Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 70167113
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
(931 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 1880 0.0
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 1880 0.0
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 1817 0.0
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 1768 0.0
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 266 5e-71
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 253 8e-67
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 251 3e-66
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 250 5e-66
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 237 4e-62
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 136 8e-32
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 136 8e-32
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 126 8e-29
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 115 2e-25
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 105 3e-22
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 82 2e-15
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 68 5e-11
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 68 5e-11
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 68 5e-11
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 66 2e-10
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 63 1e-09
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 63 1e-09
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 63 1e-09
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 62 2e-09
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 62 2e-09
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 62 2e-09
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 62 3e-09
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 62 3e-09
gi|82659089 staufen isoform a [Homo sapiens] 56 1e-07
gi|82659087 staufen isoform b [Homo sapiens] 56 1e-07
gi|82659085 staufen isoform a [Homo sapiens] 56 1e-07
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 1880 bits (4869), Expect = 0.0
Identities = 931/931 (100%), Positives = 931/931 (100%)
Query: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL
Sbjct: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
Query: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP
Sbjct: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
Query: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA
Sbjct: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
Query: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF
Sbjct: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
Query: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK
Sbjct: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
Query: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ
Sbjct: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
Query: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK
Sbjct: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
Query: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH
Sbjct: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
Query: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL
Sbjct: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
Query: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK
Sbjct: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
Query: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV
Sbjct: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
Query: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES
Sbjct: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
Query: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH
Sbjct: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
Query: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD
Sbjct: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
Query: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA
Sbjct: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
Query: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 1880 bits (4869), Expect = 0.0
Identities = 931/931 (100%), Positives = 931/931 (100%)
Query: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL
Sbjct: 296 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 355
Query: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP
Sbjct: 356 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 415
Query: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA
Sbjct: 416 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 475
Query: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF
Sbjct: 476 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 535
Query: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK
Sbjct: 536 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 595
Query: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ
Sbjct: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
Query: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK
Sbjct: 656 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 715
Query: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH
Sbjct: 716 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 775
Query: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL
Sbjct: 776 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 835
Query: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK
Sbjct: 836 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 895
Query: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV
Sbjct: 896 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 955
Query: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES
Sbjct: 956 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 1015
Query: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH
Sbjct: 1016 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 1075
Query: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD
Sbjct: 1076 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 1135
Query: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA
Sbjct: 1136 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 1195
Query: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1196 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1226
Score = 33.1 bits (74), Expect = 1.2
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 18 SSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL---TDKKRERMQIKR-- 72
++A +L+ +G K ++IN VL + ++G + ++ TPP+W + T + + R
Sbjct: 156 TTAHDLSGKLGTPK-KEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPD 214
Query: 73 -NTNSVPETAPAAIPETKRN 91
++ P + P+ PE + +
Sbjct: 215 GHSQGAPNSDPSLEPEDRNS 234
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 1817 bits (4706), Expect = 0.0
Identities = 905/931 (97%), Positives = 905/931 (97%), Gaps = 26/931 (2%)
Query: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL
Sbjct: 296 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 355
Query: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP
Sbjct: 356 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 415
Query: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA
Sbjct: 416 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 475
Query: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF
Sbjct: 476 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 535
Query: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK
Sbjct: 536 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 595
Query: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ
Sbjct: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
Query: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK
Sbjct: 656 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 715
Query: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH
Sbjct: 716 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 775
Query: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
SKKQGKQEAADAALRVLIGENEKAERMGFTE LPL
Sbjct: 776 SKKQGKQEAADAALRVLIGENEKAERMGFTE--------------------------LPL 809
Query: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK
Sbjct: 810 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 869
Query: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV
Sbjct: 870 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 929
Query: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES
Sbjct: 930 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 989
Query: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH
Sbjct: 990 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 1049
Query: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD
Sbjct: 1050 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 1109
Query: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA
Sbjct: 1110 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 1169
Query: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1170 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1200
Score = 33.1 bits (74), Expect = 1.2
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 18 SSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL---TDKKRERMQIKR-- 72
++A +L+ +G K ++IN VL + ++G + ++ TPP+W + T + + R
Sbjct: 156 TTAHDLSGKLGTPK-KEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPD 214
Query: 73 -NTNSVPETAPAAIPETKRN 91
++ P + P+ PE + +
Sbjct: 215 GHSQGAPNSDPSLEPEDRNS 234
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 1768 bits (4579), Expect = 0.0
Identities = 886/931 (95%), Positives = 886/931 (95%), Gaps = 45/931 (4%)
Query: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL
Sbjct: 296 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 355
Query: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP
Sbjct: 356 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 415
Query: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA
Sbjct: 416 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 475
Query: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF
Sbjct: 476 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 535
Query: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK
Sbjct: 536 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 595
Query: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ
Sbjct: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
Query: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ VRK
Sbjct: 656 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ-------------------VRK 696
Query: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH
Sbjct: 697 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 756
Query: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
SKKQGKQEAADAALRVLIGENEKAERMGFTE LPL
Sbjct: 757 SKKQGKQEAADAALRVLIGENEKAERMGFTE--------------------------LPL 790
Query: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK
Sbjct: 791 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 850
Query: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV
Sbjct: 851 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 910
Query: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES
Sbjct: 911 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 970
Query: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH
Sbjct: 971 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 1030
Query: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD
Sbjct: 1031 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 1090
Query: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA
Sbjct: 1091 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 1150
Query: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1151 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1181
Score = 33.1 bits (74), Expect = 1.2
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 18 SSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL---TDKKRERMQIKR-- 72
++A +L+ +G K ++IN VL + ++G + ++ TPP+W + T + + R
Sbjct: 156 TTAHDLSGKLGTPK-KEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPD 214
Query: 73 -NTNSVPETAPAAIPETKRN 91
++ P + P+ PE + +
Sbjct: 215 GHSQGAPNSDPSLEPEDRNS 234
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 266 bits (681), Expect = 5e-71
Identities = 180/508 (35%), Positives = 264/508 (51%), Gaps = 79/508 (15%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 561
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 562 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 620
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 621 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 678
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIF- 457
Query: 679 KSCSDRAMESTESRHYPVFENPK--------QGKLRTKVENGEGTIPVESSDIVPTWDGI 730
S H P+ E P +G+LRTK+E+GEGTIPV S+ + TWDG+
Sbjct: 458 ------------SPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGV 505
Query: 731 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVT 790
GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 506 LQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI- 564
Query: 791 RDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGT 850
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 565 ---SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG- 617
Query: 851 VDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAKN 902
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 618 ----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKA 673
Query: 903 YFKKGLKDMGYGNWISKPQEEKNFYLCP 930
G G W+ KP E+ F L P
Sbjct: 674 RLFTAFIKAGLGAWVEKPTEQDQFSLTP 701
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 283
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 284 -------------------------------GKSE--------------ESSHYSTEKES 298
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 299 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 356
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 357 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 320 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 379
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 380 EAMKA 384
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.086
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
Score = 30.4 bits (67), Expect = 8.0
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
Query: 267 AMKAMTIL 274
A A+ +
Sbjct: 289 AQSALAAI 296
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 253 bits (645), Expect = 8e-67
Identities = 179/535 (33%), Positives = 269/535 (50%), Gaps = 93/535 (17%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 561
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 562 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 620
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 621 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 678
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIFS 458
Query: 679 ---------KSCSDRAME-----STESRHYPVFENPK---------------------QG 703
+S + ++ S + R + +P +G
Sbjct: 459 PHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARG 518
Query: 704 KLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQ 763
+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+LL+ F++
Sbjct: 519 QLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVE 578
Query: 764 PIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQS 823
PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S ++ RQ
Sbjct: 579 PIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISNAEA-RQP 632
Query: 824 GKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF-------KKLCSF 876
GK SVNW + D +E+++ T G ++EL R S+ L+ K+ S
Sbjct: 633 GKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRVHGKVPSH 686
Query: 877 RYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCP 930
R + + + Y E+K AA++Y+ AK G G W+ KP E+ F L P
Sbjct: 687 LLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 283
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 284 -------------------------------GKSE--------------ESSHYSTEKES 298
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 299 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 356
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 357 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 320 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 379
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 380 EAMKA 384
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.086
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
Score = 30.4 bits (67), Expect = 8.0
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
Query: 267 AMKAMTIL 274
A A+ +
Sbjct: 289 AQSALAAI 296
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 251 bits (640), Expect = 3e-66
Identities = 171/479 (35%), Positives = 253/479 (52%), Gaps = 79/479 (16%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 561
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 562 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 620
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 621 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 678
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIF- 457
Query: 679 KSCSDRAMESTESRHYPVFENPK--------QGKLRTKVENGEGTIPVESSDIVPTWDGI 730
S H P+ E P +G+LRTK+E+GEGTIPV S+ + TWDG+
Sbjct: 458 ------------SPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGV 505
Query: 731 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVT 790
GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 506 LQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI- 564
Query: 791 RDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGT 850
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 565 ---SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG- 617
Query: 851 VDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 901
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 618 ----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 672
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 283
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 284 -------------------------------GKSE--------------ESSHYSTEKES 298
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 299 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 356
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 357 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 320 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 379
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 380 EAMKA 384
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.086
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
Score = 30.4 bits (67), Expect = 8.0
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
Query: 267 AMKAMTIL 274
A A+ +
Sbjct: 289 AQSALAAI 296
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 250 bits (638), Expect = 5e-66
Identities = 169/472 (35%), Positives = 237/472 (50%), Gaps = 46/472 (9%)
Query: 463 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRR 522
FV V GR F SKK + +AA AAL+ L G TP+
Sbjct: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMP------ 358
Query: 523 TMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKD 582
F D I+ L + F +T P K LA I+M K
Sbjct: 359 --------------------QEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKG 398
Query: 583 SED-MGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAK 641
+ VV+L +G +C+ G+ LS +G VNDCHAE+++RR F+ FLY++L + S+ +
Sbjct: 399 LDARQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRRE 458
Query: 642 DS---IFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFE 698
DS IF K G ++++ + FHLY+ST+PCGD L S + + S+H
Sbjct: 459 DSERSIFVRLKEGG-YRLRENILFHLYVSTSPCGDARLH--SPYEITTDLHSSKH---LV 512
Query: 699 NPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALL 758
+G LRTK+E+GEGT+PV V TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL
Sbjct: 513 RKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALL 572
Query: 759 THFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYD 818
+HF++P+YL+S+ +G L GHL R + R+ G RH N P + VS +
Sbjct: 573 SHFVEPVYLQSIVVGSLHHTGHLARVMSHRMEGVGQ-LPASYRH----NRPLLSGVSDAE 627
Query: 819 SKRQSGKTKETSVNWCLADGYDLEILDGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSF 876
+ RQ GK+ S+NW + DLEI++ T G + GP V L+ +L +
Sbjct: 628 A-RQPGKSPPFSMNWVVGSA-DLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRLSTR 685
Query: 877 RYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYL 928
Y EAK A Y++ K K + G G W+ KP E++ F L
Sbjct: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQFLL 737
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 319 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 378
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
Query: 379 EEAMKA 384
E A+++
Sbjct: 183 ELALRS 188
Score = 35.8 bits (81), Expect = 0.19
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
Score = 33.9 bits (76), Expect = 0.72
Identities = 51/246 (20%), Positives = 88/246 (35%), Gaps = 59/246 (23%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 271
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
Query: 272 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 300
L +E A + + S+ Y + +
Sbjct: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
Query: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
Query: 361 TFPSVSAPSKKVAKQMAAEEAMKALH-----GEATNSMASDNQPEGMISESLDNLESMMP 415
TF S SKK+A+ AA+ A++ L G A P+ E D++ ++
Sbjct: 316 TFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQ----EFADSISQLVT 370
Query: 416 NKVRKI 421
K R++
Sbjct: 371 QKFREV 376
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 237 bits (604), Expect = 4e-62
Identities = 170/506 (33%), Positives = 258/506 (50%), Gaps = 93/506 (18%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 561
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 562 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 620
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 621 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 678
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIFS 458
Query: 679 ---------KSCSDRAME-----STESRHYPVFENPK---------------------QG 703
+S + ++ S + R + +P +G
Sbjct: 459 PHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARG 518
Query: 704 KLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQ 763
+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+LL+ F++
Sbjct: 519 QLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVE 578
Query: 764 PIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQS 823
PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S ++ RQ
Sbjct: 579 PIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISNAEA-RQP 632
Query: 824 GKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF-------KKLCSF 876
GK SVNW + D +E+++ T G ++EL R S+ L+ K+ S
Sbjct: 633 GKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRVHGKVPSH 686
Query: 877 RYRRDLLRLS-YGEAKKAARDYETAK 901
R + + + Y E+K AA++Y+ AK
Sbjct: 687 LLRSKITKPNVYHESKLAAKEYQAAK 712
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 283
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 284 -------------------------------GKSE--------------ESSHYSTEKES 298
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 299 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 356
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 357 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 320 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 379
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 380 EAMKA 384
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.086
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
Score = 30.4 bits (67), Expect = 8.0
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
Query: 267 AMKAMTIL 274
A A+ +
Sbjct: 289 AQSALAAI 296
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 136 bits (343), Expect = 8e-32
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 392 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 447
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 36 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 94
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 95 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 154
Query: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 566
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 155 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 208
Query: 567 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 626
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 209 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 265
Query: 627 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 683
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 266 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 318
Query: 684 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 743
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 319 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 369
Query: 744 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 800
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 370 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 425
Query: 801 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 854
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 426 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 484
Query: 855 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 914
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 485 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 544
Query: 915 NWISK 919
+WI K
Sbjct: 545 SWIVK 549
Score = 33.9 bits (76), Expect = 0.72
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 208 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 267
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
Query: 268 MKAMTILLE 276
A+ LL+
Sbjct: 138 KLALDELLQ 146
>gi|21245124 adenosine deaminase domain containing 1
(testis-specific) isoform 1 [Homo sapiens]
Length = 576
Score = 136 bits (343), Expect = 8e-32
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 392 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 447
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
Query: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 566
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 173 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
Query: 567 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 626
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 227 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 283
Query: 627 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 683
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 284 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 336
Query: 684 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 743
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 337 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 387
Query: 744 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 800
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 388 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 443
Query: 801 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 854
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 444 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 502
Query: 855 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 914
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 503 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 562
Query: 915 NWISK 919
+WI K
Sbjct: 563 SWIVK 567
Score = 33.9 bits (76), Expect = 0.72
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 208 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 267
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 268 MKAMTILLE 276
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 126 bits (317), Expect = 8e-29
Identities = 142/542 (26%), Positives = 236/542 (43%), Gaps = 53/542 (9%)
Query: 392 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 447
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
Query: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
Query: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 566
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 173 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
Query: 567 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 626
L LAA I+++ + VV++GTG D + G ++D HA + +RR
Sbjct: 227 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRS--- 280
Query: 627 FLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAM 686
L+ N + SIF L +K+ ++ LY++ P G + ++
Sbjct: 281 -----LLSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQ 328
Query: 687 ESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKIL 746
FE ++ L VE G I + + DG+ R+ +MS SDK+
Sbjct: 329 LRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLT 379
Query: 747 RWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHP 803
RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 380 RWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMF 435
Query: 804 FIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNE 857
++VN P + V + + + K S+NW D LEI+DG G + +
Sbjct: 436 YLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSM 494
Query: 858 LSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWI 917
SR+ K + F L + L +Y AK + Y+ AK K L+ GYG+WI
Sbjct: 495 ASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWI 554
Query: 918 SK 919
K
Sbjct: 555 VK 556
Score = 33.9 bits (76), Expect = 0.72
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 208 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 267
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 268 MKAMTILLE 276
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|223972690 adenosine deaminase domain containing 2 isoform 2
[Homo sapiens]
Length = 583
Score = 115 bits (288), Expect = 2e-25
Identities = 137/501 (27%), Positives = 210/501 (41%), Gaps = 60/501 (11%)
Query: 436 LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 495
L EYA S G F+ DQ P P F A++ G PA A+SK + KQ+AA +AL
Sbjct: 120 LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
Query: 496 VLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHR 555
+ + E E + P+ S+ + T + A L
Sbjct: 178 YIRSQLENPESPQTSSRPPLAPLSVENIL-------------------THEQRCAALVSA 218
Query: 556 CFNTLTNSFQPSLLGRKILAAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKG 608
F+ L + P + +A +I++++ +++ +V+LGTG+ C G L G
Sbjct: 219 GFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSG 277
Query: 609 ETVNDCHAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHL 664
+ ++DCH +I+RR +RFL+ +L+ + + + S+ P G G +K V HL
Sbjct: 278 QQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHL 337
Query: 665 YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 724
YIS P G + D + T P +P +L+ V + + +
Sbjct: 338 YISNTPKG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLC 387
Query: 725 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTR 783
T G +S SDK+ RW VLGL GALL H + P+Y S+ L L+R
Sbjct: 388 DTHVG--------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSR 439
Query: 784 AICCRVTRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDL 841
AI R D S L P++ H G + S+ + S+NW L D +
Sbjct: 440 AIHTRPCLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GI 496
Query: 842 EILDGTRGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYET 899
E++D G V + SR+ K + F + + LL L EA KA Y+
Sbjct: 497 EVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQE 555
Query: 900 AKNYFKKGLKDMGYGNWISKP 920
A+ L G G W SKP
Sbjct: 556 ARRQLSLLLDQQGLGAWPSKP 576
>gi|223972688 adenosine deaminase domain containing 2 isoform 1
[Homo sapiens]
Length = 665
Score = 105 bits (261), Expect = 3e-22
Identities = 129/495 (26%), Positives = 202/495 (40%), Gaps = 70/495 (14%)
Query: 452 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 511
V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E +
Sbjct: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
Query: 512 VTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 571
P+ S+ + T + A L F+ L + P +
Sbjct: 266 RPPLAPLSVENIL-------------------THEQRCAALVSAGFDLLLDERSPYWACK 306
Query: 572 KILAAIIMKKD-----------------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDC 614
+A +I+++ +++ +V+LGTG+ C G L G+ ++DC
Sbjct: 307 GTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDC 365
Query: 615 HAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAP 670
H +I+RR +RFL+ +L+ + + + S+ P G G +K V HLYIS P
Sbjct: 366 HGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTP 425
Query: 671 CGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGI 730
G + D + T P +P +L+ V + + + T G
Sbjct: 426 KG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG- 474
Query: 731 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRV 789
+S SDK+ RW VLGL GALL H + P+Y S+ L L+RAI R
Sbjct: 475 -------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRP 527
Query: 790 TRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGT 847
D S L P++ H G + S+ + S+NW L D +E++D
Sbjct: 528 CLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVA 584
Query: 848 RGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 905
G V + SR+ K + F + + LL L EA KA Y+ A+
Sbjct: 585 TGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLS 643
Query: 906 KGLKDMGYGNWISKP 920
L G G W SKP
Sbjct: 644 LLLDQQGLGAWPSKP 658
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 82.0 bits (201), Expect = 2e-15
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 37/221 (16%)
Query: 733 GERLRTMSCSDKILRWNVLGLQGALLTHFL-QPIYLKSVTLGYL-FSQGHLTRAICCRVT 790
G+R R+MSCSDK+ RWNVLG QGALL H L +PIYL +V +G +SQ + RA+ R
Sbjct: 291 GDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGR-C 349
Query: 791 RDGSAFEDGLRHPFIVNHPKVGRVS-IYDSKRQSGKTKE-----------TSVNWCLADG 838
++ SA G F V K+ + +++ R + + K +++W
Sbjct: 350 QNVSALPKG----FGVQELKILQSDLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPE 405
Query: 839 YDLEIL-----DGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRD----LLRL---- 885
L++ GT G S++SK +F F+KL S R RD LR+
Sbjct: 406 QPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLS-RIARDKWPHSLRVQKLD 464
Query: 886 SYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNF 926
+Y E K+AA Y+ A + +K + +G+WI P + F
Sbjct: 465 TYQEYKEAASSYQEAWSTLRKQV----FGSWIRNPPDYHQF 501
Score = 64.7 bits (156), Expect = 4e-10
Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 589 VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPA 648
+VS+GTG +C+ + G+ +ND HAE+I+RR F R+L +L + + +DSIF P
Sbjct: 61 IVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQL-QLAATLKEDSIFVPG 119
Query: 649 KGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFEN 699
++++ + F + S PCGD ++ +E + PVF N
Sbjct: 120 TQKGVWKLRRDLIFVFFSSHTPCGDASIIP------MLEFEDQPCCPVFRN 164
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 67.8 bits (164), Expect = 5e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 376
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 377 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 425
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 66 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 119
Query: 426 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 120 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 178
Query: 472 RWFPAVCAHSKKQGKQEAA 490
R+ SKK K+ AA
Sbjct: 179 RFIEIGSGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 267 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 318
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 319 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 365
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 366 SAPSKKVAKQMAAEEAMKALH 386
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 36.2 bits (82), Expect = 0.15
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 432 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 491
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 492 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 535
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 69 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 128
Query: 536 KTLP 539
P
Sbjct: 129 PVSP 132
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 67.8 bits (164), Expect = 5e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 376
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
Query: 377 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 425
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 87 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 140
Query: 426 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 141 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 199
Query: 472 RWFPAVCAHSKKQGKQEAA 490
R+ SKK K+ AA
Sbjct: 200 RFIEIGSGTSKKLAKRNAA 218
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
Query: 267 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 318
A A+ L LE A S S S + A + TP PS S
Sbjct: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
Query: 319 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 365
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
Query: 366 SAPSKKVAKQMAAEEAMKALH 386
S SKK+AK+ AA + + +H
Sbjct: 206 SGTSKKLAKRNAAAKMLLRVH 226
Score = 36.2 bits (82), Expect = 0.15
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 432 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 491
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
Query: 492 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 535
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 90 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 149
Query: 536 KTLP 539
P
Sbjct: 150 PVSP 153
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 67.8 bits (164), Expect = 5e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 376
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 377 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 425
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 66 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 119
Query: 426 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 120 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 178
Query: 472 RWFPAVCAHSKKQGKQEAA 490
R+ SKK K+ AA
Sbjct: 179 RFIEIGSGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 267 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 318
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 319 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 365
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 366 SAPSKKVAKQMAAEEAMKALH 386
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 36.2 bits (82), Expect = 0.15
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 432 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 491
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 492 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 535
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 69 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 128
Query: 536 KTLP 539
P
Sbjct: 129 PVSP 132
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 65.9 bits (159), Expect = 2e-10
Identities = 58/201 (28%), Positives = 96/201 (47%), Gaps = 30/201 (14%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 271
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
Query: 272 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 325
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
Query: 326 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
Query: 386 HGEATNSMASDNQPEGMISES 406
+ A++N+ + +I ++
Sbjct: 575 F---SGPNAANNKKKKIIPQA 592
Score = 61.6 bits (148), Expect = 3e-09
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 24/187 (12%)
Query: 328 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHG 387
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+ G
Sbjct: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAM-G 452
Query: 388 EATNSMA----------SDNQP--EGMISESLDN-----LESMMPNKVRKIGELVRYLNT 430
T A SDN+ E + S S +N E+ +VR G ++
Sbjct: 453 YPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK 512
Query: 431 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 490
NPV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 513 NPVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAA 567
Query: 491 DAALRVL 497
AAL L
Sbjct: 568 LAALEKL 574
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 282
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 283 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 324
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 325 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 384
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 385 L 385
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 287 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 346
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 347 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 400
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 401 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 450
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 451 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 504
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 282
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 283 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 324
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 325 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 384
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 385 L 385
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 287 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 346
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 347 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 400
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 401 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 450
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 451 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 504
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 282
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 283 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 324
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 325 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 384
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 385 L 385
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 287 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 346
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 347 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 400
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 401 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 450
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 451 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 504
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 216 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 275
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 276 EEAKA 280
+E KA
Sbjct: 77 KEKKA 81
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 439 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 499 GENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTL 538
E + + T G S+ + L++R AQ K L
Sbjct: 77 KEKKAVSPLLLTTTNSSEGLSMGNYIGLINRI--AQKKRL 114
Score = 40.4 bits (93), Expect = 0.008
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 330 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 388
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 389 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 445
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 446 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 500
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 216 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 275
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 276 EEAKA 280
+E KA
Sbjct: 77 KEKKA 81
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 439 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 499 GENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTL 538
E + + T G S+ + L++R AQ K L
Sbjct: 77 KEKKAVSPLLLTTTNSSEGLSMGNYIGLINRI--AQKKRL 114
Score = 40.4 bits (93), Expect = 0.008
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 330 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 388
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 389 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 445
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 446 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 500
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 216 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 275
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 276 EEAKA 280
+E KA
Sbjct: 77 KEKKA 81
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 439 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 499 GENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTL 538
E + + T G S+ + L++R AQ K L
Sbjct: 77 KEKKAVSPLLLTTTNSSEGLSMGNYIGLINRI--AQKKRL 114
Score = 40.4 bits (93), Expect = 0.008
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 330 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 388
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 389 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 445
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 446 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 500
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 61.6 bits (148), Expect = 3e-09
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 21/179 (11%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 282
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 283 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 326
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 327 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKL 592
Score = 57.4 bits (137), Expect = 6e-08
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 37/238 (15%)
Query: 287 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 346
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 347 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 400
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 401 ---------GMISESLDNLESMMPN-----KVRKIGELVRYLNTNPVGGLLEYARSHGFA 446
+ E++ + P+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 447 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 504
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 61.6 bits (148), Expect = 3e-09
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 21/179 (11%)
Query: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 282
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 283 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 326
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 327 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKL 592
Score = 57.4 bits (137), Expect = 6e-08
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 37/238 (15%)
Query: 287 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 346
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 347 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 400
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 401 ---------GMISESLDNLESMMPN-----KVRKIGELVRYLNTNPVGGLLEYARSHGFA 446
+ E++ + P+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 447 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 504
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 56.2 bits (134), Expect = 1e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
Query: 267 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 326
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
Query: 327 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
Score = 44.7 bits (104), Expect = 4e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 240 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 299
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
Query: 300 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 359
KS ++ + E K F + + GP H F V+VG
Sbjct: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
Query: 360 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 419
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
Query: 420 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 472 RWFPAVCAHSKKQGKQEAADAALRVL 497
+KK K+ AA+ L +L
Sbjct: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
Score = 39.7 bits (91), Expect = 0.013
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 365
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
Query: 366 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 425
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
Query: 426 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 485
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
Query: 486 KQEAADAALRVL 497
K+ AA A L L
Sbjct: 157 KKNAAIAVLEEL 168
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 56.2 bits (134), Expect = 1e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
Query: 267 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 326
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
Query: 327 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
Score = 44.7 bits (104), Expect = 4e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 240 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 299
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
Query: 300 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 359
KS ++ + E K F + + GP H F V+VG
Sbjct: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
Query: 360 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 419
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 224 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 267
Query: 420 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 268 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
Query: 472 RWFPAVCAHSKKQGKQEAADAALRVL 497
+KK K+ AA+ L +L
Sbjct: 328 HTAEGT-GTNKKVAKRNAAENMLEIL 352
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 40/209 (19%)
Query: 302 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 354
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
Query: 355 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLD 408
++VG Q F +++ AK AA +A++ L E PE + ++
Sbjct: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVN 172
Query: 409 NLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 468
ES N LN + + + E A F++ +SGPPH FV +
Sbjct: 173 GRESEEEN-----------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
Query: 469 VGGRWFPAVCAHSKKQGKQEAADAALRVL 497
V G + SKK K+ AA A L L
Sbjct: 222 V-GEFVGEGEGKSKKISKKNAAIAVLEEL 249
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 56.2 bits (134), Expect = 1e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
Query: 267 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 326
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
Query: 327 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
Score = 44.7 bits (104), Expect = 4e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 240 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 299
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
Query: 300 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 359
KS ++ + E K F + + GP H F V+VG
Sbjct: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
Query: 360 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 419
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
Query: 420 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 472 RWFPAVCAHSKKQGKQEAADAALRVL 497
+KK K+ AA+ L +L
Sbjct: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
Score = 39.7 bits (91), Expect = 0.013
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 365
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
Query: 366 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 425
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
Query: 426 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 485
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
Query: 486 KQEAADAALRVL 497
K+ AA A L L
Sbjct: 157 KKNAAIAVLEEL 168
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,311,146
Number of Sequences: 37866
Number of extensions: 1666699
Number of successful extensions: 5350
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 5091
Number of HSP's gapped (non-prelim): 221
length of query: 931
length of database: 18,247,518
effective HSP length: 112
effective length of query: 819
effective length of database: 14,006,526
effective search space: 11471344794
effective search space used: 11471344794
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.