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Search of human proteins with 70166944
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
(1200 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 2431 0.0
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 2417 0.0
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 2382 0.0
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 1817 0.0
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 266 7e-71
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 257 4e-68
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 253 1e-66
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 251 4e-66
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 237 6e-62
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 138 4e-32
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 138 4e-32
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 128 4e-29
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 119 2e-26
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 108 2e-23
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 82 3e-15
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 68 6e-11
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 68 6e-11
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 68 6e-11
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 66 2e-10
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 63 1e-09
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 63 1e-09
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 63 1e-09
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 62 3e-09
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 62 3e-09
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 62 3e-09
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 62 4e-09
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 62 4e-09
gi|82659089 staufen isoform a [Homo sapiens] 56 2e-07
gi|82659087 staufen isoform b [Homo sapiens] 56 2e-07
gi|82659085 staufen isoform a [Homo sapiens] 56 2e-07
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 2431 bits (6300), Expect = 0.0
Identities = 1200/1200 (100%), Positives = 1200/1200 (100%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 781 KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 840
KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR
Sbjct: 781 KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 840
Query: 841 KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE 900
KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE
Sbjct: 841 KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE 900
Query: 901 LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES 960
LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES
Sbjct: 901 LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES 960
Query: 961 RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL 1020
RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL
Sbjct: 961 RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL 1020
Query: 1021 GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV 1080
GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV
Sbjct: 1021 GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV 1080
Query: 1081 GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK 1140
GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK
Sbjct: 1081 GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK 1140
Query: 1141 KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1200
KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1141 KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1200
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 2417 bits (6263), Expect = 0.0
Identities = 1200/1226 (97%), Positives = 1200/1226 (97%), Gaps = 26/1226 (2%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 781 KQEAADAALRVLIGENEKAERMGFTE--------------------------LPLTGSTF 814
KQEAADAALRVLIGENEKAERMGFTE LPLTGSTF
Sbjct: 781 KQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF 840
Query: 815 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 874
HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS
Sbjct: 841 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 900
Query: 875 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 934
LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY
Sbjct: 901 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 960
Query: 935 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 994
ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP
Sbjct: 961 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 1020
Query: 995 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1054
TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI
Sbjct: 1021 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1080
Query: 1055 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1114
CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD
Sbjct: 1081 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1140
Query: 1115 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1174
GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK
Sbjct: 1141 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200
Query: 1175 KGLKDMGYGNWISKPQEEKNFYLCPV 1200
KGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1201 KGLKDMGYGNWISKPQEEKNFYLCPV 1226
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 2382 bits (6173), Expect = 0.0
Identities = 1181/1200 (98%), Positives = 1181/1200 (98%), Gaps = 19/1200 (1%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ VRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ-------------------VRKIGELV 701
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 702 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 761
Query: 781 KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 840
KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR
Sbjct: 762 KQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 821
Query: 841 KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE 900
KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE
Sbjct: 822 KILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSE 881
Query: 901 LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES 960
LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES
Sbjct: 882 LMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTES 941
Query: 961 RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL 1020
RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL
Sbjct: 942 RHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVL 1001
Query: 1021 GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV 1080
GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV
Sbjct: 1002 GLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKV 1061
Query: 1081 GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK 1140
GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK
Sbjct: 1062 GRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLFK 1121
Query: 1141 KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1200
KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1122 KLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1181
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 1817 bits (4706), Expect = 0.0
Identities = 905/931 (97%), Positives = 905/931 (97%), Gaps = 26/931 (2%)
Query: 296 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 355
MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL
Sbjct: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
Query: 356 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 415
TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP
Sbjct: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
Query: 416 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 475
VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA
Sbjct: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
Query: 476 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 535
IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF
Sbjct: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
Query: 536 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 595
KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK
Sbjct: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
Query: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ
Sbjct: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
Query: 656 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 715
TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK
Sbjct: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
Query: 716 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 775
IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH
Sbjct: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
Query: 776 SKKQGKQEAADAALRVLIGENEKAERMGFTE--------------------------LPL 809
SKKQGKQEAADAALRVLIGENEKAERMGFTE LPL
Sbjct: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
Query: 810 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 869
TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK
Sbjct: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
Query: 870 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 929
GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV
Sbjct: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
Query: 930 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 989
SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES
Sbjct: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
Query: 990 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 1049
SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH
Sbjct: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
Query: 1050 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 1109
LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD
Sbjct: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
Query: 1110 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 1169
LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA
Sbjct: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
Query: 1170 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1200
KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
Score = 33.1 bits (74), Expect = 1.6
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 156 TTAHDLSGKLGTPK-KEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPD 214
++A +L+ +G K ++IN VL + ++G + ++ TPP+W + T + + R
Sbjct: 18 SSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL---TDKKRERMQIKR-- 72
Query: 215 GHSQGAPNSDPSLEPEDRNS 234
++ P + P+ PE + +
Sbjct: 73 -NTNSVPETAPAAIPETKRN 91
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 266 bits (681), Expect = 7e-71
Identities = 175/482 (36%), Positives = 259/482 (53%), Gaps = 53/482 (10%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 803 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 856
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 857 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 913
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 914 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPK--- 970
F+ ++ G ++K+ V FHLYIST+PCGD +F S H P+ E P
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIF-------------SPHEPILEEPADRH 471
Query: 971 -----QGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGA 1025
+G+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+
Sbjct: 472 PNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGS 531
Query: 1026 LLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSI 1085
LL+ F++PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S
Sbjct: 532 LLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISN 586
Query: 1086 YDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF------ 1139
++ RQ GK SVNW + D +E+++ T G ++EL R S+ L+
Sbjct: 587 AEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRV 639
Query: 1140 -KKLCSFRYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYL 1197
K+ S R + + + Y E+K AA++Y+ AK G G W+ KP E+ F L
Sbjct: 640 HGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSL 699
Query: 1198 CP 1199
P
Sbjct: 700 TP 701
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 257 bits (657), Expect = 4e-68
Identities = 167/446 (37%), Positives = 234/446 (52%), Gaps = 20/446 (4%)
Query: 758 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQ 817
FV V GR F SKK + +AA AAL+ L G F D
Sbjct: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADS 364
Query: 818 IAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSED-MGVVVSLGTGNRCVKGDSLSLK 876
I+ L + F +T P K LA I+M K + VV+L +G +C+ G+ LS +
Sbjct: 365 ISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEHLSDQ 424
Query: 877 GETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDS---IFEPAKGGEKLQIKKTVSFHL 933
G VNDCHAE+++RR F+ FLY++L + S+ +DS IF K G ++++ + FHL
Sbjct: 425 GLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGG-YRLRENILFHL 483
Query: 934 YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 993
Y+ST+PCGD L S + + S+H +G LRTK+E+GEGT+PV V
Sbjct: 484 YVSTSPCGDARLH--SPYEITTDLHSSKH---LVRKFRGHLRTKIESGEGTVPVRGPSAV 538
Query: 994 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRA 1053
TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL+HF++P+YL+S+ +G L GHL R
Sbjct: 539 QTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARV 598
Query: 1054 ICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEIL 1113
+ R+ G RH N P + VS ++ RQ GK+ S+NW + DLEI+
Sbjct: 599 MSHRMEGVGQ-LPASYRH----NRPLLSGVSDAEA-RQPGKSPPFSMNWVVGSA-DLEII 651
Query: 1114 DGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKN 1171
+ T G + GP V L+ +L + Y EAK A Y++ K
Sbjct: 652 NATTGRRSCGGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQ 711
Query: 1172 YFKKGLKDMGYGNWISKPQEEKNFYL 1197
K + G G W+ KP E++ F L
Sbjct: 712 QLFKAFQKAGLGTWVRKPPEQQQFLL 737
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 614 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 673
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
Query: 674 EEAMKA 679
E A+++
Sbjct: 183 ELALRS 188
Score = 35.8 bits (81), Expect = 0.25
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
Score = 33.9 bits (76), Expect = 0.95
Identities = 51/246 (20%), Positives = 88/246 (35%), Gaps = 59/246 (23%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
Query: 567 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 595
L +E A + + S+ Y + +
Sbjct: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
Query: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
Query: 656 TFPSVSAPSKKVAKQMAAEEAMKALH-----GEATNSMASDNQPEGMISESLDNLESMMP 710
TF S SKK+A+ AA+ A++ L G A P+ E D++ ++
Sbjct: 316 TFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQ----EFADSISQLVT 370
Query: 711 NKVRKI 716
K R++
Sbjct: 371 QKFREV 376
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 253 bits (645), Expect = 1e-66
Identities = 174/509 (34%), Positives = 264/509 (51%), Gaps = 67/509 (13%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 803 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 856
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 857 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 913
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 914 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD---------KSCSDRAME-----STE 959
F+ ++ G ++K+ V FHLYIST+PCGD +F +S + ++ S +
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQ 484
Query: 960 SRHYPVFENPK---------------------QGKLRTKVENGEGTIPVESSDIVPTWDG 998
R + +P +G+LRTK+E+GEGTIPV S+ + TWDG
Sbjct: 485 PRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDG 544
Query: 999 IRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRV 1058
+ GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 545 VLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI 604
Query: 1059 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1118
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 605 ----SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG 657
Query: 1119 TVDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1170
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 658 -----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
Query: 1171 NYFKKGLKDMGYGNWISKPQEEKNFYLCP 1199
G G W+ KP E+ F L P
Sbjct: 713 ARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 251 bits (640), Expect = 4e-66
Identities = 166/453 (36%), Positives = 248/453 (54%), Gaps = 53/453 (11%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 803 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 856
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 857 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 913
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 914 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPK--- 970
F+ ++ G ++K+ V FHLYIST+PCGD +F S H P+ E P
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIF-------------SPHEPILEEPADRH 471
Query: 971 -----QGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGA 1025
+G+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+
Sbjct: 472 PNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGS 531
Query: 1026 LLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSI 1085
LL+ F++PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S
Sbjct: 532 LLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISN 586
Query: 1086 YDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF------ 1139
++ RQ GK SVNW + D +E+++ T G ++EL R S+ L+
Sbjct: 587 AEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRV 639
Query: 1140 -KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1170
K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 640 HGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 672
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 237 bits (604), Expect = 6e-62
Identities = 165/480 (34%), Positives = 253/480 (52%), Gaps = 67/480 (13%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
Query: 803 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 856
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
Query: 857 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 913
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
Query: 914 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD---------KSCSDRAME-----STE 959
F+ ++ G ++K+ V FHLYIST+PCGD +F +S + ++ S +
Sbjct: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQ 484
Query: 960 SRHYPVFENPK---------------------QGKLRTKVENGEGTIPVESSDIVPTWDG 998
R + +P +G+LRTK+E+GEGTIPV S+ + TWDG
Sbjct: 485 PRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDG 544
Query: 999 IRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRV 1058
+ GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 545 VLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI 604
Query: 1059 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1118
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 605 ----SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG 657
Query: 1119 TVDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1170
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 658 -----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 138 bits (347), Expect = 4e-32
Identities = 140/539 (25%), Positives = 238/539 (44%), Gaps = 62/539 (11%)
Query: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 36 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 94
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEK---- 798
+ K +G P F + A V G + +KK+ + AA AL L+ +E
Sbjct: 95 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 154
Query: 799 ----------AERMGFTELPLTGSTFHD-------QIAMLSHRCFNTLTNSFQPSLLGRK 841
AE + +EL ++ +I+ + FN L ++ L
Sbjct: 155 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSS 214
Query: 842 ILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSEL 901
LAA I+++ + VV++GTG D + G ++D HA + +RR +R+ Y +L
Sbjct: 215 SLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLRYFYRQL 271
Query: 902 MKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 958
+ + S+ + SIF L +K+ ++ LY++ P G + ++
Sbjct: 272 LLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQLRL 324
Query: 959 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 1018
FE ++ L VE G I + + DG+ R+ +MS SDK+ RW
Sbjct: 325 NPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLTRWE 375
Query: 1019 VLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHPFIV 1075
VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L ++V
Sbjct: 376 VLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMFYLV 431
Query: 1076 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNELSR 1129
N P + V + + + K S+NW D LEI+DG G + + SR
Sbjct: 432 NRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSMASR 490
Query: 1130 VSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISK 1188
+ K + F L + L +Y AK + Y+ AK K L+ GYG+WI K
Sbjct: 491 LCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVK 549
Score = 33.9 bits (76), Expect = 0.95
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 138 KLALDELLQ 146
>gi|21245124 adenosine deaminase domain containing 1 (testis-specific)
isoform 1 [Homo sapiens]
Length = 576
Score = 138 bits (347), Expect = 4e-32
Identities = 140/539 (25%), Positives = 238/539 (44%), Gaps = 62/539 (11%)
Query: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEK---- 798
+ K +G P F + A V G + +KK+ + AA AL L+ +E
Sbjct: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
Query: 799 ----------AERMGFTELPLTGSTFHD-------QIAMLSHRCFNTLTNSFQPSLLGRK 841
AE + +EL ++ +I+ + FN L ++ L
Sbjct: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSS 232
Query: 842 ILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSEL 901
LAA I+++ + VV++GTG D + G ++D HA + +RR +R+ Y +L
Sbjct: 233 SLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLRYFYRQL 289
Query: 902 MKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 958
+ + S+ + SIF L +K+ ++ LY++ P G + ++
Sbjct: 290 LLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQLRL 342
Query: 959 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 1018
FE ++ L VE G I + + DG+ R+ +MS SDK+ RW
Sbjct: 343 NPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLTRWE 393
Query: 1019 VLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHPFIV 1075
VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L ++V
Sbjct: 394 VLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMFYLV 449
Query: 1076 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNELSR 1129
N P + V + + + K S+NW D LEI+DG G + + SR
Sbjct: 450 NRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSMASR 508
Query: 1130 VSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISK 1188
+ K + F L + L +Y AK + Y+ AK K L+ GYG+WI K
Sbjct: 509 LCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVK 567
Score = 33.9 bits (76), Expect = 0.95
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 128 bits (321), Expect = 4e-29
Identities = 138/536 (25%), Positives = 231/536 (43%), Gaps = 67/536 (12%)
Query: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEK---- 798
+ K +G P F + A V G + +KK+ + AA AL L+ +E
Sbjct: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
Query: 799 ----------AERMGFTELPLTGSTFHD-------QIAMLSHRCFNTLTNSFQPSLLGRK 841
AE + +EL ++ +I+ + FN L ++ L
Sbjct: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSS 232
Query: 842 ILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSEL 901
LAA I+++ + VV++GTG D + G ++D HA + +RR L
Sbjct: 233 SLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRS--------L 281
Query: 902 MKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESR 961
+ N + SIF L +K+ ++ LY++ P G + ++
Sbjct: 282 LSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQLRLNPH 334
Query: 962 HYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLG 1021
FE ++ L VE G I + + DG+ R+ +MS SDK+ RW VLG
Sbjct: 335 SISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLTRWEVLG 385
Query: 1022 LQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHPFIVNHP 1078
+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L ++VN P
Sbjct: 386 VQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRP 441
Query: 1079 KVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNELSRVSK 1132
+ V + + + K S+NW D LEI+DG G + + SR+ K
Sbjct: 442 HISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSMASRLCK 500
Query: 1133 KNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISK 1188
+ F L + L +Y AK + Y+ AK K L+ GYG+WI K
Sbjct: 501 AAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVK 556
Score = 33.9 bits (76), Expect = 0.95
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|223972690 adenosine deaminase domain containing 2 isoform 2 [Homo
sapiens]
Length = 583
Score = 119 bits (298), Expect = 2e-26
Identities = 136/482 (28%), Positives = 206/482 (42%), Gaps = 48/482 (9%)
Query: 731 LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 790
L EYA S G F+ DQ P P F A++ G PA A+SK + KQ+AA +AL
Sbjct: 120 LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
Query: 791 VLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKIL 843
+ + E E + P + I RC F+ L + P + +
Sbjct: 178 YIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTV 237
Query: 844 AAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRF 896
A +I++++ +++ +V+LGTG+ C G L G+ ++DCH +I+RR +RF
Sbjct: 238 AGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRF 296
Query: 897 LYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 952
L+ +L+ + + + S+ P G G +K V HLYIS P G + D
Sbjct: 297 LFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARD 349
Query: 953 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 1012
+ T P +P +L+ V + + + T G +S SD
Sbjct: 350 IYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASD 398
Query: 1013 KILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRH 1071
K+ RW VLGL GALL H + P+Y S+ L L+RAI R D S L
Sbjct: 399 KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPP 457
Query: 1072 PFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNEL 1127
P++ H G + S+ + S+NW L D +E++D G V +
Sbjct: 458 PYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPP 515
Query: 1128 SRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWIS 1187
SR+ K + F + + LL L EA KA Y+ A+ L G G W S
Sbjct: 516 SRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPS 574
Query: 1188 KP 1189
KP
Sbjct: 575 KP 576
>gi|223972688 adenosine deaminase domain containing 2 isoform 1 [Homo
sapiens]
Length = 665
Score = 108 bits (271), Expect = 2e-23
Identities = 128/476 (26%), Positives = 198/476 (41%), Gaps = 58/476 (12%)
Query: 747 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 806
V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E +
Sbjct: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
Query: 807 LPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKILAAIIMKKD-------- 851
P + I RC F+ L + P + +A +I+++
Sbjct: 266 RPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSC 325
Query: 852 ---------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELM 902
+++ +V+LGTG+ C G L G+ ++DCH +I+RR +RFL+ +L+
Sbjct: 326 TEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLL 384
Query: 903 ---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 958
+ + + S+ P G G +K V HLYIS P G + D + T
Sbjct: 385 LATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARDIYLPPT 437
Query: 959 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 1018
P +P +L+ V + + + T G +S SDK+ RW
Sbjct: 438 SEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASDKLARWA 486
Query: 1019 VLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRHPFI--V 1075
VLGL GALL H + P+Y S+ L L+RAI R D S L P++
Sbjct: 487 VLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPPPYVRTA 545
Query: 1076 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNELSRVSKK 1133
H G + S+ + S+NW L D +E++D G V + SR+ K
Sbjct: 546 LHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPPSRLCKA 603
Query: 1134 NIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKP 1189
+ F + + LL L EA KA Y+ A+ L G G W SKP
Sbjct: 604 SFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPSKP 658
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 82.0 bits (201), Expect = 3e-15
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 37/221 (16%)
Query: 1002 GERLRTMSCSDKILRWNVLGLQGALLTHFL-QPIYLKSVTLGYL-FSQGHLTRAICCRVT 1059
G+R R+MSCSDK+ RWNVLG QGALL H L +PIYL +V +G +SQ + RA+ R
Sbjct: 291 GDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGR-C 349
Query: 1060 RDGSAFEDGLRHPFIVNHPKVGRVS-IYDSKRQSGKTKE-----------TSVNWCLADG 1107
++ SA G F V K+ + +++ R + + K +++W
Sbjct: 350 QNVSALPKG----FGVQELKILQSDLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPE 405
Query: 1108 YDLEIL-----DGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRD----LLRL---- 1154
L++ GT G S++SK +F F+KL S R RD LR+
Sbjct: 406 QPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLS-RIARDKWPHSLRVQKLD 464
Query: 1155 SYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNF 1195
+Y E K+AA Y+ A + +K + +G+WI P + F
Sbjct: 465 TYQEYKEAASSYQEAWSTLRKQV----FGSWIRNPPDYHQF 501
Score = 64.7 bits (156), Expect = 5e-10
Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 858 VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPA 917
+VS+GTG +C+ + G+ +ND HAE+I+RR F R+L +L + + +DSIF P
Sbjct: 61 IVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQL-QLAATLKEDSIFVPG 119
Query: 918 KGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFEN 968
++++ + F + S PCGD ++ +E + PVF N
Sbjct: 120 TQKGVWKLRRDLIFVFFSSHTPCGDASIIP------MLEFEDQPCCPVFRN 164
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 66 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 119
Query: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 120 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 178
Query: 767 RWFPAVCAHSKKQGKQEAA 785
R+ SKK K+ AA
Sbjct: 179 RFIEIGSGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 35.0 bits (79), Expect = 0.43
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 787 AALRVLIG 794
AL+ L G
Sbjct: 69 VALKHLKG 76
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
Query: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 87 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 140
Query: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 141 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 199
Query: 767 RWFPAVCAHSKKQGKQEAA 785
R+ SKK K+ AA
Sbjct: 200 RFIEIGSGTSKKLAKRNAA 218
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 206 SGTSKKLAKRNAAAKMLLRVH 226
Score = 35.0 bits (79), Expect = 0.43
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
Query: 787 AALRVLIG 794
AL+ L G
Sbjct: 90 VALKHLKG 97
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 66 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 119
Query: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 120 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 178
Query: 767 RWFPAVCAHSKKQGKQEAA 785
R+ SKK K+ AA
Sbjct: 179 RFIEIGSGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 35.0 bits (79), Expect = 0.43
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 787 AALRVLIG 794
AL+ L G
Sbjct: 69 VALKHLKG 76
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 65.9 bits (159), Expect = 2e-10
Identities = 58/201 (28%), Positives = 96/201 (47%), Gaps = 30/201 (14%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
Query: 567 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 620
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
Query: 621 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
Query: 681 HGEATNSMASDNQPEGMISES 701
+ A++N+ + +I ++
Sbjct: 575 F---SGPNAANNKKKKIIPQA 592
Score = 61.6 bits (148), Expect = 4e-09
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 24/187 (12%)
Query: 623 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHG 682
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+ G
Sbjct: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAM-G 452
Query: 683 EATNSMA----------SDNQP--EGMISESLDN-----LESMMPNKVRKIGELVRYLNT 725
T A SDN+ E + S S +N E+ +VR G ++
Sbjct: 453 YPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK 512
Query: 726 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 785
NPV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 513 NPVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAA 567
Query: 786 DAALRVL 792
AAL L
Sbjct: 568 LAALEKL 574
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 L 680
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 745
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 746 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 L 680
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 745
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 746 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 L 680
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 745
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 746 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 62.4 bits (150), Expect = 3e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 734 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEIL- 75
Query: 794 GENEKAERMGFTELPLTGSTFHDQIAM 820
E+ + L LT + + ++M
Sbjct: 76 ----NKEKKAVSPLLLTTTNSSEGLSM 98
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 683
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 684 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 740
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 741 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 795
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 3e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 734 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEIL- 75
Query: 794 GENEKAERMGFTELPLTGSTFHDQIAM 820
E+ + L LT + + ++M
Sbjct: 76 ----NKEKKAVSPLLLTTTNSSEGLSM 98
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 683
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 684 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 740
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 741 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 795
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 3e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 48.1 bits (113), Expect = 5e-05
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 734 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEIL- 75
Query: 794 GENEKAERMGFTELPLTGSTFHDQIAM 820
E+ + L LT + + ++M
Sbjct: 76 ----NKEKKAVSPLLLTTTNSSEGLSM 98
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 683
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 684 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 740
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 741 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 795
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 61.6 bits (148), Expect = 4e-09
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 21/179 (11%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 621
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 622 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKL 592
Score = 57.4 bits (137), Expect = 8e-08
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 37/238 (15%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMPN-----KVRKIGELVRYLNTNPVGGLLEYARSHGFA 741
+ E++ + P+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 742 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 61.6 bits (148), Expect = 4e-09
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 21/179 (11%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 621
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 622 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKL 592
Score = 57.4 bits (137), Expect = 8e-08
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 37/238 (15%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMPN-----KVRKIGELVRYLNTNPVGGLLEYARSHGFA 741
+ E++ + P+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 742 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
Score = 44.7 bits (104), Expect = 5e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
Query: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
Query: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
+KK K+ AA+ L +L
Sbjct: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
Score = 39.7 bits (91), Expect = 0.017
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
Query: 781 KQEAADAALRVL 792
K+ AA A L L
Sbjct: 157 KKNAAIAVLEEL 168
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
Score = 44.7 bits (104), Expect = 5e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
Query: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 224 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 267
Query: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 268 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
Query: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
+KK K+ AA+ L +L
Sbjct: 328 HTAEGT-GTNKKVAKRNAAENMLEIL 352
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 40/209 (19%)
Query: 597 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 649
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
Query: 650 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLD 703
++VG Q F +++ AK AA +A++ L E PE + ++
Sbjct: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVN 172
Query: 704 NLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 763
ES N LN + + + E A F++ +SGPPH FV +
Sbjct: 173 GRESEEEN-----------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
Query: 764 VGGRWFPAVCAHSKKQGKQEAADAALRVL 792
V G + SKK K+ AA A L L
Sbjct: 222 V-GEFVGEGEGKSKKISKKNAAIAVLEEL 249
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
Score = 44.7 bits (104), Expect = 5e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
Query: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
Query: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
+KK K+ AA+ L +L
Sbjct: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
Score = 39.7 bits (91), Expect = 0.017
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
Query: 781 KQEAADAALRVL 792
K+ AA A L L
Sbjct: 157 KKNAAIAVLEEL 168
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,761,150
Number of Sequences: 37866
Number of extensions: 2443791
Number of successful extensions: 6511
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 6249
Number of HSP's gapped (non-prelim): 200
length of query: 1200
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1086
effective length of database: 13,930,794
effective search space: 15128842284
effective search space used: 15128842284
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.