W ++ ++P + + L + + +WN
Sbjct: 3519 GDVLLATAFLSYSGPFNQEFRDLLLND-WRKEMKARKIPFGKNLNLSEMLIDAPTISEWN 3577
Query: 3369 IQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRIL 3428
+QGLP+D S +NGIIVT+ +R+ L+IDPQ Q WIKN E L+I L + L
Sbjct: 3578 LQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHL 3637
Query: 3429 EHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTK 3488
E ++ G P+L+++V E LDP L+ +L ++ + G +++GDKEV+ FR YITTK
Sbjct: 3638 EDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTK 3697
Query: 3489 LSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKL 3548
L NP Y+PE SA+T+I++F V +GLE QLLG V+ E+ ELE+++ L+ ++ A KR++
Sbjct: 3698 LPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRM 3757
Query: 3549 KELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYR 3608
KELED +L L GSL++D L+ L +K TA EVT++LE S TE+ + ARE YR
Sbjct: 3758 KELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYR 3817
Query: 3609 PCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTY 3668
P A R SIL+F++ +M ++ MYQ SL ++ LF LS+ +S +S RI + ++ TY
Sbjct: 3818 PVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTY 3877
Query: 3669 AVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSS 3728
VY+Y R L+E HK LF+ + KI ++ +E+ ++GG LD + P S
Sbjct: 3878 EVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKP-SK 3936
Query: 3729 WLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQR 3788
W+ D W N+ EL KL F +++ + + W +W+ PE+ LP ++ + + +R
Sbjct: 3937 WILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRR 3996
Query: 3789 MLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPT 3848
+L++RS DR +I+ ++G ++ E +L+++ E+S PR+PL+ +LS G DPT
Sbjct: 3997 LLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPT 4056
Query: 3849 SALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDK 3908
+++ L + + + R+ +S+GQGQ A +LL++ + G W L NCHL L +M L
Sbjct: 4057 DSIIALGKRLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMD 4114
Query: 3909 LVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQ 3968
++ ++ E H +FRLW+++ H FPI++LQ+SIK +PP+GL+A + R Y +S+
Sbjct: 4115 II--IETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDL 4172
Query: 3969 FSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEY 4028
S +++K +L+++ F HS + ER+KF LGWNI Y FN +DF + + +LD+
Sbjct: 4173 LD-VSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDM 4231
Query: 4029 E---ETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYF 4085
+ W ++Y+I I YGG VTDD+D+RLL T+ +F + F S + Y
Sbjct: 4232 DVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDF---SFYQGYN 4288
Query: 4086 IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRA 4145
IPK ++ +Y +YI LP D PE FG HPNAD+ Q A+ + DT+L +QP+ T +
Sbjct: 4289 IPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDT-SGG 4347
Query: 4146 GGQTREEKVLELAADVKQKI-PEMIDYEGTQKLLALDP-SPLNVVLLQEIQRYNTLMQTI 4203
G +TRE V LA D+ +K+ P+ + +E ++L + P P+N+ L QEI R ++ +
Sbjct: 4348 GDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLV 4407
Query: 4204 LFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQ 4263
+LT+L+ I G I+MS +L + +C+FDA +P W KA L W +L R Q
Sbjct: 4408 RSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISSTLGFWFTELIERNSQ 4467
Query: 4264 FELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQN-NVSVDSLSWEFIVSTVDDSNLV 4322
F W RP FW++GF P GFLTA+ Q R N ++D++ V+ ++
Sbjct: 4468 FTSWVFNGRPH-CFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDIS 4526
Query: 4323 YPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCP 4382
PP +GV+V GLYLEGAGWD++N L+E++P L LMP I AE+ YSCP
Sbjct: 4527 APPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSCP 4585
Query: 4383 CYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALL 4422
Y P R +++ +DLR+ A TP+HW+ RG ALL
Sbjct: 4586 IYKKPVRTD----LNYIAAVDLRT-AQTPEHWVLRGVALL 4620
Score = 97.8 bits (242), Expect = 2e-19
Identities = 78/284 (27%), Positives = 138/284 (48%), Gaps = 22/284 (7%)
Query: 129 GMPVQTQNQLVYFIRQAPVP-ITWENFEATVQFGTVR---GPYIPALLRLLGGVFAPQIF 184
G V V+FIR P IT +N V F + G + ++ RLL +F P +
Sbjct: 118 GNDVALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALR 177
Query: 185 ANT-GWPE--------SIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEM- 234
A + GW E +IR F S L F+ L+ + L+ L + + +K
Sbjct: 178 ATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLR-KCDILELKTLKE 236
Query: 235 ------VIKDKELVQRLETSMIHWTRQIKEMLSAQ-ETVETGENLGPLEEIEFWRNRCMD 287
+ + E + ++E M W +Q +++L+ + ++ +++GP E+E W+ R
Sbjct: 237 PTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSK 296
Query: 288 LSGISKQLVKKGVKHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQ 347
+ + +QL VK V ++L AKS L + ++ +I D + +A+ N+ +L L++
Sbjct: 297 FNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCD 356
Query: 348 ELAFMKPKDISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKV 391
L P + +P LI+ I++I+ S +YNT E++TSLF KV
Sbjct: 357 PLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKV 400
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/291 (19%), Positives = 117/291 (40%), Gaps = 7/291 (2%)
Query: 437 TLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFH 496
T++ LD + + +DY +F DL + + F +++ + +L F
Sbjct: 517 TIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFE 576
Query: 497 RLASREAIKRTYDKKAVDLYMLFNSELALVNR--ERNKKWPDLEPYVAQYSGKARWVHIL 554
RL D K + + +++ ++++ + K P L +GK W L
Sbjct: 577 RL---NIPNLGIDDKYQLILENYGADIDMISKLYTKQKYDPPLARNQPPIAGKILWARQL 633
Query: 555 RRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDKDCIRRL 614
RI + M + K + +Y +M + + E + W +++ + L
Sbjct: 634 FHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVG-L 692
Query: 615 DTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILREN 674
+ LL + G L VNFD +LILF E + ++ E ++ ++ + + N
Sbjct: 693 EASLL-VKAPGTGELFVNFDPQILILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSN 751
Query: 675 LLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAF 725
+ ++ +Y R+ + + + L + +D+ + PGL L W A+
Sbjct: 752 MKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAY 802
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 2130 bits (5519), Expect = 0.0
Identities = 1464/4608 (31%), Positives = 2311/4608 (50%), Gaps = 359/4608 (7%)
Query: 53 EEPEPRLEGPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQ-----EHDAILEHFAQ 107
EE E E A+ S +A V+ L A + G + W+Q ++ +L F +
Sbjct: 36 EEEEENEEEAAARRARSFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLE 95
Query: 108 DPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPY 167
+ + L L +P ++LV+ ++ I +F V FG +
Sbjct: 96 STSPACLVFSFAASGRLAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALS 155
Query: 168 IPALLRLLGGVFAPQIFANTG---WPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIP 224
+ + L + P + W H+ + R K+ T+L IP
Sbjct: 156 LGHVSAFLDEILVPVLSNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIP 215
Query: 225 AEAMNMKPEMVIKDKE-------LVQRLETSMIHWTRQIKEMLSAQ--ETVETGENLGPL 275
A M + + + ++ +E+ +I W+ QI+E++ + + G +L P
Sbjct: 216 TVAGKMDLDQNCSENKPPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQ 275
Query: 276 EEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMKL----------AQQI 325
E++FW R +LS I QL V + IL +SSY + AQ +
Sbjct: 276 AELDFWMMRRENLSCIYDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDV 335
Query: 326 QDGSRQAQSNLTFLSILKEPY--------------------------------------- 346
+ R + ++ L + P
Sbjct: 336 ELYLRPLRRHIQCLQETEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLF 395
Query: 347 --QELAFMKPKD-----ISSKLPKLISLIRIIWV-NSPHYNTRERLTSLF--RKV--CDC 394
Q A++ P+D I L K+ + I+ + +N R++L S F RK+ D
Sbjct: 396 INQATAYLSPEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDF 455
Query: 395 QYH--FARWEDGKQGPLPCFFGAQGPQITRNLLEIEDIFHKNLHTLRAVR-------GGI 445
Q H F R++ + L++IEDIF L + R G I
Sbjct: 456 QSHLVFCRFD----------------KFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAI 499
Query: 446 L--------------------------DVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAF 479
L D N + DY F++ + + +I AF
Sbjct: 500 LNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAF 559
Query: 480 ELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE- 538
+ LL F + + + L +FN+EL + + N+ +E
Sbjct: 560 FNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHMKQIEC 619
Query: 539 ---------PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESV--HTYQQM 587
P+ SG +W + +R+ + A +L +G ++ Y +M
Sbjct: 620 GHVVLNKNMPFT---SGNMKWAQQVLQRLQMFWSNFASLRYL-FLGNPDHALVYQKYVEM 675
Query: 588 VQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYW 647
+D+ + + EW S++D+ C L+ PL++ S G+L VNFD L+ + E+ Y
Sbjct: 676 TTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAIN-GLLCVNFDPKLVAVLREVKYL 734
Query: 648 ERLLFET-PHYVVNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDK 706
L + P + + ++ + NL L+ + YN++ L E L ++ +R +D+
Sbjct: 735 LMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRAIDE 794
Query: 707 KIHPGLKKLHWALKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRI 766
++ L W +C + +V +A+T + R + + + V
Sbjct: 795 QLTAATTWLTWQ---------DDCWGYIERV-------RAATSELEHRVERTQKNVKVIQ 838
Query: 767 SGKRVYRDLEFEEDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQ------- 819
R + +REHR L +D + T Y++ + DG +I
Sbjct: 839 QTMRGWARCVLPP-RREHRREAAFTL----EDKGDLFTKKYKLIQGDGCKIHNLVEENRK 893
Query: 820 ---------QWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPNPLFQVLVILK 870
W +Y+ +D ++ + + L K N + + P P FQ +IL
Sbjct: 894 LFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLK--NTEKQLKPAPFFQAQMILL 951
Query: 871 NDLQGSVAQVEFSPTLQTLAG--VVNDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVV 928
++ F P+L AG + + L ++ + + I T ++ Q +
Sbjct: 952 PP------EIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKN--YQNDM 1003
Query: 929 EQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFV 988
+ + +++ +I + + N + + ++ T + + +W ++ F+ + VSS
Sbjct: 1004 DNMLGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDE 1063
Query: 989 ADIARYTEVANNV----QKEETVTNIQFVLL-----------------DCSHLKFSLVQH 1027
D E+ Q +E + + + + D K SL+
Sbjct: 1064 MDAHANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTI 1123
Query: 1028 CNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLAN 1087
+W F L L EL ++KE + R + G LVD + H LA
Sbjct: 1124 IKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDG----LVDIMVHLLAV 1179
Query: 1088 VETQ------IPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKH 1141
Q P+ E +LE Y + + V L+ L W ++ + +
Sbjct: 1180 RSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPL 1239
Query: 1142 KEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNV-GYMSALDQITQVRAMLMAMREEE 1200
T + F K E F N +ALD+ + L A+ EE
Sbjct: 1240 HNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEE---LEALEEEM 1296
Query: 1201 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEI---ARDWEENWN--EWKTGRFLIL 1255
++ + +F++ P K ++ KE+ L+ +W++ R +NW +W+ +
Sbjct: 1297 LQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQM 1356
Query: 1256 QTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERH 1315
E + L KE R W+ ++ ++ I++L++PALR+RH
Sbjct: 1357 DVELRRFAKASSITEIWSLNKEV--RVWDAYTGLEGTVKDMTASLRAITELQSPALRDRH 1414
Query: 1316 WDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTW 1375
W Q+ I +F +E+ TL ++ L + + + + I A KEL E + I++TW
Sbjct: 1415 WHQLMKAIGVKF-LINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTW 1473
Query: 1376 DVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSL 1435
+ + G L+ E++F+ LE NQV L T+ S++V+ F + V W+ L++
Sbjct: 1474 ATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNI 1533
Query: 1436 ILEVIEMILTVQRQWMYLENIFL-GEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNAL 1494
VI + VQR W +LE+IF+ EDIR QL ++ FD V++ +K +M + K N L
Sbjct: 1534 ADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVL 1593
Query: 1495 RSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEA 1554
+T P L + L ++ + L +K+L YLETKR FPRFYF+S+ DLL+IL + P+
Sbjct: 1594 EATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQ 1653
Query: 1555 VQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVE 1614
V HL K FD+I L+ + S+ AVGM+S + EY+ F G VE+WL +E
Sbjct: 1654 VTCHLAKLFDSIADLQFEDNQDVSAH-RAVGMYSKEKEYVPFQAECECVGHVETWLLQLE 1712
Query: 1615 QTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERA 1674
QTM+ T+R + +A + R+ W+ ++ QV +T+SQI WT DV + E
Sbjct: 1713 QTMQETVRHSITEAIVAYEE--KPRELWIFDFPAQVALTSSQIWWTTDVG-IAFSRLEEG 1769
Query: 1675 DKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLY--KSGLM 1732
+ LK K Q+S LN + G L R KI+ + TI++HARDV+ KL K ++
Sbjct: 1770 YETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVV 1829
Query: 1733 DVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTA 1792
+F WLSQLR WE C + + QFQY YEYLGNS RLVITPLTDRCY+TLT +
Sbjct: 1830 SPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQS 1889
Query: 1793 LHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWG 1852
LHL G+P GPAGTGKTET KDLG+ALG+ V V NCSE +DYKS+G +Y GL QTGAWG
Sbjct: 1890 LHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWG 1949
Query: 1853 CFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGR 1912
CFDEFNRI++EVLSVVA Q+ I A+ F F G I L S GIFITMNPGYAGR
Sbjct: 1950 CFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGR 2009
Query: 1913 TELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDH 1972
TELPENLK++FRP AMV PD LI EI+L EGF + + LA+K TLY+L + LS+QDH
Sbjct: 2010 TELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDH 2069
Query: 1973 YDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFP 2032
YD+GLRA+ S+L AG +R + +++VL+ ++RD N+ K+ + D P+F +V DLFP
Sbjct: 2070 YDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFP 2129
Query: 2033 NIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTA 2092
+++P + V Q ++ LQ + KV QL E RHS +VG G+GK+
Sbjct: 2130 ALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSK 2189
Query: 2093 SWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTD--------- 2143
R L + ++ + P +N LNPKA++ EL+G +T EW D
Sbjct: 2190 ILRTLNRTYVNMKQ--KPVWN-----DLNPKAVTTDELFGFIHHATREWKDGKIVYSYFI 2242
Query: 2144 GILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVS 2203
G+ SS++R + KWI+ DG +D +WIE++N+VMDDNKVLTL + ERIA+ +
Sbjct: 2243 GLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMR 2302
Query: 2204 LLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLE-KRPKAEVEPLQRMFEKLIN 2262
LLFE+ L A+PATVSR G++Y + DLGW PYV SW++ +R ++E L +F+K +
Sbjct: 2303 LLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVP 2362
Query: 2263 KMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMI 2322
L + + K + +PE S + +LC L L TPEN + + E Y E+ FVF+ I
Sbjct: 2363 ACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSDSPKEVY----EVYFVFACI 2418
Query: 2323 WSVCASVDEEGRKRIDSYLREIEG---------SFPNKDTVYEYFVDPKIRSWTSFEDKL 2373
W+ ++ ++ +I Y + FP++ T+++Y+VD K + + DK+
Sbjct: 2419 WAFGGTLLQD---QISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKI 2475
Query: 2374 PKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSL 2433
+ + P+ P ++V T +T R Y + L+ P++LVG G GKT L SL
Sbjct: 2476 AQ-FTMDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASL 2534
Query: 2434 PSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMF 2493
S + V V + TTS +Q I+E +EK+ Y P G K +I F+DD+NMP D++
Sbjct: 2535 -SEDYIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLY 2593
Query: 2494 GSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIIN 2553
G+ P LIR IDYG WYDR K +K I +A M P G T I+PRL+ F +
Sbjct: 2594 GTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFA 2652
Query: 2554 MTFPTKSQIIRIFGTMINQKLQD--FEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMH 2611
FP+ + I+G + + Q F + G + +AT+ + T++ FLPT K H
Sbjct: 2653 FNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFH 2712
Query: 2612 YLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFMGIISD 2671
Y+FNLRD+S VFQG+L A+ + + LW+HE RV+ D+L+D D + F + +
Sbjct: 2713 YIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLE 2772
Query: 2672 KLGSFFDLTFHHLCPSKRPPI---FGDFLKEPKVYEDLTDLTVLKTVMETALNEYNLSPS 2728
+F+ H+ ++P I F D K+P Y + D VLKT++ L+ YN +
Sbjct: 2773 TAYKYFEGIDSHML-LQQPLIYCHFADRGKDPH-YMPVKDWEVLKTILTETLDNYNELNA 2830
Query: 2729 VVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEV 2788
M LVLF +A++H+ RI R++ P+G LLVG+GGSG+QSL+RLA+ + FQI +
Sbjct: 2831 A--MHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITL 2888
Query: 2789 TKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKP 2848
T+ Y QE R D+ LY + G + T F+ D Q+ DESFL IN++L+SGE+P+L+
Sbjct: 2889 TEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSD 2948
Query: 2849 DEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPA 2908
++ ++I S I ++ + +S ++ + + + RV+ L I+LC SP+G R R++PA
Sbjct: 2949 EDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPA 3008
Query: 2909 LVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVT-MHWSVAQYSQKM 2967
+VNCT I+WF WPQEAL+ V+ + + + E +H+ +F+ +H +V + S +
Sbjct: 3009 IVNCTAIDWFHAWPQEALVSVSRRFI--EETKGIEPVHKDSISLFMAHVHTTVNEMSTRY 3066
Query: 2968 LLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKV------ 3021
RRHNY TP +LE +S +K LL +K+ E+ + +L G+ K+ T +V
Sbjct: 3067 YQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKAR 3126
Query: 3022 ---QVMSLEL--EDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK 3076
Q L+L DA+ + + Q E+ + ++K AD +++ VTA ++ ++ +
Sbjct: 3127 LASQEAELQLRNHDAEALITKIGLQTEK----VSREKTIADAEERKVTAIQTEVFQKQRE 3182
Query: 3077 CQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMIL--- 3133
C+A DL +A PAL A AL +LN+ ++ E+K++ PP V V AVM+L
Sbjct: 3183 CEA-------DLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAP 3235
Query: 3134 RGNEP---TWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGA-YCAQPDFQPDIIGR 3188
RG P +W AK +G+ +F+++LIN+DK++I + LK + Y P+F P++I
Sbjct: 3236 RGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRT 3295
Query: 3189 VSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKL 3248
S AA LC WV + + +Y VEPKR + A +L L ++KL ++ L
Sbjct: 3296 KSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNL 3355
Query: 3249 EMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLV 3308
L +++ A+K +++ + ++ A LV L +K RW ++++ E L
Sbjct: 3356 SRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLC 3415
Query: 3309 GDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWE-LQVPCSPSFAIDNFLCNPTKVRDW 3367
GD LL AAF+SY+GPF YR E+V+ W+ + + + +P + + + L + + W
Sbjct: 3416 GDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAW 3475
Query: 3368 NIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRI 3427
N +GLPSD STEN I+T RW L+IDPQ Q +KWIKN + G LK+ L +L
Sbjct: 3476 NNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNA 3534
Query: 3428 LEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITT 3487
+E A+ FG +L++N++E +DP L+P+L ++ + G +RIGDKE E+N NFR + T
Sbjct: 3535 IETALAFGDVILIENLEETIDPVLDPLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHT 3592
Query: 3488 KLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRK 3547
KL+NPHY PE A+TT++NF V E GLEAQLL VV ERP+LE+ K L + K +
Sbjct: 3593 KLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIE 3652
Query: 3548 LKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAY 3607
LK LED++L L+ A GS LDD +LV L +K T E+ ++ ++ E + ARE Y
Sbjct: 3653 LKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECY 3712
Query: 3608 RPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHT 3667
RP A RAS+L+FV+ND+ I+P+YQFSL A+ LF +I+++ + ++ RI L + T
Sbjct: 3713 RPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESIT 3772
Query: 3668 YAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCS 3727
+AV+ YT + LFE+ KL F M +IL +++ E +F LR V +D
Sbjct: 3773 HAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVD---- 3828
Query: 3728 SWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQ 3787
+L W I + + F G+ E + W W + PEK LP EW+ + +Q
Sbjct: 3829 -FLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQ 3886
Query: 3788 RMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDP 3847
+++++R++R DR+ + + +F+ LG++++E L++ E+S+P +P+ FILSPGVD
Sbjct: 3887 KLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDA 3946
Query: 3848 TSALLQLAEHMGM---AQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMP 3904
L L + +G + +FH +SLGQGQ +A L + GHWV L N HL W+
Sbjct: 3947 LKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLG 4006
Query: 3905 NLDKLVEQLQVEDPHPSFRLWLS--SIPHPD---FPISILQVSIKMTTEPPKGLKANMTR 3959
L+KL+E+ + H +R+++S S P PD P +L+ SIK+T EPP G+ AN+
Sbjct: 4007 TLEKLLERFS-QGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHA 4065
Query: 3960 LYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSEN 4019
+ CSK ++K +LFSLC+FH+ + R +F GW+ Y FN D + +
Sbjct: 4066 ALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICAS 4125
Query: 4020 LLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLS 4079
+L YL+ + PW+ L+YL I YGGH+TDDWDR+L Y+ + F + SL+ L
Sbjct: 4126 VLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEE-FMNPSLTE--DELM 4182
Query: 4080 ALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQ 4139
+ P A Y +YI + + P +G HPNA++ + TLF TLL +QP+
Sbjct: 4183 LAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPR 4242
Query: 4140 ITPTRAG-GQTREEKVLELAADVKQKIPEMIDY-EGTQKLLALDPSPLNVVLLQEIQRYN 4197
+ GQ+ EEKV + D+ +K+PE + E QK + SP +V QE +R N
Sbjct: 4243 NALSGDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQK--NSNRSPYVLVCFQECERMN 4300
Query: 4198 TLMQTILFSLTDLEKGIQGLIVMSTSLE-EIFNCIFDAHVPPLWGK-AYPSQKPLAAWTR 4255
L++ I SL L+ ++G + +S ++E + F +D VP W K AYPS LA W
Sbjct: 4301 ILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDT-VPDTWSKLAYPSTYGLAQWFN 4359
Query: 4256 DLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVST 4315
DL +R + + W P + WLSGF P FLTA++Q+ AR+N +D V+
Sbjct: 4360 DLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTK 4419
Query: 4316 VDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSA 4375
+ +PP++G ++ GL++EGA WD + +VEA +L C MP I + ++
Sbjct: 4420 KTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQET 4479
Query: 4376 KGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLM 4423
K Y CP Y R S++ L+S T W+ G ALL+
Sbjct: 4480 KQTYECPVYRTKLRG-----PSYIWTFRLKSEEKTA-KWVLAGVALLL 4521
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 2087 bits (5406), Expect = 0.0
Identities = 1308/4145 (31%), Positives = 2141/4145 (51%), Gaps = 233/4145 (5%)
Query: 445 ILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAI 504
ILD + T + D+ F I LEV Q + S+F + + LL F +L + +
Sbjct: 414 ILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKL-NIPCL 472
Query: 505 KRTYDKKAVDLYMLFNSELALVNR--ERNKKWPDLEPYVAQYSGKARWVHILRRRIDRVM 562
+ + + +EL + K P L + +GK WV L RRI +
Sbjct: 473 GLEINHTIERILQYYVAELDATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPI 532
Query: 563 TCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDK-------------- 608
+ GK + Y ++ + E W + +
Sbjct: 533 NYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIREISQLHYALQATLFVRHP 592
Query: 609 ---DCIRRLDTPLLRISQEKAGMLDVNFD-----KSLLILFAEI-----------DYWER 649
+ D +L + +E M+ + D K LL L +++ Y++
Sbjct: 593 ETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDE 652
Query: 650 LLFETPHYVVNV---------AERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKER 700
L E P VN+ + + L +L + L + + + +L Q L K+
Sbjct: 653 LCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEVELVLDMFNQ-LLKKI 711
Query: 701 IRLLDKKIHPGLKKLHWALKGASAFFITECRIHASKVQ--MIVNEFKASTLTIGW----- 753
L + I LK++ A I+ A+KV+ + +NE T T W
Sbjct: 712 SDLCEMHIDTVLKEI------AKTVLISLPESGATKVEDMLTLNE----TYTKEWADILN 761
Query: 754 -RAQEMSEKLLVRISGKRVYRDLEF------EEDQREHRAAVQQKLMNLHQDVVTIMTNS 806
+++ + E + IS ++++ + +QR+H + + D + N
Sbjct: 762 HKSKHVEEAVRELISIFEQIYEVKYTGKVGKQSEQRKHVVFGSETGEGENNDYEANIVNE 821
Query: 807 YEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPNPLFQVL 866
++ + E +++ + D+L+ + SL + + I ++
Sbjct: 822 FDTHDKED-EFKKECKEVFAFFSHQLLDSLQKATRLSLDTMKRRIFVASLYGRKQSEDII 880
Query: 867 VILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCH------------LPDIL 914
+K+++ ++ V P+L + +N + H +P
Sbjct: 881 SFIKSEVHLAIPNVVMIPSLDDIQQAINRMIQLTLEVSRGVAHWGQQQIRPIKSVIPSPT 940
Query: 915 TKRKLHREPIQTV----------------------VEQDEDIKKIQTQISSGMTNNASLL 952
T H+ + + V + +DI K+ +SS + +
Sbjct: 941 TTDVTHQNTGKLLKKEERSFEEAIPARKLKNFYPGVAEHKDISKLVLLLSSSVNSLRKAA 1000
Query: 953 QNYLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQF 1012
L+ + Y+ +W ++D + + NP ++ ++I Y + + + + +
Sbjct: 1001 HEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYATFEQEIDELKPIIVVGA 1060
Query: 1013 VLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELG 1072
+ L +K +L W+ L E ++ + ++ E +K+SRP + L+++
Sbjct: 1061 LELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYLKKLSRPIRDLDDVR 1120
Query: 1073 VSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLL 1132
+++ + ++ + ++ + PI E +AIL ++EV V E +D+L + Q +
Sbjct: 1121 FAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAV 1180
Query: 1133 DSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAM 1192
++ L + + KFK+ L+ S + F++ E +E +G N+ A +++ +A
Sbjct: 1181 SVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEASNRLQIFQAS 1240
Query: 1193 LMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIW--------EIARDWEENW 1244
+ + + + +F + + L KEL+ LQ+++ I+ +E W
Sbjct: 1241 FDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILW 1300
Query: 1245 NEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLIS 1304
+ + E + R KL K KD W+ + +I+ F + PL+
Sbjct: 1301 GD--------VDIEKINAELLEFQNRCRKLPKGLKD--WQAFLDLKKRIDDFSESCPLLE 1350
Query: 1305 DLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAI 1364
+ N A+++RHWD++ + FD ES+SF L I+E + +H + I +I SA KE I
Sbjct: 1351 MMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDI 1410
Query: 1365 EVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTE--EVFQALEDNQVALSTMKASRFVKAF 1422
E L + + W L +K KG L+GTE E+ +ED+ + L ++ ++R+ F
Sbjct: 1411 EAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1470
Query: 1423 EKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKA 1482
+K++ +W LS ++IE L VQ W+YLE +F+G DI KQLP E+ F ++ +W
Sbjct: 1471 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1530
Query: 1483 IMDRMNKDNNALRSTHHPGLLDTLI-EMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDD 1541
IM R +++ N + + L+ ++ LE QKSL YLE KR +FPRF+F+S+
Sbjct: 1531 IMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPV 1590
Query: 1542 LLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAV-GMFSGDGEYIDFLHSV 1600
LLEILGQ+ + +QPHL DNI +V + ++ + + S +GE I +SV
Sbjct: 1591 LLEILGQASDSHTIQPHLPAVSDNIN-----EVTFHAKDYDRIMAVISREGEKIVLDNSV 1645
Query: 1601 FLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWT 1660
+GPVE WL D+ + +L +++R+ + + ++ + QV + Q+ WT
Sbjct: 1646 MAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWT 1705
Query: 1661 ADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHAR 1720
D + L AK+ D+KI++V + + ILN +L+K R+K L+TI +H R
Sbjct: 1706 HDSEEALRNAKD--DRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQR 1763
Query: 1721 DVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITP 1780
D+ + L K + F+WL Q RFY+++DLD V+ T+ F Y E+LG + RLVITP
Sbjct: 1764 DIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITP 1823
Query: 1781 LTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGR 1840
LTDRCY+TL AL ++ GG+P GPAGTGKTET KD+G+ LG YV+V NCS+ +D++ +GR
Sbjct: 1824 LTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGR 1883
Query: 1841 MYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHF-DGFEINLVWSC 1899
++ GLAQ+G+WGCFDEFNRI + VLSV A QI +L+A F F DG ++L
Sbjct: 1884 IFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEF 1943
Query: 1900 GIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTL 1959
GIF+TMNPGYAGR ELPENLK FR +AM+VPD +I + L GF ILA+K Y L
Sbjct: 1944 GIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVL 2003
Query: 1960 YSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVD 2019
Y L +QL++Q HYDFGLR + S+LR G ++R +P+ ++ +++ +RDMN++KL D
Sbjct: 2004 YKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDED 2063
Query: 2020 APLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHS 2079
PLF +++ DLFP ++L Y +L+ V +++ GL + P K+ QLYET RH
Sbjct: 2064 EPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHG 2123
Query: 2080 TMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTN 2139
M +G +GSGKT IL + + G P+ RE +NPKA++ +++G D +TN
Sbjct: 2124 LMTLGPSGSGKTTVITIL---MKAQTECGRPH----REMRMNPKAITAPQMFGRLDTATN 2176
Query: 2140 EWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMP 2199
+WTDGI S++ R +K + +++ DGPVD +WIEN+NSV+DDNK LTL NG+RI M
Sbjct: 2177 DWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2236
Query: 2200 EQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEK 2259
LLFEV ++ ASPATVSR GMVY + L W+P +Q+WL+KR E ++EK
Sbjct: 2237 PSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRTAQEAAVFLTLYEK 2296
Query: 2260 LINKMLAFKKDNCKELVPLPEYSGIT-SLCKLYSALATPENGVNPADGENYVTMVEMTFV 2318
+ + K N + L E + I SL L + + E G G + V + FV
Sbjct: 2297 VFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEG-----GVSCVEHLHKLFV 2351
Query: 2319 FSMIWSVCASVDEEGRKRIDSYLREIEGSFP-------NKDTVYEYFVDPKIRSWTSFED 2371
F ++WS+ A ++ E R++++++LR+ E + T+YE++V W +
Sbjct: 2352 FGLMWSLGALLELESREKLEAFLRQHESKLDLPEIPKGSNQTMYEFYVTD-YGDWEHWNK 2410
Query: 2372 KLPKSWRYPPNAPFYK-IMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVL 2430
KL + + P Y I+VP VD +R N+L+ ++ +LL G GT KT + ++ L
Sbjct: 2411 KLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYL 2470
Query: 2431 QSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAK 2490
+ +N S+ T Q IES V+KR Y P GG+ M F+DD+NMP
Sbjct: 2471 KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVI 2530
Query: 2491 DMFGSQPPLELIRLWIDYGFWYDRTKQ-TIKYIREMFLMAAMGPPGGGRTVISPRLRSRF 2549
+ +G Q E++R ++ Y K I ++ L+AAM PGGGR I RL+ +F
Sbjct: 2531 NEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQF 2590
Query: 2550 NIINMTFPTKSQIIRIFGTM---INQKLQDFEEEV-KPIGNVVTEATLDMYNTVVQRFLP 2605
+ N T P+ + I +IFG + + F+ ++ + I N+V+ + ++ + LP
Sbjct: 2591 TVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVGRV-LWQWTKVKMLP 2649
Query: 2606 TPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAF 2665
TP+K HY+FNLRD+S+++QGML + + ++ L+ HEC RV +DR + D + F
Sbjct: 2650 TPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWF 2709
Query: 2666 MG----IISDKLGSFFDLTFHHLCPSKRPPIFGDFLKE----------------PKVYED 2705
+ + +GS + P P F DFL+E PK+YE
Sbjct: 2710 NAHLTRAVEENIGSD---AASCILPE---PYFVDFLREMPEPTGDEPEDSVFEVPKIYEL 2763
Query: 2706 LTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGG 2765
+ L ++ ++N + LV F++A+ H+ +I R+I GN LLVG+GG
Sbjct: 2764 MPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGG 2823
Query: 2766 SGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIA 2825
SG+QSL+RLAS I Y FQI +T+ Y DD+K LY+ AG + K +FIF D++I
Sbjct: 2824 SGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIK 2883
Query: 2826 DESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVE--QVPESSDSLFAYLIERVQ 2883
DE+FLE +NN+LSSGE+ NL+ DE +EI +I + E + P + D+L+ Y I R +
Sbjct: 2884 DEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFDNLYEYFISRSR 2943
Query: 2884 NNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQE 2943
NLH+VLC SP+G+ FR ++P L++ T++WFS WP+EAL+ VA L ++
Sbjct: 2944 KNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSS 3003
Query: 2944 NIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQ 3003
I R+V + H V++ + RR +VTP YL ++GYK + EK + + Q
Sbjct: 3004 EIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQ 3063
Query: 3004 ANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLV---IIVQQKREADEQQ 3060
A ++ GL K+ E E V +S +L +K++A + +E L + Q + +
Sbjct: 3064 AERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEV 3123
Query: 3061 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP 3120
+ V ++KI V+EI + + A+ LE A PALEEA AL ++ DI ++ +PP
Sbjct: 3124 QEVKDKAQKI-VDEIDSEKV--KAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPP 3180
Query: 3121 AQVEIVMQAVMILRGNE--------------PTWAEAKRQLGEQNFIKSLINFDKDNISD 3166
+ +M V++L + P+W E+ + + F+ SL F KD I++
Sbjct: 3181 HLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINE 3240
Query: 3167 KVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQ 3226
+ ++ + Y D+ + +V L W AM ++ + R V P + + +
Sbjct: 3241 ETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGR 3300
Query: 3227 LREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGL 3286
L A L +AQ L E +L+ ++ ++D + +K +L ++ K++ A L+ GL
Sbjct: 3301 LAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGL 3360
Query: 3287 AGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQV 3346
+GEK RW + + + + LVGD LL FLSY+GPF +R+ ++ W ++ ++
Sbjct: 3361 SGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKI 3420
Query: 3347 PCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIK 3406
P + + + + L +P + +W +QGLP D S +NGIIVT+ R+ L+IDPQ Q WIK
Sbjct: 3421 PFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIK 3480
Query: 3407 NMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRL 3466
+ E L++ L + LE ++ G P+L++++ E LDP L+ +L K+ + G
Sbjct: 3481 SKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTF 3540
Query: 3467 LMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKE 3526
+++GDKE + F+ YITTKL NP ++PE +AKT++++F V +GLE QLL V+ E
Sbjct: 3541 KVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTE 3600
Query: 3527 RPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEV 3586
+ ELE ++ L+ ++ KRK+KELED +L L+ GSL+DD L+ L T+K TA EV
Sbjct: 3601 KQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEV 3660
Query: 3587 TEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSI 3646
+E+L + TEI + A+E +RP A R SIL+F++ +M ++ MYQ SL ++ LF S+
Sbjct: 3661 SEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSM 3720
Query: 3647 DKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEY 3706
+S +S + RI + +Y TY V+ Y+ R L+E HK LF M KI G + E+
Sbjct: 3721 ARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREF 3780
Query: 3707 NFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYT 3766
++GG LD + P W+ D W N+ EL KL F +MN + + W W+
Sbjct: 3781 QALIKGGAALDLKACPPKP-YRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFD 3839
Query: 3767 NAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKS 3826
APE+ ++P + ++ + ++L++RS DR F +I +L ++ EP +LN++
Sbjct: 3840 KDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEK 3899
Query: 3827 VLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVT 3886
E+S R+PL+ LS G DPT+ + LA+ + + R +S+GQGQ A +L++ +
Sbjct: 3900 TWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHARKLIQMSMQ 3957
Query: 3887 QGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMT 3946
QG WV L NCHL L +M L L + E SFR+W+++ PH FPI++LQ S+K T
Sbjct: 3958 QGGWVLLQNCHLGLEFMEEL--LETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFT 4015
Query: 3947 TEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNII 4006
EPP+G++A + R + +++ + P +K +L+++ F HS + ER+KF LGWNI
Sbjct: 4016 NEPPQGVRAGLKRTFAGINQDLLDISNLP-MWKPMLYTVAFLHSTVQERRKFGPLGWNIP 4074
Query: 4007 YGFNDSDFEVSENLLSLYLDEYE---ETPWDALKYLIAGINYGGHVTDDWDRRLLTTYIN 4063
Y FN +DF S + +LDE + W+ ++Y+I + YGG VTDD+D+RLL +
Sbjct: 4075 YEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFAR 4134
Query: 4064 DYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQI 4123
+F ++ F + Y IP +L Y EYI LP +D PE FG HPNAD+ Q
Sbjct: 4135 VWFSEKMFEPSFCFYTG---YKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQS 4191
Query: 4124 TEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAADVKQKI-PEMIDYEGTQKLLALDP 4182
A + +T+ ++QP+ + G+TRE V L+ D+ K+ P+ I +E +L+ +
Sbjct: 4192 NTASAVLETITNIQPKESGGGV-GETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGH 4250
Query: 4183 -SPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWG 4241
+ +N+ L QEI R ++ + SL+DL+ I+G I+MS +L + + ++DA +P LW
Sbjct: 4251 LNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWK 4310
Query: 4242 KAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSAR-QN 4300
+ L W +L R QF W RP V FW++GF P GFLTA+ Q R
Sbjct: 4311 RVSWDSSTLGFWFTELLERNAQFSTWIFEGRPNV-FWMTGFFNPQGFLTAMRQEVTRAHK 4369
Query: 4301 NVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLM 4360
++D+++ V + PP +GV++ GLY++GA WDR+N L+E+ P L +
Sbjct: 4370 GWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQL 4429
Query: 4361 PTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTA 4420
P +H S +Y CP Y P R +F+ + LR+ ++PDHWI RG A
Sbjct: 4430 PVLHIFAINSTAPKDPKLYVCPIYKKPRRTD----LTFITVVYLRT-VLSPDHWILRGVA 4484
Query: 4421 LLMSL 4425
LL +
Sbjct: 4485 LLCDI 4489
Score = 88.6 bits (218), Expect = 1e-16
Identities = 67/235 (28%), Positives = 117/235 (49%), Gaps = 19/235 (8%)
Query: 174 LLGGVFAPQIFANTGWP--------ESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPA 225
+L +F P + A W ES ++ F ++++L+ L R +EG TV
Sbjct: 57 MLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINRYLSFLDGARISIEG-TVKLKTI 115
Query: 226 EAMNMKPEMVIKD-------KELVQRLETSMIHWTRQIKEML--SAQETVETGENLGPLE 276
+ +N ++ E V +LE ++ W +QI+++L S Q E G++ GPL
Sbjct: 116 DNVNFSKLHTFEEVTAAASNSETVHQLEEVLMVWYKQIEQVLIESEQMRKEAGDS-GPLT 174
Query: 277 EIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNL 336
E+E W+ + I +Q+ K V ++L++A S L + L +I D + +++ N+
Sbjct: 175 ELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNV 234
Query: 337 TFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKV 391
+L L++ Q L ++ + LI+ IR+I S +YNT ER+TSLF KV
Sbjct: 235 RYLYTLEKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKV 289
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1427 bits (3693), Expect = 0.0
Identities = 1065/4006 (26%), Positives = 1906/4006 (47%), Gaps = 309/4006 (7%)
Query: 629 LDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILRENLLLVARDYNRIIAM 688
L VNF ++ L E+ + L F P +VN A +A L +L+ R Y R
Sbjct: 735 LKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTC-- 792
Query: 689 LSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHASKVQMIVNEFKAST 748
E+ + I LL GLKK AL + E + K+ V +
Sbjct: 793 ----EKVEERNTISLLVA----GLKKEVQALIAEGIALVWE----SYKLDPYVQRLAETV 840
Query: 749 LTIGWRAQEM---SEK--LLVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLHQ-DVVTI 802
+ ++ EK L VR +Y F E + AV +NLH + I
Sbjct: 841 FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDD--LNLHSYSNLPI 898
Query: 803 MTNSY--EVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPN 860
N E+ + G +Q + L ED +++ ++S G+ K
Sbjct: 899 WVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKN- 957
Query: 861 PLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTKRK-- 918
+ ++L+ + + +P ++ + +F+ V LP I ++R
Sbjct: 958 --------VVHELRITNQVIYLNPPIEECR---YKLYQEMFAWKMVVLSLPRIQSQRYQV 1006
Query: 919 -LHREPIQTVVEQDEDIKKIQTQISSG----------MTNNASLLQNYLKTWDMYREIWE 967
+H E + E+++ + T++ G + S ++ Y+K W Y+ +W+
Sbjct: 1007 GVHYE----LTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWD 1062
Query: 968 INKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQH 1027
+ ++ Y RL ++ + A + + + ET V++D ++ +
Sbjct: 1063 MQAENI---YNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLK 1119
Query: 1028 CNEWQNKFATLLREMAAGRLLELHTYLKENAEKISR---PPQTLEELGVSLQLVDALKHD 1084
+ W + + +M + E H+ + ++ +++ + + + + V +LK
Sbjct: 1120 YDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRK 1179
Query: 1085 LANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEK 1144
+ E Q+ +LEK S L +D++ GEW F + +++
Sbjct: 1180 IKQFEKQVELYRNGQRLLEKQRFQFPPSWL-YIDNIEGEWGAFNDIMRRKDSAIQQQVAN 1238
Query: 1145 FKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLR 1204
+ ++ + + LL D+E T N+ AL +T ++++
Sbjct: 1239 LQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCA 1298
Query: 1205 ANLGIFKIEQP-----PSKDLQNLEKELDALQQIW-EIARDWEENWNEWKTGRFLILQTE 1258
++ + +Q +EL L+ +W E+++ WE+ ++ K ++ +Q
Sbjct: 1299 KAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQI-DQMKEQPWVSVQPR 1357
Query: 1259 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ 1318
+ L +L R + E + ++ + + L+ +L++ AL++RHW Q
Sbjct: 1358 KLRQNLDALLNQLKSFPARL--RQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQ 1415
Query: 1319 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT 1378
+ + + TL QI ++ + ++ + ++ A E+A+E L+ I + W+
Sbjct: 1416 LMKRLHVNW--VVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTY 1473
Query: 1379 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE 1438
+LD+V Y++K +RG +++F ++++ ++S MK S + K FE+D WE L+ I+
Sbjct: 1474 ELDLVNYQNKCR-LIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMA 1532
Query: 1439 VIEMILTVQRQWMYLENIFLGE-DIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRST 1497
+ ++ + VQR+W+YLE IF G DI+ LP E+ F +++ + A+M +++K +
Sbjct: 1533 LFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVL 1592
Query: 1498 HHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQP 1557
+ G+ +L + +L IQK+L YLE +R FPRFYF+ ++DLLEI+G S+N +Q
Sbjct: 1593 NIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQK 1652
Query: 1558 HLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFL-EGP-VESWLGDVEQ 1615
H KK F + + + + +G+ S +GE + F V + E P + WL VE+
Sbjct: 1653 HFKKMFAGVSSIILNEDNSV-----VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEK 1707
Query: 1616 TMRVTLRDLLRNCHLALRKF-------LNKRDKWVKEWAGQVVITASQIQWTADVTKCLL 1668
MRVTL LL + F N W+ ++ Q+V+ ++QI W+ +V L
Sbjct: 1708 EMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALS 1767
Query: 1669 TAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYK 1728
+ D L + N LN ++++ + R K+ L+T +H RDV L K
Sbjct: 1768 SMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIK 1827
Query: 1729 SGLMDVNSFDWLSQLRFYWEKDLDDCV----IRQTNTQFQYNYEYLGNSGRLVITPLTDR 1784
S + + SF+WLSQ+RFY++ D + I+ N +F Y +EYLG +LV TPLTDR
Sbjct: 1828 SKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDR 1887
Query: 1785 CYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSG 1844
CY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC E D+++MGR++ G
Sbjct: 1888 CYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVG 1947
Query: 1845 LAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFD-----------GFEI 1893
L Q GAWGCFDEFNR+ +LS V+ Q+ CI AL ++ ++D ++
Sbjct: 1948 LCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREH-SNPNYDKTSAPITCELLNKQV 2006
Query: 1894 NLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILA 1953
+ IFITMNPGYAGR+ LP+NLK +FR +AM PD LIA+++L+ +GF ++LA
Sbjct: 2007 KVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLA 2066
Query: 1954 KKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAG--KKRRLQP---------------- 1995
K+ + L +QLS Q HYDFGLRAL S+L AG K+ R+Q
Sbjct: 2067 NKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGE 2126
Query: 1996 ---DLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEI 2052
+L ++E+L+ S+ + + KL + D PL +++ D+FP ++ + LRE +++
Sbjct: 2127 IAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVC 2186
Query: 2053 RDM------GLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCR 2106
++M G + + KV QLY+ H M+VG +GSGK+ +WR+L +L L
Sbjct: 2187 QEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERL-- 2244
Query: 2107 AGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRT---ACADEKPDEKW 2163
G + ++PKA+S LYG D +T EWTDG+ + V+R + E +W
Sbjct: 2245 EGVEGVAHI----IDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQW 2300
Query: 2164 ILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCG 2223
I+FDG VD W+EN+NSV+DDNK+LTL NGER+++P V ++FEV+DL A+ ATVSRCG
Sbjct: 2301 IVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCG 2360
Query: 2224 MVYTDYADLGWKPYVQSWLEKR-----PKAEVEPLQRMF------EKLINKMLAFKKDNC 2272
MV+ L ++L + + E E +R E+ + ML ++D
Sbjct: 2361 MVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAA 2420
Query: 2273 KELVPLPEYSGITS--------------------LCKLYSALATPENGVN---------P 2303
+ P +G+ + L L+S L V P
Sbjct: 2421 TIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFP 2480
Query: 2304 ADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEG----SFPNKDTV-YEYF 2358
E ++ V++++WS+ + R + Y+R I + PN + YE
Sbjct: 2481 MQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVS 2540
Query: 2359 VDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPV 2418
+ + W+ ++ K+P+ ++VPT+DTVR+ L+ + +A P++L GP
Sbjct: 2541 ISGE---WSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPP 2597
Query: 2419 GTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVE-KRTKG--VYVPFG- 2474
G+GKT S L++LP + V+ +N S+ TT + + E +RT V P
Sbjct: 2598 GSGKTMTLFSALRALPDME--VVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQL 2655
Query: 2475 GKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT-IKYIREMFLMAAMGP 2533
GK ++ F D++N+P D +G+Q + IR +++G +Y + QT +K R F+ A P
Sbjct: 2656 GKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPP 2715
Query: 2534 PGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATL 2593
GR +S R ++ + +P + + +I+GT N+ + ++ +T A +
Sbjct: 2716 TDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTF-NRAMLRLIPSLRTYAEPLTAAMV 2774
Query: 2594 DMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTK-SSITRLWIHECFRVF 2652
+ Y +RF T+ HY+++ R++++ +G+ A + + R+W HE R+F
Sbjct: 2775 EFYTMSQERFTQD-TQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLF 2833
Query: 2653 SDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVL 2712
DRLV+ + I F S RP ++ ++L + + D +L
Sbjct: 2834 QDRLVEDEERRWTDENIDTVALKHFPNIDREKAMS-RPILYSNWLSKDYIPVDQEEL--- 2889
Query: 2713 KTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLA 2772
+ ++ L + VP LVLF E ++H+ RI R+ QP+G++LL+G+ G+G+ +L+
Sbjct: 2890 RDYVKARLKVFYEEELDVP--LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLS 2947
Query: 2773 RLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLED 2832
R + + + +QI+V + Y ++F +D++ + R++G + + +FI ++ + D FLE
Sbjct: 2948 RFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLER 3007
Query: 2833 INNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVP-ESSDSLFAYLIERVQNNLHIVLC 2891
+N +L++GEVP L++ DE+ + + + A+ E + +S + L+ + +V NLH+V
Sbjct: 3008 MNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFT 3067
Query: 2892 LSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI------ 2945
++P + ++ PAL N +NWF +W EAL +V ++ +DL I
Sbjct: 3068 MNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMP 3127
Query: 2946 -----------HRK-VAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLL 2993
HR+ + V +H ++ Q + ++ R +TP YL+ ++ Y L
Sbjct: 3128 VVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLF 3187
Query: 2994 GEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQK 3053
EKR EL Q L GL KI ET ++V+ + +L +++ + L +V+ +
Sbjct: 3188 HEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQ 3247
Query: 3054 READEQQKAVTANSEKIAVEEIKCQALAD---NAQKDLEEALPALEEAMRALESLNKKDI 3110
+EA++++ E++ ++ + +AD + ++DL++ PA+ EA A++S+ K+ +
Sbjct: 3248 QEAEKKKVMSQEIQEQLHKQQ---EVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHL 3304
Query: 3111 GEIKSYGRPPAQVEIVMQAVMILRGNEPT-WAEAKRQLGEQNFIKSLINFDKDNISDKVL 3169
E++S PPA V++ ++++ +L G T W + + + +NFI +++NF + ISD +
Sbjct: 3305 VEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIR 3364
Query: 3170 KKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLR 3228
+K+ Y + P + +I+ R SLA + W A Y + + VEP R + +
Sbjct: 3365 EKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAK 3424
Query: 3229 EKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAG 3288
+ Q E ++ +R++ + K++Y +++ + ++ +E K+ R+ L+ L+
Sbjct: 3425 DNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSA 3484
Query: 3289 EKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPC 3348
E+ RWE+T + + + + GDCLL+AAF++Y G F R + W + + +
Sbjct: 3485 ERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTT-WSHHLQQANIQF 3543
Query: 3349 SPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNM 3408
A +L N + W LP+D TEN I++ R NR+ L+IDP QA ++I N
Sbjct: 3544 RTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNE 3603
Query: 3409 EGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLM 3468
+ + + + LE A+ FG P+L+Q+V+ Y DP LNP+LN+ V R GGR+L+
Sbjct: 3604 YKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESY-DPVLNPVLNREVRRTGGRVLI 3662
Query: 3469 RIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERP 3528
+GD++++ + +F +++T+ + P+ ++ T VNF V L++Q L V++ ERP
Sbjct: 3663 TLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERP 3722
Query: 3529 ELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTE 3588
+++E++ L+ + +L++LE +L+ LNE G +LDD ++ TL K A EVT
Sbjct: 3723 DVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTR 3782
Query: 3589 QLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDK 3648
++E ++ + + Y P + S ++F + + I +YQ+SL ++ ++ + +
Sbjct: 3783 KVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYE 3842
Query: 3649 SHRSNKLEDRIDYLN----DYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMD 3704
+ + D L+ D A R L + H K+ T G+ D
Sbjct: 3843 NPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYD 3902
Query: 3705 -EYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHL 3763
E+ FLRG ++ G P L + + L L F L+ Q + +
Sbjct: 3903 AEFQHFLRGNEIVLSAG--STPRIQGLTVEQAEAVVRLSCLPAFKDLIAKV-QADEQFGI 3959
Query: 3764 WYTNAAPEKAMLPGEWENAC------NEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRF- 3816
W +++PE+ +P W + R+L++++ R DR+ F+ TNLG F
Sbjct: 3960 WLDSSSPEQT-VPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFM 4018
Query: 3817 --IEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQA 3874
+E P+ V + P +P++ PG D + + LA A+ +G
Sbjct: 4019 SIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFN 4078
Query: 3875 PIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDF 3934
A + + V G WV L N HL+ W+ L+K + LQ PH FRL+L+ +P
Sbjct: 4079 Q-ADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQ---PHACFRLFLTMEINPKV 4134
Query: 3935 PISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLE 3994
P+++L+ EPP G+KANM R + S P C P + +L F L +FH+++ E
Sbjct: 4135 PVNLLRAGRIFVFEPPPGVKANMLRTFS--SIPVSRICKSPNERARLYFLLAWFHAIIQE 4192
Query: 3995 RKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEY---------EETPWDALKYLIAGINY 4045
R ++ LGW+ Y F +SD + + + +LD+ ++ PW ALK L+A Y
Sbjct: 4193 RLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIY 4252
Query: 4046 GGHVTDDWDRRLLTTYINDYFCDQSLSTPFH---RLSALETYFIPKDGSLASYKEYISLL 4102
GG V +++D+RLL T++ F +S + F ++ + +P + +++ LL
Sbjct: 4253 GGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELL 4312
Query: 4103 PGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQ-----PQITPTRAGGQTREEKVLE- 4156
P P G NA+ T+ + +L +Q + +TR + +
Sbjct: 4313 PDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDG 4372
Query: 4157 ----------LAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFS 4206
A++ IP+ + + ++ + PL +E++ L+Q +
Sbjct: 4373 RPAWMRTLHTTASNWLHLIPQTLSH--LKRTVENIKDPLFRFFEREVKMGAKLLQDVRQD 4430
Query: 4207 LTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGK-AYPSQKPLAAWTRDLAMRVEQFE 4265
L D+ + +G + L + N + +P W P+ + W D + R++Q +
Sbjct: 4431 LADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQ 4490
Query: 4266 -------LWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD 4318
++ + L G P ++TA Q A+ N+ S++ L E V+T
Sbjct: 4491 NISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQG 4550
Query: 4319 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAK-G 4377
+ L V GL L+GA + L A + +P R + K
Sbjct: 4551 ATL---DACSFGVTGLKLQGATCNNNKLSLSNA----ISTALPLTQLRWVKQTNTEKKAS 4603
Query: 4378 MYSCPCYYYPNRAGSSDRASFVIGIDLRSGAM-TPDHWIKRGTALL 4422
+ + P Y + RA + +D P + +RG A+L
Sbjct: 4604 VVTLPVYL------NFTRADLIFTVDFEIATKEDPRSFYERGVAVL 4643
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1357 bits (3511), Expect = 0.0
Identities = 985/3539 (27%), Positives = 1726/3539 (48%), Gaps = 239/3539 (6%)
Query: 1001 VQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEK 1060
V++ + + + ++C+ +K + + + L++ L E+ T++ E E
Sbjct: 896 VERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEV 955
Query: 1061 ISRPPQTLEELG-VSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDS 1119
++ PQ++EE+G +LQ L + +I P+ ++ + V LE + +
Sbjct: 956 LTIMPQSVEEIGDANLQY-----SKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISN 1010
Query: 1120 LNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFK------GHF 1173
L +W F+ + + M+K E K + + ++ LE F+ + G
Sbjct: 1011 LKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQE----LEKFKARWDQLKPGDD 1066
Query: 1174 TSNVGYMSALDQ----ITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDA 1229
G + LD+ I + + + L + F++E+P ++ K++++
Sbjct: 1067 VIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIES 1126
Query: 1230 LQQIWEIARDWEENWNEWKTGRFLILQTET--METTAHGLFRRLTKLAKEYKDRNWEIIE 1287
QIW ++++ + E ++ +T+T E RL K+ + + +
Sbjct: 1127 CAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKV-----EEHSVMTV 1181
Query: 1288 TTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQH 1347
+S+++++K +P++ +R L HW + + E ++ + D
Sbjct: 1182 KLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVA-DTI 1240
Query: 1348 VEK---IGEISASATKELAIEVALQNIAKTWDV----TQLDIVPYKDKGHHRLRGTEEVF 1400
V K + ++++ A E+ I AL+ + W V T +D + + ++ +++
Sbjct: 1241 VAKAADLKDLNSRAQGEVTIREALREL-DLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIV 1299
Query: 1401 QALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGE 1460
+ DN+ L ++K S + K FE V WER L+ + E ++ + +QR+W+YLE IF
Sbjct: 1300 NQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-- 1357
Query: 1461 DIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSL 1520
R LP E T F++V+ ++++IM + KDN T H G+ ++L+ + L+ QKSL
Sbjct: 1358 --RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSL 1415
Query: 1521 DMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSK 1580
+ +LE KR FPRFYF+ +DDLLEILGQS NP +Q HLKK F I + + SK
Sbjct: 1416 NEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDE----KSK 1471
Query: 1581 WEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRD 1640
M S +GE + F + V L VE+WL D+ M+ TL LL+ C R D
Sbjct: 1472 -HITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVD 1530
Query: 1641 KWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGN 1700
+ + Q++ A QI++T DV + + L V K Q + ++ SE
Sbjct: 1531 PSL--FPSQILCLAEQIKFTEDVENAIKDHSLHQIETQL-VNKLEQYTNIDTSSEDPGNT 1587
Query: 1701 LTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTN 1760
+ I+ LK+ AL+ IH DV+++L + + + W QLRFY + D C ++ +
Sbjct: 1588 ESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD-HTCCVQMVD 1646
Query: 1761 TQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKAL 1820
++FQY YEY GN+ +LV TPLTD+CY+TLT A+ + GG+P GPAGTGKTE+VK LG L
Sbjct: 1647 SEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLL 1706
Query: 1821 GIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALA 1880
G V+V NC EG+D KSMGR++ GL + GAWGCFDEFNR+ VLS V+ QI I AL
Sbjct: 1707 GRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALK 1766
Query: 1881 AGLTHFHFDGFEINLVWSCGIFITMNP---GYAGRTELPENLKSMFRPIAMVVPDSTLIA 1937
T G E+ + + GIFITMNP GY GR +LP+NLK +FRP+AM PD+ LIA
Sbjct: 1767 NHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIA 1826
Query: 1938 EIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGK------KR 1991
E+IL+ EGF + K+L++K+ +++L+ + L+ Q HYD+GLRAL ++LR +G K
Sbjct: 1827 EVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKS 1886
Query: 1992 RLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQE 2051
+ + +++ ++R ++K T D F+A+++D+FP IEL ++Y +L ++Q
Sbjct: 1887 GTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQV 1946
Query: 2052 IRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPN 2111
+ + P + K +LYE R +IVG +G+GK+ WR+L+A+L C+ G
Sbjct: 1947 FEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAAL---CKTG--- 2000
Query: 2112 FNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVD 2171
+V+++ +NPKA+ +L G D+ T EW+DG+L++ R + + WI+ DG +D
Sbjct: 2001 -KVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDID 2059
Query: 2172 TLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYAD 2231
WIE++NSV+DDN++LT+ +GERI V+ +FE DL+ ASPAT+SR GM++ +
Sbjct: 2060 PEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEE 2119
Query: 2232 LGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLY 2291
++SWL +P L+ K L + ++ +Y TSL
Sbjct: 2120 TDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQW-------VLKQNDYVVETSL---- 2168
Query: 2292 SALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGR----KRIDSYLREIEGS 2347
+ T NG++ G F+ ++I + +++ + R K + + RE
Sbjct: 2169 --VGTVMNGLSHLHG----CRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPD 2222
Query: 2348 FPNKDTVYEYFVDPKIRSWT--SFEDKLPKSWRYPPNAPFYKIMVPTVDTVR-YNYLVSS 2404
F Y ++ ++ ED + P ++ T D R +Y
Sbjct: 2223 FHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLP----VIQTPDMQRGLDYFKPW 2278
Query: 2405 LVAN-QNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESR-- 2461
L ++ + P +LVGP G GK + + L S+Q + V+ SAQTTS ++ +
Sbjct: 2279 LSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQ--IATVHCSAQTTSRHLLQKLSQTCM 2336
Query: 2462 -VEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK 2520
+ T VY P + ++ ++ D+N+P D +G+ + ++ + Y +YD + +
Sbjct: 2337 VISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVG 2396
Query: 2521 YIREMFLMAAMGPPGG-GRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEE 2579
+ + ++A+M G GR ++ R S + ++ +P + Q+ I+G + L +
Sbjct: 2397 -LENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLK 2455
Query: 2580 EVKPIGN-----VVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFH 2634
G+ ++ + + +Y V +F HY F +++ G+ R + +
Sbjct: 2456 NHSIWGSSSKIYLLAGSMVQVYEQVRAKFT-VDDYSHYFFTPCILTQWVLGLFRYDLEGG 2514
Query: 2635 DTKSS---ITRLWIHECFRVFSDRLVDAAD--------TEAFMGI----ISDKLGSFFDL 2679
+ + + +E R+F D++V A + T F G I D + F +
Sbjct: 2515 SSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYV 2574
Query: 2680 TF--HHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLF 2737
T+ H ++ P G L + T LK V++ L Y + ++LF
Sbjct: 2575 TWGARHNSGARAAP--GQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQ--NLDILLF 2630
Query: 2738 REAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEF 2797
E +E+++RI RV+ P G++LL G G GR+++ L S + F ++++ Y ++F
Sbjct: 2631 HEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQF 2690
Query: 2798 RDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSH 2857
++D+K + + AG+E + + D Q +FLE IN++LSSGEVP LY +E E +
Sbjct: 2691 KNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLP 2750
Query: 2858 IIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINW 2917
+ DQA + +F Y R+Q NLHIVL + F PAL + W
Sbjct: 2751 LKDQASQDGF---FGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLW 2807
Query: 2918 FSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQ------------IFVTMHWSVAQYSQ 2965
W ++ ++ E G + N ++ + F+ +H S Y
Sbjct: 2808 MEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYG- 2866
Query: 2966 KMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMS 3025
TP++Y+ L Y + K++ELL + + L+ G+ K++E + V ++
Sbjct: 2867 -----------ATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELN 2915
Query: 3026 LELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQ 3085
+ + + Q + + L +I ++A EQ+ + +IA E +K + +
Sbjct: 2916 RKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKID 2975
Query: 3086 KDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN-EPTWAEAK 3144
+L+E P + EA A+ ++ + + EI+S PP + +++ V+ L G + +W K
Sbjct: 2976 DELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMK 3035
Query: 3145 RQLGEQNFIKSLINFDKDNISDKVLKKIGA--YCAQPDFQPDIIGRVSLAAKSLCMWVRA 3202
L ++ + + FD NIS ++ + + + + F P R S AA L WV+A
Sbjct: 3036 SFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKA 3095
Query: 3203 MELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQK 3262
Y + + P + L++ + + +E L V +K+ LK+++ + ++
Sbjct: 3096 NIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEA 3155
Query: 3263 EELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMG 3322
+L + + + ++ A +L++ L E RW V + E+L L LAAAF++Y+
Sbjct: 3156 AKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLS 3215
Query: 3323 PFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENG 3382
+ R + + W F + FLC ++ W +GLPSD S EN
Sbjct: 3216 AAPESLRKTCLEE------WTKSAGLE-KFDLRRFLCTESEQLIWKSEGLPSDDLSIENA 3268
Query: 3383 IIVTRG---NRWA----LMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFG 3435
+++ + W+ +IDP +QA +W+K L++I+ Q S+++ LE A+ FG
Sbjct: 3269 LVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFG 3328
Query: 3436 YPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYS 3495
+++Q + + ++P L P+L + + G R +++IGDK ++YN FR +++T+ NP
Sbjct: 3329 KTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIP 3387
Query: 3496 PETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEI 3555
P+ ++ T VNF GL QLL + ++ E+P+LEEQK L+ K +L +LE+ +
Sbjct: 3388 PDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESL 3447
Query: 3556 LRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRAS 3615
L L + G++L++ L+ +L+ +K ++ + E L+ S +I+ D R+AY P A+ AS
Sbjct: 3448 LETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESAS 3507
Query: 3616 ILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTC 3675
++F+++D+ I+ MY+FSL A++ LF ++ S E RI L + VY Y C
Sbjct: 3508 KMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYIC 3567
Query: 3676 RTLFERHKLLFSFHMCAKI-LETSGKLNMDEYNFFLRGGVV--LDREGQMDNPCSSWL-A 3731
R LF+ +L+F+ H + E + D + + G ++ D + ++ + SW+
Sbjct: 3568 RCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQ 3627
Query: 3732 DAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLI 3791
+ W T L + + + FE W +Y N+ E+ P + Q++L+
Sbjct: 3628 ERSWAVATLKIALPSLYQTL-CFEDAAL-WRTYYNNSMCEQE-FPSILAKKVSLFQQILV 3684
Query: 3792 VRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSAL 3851
V++LR DR+ + F LG + + P LN+K + +++ P++ I+SPG DP+ L
Sbjct: 3685 VQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQEL 3744
Query: 3852 LQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVE 3911
+LA + +H +++GQGQA +A ++L+E G W+ L N HL +SW+P L+K +
Sbjct: 3745 QELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELN 3804
Query: 3912 QLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSR 3971
LQ P +FRLWL++ HP+F +LQ S+K+T E P GLK N+ R Y+ + Q S+
Sbjct: 3805 TLQ---PKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISK 3861
Query: 3972 CSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEET 4031
+ LFSL +FH+ ER+ ++ GW Y F+ SD N++ D ++
Sbjct: 3862 KDNTHR-AHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDV 3920
Query: 4032 PWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETY----FIP 4087
W+ + L+ YGG + + +D R+L +Y+ +F + S+ F++ + + +P
Sbjct: 3921 QWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFF-NSSVIDVFNQRNKKSIFPYSVSLP 3979
Query: 4088 KDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGG 4147
+ S+ Y+ I +P D P FG N +SQ + + L L IT AG
Sbjct: 3980 QSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSIT---AGS 4036
Query: 4148 QTREE--------------KVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEI 4193
+ E K+ + + + QK+P D +G SP+ ++ E
Sbjct: 4037 KFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQG---------SPILSFIILEQ 4087
Query: 4194 QRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAW 4253
L+Q++ SL L K I+G ++S+ ++++ + + + P W + + +
Sbjct: 4088 FNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPLQY 4147
Query: 4254 TRDLAMRVEQFELWASRARPPVIFW----LSGFTFPTGFLTAVLQSSARQNNVSVDSLSW 4309
R L R + W +A + LS P FL A+ Q +AR SVDSL
Sbjct: 4148 LRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSL-- 4205
Query: 4310 EFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWD----RKNSCLVEAEPMQLVCLMPTIHF 4365
+F+ S + K + + GL LEG +D +N + L C M I
Sbjct: 4206 KFVASW---KGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWI-- 4260
Query: 4366 RPAESRKKSAKGMYS-CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLM 4423
+ A G YS C P S++R V ID+ G D WI+ G AL +
Sbjct: 4261 ------PQDACGPYSPDECISLPVYT-SAERDRVVTNIDVPCGG-NQDQWIQCGAALFL 4311
Score = 32.7 bits (73), Expect = 8.2
Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 74 ADVKPLFLSRAALT--GLADAVWTQE---HDAILEHFAQDPTESILTIFIDPC---FGLK 125
ADV+ LF+ GL +W Q + + +F D + +L + F
Sbjct: 6 ADVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGISFSNT 65
Query: 126 LELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFA 185
+E G T+++++ F + P IT EN + ++ I +L + + VFAP +
Sbjct: 66 IEFG---DTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPMLLK 122
Query: 186 NTGW 189
+ W
Sbjct: 123 DQEW 126
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 1145 bits (2963), Expect = 0.0
Identities = 722/2022 (35%), Positives = 1079/2022 (53%), Gaps = 128/2022 (6%)
Query: 864 QVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTKRKLHREP 923
Q L I K +L ++EF PT Q L V + + + +P L+ P
Sbjct: 321 QRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTST---P 377
Query: 924 IQTVVEQDEDIKK--IQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQRLN 981
+ E E + + T ++ N ++Y + Y + + I +Q +
Sbjct: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETFQTED 437
Query: 982 PPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLRE 1041
+ I ++ +A+ + + V LDC LK L + N LL +
Sbjct: 438 HTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKTGLTNKAKAFAN---ILLND 494
Query: 1042 MAAGRLLELHTY------LKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPI 1095
+A+ E +KE+A K+ P+T EE+ + V+ K +E I I
Sbjct: 495 IASKYRKENECICSEFEAIKEHALKV---PETTEEMMDLISYVE--KARTVGIEELILRI 549
Query: 1096 HEQFA----ILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML---KKHKEKFKTG 1148
E L+ + P ED L + W + D L KHK++
Sbjct: 550 QESKRQMSYFLDVFLFPQEDLALNATVLM---WPRKINPIFDENDELIENAKHKKE---- 602
Query: 1149 LIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQ----ITQVRAMLMAMREEENSLR 1204
++ K L+ + E + + L++ +T VR + ++E E +++
Sbjct: 603 -----NELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESEEAVQ 657
Query: 1205 ---ANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETME 1261
+FK E +L L+ ++ Q+ + W+ + W G FL L E+ME
Sbjct: 658 FINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESME 717
Query: 1262 TTAHGLFRRL--------TKLAKEYKDRNWEIIETT--RSKIEQFKRTMPLISDLRNPAL 1311
R + TKL KE +++ + + KIE+ + I+ R +
Sbjct: 718 ADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCR---M 774
Query: 1312 RERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNI 1371
R RHW Q+ + + + +S + TL ++++L + ++E+ ISA A+KE ++E A+ +
Sbjct: 775 RARHWKQISEIVGYDLTPDSGT-TLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTM 833
Query: 1372 AKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWER 1431
TW+ I Y+D G L +E+ L+D + TM+ S F+K FE ++ WE
Sbjct: 834 IGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWED 893
Query: 1432 CLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDN 1491
L I E I+ L VQ QW+YLE IF EDI +Q+P E F V+ +W+ IM KD
Sbjct: 894 RLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDP 953
Query: 1492 NALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRN 1551
L +T GLL+ L N +LE I K L+ YLE KR FPRF+FLSND++LEIL ++++
Sbjct: 954 KVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKD 1013
Query: 1552 PEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLE---GPVES 1608
P VQPHLKKCF+ I L + M+S +GE ++ + + G VE
Sbjct: 1014 PLRVQPHLKKCFEGIAKLEFLP------NLDIKAMYSSEGERVELIALISTSAARGAVEK 1067
Query: 1609 WLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLL 1668
WL VE M ++ D++ LA + + R WV+EW GQVV+ SQ+ WT++ + +
Sbjct: 1068 WLIQVEDLMLRSVHDVIAAARLAYPE--SARRDWVREWPGQVVLCISQMFWTSETQEVIS 1125
Query: 1669 TAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYK 1728
E LK K + LN+ E +RG L+K R + ALVTI++HARDV+ + K
Sbjct: 1126 GGTEG-----LKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIK 1180
Query: 1729 SGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMT 1788
G+ F WL+QLR+YWE + + +R N +Y YEYLGNS RLVITPLTDRCY T
Sbjct: 1181 MGVSHDTDFLWLAQLRYYWENE--NARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRT 1238
Query: 1789 LTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQT 1848
L A +L+ GG+P+GPAGTGKTET KDL KAL + +V NCS+GLDY +MG+ + GLA +
Sbjct: 1239 LIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASS 1298
Query: 1849 GAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPG 1908
GAW CFDEFNRI +EVLSVVA QILCI A+ L F F+G E+ L +C + ITMNPG
Sbjct: 1299 GAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPG 1358
Query: 1909 YAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLS 1968
YAGR+ELP+NLK +FR +AM+VP+ LIAEI L+ GF N + L+ K+ Y L +QLS
Sbjct: 1359 YAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLS 1418
Query: 1969 RQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQ 2028
Q HYD+G+RA+ ++L AG + P+ ++ +LL S++D+N K S D PLFN I
Sbjct: 1419 SQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITS 1478
Query: 2029 DLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGS 2088
DLFP I+LP DY + E + LQ F L K+ Q YE RH M+VG +
Sbjct: 1479 DLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFA 1538
Query: 2089 GKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSS 2148
KT +L +L+ + G V +NPK++++G+L+G++D ++EWTDGI+++
Sbjct: 1539 AKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVAN 1598
Query: 2149 VMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEV 2208
R E PD KW++FDGP+DTLWIE+MN+V+DDNK L L++GE I M Q+SL+FE
Sbjct: 1599 TFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFET 1658
Query: 2209 EDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLE--KRPKAEVEPLQRMFEKLINKMLA 2266
DL+ ASPATVSRCGM+Y + + LGW+P V SWL K P E E Q + L ++
Sbjct: 1659 MDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPE-YQALLRGLFAWLIP 1717
Query: 2267 FKKDNCKELVPLPEYSGITSLCKLYSALAT--PENGVNPADGENYVTMV------EMTFV 2318
+ EL L Y T + K+ L T N + T + + F+
Sbjct: 1718 PSLNQRVELFQL-NYLYTTIVSKILKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFI 1776
Query: 2319 FSMIWSVCASVDEEGRKRIDSYLREI-----------------EGSFPNKDTVYEYFVDP 2361
FS+IWS+ S D +GR+ D+++R I E F K VY+Y +
Sbjct: 1777 FSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKGLVYDYMYEL 1836
Query: 2362 KIRS-WTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGT 2420
K + W + + + + I+VPT+DT+RY +L+ + P+L VGP GT
Sbjct: 1837 KNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPTGT 1896
Query: 2421 GKT-SIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMI 2479
GK+ + ++ L Q+ +N+SA+T++N VQ+II +R++KR KGV+ P GK I
Sbjct: 1897 GKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCI 1956
Query: 2480 TFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRT 2539
F+DD+NMPA + +G+QPP+EL+R + D G WYD + + ++ L+AAMGPPGGGR
Sbjct: 1957 IFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITLVDIELIAAMGPPGGGRN 2016
Query: 2540 VISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQ--DFEEEVKPIGNVVTEATLDMYN 2597
++PR FNI ++ + ++RIF +++ L+ +F E IGN + T+++Y
Sbjct: 2017 PVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTMEIYK 2076
Query: 2598 TVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLV 2657
V+ LPTPTK HY FNLRD S+V +G L +D K ++ RL++HE RVF DRL+
Sbjct: 2077 QSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFVHEVLRVFYDRLI 2136
Query: 2658 DAADT----EAFMGIISDKLGSFFDLTFHHLCPSKRPP--------IFGDFLK-----EP 2700
+ D + +I D F F HL P +FGD++ +
Sbjct: 2137 NDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLEGDD 2196
Query: 2701 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL 2760
+VY ++ ++ V++ L+EYN + M LV+FR +EH++RI RV+ Q GN LL
Sbjct: 2197 RVYIEIPNIHHFSDVVDQCLDEYNQTHK-TRMNLVIFRYVLEHLSRICRVLKQSGGNALL 2255
Query: 2761 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIK 2802
VG+GGSGRQSL RLA+S+ FQ E++K Y E+R+D+K
Sbjct: 2256 VGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMK 2297
Score = 597 bits (1538), Expect = e-169
Identities = 319/803 (39%), Positives = 471/803 (58%), Gaps = 18/803 (2%)
Query: 3635 LDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKI 3694
+ ++I++ + + ++S LE R+ YLND+ TY +Y CR+LFE+ KLLFSF +CA +
Sbjct: 2296 MKSFIAVPVTNRIVDNKSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANL 2355
Query: 3695 LETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSF 3754
L ++ E F L GGV L + NP +WL D W+ I + F GL F
Sbjct: 2356 LLARKEIEYQELMFLLTGGVSL--KSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHF 2413
Query: 3755 EQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGS 3814
++ +W Y + P A P + NE+Q+++I+R LR D++ +T+++ LG
Sbjct: 2414 CEHIYEWREIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGK 2473
Query: 3815 RFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMA-QRFHALSLGQGQ 3873
+F+EPP ++ DS PL+F+LSPG DP ++LL+ A M+ +F A+SLGQGQ
Sbjct: 2474 KFVEPPPFDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQ 2533
Query: 3874 APIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD 3933
PIAA++++ + +G WV L NCHL++SWMP L+K+ E E + SFRLWL+S P
Sbjct: 2534 GPIAAKMIKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK 2593
Query: 3934 FPISILQVSIKMTTEPPKGLKANMTRLYQL--MSEPQFSR-C-SKPAKYKKLLFSLCFFH 3989
FP++ILQ +KMT EPP GL+ N+ + Y +S+P+F + C K ++KLLF +CFFH
Sbjct: 2594 FPVTILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFH 2653
Query: 3990 SVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHV 4049
+++ ERKKF LGWNI YGFN+SD +S L L+++EY+ P++A+ YL NYGG V
Sbjct: 2654 ALVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRV 2713
Query: 4050 TDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPE 4109
TDDWDRRLL T + D++ + P ++ S YF P G+ Y E+I LP PE
Sbjct: 2714 TDDWDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPE 2773
Query: 4110 AFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAADVKQKIPEMI 4169
FG H N D++ + + +TLF++LL Q T A G T ++ +LE+ D+ K+P
Sbjct: 2774 IFGLHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGST-DQILLEITKDILNKLPSDF 2832
Query: 4170 DYE-GTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIF 4228
D E +K +N VL+QE++R+N L+ TI +L DLEK I+G++VM ++LE +
Sbjct: 2833 DIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALS 2892
Query: 4229 NCIFDAHVPPLWGK-AYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTG 4287
+ VP +W K +YPS KPL ++ D R+ + W + + P +FWLSGF F
Sbjct: 2893 GSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGK-PCVFWLSGFFFTQA 2951
Query: 4288 FLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSC 4347
FLT +Q+ AR+ +D L +EF V D S+ P+DGV++ GLYL+GA WDR++
Sbjct: 2952 FLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDT--SPEDGVYIHGLYLDGARWDRESGL 3009
Query: 4348 LVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSDRASFVIGID 4403
L E P L LMP I +P + + Y CP Y R G + +FVI +
Sbjct: 3010 LAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAML 3069
Query: 4404 LRSGAMTPDHWIKRGTALLMSLD 4426
L++ T HWIKRG ALL LD
Sbjct: 3070 LKTDQPT-RHWIKRGVALLCQLD 3091
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 893 bits (2307), Expect = 0.0
Identities = 587/1869 (31%), Positives = 935/1869 (50%), Gaps = 207/1869 (11%)
Query: 2749 RVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQA 2808
R++ + N +GI G G+++ A LA + D +++ ++ EF++ K+++ A
Sbjct: 2653 RLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHA 2712
Query: 2809 GVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVP 2868
G++ K T + + I +SFLED+N I+SSG +P+L++ E + I I
Sbjct: 2713 GLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHM 2772
Query: 2869 ESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLE 2928
++ SL ++ +R+ NLHI + +SP G FR R YP++++ TI+W+ WP+EALL
Sbjct: 2773 DNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLI 2832
Query: 2929 VAEKCLIG-VDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLS 2987
VA L V+ +EN+ K+A V +H S+ ++K E R Y TP YL+ +
Sbjct: 2833 VANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQFME 2892
Query: 2988 GYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLV 3047
+ +L + +E+ + ++ GL I E V M EL +V + K+ E +
Sbjct: 2893 TFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETLME 2952
Query: 3048 IIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNK 3107
+ + + ++ Q V + E +A E + A +L+ LPA ++A+ AL +L+K
Sbjct: 2953 KLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNALDK 3012
Query: 3108 KDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDK 3167
D+ E++ Y RPP V VM AV IL +P WA AK L E F+K LIN DKD+I DK
Sbjct: 3013 ADVAELRVYTRPPFLVLTVMNAVCILLQKKPNWATAKLLLSETGFLKKLINLDKDSIPDK 3072
Query: 3168 VLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQL 3227
V K+ PDF P I VS+A SLC WV A+ Y + +VV PK+I++ A L
Sbjct: 3073 VFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQVAEAQNVL 3132
Query: 3228 REKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLA 3287
+ + LAE Q L+ V E L L+ Y + +A+K+ L + + + A +L++ L
Sbjct: 3133 KIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCASVLLTVLE 3192
Query: 3288 GEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVP 3347
EK RW+ET+ ++ L ++GD LL+AA + Y G +R IVN+ W E +
Sbjct: 3193 DEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVNK-WETFCIENGIS 3251
Query: 3348 CSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKN 3407
S F++ + ++ W+ QGLP +S EN I++ G +W L+IDP QA KWI+
Sbjct: 3252 LSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPLLIDPHRQAHKWIRQ 3311
Query: 3408 MEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLL 3467
MEG + L+ + ++ S+Y + +E+A+ G VLLQN+ E L P L +L K + + G
Sbjct: 3312 MEGSR-LQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKAILKKDIYQKKGHYF 3370
Query: 3468 MRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKER 3527
+R+GD E EYN+NFR Y++T++ NPH+ P T++NF V QGL+ QLL VV E
Sbjct: 3371 IRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLLSTVVTHEV 3430
Query: 3528 PELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVT 3587
P LE+Q+ L+ +I+ L+ELE++ L LL +A GS+LDD ++V+TL SK+T+ E++
Sbjct: 3431 PHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKSKMTSNEIS 3490
Query: 3588 EQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSI- 3646
+++E ++ E R+ Y P A R ++L+F++ D+ I+ MYQFSLD + +F+ S+
Sbjct: 3491 KRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFHQVFVSSVV 3550
Query: 3647 ------------------------------DKSHRSNKLEDRIDYLNDYHTYAVYRYTCR 3676
+ + N L+ I D T ++++
Sbjct: 3551 SKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSAIDMLTKSIFKVVSS 3610
Query: 3677 TLFERHKLLFSFHMCAKILETSGKLNM----------DEYNFFLRGGVVLDREGQM---- 3722
LF KL FSF +C I++ + N+ +E+N FL G++++ + +
Sbjct: 3611 ALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGILINIKSALSQSR 3670
Query: 3723 --------DNPCSSWLADAYWDNITELDK-LTNFHGLMNSFEQYPRDWHLWYTNAA---- 3769
++ WL+D+ W + L F L S W + + A
Sbjct: 3671 LTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWDTFKNSKAVYSL 3730
Query: 3770 ------------------PEKAMLPGEWENACNEM----------QRMLIVRSLRQDRVA 3801
PE+ L E + CN + QR+++V+ LR + +
Sbjct: 3731 ISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLTSFQRLILVKVLRPESLN 3790
Query: 3802 FCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHM-GM 3860
V FI +G+++++ +N+K + S R+PL+ I + G+D T+ LL+ A+ + G
Sbjct: 3791 NSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHGIDLTNILLRFAQELKGT 3850
Query: 3861 AQRFHALSLGQGQAPIAARLLREGVTQGH-WVFLANCHLSLSWMPNLDKLVEQLQVEDP- 3918
+SLG+ QA A L+ + +T+ WVFL NCHL+ S+MP L +VE +
Sbjct: 3851 THHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATSFMPRLCTIVESFNSPNVT 3910
Query: 3919 -HPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQL-----MSEPQFSRC 3972
P FRLWLSS + FPI +L+ +K+ E P+GLK+N+ + + ++E F
Sbjct: 3911 IDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNLLQTFGCTGSGEVTEEIFENP 3970
Query: 3973 SKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETP 4032
+KKLLFSLCFF++V+ ERK + LGWNI Y FN SD V+ +L L
Sbjct: 3971 DCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSDLGVAIKVLENSLRGQPSIS 4030
Query: 4033 WDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSL 4092
W AL+YLI + YGG V D+WD+R L T + FC+ + + + + S+
Sbjct: 4031 WQALRYLIGEVIYGGRVIDNWDKRCLKTLLYK-FCNPEV--------LKDDFSFSRSASI 4081
Query: 4093 ASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTR---AGGQT 4149
Y I LP D PE G HP A + T+ + + L+++QP+ T Q+
Sbjct: 4082 KDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIENLIAMQPKTTTANLMIRPEQS 4141
Query: 4150 REEKVLELAADVKQKIPEMIDYE----GTQKLL---------------ALDPSPL-NVVL 4189
++E V+E+ +D+ +++P ++ E GT L D PL + VL
Sbjct: 4142 KDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMMSSSIWESLSKNLKDHDPLIHCVL 4201
Query: 4190 L----QEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGK-AY 4244
L QEI+R++ L+ I SL DL+ I+G I+++ LEEIFN + VP LW K AY
Sbjct: 4202 LTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELEEIFNSFLNMRVPTLWQKHAY 4261
Query: 4245 PSQKPLAAWTRDLAMRVEQFELWASRARP------------------------------- 4273
S KPL++W DL R+ F WA A
Sbjct: 4262 RSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSE 4321
Query: 4274 -------PVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSW-EFIVSTVDDSN---LV 4322
P +WL F FP FL AVLQ R ++VD+L++ ++S D + V
Sbjct: 4322 NNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALTFTHHVISNTTDKDEKFSV 4381
Query: 4323 YPPK----------------DGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFR 4366
+ PK GV++ GL++EGA W+R+ L ++ P+++ C P I+F
Sbjct: 4382 FMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQKILEDSLPLEMCCDFPDIYFL 4441
Query: 4367 P---------AESRKKSAKGMYSCPCYYYPNR----AGSSDRASFVIGIDLRSGAMTPDH 4413
P A ++ S + CP Y P R A + +F+ + L S P H
Sbjct: 4442 PTKISTKTPNASNQTDSELYAFECPVYQTPERSRILATTGLPTNFLTSVYL-STKKPPSH 4500
Query: 4414 WIKRGTALL 4422
WI ALL
Sbjct: 4501 WITMRVALL 4509
Score = 709 bits (1830), Expect = 0.0
Identities = 453/1381 (32%), Positives = 720/1381 (52%), Gaps = 164/1381 (11%)
Query: 1019 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV 1078
H+ +L+Q E +NK LLE+ ++ + +++ P +EE +
Sbjct: 789 HMSHTLIQSVIEKKNK-----------NLLEV---VESSLQQLECDPTEIEEFLEHFIFL 834
Query: 1079 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQM- 1137
+A+ ++ +E + + + +++ + +++ + + + +FQ LL Q+
Sbjct: 835 NAISSKISKLEKEFLTMSQLYSVAKHHQIHISEEQI----------AIFQVLLLKFSQLK 884
Query: 1138 --LKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVG---YMSALDQITQVRAM 1192
+K K T + D+ + L D G+ + + + A Q++ M
Sbjct: 885 SSMKLSKINKDTAITKFRDNLEACISGLHVDV---GNLKAKIRTPLLLCAGTQVSTAMEM 941
Query: 1193 LMAMREEENSLRA--------------------NLGIFKIEQPPSKDLQNLEKELDALQQ 1232
+ + E SL ++ + +I Q ++ ++E +L ++
Sbjct: 942 IQTLSGEAASLTNKAKAYSHYQDCFSDSQSHMHSVNVEEITQIVLSEISDIEGDLTLRKK 1001
Query: 1233 IWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSK 1292
+WE +W+ EW+ + E+++ L ++ L K +++ +
Sbjct: 1002 LWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEKGLPKS--DMVTHLKQV 1059
Query: 1293 IEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIG 1352
+ +FK+ +P+I L NP L+ RHW+ +++ I + + ++ +E ++ L M Q+ +I
Sbjct: 1060 VTEFKQELPIIIALGNPCLKPRHWEALQEIIGKSVPLD-KNCKVENLLALKMFQYENEIN 1118
Query: 1353 EISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHR--LRGTEEVFQALEDNQVAL 1410
++S SAT E A+E L I W+ T L ++ + + + + +++ LE++QV L
Sbjct: 1119 DMSTSATNEAALEKMLFKIIDFWNTTPLPLILHHTEIYSIFIIPSIDDISAQLEESQVIL 1178
Query: 1411 STMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNES 1470
+T+K S + + V+ W++ L+L +E + QR W+YLE +F +IR+QLP E+
Sbjct: 1179 ATIKGSPHIGPIKDLVNEWDQNLTLFSYTLEEWMNCQRNWLYLEPVFHSSEIRRQLPAET 1238
Query: 1471 TLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHI 1530
LF QV S WK IM ++ NAL+ T G+L+ L N LE I+KSL+ YLE KR I
Sbjct: 1239 ELFSQVISMWKKIMSKIQNKQNALQITTSAGVLEILQNCNIHLEHIKKSLEDYLEVKRLI 1298
Query: 1531 FPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRI--QKVGGPSSKWEAVGMFS 1588
FPRFYFLSN +LL+IL SRNPE+VQPHL KCF+NIK L I Q +G P+ K + S
Sbjct: 1299 FPRFYFLSNAELLDILADSRNPESVQPHLVKCFENIKQLLIWKQDIGPPAVKM----LIS 1354
Query: 1589 GDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAG 1648
+GE + + + VE WL +VE++M L K+++++
Sbjct: 1355 AEGEGLVLPKKIRVRSAVEQWLVNVEKSMFDVL----------------KKERYIYNI-- 1396
Query: 1649 QVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLK 1708
+++ SQI + D K +++ R +K+ KV + + +
Sbjct: 1397 -ILLFQSQIMFYNDCVKSFVSSYSR--EKLEKVHAGLMCHLEEVADLVVLDTSNSRTKAI 1453
Query: 1709 IVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYE 1768
+ AL+ + +H RD++ L + + F+W L++ W + C + Q N F Y YE
Sbjct: 1454 LGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNASFTYGYE 1513
Query: 1769 YLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVN 1828
YLG + RLVITPLTDRC++TL ALHL+ GG P GPAGTGKTETVKDL K+LG + +V N
Sbjct: 1514 YLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKSLGKHCVVFN 1573
Query: 1829 CSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHF 1888
C E LDYK + + + GL Q+GAW CFDEFN I++EVLSV+A QIL I +A F
Sbjct: 1574 CFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILTIKAAKDNYSARFVL 1633
Query: 1889 DGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGN 1948
+G EI + SC +FITMNP Y G ELP+NLKS+FRP+AM+VP +IAEIILF GF +
Sbjct: 1634 EGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKS 1693
Query: 1949 CKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLL--- 2005
L+ K+ LY LA +QLS+QDHY+FGLR+L +L AG K+R L++ + L+
Sbjct: 1694 ANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCLSEADETLIVIE 1753
Query: 2006 SMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLT 2065
++R+ ++ K D PLF I+ D+FP + + ++ L + + + +GLQ+
Sbjct: 1754 AIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSSQKE 1813
Query: 2066 KVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFP------ 2119
K+ Q Y M+VG TG GKT RIL+ +L+ L A +F V E
Sbjct: 1814 KIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIA---DFLSVAERKSASKIS 1870
Query: 2120 ----------LNPKALSLGELYGEYDLSTNEWTDGIL----------------------- 2146
LNPK ++L ELYG+ D +T EWTDG+L
Sbjct: 1871 ERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDIDLR 1930
Query: 2147 --------SSVMRTACADEKP---------------------DEKWILFDGPVDTLWIEN 2177
S+V + +D D +WI+ DGPVDT W+EN
Sbjct: 1931 LKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVKIPENHNFDWQWIILDGPVDTFWVEN 1990
Query: 2178 MNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPY 2237
+NSV+DD + L L N ERIA+ ++ ++FEV++L+ ASPATVSRC MVY D DLGW+PY
Sbjct: 1991 LNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWEPY 2050
Query: 2238 VQSWLEKRPK----AEVEPLQRMFEKLINKMLAFKKDNCK-ELVPLPEYSGITSLCKLYS 2292
V+SWL K K + V+ L+ M + + L F ++ K + P+ + + + +LC++
Sbjct: 2051 VKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCRILD 2110
Query: 2293 A 2293
A
Sbjct: 2111 A 2111
Score = 156 bits (394), Expect = 5e-37
Identities = 99/324 (30%), Positives = 164/324 (50%), Gaps = 18/324 (5%)
Query: 2394 DTVRYNYLVSSLVANQNPILLV------------GPVGTGKTSIAQSVLQSLPSSQWSVL 2441
DT+ Y+ + S QN +L+ P + + +L++ V
Sbjct: 2369 DTLLYSEIKKSSSLKQNITILIPETHKTATGSSDNPTKKPEVRTNKKLLKNNDHKGVVVS 2428
Query: 2442 VVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLEL 2501
+N S T+ + +I ++ +RTK ++ F+DD+NMP DM+G+QPPLEL
Sbjct: 2429 TINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPPLEL 2488
Query: 2502 IRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQ 2561
IR +D G YD K T K I+++ ++AA P ISPRL F+++ + P++
Sbjct: 2489 IRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVND---ISPRLLKHFSMLVLPHPSQDI 2545
Query: 2562 IIRIFGTMINQ--KLQDFEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDI 2619
+ IF + + +F EV+ + + +L +Y+ V Q LPTPTK HY+FNLRD+
Sbjct: 2546 LCTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLRDM 2605
Query: 2620 SKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDL 2679
K+ G+L+A++ ++K L++HE RVF DRL+D D F ++S +L + F +
Sbjct: 2606 FKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELENCFQI 2665
Query: 2680 TFHHLCPSKRPPIFGDFLKEPKVY 2703
C K +L + K+Y
Sbjct: 2666 GIDG-CGKKTCATLACYLTDNKLY 2688
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 486 bits (1250), Expect = e-136
Identities = 274/815 (33%), Positives = 438/815 (53%), Gaps = 27/815 (3%)
Query: 3621 LNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFE 3680
+ND+ I PMYQFSL A+ +F +++++ L +R+ L D T++VY+YT R LFE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3681 RHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITE 3740
KL + + +IL + ++N E +F LR V ++ +L+ W +
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVE-----FLSHQAWGAVKV 115
Query: 3741 LDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRV 3800
L + F L E + W + + PEK LP EW+N +QR+ ++R++R DR+
Sbjct: 116 LSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRM 174
Query: 3801 AFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM 3860
+ + F+ LGS+++ L+ + E+S P +P+ FILSPGVDP + +G
Sbjct: 175 TYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGY 234
Query: 3861 A---QRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVED 3917
Q FH +SLGQGQ +A L +GHWV L N HL W+ L+K +E+ E+
Sbjct: 235 TFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEE-HSEN 293
Query: 3918 PHPSFRLWLSSIPHPD-----FPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRC 3972
HP FR+++S+ P P P IL+ SIK+T EPP G+ AN+ + ++ C
Sbjct: 294 SHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMC 353
Query: 3973 SKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETP 4032
S+ ++K +LF+LC+FH+V+ ER+KF GWN Y FN D +S N+L +L+ + P
Sbjct: 354 SRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVP 413
Query: 4033 WDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSL 4092
+D L+YL I YGGH+TDDWDRRL TY+ ++ + L LS + +P +
Sbjct: 414 YDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLE---GELSLAPGFPLPGNMDY 470
Query: 4093 ASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAG-GQTRE 4151
Y +YI + P +G HPNA++ ++ LF T+L LQP+ + R G G TRE
Sbjct: 471 NGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATRE 530
Query: 4152 EKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLE 4211
EKV L ++ +++ + + + + +P VV QE R N L + I SL +LE
Sbjct: 531 EKVKALLEEILERVTDEFNIPELMAKVE-ERTPYIVVAFQECGRMNILTREIQRSLRELE 589
Query: 4212 KGIQGLIVMSTSLEEIFNCIFDAHVPPLWG-KAYPSQKPLAAWTRDLAMRVEQFELWASR 4270
G++G + M++ +E + N ++ VP W +AYPS LAAW DL R+++ E W
Sbjct: 590 LGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGD 649
Query: 4271 ARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVW 4330
P WL+GF P FLTA++QS+AR+N +D ++ + ++ + PP++G +
Sbjct: 650 FTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAY 709
Query: 4331 VRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRA 4390
+ GL++EGA WD + + EA+ L MP + + + K+ + +YSCP Y R
Sbjct: 710 IHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRG 769
Query: 4391 GSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSL 4425
++V +L++ P W+ G ALL+ +
Sbjct: 770 -----PTYVWTFNLKT-KENPSKWVLAGVALLLQI 798
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 261 bits (668), Expect = 8e-69
Identities = 339/1668 (20%), Positives = 659/1668 (39%), Gaps = 269/1668 (16%)
Query: 1231 QQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTR 1290
Q+IW + R EN +EWK F + G +++ + + +++
Sbjct: 1019 QRIWHLYRVISENISEWKCMAFAKFSPAMAQEKTEGWLTEAARMSTTLELHS-PVLQHCM 1077
Query: 1291 SKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEK 1350
+ +F+ +PL++ L + + + + + Q E TL Q++ + + ++
Sbjct: 1078 RILGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADR 1137
Query: 1351 IGEISASATKELAIEVALQNIAKTWDVTQLDI------VPY------------------- 1385
I ++ + + + + ++ + + W+ QL + VPY
Sbjct: 1138 INQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWE 1197
Query: 1386 ---KDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEM 1442
KD G L + +++++ LS + A K W + + ++E+
Sbjct: 1198 VVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEV 1257
Query: 1443 ILTVQRQWMYLENIFLGEDIRKQLPNE--STLFDQVNSNWKAIMDRMNKDNNAL------ 1494
LT Q++W++L + +++ Q PN ++ F ++ ++ +M D L
Sbjct: 1258 WLTFQQKWIFLNKVL--HEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPS 1315
Query: 1495 --RSTHHPGL-LDTLIEMNTI-LEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSR 1550
RS + G L L++ ++ LE I SL+ L FPR +FLS+ +L+ +L
Sbjct: 1316 AERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARL 1375
Query: 1551 NPEAVQPHLKKCFDNIKLLRIQKV-----------GGPSSKW--EAVGMFSGDGEYIDFL 1597
Q +++CF ++ + + P+++ EA+ + GE +
Sbjct: 1376 ESCEAQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQ 1435
Query: 1598 HSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLA----------LRKFLNKRDK-----W 1642
+ L + WL +E+ +R+ L +L+ C A K L K++K +
Sbjct: 1436 GPLPLHPDLPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLY 1495
Query: 1643 VKEWAG-------QVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSE 1695
V+ W Q V+ A ++ W A++ + LL A + M ++ +L +
Sbjct: 1496 VQHWIDLVQAFPWQCVLVAEEVVWRAEMEEALLEWGTLA----MVSMHMRKLEVLVNFMR 1551
Query: 1696 AIRGN-----LTKIMRLKIV-ALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYW-- 1747
A R + L + + ++ AL+ + + RD+ + L + + D+ F W+ QL+++
Sbjct: 1552 AQRASQGGQSLPSVRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGS 1611
Query: 1748 ------------------EKDLDD--CVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYM 1787
E L C I F YNYEYLG + + L +R +
Sbjct: 1612 PHIIPKSPLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPAL 1671
Query: 1788 TLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQ 1847
L AL G+ GP G GK V L +ALG ++++ CS ++ + + +G Q
Sbjct: 1672 VLLLALEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQ 1731
Query: 1848 TGAWGCFDEFNRINIEVLSVVA------HQILCILSALAA--------------GLTHFH 1887
GAW ++ +++ +LS + H + L A+ G + F
Sbjct: 1732 GGAWLLLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFE 1791
Query: 1888 FDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFG 1947
+ L + C + + A + +P NL + RP+A+ +PD +AE+ L G G
Sbjct: 1792 KHHVSVRLGYGCLLVLR-----ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMR 1846
Query: 1948 NCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSM 2007
+ +A ++ +SL + +S L LL+ + ++T EE
Sbjct: 1847 DAFQMATRLSKFFSLERELVSGP------LPCRLPLLKQILEDTIRTLNVTKEEPKCQKP 1900
Query: 2008 RDMN-IAKLTSVDAPLFN-----------AIVQDLFPNIELPVID---YGKLRETVEQEI 2052
R + I + + +PLF+ ++ LFP+ + + Y ++ V +E+
Sbjct: 1901 RSLAAIEEAALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEEL 1960
Query: 2053 RDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRIL---QASLSSLCRAGD 2109
+ +GL +P L + QL + + +++G GSGKT W L Q L+++
Sbjct: 1961 QQVGLDPSPDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTST 2020
Query: 2110 PNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEK------- 2162
V L P LS E G + S W GI V+R A +K
Sbjct: 2021 QGCQPVEITHLYPSGLSPQEFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESI 2078
Query: 2163 ----WILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT 2218
WI+ DG + W++++ ++ + L+L +G++IA P LL EV D SP
Sbjct: 2079 GIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTV 2138
Query: 2219 VSRCGMVYTDYADLGWKPYVQSWLEKRP------KAEVEPLQRMFEKLINKMLAFKKDNC 2272
V C +V+ + W+ + + + P V L M E L+ L F C
Sbjct: 2139 VGCCALVWCG-GEQTWQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFL--TC 2195
Query: 2273 KELVPLPEYSG----------ITSLCKLYSAL------ATPENGVNPAD-------GENY 2309
+ + L + G +TS+ ++ +L E P D +++
Sbjct: 2196 QGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSF 2255
Query: 2310 VT------------------------MVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIE 2345
+ + +F+F++IW A + D+++R+
Sbjct: 2256 RSSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSI 2315
Query: 2346 GSF------PNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYN 2399
P V++ V P+ + F + S F+ P++ T R
Sbjct: 2316 SRLSNYPEPPPSALVFDLHVSPEDGTLVPFTGQYLSSHIKGTLGTFH----PSIQTERLL 2371
Query: 2400 YLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIE 2459
Y+V L++ P+LL G TGK++ + +++ +S + S+ + I+
Sbjct: 2372 YVVDLLLSGGQPVLLAGEAATGKSAFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQ 2431
Query: 2460 SRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGS-QPPLELIRLWIDYGFWYDRTKQT 2518
+ + + + S++ ++DL++ D S QP LE +R +D + T +
Sbjct: 2432 GQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMDGTVYAHSTLEL 2491
Query: 2519 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE 2578
+ +A + PG + PRL F ++ + T++ ++ +I L+ F
Sbjct: 2492 QTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFP 2551
Query: 2579 --EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGM-----LRANK 2631
E + + + A+++ + V F+P+P HY F+L +S + + ++
Sbjct: 2552 SVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSR 2611
Query: 2632 DFHD-----------------------TKSSITRLWIHECFRVFSDRL 2656
F D ++ RLW+HE R F DRL
Sbjct: 2612 GFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRL 2659
Score = 145 bits (365), Expect = 1e-33
Identities = 175/755 (23%), Positives = 311/755 (41%), Gaps = 94/755 (12%)
Query: 2712 LKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGN-MLLVGIGGSGRQS 2770
L+ + T+ + LSP L +H+ R+VRV+ +PR + +LL G G+GR +
Sbjct: 2845 LEEQLATSAAQLKLSP-----HLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHT 2899
Query: 2771 LARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFL 2830
LASSIC F + ++ ++ AG+ L + V + + D + L
Sbjct: 2900 AITLASSICQAHFFHLPSGS---EEAILQCLRDASWHAGM-LSQPVALLVPSGV-DLTTL 2954
Query: 2831 EDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVL 2890
+ + +SG P Y + + I H+ + + + + ++V ++LH+
Sbjct: 2955 HRLLALATSGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFF 3014
Query: 2891 CLSPMGDPFRNWIRQYPALV-------NCTTINWFSEWPQEALLEVAEKCLIG-----VD 2938
+ GD + +Q P+ + +I+ + W Q AL +VA+ L G +D
Sbjct: 3015 LI---GDKQAH--KQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSVPLD 3069
Query: 2939 LGT------QENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKL 2992
G+ Q +I VA+ +H S Y + + L VTP +L+ L + L
Sbjct: 3070 DGSWKYPDLQASIP-SVAKAMALIHLSATHYHEHLCPALP---LVTPKTFLDFLDTFLML 3125
Query: 2993 LGEKRQELLAQANKLRTGLFKIDETREKVQ--------VMSLE--LEDAKKKVAEFQKQC 3042
++Q +L NK + ++ R ++ + LE L+D+ K ++ FQ+Q
Sbjct: 3126 ---QQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQL 3182
Query: 3043 EEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRAL 3102
E+ ++ QQ E Q+ + E +A + QA + + + +A + L
Sbjct: 3183 EQSKLLYKQQLEECRHQENLI----ENLARQRDALQAQREAFLEQMSKAF------LEPL 3232
Query: 3103 ESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKD 3162
L D EI+SY PP V V A+ L +E WA AK+ L ++F + L+ F K+
Sbjct: 3233 SQLQVADFEEIRSYRAPPESVVRVTDAMCDLFHHETGWASAKQLLCTEDFYQELVFFPKE 3292
Query: 3163 NISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNA 3222
I+D L K+ P + VS A SL W+ A+ YG + P + +
Sbjct: 3293 KITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQ 3352
Query: 3223 ALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGML 3282
A L +QA L Q + +E E L K ++ A + K + + +
Sbjct: 3353 VEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQASHNCVAKTLSQAQCGQYHKWPM 3412
Query: 3283 VSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIW 3342
+ L W +Q L+ + GD LL +A + Y+GPF R E++++ W+
Sbjct: 3413 KAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDE-WLALCR 3471
Query: 3343 ELQVPCSPS---------------------------FAIDNFLCNPTKVRDWNIQGLPSD 3375
Q P F+I + L + ++ W+ P
Sbjct: 3472 GFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQA 3531
Query: 3376 AFSTENGIIVTRGN-----RWALMIDPQAQALKWI 3405
+ G+++ RW L++DP +AL W+
Sbjct: 3532 KSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWL 3566
Score = 99.4 bits (246), Expect = 7e-20
Identities = 215/1059 (20%), Positives = 375/1059 (35%), Gaps = 128/1059 (12%)
Query: 3428 LEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITT 3487
L+ A G PVLL NV+ L + LL R + F Y++T
Sbjct: 3678 LQEAAACGLPVLLTNVE----------LGLGCEELQW-LLQREQLSPPQVQPGFCLYLST 3726
Query: 3488 KLS----NPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAA 3543
LS E +++ + + LE Q+L ++ +E PELE + L I
Sbjct: 3727 TLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALD 3786
Query: 3544 GKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLA 3603
+ ++ E+ +L +L + + + ++ ++ E E ++ +
Sbjct: 3787 TCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVL 3846
Query: 3604 REAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSID--KSHRSNKLEDRIDY 3661
YRP + L+ + + P++ S + ++++ ++D K N ED +
Sbjct: 3847 WAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASH 3906
Query: 3662 LNDYHTYAVYRY---TCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR 3718
L + + T L L +L+ +GK + E L G+
Sbjct: 3907 LLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASELE-RLALWPGLAASP 3965
Query: 3719 EGQMDNPCS-----SWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKA 3773
P S +WL W L+ L F GL S + W + + ++
Sbjct: 3966 STVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLG 4025
Query: 3774 MLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTP 3833
PG + +Q++++ R LR + +A + F + LG R ++ + S
Sbjct: 4026 PAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLG-RPLDENTYAPTMPFKHSQA 4084
Query: 3834 RSPLVFILSPGVDPTSALLQLAEHMGMAQRFH-------ALSLGQ---GQAPIAARLLRE 3883
P++ +L P P++ L L +A ++ ++LG + L +
Sbjct: 4085 TQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQ 4144
Query: 3884 GVTQGHWVFLANCHLSLSWMPNLDKLV----------------------EQLQVEDPHPS 3921
+ +GHW+ L NCHL W L +L+ E V H
Sbjct: 4145 AMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRD 4204
Query: 3922 FRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKL 3981
FRLWL + + M + L+ + + Q P + L
Sbjct: 4205 FRLWLIVPAESSASLPAVLTQHSMPVFWNQSLELGHVLIDSVELAQQVLYMQPPTQALPL 4264
Query: 3982 LFSLCFFHSVLLERKKFLQLGWNIIYG--FNDSDFEVSENLLSLYLDEYEE------TPW 4033
L H +LL R+ +YG S+ L+ L ++ P
Sbjct: 4265 L----LLHGLLLHRQ---------LYGTRLQAHRGRWSQVTLTQVLQTQDQLWASLSNPR 4311
Query: 4034 DALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLS--TPFHRLSALETYF----IP 4087
A++ L A + YGG + D DR L + S S P S L T +
Sbjct: 4312 AAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELR 4371
Query: 4088 KDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITP-TRAG 4146
+ ++A K + LLP P G +++ L L P P +R G
Sbjct: 4372 ELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRG 4431
Query: 4147 GQTREEKVLELAADVKQKIPEMIDY--------EGTQKLLALDPS---PLNVVLLQEIQR 4195
Q E ++ + V +++ + D E L P+ PL VL E
Sbjct: 4432 AQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALE 4491
Query: 4196 YNTLMQTILFSLTDLEKGIQGL-IVMSTSLEEIFNCIFDAHVPPLWGKAYPS-QKPLAAW 4253
+ L+ T+ L L + ++G S + + ++ +P W P+ +P W
Sbjct: 4492 LSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHW 4551
Query: 4254 TRDLAMRVEQFELW------ASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNV----- 4302
R L+ R + + AS P +F LS F P L A+ +A NV
Sbjct: 4552 LRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNF 4611
Query: 4303 --SVDSLSWEFIVSTVD-DSNLVY----------PPKDGVWVRGLYLEGAGWDRKNSCLV 4349
S S+S + ++ +SN ++ P+ G+ + GL + A WD L
Sbjct: 4612 PGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQ 4671
Query: 4350 EAEPMQLVCLMPTIHFRPAESRK----KSAKGMYSCPCY 4384
++ Q L P A + +YSCP Y
Sbjct: 4672 DSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVY 4710
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 58.5 bits (140), Expect = 1e-07
Identities = 251/1254 (20%), Positives = 496/1254 (39%), Gaps = 188/1254 (14%)
Query: 536 DLEPYVAQYSGKARWVHILRRRIDRVMTCLAGAH-----FLPRIGTGKESVHTYQQMVQA 590
++E + K+ +HI+ D++ + + L IG K+ + T Q ++
Sbjct: 755 EVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Query: 591 IDELVR--KTF-----QEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAE 643
D+ + KT Q++ L+++ R++ ++ +S+E FD SL L E
Sbjct: 815 TDQEFQNFKTLHMDFEQKYKMVLEEN--ERMNQEIVNLSKEAQ-----KFDSSLGALKTE 867
Query: 644 IDYWERLLFETPHYVVNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRL 703
+ Y + L E V E L+ EN + R +++ Q +E L
Sbjct: 868 LSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTL 927
Query: 704 LDKKIHPGLKKLHWALKGASAFFITECRIHAS-KVQMIVNEFKASTLTIGWRAQEMSEKL 762
+K LK+L +L+ ++ IH + + + E + L + QE L
Sbjct: 928 TQEK--DDLKQLQESLQIERDQLKSD--IHDTVNMNIDTQEQLRNALESLKQHQETINTL 983
Query: 763 LVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLH--QDVVTIMTNSYEVFKNDGPEIQQQ 820
+IS + V R+L EE+ E + QQK++ + QD+ T + D I+QQ
Sbjct: 984 KSKIS-EEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQ 1042
Query: 821 WMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQV 880
++ + + K L ++ +++ + + Q+ LK +++ ++
Sbjct: 1043 RKIFSL-----------IQEKNELQQMLESVIAEKE-------QLKTDLKENIEMTIENQ 1084
Query: 881 E----FSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK--RKLHREPIQTVVEQDEDI 934
E L+ +V NH D L + KL +E Q + E+ + +
Sbjct: 1085 EELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKL-KEKSQQLQEKQQQL 1143
Query: 935 KKIQTQISSGMT--NNASLLQNYLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIA 992
+Q ++S N L+N LK ++ E E + + Q+LN V I
Sbjct: 1144 LNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETER---LELAQKLNENYEE-VKSIT 1199
Query: 993 RYTEVANNVQKE-ETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELH 1051
+ +V +QK ET + HL+ + + AT L+ ++ +H
Sbjct: 1200 KERKVLKELQKSFET---------ERDHLRGYI-------REIEATGLQTKEELKIAHIH 1243
Query: 1052 TYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIHEQFAILEKY-EVPVE 1110
LKE+ E I +++ E + L+ ++ +IP +HE+ +L EV
Sbjct: 1244 --LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSET 1301
Query: 1111 DSVLEMLDSLNGEWVVFQQTLLDSKQMLK-KHKEKFK------TGLIHSADDFK--KKAH 1161
+ L+ L + T L +M + + EKF+ L D+ K K+A
Sbjct: 1302 QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEAL 1361
Query: 1162 TLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENS----------------LRA 1205
+ D + K H + + Q Q +++ M ++ E + LR
Sbjct: 1362 EVKHD-QLKEHIRETLAKIQE-SQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRI 1419
Query: 1206 N---LGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNE-WKTGRFLILQTETME 1261
LG+ K Q +++++ KE D LQ++ E+ + + E K L+TE
Sbjct: 1420 EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEEL 1479
Query: 1262 TTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRD 1321
AH + + E + + ++I ++ + I+ D++++
Sbjct: 1480 KVAHCCLKEQEETINELRVN----LSEKETEISTIQKQLEAIN------------DKLQN 1523
Query: 1322 EIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNI-AKTWDVTQL 1380
+IQ +++E E F ++QI E+ EK+ E+ A + ALQ+I +K ++T
Sbjct: 1524 KIQEIYEKE-EQFNIKQISEV-----QEKVNELKQFKEHRKAKDSALQSIESKMLELT-- 1575
Query: 1381 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI 1440
+RL+ ++E Q + + + R +A + + D + I V
Sbjct: 1576 ----------NRLQESQEEIQIMIKEKEEM-----KRVQEALQIERDQLKENTKEI--VA 1618
Query: 1441 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP 1500
+M + ++++ +L+ + E K E L +Q + K ++ + +N L H
Sbjct: 1619 KMKESQEKEYQFLKMTAVNETQEKMCEIEH-LKEQFETQ-KLNLENIETENIRLTQILH- 1675
Query: 1501 GLLDTLIEMNTILE--DIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH 1558
+ L EM ++ + D +S++ L+ +R + + L + + V H
Sbjct: 1676 ---ENLEEMRSVTKERDDLRSVEETLKVERDQLKENL---RETITRDLEKQEELKIVHMH 1729
Query: 1559 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR 1618
LK+ + I LR G S K + D E HS D +
Sbjct: 1730 LKEHQETIDKLR----GIVSEKTNEISNMQKDLE-----HS-----------NDALKAQD 1769
Query: 1619 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAK---ERAD 1675
+ +++ LR H+ L++ DK ++ + S +Q + + L K +A+
Sbjct: 1770 LKIQEELRIAHMHLKEQQETIDK-LRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKAN 1828
Query: 1676 KKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKS 1729
+ L +KK+ K SE L K ++ + + L +EI ++ +KL+++
Sbjct: 1829 EHQLITLKKDVNETQKKVSE--MEQLKKQIKDQSLTLSKLEIENLNLAQKLHEN 1880
Score = 43.1 bits (100), Expect = 0.006
Identities = 86/424 (20%), Positives = 177/424 (41%), Gaps = 58/424 (13%)
Query: 2938 DLGTQENIHRKVAQIFV---TMHWSVAQYSQKMLLELRRHNYVTPT------KYLELLSG 2988
DL T ++ ++ Q F T+H Q + +L E R N K+ L
Sbjct: 804 DLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGA 863
Query: 2989 YKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKK---VAEFQKQCEEY 3045
K L K QEL + +++ L ++++ +E+++ L+ +++ + E +Q E
Sbjct: 864 LKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEE 923
Query: 3046 LVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESL 3105
+ + Q+K + + Q+++ +++ + + + Q+ L AL +L++ + +L
Sbjct: 924 VKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTL 983
Query: 3106 NKKDIGEI-------KSYGRPPAQVEIVMQAV-----MILRGNEPTWAEAKRQ--LGEQN 3151
K E+ ++ G + + M + + + + A+ K + +Q
Sbjct: 984 KSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQR 1043
Query: 3152 FIKSLINFDKDNISDKVLKKIGAYCAQ--PDFQPDI------------IGRVSLAAKSLC 3197
I SLI + N ++L+ + A Q D + +I +G + +
Sbjct: 1044 KIFSLIQ--EKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIV 1101
Query: 3198 MWVR--AMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQY 3255
+ A++ G L R + R+ +L+EK L E Q++L V E++ ++K+
Sbjct: 1102 AQEKNHAIKKEGELSRTCD----RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI 1157
Query: 3256 DEKLAQKEELRKKS---EEMEL-KLERAGML------VSGLAGEKARWEETVQGLEEDLG 3305
+E K EL+ K E ME +LE A L V + E+ +E + E +
Sbjct: 1158 NEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERD 1217
Query: 3306 YLVG 3309
+L G
Sbjct: 1218 HLRG 1221
Score = 40.0 bits (92), Expect = 0.052
Identities = 55/283 (19%), Positives = 116/283 (40%), Gaps = 31/283 (10%)
Query: 2998 QELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREAD 3057
Q+L ++++ + + D R + + LE + K+ + E + + E + + +
Sbjct: 1875 QKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSK 1934
Query: 3058 EQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYG 3117
E ++ V EKI+ + I+ + QKDL+++ +E + ++ L KK++
Sbjct: 1935 EHKETVDKLREKISEKTIQISDI----QKDLDKSK---DELQKKIQELQKKEL------- 1980
Query: 3118 RPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKV---LKKIGA 3174
Q+ V + V + + K+Q QN + D ++ K+ L++I
Sbjct: 1981 ----QLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRI 2036
Query: 3175 YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAAL 3234
+ D I + + +R M R V+P++ ++ L E
Sbjct: 2037 VAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTES---- 2092
Query: 3235 AEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLE 3277
LRE +++ L K+Y E E L + S ++E ++E
Sbjct: 2093 ------LREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIE 2129
Score = 37.7 bits (86), Expect = 0.26
Identities = 60/296 (20%), Positives = 125/296 (42%), Gaps = 44/296 (14%)
Query: 2993 LGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQ 3052
L EK QEL A ++L T ++ET++KV E+E KK++
Sbjct: 1818 LQEKIQELKANEHQLITLKKDVNETQKKVS----EMEQLKKQI----------------- 1856
Query: 3053 KREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEA--MRALESLNKKDI 3110
K + K+ +E + LA ++LEE ++E +R +E K +
Sbjct: 1857 --------KDQSLTLSKLEIENLN---LAQKLHENLEEMKSVMKERDNLRRVEETLKLER 1905
Query: 3111 GEIKSYGRPPAQVEIVMQ-----AVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNIS 3165
++K + ++ +Q A M+ + ++ T + + ++ E+ S I D D
Sbjct: 1906 DQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSK 1965
Query: 3166 DKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLC---MWVRAMELYGRLYRVVEPKRIRMNA 3222
D++ KKI + + V+++ K + + E + V ++
Sbjct: 1966 DELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTK 2025
Query: 3223 ALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLER 3278
L + E+ +A+ +++LR + E L+M + Q+ L +E + + + ++K E+
Sbjct: 2026 KLHESLEEIRIVAKERDELRRIKESLKMERDQFIATL--REMIARDRQNHQVKPEK 2079
Score = 36.6 bits (83), Expect = 0.57
Identities = 104/547 (19%), Positives = 211/547 (38%), Gaps = 58/547 (10%)
Query: 838 LNVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIG 897
L ++ + +L K +N + N + VIL ++L+ ++VE L + D
Sbjct: 716 LELEGKITDLQKELNKE--VEENEALREEVILLSELKSLPSEVE------RLRKEIQDKS 767
Query: 898 NHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLK 957
L S K KL E VV ++ ++ + +I + A+ NY
Sbjct: 768 EELHIITS---------EKDKLFSE----VVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Query: 958 TWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETV--TNIQFVLL 1015
T ++ ++ D F +Y+ + + + R + N+ KE +++ +
Sbjct: 815 TDQEFQNFKTLHMD-FEQKYKMV-------LEENERMNQEIVNLSKEAQKFDSSLGALKT 866
Query: 1016 DCSHLKFSLVQHCNEWQNKFATL--LREMAAGRLLELHTYLKENAEKISRPPQTLEELGV 1073
+ S+ L + E Q + + L+E R L T +E + QTLEE+
Sbjct: 867 ELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKT 926
Query: 1074 SLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLD 1133
Q D LK +++ + ++ + + D+V +D+ Q+ L +
Sbjct: 927 LTQEKDDLKQLQESLQIE----------RDQLKSDIHDTVNMNIDT--------QEQLRN 968
Query: 1134 SKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSN-VGYMSALDQITQVRAM 1192
+ + LK+H+E T +++ + H E K F VG D +
Sbjct: 969 ALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQT 1028
Query: 1193 LMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQI-WEIARDWE---ENWNEWK 1248
L A ++ + IF + Q ++ Q LE + +Q+ ++ + E EN E +
Sbjct: 1029 LTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELR 1088
Query: 1249 -TGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLR 1307
G L Q E + + ++ +L++ DR E+ E + K +Q + + +++
Sbjct: 1089 LLGDELKKQQEIVAQEKNHAIKKEGELSRTC-DRLAEVEEKLKEKSQQLQEKQQQLLNVQ 1147
Query: 1308 NPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVA 1367
+ + ++ E + + + L + Q + + E S TKE +
Sbjct: 1148 EEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKE 1207
Query: 1368 LQNIAKT 1374
LQ +T
Sbjct: 1208 LQKSFET 1214
Score = 36.2 bits (82), Expect = 0.74
Identities = 64/306 (20%), Positives = 125/306 (40%), Gaps = 70/306 (22%)
Query: 2995 EKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKR 3054
EK++EL L+ ID+ R V + E+ + +K + + + I ++ R
Sbjct: 1718 EKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELR 1777
Query: 3055 EADEQQKAVTANSEKI-AVEEIKCQALADNAQKDLEEALPALEEAMRALESLN------K 3107
A K +K+ + K L+ N QKDLE + L+E ++ L++ K
Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLS-NMQKDLENSNAKLQEKIQELKANEHQLITLK 1836
Query: 3108 KDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDK 3167
KD+ E + + +++E + K+Q+ +Q+ S + + N++ K
Sbjct: 1837 KDVNETQ---KKVSEME-----------------QLKKQIKDQSLTLSKLEIENLNLAQK 1876
Query: 3168 VLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQL 3227
+ + + KS+ M+ L RV E ++ + L
Sbjct: 1877 LHENLE------------------EMKSV------MKERDNLRRVEETLKLERDQLKESL 1912
Query: 3228 REKQAALAEAQEKL-------REVAEKLEMLKKQYDEKLAQ-----------KEELRKKS 3269
+E +A E Q++L +E E ++ L+++ EK Q K+EL+KK
Sbjct: 1913 QETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKI 1972
Query: 3270 EEMELK 3275
+E++ K
Sbjct: 1973 QELQKK 1978
Score = 33.9 bits (76), Expect = 3.7
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 3218 IRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLE 3277
+ + + L+++ E E LRE L LK E ++E++ KSEE+ +
Sbjct: 716 LELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITS 775
Query: 3278 RAGMLVSGLAGEKARWEETVQGLEEDLG 3305
L S + +++R VQGL E++G
Sbjct: 776 EKDKLFSEVVHKESR----VQGLLEEIG 799
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 58.2 bits (139), Expect = 2e-07
Identities = 79/325 (24%), Positives = 142/325 (43%), Gaps = 36/325 (11%)
Query: 2995 EKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQC-EEYLVIIVQQK 3053
E+ + + ++R + E R++++ + ++++ E +K+ EE I ++K
Sbjct: 305 ERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 364
Query: 3054 READEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEI 3113
R A+E+Q+A EK VEE K K LEE A++E E + +K G
Sbjct: 365 RAAEERQRARAEEEEKAKVEEQK-------RNKQLEEKKHAMQETKIKGEKVEQKIEG-- 415
Query: 3114 KSYGRPPAQVEIVMQAVMILRGNEP-TWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKI 3172
K AQ + + AV+ +G E T +AKR+ +++ F K+ I D+ +KK
Sbjct: 416 KWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQED----KPTFKKEEIKDEKIKK- 470
Query: 3173 GAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPK----RIRMNAALAQLR 3228
D +P + + K V++ +++ + R A++
Sbjct: 471 -------DKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 523
Query: 3229 EKQAALAEAQEKLREV--------AEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAG 3280
+ A EA ++L E+ +E+ E LK++ E + EEL+KK EE LE
Sbjct: 524 AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 583
Query: 3281 M-LVSGLAGEKARWEETVQGLEEDL 3304
A K R EE + L+E++
Sbjct: 584 QRRKQEEADRKLREEEEKRRLKEEI 608
Score = 35.0 bits (79), Expect = 1.7
Identities = 26/93 (27%), Positives = 50/93 (53%), Gaps = 7/93 (7%)
Query: 2994 GEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQK 3053
G++ +EL + + + F ++ ++K Q +LELE+ KKK E +K EE +Q+
Sbjct: 533 GKRLEELRRRRGETESEEF--EKLKQKQQEAALELEELKKKREERRKVLEE-----EEQR 585
Query: 3054 READEQQKAVTANSEKIAVEEIKCQALADNAQK 3086
R+ +E + + EK ++E + A+ A+K
Sbjct: 586 RKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 618
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 54.3 bits (129), Expect = 3e-06
Identities = 74/351 (21%), Positives = 148/351 (42%), Gaps = 52/351 (14%)
Query: 2969 LELRRHNYVTPTKYLELLSGYKKL-----------LGEKRQELLAQANKLRTGLFKIDET 3017
LE H K ++ L G ++ L E+ QEL AQ+++ I +
Sbjct: 1562 LEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQ-------IHDL 1614
Query: 3018 REKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKC 3077
V++ EL++ ++V ++Q EE ++ + + + + E+I V E +
Sbjct: 1615 ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQR 1674
Query: 3078 QALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVE--IVMQAVMILRG 3135
++DLE+ +L E R L + ++ + E G+ P++ + + +ILR
Sbjct: 1675 TRQTKILEEDLEQIKLSLRERGRELTT-QRQLMQERAEEGKGPSKAQRGSLEHMKLILRD 1733
Query: 3136 NEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKS 3195
E + + E +K + + KV S
Sbjct: 1734 KEKEVECQQEHIHELQELKDQLEQQLQGLHRKV-----------------------GETS 1770
Query: 3196 LCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREK--QAALAEAQEKLREVAEKLEMLKK 3253
L + R E+ VV ++++ +L+E+ Q+ L EAQ L + ++LE L++
Sbjct: 1771 LLLSQREQEI------VVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1824
Query: 3254 QYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDL 3304
+ + Q+E +++K++ ++ LE+A M + GE +E + LEE+L
Sbjct: 1825 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEEL 1875
Score = 46.6 bits (109), Expect = 6e-04
Identities = 73/341 (21%), Positives = 136/341 (39%), Gaps = 36/341 (10%)
Query: 2992 LLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQ 3051
LL ++ + + LR L K+ R+ + +++L+ +V K+ E ++ +
Sbjct: 418 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQG---EVDSLSKERE----LLQK 470
Query: 3052 QKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIG 3111
+ E +Q + + + ++ ++ Q D+AQ EE L A+R E L + +G
Sbjct: 471 AREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMG 530
Query: 3112 EIKSYGRPPAQVEIVMQAVMI------LRGNEPTWAEAKRQLGEQNF--IKSLINFDKDN 3163
+++ + +A+ L E T A EQ+ + S N K
Sbjct: 531 LEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTE 590
Query: 3164 ISDKVLKKIGAYCAQPDFQPDIIG------RVSLAAKSLCMWVRAMELYGRLYRVVEPKR 3217
++D + D +G ++ +S+C + A E +V +
Sbjct: 591 VADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEA 650
Query: 3218 IRMNAAL--------AQLR-------EKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQK 3262
+ AL AQL+ E QA L + QE+ E+ +KL + Q + Q
Sbjct: 651 EKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQL 710
Query: 3263 EELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEED 3303
E+L ++++ E L RA L EKA E +Q +E D
Sbjct: 711 EQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERD 751
Score = 43.9 bits (102), Expect = 0.004
Identities = 87/419 (20%), Positives = 168/419 (40%), Gaps = 63/419 (15%)
Query: 2943 ENIHRKVAQ--IFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL 3000
+ +HRKV + + ++ Q+ L E R + L ++ L ++ QEL
Sbjct: 1760 QGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQEL 1819
Query: 3001 LAQANKLRTGLFKIDETREKVQVMSLELEDA----KKKVAEFQ------KQCEEYLVI-- 3048
A + + + + +EK + LE A K++ E Q ++ EE L +
Sbjct: 1820 EALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEG 1879
Query: 3049 ---------IVQQKREADEQQKAVTANSEKIAVE----EIKCQALADN------AQKDLE 3089
+ + E+ EQ+KA+ A ++ A + E++ +AL D+ K+ +
Sbjct: 1880 RRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERD 1939
Query: 3090 EALPAL----------EEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPT 3139
+ L AL EEA RA ++ +G K++ + + +++ + R E +
Sbjct: 1940 QELEALRAESQSSRHQEEAARARAEALQEALG--KAHAALQGKEQHLLEQAELSRSLEAS 1997
Query: 3140 WAEAKRQL----GEQNFIKSLINFDKDNISDKVLK------KIGAYCAQPDFQ-PDIIGR 3188
A + L ++ + + I D+ L+ ++ AQ D + R
Sbjct: 1998 TATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQER 2057
Query: 3189 VSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK---LREVA 3245
L KSL V+ + + E + + +RE Q LA+ +++ LRE
Sbjct: 2058 EQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQ 2117
Query: 3246 EKLEMLKKQYDEKLAQKEELRKKSEEMELKLER-AGMLVSGLAGEKAR---WEETVQGL 3300
++ + + K + EE K + +E +L+R L + L +AR W E Q L
Sbjct: 2118 QRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDL 2176
Score = 39.7 bits (91), Expect = 0.067
Identities = 81/382 (21%), Positives = 164/382 (42%), Gaps = 46/382 (12%)
Query: 2942 QENIHR------KVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGE 2995
QE+IH ++ Q +H V + S +LL R V + L+ +L
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETS--LLLSQREQEIVVLQQQLQEAREQGEL--- 1796
Query: 2996 KRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAE----FQKQCEEYLVIIVQ 3051
K Q L +Q ++ + L + D+ E +Q + + +++V E Q E+ + + +
Sbjct: 1797 KEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKE 1856
Query: 3052 QKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIG 3111
+ E + ++ E++AVE + QAL + DL E+A+ AL+ +
Sbjct: 1857 RHGELQDHKEQARRLEEELAVEGRRVQAL-EEVLGDLRAESREQEKALLALQQQCAEQAQ 1915
Query: 3112 EIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKK 3171
E +VE R + +W +A+ L E++ + L ++ S + ++
Sbjct: 1916 E--------HEVET--------RALQDSWLQAQAVLKERD--QELEALRAESQSSRHQEE 1957
Query: 3172 IGAYCAQPDFQPDIIGRV--SLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLRE 3229
A A+ + + +G+ +L K + +A EL L + ++A A R+
Sbjct: 1958 --AARARAEALQEALGKAHAALQGKEQHLLEQA-ELSRSLEASTATLQASLDACQAHSRQ 2014
Query: 3230 KQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLER--AGMLVSGLA 3287
+ AL + ++++ + + +Q + LAQ++E + +E E LE+ A + +
Sbjct: 2015 LEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMI 2074
Query: 3288 GEK-----ARWEETVQGLEEDL 3304
EK R EE ++GL + +
Sbjct: 2075 QEKQNLGQEREEEEIRGLHQSV 2096
Score = 37.0 bits (84), Expect = 0.44
Identities = 61/328 (18%), Positives = 137/328 (41%), Gaps = 48/328 (14%)
Query: 2993 LGEKRQELLAQANKLRTGLFKIDETREKVQVMS------LELEDAKKKVAEFQKQCEEYL 3046
L ++ EL + + +T + I RE+ + + ++LE K++V+ L
Sbjct: 880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVS--------LL 931
Query: 3047 VIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLN 3106
++Q ++E + + + + + V+++K Q Q L+EA L+EA R +
Sbjct: 932 ETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQ----H 987
Query: 3107 KKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISD 3166
+ D+ ++ Q ++ +Q + ++ + ++L EQ + L + N
Sbjct: 988 RDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQ 1047
Query: 3167 KVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQ 3226
K L++ + + + ME RL + E IR A
Sbjct: 1048 KELER----------------------EKASLTLSLMEKEQRLLVLQEADSIRQQELSAL 1085
Query: 3227 LREKQAALAEAQEKLREVAEKLEMLKKQYDEK----LAQKEELRKKSEEMELKLERAGML 3282
++ Q EAQ + +E++ ++E+L+++ EK LAQ+ +L ++ E + ++
Sbjct: 1086 RQDMQ----EAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRAS 1141
Query: 3283 VSGLAGEKARWEETVQGLEEDLGYLVGD 3310
+ + A+ + ++ E L L +
Sbjct: 1142 LWAQEAKAAQLQLRLRSTESQLEALAAE 1169
Score = 36.6 bits (83), Expect = 0.57
Identities = 83/357 (23%), Positives = 148/357 (41%), Gaps = 66/357 (18%)
Query: 2992 LLGEKRQELLAQA-NKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIV 3050
LL E +A A +KL L+K +TR+ ++ +LE+ + E +K
Sbjct: 1232 LLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEE-RLTDTEAEKS--------- 1281
Query: 3051 QQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALES-LNKKD 3109
Q E + Q+ ++ N E+ + E K Q LE L L E M +L+S L + +
Sbjct: 1282 QVHTELQDLQRQLSQNQEEKSKWEGK--------QNSLESELMELHETMASLQSRLRRAE 1333
Query: 3110 IGEIKSYGRPP----------AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINF 3159
+ +++ G AQVE + AV+ R + L L N
Sbjct: 1334 LQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNE 1393
Query: 3160 DKDNISDKV--LKKIGAY-CAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPK 3216
+ ++ ++ L++ G AQ + ++L ++L +E + +E +
Sbjct: 1394 EVESERERAQALQEQGELKVAQGKALQE---NLALLTQTLAEREEEVETLRGQIQELEKQ 1450
Query: 3217 RIRMNAALAQL------REKQAALAEAQ----EKLREVAEKLEMLKKQYDEKLA-QKEEL 3265
R AAL L R ++ L + Q EK R V E L M ++ ++KL Q+E++
Sbjct: 1451 REMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQI 1510
Query: 3266 RKKSEEME----------LKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCL 3312
R+ ++ E L+LE+ ++ G+ VQ L++ L L +CL
Sbjct: 1511 RELEKDRETQRNVLEHQLLELEKKDQMIESQRGQ-------VQDLKKQLVTL--ECL 1558
>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
Length = 1113
Score = 52.4 bits (124), Expect = 1e-05
Identities = 68/318 (21%), Positives = 138/318 (43%), Gaps = 32/318 (10%)
Query: 3014 IDETREKVQVMSLELEDAKKKVAEFQKQCE---EYLVIIVQQKREADEQQKAVTANSEKI 3070
ID R ++ ++E++ + + + +C+ E + +Q K E+ E+ ++TA E
Sbjct: 414 IDHLRRELDNRNMEVQRLEALLKALKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEST 473
Query: 3071 ------AVEEIKCQALA-DNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQV 3123
VEE+ + + +++++ + + +L+E RA+E+ N +I +++S +V
Sbjct: 474 KEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEATNA-EITKLRS------RV 526
Query: 3124 EIVMQAVMILRG------NEPTWAEA-KRQLGEQNFIKSLINFDKDNISDKVL---KKIG 3173
++ +Q + L+ N T EA K Q+ E++ + ++ +N++ V + G
Sbjct: 527 DLKLQELQHLKNEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAG 586
Query: 3174 AYCAQPDFQPDIIGRVSLAAKSLCMW-----VRAMELYGRLYRVVEPKRIRMNAALAQLR 3228
A + I + K L + + EL R+ + K +NA +LR
Sbjct: 587 AMQVEKAQLEKEINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646
Query: 3229 EKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAG 3288
+ E + L EV L +E K R KSEEME+ + M +
Sbjct: 647 AVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQS 706
Query: 3289 EKARWEETVQGLEEDLGY 3306
E + T++ +E G+
Sbjct: 707 ELEQTRNTLKSMEGSDGH 724
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 52.4 bits (124), Expect = 1e-05
Identities = 78/357 (21%), Positives = 152/357 (42%), Gaps = 56/357 (15%)
Query: 2998 QELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKRE-A 3056
++ A L L K + E+V+ +E K+ AEFQ Q E+ L+ + ++K+E
Sbjct: 963 EQYQAMVTSLEESLNKEKQVTEEVRK---NIEVRLKESAEFQTQLEKKLMEVEKEKQELQ 1019
Query: 3057 DEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPAL-----------EEAMRALESL 3105
D++++A+ + ++++ + ++ + Q+ L+ A AL E+A A+E+
Sbjct: 1020 DDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQ 1079
Query: 3106 NKKD------IGEIKSYGRPPAQV-----------EIVMQAVMILRGNEPTWAEAKRQLG 3148
NK + ++++ QV E +A L + +W E +R L
Sbjct: 1080 NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLK 1139
Query: 3149 EQ-----------NFIKSLINFDKDNISDKVLKKIGAYCAQP-DFQPDIIGRVSLAAKSL 3196
++ L++ + +SDKV+ + P + G+ +
Sbjct: 1140 DEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEI 1199
Query: 3197 CMWV-RAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQY 3255
++ R E+ + V + + +R + L + L E Q+ L EK+++ K
Sbjct: 1200 LRFIRREKEIAETRFEVAQVESLRYRQRVELLERE---LQELQDSLNAEREKVQVTAK-- 1254
Query: 3256 DEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCL 3312
+AQ EEL KK+E M + +E M L EK R E+ +Q ++ + L D L
Sbjct: 1255 --TMAQHEELMKKTETMNVVMETNKM----LREEKERLEQDLQQMQAKVRKLELDIL 1305
Score = 41.2 bits (95), Expect = 0.023
Identities = 72/340 (21%), Positives = 144/340 (42%), Gaps = 37/340 (10%)
Query: 2996 KRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKRE 3055
+ +EL+ + + + RE+ + + +L+ + KV + + L I+ Q+
Sbjct: 1258 QHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLE------LDILPLQEAN 1311
Query: 3056 ADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRAL--ESLNKKDIGEI 3113
A+ +K+ +EK +EE + A N ++ P EE + L + ++ K I ++
Sbjct: 1312 AELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQL 1371
Query: 3114 -KSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKD----NISDKV 3168
+ GR A++ ++ L N+ K L + K I D D +I +KV
Sbjct: 1372 TEEIGRLKAEIA---RSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKV 1428
Query: 3169 -----LKKIGAYC--------AQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEP 3215
+KKIG AQ D + + S + + V+ M+ E
Sbjct: 1429 KTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAET 1488
Query: 3216 KRIRMNAALAQLR----EKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEE 3271
K + + + L+ EK+ QE+ ++ +L L++ ++ Q+E+LR++ E
Sbjct: 1489 KSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITE 1548
Query: 3272 MELKLERAGML----VSGLAGEKARWEETVQGLEEDLGYL 3307
E K +A + ++ LAG K + + + L++ G L
Sbjct: 1549 KEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGAL 1588
Score = 36.6 bits (83), Expect = 0.57
Identities = 72/332 (21%), Positives = 131/332 (39%), Gaps = 44/332 (13%)
Query: 2993 LGEKRQELLA----QANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVI 3048
L K ELLA + N++ ++ +E+V + ++ K QK E+ L
Sbjct: 201 LKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 260
Query: 3049 IVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNK- 3107
+ +EA EQQ ++ IK L +A D E E RA+E L+K
Sbjct: 261 L----KEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSE---AKSNELTRAVEELHKL 313
Query: 3108 -KDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISD 3166
K+ GE A I + + + + E ++G + + +N +D
Sbjct: 314 LKEAGE--------ANKAIQDHLLEVEQSKDQMEKEMLEKIGR-------LEKELENAND 358
Query: 3167 --KVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGR--------LYRVVEPK 3216
K+ GA ++ + + + AK + ++ ELY L +E K
Sbjct: 359 LLSATKRKGAILSEEELAA-MSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENK 417
Query: 3217 RIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKL 3276
RI N L ++ ++ A A ++ RE E+ + KL E+ K+ + ++
Sbjct: 418 RI--NKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKL---EQAMKEIQRLQEDT 472
Query: 3277 ERAGMLVSGLAGEKARWEETVQGLEEDLGYLV 3308
++A S L + R E V+ L + + L+
Sbjct: 473 DKANKQSSVLERDNRRMEIQVKDLSQQIRVLL 504
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens]
Length = 1116
Score = 51.6 bits (122), Expect = 2e-05
Identities = 70/326 (21%), Positives = 140/326 (42%), Gaps = 44/326 (13%)
Query: 2968 LLELRRHNYVTPTKYLELLSGYKKL---LGEKRQELLAQANKLRTGLFKIDETR------ 3018
LL+L+ H + L+ S K L L +K++E L ++L+ E R
Sbjct: 675 LLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS 734
Query: 3019 EKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQ 3078
+++Q + E+ K + ++ Q + + L I+ + + E +++ K + ++ + K
Sbjct: 735 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVA 794
Query: 3079 ALADNAQKDLEEALPALEEAMRALESLN-----------KKD--IGEIKSYGRPPAQVEI 3125
L Q + +++ LEEA R ++LN KKD I E++ R V+I
Sbjct: 795 NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR--ESVQI 852
Query: 3126 VMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDI 3185
+ M+L E A++Q+ E + + +++ K+
Sbjct: 853 TAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSST-------------- 898
Query: 3186 IGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVA 3245
+ SLA K + E L V+E K+ + AA+++ ++ AL E ++
Sbjct: 899 --QQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALLELSSSKKKTQ 955
Query: 3246 EKLEMLKKQYD---EKLAQKEELRKK 3268
E++ LK++ D ++L Q+ + R K
Sbjct: 956 EEVAALKREKDRLVQQLKQQTQNRMK 981
Score = 38.9 bits (89), Expect = 0.11
Identities = 26/101 (25%), Positives = 53/101 (52%), Gaps = 13/101 (12%)
Query: 3215 PKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLK-------KQYDEKLAQKEELRK 3267
P + A + K + ++ + LR++ E+++MLK ++ +E++ Q E R
Sbjct: 372 PDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRS 431
Query: 3268 KSEEMELKLERAGMLVSGLAGEKARWEE---TVQGLEEDLG 3305
S+ M+ K+E+ L L+ ++A+WEE GL+ ++G
Sbjct: 432 HSKFMKNKVEQ---LKEELSSKEAQWEELKKKAAGLQAEIG 469
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 51.6 bits (122), Expect = 2e-05
Identities = 70/326 (21%), Positives = 140/326 (42%), Gaps = 44/326 (13%)
Query: 2968 LLELRRHNYVTPTKYLELLSGYKKL---LGEKRQELLAQANKLRTGLFKIDETR------ 3018
LL+L+ H + L+ S K L L +K++E L ++L+ E R
Sbjct: 647 LLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS 706
Query: 3019 EKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQ 3078
+++Q + E+ K + ++ Q + + L I+ + + E +++ K + ++ + K
Sbjct: 707 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVA 766
Query: 3079 ALADNAQKDLEEALPALEEAMRALESLN-----------KKD--IGEIKSYGRPPAQVEI 3125
L Q + +++ LEEA R ++LN KKD I E++ R V+I
Sbjct: 767 NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR--ESVQI 824
Query: 3126 VMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDI 3185
+ M+L E A++Q+ E + + +++ K+
Sbjct: 825 TAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSST-------------- 870
Query: 3186 IGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVA 3245
+ SLA K + E L V+E K+ + AA+++ ++ AL E ++
Sbjct: 871 --QQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALLELSSSKKKTQ 927
Query: 3246 EKLEMLKKQYD---EKLAQKEELRKK 3268
E++ LK++ D ++L Q+ + R K
Sbjct: 928 EEVAALKREKDRLVQQLKQQTQNRMK 953
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 50.4 bits (119), Expect = 4e-05
Identities = 72/344 (20%), Positives = 149/344 (43%), Gaps = 21/344 (6%)
Query: 2969 LELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLEL 3028
LE + N T+ + LS K E++++L N++ + + +T EK+Q ++
Sbjct: 901 LEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 3029 EDAKK-KVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKD 3087
+A + E Q Q +EY ++ E Q K T +EK + +K Q +++
Sbjct: 961 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEE 1020
Query: 3088 LEEALPALEEAM--RALESLNKKDIG---EIKSYGRPPAQVEIVMQAVMILRGNEPTWAE 3142
L + A +EA+ R L KD+ E KS+ + + +V Q + E E
Sbjct: 1021 LRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDD-RSRLVKQMEDKVSQLE---ME 1076
Query: 3143 AKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRA 3202
+ + + + I+ ++ + + + A+ D + D ++SL ++ + R
Sbjct: 1077 LEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECD---KISLERQNKDLKSRI 1133
Query: 3203 MELYGRLYRVVEPKRIRMNAALAQLREK----QAALAEAQEKLREVAEKLEMLKKQYDEK 3258
+ L G E ++M A +A+L ++ + A Q R + K++ L Q D++
Sbjct: 1134 IHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDE 1193
Query: 3259 ----LAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ 3298
QK++L + + M+ ++E A + L K + + ++
Sbjct: 1194 HLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELE 1237
Score = 44.3 bits (103), Expect = 0.003
Identities = 70/345 (20%), Positives = 146/345 (42%), Gaps = 22/345 (6%)
Query: 2960 VAQYSQKMLLELRRHNYVTPTK--YLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDET 3017
VA+ +++ LE++ + + L + EK +E +L ++ +
Sbjct: 623 VAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKN 682
Query: 3018 REKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKC 3077
E++ + +E E + ++ + Q Q E + KR D ++ A+ + A ++++
Sbjct: 683 LEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQ-AKQDLQD 741
Query: 3078 QALADNAQKDL----EEALPALEEAMRALESLNKKDIGEIKSYGRPPAQ-----VEIVMQ 3128
+A Q+DL E L AL+ A++ S + +++ ++K Q VE +
Sbjct: 742 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 3129 AVMILRGNEPTWAEAKRQLGEQNFIKSLI--NFDKDNISDKVLKKIGAYCAQPDFQPDII 3186
V +L T + Q G + +K L N S+++ +++ Q + D+
Sbjct: 802 NVEVLASRSNT--SEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIE---DLK 856
Query: 3187 GRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAE 3246
G + A ++L + + +L + R A++ R + L AQ L + +
Sbjct: 857 GDEAKAKETLKKYEGEIR---QLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQ 913
Query: 3247 KLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKA 3291
+ + L ++ E+ QKE+LR+ EME + G + L E A
Sbjct: 914 EQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMA 958
Score = 34.7 bits (78), Expect = 2.2
Identities = 68/347 (19%), Positives = 139/347 (40%), Gaps = 31/347 (8%)
Query: 2984 ELLSGYKKLLGEKRQELLAQA--NKLRTGLFKIDE-TREKVQVMSLELEDAKKKVAEFQK 3040
+LL G ++L + +E Q N L+ G D+ T+ KV ++ +++ K + A
Sbjct: 538 DLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAG-SA 596
Query: 3041 QCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQA-LADNAQKDLEEALPALEEAM 3099
Q + ++ EQ+ +T I V E++ Q L Q++++E + +
Sbjct: 597 QGNNQACNSTSEVKDLLEQKSKLT-----IEVAELQRQLQLEVKNQQNIKEERERMRANL 651
Query: 3100 RALESLNKKDIGEI--------KSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQN 3151
L S + + + E +S G +E + Q M ++ + + QL E +
Sbjct: 652 EELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMH 711
Query: 3152 FIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYR 3211
+D +++++ A+ D Q +I + L G L
Sbjct: 712 DELDSAKRSEDREKGALIEEL--LQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKE 769
Query: 3212 VVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLA----------- 3260
V M+ Q + AL E+ E+ + E L ++ A
Sbjct: 770 EVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQE 829
Query: 3261 QKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYL 3307
+ E+L+ +SEE+E ++ + + L G++A+ +ET++ E ++ L
Sbjct: 830 ENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 48.9 bits (115), Expect = 1e-04
Identities = 78/361 (21%), Positives = 153/361 (42%), Gaps = 40/361 (11%)
Query: 2969 LELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLEL 3028
L R + + L+ + LL + Q+L A AN+ ++++ ++ V V ++
Sbjct: 623 LASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKI 682
Query: 3029 EDAKKKVA-EFQKQCEEYLVIIVQQKREADEQQKAVTANSE---KIAVEEI-KCQALADN 3083
++++ E + EE+ ++ Q K E QK T SE K VE++ KC D
Sbjct: 683 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE 742
Query: 3084 AQKDLEEALPA-------LEEAMRALESLNK---KDIGEIKSYGRPPAQVEIVMQAVMIL 3133
K +EE L EE + A+ + N K++ ++K+ +++ + +
Sbjct: 743 KLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802
Query: 3134 RGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLA- 3192
+ ++ +L E +K +K+ + ++I A + IG V L
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVA---NKEKTVQDLKQEIKALKEE-------IGNVQLEK 852
Query: 3193 AKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLK 3252
A+ L + + EL L + K +MN A L EK+ LA + L+++ E+ E LK
Sbjct: 853 AQQLSITSKVQELQNLL----KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 3253 KQYDE----------KLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEE 3302
E +Q EEL +E E +L+R ++ + + + +Q +++
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Query: 3303 D 3303
+
Sbjct: 969 E 969
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 48.9 bits (115), Expect = 1e-04
Identities = 78/361 (21%), Positives = 153/361 (42%), Gaps = 40/361 (11%)
Query: 2969 LELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLEL 3028
L R + + L+ + LL + Q+L A AN+ ++++ ++ V V ++
Sbjct: 623 LASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKI 682
Query: 3029 EDAKKKVA-EFQKQCEEYLVIIVQQKREADEQQKAVTANSE---KIAVEEI-KCQALADN 3083
++++ E + EE+ ++ Q K E QK T SE K VE++ KC D
Sbjct: 683 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE 742
Query: 3084 AQKDLEEALPA-------LEEAMRALESLNK---KDIGEIKSYGRPPAQVEIVMQAVMIL 3133
K +EE L EE + A+ + N K++ ++K+ +++ + +
Sbjct: 743 KLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802
Query: 3134 RGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLA- 3192
+ ++ +L E +K +K+ + ++I A + IG V L
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVA---NKEKTVQDLKQEIKALKEE-------IGNVQLEK 852
Query: 3193 AKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLK 3252
A+ L + + EL L + K +MN A L EK+ LA + L+++ E+ E LK
Sbjct: 853 AQQLSITSKVQELQNLL----KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 3253 KQYDE----------KLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEE 3302
E +Q EEL +E E +L+R ++ + + + +Q +++
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Query: 3303 D 3303
+
Sbjct: 969 E 969
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 48.9 bits (115), Expect = 1e-04
Identities = 78/361 (21%), Positives = 153/361 (42%), Gaps = 40/361 (11%)
Query: 2969 LELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLEL 3028
L R + + L+ + LL + Q+L A AN+ ++++ ++ V V ++
Sbjct: 623 LASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKI 682
Query: 3029 EDAKKKVA-EFQKQCEEYLVIIVQQKREADEQQKAVTANSE---KIAVEEI-KCQALADN 3083
++++ E + EE+ ++ Q K E QK T SE K VE++ KC D
Sbjct: 683 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE 742
Query: 3084 AQKDLEEALPA-------LEEAMRALESLNK---KDIGEIKSYGRPPAQVEIVMQAVMIL 3133
K +EE L EE + A+ + N K++ ++K+ +++ + +
Sbjct: 743 KLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKV 802
Query: 3134 RGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLA- 3192
+ ++ +L E +K +K+ + ++I A + IG V L
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVA---NKEKTVQDLKQEIKALKEE-------IGNVQLEK 852
Query: 3193 AKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLK 3252
A+ L + + EL L + K +MN A L EK+ LA + L+++ E+ E LK
Sbjct: 853 AQQLSITSKVQELQNLL----KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 3253 KQYDE----------KLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEE 3302
E +Q EEL +E E +L+R ++ + + + +Q +++
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Query: 3303 D 3303
+
Sbjct: 969 E 969
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 161,666,318
Number of Sequences: 37866
Number of extensions: 7159889
Number of successful extensions: 28231
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 324
Number of HSP's that attempted gapping in prelim test: 22893
Number of HSP's gapped (non-prelim): 4368
length of query: 4427
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4304
effective length of database: 13,590,000
effective search space: 58491360000
effective search space used: 58491360000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.