Guide to the Human Genome
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Name: PTGIS Sequence: fasta or formatted (500aa) NCBI GI: 13699859
Description:

prostaglandin I2 (prostacyclin) synthase

Referenced in:

Arachidonate, Prostaglandins, and Leukotrienes
Cytochrome P450 Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         41           2
 C cysteine            0.4          2           1
 D aspartate           6.0         30           1
 E glutamate           6.0         30           2
 F phenylalanine       4.6         23           1
 G glycine             5.8         29           2
 H histidine           3.4         17           1
 I isoleucine          2.6         13           1
 K lysine              3.8         19           2
 L leucine            16.6         83           7
 M methionine          2.8         14           1
 N asparagine          2.2         11           1
 P proline             5.6         28           2
 Q glutamine           3.0         15           1
 R arginine            7.8         39           3
 S serine              6.0         30           1
 T threonine           4.0         20           3
 V valine              5.8         29           3
 W tryptophan          2.0         10           1
 Y tyrosine            3.4         17           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   prostaglandin I2 (prostacyclin) synthase 
CYP8B1                0.357   cytochrome P450, family 8, subfamily B, polypeptide...
CYP7A1                0.237   cytochrome P450, family 7, subfamily A, polypeptide...
CYP7B1                0.221   cytochrome P450, family 7, subfamily B, polypeptide 1...
CYP39A1               0.082   cytochrome P450, family 39, subfamily A, polypeptide...
CYP51A1               0.036   cytochrome P450, family 51, subfamily A, polypeptide ...
CYP4F12               0.034   cytochrome P450, family 4, subfamily F, polypeptide...
CYP4V2                0.033   cytochrome P450, family 4, subfamily v, polypeptide...
CYP2U1                0.031   cytochrome P450, family 2, subfamily U, polypeptide ...
CYP3A43               0.031   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP4F2                0.030   cytochrome P450, family 4, subfamily F, polypeptide ...
CYP11B1               0.028   cytochrome P450, family 11, subfamily B, polypeptide...
CYP4A11               0.028   cytochrome P450, family 4, subfamily A, polypeptide...
CYP4F3                0.027   cytochrome P450, family 4, subfamily F, polypeptide...
CYP4F11               0.027   cytochrome P450 family 4 subfamily F polypeptide 11...
CYP4F11               0.027   cytochrome P450 family 4 subfamily F polypeptide 11...
CYP3A43               0.027   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP2C9                0.025   cytochrome P450, family 2, subfamily C, polypeptide ...
CYP2C19               0.025   cytochrome P450, family 2, subfamily C, polypeptide 1...
CYP2A7                0.024   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP2A7                0.024   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP4F8                0.024   cytochrome P450, family 4, subfamily F, polypeptide 8...
CYP2J2                0.024   cytochrome P450, family 2, subfamily J, polypeptide ...
CYP4A22               0.024   cytochrome P450, family 4, subfamily A, polypeptide ...
CYP11B2               0.022   cytochrome P450, family 11, subfamily B, polypeptid...
CYP2C8                0.022   cytochrome P450, family 2, subfamily C, polypeptide ...
CYP2S1                0.022   cytochrome P450, family 2, subfamily S, polypeptide ...
CYP3A5                0.022   cytochrome P450, family 3, subfamily A, polypeptide 5...
CYP24A1               0.021   cytochrome P450 family 24 subfamily A polypeptide 1 ...
CYP26A1               0.021   cytochrome P450, family 26, subfamily A, polypeptide...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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