Search of human proteins with 74229015

Search of human proteins with 74229015

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo
sapiens]
         (414 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo sa...   862   0.0  
gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo sa...   720   0.0  
gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo sa...   720   0.0  
gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens]           389   e-108
gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo sa...   378   e-105
gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo sa...   368   e-102
gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo...   240   1e-63
gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo...   131   1e-30
gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo sa...    73   4e-13
gi|24234747 interleukin enhancer binding factor 2 [Homo sapiens]       31   1.8  
gi|7662386 NLR family, pyrin domain containing 1 isoform 2 [Homo...    29   9.0  
gi|14719835 NLR family, pyrin domain containing 1 isoform 4 [Hom...    29   9.0  
gi|14719833 NLR family, pyrin domain containing 1 isoform 3 [Hom...    29   9.0  
gi|14719829 NLR family, pyrin domain containing 1 isoform 1 [Hom...    29   9.0  
gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]        29   9.0  
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]        29   9.0  
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]          29   9.0  
gi|62750354 matrin 3 [Homo sapiens]                                    29   9.0  
gi|21626466 matrin 3 [Homo sapiens]                                    29   9.0  

>gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo
           sapiens]
          Length = 414

 Score =  862 bits (2227), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK 60
           MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK
Sbjct: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK 60

Query: 61  GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE 120
           GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE
Sbjct: 61  GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE 120

Query: 121 VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL 180
           VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL
Sbjct: 121 VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL 180

Query: 181 QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW 240
           QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW
Sbjct: 181 QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW 240

Query: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
           ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300

Query: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQHTPGSIHPTGRR 360
           PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQHTPGSIHPTGRR
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQHTPGSIHPTGRR 360

Query: 361 GLDLHHPLNASASWGKGLQCYLDQFLHFQVGLLIQRGQSSSVSWCIIQDRTQVS 414
           GLDLHHPLNASASWGKGLQCYLDQFLHFQVGLLIQRGQSSSVSWCIIQDRTQVS
Sbjct: 361 GLDLHHPLNASASWGKGLQCYLDQFLHFQVGLLIQRGQSSSVSWCIIQDRTQVS 414


>gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo
           sapiens]
          Length = 364

 Score =  720 bits (1859), Expect = 0.0
 Identities = 347/354 (98%), Positives = 349/354 (98%)

Query: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK 60
           MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK
Sbjct: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK 60

Query: 61  GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE 120
           GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE
Sbjct: 61  GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE 120

Query: 121 VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL 180
           VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL
Sbjct: 121 VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL 180

Query: 181 QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW 240
           QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW
Sbjct: 181 QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW 240

Query: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
           ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300

Query: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQHTPGSI 354
           PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILL +    S+
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRPPASSL 354


>gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo
           sapiens]
          Length = 400

 Score =  720 bits (1858), Expect = 0.0
 Identities = 346/348 (99%), Positives = 347/348 (99%)

Query: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK 60
           MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK
Sbjct: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVK 60

Query: 61  GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE 120
           GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE
Sbjct: 61  GGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFE 120

Query: 121 VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL 180
           VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL
Sbjct: 121 VQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDL 180

Query: 181 QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW 240
           QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW
Sbjct: 181 QKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAW 240

Query: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
           ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300

Query: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQ 348
           PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILL +
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLAE 348


>gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens]
          Length = 1087

 Score =  389 bits (999), Expect = e-108
 Identities = 206/344 (59%), Positives = 243/344 (70%), Gaps = 13/344 (3%)

Query: 4    LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
            L  TPA  LDKFI ++L P+  F  Q+N A+D IC FLKE CFR S  P+ V KVVKGGS
Sbjct: 747  LYQTPAGDLDKFISEFLQPNRQFLAQVNKAVDTICSFLKENCFRNS--PIKVIKVVKGGS 804

Query: 64   SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
            S KGT LRGRSDADLVVFLS  + F +Q N+R E I EIR QLEACQ+ER F VKFEV  
Sbjct: 805  SAKGTALRGRSDADLVVFLSCFSQFTEQGNKRAEIISEIRAQLEACQQERQFEVKFEVS- 863

Query: 124  PRWGNPRALSFVLSS-LQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQK 182
             +W NPR LSF L+S   L + V+FDVLPAFDALGQL  G +P+ Q+YV LI   ++   
Sbjct: 864  -KWENPRVLSFSLTSQTMLDQSVDFDVLPAFDALGQLVSGSRPSSQVYVDLIHSYSNA-- 920

Query: 183  EGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNC---KKKLGKLPPQYALELLTVYA 239
             GE+STCFTELQRDF+  RPTKLKSLIRLVKHWYQ C    K  G LPPQ+ LELLTVYA
Sbjct: 921  -GEYSTCFTELQRDFIISRPTKLKSLIRLVKHWYQQCTKISKGRGSLPPQHGLELLTVYA 979

Query: 240  WERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVIL 299
            WE+G   + FN A+GFRTVLELV  Y+QLCIYWT  Y+ K+  +  +L++QL KPRP+IL
Sbjct: 980  WEQGGKDSQFNMAEGFRTVLELVTQYRQLCIYWTINYNAKDKTVGDFLKQQLQKPRPIIL 1039

Query: 300  DPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343
            DPADPTGNLG      W  LA+EA A  +  C    +G P+  W
Sbjct: 1040 DPADPTGNLGHN--ARWDLLAKEAAACTSALCCMGRNGIPIQPW 1081



 Score =  295 bits (756), Expect = 4e-80
 Identities = 169/369 (45%), Positives = 224/369 (60%), Gaps = 25/369 (6%)

Query: 2   MDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKG 61
           +DL   P K LD+FI+D+L P   F+ Q+  AIDII   L E C   +S      +V KG
Sbjct: 406 LDLSQIPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHENCVHKAS------RVSKG 459

Query: 62  GSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEV 121
           GS G+GT LR   D +L++FL+  T ++DQ  RR E + E+R QLE+  +++  S+   +
Sbjct: 460 GSFGRGTDLRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLESWWQDQVPSLS--L 517

Query: 122 QAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQ 181
           Q P    P AL F L S  L    +  +LPAFDA+GQL+ G KPNPQ+Y +L+   T   
Sbjct: 518 QFPEQNVPEALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLL---TSGC 574

Query: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWY-QNCKKKLGK------LPPQYALEL 234
           +EGE   CF EL+R+F+  RP KLK+LI LVKHWY Q   +  GK      LPP YALEL
Sbjct: 575 QEGEHKACFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALEL 634

Query: 235 LTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKP 294
           LT++AWE+G  +  FN AQGFRTVL LV  +QQLC+YWT  Y  ++P +  +L  QL KP
Sbjct: 635 LTIFAWEQGCRQDCFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKP 694

Query: 295 RPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQHTPGSI 354
           RP++LDPADPT N+G G    W  LAQEA A     CF + DG+ V  W ++    P  +
Sbjct: 695 RPLVLDPADPTWNVGHG---SWELLAQEAAALGMQACFLSRDGTSVQPWDVM----PALL 747

Query: 355 HPTGRRGLD 363
           + T    LD
Sbjct: 748 YQTPAGDLD 756



 Score =  283 bits (724), Expect = 2e-76
 Identities = 155/345 (44%), Positives = 214/345 (62%), Gaps = 8/345 (2%)

Query: 2   MDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKG 61
           MDL +TPA +LD+F+   L P   F  +   A+  +   L+ER  R  +    V K VKG
Sbjct: 1   MDLYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKG 60

Query: 62  GSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEV 121
           GSSG+GT L+G  D++LV+FL    ++ DQ  RR E + E+R  LE+  +     ++   
Sbjct: 61  GSSGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVPGLRLTF 120

Query: 122 QAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQ 181
             P    P AL F L+S+ L + ++  ++PAF+ LGQ   G KP PQ+Y  L+       
Sbjct: 121 --PEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNSGC--- 175

Query: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWY-QNCKKKLGK--LPPQYALELLTVY 238
           + GE + CFTEL+R+F+  RP KLK+LI LVKHWY Q C + L K  LPP YALELLT++
Sbjct: 176 QGGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPVYALELLTIF 235

Query: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298
           AWE+G  K  F+ A+G RTVL L+  +Q LC++WT  Y F++P + ++L+RQL +PRPVI
Sbjct: 236 AWEQGCKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRPRPVI 295

Query: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343
           LDPADPT +LG G    W  LAQEA +  ++PCF    G PV SW
Sbjct: 296 LDPADPTWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSW 340


>gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo
           sapiens]
          Length = 719

 Score =  378 bits (971), Expect = e-105
 Identities = 194/362 (53%), Positives = 255/362 (70%), Gaps = 13/362 (3%)

Query: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
           L  TP   LDKFI+++L P+ CF  QI+ A++II  FLKE CFR S+  +   ++V+GGS
Sbjct: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396

Query: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
           + KGT L+  SDADLVVF + L ++  Q N R + ++EI  QL+A  RE+   ++   + 
Sbjct: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456

Query: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181
           P+W  PR LSF L S  L E V FDVLPAF+ALGQL+ G  P+P++Y  LI+  + +DL 
Sbjct: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516

Query: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238
             GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL   G LPP+YALELLT+Y
Sbjct: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575

Query: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298
           AWE+GS    F+TA+GFRTVLELV  YQQLCI+W   Y+F++  + K+L  QL K RPVI
Sbjct: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635

Query: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQHTPGS----I 354
           LDPA+PTG++GGGD   W  LA+EA+ WL+ PCFK+  G+P+  W + T  TPGS    I
Sbjct: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARI 695

Query: 355 HP 356
           HP
Sbjct: 696 HP 697



 Score =  230 bits (586), Expect = 2e-60
 Identities = 144/357 (40%), Positives = 194/357 (54%), Gaps = 23/357 (6%)

Query: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
           L + PA+ L  FI++YL P    +  I+  ++ IC  L+E       +P+ V  V  GGS
Sbjct: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62

Query: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
            G+ T LRG SD  LV+F S L  FQDQ   + + + +   +L+ C   +     FE+Q 
Sbjct: 63  YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122

Query: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183
              G      F +      + + F+VL AF+AL        P+P IY +L          
Sbjct: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173

Query: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240
            GEF+ CFTELQ+ F   RP KLK LI L+KHW+Q C+KK+  LP    YALELLTVYAW
Sbjct: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233

Query: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
           E+G  K +F+ A+G RTVLEL+   ++LCIYW   Y+F++  I   L  QL   RPVILD
Sbjct: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293

Query: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQ---HTPGSI 354
           P DPT N+  GD   W+ L +EA+ WL  P   N    P  SW +L      TPG +
Sbjct: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVLPAPLFTTPGHL 347


>gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo
           sapiens]
          Length = 687

 Score =  368 bits (945), Expect = e-102
 Identities = 186/345 (53%), Positives = 246/345 (71%), Gaps = 9/345 (2%)

Query: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
           L  TP   LDKFI+++L P+ CF  QI+ A++II  FLKE CFR S+  +   ++V+GGS
Sbjct: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396

Query: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
           + KGT L+  SDADLVVF + L ++  Q N R + ++EI  QL+A  RE+   ++   + 
Sbjct: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456

Query: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181
           P+W  PR LSF L S  L E V FDVLPAF+ALGQL+ G  P+P++Y  LI+  + +DL 
Sbjct: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516

Query: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238
             GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL   G LPP+YALELLT+Y
Sbjct: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575

Query: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298
           AWE+GS    F+TA+GFRTVLELV  YQQLCI+W   Y+F++  + K+L  QL K RPVI
Sbjct: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635

Query: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343
           LDPA+PTG++GGGD   W  LA+EA+ WL+ PCFK+  G+P+  W
Sbjct: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPW 680



 Score =  230 bits (586), Expect = 2e-60
 Identities = 144/357 (40%), Positives = 194/357 (54%), Gaps = 23/357 (6%)

Query: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
           L + PA+ L  FI++YL P    +  I+  ++ IC  L+E       +P+ V  V  GGS
Sbjct: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62

Query: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
            G+ T LRG SD  LV+F S L  FQDQ   + + + +   +L+ C   +     FE+Q 
Sbjct: 63  YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122

Query: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183
              G      F +      + + F+VL AF+AL        P+P IY +L          
Sbjct: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173

Query: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240
            GEF+ CFTELQ+ F   RP KLK LI L+KHW+Q C+KK+  LP    YALELLTVYAW
Sbjct: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233

Query: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
           E+G  K +F+ A+G RTVLEL+   ++LCIYW   Y+F++  I   L  QL   RPVILD
Sbjct: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293

Query: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQ---HTPGSI 354
           P DPT N+  GD   W+ L +EA+ WL  P   N    P  SW +L      TPG +
Sbjct: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVLPAPLFTTPGHL 347


>gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo
           sapiens]
          Length = 514

 Score =  240 bits (613), Expect = 1e-63
 Identities = 141/350 (40%), Positives = 198/350 (56%), Gaps = 14/350 (4%)

Query: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCF---RGSSYPVCVSK 57
           M +L +TPA  LD F+  +L P   ++ ++  A+  +  FL++  F   RG    V V K
Sbjct: 4   MQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLK 63

Query: 58  VVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSV 117
           VVK GS G GT LR   + +LV FLS   +FQ+      + ++ I + +   Q +    +
Sbjct: 64  VVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTM--WQSQDLLDL 121

Query: 118 KFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEEC 177
             E        P AL F + +    E +   ++PA+ ALG      +P P++YV LI+ C
Sbjct: 122 GLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKAC 181

Query: 178 TDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQN---CKKKLGKLPPQYALEL 234
                 G F   F+ELQR+F+K RPTKLKSL+RLVKHWYQ     +     LPP YALEL
Sbjct: 182 GG---PGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238

Query: 235 LTVYAWERGSMKT-HFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTK 293
           LT+YAWE G+ +  +F   +GF TV++L++ Y+ +CIYWTKYY   N IIE  +R+QL K
Sbjct: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298

Query: 294 PRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343
            RP+ILDPADPT N+  G    W  +AQ A   L   C  +   +P+SSW
Sbjct: 299 ERPIILDPADPTLNVAEG--YRWDIVAQRASQCLKQDCCYDNRENPISSW 346


>gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo
           sapiens]
          Length = 255

 Score =  131 bits (330), Expect = 1e-30
 Identities = 81/220 (36%), Positives = 118/220 (53%), Gaps = 8/220 (3%)

Query: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCF---RGSSYPVCVSK 57
           M +L +TPA  LD F+  +L P   ++ ++  A+  +  FL++  F   RG    V V K
Sbjct: 4   MQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLK 63

Query: 58  VVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSV 117
           VVK GS G GT LR   + +LV FLS   +FQ+      + ++ I + +   Q +    +
Sbjct: 64  VVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTM--WQSQDLLDL 121

Query: 118 KFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEEC 177
             E        P AL F + +    E +   ++PA+ ALG      +P P++YV LI+ C
Sbjct: 122 GLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKAC 181

Query: 178 TDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQ 217
                 G F   F+ELQR+F+K RPTKLKSL+RLVKHWYQ
Sbjct: 182 GG---PGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQ 218


>gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo
           sapiens]
          Length = 172

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 50/155 (32%), Positives = 77/155 (49%), Gaps = 11/155 (7%)

Query: 4   LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
           L + PA+ L  FI++YL P    +  I+  ++ IC  L+E       +P+ V  V  GGS
Sbjct: 8   LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62

Query: 64  SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
            G+ T LRG SD  LV+F S L  FQDQ   + + + +   +L+ C   +     FE+Q 
Sbjct: 63  YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122

Query: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQ 158
              G      F +      + + F+VL AF+AL +
Sbjct: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSK 151


>gi|24234747 interleukin enhancer binding factor 2 [Homo sapiens]
          Length = 390

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 22/86 (25%), Positives = 38/86 (44%)

Query: 20  LLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLV 79
           L P++  +  I   +  I   +        ++ V + +V + GS  KGT   G + ADLV
Sbjct: 64  LAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLV 123

Query: 80  VFLSPLTTFQDQLNRRGEFIQEIRRQ 105
           V L  L T +       + ++ +R Q
Sbjct: 124 VILKILPTLEAVAALGNKVVESLRAQ 149


>gi|7662386 NLR family, pyrin domain containing 1 isoform 2 [Homo
            sapiens]
          Length = 1429

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 9/50 (18%)

Query: 201  RPTKLKSLIRLVKHWYQNCK----KKLGKLPPQYALELLTVYAWERGSMK 246
            RP++++ L  L + W + CK    + L +  P   +EL     WE+GS K
Sbjct: 1378 RPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMEL-----WEKGSKK 1422


>gi|14719835 NLR family, pyrin domain containing 1 isoform 4 [Homo
            sapiens]
          Length = 1399

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 9/50 (18%)

Query: 201  RPTKLKSLIRLVKHWYQNCK----KKLGKLPPQYALELLTVYAWERGSMK 246
            RP++++ L  L + W + CK    + L +  P   +EL     WE+GS K
Sbjct: 1348 RPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMEL-----WEKGSKK 1392


>gi|14719833 NLR family, pyrin domain containing 1 isoform 3 [Homo
            sapiens]
          Length = 1443

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 9/50 (18%)

Query: 201  RPTKLKSLIRLVKHWYQNCK----KKLGKLPPQYALELLTVYAWERGSMK 246
            RP++++ L  L + W + CK    + L +  P   +EL     WE+GS K
Sbjct: 1392 RPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMEL-----WEKGSKK 1436


>gi|14719829 NLR family, pyrin domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 1473

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 9/50 (18%)

Query: 201  RPTKLKSLIRLVKHWYQNCK----KKLGKLPPQYALELLTVYAWERGSMK 246
            RP++++ L  L + W + CK    + L +  P   +EL     WE+GS K
Sbjct: 1422 RPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMEL-----WEKGSKK 1466


>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
          Length = 770

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 197 FLKQRPTKLKSLIRLVKHWYQ-NCKKKLGKLPPQYALEL 234
           F+  RP   K +++L++H Y   C K+  +L P + L++
Sbjct: 261 FINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKI 299


>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
          Length = 893

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 197 FLKQRPTKLKSLIRLVKHWYQ-NCKKKLGKLPPQYALEL 234
           F+  RP   K +++L++H Y   C K+  +L P + L++
Sbjct: 222 FINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKI 260


>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
          Length = 932

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 197 FLKQRPTKLKSLIRLVKHWYQ-NCKKKLGKLPPQYALEL 234
           F+  RP   K +++L++H Y   C K+  +L P + L++
Sbjct: 261 FINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKI 299


>gi|62750354 matrin 3 [Homo sapiens]
          Length = 847

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 248 HFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILDPADPTGN 307
           H N A   R    L+  Y +    W    D  + + + ++ +Q T P P IL P  P+ +
Sbjct: 309 HINGASHSRRCQLLLEIYPE----WNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFH 364

Query: 308 LGG 310
           LGG
Sbjct: 365 LGG 367


>gi|21626466 matrin 3 [Homo sapiens]
          Length = 847

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 248 HFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILDPADPTGN 307
           H N A   R    L+  Y +    W    D  + + + ++ +Q T P P IL P  P+ +
Sbjct: 309 HINGASHSRRCQLLLEIYPE----WNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFH 364

Query: 308 LGG 310
           LGG
Sbjct: 365 LGG 367


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,417,568
Number of Sequences: 37866
Number of extensions: 854772
Number of successful extensions: 1885
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1833
Number of HSP's gapped (non-prelim): 23
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.