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Search of human proteins with 70167032
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
(1181 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 2394 0.0
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 2382 0.0
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 2368 0.0
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 1768 0.0
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 266 7e-71
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 257 4e-68
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 253 1e-66
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 251 4e-66
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 237 6e-62
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 132 3e-30
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 132 3e-30
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 122 3e-27
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 119 2e-26
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 108 2e-23
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 82 3e-15
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 69 3e-11
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 64 8e-10
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 64 8e-10
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 64 8e-10
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 62 2e-09
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 62 2e-09
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 62 2e-09
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 62 2e-09
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 62 2e-09
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 60 2e-08
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 60 2e-08
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 60 2e-08
gi|7657625 staufen homolog 2 [Homo sapiens] 58 6e-08
gi|82659089 staufen isoform a [Homo sapiens] 56 2e-07
gi|82659087 staufen isoform b [Homo sapiens] 56 2e-07
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 2394 bits (6203), Expect = 0.0
Identities = 1181/1181 (100%), Positives = 1181/1181 (100%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHG 720
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHG
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHG 720
Query: 721 FAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 780
FAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA
Sbjct: 721 FAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 780
Query: 781 ERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVV 840
ERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVV
Sbjct: 781 ERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVV 840
Query: 841 SLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKG 900
SLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKG
Sbjct: 841 SLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKG 900
Query: 901 GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVE 960
GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVE
Sbjct: 901 GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVE 960
Query: 961 NGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSV 1020
NGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSV
Sbjct: 961 NGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSV 1020
Query: 1021 TLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETS 1080
TLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETS
Sbjct: 1021 TLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETS 1080
Query: 1081 VNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEA 1140
VNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEA
Sbjct: 1081 VNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEA 1140
Query: 1141 KKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1181
KKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1141 KKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1181
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 2382 bits (6173), Expect = 0.0
Identities = 1181/1200 (98%), Positives = 1181/1200 (98%), Gaps = 19/1200 (1%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ-------------------VRKIGELV 701
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ VRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 702 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 761
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 762 KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 821
KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR
Sbjct: 781 KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 840
Query: 822 KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE 881
KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE
Sbjct: 841 KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE 900
Query: 882 LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES 941
LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES
Sbjct: 901 LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES 960
Query: 942 RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL 1001
RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL
Sbjct: 961 RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL 1020
Query: 1002 GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV 1061
GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV
Sbjct: 1021 GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV 1080
Query: 1062 GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK 1121
GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK
Sbjct: 1081 GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK 1140
Query: 1122 KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1181
KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1141 KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1200
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 2368 bits (6136), Expect = 0.0
Identities = 1181/1226 (96%), Positives = 1181/1226 (96%), Gaps = 45/1226 (3%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ-------------------VRKIGELV 701
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ VRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 702 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 761
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 762 KQEAADAALRVLIGENEKAERMGFTE--------------------------LPLTGSTF 795
KQEAADAALRVLIGENEKAERMGFTE LPLTGSTF
Sbjct: 781 KQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF 840
Query: 796 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 855
HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS
Sbjct: 841 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 900
Query: 856 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 915
LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY
Sbjct: 901 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 960
Query: 916 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 975
ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP
Sbjct: 961 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 1020
Query: 976 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1035
TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI
Sbjct: 1021 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1080
Query: 1036 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1095
CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD
Sbjct: 1081 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1140
Query: 1096 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1155
GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK
Sbjct: 1141 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200
Query: 1156 KGLKDMGYGNWISKPQEEKNFYLCPV 1181
KGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1201 KGLKDMGYGNWISKPQEEKNFYLCPV 1226
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 1768 bits (4579), Expect = 0.0
Identities = 886/931 (95%), Positives = 886/931 (95%), Gaps = 45/931 (4%)
Query: 296 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 355
MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL
Sbjct: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
Query: 356 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 415
TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP
Sbjct: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
Query: 416 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 475
VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA
Sbjct: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
Query: 476 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 535
IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF
Sbjct: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
Query: 536 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 595
KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK
Sbjct: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
Query: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ
Sbjct: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
Query: 656 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ-------------------VRK 696
TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ VRK
Sbjct: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
Query: 697 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 756
IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH
Sbjct: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
Query: 757 SKKQGKQEAADAALRVLIGENEKAERMGFTE--------------------------LPL 790
SKKQGKQEAADAALRVLIGENEKAERMGFTE LPL
Sbjct: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
Query: 791 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 850
TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK
Sbjct: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
Query: 851 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 910
GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV
Sbjct: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
Query: 911 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 970
SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES
Sbjct: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
Query: 971 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 1030
SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH
Sbjct: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
Query: 1031 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 1090
LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD
Sbjct: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
Query: 1091 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 1150
LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA
Sbjct: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
Query: 1151 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1181
KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
Score = 33.1 bits (74), Expect = 1.6
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 156 TTAHDLSGKLGTPK-KEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPD 214
++A +L+ +G K ++IN VL + ++G + ++ TPP+W + T + + R
Sbjct: 18 SSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL---TDKKRERMQIKR-- 72
Query: 215 GHSQGAPNSDPSLEPEDRNS 234
++ P + P+ PE + +
Sbjct: 73 -NTNSVPETAPAAIPETKRN 91
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 266 bits (681), Expect = 7e-71
Identities = 175/482 (36%), Positives = 259/482 (53%), Gaps = 53/482 (10%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 783
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 784 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 837
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 838 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 894
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 895 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPK--- 951
F+ ++ G ++K+ V FHLYIST+PCGD +F S H P+ E P
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIF-------------SPHEPILEEPADRH 471
Query: 952 -----QGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGA 1006
+G+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+
Sbjct: 472 PNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGS 531
Query: 1007 LLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSI 1066
LL+ F++PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S
Sbjct: 532 LLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISN 586
Query: 1067 YDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF------ 1120
++ RQ GK SVNW + D +E+++ T G ++EL R S+ L+
Sbjct: 587 AEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRV 639
Query: 1121 -KKLCSFRYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYL 1178
K+ S R + + + Y E+K AA++Y+ AK G G W+ KP E+ F L
Sbjct: 640 HGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSL 699
Query: 1179 CP 1180
P
Sbjct: 700 TP 701
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 257 bits (657), Expect = 4e-68
Identities = 167/446 (37%), Positives = 234/446 (52%), Gaps = 20/446 (4%)
Query: 739 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQ 798
FV V GR F SKK + +AA AAL+ L G F D
Sbjct: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADS 364
Query: 799 IAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSED-MGVVVSLGTGNRCVKGDSLSLK 857
I+ L + F +T P K LA I+M K + VV+L +G +C+ G+ LS +
Sbjct: 365 ISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEHLSDQ 424
Query: 858 GETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDS---IFEPAKGGEKLQIKKTVSFHL 914
G VNDCHAE+++RR F+ FLY++L + S+ +DS IF K G ++++ + FHL
Sbjct: 425 GLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGG-YRLRENILFHL 483
Query: 915 YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 974
Y+ST+PCGD L S + + S+H +G LRTK+E+GEGT+PV V
Sbjct: 484 YVSTSPCGDARLH--SPYEITTDLHSSKH---LVRKFRGHLRTKIESGEGTVPVRGPSAV 538
Query: 975 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRA 1034
TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL+HF++P+YL+S+ +G L GHL R
Sbjct: 539 QTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARV 598
Query: 1035 ICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEIL 1094
+ R+ G RH N P + VS ++ RQ GK+ S+NW + DLEI+
Sbjct: 599 MSHRMEGVGQ-LPASYRH----NRPLLSGVSDAEA-RQPGKSPPFSMNWVVGSA-DLEII 651
Query: 1095 DGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKN 1152
+ T G + GP V L+ +L + Y EAK A Y++ K
Sbjct: 652 NATTGRRSCGGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQ 711
Query: 1153 YFKKGLKDMGYGNWISKPQEEKNFYL 1178
K + G G W+ KP E++ F L
Sbjct: 712 QLFKAFQKAGLGTWVRKPPEQQQFLL 737
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 614 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 673
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
Query: 674 EEAMKA 679
E A+++
Sbjct: 183 ELALRS 188
Score = 35.8 bits (81), Expect = 0.25
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
Score = 32.0 bits (71), Expect = 3.6
Identities = 44/205 (21%), Positives = 74/205 (36%), Gaps = 50/205 (24%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
Query: 567 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 595
L +E A + + S+ Y + +
Sbjct: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
Query: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
Query: 656 TFPSVSAPSKKVAKQMAAEEAMKAL 680
TF S SKK+A+ AA+ A++ L
Sbjct: 316 TFEG-SGRSKKLARGQAAQAALQEL 339
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 253 bits (645), Expect = 1e-66
Identities = 174/509 (34%), Positives = 264/509 (51%), Gaps = 67/509 (13%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 783
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 784 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 837
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 838 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 894
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 895 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD---------KSCSDRAME-----STE 940
F+ ++ G ++K+ V FHLYIST+PCGD +F +S + ++ S +
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQ 484
Query: 941 SRHYPVFENPK---------------------QGKLRTKVENGEGTIPVESSDIVPTWDG 979
R + +P +G+LRTK+E+GEGTIPV S+ + TWDG
Sbjct: 485 PRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDG 544
Query: 980 IRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRV 1039
+ GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 545 VLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI 604
Query: 1040 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1099
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 605 ----SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG 657
Query: 1100 TVDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1151
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 658 -----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
Query: 1152 NYFKKGLKDMGYGNWISKPQEEKNFYLCP 1180
G G W+ KP E+ F L P
Sbjct: 713 ARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 251 bits (640), Expect = 4e-66
Identities = 166/453 (36%), Positives = 248/453 (54%), Gaps = 53/453 (11%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 783
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 784 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 837
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 838 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 894
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 895 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPK--- 951
F+ ++ G ++K+ V FHLYIST+PCGD +F S H P+ E P
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIF-------------SPHEPILEEPADRH 471
Query: 952 -----QGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGA 1006
+G+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+
Sbjct: 472 PNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGS 531
Query: 1007 LLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSI 1066
LL+ F++PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S
Sbjct: 532 LLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISN 586
Query: 1067 YDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF------ 1120
++ RQ GK SVNW + D +E+++ T G ++EL R S+ L+
Sbjct: 587 AEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRV 639
Query: 1121 -KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1151
K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 640 HGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 672
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 237 bits (604), Expect = 6e-62
Identities = 165/480 (34%), Positives = 253/480 (52%), Gaps = 67/480 (13%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 783
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 784 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 837
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 838 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 894
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 895 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD---------KSCSDRAME-----STE 940
F+ ++ G ++K+ V FHLYIST+PCGD +F +S + ++ S +
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQ 484
Query: 941 SRHYPVFENPK---------------------QGKLRTKVENGEGTIPVESSDIVPTWDG 979
R + +P +G+LRTK+E+GEGTIPV S+ + TWDG
Sbjct: 485 PRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDG 544
Query: 980 IRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRV 1039
+ GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 545 VLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI 604
Query: 1040 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1099
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 605 ----SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG 657
Query: 1100 TVDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1151
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 658 -----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 132 bits (331), Expect = 3e-30
Identities = 131/496 (26%), Positives = 215/496 (43%), Gaps = 57/496 (11%)
Query: 707 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 766
NPV L ++A+ + K +G P F + A V G + +KK+ + AA
Sbjct: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
Query: 767 DAALRVLIGENEK--------------AERMGFTELPLTGSTFHD-------QIAMLSHR 805
AL L+ +E AE + +EL ++ +I+ +
Sbjct: 138 KLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKE 197
Query: 806 CFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCH 865
FN L ++ L LAA I+++ + VV++GTG D + G ++D H
Sbjct: 198 RFNQLISNRSEYLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTH 254
Query: 866 AEIISRRGFIRFLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCG 922
A + +RR +R+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G
Sbjct: 255 AVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKG 314
Query: 923 DGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRL 982
+ ++ FE ++ L VE G I + + DG+
Sbjct: 315 SAQI-------KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN- 360
Query: 983 GERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV- 1039
R+ +MS SDK+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + +
Sbjct: 361 --RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIK 414
Query: 1040 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1099
R A L ++VN P + V + + + K S+NW D LEI+DG G
Sbjct: 415 QRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSG 473
Query: 1100 TV------DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNY 1153
+ + SR+ K + F L + L +Y AK + Y+ AK
Sbjct: 474 KITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCK 533
Query: 1154 FKKGLKDMGYGNWISK 1169
K L+ GYG+WI K
Sbjct: 534 LKSYLQQHGYGSWIVK 549
Score = 33.9 bits (76), Expect = 0.94
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 138 KLALDELLQ 146
>gi|21245124 adenosine deaminase domain containing 1 (testis-specific)
isoform 1 [Homo sapiens]
Length = 576
Score = 132 bits (331), Expect = 3e-30
Identities = 131/496 (26%), Positives = 215/496 (43%), Gaps = 57/496 (11%)
Query: 707 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 766
NPV L ++A+ + K +G P F + A V G + +KK+ + AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 767 DAALRVLIGENEK--------------AERMGFTELPLTGSTFHD-------QIAMLSHR 805
AL L+ +E AE + +EL ++ +I+ +
Sbjct: 156 KLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKE 215
Query: 806 CFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCH 865
FN L ++ L LAA I+++ + VV++GTG D + G ++D H
Sbjct: 216 RFNQLISNRSEYLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTH 272
Query: 866 AEIISRRGFIRFLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCG 922
A + +RR +R+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G
Sbjct: 273 AVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKG 332
Query: 923 DGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRL 982
+ ++ FE ++ L VE G I + + DG+
Sbjct: 333 SAQI-------KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN- 378
Query: 983 GERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV- 1039
R+ +MS SDK+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + +
Sbjct: 379 --RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIK 432
Query: 1040 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1099
R A L ++VN P + V + + + K S+NW D LEI+DG G
Sbjct: 433 QRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSG 491
Query: 1100 TV------DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNY 1153
+ + SR+ K + F L + L +Y AK + Y+ AK
Sbjct: 492 KITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCK 551
Query: 1154 FKKGLKDMGYGNWISK 1169
K L+ GYG+WI K
Sbjct: 552 LKSYLQQHGYGSWIVK 567
Score = 33.9 bits (76), Expect = 0.94
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 122 bits (305), Expect = 3e-27
Identities = 129/493 (26%), Positives = 208/493 (42%), Gaps = 62/493 (12%)
Query: 707 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 766
NPV L ++A+ + K +G P F + A V G + +KK+ + AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 767 DAALRVLIGENEK--------------AERMGFTELPLTGSTFHD-------QIAMLSHR 805
AL L+ +E AE + +EL ++ +I+ +
Sbjct: 156 KLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKE 215
Query: 806 CFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCH 865
FN L ++ L LAA I+++ + VV++GTG D + G ++D H
Sbjct: 216 RFNQLISNRSEYLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTH 272
Query: 866 AEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGA 925
A + +RR L+ N + SIF L +K+ ++ LY++ P G
Sbjct: 273 AVVTARRS--------LLSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQ 324
Query: 926 LFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGER 985
+ ++ FE ++ L VE G I + + DG+ R
Sbjct: 325 I-------KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---R 368
Query: 986 LRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRD 1042
+ +MS SDK+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R
Sbjct: 369 ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRV 424
Query: 1043 GSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV- 1101
A L ++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 425 DDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKIT 483
Query: 1102 -----DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKK 1156
+ SR+ K + F L + L +Y AK + Y+ AK K
Sbjct: 484 ESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKS 543
Query: 1157 GLKDMGYGNWISK 1169
L+ GYG+WI K
Sbjct: 544 YLQQHGYGSWIVK 556
Score = 33.9 bits (76), Expect = 0.94
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|223972690 adenosine deaminase domain containing 2 isoform 2 [Homo
sapiens]
Length = 583
Score = 119 bits (298), Expect = 2e-26
Identities = 136/482 (28%), Positives = 206/482 (42%), Gaps = 48/482 (9%)
Query: 712 LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 771
L EYA S G F+ DQ P P F A++ G PA A+SK + KQ+AA +AL
Sbjct: 120 LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
Query: 772 VLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKIL 824
+ + E E + P + I RC F+ L + P + +
Sbjct: 178 YIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTV 237
Query: 825 AAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRF 877
A +I++++ +++ +V+LGTG+ C G L G+ ++DCH +I+RR +RF
Sbjct: 238 AGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRF 296
Query: 878 LYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 933
L+ +L+ + + + S+ P G G +K V HLYIS P G + D
Sbjct: 297 LFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARD 349
Query: 934 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 993
+ T P +P +L+ V + + + T G +S SD
Sbjct: 350 IYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASD 398
Query: 994 KILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRH 1052
K+ RW VLGL GALL H + P+Y S+ L L+RAI R D S L
Sbjct: 399 KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPP 457
Query: 1053 PFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNEL 1108
P++ H G + S+ + S+NW L D +E++D G V +
Sbjct: 458 PYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPP 515
Query: 1109 SRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWIS 1168
SR+ K + F + + LL L EA KA Y+ A+ L G G W S
Sbjct: 516 SRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPS 574
Query: 1169 KP 1170
KP
Sbjct: 575 KP 576
>gi|223972688 adenosine deaminase domain containing 2 isoform 1 [Homo
sapiens]
Length = 665
Score = 108 bits (271), Expect = 2e-23
Identities = 128/476 (26%), Positives = 198/476 (41%), Gaps = 58/476 (12%)
Query: 728 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 787
V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E +
Sbjct: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
Query: 788 LPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKILAAIIMKKD-------- 832
P + I RC F+ L + P + +A +I+++
Sbjct: 266 RPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSC 325
Query: 833 ---------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELM 883
+++ +V+LGTG+ C G L G+ ++DCH +I+RR +RFL+ +L+
Sbjct: 326 TEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLL 384
Query: 884 ---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 939
+ + + S+ P G G +K V HLYIS P G + D + T
Sbjct: 385 LATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARDIYLPPT 437
Query: 940 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 999
P +P +L+ V + + + T G +S SDK+ RW
Sbjct: 438 SEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASDKLARWA 486
Query: 1000 VLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRHPFI--V 1056
VLGL GALL H + P+Y S+ L L+RAI R D S L P++
Sbjct: 487 VLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPPPYVRTA 545
Query: 1057 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNELSRVSKK 1114
H G + S+ + S+NW L D +E++D G V + SR+ K
Sbjct: 546 LHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPPSRLCKA 603
Query: 1115 NIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKP 1170
+ F + + LL L EA KA Y+ A+ L G G W SKP
Sbjct: 604 SFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPSKP 658
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 82.0 bits (201), Expect = 3e-15
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 37/221 (16%)
Query: 983 GERLRTMSCSDKILRWNVLGLQGALLTHFL-QPIYLKSVTLGYL-FSQGHLTRAICCRVT 1040
G+R R+MSCSDK+ RWNVLG QGALL H L +PIYL +V +G +SQ + RA+ R
Sbjct: 291 GDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGR-C 349
Query: 1041 RDGSAFEDGLRHPFIVNHPKVGRVS-IYDSKRQSGKTKE-----------TSVNWCLADG 1088
++ SA G F V K+ + +++ R + + K +++W
Sbjct: 350 QNVSALPKG----FGVQELKILQSDLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPE 405
Query: 1089 YDLEIL-----DGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRD----LLRL---- 1135
L++ GT G S++SK +F F+KL S R RD LR+
Sbjct: 406 QPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLS-RIARDKWPHSLRVQKLD 464
Query: 1136 SYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNF 1176
+Y E K+AA Y+ A + +K + +G+WI P + F
Sbjct: 465 TYQEYKEAASSYQEAWSTLRKQV----FGSWIRNPPDYHQF 501
Score = 64.7 bits (156), Expect = 5e-10
Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 839 VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPA 898
+VS+GTG +C+ + G+ +ND HAE+I+RR F R+L +L + + +DSIF P
Sbjct: 61 IVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQL-QLAATLKEDSIFVPG 119
Query: 899 KGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFEN 949
++++ + F + S PCGD ++ +E + PVF N
Sbjct: 120 TQKGVWKLRRDLIFVFFSSHTPCGDASIIP------MLEFEDQPCCPVFRN 164
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 68.9 bits (167), Expect = 3e-11
Identities = 62/220 (28%), Positives = 101/220 (45%), Gaps = 30/220 (13%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
Query: 567 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 620
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
Query: 621 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
Query: 681 HGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHG 720
+ A++N+ +KI + + V ++ R G
Sbjct: 575 F---SGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRG 611
Score = 57.4 bits (137), Expect = 8e-08
Identities = 49/186 (26%), Positives = 79/186 (42%), Gaps = 41/186 (22%)
Query: 623 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL-- 680
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+
Sbjct: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGY 453
Query: 681 ---------------------------------HGEATNSMASDNQVRKIGELVRYLNTN 707
G +T +S +VR G ++ N
Sbjct: 454 PTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKN 513
Query: 708 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 767
PV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 514 PVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAAL 568
Query: 768 AALRVL 773
AAL L
Sbjct: 569 AALEKL 574
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 63.9 bits (154), Expect = 8e-10
Identities = 56/196 (28%), Positives = 90/196 (45%), Gaps = 29/196 (14%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 LHGEATNSMASDNQVR 695
L + ++ ++ + R
Sbjct: 588 LFPDTPLALDANKKKR 603
Score = 48.5 bits (114), Expect = 4e-05
Identities = 53/234 (22%), Positives = 90/234 (38%), Gaps = 52/234 (22%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQVRKI 697
H P F V V +F S PSKK AK A + ++ + E +S ++ +
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 698 -------------------------------GELVRYLNTNPVGGLLEYARSHGFAAEFK 726
G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 727 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 780
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 63.9 bits (154), Expect = 8e-10
Identities = 56/196 (28%), Positives = 90/196 (45%), Gaps = 29/196 (14%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 LHGEATNSMASDNQVR 695
L + ++ ++ + R
Sbjct: 588 LFPDTPLALDANKKKR 603
Score = 48.5 bits (114), Expect = 4e-05
Identities = 53/234 (22%), Positives = 90/234 (38%), Gaps = 52/234 (22%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQVRKI 697
H P F V V +F S PSKK AK A + ++ + E +S ++ +
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 698 -------------------------------GELVRYLNTNPVGGLLEYARSHGFAAEFK 726
G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 727 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 780
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 63.9 bits (154), Expect = 8e-10
Identities = 56/196 (28%), Positives = 90/196 (45%), Gaps = 29/196 (14%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 LHGEATNSMASDNQVR 695
L + ++ ++ + R
Sbjct: 588 LFPDTPLALDANKKKR 603
Score = 48.5 bits (114), Expect = 4e-05
Identities = 53/234 (22%), Positives = 90/234 (38%), Gaps = 52/234 (22%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQVRKI 697
H P F V V +F S PSKK AK A + ++ + E +S ++ +
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 698 -------------------------------GELVRYLNTNPVGGLLEYARSHGFAAEFK 726
G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 727 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 780
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 715 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEIL- 75
Query: 775 GENEKAERMGFTELPLTGSTFHDQIAM 801
E+ + L LT + + ++M
Sbjct: 76 ----NKEKKAVSPLLLTTTNSSEGLSM 98
Score = 42.4 bits (98), Expect = 0.003
Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 3/152 (1%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEA 684
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKE- 78
Query: 685 TNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 744
S + N +G + A+ ++ SG F Y+ K
Sbjct: 79 -KKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQC-ASGVHGPEGFHYKCK 136
Query: 745 VGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 776
+G + + +K++ KQ AA A ++ E
Sbjct: 137 MGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 715 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEIL- 75
Query: 775 GENEKAERMGFTELPLTGSTFHDQIAM 801
E+ + L LT + + ++M
Sbjct: 76 ----NKEKKAVSPLLLTTTNSSEGLSM 98
Score = 42.4 bits (98), Expect = 0.003
Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 3/152 (1%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEA 684
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKE- 78
Query: 685 TNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 744
S + N +G + A+ ++ SG F Y+ K
Sbjct: 79 -KKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQC-ASGVHGPEGFHYKCK 136
Query: 745 VGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 776
+G + + +K++ KQ AA A ++ E
Sbjct: 137 MGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 715 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEIL- 75
Query: 775 GENEKAERMGFTELPLTGSTFHDQIAM 801
E+ + L LT + + ++M
Sbjct: 76 ----NKEKKAVSPLLLTTTNSSEGLSM 98
Score = 42.4 bits (98), Expect = 0.003
Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 3/152 (1%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEA 684
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKE- 78
Query: 685 TNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 744
S + N +G + A+ ++ SG F Y+ K
Sbjct: 79 -KKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQC-ASGVHGPEGFHYKCK 136
Query: 745 VGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 776
+G + + +K++ KQ AA A ++ E
Sbjct: 137 MGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 62.4 bits (150), Expect = 2e-09
Identities = 50/194 (25%), Positives = 92/194 (47%), Gaps = 21/194 (10%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 621
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 622 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALH 681
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKLF 593
Query: 682 GEATNSMASDNQVR 695
+ ++ ++ + R
Sbjct: 594 PDTPLALDANKKKR 607
Score = 50.8 bits (120), Expect = 7e-06
Identities = 57/238 (23%), Positives = 93/238 (39%), Gaps = 56/238 (23%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL------------HGE------ 683
H P F V V +F S PSKK AK A + ++ + GE
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 684 ---------------------ATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHGFA 722
A S A+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 723 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 780
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 62.4 bits (150), Expect = 2e-09
Identities = 50/194 (25%), Positives = 92/194 (47%), Gaps = 21/194 (10%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 621
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 622 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALH 681
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKLF 593
Query: 682 GEATNSMASDNQVR 695
+ ++ ++ + R
Sbjct: 594 PDTPLALDANKKKR 607
Score = 50.8 bits (120), Expect = 7e-06
Identities = 57/238 (23%), Positives = 93/238 (39%), Gaps = 56/238 (23%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL------------HGE------ 683
H P F V V +F S PSKK AK A + ++ + GE
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 684 ---------------------ATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHGFA 722
A S A+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 723 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 780
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 59.7 bits (143), Expect = 2e-08
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 40/193 (20%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 672 AAEEAMKALHGEA---------------TNSMASDNQVRKIGELV--------------- 701
AAE A+K L G + +S+ D V
Sbjct: 66 AAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPME 125
Query: 702 -------RYLNTNPVGGLLEYARSHGF-AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAV 753
+ NPVG L E G+ E+ + +SGP H +F +V R+
Sbjct: 126 LQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-ERFIEIG 184
Query: 754 CAHSKKQGKQEAA 766
SKK K+ AA
Sbjct: 185 SGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 708 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 767
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 768 AALRVLIG 775
AL+ L G
Sbjct: 69 VALKHLKG 76
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 59.7 bits (143), Expect = 2e-08
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 40/193 (20%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
Query: 672 AAEEAMKALHGEA---------------TNSMASDNQVRKIGELV--------------- 701
AAE A+K L G + +S+ D V
Sbjct: 87 AAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPME 146
Query: 702 -------RYLNTNPVGGLLEYARSHGF-AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAV 753
+ NPVG L E G+ E+ + +SGP H +F +V R+
Sbjct: 147 LQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-ERFIEIG 205
Query: 754 CAHSKKQGKQEAA 766
SKK K+ AA
Sbjct: 206 SGTSKKLAKRNAA 218
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 206 SGTSKKLAKRNAAAKMLLRVH 226
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 708 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 767
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
Query: 768 AALRVLIG 775
AL+ L G
Sbjct: 90 VALKHLKG 97
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 59.7 bits (143), Expect = 2e-08
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 40/193 (20%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 672 AAEEAMKALHGEA---------------TNSMASDNQVRKIGELV--------------- 701
AAE A+K L G + +S+ D V
Sbjct: 66 AAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPME 125
Query: 702 -------RYLNTNPVGGLLEYARSHGF-AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAV 753
+ NPVG L E G+ E+ + +SGP H +F +V R+
Sbjct: 126 LQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-ERFIEIG 184
Query: 754 CAHSKKQGKQEAA 766
SKK K+ AA
Sbjct: 185 SGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 708 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 767
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 768 AALRVLIG 775
AL+ L G
Sbjct: 69 VALKHLKG 76
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 57.8 bits (138), Expect = 6e-08
Identities = 55/199 (27%), Positives = 93/199 (46%), Gaps = 15/199 (7%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F +I++SGPPH F +V + G E SKK++K+ A
Sbjct: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRA 232
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A T +L+E K E +K +T + + G +P++ L +
Sbjct: 233 A----TTVLQELKKLPPLPVVEKPKLFFKK------RPKTIVKAGPEYGQGMNPISRLAQ 282
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K ++ LLS+ G +F V VG + + + P+KK+AK+ AAE + L
Sbjct: 283 IQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEV-ATGTGPNKKIAKKNAAEAMLLQL 341
Query: 681 HGEATNSMASDNQVRKIGE 699
+A+ ++ +Q+ K GE
Sbjct: 342 GYKASTNL--QDQLEKTGE 358
Score = 47.0 bits (110), Expect = 1e-04
Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 29/245 (11%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
F Q+ + EF E +++ A+ +AAMKA+ L E + S ++ ES + + +
Sbjct: 114 FYVQLTVGNNEFF-GEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGK---DMDDD 169
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
K A KS ++ + E K F ++ + GP H F V+VG
Sbjct: 170 KDAN--------------KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVG- 214
Query: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQV---RKIGELVRY-----LNT 706
+ SKK++K+ AA ++ L + ++ ++ +V+
Sbjct: 215 EFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGM 274
Query: 707 NPVGGLLEYARS-HGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEA 765
NP+ L + ++ ++ L+ + G P +FV Q KVG +KK K+ A
Sbjct: 275 NPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNE-VATGTGPNKKIAKKNA 333
Query: 766 ADAAL 770
A+A L
Sbjct: 334 AEAML 338
Score = 41.2 bits (95), Expect = 0.006
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Query: 664 SKKVAKQMAAEEAMKALHGEATNSMASDN-QVRKIGELVRYLNTNPVGGLLEYARSHGFA 722
+++ A+ AA +A++AL E + N + K + + N + + + E A
Sbjct: 131 TRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDANKSEISLVFEIALKRNMP 190
Query: 723 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVL 773
F+++ +SGPPH FV + V G + +SKK K+ AA L+ L
Sbjct: 191 VSFEVIKESGPPHMKSFVTRVSV-GEFSAEGEGNSKKLSKKRAATTVLQEL 240
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
Score = 45.8 bits (107), Expect = 2e-04
Identities = 59/250 (23%), Positives = 98/250 (39%), Gaps = 35/250 (14%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
Query: 655 QTFPSVSAPSKKVAKQMAAE---EAMKALHGEATNSMASDNQVRKIGELVRYLNT----- 706
+ SKK++K+ AA E +K L +K +V+ +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 202
Query: 707 --NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQ 763
NP+ L + ++ E+ L+ + G P +FV Q KVG +KK K+
Sbjct: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGT-GTNKKVAKR 261
Query: 764 EAADAALRVL 773
AA+ L +L
Sbjct: 262 NAAENMLEIL 271
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 19/173 (10%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHG 720
+++ AK AA +A++ L E N E LN + + + E A
Sbjct: 60 KGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEE---NLNKSEISQVFEIALKRN 116
Query: 721 FAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVL 773
F++ +SGPPH FV + V G + SKK K+ AA A L L
Sbjct: 117 LPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEEL 168
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
Score = 47.8 bits (112), Expect = 6e-05
Identities = 50/190 (26%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 597 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 649
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
Query: 650 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRY 703
++VG Q F +++ AK AA +A++ L E N E
Sbjct: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEE---N 180
Query: 704 LNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQ 763
LN + + + E A F++ +SGPPH FV + V G + SKK K+
Sbjct: 181 LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKK 239
Query: 764 EAADAALRVL 773
AA A L L
Sbjct: 240 NAAIAVLEEL 249
Score = 45.8 bits (107), Expect = 2e-04
Identities = 59/250 (23%), Positives = 98/250 (39%), Gaps = 35/250 (14%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
Query: 655 QTFPSVSAPSKKVAKQMAAE---EAMKALHGEATNSMASDNQVRKIGELVRYLNT----- 706
+ SKK++K+ AA E +K L +K +V+ +
Sbjct: 224 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 283
Query: 707 --NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQ 763
NP+ L + ++ E+ L+ + G P +FV Q KVG +KK K+
Sbjct: 284 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGT-GTNKKVAKR 342
Query: 764 EAADAALRVL 773
AA+ L +L
Sbjct: 343 NAAENMLEIL 352
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,123,999
Number of Sequences: 37866
Number of extensions: 2414141
Number of successful extensions: 6375
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 6110
Number of HSP's gapped (non-prelim): 204
length of query: 1181
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1068
effective length of database: 13,968,660
effective search space: 14918528880
effective search space used: 14918528880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.