Guide to the Human Genome
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Search of human proteins with 74271834

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo
sapiens]
         (870 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens]  1738   0.0  
gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo sapi...  1738   0.0  
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R...    60   1e-08
gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]           59   2e-08
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]           59   2e-08
gi|189571664 DEP domain containing 6 [Homo sapiens]                    57   6e-08
gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isof...    54   6e-07
gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isof...    54   6e-07
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho...    49   3e-05
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom...    49   3e-05
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho...    49   3e-05
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom...    49   3e-05
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]              46   1e-04
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    46   2e-04
gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III i...    46   2e-04
gi|34734079 frizzled 6 [Homo sapiens]                                  42   0.003
gi|8393378 frizzled 3 [Homo sapiens]                                   42   0.003
gi|4503835 frizzled 9 [Homo sapiens]                                   39   0.021
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    39   0.027
gi|238859647 G protein-coupled receptor 128 [Homo sapiens]             38   0.047
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]    38   0.047
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]    38   0.047
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]    38   0.047
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]    38   0.047
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]                37   0.079
gi|41406097 dishevelled 3 [Homo sapiens]                               36   0.14 
gi|40807489 egf-like module containing, mucin-like, hormone rece...    36   0.14 
gi|6005762 frizzled 10 [Homo sapiens]                                  36   0.18 
gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]             35   0.39 
gi|4503825 frizzled 1 [Homo sapiens]                                   34   0.52 

>gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens]
          Length = 870

 Score = 1738 bits (4500), Expect = 0.0
 Identities = 870/870 (100%), Positives = 870/870 (100%)

Query: 1   MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAG 60
           MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAG
Sbjct: 1   MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAG 60

Query: 61  RANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVL 120
           RANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVL
Sbjct: 61  RANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVL 120

Query: 121 TLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMML 180
           TLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMML
Sbjct: 121 TLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMML 180

Query: 181 NPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVY 240
           NPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVY
Sbjct: 181 NPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVY 240

Query: 241 VENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVEL 300
           VENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVEL
Sbjct: 241 VENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVEL 300

Query: 301 LDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYV 360
           LDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYV
Sbjct: 301 LDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYV 360

Query: 361 SAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLI 420
           SAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLI
Sbjct: 361 SAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLI 420

Query: 421 AQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP 480
           AQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP
Sbjct: 421 AQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP 480

Query: 481 VGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLM 540
           VGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLM
Sbjct: 481 VGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLM 540

Query: 541 CMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNG 600
           CMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNG
Sbjct: 541 CMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNG 600

Query: 601 ELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVL 660
           ELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVL
Sbjct: 601 ELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVL 660

Query: 661 LCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIIL 720
           LCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIIL
Sbjct: 661 LCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIIL 720

Query: 721 PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGT 780
           PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGT
Sbjct: 721 PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGT 780

Query: 781 FCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQ 840
           FCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQ
Sbjct: 781 FCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQ 840

Query: 841 SPPAINANTLQQERYKEIEHSSPPSHSPKT 870
           SPPAINANTLQQERYKEIEHSSPPSHSPKT
Sbjct: 841 SPPAINANTLQQERYKEIEHSSPPSHSPKT 870


>gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo
           sapiens]
          Length = 870

 Score = 1738 bits (4500), Expect = 0.0
 Identities = 870/870 (100%), Positives = 870/870 (100%)

Query: 1   MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAG 60
           MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAG
Sbjct: 1   MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAG 60

Query: 61  RANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVL 120
           RANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVL
Sbjct: 61  RANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVL 120

Query: 121 TLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMML 180
           TLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMML
Sbjct: 121 TLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMML 180

Query: 181 NPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVY 240
           NPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVY
Sbjct: 181 NPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVY 240

Query: 241 VENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVEL 300
           VENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVEL
Sbjct: 241 VENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVEL 300

Query: 301 LDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYV 360
           LDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYV
Sbjct: 301 LDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYV 360

Query: 361 SAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLI 420
           SAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLI
Sbjct: 361 SAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLI 420

Query: 421 AQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP 480
           AQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP
Sbjct: 421 AQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP 480

Query: 481 VGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLM 540
           VGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLM
Sbjct: 481 VGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLM 540

Query: 541 CMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNG 600
           CMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNG
Sbjct: 541 CMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNG 600

Query: 601 ELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVL 660
           ELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVL
Sbjct: 601 ELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVL 660

Query: 661 LCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIIL 720
           LCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIIL
Sbjct: 661 LCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIIL 720

Query: 721 PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGT 780
           PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGT
Sbjct: 721 PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGT 780

Query: 781 FCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQ 840
           FCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQ
Sbjct: 781 FCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQ 840

Query: 841 SPPAINANTLQQERYKEIEHSSPPSHSPKT 870
           SPPAINANTLQQERYKEIEHSSPPSHSPKT
Sbjct: 841 SPPAINANTLQQERYKEIEHSSPPSHSPKT 870


>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
           exchange factor 1 [Homo sapiens]
          Length = 1659

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 25/69 (36%), Positives = 44/69 (63%)

Query: 765 NIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEF 824
           N++K+RR    T    F G + V+WL+E+G  S   E V  G  L++ G+I H++++++F
Sbjct: 426 NLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQF 485

Query: 825 RDEYLFYRF 833
           ++E + YRF
Sbjct: 486 KNEQVMYRF 494



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 766 IVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFR 825
           ++K+R    KT      G  LV WL+  G    R EAV  G  L   G + H+  + EFR
Sbjct: 528 VIKDRDYHLKTYKSVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFR 587

Query: 826 DEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEH 860
           DE  ++RF   + E+     + N   +  +K +E+
Sbjct: 588 DESQYFRF--HADEEMEGTSSKNKQLRNDFKLVEN 620


>gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]
          Length = 979

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 10/86 (11%)

Query: 748 KMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGD 807
           KM C+Q           N++K+R+    T    F G + VSWL+E+G      E V  G 
Sbjct: 387 KMMCRQ----------GNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQ 436

Query: 808 RLVQGGVIQHITNEYEFRDEYLFYRF 833
            L++ G+I H+T++++F+ E + YRF
Sbjct: 437 ALLENGIIHHVTDKHQFKPEQMLYRF 462



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 766 IVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFR 825
           +++++    +T         L+ WLI  G    R EA+I+G  L   G + H+  + EF+
Sbjct: 496 VIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSEFK 555

Query: 826 DEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEH 860
           DE L +RF   S E+   +   + L +   K +E+
Sbjct: 556 DEPLLFRFF--SDEEMEGSNMKHRLMKHDLKVVEN 588


>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
          Length = 1606

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 10/86 (11%)

Query: 748 KMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGD 807
           KM C+Q           N++K+R+    T    F G + VSWL+E+G      E V  G 
Sbjct: 387 KMMCRQ----------GNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQ 436

Query: 808 RLVQGGVIQHITNEYEFRDEYLFYRF 833
            L++ G+I H+T++++F+ E + YRF
Sbjct: 437 ALLENGIIHHVTDKHQFKPEQMLYRF 462



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 766 IVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFR 825
           +++++    +T         L+ WLI  G    R EA+I+G  L   G + H+  + EF+
Sbjct: 496 VIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSEFK 555

Query: 826 DEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEH 860
           DE L +RF   S E+   +   + L +   K +E+
Sbjct: 556 DEPLLFRFF--SDEEMEGSNMKHRLMKHDLKVVEN 588


>gi|189571664 DEP domain containing 6 [Homo sapiens]
          Length = 409

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 35/100 (35%), Positives = 54/100 (54%), Gaps = 6/100 (6%)

Query: 736 AENRDSPVSEEIKMTCQQF-IHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVG 794
           A+ R+     E+ +T +Q  +  H +     ++K+RR   KT    F   +L+ WLIE  
Sbjct: 22  AQQRELERMAEVLVTGEQLRLRLHEE----KVIKDRRHHLKTYPNCFVAKELIDWLIEHK 77

Query: 795 LASDRGEAVIYGDRLVQGGVIQHITNEY-EFRDEYLFYRF 833
            ASDR  A+    +L   G+I H+ +E+ EF+D  LFYRF
Sbjct: 78  EASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRF 117



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 21/54 (38%), Positives = 34/54 (62%)

Query: 780 TFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRF 833
           TF   + + WL++ G A+ R EA     RL++ G+IQH++N++ F D  L Y+F
Sbjct: 164 TFMASEFLDWLVQEGEATTRKEAEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQF 217


>gi|155030206 Rap guanine nucleotide exchange factor (GEF) 4 isoform
           b [Homo sapiens]
          Length = 867

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 26/79 (32%), Positives = 45/79 (56%), Gaps = 1/79 (1%)

Query: 765 NIVKERRCGAKTSAGTFCGCDLVSWLIE-VGLASDRGEAVIYGDRLVQGGVIQHITNEYE 823
           +++++R+   KT      G +LV W+++       R +AV     L++ GV+ H+  E+ 
Sbjct: 76  HMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHH 135

Query: 824 FRDEYLFYRFLQKSPEQSP 842
           F+D+YLFYRFL    E +P
Sbjct: 136 FQDKYLFYRFLDDEHEDAP 154


>gi|155030204 Rap guanine nucleotide exchange factor (GEF) 4 isoform
           a [Homo sapiens]
          Length = 1011

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 26/79 (32%), Positives = 45/79 (56%), Gaps = 1/79 (1%)

Query: 765 NIVKERRCGAKTSAGTFCGCDLVSWLIE-VGLASDRGEAVIYGDRLVQGGVIQHITNEYE 823
           +++++R+   KT      G +LV W+++       R +AV     L++ GV+ H+  E+ 
Sbjct: 220 HMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHH 279

Query: 824 FRDEYLFYRFLQKSPEQSP 842
           F+D+YLFYRFL    E +P
Sbjct: 280 FQDKYLFYRFLDDEHEDAP 298


>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
            sapiens]
          Length = 1221

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%)

Query: 392  ISLIWSLAILLLSKKYKQL----PHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQ-ILV 446
            IS I+S A LL    +++L    P  +  NL  A   +    ++  ++   N  G  I V
Sbjct: 874  ISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAV 933

Query: 447  FVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLLITG 503
             VLL+  L +T+ W GL AI +++ L K     I   I+   I GWG+PAL+V V+L   
Sbjct: 934  AVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSVVL--A 991

Query: 504  KHNGDSIDSAFFYGKEQ 520
              N + +     YGKE+
Sbjct: 992  SRNNNEVYGKESYGKEK 1008


>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
            sapiens]
          Length = 1250

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%)

Query: 392  ISLIWSLAILLLSKKYKQL----PHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQ-ILV 446
            IS I+S A LL    +++L    P  +  NL  A   +    ++  ++   N  G  I V
Sbjct: 874  ISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAV 933

Query: 447  FVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLLITG 503
             VLL+  L +T+ W GL AI +++ L K     I   I+   I GWG+PAL+V V+L   
Sbjct: 934  AVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSVVL--A 991

Query: 504  KHNGDSIDSAFFYGKEQ 520
              N + +     YGKE+
Sbjct: 992  SRNNNEVYGKESYGKEK 1008


>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
           sapiens]
          Length = 1193

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%)

Query: 392 ISLIWSLAILLLSKKYKQL----PHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQ-ILV 446
           IS I+S A LL    +++L    P  +  NL  A   +    ++  ++   N  G  I V
Sbjct: 846 ISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAV 905

Query: 447 FVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLLITG 503
            VLL+  L +T+ W GL AI +++ L K     I   I+   I GWG+PAL+V V+L   
Sbjct: 906 AVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSVVL--A 963

Query: 504 KHNGDSIDSAFFYGKEQ 520
             N + +     YGKE+
Sbjct: 964 SRNNNEVYGKESYGKEK 980


>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
           sapiens]
          Length = 1222

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 10/137 (7%)

Query: 392 ISLIWSLAILLLSKKYKQL----PHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQ-ILV 446
           IS I+S A LL    +++L    P  +  NL  A   +    ++  ++   N  G  I V
Sbjct: 846 ISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAV 905

Query: 447 FVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLLITG 503
            VLL+  L +T+ W GL AI +++ L K     I   I+   I GWG+PAL+V V+L   
Sbjct: 906 AVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSVVL--A 963

Query: 504 KHNGDSIDSAFFYGKEQ 520
             N + +     YGKE+
Sbjct: 964 SRNNNEVYGKESYGKEK 980


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 11/163 (6%)

Query: 387  SIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQ-IL 445
            SI   ++++  +A   L K Y   P  +  NL  A  ++    +I +++     VG  I 
Sbjct: 2755 SIFLGVAVVTYIAFHKLRKDY---PAKILINLCTALLMLNLVFLINSWLSSFQKVGVCIT 2811

Query: 446  VFVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLLIT 502
              V L+  L  ++ W GL A+ ++L L K   + IP  I+   + GWGIPA++V + +  
Sbjct: 2812 AAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSV 2871

Query: 503  GK--HNGDSIDSAFFYGKEQMI--TTAVTLFCSILIAGISLMC 541
             K  +   S  + F + K+  I   + V  FC I +  +S+ C
Sbjct: 2872 KKDLYGTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFC 2914


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
           isoform 2 [Homo sapiens]
          Length = 2098

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 6/99 (6%)

Query: 768 KERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYE-FRD 826
           ++ R   +T      G +LV+WLI  G  + R +A+  G  +V G  +  +++  + FRD
Sbjct: 372 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 431

Query: 827 EYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPS 865
           EY  YR LQ +     P+ +++++       +E  S PS
Sbjct: 432 EYALYRPLQSTEFSETPSPDSDSV-----NSVEGHSEPS 465


>gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III
           isoform 3 [Homo sapiens]
          Length = 451

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 6/99 (6%)

Query: 768 KERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYE-FRD 826
           ++ R   +T      G +LV+WLI  G  + R +A+  G  +V G  +  +++  + FRD
Sbjct: 275 QDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRD 334

Query: 827 EYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPS 865
           EY  YR LQ +     P+ +++++       +E  S PS
Sbjct: 335 EYALYRPLQSTEFSETPSPDSDSV-----NSVEGHSEPS 368


>gi|34734079 frizzled 6 [Homo sapiens]
          Length = 706

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 52/225 (23%), Positives = 90/225 (40%), Gaps = 39/225 (17%)

Query: 357 IMYVSAWLLTFPT--MDPKPLAYAIQNVSFDISIVSLISLIWSLAILL----LSKKYKQL 410
           I  + A L TF T  +D +   Y  + + +     S++SL++ +  LL       K  + 
Sbjct: 207 IFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEK 266

Query: 411 PHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFL 470
             +  T +L +Q+  C                  ++F+LLY    +  +W  +L I+ FL
Sbjct: 267 LELGDTVVLGSQNKACT-----------------VLFMLLYFFTMAGTVWWVILTITWFL 309

Query: 471 LKKR----ERVQIPVGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQM----- 521
              R    E ++          WG P  L  +LL   K  GD+I    F G   +     
Sbjct: 310 AAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRY 369

Query: 522 -----ITTAVTLFCSILIAGISLMCMNQTAQAGSYEGFDQSQSHK 561
                +   V +  S+L+AGI  + +N   Q   ++G +Q +  K
Sbjct: 370 FVLLPLCLCVFVGLSLLLAGI--ISLNHVRQVIQHDGRNQEKLKK 412


>gi|8393378 frizzled 3 [Homo sapiens]
          Length = 666

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/193 (22%), Positives = 78/193 (40%), Gaps = 22/193 (11%)

Query: 357 IMYVSAWLLTFPT--MDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHML 414
           I+ +SA L TF T  +D     Y  + + F      ++SLI+ +  LL  +         
Sbjct: 211 IICLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDR--------- 261

Query: 415 TTNLLIAQSIVCAGMMIWNFVKEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKK- 473
               +   + + A        +  +     ++F++LY    +  +W  +L I+ FL    
Sbjct: 262 ----VACNASIPAQYKASTVTQGSHNKACTMLFMILYFFTMAGSVWWVILTITWFLAAVP 317

Query: 474 ---RERVQIPVGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFF---YGKEQMITTAVT 527
               E ++    +   S WGIP  L  +LL   K  GD+I    F   Y  + +    + 
Sbjct: 318 KWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLA 377

Query: 528 LFCSILIAGISLM 540
             C  ++ G+SL+
Sbjct: 378 PLCLYVVVGVSLL 390


>gi|4503835 frizzled 9 [Homo sapiens]
          Length = 591

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 47/216 (21%), Positives = 93/216 (43%), Gaps = 30/216 (13%)

Query: 327 PGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDI 386
           PGV +F ++ + +  ++   +      SA   + +A+ +    ++P    Y  + + F  
Sbjct: 217 PGVEVFWSRRDKDFALVWMAVW-----SALCFFSTAFTVLTFLLEPHRFQYPERPIIF-- 269

Query: 387 SIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNF--VGQI 444
             +S+   ++SLA L+ +             +  AQS+ C       +V ++     G  
Sbjct: 270 --LSMCYNVYSLAFLIRA-------------VAGAQSVACDQEAGALYVIQEGLENTGCT 314

Query: 445 LVFVLLYSSLYSTYLWTGLLAISLFLLKKR----ERVQIPVGIIIISGWGIPALLVGVLL 500
           LVF+LLY    ++ LW  +L ++ FL   +    E ++       ++ WG+PAL   V+L
Sbjct: 315 LVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVIL 374

Query: 501 ITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAG 536
              K  GD +    +         A+T F  + ++G
Sbjct: 375 TLRKVAGDELTGLCYVASTD--AAALTGFVLVPLSG 408


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 38.5 bits (88), Expect = 0.027
 Identities = 32/122 (26%), Positives = 58/122 (47%), Gaps = 10/122 (8%)

Query: 386  ISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFV-------KEK 438
            + IV+  ++  SLA LL++     L  ML +NL      +   + +   V        E 
Sbjct: 2468 LKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQTEN 2527

Query: 439  NFVGQILVFVLLYSSLYSTYLWTGLLAISLF--LLKKRERVQIPVGIIIISGWGIPALLV 496
             F+  + V +LL+    ST+ WT + ++ ++  L + R     P+    + GWGIPA++ 
Sbjct: 2528 PFLCTV-VAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVGWGIPAIVT 2586

Query: 497  GV 498
            G+
Sbjct: 2587 GL 2588


>gi|238859647 G protein-coupled receptor 128 [Homo sapiens]
          Length = 797

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 446 VFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIPVGIII---ISGWGIPALLVGVLL-I 501
           +  LL+  L  T+ W  L A  L+ L  R    +P   I+   + GWG+PA++V + + +
Sbjct: 529 IAALLHYFLLVTFTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGV 588

Query: 502 TGKHNGDSIDSAFFYGKEQMITTAV 526
               NG++      Y +E++   A+
Sbjct: 589 IYSQNGNNPQWELDYRQEKICWLAI 613


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 14/110 (12%)

Query: 444 ILVFVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLL 500
           I V V L+  L  ++ W GL A  ++L L K     I   I+   I GWG+PA++V ++L
Sbjct: 673 ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 732

Query: 501 IT----------GKH-NGDSIDSAFFYGKEQMITTAVTLFCSILIAGISL 539
                       GK  NG   D  +         T V  FC I +  +S+
Sbjct: 733 TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSM 782


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 14/110 (12%)

Query: 444 ILVFVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLL 500
           I V V L+  L  ++ W GL A  ++L L K     I   I+   I GWG+PA++V ++L
Sbjct: 681 ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 740

Query: 501 IT----------GKH-NGDSIDSAFFYGKEQMITTAVTLFCSILIAGISL 539
                       GK  NG   D  +         T V  FC I +  +S+
Sbjct: 741 TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSM 790


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 14/110 (12%)

Query: 444 ILVFVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLL 500
           I V V L+  L  ++ W GL A  ++L L K     I   I+   I GWG+PA++V ++L
Sbjct: 695 ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 754

Query: 501 IT----------GKH-NGDSIDSAFFYGKEQMITTAVTLFCSILIAGISL 539
                       GK  NG   D  +         T V  FC I +  +S+
Sbjct: 755 TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSM 804


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 14/110 (12%)

Query: 444 ILVFVLLYSSLYSTYLWTGLLAISLFL-LKKRERVQIPVGII--IISGWGIPALLVGVLL 500
           I V V L+  L  ++ W GL A  ++L L K     I   I+   I GWG+PA++V ++L
Sbjct: 692 ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 751

Query: 501 IT----------GKH-NGDSIDSAFFYGKEQMITTAVTLFCSILIAGISL 539
                       GK  NG   D  +         T V  FC I +  +S+
Sbjct: 752 TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSM 801


>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
          Length = 895

 Score = 37.0 bits (84), Expect = 0.079
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 3/88 (3%)

Query: 574 PAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRC 633
           P P+  P L     P        +G    H P++ P       EPV  S E+    +   
Sbjct: 94  PPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEER---LKLA 150

Query: 634 NSQSCILAQEEEQYLQSGDQQLTRHVLL 661
             Q+ +L Q+EE+  Q GD  L  H LL
Sbjct: 151 QQQAALLMQQEERAKQQGDHSLKEHELL 178


>gi|41406097 dishevelled 3 [Homo sapiens]
          Length = 716

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 767 VKERRCGAKTSAGTFCGCDLVSWLIE-VGLASDRGEAVIYGDRLVQGGVIQHITNEYEFR 825
           V++R     T    F G D+V WL   V   +DR EA  Y   L++ G I+H  N+  F 
Sbjct: 428 VRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFS 487

Query: 826 DE--YLF 830
           ++  Y+F
Sbjct: 488 EQCYYIF 494


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 13/128 (10%)

Query: 377 YAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHM-LTTNLLIAQSIVCAGMMIWNFV 435
           Y I +V   IS+V L+  I +  +    + +    H+ L   LL+A+++  AG+      
Sbjct: 603 YIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIH----- 657

Query: 436 KEKNFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERV-------QIPVGIIIISG 488
           K  N +G  ++   L+    + + W  + A+ LFL+ +  +V        I +  I   G
Sbjct: 658 KTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFG 717

Query: 489 WGIPALLV 496
           +G+P L+V
Sbjct: 718 YGLPMLVV 725


>gi|6005762 frizzled 10 [Homo sapiens]
          Length = 581

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 6/98 (6%)

Query: 442 GQILVFVLLYSSLYSTYLWTGLLAISLFLLKKR----ERVQIPVGIIIISGWGIPALLVG 497
           G  LVF++LY    ++ LW  +L ++ FL   +    E ++       ++ W IPA+   
Sbjct: 308 GCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTI 367

Query: 498 VLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIA 535
           ++L+  +  GD +    + G   M   A+T F  I +A
Sbjct: 368 LILVMRRVAGDELTGVCYVG--SMDVNALTGFVLIPLA 403


>gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]
          Length = 1512

 Score = 34.7 bits (78), Expect = 0.39
 Identities = 28/110 (25%), Positives = 43/110 (39%), Gaps = 13/110 (11%)

Query: 721  PFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGT 780
            PF R  EFLW    +A       +EE+      +   + +L    +VK    G KT    
Sbjct: 1160 PFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVK----GRKTEKEK 1215

Query: 781  FCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLF 830
            F G D  +  IE  +++          R +QGG   H+   +    E +F
Sbjct: 1216 FAGGDYTT-TIEAFISA--------SGRAIQGGTSHHLGQNFSKMFEIVF 1256


>gi|4503825 frizzled 1 [Homo sapiens]
          Length = 647

 Score = 34.3 bits (77), Expect = 0.52
 Identities = 18/80 (22%), Positives = 39/80 (48%), Gaps = 4/80 (5%)

Query: 442 GQILVFVLLYSSLYSTYLWTGLLAISLFLLKK----RERVQIPVGIIIISGWGIPALLVG 497
           G  ++F++LY    ++ +W  +L+++ FL        E ++       ++ W +PA+   
Sbjct: 401 GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTI 460

Query: 498 VLLITGKHNGDSIDSAFFYG 517
            +L  G+ +GD +    F G
Sbjct: 461 TILALGQVDGDVLSGVCFVG 480


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,287,344
Number of Sequences: 37866
Number of extensions: 1359773
Number of successful extensions: 4183
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 4117
Number of HSP's gapped (non-prelim): 90
length of query: 870
length of database: 18,247,518
effective HSP length: 111
effective length of query: 759
effective length of database: 14,044,392
effective search space: 10659693528
effective search space used: 10659693528
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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