Search of human proteins with 71773208

Search of human proteins with 71773208

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]
         (462 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]               925   0.0  
gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens]              442   e-124
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]               405   e-113
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa...   243   2e-64
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]           207   2e-53
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                203   2e-52
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]         201   9e-52
gi|32483397 dopamine receptor D4 [Homo sapiens]                       199   4e-51
gi|89191861 dopamine receptor D3 isoform a [Homo sapiens]             191   9e-49
gi|89191863 dopamine receptor D3 isoform e [Homo sapiens]             189   3e-48
gi|194018562 histamine receptor H3 [Homo sapiens]                     177   1e-44
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                167   2e-41
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]    158   1e-38
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]    158   1e-38
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]    158   1e-38
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]    158   1e-38
gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]         157   2e-38
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap...   150   2e-36
gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens]         149   7e-36
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap...   143   4e-34
gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo sap...   140   3e-33
gi|4557265 beta-1-adrenergic receptor [Homo sapiens]                  138   1e-32
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa...   138   1e-32
gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens]          137   2e-32
gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens]         137   2e-32
gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens]         137   2e-32
gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens]         137   2e-32
gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens]         137   2e-32
gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens]         137   2e-32
gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens]         137   2e-32

>gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]
          Length = 462

 Score =  925 bits (2391), Expect = 0.0
 Identities = 462/462 (100%), Positives = 462/462 (100%)

Query: 1   MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF 60
           MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
Sbjct: 1   MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF 60

Query: 61  LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG 120
           LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
Sbjct: 61  LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG 120

Query: 121 QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA 180
           QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
Sbjct: 121 QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA 180

Query: 181 VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR 240
           VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
Sbjct: 181 VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR 240

Query: 241 TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA 300
           TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
Sbjct: 241 TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA 300

Query: 301 LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR 360
           LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
Sbjct: 301 LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR 360

Query: 361 RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK 420
           RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
Sbjct: 361 RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK 420

Query: 421 FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ 462
           FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
Sbjct: 421 FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ 462


>gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens]
          Length = 465

 Score =  442 bits (1138), Expect = e-124
 Identities = 255/470 (54%), Positives = 297/470 (63%), Gaps = 62/470 (13%)

Query: 19  NASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLT 78
           NAS  G    GG A A+          YS      L  + G L++ TV GNVLV+IAV T
Sbjct: 25  NASWNGTEAPGGGARAT---------PYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFT 75

Query: 79  SRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSS 138
           SRAL+APQNLFLVSLASADILVATLV+PFSLANE+M YWYFG+ WC +YLALDVLFCTSS
Sbjct: 76  SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS 135

Query: 139 IVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGA- 197
           IVHLCAISLDRYWS+TQA+EYNLKRTPRR+KA I+ VW+ISAVISFPPL+S+ ++  G  
Sbjct: 136 IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGG 195

Query: 198 ---AYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAP---V 251
              A P+C +ND+ WY++SSCIGSFFAPCLIM LVY RIY++AK RTR    +R P    
Sbjct: 196 PQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA 255

Query: 252 GPDGASPTTENGLGAAAGAGENGHCAPP-----------PADVEP--------DESSAAA 292
            P G +    NGLG    AG  G  A P           PA   P        +ESS++ 
Sbjct: 256 APPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSD 315

Query: 293 ERRRRRGALR--RG--GRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRA 348
              R  G  R  RG  G+ +A A     G      GPGA   G   A    GPG     A
Sbjct: 316 HAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAA----GPGEERVGA 371

Query: 349 SSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGIC 408
           +  S       R R R         Q REKRFTFVLAVV+GVFV+CWFPFFF+Y+L  + 
Sbjct: 372 AKAS-------RWRGR---------QNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAV- 414

Query: 409 REACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRR 458
              C VP  LFKFFFW GYCNSSLNPVIYT+FN DFRR+FK IL R  R+
Sbjct: 415 --GCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRK 462


>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
          Length = 450

 Score =  405 bits (1042), Expect = e-113
 Identities = 238/440 (54%), Positives = 280/440 (63%), Gaps = 34/440 (7%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           YS  A A +AA + FLI+FT+ GN LV++AVLTSR+LRAPQNLFLVSLA+ADILVATL++
Sbjct: 7   YSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLII 66

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
           PFSLANEL+ YWYF + WC VYLALDVLFCTSSIVHLCAISLDRYW+V++A+EYN KRTP
Sbjct: 67  PFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTP 126

Query: 166 RRVKATIVAVWLISAVISFPPLVSLYRQ-PDGAAYPQCGLNDETWYILSSCIGSFFAPCL 224
           RR+K  I+ VWLI+AVIS PPL+    Q P     PQC LN E WYIL+S IGSFFAPCL
Sbjct: 127 RRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCL 186

Query: 225 IMGLVYARIYRVAKLRTRTLSEKRAPVGP---DGASPTTENG----------LGAAAGAG 271
           IM LVY RIY +AK   R     RA  GP   +   P  ++G          L + A A 
Sbjct: 187 IMILVYLRIYLIAKRSNR--RGPRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAR 244

Query: 272 E-NGH--CAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGAD--------- 319
           E NGH        + E  E +          AL   G+ +     GA   D         
Sbjct: 245 EVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEE 304

Query: 320 --GQGAGPGAAESGALTASRSP--GPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ- 374
              +   P A      +A   P   P G    A+ R  +  L R   A      R+ AQ 
Sbjct: 305 EEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRG-QVLLGRGVGAIGGQWWRRRAQL 363

Query: 375 AREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNP 434
            REKRFTFVLAVV+GVFVLCWFPFFFSYSL  IC + C+VP  LF+FFFWIGYCNSSLNP
Sbjct: 364 TREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNP 423

Query: 435 VIYTVFNQDFRRSFKHILFR 454
           VIYT+FNQDFRR+F+ IL R
Sbjct: 424 VIYTIFNQDFRRAFRRILCR 443


>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
           sapiens]
          Length = 422

 Score =  243 bits (621), Expect = 2e-64
 Identities = 146/404 (36%), Positives = 211/404 (52%), Gaps = 38/404 (9%)

Query: 57  VVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAY 116
           ++G LI   V+GN  VV A+   R+L+   N  + SLA  D++V+ LV+P +   +++  
Sbjct: 42  LLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNK 101

Query: 117 WYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVW 176
           W  GQV C +++ALDVL CTSSI+HLCAI+LDRYW++T  ++Y  KRTPRR  A I   W
Sbjct: 102 WTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTW 161

Query: 177 LISAVISFPPLVSLYRQPDGAAYPQ-CGLNDETWYILSSCIGSFFAPCLIMGLVYARIYR 235
           LI  +IS PP++  +R P+  + P  C ++ +  Y + S  G+F+ P L+M ++Y RI+R
Sbjct: 162 LIGFLISIPPMLG-WRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFR 220

Query: 236 VAKLRTRTLSEKRAPVGPD---GASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAA 292
            A+ R R   +K    G D   GASP                  AP P      ES +  
Sbjct: 221 AARFRIRKTVKKVEKTGADTRHGASP------------------APQPKKSVNGESGSRN 262

Query: 293 ER----RRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRA 348
            R     +  GAL   G  R G +G A           + E   L +   P P    S  
Sbjct: 263 WRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPAS-- 320

Query: 349 SSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGIC 408
                      R+  R++  +RK+A ARE++    L ++MG F+LCW PFF    +   C
Sbjct: 321 ---------FERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFC 371

Query: 409 REACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHIL 452
             +C +P  L     W+GY NS LNPVIY  FN+DF+ +FK I+
Sbjct: 372 ESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKII 415


>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
          Length = 443

 Score =  207 bits (526), Expect = 2e-53
 Identities = 139/422 (32%), Positives = 215/422 (50%), Gaps = 42/422 (9%)

Query: 55  AAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELM 114
           A ++  LI   V GNVLV +AV   +AL+   N  +VSLA AD+LVATLVMP+ +  E++
Sbjct: 38  ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVV 97

Query: 115 AYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLK-RTPRRVKATIV 173
             W F ++ C +++ LDV+ CT+SI++LCAIS+DRY +V   + YN +  + RRV   I 
Sbjct: 98  GEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIS 157

Query: 174 AVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARI 233
            VW++S  IS P L  L    + A   +C + +  + + SS + SF+ P ++  LVY +I
Sbjct: 158 IVWVLSFTISCPLLFGL----NNADQNECIIANPAFVVYSSIV-SFYVPFIVTLLVYIKI 212

Query: 234 YRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPP----ADVEPDESS 289
           Y V + R + ++ KR           +     A   A   G+C  P       V    + 
Sbjct: 213 YIVLRRRRKRVNTKR-----------SSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNG 261

Query: 290 AAAERRRRRGALRRGGRRRAGAEGGAGGAD-----------GQGAGPGAAESGALTASRS 338
           +    RRR  A RR               +            Q   P  +  G  +   S
Sbjct: 262 SFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDS 321

Query: 339 PGPGGRLSRASS--RSVEFF------LSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGV 390
           P    +   A    +  + F        + R +  ++ RRK++Q +EK+ T +LA+V+GV
Sbjct: 322 PAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGV 381

Query: 391 FVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKH 450
           F++CW PFF ++ L   C   C +P  L+  F W+GY NS++NP+IYT FN +FR++F  
Sbjct: 382 FIICWLPFFITHILNIHC--DCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLK 439

Query: 451 IL 452
           IL
Sbjct: 440 IL 441


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score =  203 bits (517), Expect = 2e-52
 Identities = 148/476 (31%), Positives = 226/476 (47%), Gaps = 105/476 (22%)

Query: 8   AALAVAAAAGPNASGA--GERGSGGVANASG-----ASWGPPRGQYSAGAVAGLAAVVGF 60
           +A   A + GP   G   G  G GGV  A       +S G P    + G V G AAV G 
Sbjct: 31  SAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGL 90

Query: 61  L---------------IVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           +               I+  V GN+LV+++V  +R L+   N F+V+LA AD+L++  V+
Sbjct: 91  VVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVL 150

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
           PFS   E++ +W FG+ +C V+ A+DVL CT+SI+ LC IS+DRY  V  +++Y    T 
Sbjct: 151 PFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTE 210

Query: 166 RRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLI 225
           R+  A +  +W+++ V+S  PL+  +++P       CG+ +E  Y + S + SF+ P  +
Sbjct: 211 RKAAAILALLWVVALVVSVGPLLG-WKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAV 269

Query: 226 MGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEP 285
           + ++Y R+Y VA+  TR+L                                         
Sbjct: 270 IVVMYCRVYVVARSTTRSL----------------------------------------- 288

Query: 286 DESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRL 345
            E+    ER +    + R   R  GA  GA GA G  +  G     +L            
Sbjct: 289 -EAGVKRERGKASEVVLRIHCR--GAATGADGAHGMRSAKGHTFRSSL------------ 333

Query: 346 SRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLY 405
              S R ++F  SR ++A  +                 LA+V+GVFVLCWFPFFF   L 
Sbjct: 334 ---SVRLLKF--SREKKAAKT-----------------LAIVVGVFVLCWFPFFFVLPLG 371

Query: 406 GICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHIL---FRRRRR 458
            +  +     G +FK  FW+GY NS +NP+IY   +++F+R+F  +L    RRRRR
Sbjct: 372 SLFPQLKPSEG-VFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR 426



 Score = 29.6 bits (65), Expect = 6.0
 Identities = 23/66 (34%), Positives = 24/66 (36%), Gaps = 1/66 (1%)

Query: 279 PPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADG-QGAGPGAAESGALTASR 337
           P  D     SSA        GA    G    G  GGAGG  G  GAG G     +     
Sbjct: 14  PRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPG 73

Query: 338 SPGPGG 343
           S G GG
Sbjct: 74  SAGAGG 79


>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
          Length = 414

 Score =  201 bits (512), Expect = 9e-52
 Identities = 139/409 (33%), Positives = 216/409 (52%), Gaps = 45/409 (11%)

Query: 55  AAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELM 114
           A ++  LI   V GNVLV +AV   +AL+   N  +VSLA AD+LVATLVMP+ +  E++
Sbjct: 38  ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVV 97

Query: 115 AYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLK-RTPRRVKATIV 173
             W F ++ C +++ LDV+ CT+SI++LCAIS+DRY +V   + YN +  + RRV   I 
Sbjct: 98  GEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIS 157

Query: 174 AVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARI 233
            VW++S  IS P L  L    + A   +C + +  + + SS + SF+ P ++  LVY +I
Sbjct: 158 IVWVLSFTISCPLLFGL----NNADQNECIIANPAFVVYSSIV-SFYVPFIVTLLVYIKI 212

Query: 234 YRVAKLRTRTLSEKRA--PVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAA 291
           Y V + R + ++ KR+         +P  E    AA  A E         ++E   S++ 
Sbjct: 213 YIVLRRRRKRVNTKRSSRAFRAHLRAPLKE----AARRAQE--------LEMEMLSSTSP 260

Query: 292 AERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRAS-- 349
            ER R                     +  Q   P  +  G  +   SP    +   A   
Sbjct: 261 PERTR---------------YSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDH 305

Query: 350 ---SRSVEFFLSRRRRARSS---VCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYS 403
              ++  E       + R+S   + RRK++Q +EK+ T +LA+V+GVF++CW PFF ++ 
Sbjct: 306 PKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHI 365

Query: 404 LYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHIL 452
           L   C   C +P  L+  F W+GY NS++NP+IYT FN +FR++F  IL
Sbjct: 366 LNIHC--DCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKIL 412


>gi|32483397 dopamine receptor D4 [Homo sapiens]
          Length = 419

 Score =  199 bits (506), Expect = 4e-51
 Identities = 158/445 (35%), Positives = 213/445 (47%), Gaps = 50/445 (11%)

Query: 27  GSGGVANASG--ASWGPPRGQYSAGAVAGLA-----AVVG--FLIVFTVVGNVLVVIAVL 77
           G+   A+A G  A  GP  G  SAGA AGLA     A+VG   LI   + GN LV ++V 
Sbjct: 2   GNRSTADADGLLAGRGPAAGA-SAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA 60

Query: 78  TSRALRAPQNLFLVSLASADILVATLVMPFSLANELMA-YWYFGQVWCGVYLALDVLFCT 136
           T RAL+ P N F+VSLA+AD+L+A LV+P  + +E+    W      C   +A+DV+ CT
Sbjct: 61  TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT 120

Query: 137 SSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDG 196
           +SI +LCAIS+DR+ +V   + YN +   RR    I A WL+SA ++ P L  L     G
Sbjct: 121 ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGL-NDVRG 179

Query: 197 AAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVA---KLRTRTLSEKRAPVGP 253
                C L D   Y++ S + SFF PC +M L+Y   +R     ++  R     RAP  P
Sbjct: 180 RDPAVCRLEDRD-YVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRP 238

Query: 254 DGASPTTENGLGAAAGAGENG-HCAPPPADVE-----PDESSAAAERRRRRGALRRGGRR 307
            G  P +             G  CAPP   +      PD + AA    +           
Sbjct: 239 SGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCG------- 291

Query: 308 RAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSV 367
                  A G      G   A   A+ A+  P      +R           RRRRA+ + 
Sbjct: 292 -PDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTR-----------RRRRAKIT- 338

Query: 368 CRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGY 427
                   RE++   VL VV+G F+LCW PFF  +    +C  AC VP  L     W+GY
Sbjct: 339 -------GRERKAMRVLPVVVGAFLLCWTPFFVVHITQALC-PACSVPPRLVSAVTWLGY 390

Query: 428 CNSSLNPVIYTVFNQDFRRSFKHIL 452
            NS+LNPVIYTVFN +FR  F+  L
Sbjct: 391 VNSALNPVIYTVFNAEFRNVFRKAL 415


>gi|89191861 dopamine receptor D3 isoform a [Homo sapiens]
          Length = 400

 Score =  191 bits (486), Expect = 9e-49
 Identities = 144/427 (33%), Positives = 207/427 (48%), Gaps = 48/427 (11%)

Query: 30  GVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLF 89
           G  N++GAS   P   Y+    A        LI+  V GN LV +AVL  RAL+   N  
Sbjct: 16  GAENSTGASQARPHAYYALSYCA--------LILAIVFGNGLVCMAVLKERALQTTTNYL 67

Query: 90  LVSLASADILVATLVMPFSLANELMA-YWYFGQVWCGVYLALDVLFCTSSIVHLCAISLD 148
           +VSLA AD+LVATLVMP+ +  E+    W F ++ C V++ LDV+ CT+SI++LCAIS+D
Sbjct: 68  VVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISID 127

Query: 149 RYWSVTQAVEYNL---KRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLN 205
           RY +V   V Y     + + RRV   I AVW+++  +S P L       D      C ++
Sbjct: 128 RYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV---CSIS 184

Query: 206 DETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLG 265
           +  + I SS + SF+ P  +  LVYARIY V K R R    KR     +    +   G  
Sbjct: 185 NPDFVIYSSVV-SFYLPFGVTVLVYARIYVVLKQRRR----KRILTRQNSQCNSVRPGFP 239

Query: 266 AAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGP 325
                      +P PA +E     +  +      AL   G +  G E            P
Sbjct: 240 QQT-------LSPDPAHLELKRYYSICQDT----ALGGPGFQERGGELKREEKTRNSLSP 288

Query: 326 GAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLA 385
             A   +L   +     GRLS +               +    + +    REK+ T ++A
Sbjct: 289 TIAPKLSLEVRKL--SNGRLSTS--------------LKLGPLQPRGVPLREKKATQMVA 332

Query: 386 VVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFR 445
           +V+G F++CW PFF ++ L   C + C V   L+    W+GY NS+LNPVIYT FN +FR
Sbjct: 333 IVLGAFIVCWLPFFLTHVLNTHC-QTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFR 391

Query: 446 RSFKHIL 452
           ++F  IL
Sbjct: 392 KAFLKIL 398


>gi|89191863 dopamine receptor D3 isoform e [Homo sapiens]
          Length = 367

 Score =  189 bits (481), Expect = 3e-48
 Identities = 142/427 (33%), Positives = 199/427 (46%), Gaps = 81/427 (18%)

Query: 30  GVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLF 89
           G  N++GAS   P   Y+    A        LI+  V GN LV +AVL  RAL+   N  
Sbjct: 16  GAENSTGASQARPHAYYALSYCA--------LILAIVFGNGLVCMAVLKERALQTTTNYL 67

Query: 90  LVSLASADILVATLVMPFSLANELMA-YWYFGQVWCGVYLALDVLFCTSSIVHLCAISLD 148
           +VSLA AD+LVATLVMP+ +  E+    W F ++ C V++ LDV+ CT+SI++LCAIS+D
Sbjct: 68  VVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISID 127

Query: 149 RYWSVTQAVEYNL---KRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLN 205
           RY +V   V Y     + + RRV   I AVW+++  +S P L       D      C ++
Sbjct: 128 RYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV---CSIS 184

Query: 206 DETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLG 265
           +  + I SS + SF+ P  +  LVYARIY V K R R    KR     +    +   G  
Sbjct: 185 NPDFVIYSSVV-SFYLPFGVTVLVYARIYVVLKQRRR----KRILTRQNSQCNSVRPGFP 239

Query: 266 AAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGP 325
                      +P PA +E     +  +                         D    GP
Sbjct: 240 QQT-------LSPDPAHLELKRYYSICQ-------------------------DTALGGP 267

Query: 326 GAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLA 385
           G  E            GG L R                     R  +   REK+ T ++A
Sbjct: 268 GFQER-----------GGELKREEK-----------------TRNSLMPLREKKATQMVA 299

Query: 386 VVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFR 445
           +V+G F++CW PFF ++ L   C + C V   L+    W+GY NS+LNPVIYT FN +FR
Sbjct: 300 IVLGAFIVCWLPFFLTHVLNTHC-QTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFR 358

Query: 446 RSFKHIL 452
           ++F  IL
Sbjct: 359 KAFLKIL 365


>gi|194018562 histamine receptor H3 [Homo sapiens]
          Length = 445

 Score =  177 bits (450), Expect = 1e-44
 Identities = 140/456 (30%), Positives = 214/456 (46%), Gaps = 56/456 (12%)

Query: 17  GP-NASGA--GERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVV 73
           GP NASGA  GE  + G A    A+W            A LAA++  LIV TV+GN LV+
Sbjct: 8   GPLNASGALAGEAAAAGGARGFSAAW-----------TAVLAALMALLIVATVLGNALVM 56

Query: 74  IAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVL 133
           +A +   +LR   N FL++LA +D LV    +P  +   L   W FG+  C ++L +D L
Sbjct: 57  LAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYL 116

Query: 134 FCTSSIVHLCAISLDRYWSVTQAVEYNLKR-TPRRVKATIVAVWLISAVISFPPLVSLYR 192
            CTSS  ++  IS DR+ SVT+AV Y  ++   RR    ++ VW+++ ++  P ++S   
Sbjct: 117 LCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEY 176

Query: 193 QPDGAAYPQCGLNDE---TWY-ILSSCIGSFFAPCLIMGL----VYARIYRVAKLRTRTL 244
              G++ P+     E    WY ++++    FF P L +      +Y  I R  +LR    
Sbjct: 177 LSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGA 236

Query: 245 SEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRG 304
            E   P  P  A P+     G   G  + GH    P                R G     
Sbjct: 237 REAAGPEPPPEAQPSPPPPPG-CWGCWQKGHGEAMPL--------------HRYGV---- 277

Query: 305 GRRRAGAEG-----GAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSR 359
           G    GAE      G GG  G  A P ++   +   +  P    R S+ S+ S    L +
Sbjct: 278 GEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSAS--LEK 335

Query: 360 RRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQ---VPG 416
           R +  S    ++   +R+++    LAV++ +F LCW P    Y+L  I R AC    VP 
Sbjct: 336 RMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAP----YTLLMIIRAACHGHCVPD 391

Query: 417 PLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHIL 452
             ++  FW+ + NS++NPV+Y + +  FRR+F  +L
Sbjct: 392 YWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLL 427


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score =  167 bits (423), Expect = 2e-41
 Identities = 88/231 (38%), Positives = 140/231 (60%), Gaps = 4/231 (1%)

Query: 17  GPNASGAGERGSGGVANASG---ASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVV 73
           G N S     G    AN +G    S      Q        +  V+G  I+F +VGN+LV+
Sbjct: 8   GHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVI 67

Query: 74  IAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVL 133
           ++V  +R LR P N F+V+LA AD+L++  V+PFS A E++ YW  G+++C ++ A+DVL
Sbjct: 68  LSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVL 127

Query: 134 FCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQ 193
            CT+SI+ LCAIS+DRY  V  +++Y    T R+    +++VW++S VIS  PL+  +++
Sbjct: 128 CCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLG-WKE 186

Query: 194 PDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTL 244
           P      +CG+ +E +Y L S +GSF+ P  ++ ++Y R+Y VAK  T+ L
Sbjct: 187 PAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNL 237



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 43/106 (40%), Positives = 62/106 (58%), Gaps = 8/106 (7%)

Query: 364 RSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFF 423
           RSS+  +    +REK+    L +V+G+F+LCW PFF +  L G      + P  +FK  F
Sbjct: 276 RSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPL-GSLFSTLKPPDAVFKVVF 334

Query: 424 WIGYCNSSLNPVIYTVFNQDFRRSFKHIL-------FRRRRRGFRQ 462
           W+GY NS LNP+IY   +++F+R+F  IL        RRRRR  R+
Sbjct: 335 WLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRR 380


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score =  158 bits (399), Expect = 1e-38
 Identities = 85/217 (39%), Positives = 134/217 (61%), Gaps = 3/217 (1%)

Query: 28  SGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQN 87
           SG  +++S  +  P     S   + G+  ++G LI+F V+GN+LV+++V   R L +  +
Sbjct: 5   SGNASDSSNCTQPPAPVNISKAILLGV--ILGGLILFGVLGNILVILSVACHRHLHSVTH 62

Query: 88  LFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISL 147
            ++V+LA AD+L+ + V+PFS   E++ YW FG+V+C ++ A+DVL CT+SI+ LC IS+
Sbjct: 63  YYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISI 122

Query: 148 DRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDE 207
           DRY  V+  + Y    T RR    ++ VW +S VIS  PL   +RQP       C +N+E
Sbjct: 123 DRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFG-WRQPAPEDETICQINEE 181

Query: 208 TWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTL 244
             Y+L S +GSF+ P  I+ ++Y R+Y VAK  +R L
Sbjct: 182 PGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGL 218



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 12/125 (9%)

Query: 328 AESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVV 387
           +E   L   R   P G    AS+++   F  R  +            +REK+    L +V
Sbjct: 229 SEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF-----------SREKKAAKTLGIV 277

Query: 388 MGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRS 447
           +G FVLCW PFF    + G      +    +FK  FW+GY NS +NP+IY   +Q+F+++
Sbjct: 278 VGCFVLCWLPFFLVMPI-GSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKA 336

Query: 448 FKHIL 452
           F+++L
Sbjct: 337 FQNVL 341


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score =  158 bits (399), Expect = 1e-38
 Identities = 85/217 (39%), Positives = 134/217 (61%), Gaps = 3/217 (1%)

Query: 28  SGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQN 87
           SG  +++S  +  P     S   + G+  ++G LI+F V+GN+LV+++V   R L +  +
Sbjct: 5   SGNASDSSNCTQPPAPVNISKAILLGV--ILGGLILFGVLGNILVILSVACHRHLHSVTH 62

Query: 88  LFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISL 147
            ++V+LA AD+L+ + V+PFS   E++ YW FG+V+C ++ A+DVL CT+SI+ LC IS+
Sbjct: 63  YYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISI 122

Query: 148 DRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDE 207
           DRY  V+  + Y    T RR    ++ VW +S VIS  PL   +RQP       C +N+E
Sbjct: 123 DRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFG-WRQPAPEDETICQINEE 181

Query: 208 TWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTL 244
             Y+L S +GSF+ P  I+ ++Y R+Y VAK  +R L
Sbjct: 182 PGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGL 218



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 12/125 (9%)

Query: 328 AESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVV 387
           +E   L   R   P G    AS+++   F  R  +            +REK+    L +V
Sbjct: 229 SEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF-----------SREKKAAKTLGIV 277

Query: 388 MGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRS 447
           +G FVLCW PFF    + G      +    +FK  FW+GY NS +NP+IY   +Q+F+++
Sbjct: 278 VGCFVLCWLPFFLVMPI-GSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKA 336

Query: 448 FKHIL 452
           F+++L
Sbjct: 337 FQNVL 341


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score =  158 bits (399), Expect = 1e-38
 Identities = 85/217 (39%), Positives = 134/217 (61%), Gaps = 3/217 (1%)

Query: 28  SGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQN 87
           SG  +++S  +  P     S   + G+  ++G LI+F V+GN+LV+++V   R L +  +
Sbjct: 5   SGNASDSSNCTQPPAPVNISKAILLGV--ILGGLILFGVLGNILVILSVACHRHLHSVTH 62

Query: 88  LFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISL 147
            ++V+LA AD+L+ + V+PFS   E++ YW FG+V+C ++ A+DVL CT+SI+ LC IS+
Sbjct: 63  YYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISI 122

Query: 148 DRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDE 207
           DRY  V+  + Y    T RR    ++ VW +S VIS  PL   +RQP       C +N+E
Sbjct: 123 DRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFG-WRQPAPEDETICQINEE 181

Query: 208 TWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTL 244
             Y+L S +GSF+ P  I+ ++Y R+Y VAK  +R L
Sbjct: 182 PGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGL 218



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 12/125 (9%)

Query: 328 AESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVV 387
           +E   L   R   P G    AS+++   F  R  +            +REK+    L +V
Sbjct: 229 SEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF-----------SREKKAAKTLGIV 277

Query: 388 MGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRS 447
           +G FVLCW PFF    + G      +    +FK  FW+GY NS +NP+IY   +Q+F+++
Sbjct: 278 VGCFVLCWLPFFLVMPI-GSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKA 336

Query: 448 FKHIL 452
           F+++L
Sbjct: 337 FQNVL 341


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score =  158 bits (399), Expect = 1e-38
 Identities = 85/217 (39%), Positives = 134/217 (61%), Gaps = 3/217 (1%)

Query: 28  SGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQN 87
           SG  +++S  +  P     S   + G+  ++G LI+F V+GN+LV+++V   R L +  +
Sbjct: 5   SGNASDSSNCTQPPAPVNISKAILLGV--ILGGLILFGVLGNILVILSVACHRHLHSVTH 62

Query: 88  LFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISL 147
            ++V+LA AD+L+ + V+PFS   E++ YW FG+V+C ++ A+DVL CT+SI+ LC IS+
Sbjct: 63  YYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISI 122

Query: 148 DRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDE 207
           DRY  V+  + Y    T RR    ++ VW +S VIS  PL   +RQP       C +N+E
Sbjct: 123 DRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFG-WRQPAPEDETICQINEE 181

Query: 208 TWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTL 244
             Y+L S +GSF+ P  I+ ++Y R+Y VAK  +R L
Sbjct: 182 PGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGL 218



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 12/125 (9%)

Query: 328 AESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVV 387
           +E   L   R   P G    AS+++   F  R  +            +REK+    L +V
Sbjct: 229 SEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKF-----------SREKKAAKTLGIV 277

Query: 388 MGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRS 447
           +G FVLCW PFF    + G      +    +FK  FW+GY NS +NP+IY   +Q+F+++
Sbjct: 278 VGCFVLCWLPFFLVMPI-GSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKA 336

Query: 448 FKHIL 452
           F+++L
Sbjct: 337 FQNVL 341


>gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
          Length = 460

 Score =  157 bits (397), Expect = 2e-38
 Identities = 115/425 (27%), Positives = 201/425 (47%), Gaps = 33/425 (7%)

Query: 51  VAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLA 110
           VA +    G L + TV GN+LV+I+   +  L+   N FL+SLA AD+++ T  M     
Sbjct: 25  VAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTT 84

Query: 111 NELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKA 170
             LM +W  G + C ++LALD +   +S+++L  IS DRY+SVT+ + Y  KRTPRR   
Sbjct: 85  YLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAAL 144

Query: 171 TIVAVWLISAVISFPPLVSLYRQPDG---AAYPQCGLNDETWYILS--SCIGSFFAPCLI 225
            I   WL+S V+ + P +  ++   G       QC +   +  I++  + + +F+ P  +
Sbjct: 145 MIGLAWLVSFVL-WAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTV 203

Query: 226 MGLVYARIYRVAKLRTRTLSEKRAPVGP---DGASPTTENGLGAAAGAGEN--GHCAPPP 280
           M  +Y RIYR  + R R L+  +    P    G+S ++E     A G+ E   G C    
Sbjct: 204 MCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCC--- 260

Query: 281 ADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPG 340
                      A R  +  + +       G+      ++G+  G        +    +  
Sbjct: 261 -------RCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQA 313

Query: 341 PGGRLSRASSRSVEFFLSRRR---------RARSSVCRRKV-AQAREKRFTFVLAVVMGV 390
           P  +  R+S  +V+    + R         R +  + +RK  +  +EK+    L+ ++  
Sbjct: 314 PTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLA 373

Query: 391 FVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKH 450
           F+L W P+     +   C++   VP  L++  +W+ Y NS++NP+ Y + N+ FR +F+ 
Sbjct: 374 FILTWTPYNIMVLVSTFCKDC--VPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRL 431

Query: 451 ILFRR 455
           +L  R
Sbjct: 432 LLLCR 436


>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
           sapiens]
          Length = 377

 Score =  150 bits (379), Expect = 2e-36
 Identities = 106/314 (33%), Positives = 157/314 (50%), Gaps = 28/314 (8%)

Query: 19  NASGAGERGSGGVANASGAS--WGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAV 76
           +A G  +  S    NA+  S  W P   Q        LA V+  + + TV+ N  V+  +
Sbjct: 7   SAEGLPQEASNRSLNATETSEAWDPRTLQ---ALKISLAVVLSVITLATVLSNAFVLTTI 63

Query: 77  LTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCT 136
           L +R L  P N  + SLA+ D+LV+ LVMP S+A  +   W FGQ+ C ++L+ D+  CT
Sbjct: 64  LLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCT 123

Query: 137 SSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDG 196
           +SI+HLC I+LDRYW++T A+EY+ +RT       I  VW IS  IS PPL   +RQ   
Sbjct: 124 ASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPL--FWRQAKA 181

Query: 197 -AAYPQCGLN-DETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPD 254
                 C +N  +  Y + S  G+F+ P +++ ++Y RIYR A  R R L+    P    
Sbjct: 182 QEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAA--RNRILN----PPSLY 235

Query: 255 GASPTTENGLGAAAGAG----------ENGHCAPPPA---DVEPDESSAAAERRRRRGAL 301
           G   TT + +  +AG+            + H A  P     V+   + +A ER+R   A 
Sbjct: 236 GKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAAR 295

Query: 302 RRGGRRRAGAEGGA 315
            R   +  G   GA
Sbjct: 296 ERKATKILGIILGA 309



 Score =  102 bits (253), Expect = 1e-21
 Identities = 42/94 (44%), Positives = 70/94 (74%), Gaps = 1/94 (1%)

Query: 363 ARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFF 422
           A S++ R++++ ARE++ T +L +++G F++CW PFF    +  ICR++C +   LF FF
Sbjct: 282 ADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFF 341

Query: 423 FWIGYCNSSLNPVIYTVFNQDFRRSFKHIL-FRR 455
            W+GY NS +NP+IYTVFN++FR++F+ I+ FR+
Sbjct: 342 TWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRK 375


>gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens]
          Length = 479

 Score =  149 bits (375), Expect = 7e-36
 Identities = 124/478 (25%), Positives = 205/478 (42%), Gaps = 57/478 (11%)

Query: 24  GERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALR 83
           G  G+  V   + +S      +Y    +  +A V G L + TVVGN+LV++++  +R L+
Sbjct: 9   GSSGNQSVRLVTSSS----HNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQ 64

Query: 84  APQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLC 143
              N FL SLA AD+++    M       +  YW  G V C ++LALD +   +S+++L 
Sbjct: 65  TVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLL 124

Query: 144 AISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPL------VSLYRQPDGA 197
            IS DRY+ VT+ + Y  +RT +     I A W++S V+  P +      V     PD  
Sbjct: 125 IISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQ 184

Query: 198 AYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARI-----YRVAKLRTRTLSEKRAPVG 252
            + Q   N    +   + I +F+ P +IM ++Y  I      RV K R     EK+A   
Sbjct: 185 CFIQFLSNPAVTF--GTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTL 242

Query: 253 PDGASPTTENGL------GAAAGAGENGHC--APPPADVEP------------DESSAAA 292
               SP  +  +       AA     NG    APPPA   P              S +A 
Sbjct: 243 AFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSAT 302

Query: 293 ERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPG------------ 340
           +  + R A              A     +   P +  S     ++  G            
Sbjct: 303 QNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPA 362

Query: 341 -PGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFF 399
            P G   R ++     F S    AR+ V +++   ARE++ T  +  ++  F+L W P+ 
Sbjct: 363 TPAG--MRPAANVARKFAS---IARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYN 417

Query: 400 FSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRR 457
               +   C+    +P  ++   +W+ Y NS++NP  Y + N  F+++F+H+L  + R
Sbjct: 418 VMVLVNTFCQSC--IPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR 473


>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
           sapiens]
          Length = 390

 Score =  143 bits (360), Expect = 4e-34
 Identities = 89/273 (32%), Positives = 134/273 (49%), Gaps = 13/273 (4%)

Query: 54  LAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANEL 113
           L  ++  + + T + N  V+  V  +R L  P N  + SLA  D+LV+ LVMP S    +
Sbjct: 52  LVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTV 111

Query: 114 MAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIV 173
              W  GQV C  +L+ D+  CT+SI+HLC I+LDRYW++T AVEY+ KRTP+R    I 
Sbjct: 112 TGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIA 171

Query: 174 AVWLISAVISFPPLVSLYRQPDG-AAYPQCGLN-DETWYILSSCIGSFFAPCLIMGLVYA 231
            VW+ S  IS PP    +RQ        +C +N D   Y + S +G+F+ P L++  +Y 
Sbjct: 172 LVWVFSISISLPPF--FWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYG 229

Query: 232 RIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPAD--------- 282
           RIY  A+ R    +  R       A   T++    ++    N      P++         
Sbjct: 230 RIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQ 289

Query: 283 VEPDESSAAAERRRRRGALRRGGRRRAGAEGGA 315
           V+   S A  E+++   A  R   +  G   GA
Sbjct: 290 VKVRVSDALLEKKKLMAARERKATKTLGIILGA 322



 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 34/84 (40%), Positives = 58/84 (69%)

Query: 369 RRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K+  ARE++ T  L +++G F++CW PFF    +  IC++AC     +F FF W+GY 
Sbjct: 301 KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL 360

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS +NP+IYT+ N+DF+++F  ++
Sbjct: 361 NSLINPIIYTMSNEDFKQAFHKLI 384


>gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo
           sapiens]
          Length = 365

 Score =  140 bits (352), Expect = 3e-33
 Identities = 72/179 (40%), Positives = 106/179 (59%), Gaps = 1/179 (0%)

Query: 61  LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG 120
           +   T + N+ V++A+ T++ L  P N  + SLA  D+LVA LVMP S+   +M  W  G
Sbjct: 32  ITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLG 91

Query: 121 QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA 180
              C V+L++D+  CT SI+HLC I+LDRYW++T A+EY  KRT +R    I+ VW IS 
Sbjct: 92  YFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISI 151

Query: 181 VISFPPLVSLYRQPDGAAYPQCGL-NDETWYILSSCIGSFFAPCLIMGLVYARIYRVAK 238
            IS PPL     +       QC + +D   Y + S +G+F+ P  ++ ++Y RIY  AK
Sbjct: 152 FISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAK 210



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 29/84 (34%), Positives = 52/84 (61%), Gaps = 2/84 (2%)

Query: 369 RRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           R++++  RE++   +L +++G F+L W PFF    + G+      V   +  F  W+GY 
Sbjct: 278 RQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGL--SIYTVSSEVADFLTWLGYV 335

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS +NP++YT FN+DF+ +FK ++
Sbjct: 336 NSLINPLLYTSFNEDFKLAFKKLI 359


>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
          Length = 477

 Score =  138 bits (347), Expect = 1e-32
 Identities = 94/307 (30%), Positives = 151/307 (49%), Gaps = 24/307 (7%)

Query: 14  AAAGPNASGAGERGSGGVANASGASWGPPRGQ----YSAGAVAGLAAVVGFLIVFTVVGN 69
           ++A P   GA       V  +  AS  PP  +     S    AG+  ++  +++  V GN
Sbjct: 17  SSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAGMGLLMALIVLLIVAGN 76

Query: 70  VLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLA 129
           VLV++A+  +  L+   NLF++SLASAD+++  LV+PF     +   W +G  +C ++ +
Sbjct: 77  VLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTS 136

Query: 130 LDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVS 189
           +DVL  T+SI  LC I+LDRY ++T    Y    T  R +  +  VW ISA++SF P++ 
Sbjct: 137 VDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPILM 196

Query: 190 LYRQPDGAAYPQCGLND--------ETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRT 241
            + + +     +C  ND           Y ++S + SF+ P  IM  VY R++R A+ + 
Sbjct: 197 HWWRAESDEARRC-YNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQV 255

Query: 242 RTLS--EKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRG 299
           + +   E+R   GP  A P + +     A        APPP    P  ++A A     R 
Sbjct: 256 KKIDSCERRFLGGP--ARPPSPSPSPVPAP-------APPPGPPRPAAAAATAPLANGRA 306

Query: 300 ALRRGGR 306
             RR  R
Sbjct: 307 GKRRPSR 313



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 45/125 (36%), Positives = 67/125 (53%), Gaps = 7/125 (5%)

Query: 338 SPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFP 397
           +P PG     A++ +      R  + R S    ++   RE++    L ++MGVF LCW P
Sbjct: 284 APPPGPPRPAAAAATAPLANGRAGKRRPS----RLVALREQKALKTLGIIMGVFTLCWLP 339

Query: 398 FFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRR 457
           FF +  +    RE   VP  LF FF W+GY NS+ NP+IY   + DFR++F+ +L   RR
Sbjct: 340 FFLANVVKAFHREL--VPDRLFVFFNWLGYANSAFNPIIY-CRSPDFRKAFQGLLCCARR 396

Query: 458 RGFRQ 462
              R+
Sbjct: 397 AARRR 401


>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
           sapiens]
          Length = 366

 Score =  138 bits (347), Expect = 1e-32
 Identities = 78/189 (41%), Positives = 110/189 (58%), Gaps = 7/189 (3%)

Query: 61  LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG 120
           L + T   N LV+ A++ +R L  P N  + SLA  D LVA LVMPFS+   +   W  G
Sbjct: 33  LALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMG 92

Query: 121 QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA 180
           QV C ++L++D+  CT SI+HL AI+LDRY ++T AVEY  KRTP+     I  VW+IS 
Sbjct: 93  QVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISV 152

Query: 181 VISFPPLVSLYRQPDGAAYPQCGL-NDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKL 239
            IS PPL   +R    +   +C + +D     + S  G+F+ P  ++ ++Y +IYR AK 
Sbjct: 153 FISMPPL--FWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAK- 209

Query: 240 RTRTLSEKR 248
              TL  KR
Sbjct: 210 ---TLYHKR 215



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 31/84 (36%), Positives = 57/84 (67%), Gaps = 1/84 (1%)

Query: 369 RRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           R+K++  RE++    L +++G FV+CW PFF    +  +C + C++   +  F  W+GY 
Sbjct: 280 RQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSNFLAWLGYL 338

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS +NP+IYT+FN+DF+++F+ ++
Sbjct: 339 NSLINPLIYTIFNEDFKKAFQKLV 362


>gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens]
          Length = 466

 Score =  137 bits (345), Expect = 2e-32
 Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           Y    V  +  V G L + T++GN+LV++++  +R L+   N FL SLA AD+++    M
Sbjct: 18  YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
                  ++ YW  G V C ++LALD +   +S+++L  IS DRY+ VT+ + Y +KRT 
Sbjct: 78  NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137

Query: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
           +     I A W++S ++  P       +V +    DG  Y Q   N    +   + I +F
Sbjct: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195

Query: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
           + P +IM ++Y  I R +K R +   +K+ PV   D  SP+   G               
Sbjct: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253

Query: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
           G      +NG     P     V+ +E  ++ +       A           E     + G
Sbjct: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313

Query: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
                 + ++     +++P         ++  V     +    + ++  RK+ +     A
Sbjct: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373

Query: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K       + T  +  ++  F++ W P+     +   C  A  +P  ++   +W+ Y 
Sbjct: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS++NP  Y + N  F+++FKH+L
Sbjct: 432 NSTINPACYALCNATFKKTFKHLL 455


>gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens]
          Length = 466

 Score =  137 bits (345), Expect = 2e-32
 Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           Y    V  +  V G L + T++GN+LV++++  +R L+   N FL SLA AD+++    M
Sbjct: 18  YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
                  ++ YW  G V C ++LALD +   +S+++L  IS DRY+ VT+ + Y +KRT 
Sbjct: 78  NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137

Query: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
           +     I A W++S ++  P       +V +    DG  Y Q   N    +   + I +F
Sbjct: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195

Query: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
           + P +IM ++Y  I R +K R +   +K+ PV   D  SP+   G               
Sbjct: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253

Query: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
           G      +NG     P     V+ +E  ++ +       A           E     + G
Sbjct: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313

Query: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
                 + ++     +++P         ++  V     +    + ++  RK+ +     A
Sbjct: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373

Query: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K       + T  +  ++  F++ W P+     +   C  A  +P  ++   +W+ Y 
Sbjct: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS++NP  Y + N  F+++FKH+L
Sbjct: 432 NSTINPACYALCNATFKKTFKHLL 455


>gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens]
          Length = 466

 Score =  137 bits (345), Expect = 2e-32
 Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           Y    V  +  V G L + T++GN+LV++++  +R L+   N FL SLA AD+++    M
Sbjct: 18  YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
                  ++ YW  G V C ++LALD +   +S+++L  IS DRY+ VT+ + Y +KRT 
Sbjct: 78  NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137

Query: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
           +     I A W++S ++  P       +V +    DG  Y Q   N    +   + I +F
Sbjct: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195

Query: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
           + P +IM ++Y  I R +K R +   +K+ PV   D  SP+   G               
Sbjct: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253

Query: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
           G      +NG     P     V+ +E  ++ +       A           E     + G
Sbjct: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313

Query: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
                 + ++     +++P         ++  V     +    + ++  RK+ +     A
Sbjct: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373

Query: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K       + T  +  ++  F++ W P+     +   C  A  +P  ++   +W+ Y 
Sbjct: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS++NP  Y + N  F+++FKH+L
Sbjct: 432 NSTINPACYALCNATFKKTFKHLL 455


>gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens]
          Length = 466

 Score =  137 bits (345), Expect = 2e-32
 Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           Y    V  +  V G L + T++GN+LV++++  +R L+   N FL SLA AD+++    M
Sbjct: 18  YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
                  ++ YW  G V C ++LALD +   +S+++L  IS DRY+ VT+ + Y +KRT 
Sbjct: 78  NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137

Query: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
           +     I A W++S ++  P       +V +    DG  Y Q   N    +   + I +F
Sbjct: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195

Query: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
           + P +IM ++Y  I R +K R +   +K+ PV   D  SP+   G               
Sbjct: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253

Query: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
           G      +NG     P     V+ +E  ++ +       A           E     + G
Sbjct: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313

Query: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
                 + ++     +++P         ++  V     +    + ++  RK+ +     A
Sbjct: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373

Query: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K       + T  +  ++  F++ W P+     +   C  A  +P  ++   +W+ Y 
Sbjct: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS++NP  Y + N  F+++FKH+L
Sbjct: 432 NSTINPACYALCNATFKKTFKHLL 455


>gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens]
          Length = 466

 Score =  137 bits (345), Expect = 2e-32
 Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           Y    V  +  V G L + T++GN+LV++++  +R L+   N FL SLA AD+++    M
Sbjct: 18  YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
                  ++ YW  G V C ++LALD +   +S+++L  IS DRY+ VT+ + Y +KRT 
Sbjct: 78  NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137

Query: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
           +     I A W++S ++  P       +V +    DG  Y Q   N    +   + I +F
Sbjct: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195

Query: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
           + P +IM ++Y  I R +K R +   +K+ PV   D  SP+   G               
Sbjct: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253

Query: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
           G      +NG     P     V+ +E  ++ +       A           E     + G
Sbjct: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313

Query: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
                 + ++     +++P         ++  V     +    + ++  RK+ +     A
Sbjct: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373

Query: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K       + T  +  ++  F++ W P+     +   C  A  +P  ++   +W+ Y 
Sbjct: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS++NP  Y + N  F+++FKH+L
Sbjct: 432 NSTINPACYALCNATFKKTFKHLL 455


>gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens]
          Length = 466

 Score =  137 bits (345), Expect = 2e-32
 Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           Y    V  +  V G L + T++GN+LV++++  +R L+   N FL SLA AD+++    M
Sbjct: 18  YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
                  ++ YW  G V C ++LALD +   +S+++L  IS DRY+ VT+ + Y +KRT 
Sbjct: 78  NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137

Query: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
           +     I A W++S ++  P       +V +    DG  Y Q   N    +   + I +F
Sbjct: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195

Query: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
           + P +IM ++Y  I R +K R +   +K+ PV   D  SP+   G               
Sbjct: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253

Query: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
           G      +NG     P     V+ +E  ++ +       A           E     + G
Sbjct: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313

Query: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
                 + ++     +++P         ++  V     +    + ++  RK+ +     A
Sbjct: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373

Query: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K       + T  +  ++  F++ W P+     +   C  A  +P  ++   +W+ Y 
Sbjct: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS++NP  Y + N  F+++FKH+L
Sbjct: 432 NSTINPACYALCNATFKKTFKHLL 455


>gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens]
          Length = 466

 Score =  137 bits (345), Expect = 2e-32
 Identities = 106/444 (23%), Positives = 195/444 (43%), Gaps = 43/444 (9%)

Query: 46  YSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVM 105
           Y    V  +  V G L + T++GN+LV++++  +R L+   N FL SLA AD+++    M
Sbjct: 18  YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSM 77

Query: 106 PFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTP 165
                  ++ YW  G V C ++LALD +   +S+++L  IS DRY+ VT+ + Y +KRT 
Sbjct: 78  NLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTT 137

Query: 166 RRVKATIVAVWLISAVISFPP------LVSLYRQPDGAAYPQCGLNDETWYILSSCIGSF 219
           +     I A W++S ++  P       +V +    DG  Y Q   N    +   + I +F
Sbjct: 138 KMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTF--GTAIAAF 195

Query: 220 FAPCLIMGLVYARIYRVAKLRTRTLSEKRAPV-GPDGASPTTENGL-------------- 264
           + P +IM ++Y  I R +K R +   +K+ PV   D  SP+   G               
Sbjct: 196 YLPVIIMTVLYWHISRASKSRIK--KDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDD 253

Query: 265 GAAAGAGENGHCAPPPAD---VEPDESSAAAERRRRRG-ALRRGGRRRAGAEGGAGGADG 320
           G      +NG     P     V+ +E  ++ +       A           E     + G
Sbjct: 254 GLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLG 313

Query: 321 QGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQ-----A 375
                 + ++     +++P         ++  V     +    + ++  RK+ +     A
Sbjct: 314 HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPA 373

Query: 376 REK-------RFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYC 428
           ++K       + T  +  ++  F++ W P+     +   C  A  +P  ++   +W+ Y 
Sbjct: 374 KKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFC--APCIPNTVWTIGYWLCYI 431

Query: 429 NSSLNPVIYTVFNQDFRRSFKHIL 452
           NS++NP  Y + N  F+++FKH+L
Sbjct: 432 NSTINPACYALCNATFKKTFKHLL 455


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,756,484
Number of Sequences: 37866
Number of extensions: 950925
Number of successful extensions: 17648
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 687
Number of HSP's successfully gapped in prelim test: 693
Number of HSP's that attempted gapping in prelim test: 11033
Number of HSP's gapped (non-prelim): 5519
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.