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Search of human proteins with 73695881
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73695881 aldehyde dehydrogenase 3B2 [Homo sapiens]
(385 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73695881 aldehyde dehydrogenase 3B2 [Homo sapiens] 788 0.0
gi|73695879 aldehyde dehydrogenase 3B2 [Homo sapiens] 788 0.0
gi|238814371 aldehyde dehydrogenase 3B1 isoform a [Homo sapiens] 647 0.0
gi|4502043 aldehyde dehydrogenase 3B1 isoform a [Homo sapiens] 647 0.0
gi|71773324 aldehyde dehydrogenase 3B1 isoform b [Homo sapiens] 639 0.0
gi|4557303 aldehyde dehydrogenase 3A2 isoform 2 [Homo sapiens] 410 e-114
gi|73466520 aldehyde dehydrogenase 3A2 isoform 1 [Homo sapiens] 410 e-114
gi|22907049 aldehyde dehydrogenase 3A1 [Homo sapiens] 407 e-113
gi|206597441 aldehyde dehydrogenase 3A1 [Homo sapiens] 407 e-113
gi|206597439 aldehyde dehydrogenase 3A1 [Homo sapiens] 407 e-113
gi|153266822 aldehyde dehydrogenase 1A3 [Homo sapiens] 141 9e-34
gi|4507229 aldehyde dehydrogenase 5A1 isoform 2 precursor [Homo ... 135 8e-32
gi|25777721 aldehyde dehydrogenase 5A1 isoform 1 precursor [Homo... 134 2e-31
gi|25777732 mitochondrial aldehyde dehydrogenase 2 precursor [Ho... 129 6e-30
gi|115387104 aldehyde dehydrogenase 9A1 [Homo sapiens] 129 6e-30
gi|12007648 aldehyde dehydrogenase 8A1 isoform 1 [Homo sapiens] 127 1e-29
gi|25777728 aldehyde dehydrogenase 1A2 isoform 3 [Homo sapiens] 122 4e-28
gi|25777724 aldehyde dehydrogenase 1A2 isoform 1 [Homo sapiens] 122 4e-28
gi|238814322 aldehyde dehydrogenase 1 family, member L2 [Homo sa... 120 2e-27
gi|25777730 aldehyde dehydrogenase 1B1 precursor [Homo sapiens] 119 4e-27
gi|21361176 aldehyde dehydrogenase 1A1 [Homo sapiens] 119 5e-27
gi|21614513 aldehyde dehydrogenase 1 family, member L1 [Homo sap... 110 3e-24
gi|25952152 aldehyde dehydrogenase 8A1 isoform 2 [Homo sapiens] 109 4e-24
gi|25777726 aldehyde dehydrogenase 1A2 isoform 2 [Homo sapiens] 102 6e-22
gi|11095441 aldehyde dehydrogenase 6A1 precursor [Homo sapiens] 94 2e-19
gi|188035924 aldehyde dehydrogenase 7 family, member A1 [Homo sa... 75 1e-13
gi|25777736 aldehyde dehydrogenase 4A1 isoform a precursor [Homo... 63 5e-10
gi|238859541 aldehyde dehydrogenase 4A1 isoform b [Homo sapiens] 63 5e-10
gi|25777734 aldehyde dehydrogenase 4A1 isoform a precursor [Homo... 63 5e-10
gi|223972653 aldehyde dehydrogenase 16 family, member A1 isoform... 36 0.067
>gi|73695881 aldehyde dehydrogenase 3B2 [Homo sapiens]
Length = 385
Score = 788 bits (2035), Expect = 0.0
Identities = 385/385 (100%), Positives = 385/385 (100%)
Query: 1 MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE 60
MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE
Sbjct: 1 MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE 60
Query: 61 ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT 120
ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT
Sbjct: 61 ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT 120
Query: 121 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL 180
KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL
Sbjct: 121 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL 180
Query: 181 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL 240
PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL
Sbjct: 181 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL 240
Query: 241 VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT 300
VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT
Sbjct: 241 VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT 300
Query: 301 SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI 360
SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI
Sbjct: 301 SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI 360
Query: 361 HYPPYTDWNQQLLRWGMGSQSCTLL 385
HYPPYTDWNQQLLRWGMGSQSCTLL
Sbjct: 361 HYPPYTDWNQQLLRWGMGSQSCTLL 385
>gi|73695879 aldehyde dehydrogenase 3B2 [Homo sapiens]
Length = 385
Score = 788 bits (2035), Expect = 0.0
Identities = 385/385 (100%), Positives = 385/385 (100%)
Query: 1 MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE 60
MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE
Sbjct: 1 MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE 60
Query: 61 ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT 120
ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT
Sbjct: 61 ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT 120
Query: 121 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL 180
KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL
Sbjct: 121 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL 180
Query: 181 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL 240
PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL
Sbjct: 181 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL 240
Query: 241 VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT 300
VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT
Sbjct: 241 VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT 300
Query: 301 SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI 360
SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI
Sbjct: 301 SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI 360
Query: 361 HYPPYTDWNQQLLRWGMGSQSCTLL 385
HYPPYTDWNQQLLRWGMGSQSCTLL
Sbjct: 361 HYPPYTDWNQQLLRWGMGSQSCTLL 385
>gi|238814371 aldehyde dehydrogenase 3B1 isoform a [Homo sapiens]
Length = 468
Score = 647 bits (1668), Expect = 0.0
Identities = 322/387 (83%), Positives = 347/387 (89%), Gaps = 2/387 (0%)
Query: 1 MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE 60
MKDE NL +LDS FI KEPFGLVLIIAPWNYPLNLTLV LVGALAAG+CVVLKPSE
Sbjct: 82 MKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSE 141
Query: 61 ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT 120
IS+ EK+LAEVLPQY+DQSCFAVVLGGPQETGQLLEH+ DYIFFTGSPRVGKIVMTAA
Sbjct: 142 ISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFTGSPRVGKIVMTAAA 201
Query: 121 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL 180
KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWF YFNAGQTCVAPDYVLCSPEMQERLL
Sbjct: 202 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLL 261
Query: 181 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL 240
PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQS+ESDRYIAPTVL
Sbjct: 262 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSDESDRYIAPTVL 321
Query: 241 VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT 300
VDVQE EPVMQEEIFGPILPIVNVQS+DEAI+FINR+EKPLALYAFSNSSQVV ++L +T
Sbjct: 322 VDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQT 381
Query: 301 SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI 360
SSG F GN+GF +++L S+PFGGVG SGMGRYHGKF+FDTFSHHR CLL G+EKL +
Sbjct: 382 SSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSPGMEKLNAL 441
Query: 361 HYPPYTDWNQQLLRWGMGSQ--SCTLL 385
YPP + ++L M +Q SCTLL
Sbjct: 442 RYPPQSPRRLRMLLVAMEAQGCSCTLL 468
>gi|4502043 aldehyde dehydrogenase 3B1 isoform a [Homo sapiens]
Length = 468
Score = 647 bits (1668), Expect = 0.0
Identities = 322/387 (83%), Positives = 347/387 (89%), Gaps = 2/387 (0%)
Query: 1 MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSE 60
MKDE NL +LDS FI KEPFGLVLIIAPWNYPLNLTLV LVGALAAG+CVVLKPSE
Sbjct: 82 MKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSE 141
Query: 61 ISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAAT 120
IS+ EK+LAEVLPQY+DQSCFAVVLGGPQETGQLLEH+ DYIFFTGSPRVGKIVMTAA
Sbjct: 142 ISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFTGSPRVGKIVMTAAA 201
Query: 121 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL 180
KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWF YFNAGQTCVAPDYVLCSPEMQERLL
Sbjct: 202 KHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLL 261
Query: 181 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVL 240
PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQS+ESDRYIAPTVL
Sbjct: 262 PALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSDESDRYIAPTVL 321
Query: 241 VDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERT 300
VDVQE EPVMQEEIFGPILPIVNVQS+DEAI+FINR+EKPLALYAFSNSSQVV ++L +T
Sbjct: 322 VDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQT 381
Query: 301 SSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEI 360
SSG F GN+GF +++L S+PFGGVG SGMGRYHGKF+FDTFSHHR CLL G+EKL +
Sbjct: 382 SSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSPGMEKLNAL 441
Query: 361 HYPPYTDWNQQLLRWGMGSQ--SCTLL 385
YPP + ++L M +Q SCTLL
Sbjct: 442 RYPPQSPRRLRMLLVAMEAQGCSCTLL 468
>gi|71773324 aldehyde dehydrogenase 3B1 isoform b [Homo sapiens]
Length = 431
Score = 639 bits (1647), Expect = 0.0
Identities = 316/375 (84%), Positives = 341/375 (90%), Gaps = 2/375 (0%)
Query: 13 KLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEV 72
+LDS FI KEPFGLVLIIAPWNYPLNLTLV LVGALAAG+CVVLKPSEIS+ EK+LAEV
Sbjct: 57 QLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEV 116
Query: 73 LPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGG 132
LPQY+DQSCFAVVLGGPQETGQLLEH+ DYIFFTGSPRVGKIVMTAA KHLTPVTLELGG
Sbjct: 117 LPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGG 176
Query: 133 KNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYG 192
KNPCYVDDNCDPQTVANRVAWF YFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYG
Sbjct: 177 KNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYG 236
Query: 193 DDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVDVQETEPVMQE 252
DDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQS+ESDRYIAPTVLVDVQE EPVMQE
Sbjct: 237 DDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSDESDRYIAPTVLVDVQEMEPVMQE 296
Query: 253 EIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFT 312
EIFGPILPIVNVQS+DEAI+FINR+EKPLALYAFSNSSQVV ++L +TSSG F GN+GF
Sbjct: 297 EIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFM 356
Query: 313 YISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHYPPYTDWNQQL 372
+++L S+PFGGVG SGMGRYHGKF+FDTFSHHR CLL G+EKL + YPP + ++
Sbjct: 357 HMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSPGMEKLNALRYPPQSPRRLRM 416
Query: 373 LRWGMGSQ--SCTLL 385
L M +Q SCTLL
Sbjct: 417 LLVAMEAQGCSCTLL 431
>gi|4557303 aldehyde dehydrogenase 3A2 isoform 2 [Homo sapiens]
Length = 485
Score = 410 bits (1054), Expect = e-114
Identities = 195/373 (52%), Positives = 266/373 (71%), Gaps = 3/373 (0%)
Query: 4 EPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQ 63
+P N+ LD +I +P G+VLII WNYP LT+ L+GA+AAG+ V++KPSE+S+
Sbjct: 82 KPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSE 141
Query: 64 GTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHL 123
T K+LA++LPQYLDQ + V+ GG +ET +LL+ + D+IF+TG+ VGKIVM AA KHL
Sbjct: 142 NTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYTGNTAVGKIVMEAAAKHL 201
Query: 124 TPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPAL 183
TPVTLELGGK+PCY+D +CD V R+ W Y N GQTC+APDY+LC +Q +++ +
Sbjct: 202 TPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKI 261
Query: 184 QSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVDV 243
+ T+ FYG++ + SP+ RIIN + F+R+ +LL ++A GG+++E+ RYIAPTVL DV
Sbjct: 262 KETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKIAFGGETDEATRYIAPTVLTDV 321
Query: 244 QETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSG 303
VMQEEIFGPILPIV V++VDEAI FIN +EKPLALY FS++ +++ +M++ TSSG
Sbjct: 322 DPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSG 381
Query: 304 SFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHYP 363
GN+ + +L S PFGGVG SGMG YHGK +FDTFSH R CLL E ++ YP
Sbjct: 382 GVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKREGANKLRYP 441
Query: 364 PYTDWNQQLLRWG 376
P +Q + WG
Sbjct: 442 PN---SQSKVDWG 451
>gi|73466520 aldehyde dehydrogenase 3A2 isoform 1 [Homo sapiens]
Length = 508
Score = 410 bits (1054), Expect = e-114
Identities = 195/373 (52%), Positives = 266/373 (71%), Gaps = 3/373 (0%)
Query: 4 EPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQ 63
+P N+ LD +I +P G+VLII WNYP LT+ L+GA+AAG+ V++KPSE+S+
Sbjct: 82 KPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSE 141
Query: 64 GTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHL 123
T K+LA++LPQYLDQ + V+ GG +ET +LL+ + D+IF+TG+ VGKIVM AA KHL
Sbjct: 142 NTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYTGNTAVGKIVMEAAAKHL 201
Query: 124 TPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPAL 183
TPVTLELGGK+PCY+D +CD V R+ W Y N GQTC+APDY+LC +Q +++ +
Sbjct: 202 TPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKI 261
Query: 184 QSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVDV 243
+ T+ FYG++ + SP+ RIIN + F+R+ +LL ++A GG+++E+ RYIAPTVL DV
Sbjct: 262 KETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKIAFGGETDEATRYIAPTVLTDV 321
Query: 244 QETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSG 303
VMQEEIFGPILPIV V++VDEAI FIN +EKPLALY FS++ +++ +M++ TSSG
Sbjct: 322 DPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSG 381
Query: 304 SFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHYP 363
GN+ + +L S PFGGVG SGMG YHGK +FDTFSH R CLL E ++ YP
Sbjct: 382 GVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKREGANKLRYP 441
Query: 364 PYTDWNQQLLRWG 376
P +Q + WG
Sbjct: 442 PN---SQSKVDWG 451
>gi|22907049 aldehyde dehydrogenase 3A1 [Homo sapiens]
Length = 453
Score = 407 bits (1045), Expect = e-113
Identities = 191/362 (52%), Positives = 263/362 (72%)
Query: 3 DEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEIS 62
DEP + D ++I EP G+VL+I WNYP NLT+ +VGA+AAG+ VVLKPSE+S
Sbjct: 84 DEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELS 143
Query: 63 QGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKH 122
+ +LA ++PQYLD+ + V+ GG ET +LL+ + D+I +TGS VGKI+MTAA KH
Sbjct: 144 ENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKH 203
Query: 123 LTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPA 182
LTPVTLELGGK+PCYVD NCD R+AW + N+GQTCVAPDY+LC P +Q +++
Sbjct: 204 LTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEK 263
Query: 183 LQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVD 242
L+ ++ FYG+D + S + GRII+ + FQR+ L+ +VA GG + + RYIAPT+L D
Sbjct: 264 LKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTD 323
Query: 243 VQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSS 302
V PVMQEEIFGP+LPIV V+S++EAI+FIN++EKPLALY FS++ +V+ +M+ TSS
Sbjct: 324 VDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSS 383
Query: 303 GSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHY 362
G N+ +I+L S+PFGGVG+SGMG YHGK +F+TFSH R+CL+ P ++ ++ Y
Sbjct: 384 GGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRY 443
Query: 363 PP 364
PP
Sbjct: 444 PP 445
>gi|206597441 aldehyde dehydrogenase 3A1 [Homo sapiens]
Length = 453
Score = 407 bits (1045), Expect = e-113
Identities = 191/362 (52%), Positives = 263/362 (72%)
Query: 3 DEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEIS 62
DEP + D ++I EP G+VL+I WNYP NLT+ +VGA+AAG+ VVLKPSE+S
Sbjct: 84 DEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELS 143
Query: 63 QGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKH 122
+ +LA ++PQYLD+ + V+ GG ET +LL+ + D+I +TGS VGKI+MTAA KH
Sbjct: 144 ENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKH 203
Query: 123 LTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPA 182
LTPVTLELGGK+PCYVD NCD R+AW + N+GQTCVAPDY+LC P +Q +++
Sbjct: 204 LTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEK 263
Query: 183 LQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVD 242
L+ ++ FYG+D + S + GRII+ + FQR+ L+ +VA GG + + RYIAPT+L D
Sbjct: 264 LKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTD 323
Query: 243 VQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSS 302
V PVMQEEIFGP+LPIV V+S++EAI+FIN++EKPLALY FS++ +V+ +M+ TSS
Sbjct: 324 VDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSS 383
Query: 303 GSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHY 362
G N+ +I+L S+PFGGVG+SGMG YHGK +F+TFSH R+CL+ P ++ ++ Y
Sbjct: 384 GGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRY 443
Query: 363 PP 364
PP
Sbjct: 444 PP 445
>gi|206597439 aldehyde dehydrogenase 3A1 [Homo sapiens]
Length = 453
Score = 407 bits (1045), Expect = e-113
Identities = 191/362 (52%), Positives = 263/362 (72%)
Query: 3 DEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEIS 62
DEP + D ++I EP G+VL+I WNYP NLT+ +VGA+AAG+ VVLKPSE+S
Sbjct: 84 DEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELS 143
Query: 63 QGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKH 122
+ +LA ++PQYLD+ + V+ GG ET +LL+ + D+I +TGS VGKI+MTAA KH
Sbjct: 144 ENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKH 203
Query: 123 LTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPA 182
LTPVTLELGGK+PCYVD NCD R+AW + N+GQTCVAPDY+LC P +Q +++
Sbjct: 204 LTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEK 263
Query: 183 LQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVD 242
L+ ++ FYG+D + S + GRII+ + FQR+ L+ +VA GG + + RYIAPT+L D
Sbjct: 264 LKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTD 323
Query: 243 VQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSS 302
V PVMQEEIFGP+LPIV V+S++EAI+FIN++EKPLALY FS++ +V+ +M+ TSS
Sbjct: 324 VDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSS 383
Query: 303 GSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHY 362
G N+ +I+L S+PFGGVG+SGMG YHGK +F+TFSH R+CL+ P ++ ++ Y
Sbjct: 384 GGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRY 443
Query: 363 PP 364
PP
Sbjct: 444 PP 445
>gi|153266822 aldehyde dehydrogenase 1A3 [Homo sapiens]
Length = 512
Score = 141 bits (356), Expect = 9e-34
Identities = 108/341 (31%), Positives = 166/341 (48%), Gaps = 15/341 (4%)
Query: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY- 76
F EP G+ I PWN+PL + + L AL G+ +VLKP+E + T L ++ +
Sbjct: 165 FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAG 224
Query: 77 LDQSCFAVVLG-GPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATK-HLTPVTLELGGK 133
+V G GP + H +++ I FTGS VGK+V AA++ +L VTLELGGK
Sbjct: 225 FPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGK 284
Query: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEM-QERLLPALQSTITRFYG 192
NPC V + D +FN GQ C A V ++ E + +++ R G
Sbjct: 285 NPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVG 344
Query: 193 DDPQSSPNLGRIINQKQFQRLRALLGCGR-----VAIGGQSNESDR-YIAPTVLVDVQET 246
D G I+QKQF ++ L+ G+ + GG + E +I PTV +V +
Sbjct: 345 DPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDN 404
Query: 247 EPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFG 306
+ +EEIFGP+ PI+ +S++E IK N + L F+ + ++ SG+
Sbjct: 405 MRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVW 464
Query: 307 GNEGFTYISLLS-VPFGGVGHSGMGRYHGKFTFDTFSHHRT 346
N Y +L + PFGG SG GR G++ ++ +T
Sbjct: 465 IN---CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKT 502
>gi|4507229 aldehyde dehydrogenase 5A1 isoform 2 precursor [Homo
sapiens]
Length = 535
Score = 135 bits (339), Expect = 8e-32
Identities = 100/338 (29%), Positives = 166/338 (49%), Gaps = 18/338 (5%)
Query: 19 IWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-L 77
+ K+P G+ +I PWN+P + + ALAAG VV+KP+E + + LAE+ Q +
Sbjct: 190 VLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGI 249
Query: 78 DQSCFAVV---LGGPQETGQLL--EHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGG 132
+ V+ +E G+ + + + I FTGS GKI++ A + V++ELGG
Sbjct: 250 PSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGG 309
Query: 133 KNPCYVDDNCD-PQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY 191
P V D+ + Q VA +A + N GQTCV + L + + + A + +
Sbjct: 310 LAPFIVFDSANVDQAVAGAMA-SKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNL 368
Query: 192 --GDDPQSSPNLGRIINQKQFQRLR-----ALLGCGRVAIGGQSNESDR-YIAPTVLVDV 243
G+ + G +IN+K +++ A+ V GG+ ++ + + PT+L +V
Sbjct: 369 RVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNV 428
Query: 244 QETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSG 303
+ EE FGP+ P++ + +EAI N + LA Y +S + ++ E+ G
Sbjct: 429 TQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVG 488
Query: 304 SFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTF 341
G NEG IS + PFGGV SG+GR K+ D +
Sbjct: 489 MVGVNEGL--ISSVECPFGGVKQSGLGREGSKYGIDEY 524
>gi|25777721 aldehyde dehydrogenase 5A1 isoform 1 precursor [Homo
sapiens]
Length = 548
Score = 134 bits (336), Expect = 2e-31
Identities = 104/351 (29%), Positives = 167/351 (47%), Gaps = 31/351 (8%)
Query: 19 IWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYL- 77
+ K+P G+ +I PWN+P + + ALAAG VV+KP+E + + LAEV +L
Sbjct: 190 VLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAEVNQGFLL 249
Query: 78 --DQSCFAVVLGGP--------------QETGQLL--EHKLDYIFFTGSPRVGKIVMTAA 119
D A G P +E G+ + + + I FTGS GKI++ A
Sbjct: 250 DLDPLLLASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHA 309
Query: 120 TKHLTPVTLELGGKNPCYVDDNCD-PQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQER 178
+ V++ELGG P V D+ + Q VA +A + N GQTCV + L + +
Sbjct: 310 ANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMA-SKFRNTGQTCVCSNQFLVQRGIHDA 368
Query: 179 LLPALQSTITRFY--GDDPQSSPNLGRIINQKQFQRLR-----ALLGCGRVAIGGQSNES 231
+ A + + G+ + G +IN+K +++ A+ V GG+ ++
Sbjct: 369 FVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQL 428
Query: 232 DR-YIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSS 290
+ + PT+L +V + EE FGP+ P++ + +EAI N + LA Y +S
Sbjct: 429 GKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDP 488
Query: 291 QVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTF 341
+ ++ E+ G G NEG IS + PFGGV SG+GR K+ D +
Sbjct: 489 AQIWRVAEQLEVGMVGVNEGL--ISSVECPFGGVKQSGLGREGSKYGIDEY 537
>gi|25777732 mitochondrial aldehyde dehydrogenase 2 precursor [Homo
sapiens]
Length = 517
Score = 129 bits (323), Expect = 6e-30
Identities = 91/336 (27%), Positives = 162/336 (48%), Gaps = 13/336 (3%)
Query: 22 EPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQS 80
EP G+ I PWN+PL + L ALA G+ VV+K +E + T +A ++ +
Sbjct: 174 EPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPG 233
Query: 81 CFAVVLG-GPQETGQLLEHK-LDYIFFTGSPRVGKIVMTAA-TKHLTPVTLELGGKNPCY 137
+V G GP + H+ +D + FTGS +G+++ AA + +L VTLELGGK+P
Sbjct: 234 VVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNI 293
Query: 138 VDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYGDDPQ 196
+ + D + + +FN GQ C A ++ + + ++ +R G+
Sbjct: 294 IMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFD 353
Query: 197 SSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRYIAPTVLVDVQETEPVM 250
S G +++ QF+++ + G+ + GG + + +I PTV DVQ+ +
Sbjct: 354 SKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIA 413
Query: 251 QEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEG 310
+EEIFGP++ I+ ++++E + N LA F+ N + + +G+ N
Sbjct: 414 KEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCY 473
Query: 311 FTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRT 346
+ + PFGG SG GR G++ ++ +T
Sbjct: 474 DVFGA--QSPFGGYKMSGSGRELGEYGLQAYTEVKT 507
>gi|115387104 aldehyde dehydrogenase 9A1 [Homo sapiens]
Length = 518
Score = 129 bits (323), Expect = 6e-30
Identities = 96/351 (27%), Positives = 158/351 (45%), Gaps = 19/351 (5%)
Query: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
+EP G+ + I WNYP + ALA G+ +V KPS + + +LAE+ + +
Sbjct: 168 REPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPP 227
Query: 80 SCFAVVLGGPQETGQLLEHKLDY--IFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCY 137
F VV GG TGQ L D + FTGS G +M + K + PVTLELGGK+P
Sbjct: 228 GLFNVVQGGAA-TGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLI 286
Query: 138 VDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRF-YGDDPQ 196
+ +CD + GQ C V E+ ++ + R GD
Sbjct: 287 IFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLL 346
Query: 197 SSPNLGRIINQKQFQRLRALLGC-----GRVAIGGQ-------SNESDRYIAPTVLVDVQ 244
+G +IN+ +R+ + +V GG + Y+ P VL + +
Sbjct: 347 EDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCR 406
Query: 245 ETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGS 304
+ ++EEIFGP++ I++ + E ++ N LA F+ Q ++++ +G+
Sbjct: 407 DDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGT 466
Query: 305 FGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLE 355
N +S + +PFGG SG GR +G+ T + +S +T + +E
Sbjct: 467 CFINN--YNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVE 515
>gi|12007648 aldehyde dehydrogenase 8A1 isoform 1 [Homo sapiens]
Length = 487
Score = 127 bits (320), Expect = 1e-29
Identities = 98/350 (28%), Positives = 174/350 (49%), Gaps = 33/350 (9%)
Query: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
+ P G+ +I+PWN PL L + A+AAG+ V+ KPSE++ T +L ++L + +
Sbjct: 142 RAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPP 201
Query: 80 SCFAVVLG-GPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCY 137
+V G GP+ L+ H ++ I FTGS + + + H ++LELGGKNP
Sbjct: 202 GVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAI 261
Query: 138 VD-----DNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYG 192
+ D C P TV + A N G+ C+ + + L ++
Sbjct: 262 IFEDANLDECIPATVRSSFA-----NQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKV 316
Query: 193 DDPQSSP--NLGRIINQKQFQRLR----------ALLGCG----RVAIGGQSNESDRYIA 236
P S P ++G +I++ +++R A + CG ++++ + N++ ++
Sbjct: 317 GIP-SDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPAR-NQAGYFML 374
Query: 237 PTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQM 296
PTV+ D+++ M EEIFGP+ +V S +E I+ N + LA +S++ V+++
Sbjct: 375 PTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRV 434
Query: 297 LERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRT 346
++ SG N I L++PFGG+ SG+GR K ++D F+ +T
Sbjct: 435 AKKLQSGLVWTN--CWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKT 482
>gi|25777728 aldehyde dehydrogenase 1A2 isoform 3 [Homo sapiens]
Length = 422
Score = 122 bits (307), Expect = 4e-28
Identities = 98/342 (28%), Positives = 160/342 (46%), Gaps = 17/342 (4%)
Query: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY- 76
F EP G+ I PWN+PL + + AL G+ VV+KP+E + + + ++ +
Sbjct: 75 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 134
Query: 77 LDQSCFAVVLG-GPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATK-HLTPVTLELGGK 133
++ G GP + H +D I FTGS VGK++ AA + +L VTLELGGK
Sbjct: 135 FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 194
Query: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYG 192
+P + + D + +FN GQ C A + + E + +++ R G
Sbjct: 195 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVG 254
Query: 193 DDPQSSPNLGRIINQKQFQRLRALLGCG-----RVAIGGQS-NESDRYIAPTVLVDVQET 246
+ G I++KQ+ ++ L+ G ++ GG+ +I PTV +V +
Sbjct: 255 SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDD 314
Query: 247 EPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFG 306
+ +EEIFGP+ I+ +++DE I+ N + L F+N +N+ L SS
Sbjct: 315 MRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND---INKAL-TVSSAMQA 370
Query: 307 GNEGFTYISLLSV--PFGGVGHSGMGRYHGKFTFDTFSHHRT 346
G + L+ PFGG SG GR G+F +S +T
Sbjct: 371 GTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 412
>gi|25777724 aldehyde dehydrogenase 1A2 isoform 1 [Homo sapiens]
Length = 518
Score = 122 bits (307), Expect = 4e-28
Identities = 98/342 (28%), Positives = 160/342 (46%), Gaps = 17/342 (4%)
Query: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY- 76
F EP G+ I PWN+PL + + AL G+ VV+KP+E + + + ++ +
Sbjct: 171 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 230
Query: 77 LDQSCFAVVLG-GPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATK-HLTPVTLELGGK 133
++ G GP + H +D I FTGS VGK++ AA + +L VTLELGGK
Sbjct: 231 FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 290
Query: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYG 192
+P + + D + +FN GQ C A + + E + +++ R G
Sbjct: 291 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVG 350
Query: 193 DDPQSSPNLGRIINQKQFQRLRALLGCG-----RVAIGGQS-NESDRYIAPTVLVDVQET 246
+ G I++KQ+ ++ L+ G ++ GG+ +I PTV +V +
Sbjct: 351 SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDD 410
Query: 247 EPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFG 306
+ +EEIFGP+ I+ +++DE I+ N + L F+N +N+ L SS
Sbjct: 411 MRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND---INKAL-TVSSAMQA 466
Query: 307 GNEGFTYISLLSV--PFGGVGHSGMGRYHGKFTFDTFSHHRT 346
G + L+ PFGG SG GR G+F +S +T
Sbjct: 467 GTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508
>gi|238814322 aldehyde dehydrogenase 1 family, member L2 [Homo
sapiens]
Length = 923
Score = 120 bits (302), Expect = 2e-27
Identities = 97/346 (28%), Positives = 158/346 (45%), Gaps = 17/346 (4%)
Query: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEV-LPQY 76
F KEP G+ II PWNYPL + LAAG+ +VLKP++++ T AE+ +
Sbjct: 579 FTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAG 638
Query: 77 LDQSCFAVVLGGPQETGQLLEHKLDY--IFFTGSPRVGKIVM-TAATKHLTPVTLELGGK 133
+ ++ G GQ L D + FTGS +GK +M + A +L V+LELGGK
Sbjct: 639 FPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGK 698
Query: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRF-YG 192
+P + ++C+ +FN G+ C+A + + + + + I + G
Sbjct: 699 SPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIG 758
Query: 193 DDPQSSPNLGRIINQKQFQRLRALL------GCGRVAIGGQSNESDRYIAPTVLVDVQET 246
D S + G ++ ++L G V G Q ++ PTV DV++
Sbjct: 759 DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDY 818
Query: 247 EPVMQEEIFGPILPIVNVQS--VDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGS 304
+ +EE FGPI+ I Q+ +D ++ N E LA F+ + E+ +G+
Sbjct: 819 MYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGT 878
Query: 305 FGGNEGFTYISL-LSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLL 349
N TY ++ PFGGV SG G+ G+ + + +T L
Sbjct: 879 VFIN---TYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTL 921
>gi|25777730 aldehyde dehydrogenase 1B1 precursor [Homo sapiens]
Length = 517
Score = 119 bits (299), Expect = 4e-27
Identities = 96/341 (28%), Positives = 155/341 (45%), Gaps = 15/341 (4%)
Query: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY- 76
F EP G+ I PWN+PL + L ALA G+ VV+K +E + + LA ++ +
Sbjct: 170 FTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAG 229
Query: 77 LDQSCFAVVLG-GPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAA-TKHLTPVTLELGGK 133
++ G GP + +H +D + FTGS VG ++ AA +L VTLELGGK
Sbjct: 230 FPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGK 289
Query: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYG 192
+P V + D + + +FN GQ C A + L ++ R G
Sbjct: 290 SPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVG 349
Query: 193 DDPQSSPNLGRIINQKQFQRLRALLGCG-----RVAIGGQS-NESDRYIAPTVLVDVQET 246
+ + G ++++QF+R+ + G ++ GG+ E +I PTV VQ+
Sbjct: 350 NPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDD 409
Query: 247 EPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFG 306
+ +EEIFGP+ P+ + ++E ++ N LA F+ + +G+
Sbjct: 410 MRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVW 469
Query: 307 GNEGFTY-ISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRT 346
N TY I PFGG SG GR G+ ++ +T
Sbjct: 470 VN---TYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKT 507
>gi|21361176 aldehyde dehydrogenase 1A1 [Homo sapiens]
Length = 501
Score = 119 bits (298), Expect = 5e-27
Identities = 92/341 (26%), Positives = 161/341 (47%), Gaps = 23/341 (6%)
Query: 22 EPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQS 80
EP G+ I PWN+PL + + + AL+ G+ VV+KP+E + T +A ++ +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 81 CFAVVLG-GPQETGQLLEHK-LDYIFFTGSPRVGKIVMTAATK-HLTPVTLELGGKNPCY 137
+V G GP + H +D + FTGS VGK++ AA K +L VTLELGGK+PC
Sbjct: 218 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
Query: 138 VDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQS 197
V + D +++ GQ C+A + + + + ++ +P +
Sbjct: 278 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLT 337
Query: 198 -SPNLGRIINQKQFQRLRALLGCGRV------AIGGQSNESDRYIAPTVLVDVQETEPVM 250
G I+++Q+ ++ L+ G+ GG ++ PTV +V + +
Sbjct: 338 PGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIA 397
Query: 251 QEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEG 310
+EEIFGP+ I+ +S+D+ IK N + S+ V + +++ + S G
Sbjct: 398 KEEIFGPVQQIMKFKSLDDVIKRANNT-------FYGLSAGVFTKDIDKAITISSALQAG 450
Query: 311 FTYISLLSV-----PFGGVGHSGMGRYHGKFTFDTFSHHRT 346
+++ V PFGG SG GR G++ F ++ +T
Sbjct: 451 TVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKT 491
>gi|21614513 aldehyde dehydrogenase 1 family, member L1 [Homo
sapiens]
Length = 902
Score = 110 bits (274), Expect = 3e-24
Identities = 90/340 (26%), Positives = 149/340 (43%), Gaps = 17/340 (5%)
Query: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEV-LPQYLDQ 79
KEP G+ II PWNYPL + LAAG+ VV+KP++++ T AE+ L + +
Sbjct: 561 KEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPK 620
Query: 80 SCFAVVLGGPQETGQLLEHKLDY--IFFTGSPRVGKIVM-TAATKHLTPVTLELGGKNPC 136
V+ G GQ L D I FTGS VGK +M + A ++ V+LELGGK+P
Sbjct: 621 GVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPL 680
Query: 137 YVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQ 196
+ +CD +FN G+ C+A + + + + + + + +P
Sbjct: 681 IIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPL 740
Query: 197 S-------SPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVDVQETEPV 249
+ ++ ++ + G V G Q + PTV DV++ +
Sbjct: 741 DRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFI 800
Query: 250 MQEEIFGPILPIVNVQ--SVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGG 307
+EE FGP++ I +D + N E LA F+ + ++ +G+
Sbjct: 801 AKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFV 860
Query: 308 NEGFTYISL-LSVPFGGVGHSGMGRYHGKFTFDTFSHHRT 346
N TY ++ PFGG SG G+ G+ + + +T
Sbjct: 861 N---TYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKT 897
>gi|25952152 aldehyde dehydrogenase 8A1 isoform 2 [Homo sapiens]
Length = 433
Score = 109 bits (273), Expect = 4e-24
Identities = 89/334 (26%), Positives = 149/334 (44%), Gaps = 55/334 (16%)
Query: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
+ P G+ +I+PWN PL L + A+AAG+ V+ KPSE++ T +L ++L + +
Sbjct: 142 RAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPP 201
Query: 80 SCFAVVLG-GPQETGQLLEH-KLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCY 137
+V G GP+ L+ H ++ I FTGS + + + H ++LELGGKNP
Sbjct: 202 GVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAI 261
Query: 138 VD-----DNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYG 192
+ D C P TV + A + + C + + LPA
Sbjct: 262 IFEDANLDECIPATVRSSFANQVRSYVKRALAEGAQIWCGEGVDKLSLPA---------- 311
Query: 193 DDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRYIAPTVLVDVQETEPVMQE 252
N++ ++ PTV+ D+++ M E
Sbjct: 312 -----------------------------------RNQAGYFMLPTVITDIKDESCCMTE 336
Query: 253 EIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFT 312
EIFGP+ +V S +E I+ N + LA +S++ V+++ ++ SG N
Sbjct: 337 EIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTN--CW 394
Query: 313 YISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRT 346
I L++PFGG+ SG+GR K ++D F+ +T
Sbjct: 395 LIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKT 428
>gi|25777726 aldehyde dehydrogenase 1A2 isoform 2 [Homo sapiens]
Length = 480
Score = 102 bits (254), Expect = 6e-22
Identities = 88/339 (25%), Positives = 146/339 (43%), Gaps = 49/339 (14%)
Query: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYL 77
F EP G+ I PWN+PL + + AL G+ VV+KP+E + + + ++ +
Sbjct: 171 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKE-- 228
Query: 78 DQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATK-HLTPVTLELGGKNPC 136
VGK++ AA + +L VTLELGGK+P
Sbjct: 229 ---------------------------------VGKLIQEAAGRSNLKRVTLELGGKSPN 255
Query: 137 YVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYGDDP 195
+ + D + +FN GQ C A + + E + +++ R G
Sbjct: 256 IIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPF 315
Query: 196 QSSPNLGRIINQKQFQRLRALLGCG-----RVAIGGQS-NESDRYIAPTVLVDVQETEPV 249
+ G I++KQ+ ++ L+ G ++ GG+ +I PTV +V + +
Sbjct: 316 DPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRI 375
Query: 250 MQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNE 309
+EEIFGP+ I+ +++DE I+ N + L F+N +N+ L SS G
Sbjct: 376 AKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND---INKAL-TVSSAMQAGTV 431
Query: 310 GFTYISLLSV--PFGGVGHSGMGRYHGKFTFDTFSHHRT 346
+ L+ PFGG SG GR G+F +S +T
Sbjct: 432 WINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 470
>gi|11095441 aldehyde dehydrogenase 6A1 precursor [Homo sapiens]
Length = 535
Score = 94.4 bits (233), Expect = 2e-19
Identities = 67/304 (22%), Positives = 135/304 (44%), Gaps = 12/304 (3%)
Query: 17 VFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY 76
++ ++ P G+ IAP+N+P + L + A+ G+ ++KPSE G +LA++L
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 77 -LDQSCFAVVLGGPQETGQLLEHK-LDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKN 134
++ G + + +H + I F GS + G+ + ++H V +G KN
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 135 PCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDD 194
V + + + N++ + AGQ C+A + E ++ L ++
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAG 348
Query: 195 PQSSPNLGRIINQKQFQRLRALLGCGR-----VAIGGQS-----NESDRYIAPTVLVDVQ 244
Q +LG +I + +R+ L+ G + + G+ E+ ++ PT++ +V+
Sbjct: 349 DQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVK 408
Query: 245 ETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGS 304
+EEIFGP+L ++ +++DEAI+ +N F+ + + G
Sbjct: 409 PNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQ 468
Query: 305 FGGN 308
G N
Sbjct: 469 VGVN 472
>gi|188035924 aldehyde dehydrogenase 7 family, member A1 [Homo
sapiens]
Length = 539
Score = 75.1 bits (183), Expect = 1e-13
Identities = 79/348 (22%), Positives = 140/348 (40%), Gaps = 28/348 (8%)
Query: 23 PFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLK----PSEISQGTEKVLAEVLPQY-L 77
P GLV II +N+P+ + A+ G+ + K S IS K++A+VL L
Sbjct: 184 PVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKL 243
Query: 78 DQSCFAVVLGGPQ-ETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPC 136
+ ++ GG T + +++ + FTGS +VGK V + LELGG N
Sbjct: 244 PGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAI 303
Query: 137 YVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQ 196
++ D V + AGQ C + + + ++ L+ + +P
Sbjct: 304 IAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPW 363
Query: 197 SSPNLGRIINQKQFQRLRALLGC--------GRVAIGGQ-SNESDRYIAPTVLVDVQETE 247
L ++ K Q + LG G V GG+ + Y+ PT++ +
Sbjct: 364 DPNVLYGPLHTK--QAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDA 421
Query: 248 PVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGG 307
+ E F PIL + ++ +E + N ++ L+ F+ + + L G G
Sbjct: 422 SIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWL-----GPKGS 476
Query: 308 NEGFTYISL------LSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLL 349
+ G +++ + FGG H+G GR G + + TC +
Sbjct: 477 DCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTI 524
>gi|25777736 aldehyde dehydrogenase 4A1 isoform a precursor [Homo
sapiens]
Length = 563
Score = 62.8 bits (151), Expect = 5e-10
Identities = 100/381 (26%), Positives = 156/381 (40%), Gaps = 60/381 (15%)
Query: 25 GLVLIIAPWNYPLNLTLV--LLVGALAA-GSCVVLKPSEI----SQGTEKVLAEV-LPQY 76
G V I+P+N+ T + L GA A G+ V+ KPS+ S ++L E LP
Sbjct: 202 GFVAAISPFNF----TAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPN 257
Query: 77 LDQSCFAVVLGGPQ--ETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTP------VTL 128
+ Q V GP +T EH L I FTGS K + ++L +
Sbjct: 258 IIQF---VPADGPLFGDTVTSSEH-LCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAG 313
Query: 129 ELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTIT 188
E GGKN +V + D ++V + + GQ C A + + ++ L +
Sbjct: 314 ECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHS 373
Query: 189 RFYGDDPQSSPN--LGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRY-IAPTV 239
R DP +I+ K F R++ L R + GG+ ++S Y + P +
Sbjct: 374 RIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCI 433
Query: 240 LVDVQETEPVMQEEIFGPILPIV---------NVQSVDEAIKFINRQEKPLALYAFSNSS 290
+ EP+M+EEIFGP+L + +Q VD + L FS
Sbjct: 434 VESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSY------GLTGAVFSQDK 487
Query: 291 QVVNQMLE--RTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCL 348
VV + + R ++G+F N+ T + PFGG SG G H+ +
Sbjct: 488 DVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGG------PHY---I 538
Query: 349 LAPSGLEKLKEIHYPPYTDWN 369
L + + +KE H P DW+
Sbjct: 539 LRWTSPQVIKETH-KPLGDWS 558
>gi|238859541 aldehyde dehydrogenase 4A1 isoform b [Homo sapiens]
Length = 503
Score = 62.8 bits (151), Expect = 5e-10
Identities = 100/381 (26%), Positives = 156/381 (40%), Gaps = 60/381 (15%)
Query: 25 GLVLIIAPWNYPLNLTLV--LLVGALAA-GSCVVLKPSEI----SQGTEKVLAEV-LPQY 76
G V I+P+N+ T + L GA A G+ V+ KPS+ S ++L E LP
Sbjct: 142 GFVAAISPFNF----TAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPN 197
Query: 77 LDQSCFAVVLGGPQ--ETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTP------VTL 128
+ Q V GP +T EH L I FTGS K + ++L +
Sbjct: 198 IIQF---VPADGPLFGDTVTSSEH-LCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAG 253
Query: 129 ELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTIT 188
E GGKN +V + D ++V + + GQ C A + + ++ L +
Sbjct: 254 ECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHS 313
Query: 189 RFYGDDPQSSPN--LGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRY-IAPTV 239
R DP +I+ K F R++ L R + GG+ ++S Y + P +
Sbjct: 314 RIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCI 373
Query: 240 LVDVQETEPVMQEEIFGPILPIV---------NVQSVDEAIKFINRQEKPLALYAFSNSS 290
+ EP+M+EEIFGP+L + +Q VD + L FS
Sbjct: 374 VESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSY------GLTGAVFSQDK 427
Query: 291 QVVNQMLE--RTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCL 348
VV + + R ++G+F N+ T + PFGG SG G H+ +
Sbjct: 428 DVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGG------PHY---I 478
Query: 349 LAPSGLEKLKEIHYPPYTDWN 369
L + + +KE H P DW+
Sbjct: 479 LRWTSPQVIKETH-KPLGDWS 498
>gi|25777734 aldehyde dehydrogenase 4A1 isoform a precursor [Homo
sapiens]
Length = 563
Score = 62.8 bits (151), Expect = 5e-10
Identities = 100/381 (26%), Positives = 156/381 (40%), Gaps = 60/381 (15%)
Query: 25 GLVLIIAPWNYPLNLTLV--LLVGALAA-GSCVVLKPSEI----SQGTEKVLAEV-LPQY 76
G V I+P+N+ T + L GA A G+ V+ KPS+ S ++L E LP
Sbjct: 202 GFVAAISPFNF----TAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPN 257
Query: 77 LDQSCFAVVLGGPQ--ETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTP------VTL 128
+ Q V GP +T EH L I FTGS K + ++L +
Sbjct: 258 IIQF---VPADGPLFGDTVTSSEH-LCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAG 313
Query: 129 ELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTIT 188
E GGKN +V + D ++V + + GQ C A + + ++ L +
Sbjct: 314 ECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHS 373
Query: 189 RFYGDDPQSSPN--LGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRY-IAPTV 239
R DP +I+ K F R++ L R + GG+ ++S Y + P +
Sbjct: 374 RIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCI 433
Query: 240 LVDVQETEPVMQEEIFGPILPIV---------NVQSVDEAIKFINRQEKPLALYAFSNSS 290
+ EP+M+EEIFGP+L + +Q VD + L FS
Sbjct: 434 VESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSY------GLTGAVFSQDK 487
Query: 291 QVVNQMLE--RTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCL 348
VV + + R ++G+F N+ T + PFGG SG G H+ +
Sbjct: 488 DVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGG------PHY---I 538
Query: 349 LAPSGLEKLKEIHYPPYTDWN 369
L + + +KE H P DW+
Sbjct: 539 LRWTSPQVIKETH-KPLGDWS 558
>gi|223972653 aldehyde dehydrogenase 16 family, member A1 isoform 2
[Homo sapiens]
Length = 751
Score = 35.8 bits (81), Expect = 0.067
Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 2/113 (1%)
Query: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYLDQS 80
+EP G++ ++ P +PL + LL ALA G+ VV+ PS + + +
Sbjct: 607 REPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATVFPAG 666
Query: 81 CFAVVLGGPQETGQ--LLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELG 131
VV G + L + +++ GS + + V A+ +L PV G
Sbjct: 667 LANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRG 719
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,533,790
Number of Sequences: 37866
Number of extensions: 713606
Number of successful extensions: 1424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1329
Number of HSP's gapped (non-prelim): 41
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.