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Search of human proteins with 70166852
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
(1226 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 2479 0.0
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 2417 0.0
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 2368 0.0
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 1880 0.0
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 266 7e-71
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 253 1e-66
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 251 4e-66
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 250 7e-66
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 237 6e-62
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 136 1e-31
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 136 1e-31
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 126 1e-28
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 115 3e-25
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 105 3e-22
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 82 3e-15
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 68 6e-11
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 68 6e-11
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 68 6e-11
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 66 2e-10
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 63 2e-09
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 63 2e-09
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 63 2e-09
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 62 3e-09
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 62 3e-09
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 62 3e-09
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 62 4e-09
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 62 4e-09
gi|82659089 staufen isoform a [Homo sapiens] 56 2e-07
gi|82659087 staufen isoform b [Homo sapiens] 56 2e-07
gi|82659085 staufen isoform a [Homo sapiens] 56 2e-07
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 2479 bits (6426), Expect = 0.0
Identities = 1226/1226 (100%), Positives = 1226/1226 (100%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 781 KQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF 840
KQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF
Sbjct: 781 KQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF 840
Query: 841 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 900
HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS
Sbjct: 841 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 900
Query: 901 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 960
LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY
Sbjct: 901 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 960
Query: 961 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 1020
ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP
Sbjct: 961 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 1020
Query: 1021 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1080
TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI
Sbjct: 1021 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1080
Query: 1081 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1140
CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD
Sbjct: 1081 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1140
Query: 1141 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200
GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK
Sbjct: 1141 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200
Query: 1201 KGLKDMGYGNWISKPQEEKNFYLCPV 1226
KGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1201 KGLKDMGYGNWISKPQEEKNFYLCPV 1226
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 2417 bits (6263), Expect = 0.0
Identities = 1200/1226 (97%), Positives = 1200/1226 (97%), Gaps = 26/1226 (2%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
Query: 781 KQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF 840
KQEAADAALRVLIGENEKAERMGFTE LPLTGSTF
Sbjct: 781 KQEAADAALRVLIGENEKAERMGFTE--------------------------LPLTGSTF 814
Query: 841 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 900
HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS
Sbjct: 815 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 874
Query: 901 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 960
LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY
Sbjct: 875 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 934
Query: 961 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 1020
ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP
Sbjct: 935 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 994
Query: 1021 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1080
TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI
Sbjct: 995 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1054
Query: 1081 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1140
CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD
Sbjct: 1055 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1114
Query: 1141 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200
GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK
Sbjct: 1115 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1174
Query: 1201 KGLKDMGYGNWISKPQEEKNFYLCPV 1226
KGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1175 KGLKDMGYGNWISKPQEEKNFYLCPV 1200
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 2368 bits (6136), Expect = 0.0
Identities = 1181/1226 (96%), Positives = 1181/1226 (96%), Gaps = 45/1226 (3%)
Query: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ
Sbjct: 1 MNPRQGYSLSGYYTHPFQGYEHRQLRYQQPGPGSSPSSFLLKQIEFLKGQLPEAPVIGKQ 60
Query: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ
Sbjct: 61 TPSLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPRGVHLGSQGLQRGFQHPSPRGRSLPQ 120
Query: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA
Sbjct: 121 RGVDCLSSHFQELSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLA 180
Query: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED
Sbjct: 181 KKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSED 240
Query: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK
Sbjct: 241 LLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK 300
Query: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR
Sbjct: 301 EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHLTDKKR 360
Query: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE
Sbjct: 361 ERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEPVIKLE 420
Query: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP
Sbjct: 421 NRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMP 480
Query: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV
Sbjct: 481 SFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVV 540
Query: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ
Sbjct: 541 INGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQ 600
Query: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV
Sbjct: 601 TPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV 660
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ VRKIGELV
Sbjct: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQ-------------------VRKIGELV 701
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG
Sbjct: 702 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 761
Query: 781 KQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF 840
KQEAADAALRVLIGENEKAERMGFTE LPLTGSTF
Sbjct: 762 KQEAADAALRVLIGENEKAERMGFTE--------------------------LPLTGSTF 795
Query: 841 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 900
HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS
Sbjct: 796 HDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS 855
Query: 901 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 960
LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY
Sbjct: 856 LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLY 915
Query: 961 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 1020
ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP
Sbjct: 916 ISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVP 975
Query: 1021 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1080
TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI
Sbjct: 976 TWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAI 1035
Query: 1081 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1140
CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD
Sbjct: 1036 CCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILD 1095
Query: 1141 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200
GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK
Sbjct: 1096 GTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1155
Query: 1201 KGLKDMGYGNWISKPQEEKNFYLCPV 1226
KGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 1156 KGLKDMGYGNWISKPQEEKNFYLCPV 1181
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 1880 bits (4869), Expect = 0.0
Identities = 931/931 (100%), Positives = 931/931 (100%)
Query: 296 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 355
MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL
Sbjct: 1 MAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL 60
Query: 356 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 415
TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP
Sbjct: 61 TDKKRERMQIKRNTNSVPETAPAAIPETKRNAEFLTCNIPTSNASNNMVTTEKVENGQEP 120
Query: 416 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 475
VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA
Sbjct: 121 VIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRA 180
Query: 476 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 535
IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF
Sbjct: 181 IMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRF 240
Query: 536 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 595
KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK
Sbjct: 241 KFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESEK 300
Query: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ
Sbjct: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
Query: 656 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 715
TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK
Sbjct: 361 TFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRK 420
Query: 716 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 775
IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH
Sbjct: 421 IGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAH 480
Query: 776 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 835
SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL
Sbjct: 481 SKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPL 540
Query: 836 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 895
TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK
Sbjct: 541 TGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVK 600
Query: 896 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 955
GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV
Sbjct: 601 GDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTV 660
Query: 956 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 1015
SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES
Sbjct: 661 SFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVES 720
Query: 1016 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 1075
SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH
Sbjct: 721 SDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGH 780
Query: 1076 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 1135
LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD
Sbjct: 781 LTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYD 840
Query: 1136 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 1195
LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA
Sbjct: 841 LEILDGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETA 900
Query: 1196 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 1226
KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV
Sbjct: 901 KNYFKKGLKDMGYGNWISKPQEEKNFYLCPV 931
Score = 33.1 bits (74), Expect = 1.7
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 156 TTAHDLSGKLGTPK-KEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPD 214
++A +L+ +G K ++IN VL + ++G + ++ TPP+W + T + + R
Sbjct: 18 SSALNLAKNIGLTKARDINAVLIDMERQGDVYRQGTTPPIWHL---TDKKRERMQIKR-- 72
Query: 215 GHSQGAPNSDPSLEPEDRNS 234
++ P + P+ PE + +
Sbjct: 73 -NTNSVPETAPAAIPETKRN 91
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 266 bits (681), Expect = 7e-71
Identities = 180/508 (35%), Positives = 264/508 (51%), Gaps = 79/508 (15%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 856
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 857 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 915
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 916 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 973
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIF- 457
Query: 974 KSCSDRAMESTESRHYPVFENPK--------QGKLRTKVENGEGTIPVESSDIVPTWDGI 1025
S H P+ E P +G+LRTK+E+GEGTIPV S+ + TWDG+
Sbjct: 458 ------------SPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGV 505
Query: 1026 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVT 1085
GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 506 LQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI- 564
Query: 1086 RDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGT 1145
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 565 ---SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG- 617
Query: 1146 VDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAKN 1197
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 618 ----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKA 673
Query: 1198 YFKKGLKDMGYGNWISKPQEEKNFYLCP 1225
G G W+ KP E+ F L P
Sbjct: 674 RLFTAFIKAGLGAWVEKPTEQDQFSLTP 701
Score = 47.4 bits (111), Expect = 9e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.12
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 253 bits (645), Expect = 1e-66
Identities = 179/535 (33%), Positives = 269/535 (50%), Gaps = 93/535 (17%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 856
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 857 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 915
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 916 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 973
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIFS 458
Query: 974 ---------KSCSDRAME-----STESRHYPVFENPK---------------------QG 998
+S + ++ S + R + +P +G
Sbjct: 459 PHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARG 518
Query: 999 KLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQ 1058
+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+LL+ F++
Sbjct: 519 QLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVE 578
Query: 1059 PIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQS 1118
PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S ++ RQ
Sbjct: 579 PIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISNAEA-RQP 632
Query: 1119 GKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF-------KKLCSF 1171
GK SVNW + D +E+++ T G ++EL R S+ L+ K+ S
Sbjct: 633 GKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRVHGKVPSH 686
Query: 1172 RYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCP 1225
R + + + Y E+K AA++Y+ AK G G W+ KP E+ F L P
Sbjct: 687 LLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
Score = 47.4 bits (111), Expect = 9e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.12
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 251 bits (640), Expect = 4e-66
Identities = 171/479 (35%), Positives = 253/479 (52%), Gaps = 79/479 (16%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 856
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 857 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 915
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 916 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 973
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIF- 457
Query: 974 KSCSDRAMESTESRHYPVFENPK--------QGKLRTKVENGEGTIPVESSDIVPTWDGI 1025
S H P+ E P +G+LRTK+E+GEGTIPV S+ + TWDG+
Sbjct: 458 ------------SPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGV 505
Query: 1026 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRVT 1085
GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 506 LQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI- 564
Query: 1086 RDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGT 1145
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 565 ---SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG- 617
Query: 1146 VDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1196
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 618 ----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 672
Score = 47.4 bits (111), Expect = 9e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.12
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 250 bits (638), Expect = 7e-66
Identities = 169/472 (35%), Positives = 237/472 (50%), Gaps = 46/472 (9%)
Query: 758 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRR 817
FV V GR F SKK + +AA AAL+ L G TP+
Sbjct: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMP------ 358
Query: 818 TMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKD 877
F D I+ L + F +T P K LA I+M K
Sbjct: 359 --------------------QEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKG 398
Query: 878 SED-MGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAK 936
+ VV+L +G +C+ G+ LS +G VNDCHAE+++RR F+ FLY++L + S+ +
Sbjct: 399 LDARQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRRE 458
Query: 937 DS---IFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFE 993
DS IF K G ++++ + FHLY+ST+PCGD L S + + S+H
Sbjct: 459 DSERSIFVRLKEGG-YRLRENILFHLYVSTSPCGDARLH--SPYEITTDLHSSKH---LV 512
Query: 994 NPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALL 1053
+G LRTK+E+GEGT+PV V TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL
Sbjct: 513 RKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALL 572
Query: 1054 THFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYD 1113
+HF++P+YL+S+ +G L GHL R + R+ G RH N P + VS +
Sbjct: 573 SHFVEPVYLQSIVVGSLHHTGHLARVMSHRMEGVGQ-LPASYRH----NRPLLSGVSDAE 627
Query: 1114 SKRQSGKTKETSVNWCLADGYDLEILDGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSF 1171
+ RQ GK+ S+NW + DLEI++ T G + GP V L+ +L +
Sbjct: 628 A-RQPGKSPPFSMNWVVGSA-DLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRLSTR 685
Query: 1172 RYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYL 1223
Y EAK A Y++ K K + G G W+ KP E++ F L
Sbjct: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQFLL 737
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 614 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 673
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
Query: 674 EEAMKA 679
E A+++
Sbjct: 183 ELALRS 188
Score = 35.8 bits (81), Expect = 0.26
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
Score = 33.9 bits (76), Expect = 0.98
Identities = 51/246 (20%), Positives = 88/246 (35%), Gaps = 59/246 (23%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
Query: 567 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 595
L +E A + + S+ Y + +
Sbjct: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
Query: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
Query: 656 TFPSVSAPSKKVAKQMAAEEAMKALH-----GEATNSMASDNQPEGMISESLDNLESMMP 710
TF S SKK+A+ AA+ A++ L G A P+ E D++ ++
Sbjct: 316 TFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQ----EFADSISQLVT 370
Query: 711 NKVRKI 716
K R++
Sbjct: 371 QKFREV 376
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 237 bits (604), Expect = 6e-62
Identities = 170/506 (33%), Positives = 258/506 (50%), Gaps = 93/506 (18%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
Query: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 856
L L ++P QP +P G H D ++ L F LT
Sbjct: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
Query: 857 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 915
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
Query: 916 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 973
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIFS 458
Query: 974 ---------KSCSDRAME-----STESRHYPVFENPK---------------------QG 998
+S + ++ S + R + +P +G
Sbjct: 459 PHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARG 518
Query: 999 KLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQ 1058
+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+LL+ F++
Sbjct: 519 QLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVE 578
Query: 1059 PIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQS 1118
PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S ++ RQ
Sbjct: 579 PIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISNAEA-RQP 632
Query: 1119 GKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF-------KKLCSF 1171
GK SVNW + D +E+++ T G ++EL R S+ L+ K+ S
Sbjct: 633 GKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRVHGKVPSH 686
Query: 1172 RYRRDLLRLS-YGEAKKAARDYETAK 1196
R + + + Y E+K AA++Y+ AK
Sbjct: 687 LLRSKITKPNVYHESKLAAKEYQAAK 712
Score = 47.4 bits (111), Expect = 9e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
Query: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
K+E S S
Sbjct: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
Query: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
Query: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
V Q F S +KK+AK AA+ A+ A+
Sbjct: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
Score = 42.4 bits (98), Expect = 0.003
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
Query: 675 EAMKA 679
+A+++
Sbjct: 137 KALRS 141
Score = 37.0 bits (84), Expect = 0.12
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 136 bits (343), Expect = 1e-31
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 36 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 94
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 95 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 154
Query: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 861
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 155 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 208
Query: 862 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 921
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 209 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 265
Query: 922 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 978
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 266 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 318
Query: 979 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 1038
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 319 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 369
Query: 1039 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 1095
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 370 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 425
Query: 1096 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 1149
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 426 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 484
Query: 1150 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 1209
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 485 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 544
Query: 1210 NWISK 1214
+WI K
Sbjct: 545 SWIVK 549
Score = 33.9 bits (76), Expect = 0.98
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 78 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 137
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 138 KLALDELLQ 146
>gi|21245124 adenosine deaminase domain containing 1 (testis-specific)
isoform 1 [Homo sapiens]
Length = 576
Score = 136 bits (343), Expect = 1e-31
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
Query: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 861
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 173 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
Query: 862 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 921
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 227 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 283
Query: 922 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 978
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 284 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 336
Query: 979 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 1038
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 337 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 387
Query: 1039 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 1095
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 388 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 443
Query: 1096 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 1149
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 444 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 502
Query: 1150 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 1209
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 503 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 562
Query: 1210 NWISK 1214
+WI K
Sbjct: 563 SWIVK 567
Score = 33.9 bits (76), Expect = 0.98
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 126 bits (317), Expect = 1e-28
Identities = 142/542 (26%), Positives = 236/542 (43%), Gaps = 53/542 (9%)
Query: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
Query: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
Query: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 861
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 173 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
Query: 862 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 921
L LAA I+++ + VV++GTG D + G ++D HA + +RR
Sbjct: 227 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRS--- 280
Query: 922 FLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAM 981
L+ N + SIF L +K+ ++ LY++ P G + ++
Sbjct: 281 -----LLSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQ 328
Query: 982 ESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKIL 1041
FE ++ L VE G I + + DG+ R+ +MS SDK+
Sbjct: 329 LRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLT 379
Query: 1042 RWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHP 1098
RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 380 RWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMF 435
Query: 1099 FIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNE 1152
++VN P + V + + + K S+NW D LEI+DG G + +
Sbjct: 436 YLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSM 494
Query: 1153 LSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWI 1212
SR+ K + F L + L +Y AK + Y+ AK K L+ GYG+WI
Sbjct: 495 ASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWI 554
Query: 1213 SK 1214
K
Sbjct: 555 VK 556
Score = 33.9 bits (76), Expect = 0.98
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
Query: 563 MKAMTILLE 571
A+ LL+
Sbjct: 156 KLALDELLQ 164
>gi|223972690 adenosine deaminase domain containing 2 isoform 2 [Homo
sapiens]
Length = 583
Score = 115 bits (288), Expect = 3e-25
Identities = 137/501 (27%), Positives = 210/501 (41%), Gaps = 60/501 (11%)
Query: 731 LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 790
L EYA S G F+ DQ P P F A++ G PA A+SK + KQ+AA +AL
Sbjct: 120 LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
Query: 791 VLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHR 850
+ + E E + P+ S+ + T + A L
Sbjct: 178 YIRSQLENPESPQTSSRPPLAPLSVENIL-------------------THEQRCAALVSA 218
Query: 851 CFNTLTNSFQPSLLGRKILAAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKG 903
F+ L + P + +A +I++++ +++ +V+LGTG+ C G L G
Sbjct: 219 GFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSG 277
Query: 904 ETVNDCHAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHL 959
+ ++DCH +I+RR +RFL+ +L+ + + + S+ P G G +K V HL
Sbjct: 278 QQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHL 337
Query: 960 YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 1019
YIS P G + D + T P +P +L+ V + + +
Sbjct: 338 YISNTPKG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLC 387
Query: 1020 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTR 1078
T G +S SDK+ RW VLGL GALL H + P+Y S+ L L+R
Sbjct: 388 DTHVG--------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSR 439
Query: 1079 AICCRVTRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDL 1136
AI R D S L P++ H G + S+ + S+NW L D +
Sbjct: 440 AIHTRPCLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GI 496
Query: 1137 EILDGTRGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYET 1194
E++D G V + SR+ K + F + + LL L EA KA Y+
Sbjct: 497 EVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQE 555
Query: 1195 AKNYFKKGLKDMGYGNWISKP 1215
A+ L G G W SKP
Sbjct: 556 ARRQLSLLLDQQGLGAWPSKP 576
>gi|223972688 adenosine deaminase domain containing 2 isoform 1 [Homo
sapiens]
Length = 665
Score = 105 bits (261), Expect = 3e-22
Identities = 129/495 (26%), Positives = 202/495 (40%), Gaps = 70/495 (14%)
Query: 747 VDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTE 806
V++ GP F A++ G PA A+SK + KQ+AA +AL + + E E +
Sbjct: 208 VEELGPCFP--FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSS 265
Query: 807 VTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGR 866
P+ S+ + T + A L F+ L + P +
Sbjct: 266 RPPLAPLSVENIL-------------------THEQRCAALVSAGFDLLLDERSPYWACK 306
Query: 867 KILAAIIMKKD-----------------SEDMGVVVSLGTGNRCVKGDSLSLKGETVNDC 909
+A +I+++ +++ +V+LGTG+ C G L G+ ++DC
Sbjct: 307 GTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDC 365
Query: 910 HAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAP 965
H +I+RR +RFL+ +L+ + + + S+ P G G +K V HLYIS P
Sbjct: 366 HGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTP 425
Query: 966 CGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGI 1025
G + D + T P +P +L+ V + + + T G
Sbjct: 426 KG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG- 474
Query: 1026 RLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRV 1084
+S SDK+ RW VLGL GALL H + P+Y S+ L L+RAI R
Sbjct: 475 -------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRP 527
Query: 1085 TRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGT 1142
D S L P++ H G + S+ + S+NW L D +E++D
Sbjct: 528 CLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVA 584
Query: 1143 RGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFK 1200
G V + SR+ K + F + + LL L EA KA Y+ A+
Sbjct: 585 TGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLS 643
Query: 1201 KGLKDMGYGNWISKP 1215
L G G W SKP
Sbjct: 644 LLLDQQGLGAWPSKP 658
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 82.0 bits (201), Expect = 3e-15
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 37/221 (16%)
Query: 1028 GERLRTMSCSDKILRWNVLGLQGALLTHFL-QPIYLKSVTLGYL-FSQGHLTRAICCRVT 1085
G+R R+MSCSDK+ RWNVLG QGALL H L +PIYL +V +G +SQ + RA+ R
Sbjct: 291 GDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGR-C 349
Query: 1086 RDGSAFEDGLRHPFIVNHPKVGRVS-IYDSKRQSGKTKE-----------TSVNWCLADG 1133
++ SA G F V K+ + +++ R + + K +++W
Sbjct: 350 QNVSALPKG----FGVQELKILQSDLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPE 405
Query: 1134 YDLEIL-----DGTRGTVDGPRNELSRVSKKNIFLLFKKLCSFRYRRD----LLRL---- 1180
L++ GT G S++SK +F F+KL S R RD LR+
Sbjct: 406 QPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLS-RIARDKWPHSLRVQKLD 464
Query: 1181 SYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNF 1221
+Y E K+AA Y+ A + +K + +G+WI P + F
Sbjct: 465 TYQEYKEAASSYQEAWSTLRKQV----FGSWIRNPPDYHQF 501
Score = 64.7 bits (156), Expect = 5e-10
Identities = 35/111 (31%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 884 VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPA 943
+VS+GTG +C+ + G+ +ND HAE+I+RR F R+L +L + + +DSIF P
Sbjct: 61 IVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQL-QLAATLKEDSIFVPG 119
Query: 944 KGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFEN 994
++++ + F + S PCGD ++ +E + PVF N
Sbjct: 120 TQKGVWKLRRDLIFVFFSSHTPCGDASIIP------MLEFEDQPCCPVFRN 164
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 66 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 119
Query: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 120 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 178
Query: 767 RWFPAVCAHSKKQGKQEAA 785
R+ SKK K+ AA
Sbjct: 179 RFIEIGSGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 787 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 830
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 69 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 128
Query: 831 KTLP 834
P
Sbjct: 129 PVSP 132
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
Query: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 87 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 140
Query: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 141 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 199
Query: 767 RWFPAVCAHSKKQGKQEAA 785
R+ SKK K+ AA
Sbjct: 200 RFIEIGSGTSKKLAKRNAA 218
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 206 SGTSKKLAKRNAAAKMLLRVH 226
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
Query: 787 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 830
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 90 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 149
Query: 831 KTLP 834
P
Sbjct: 150 PVSP 153
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 65
Query: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 66 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 119
Query: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 120 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 178
Query: 767 RWFPAVCAHSKKQGKQEAA 785
R+ SKK K+ AA
Sbjct: 179 RFIEIGSGTSKKLAKRNAA 197
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 8 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 66
Query: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
A A+ L LE A S S S + A + TP PS S
Sbjct: 67 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 126
Query: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 127 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 184
Query: 661 SAPSKKVAKQMAAEEAMKALH 681
S SKK+AK+ AA + + +H
Sbjct: 185 SGTSKKLAKRNAAAKMLLRVH 205
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 10 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 68
Query: 787 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 830
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 69 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 128
Query: 831 KTLP 834
P
Sbjct: 129 PVSP 132
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 65.9 bits (159), Expect = 2e-10
Identities = 58/201 (28%), Positives = 96/201 (47%), Gaps = 30/201 (14%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
Query: 567 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 620
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
Query: 621 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
Query: 681 HGEATNSMASDNQPEGMISES 701
+ A++N+ + +I ++
Sbjct: 575 F---SGPNAANNKKKKIIPQA 592
Score = 61.6 bits (148), Expect = 4e-09
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 24/187 (12%)
Query: 623 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHG 682
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+ G
Sbjct: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAM-G 452
Query: 683 EATNSMA----------SDNQP--EGMISESLDN-----LESMMPNKVRKIGELVRYLNT 725
T A SDN+ E + S S +N E+ +VR G ++
Sbjct: 453 YPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK 512
Query: 726 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 785
NPV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 513 NPVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAA 567
Query: 786 DAALRVL 792
AAL L
Sbjct: 568 LAALEKL 574
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 63.2 bits (152), Expect = 2e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 L 680
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 745
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 746 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 63.2 bits (152), Expect = 2e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 L 680
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 745
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 746 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 63.2 bits (152), Expect = 2e-09
Identities = 55/181 (30%), Positives = 83/181 (45%), Gaps = 29/181 (16%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEKESEKTAESQTPTPSATSFFS------------------GKSPVTTL 619
S K E+S+ E E++ + P A S S GK+PV L
Sbjct: 476 SSKGEDSAE---ETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMEL 532
Query: 620 LECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKA 679
E L ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++
Sbjct: 533 NEKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEK 587
Query: 680 L 680
L
Sbjct: 588 L 588
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 33/234 (14%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMP-NKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFK 745
+ E++ + P + + G ++ NPV L E R +++
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR----GLKYE 542
Query: 746 LVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 595
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 62.4 bits (150), Expect = 3e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 734 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 794 GENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTL 833
E + + T G S+ + L++R AQ K L
Sbjct: 77 KEKKAVSPLLLTTTNSSEGLSMGNYIGLINRI--AQKKRL 114
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 683
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 684 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 740
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 741 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 795
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 3e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 734 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 794 GENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTL 833
E + + T G S+ + L++R AQ K L
Sbjct: 77 KEKKAVSPLLLTTTNSSEGLSMGNYIGLINRI--AQKKRL 114
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 683
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 684 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 740
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 741 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 795
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 62.4 bits (150), Expect = 3e-09
Identities = 32/65 (49%), Positives = 40/65 (61%)
Query: 511 YAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILL 570
Y Q ++ + SGPPH+ RF FQV+I+GREFP E SKK AK AA A+ IL
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 571 EEAKA 575
+E KA
Sbjct: 77 KEKKA 81
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 734 YARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Y + G +++ + SGPPH+ +F +Q + GR FP SKK+ K AA A+ +L
Sbjct: 17 YRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILN 76
Query: 794 GENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTL 833
E + + T G S+ + L++R AQ K L
Sbjct: 77 KEKKAVSPLLLTTTNSSEGLSMGNYIGLINRI--AQKKRL 114
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 30/175 (17%)
Query: 625 KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGE- 683
K G +++ L GP H+ +F + V + + FP SKK AK AA+ A++ L+ E
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEK 79
Query: 684 ---ATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGF 740
+ + + N EG+ S+ N ++ +K V Y
Sbjct: 80 KAVSPLLLTTTNSSEGL---SMGNYIGLINRIAQKKRLTVNYEQC--------------- 121
Query: 741 AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGE 795
SG F Y+ K+G + + +K++ KQ AA A ++ E
Sbjct: 122 --------ASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSE 168
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 61.6 bits (148), Expect = 4e-09
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 21/179 (11%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 621
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 622 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKL 592
Score = 57.4 bits (137), Expect = 8e-08
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 37/238 (15%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMPN-----KVRKIGELVRYLNTNPVGGLLEYARSHGFA 741
+ E++ + P+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 742 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 61.6 bits (148), Expect = 4e-09
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 21/179 (11%)
Query: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTI--LLEEAKAKD 577
++ ++ Q+GP H P F V ++G F A SKK AK A+K + L A+ +D
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD 475
Query: 578 SGKSEESSHYSTEK----------ESEKTAESQTPTPSATSFFSGKSPVTT------LLE 621
S K E+S+ + K E+ T + P+ + + P+ T ++E
Sbjct: 476 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME 535
Query: 622 CMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
+++ ++ L+S+ G +H+ +F V V Q F + +KKVAK AA A++ L
Sbjct: 536 -LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGS-NKKVAKAYAALAALEKL 592
Score = 57.4 bits (137), Expect = 8e-08
Identities = 57/238 (23%), Positives = 100/238 (42%), Gaps = 37/238 (15%)
Query: 582 EESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPA 641
EE S +K+ +K E P + + +++L +++L+S+ GP
Sbjct: 379 EEKSPSKKKKKIQKKEEKAEPPQAMNALMR-----------LNQLKPGLQYKLVSQTGPV 427
Query: 642 HEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL----HGEATNSMASDNQPE-- 695
H P F V V +F S PSKK AK A + ++ + E +S ++ E
Sbjct: 428 HAPIFTMSVEVDGNSF-EASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEET 486
Query: 696 ---------GMISESLDNLESMMPN-----KVRKIGELVRYLNTNPVGGLLEYARSHGFA 741
+ E++ + P+ V++ G ++ NPV L E R
Sbjct: 487 EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR----G 542
Query: 742 AEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKA 799
+++L+ ++G H+ +FV + +V G+ F +KK K AA AAL L + A
Sbjct: 543 LKYELISETGGSHDKRFVMEVEVDGQKFQG-AGSNKKVAKAYAALAALEKLFPDTPLA 599
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
Score = 44.7 bits (104), Expect = 6e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
Query: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
Query: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
+KK K+ AA+ L +L
Sbjct: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
Score = 39.7 bits (91), Expect = 0.018
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
Query: 781 KQEAADAALRVL 792
K+ AA A L L
Sbjct: 157 KKNAAIAVLEEL 168
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
Score = 44.7 bits (104), Expect = 6e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
Query: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 224 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 267
Query: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 268 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
Query: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
+KK K+ AA+ L +L
Sbjct: 328 HTAEGT-GTNKKVAKRNAAENMLEIL 352
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 40/209 (19%)
Query: 597 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 649
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
Query: 650 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLD 703
++VG Q F +++ AK AA +A++ L E PE + ++
Sbjct: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVN 172
Query: 704 NLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 763
ES N LN + + + E A F++ +SGPPH FV +
Sbjct: 173 GRESEEEN-----------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
Query: 764 VGGRWFPAVCAHSKKQGKQEAADAALRVL 792
V G + SKK K+ AA A L L
Sbjct: 222 V-GEFVGEGEGKSKKISKKNAAIAVLEEL 249
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 102 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 160
Query: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 161 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 212
Query: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 213 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 271
Score = 44.7 bits (104), Expect = 6e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 46 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 98
Query: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
KS ++ + E K F + + GP H F V+VG
Sbjct: 99 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 142
Query: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 143 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 186
Query: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 187 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
+KK K+ AA+ L +L
Sbjct: 247 HTAEGT-GTNKKVAKRNAAENMLEIL 271
Score = 39.7 bits (91), Expect = 0.018
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 38/192 (19%)
Query: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC-----------VAVGAQTFPSV 660
GK P+ ++ ++ ++ + + G A+ P++ Y ++VG Q F
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNG- 59
Query: 661 SAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVRKIGELV 720
+++ AK AA +A++ L E PE + ++ ES N
Sbjct: 60 KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVNGRESEEEN--------- 99
Query: 721 RYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQG 780
LN + + + E A F++ +SGPPH FV + V G + SKK
Sbjct: 100 --LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKIS 156
Query: 781 KQEAADAALRVL 792
K+ AA A L L
Sbjct: 157 KKNAAIAVLEEL 168
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,726,853
Number of Sequences: 37866
Number of extensions: 2488008
Number of successful extensions: 6683
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 6421
Number of HSP's gapped (non-prelim): 201
length of query: 1226
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1112
effective length of database: 13,930,794
effective search space: 15491042928
effective search space used: 15491042928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.