Guide to the Human Genome
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Search of human proteins with 68226418

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68226418 glucose transporter protein 10 isoform b [Homo
sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]   989   0.0  
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]   973   0.0  
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...   971   0.0  
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...   389   e-108
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...   389   e-108
gi|4507013 solute carrier family 2 (facilitated glucose/fructose...   389   e-108
gi|134053883 intestinal facilitative glucose transporter 7 [Homo...   374   e-103
gi|166795299 solute carrier family 2 (facilitated glucose transp...   320   2e-87
gi|4507011 glucose transporter 4 [Homo sapiens]                       312   4e-85
gi|5902090 solute carrier family 2 (facilitated glucose transpor...   292   6e-79
gi|23592238 glucose transporter 14 [Homo sapiens]                     284   1e-76
gi|4557851 solute carrier family 2 (facilitated glucose transpor...   253   2e-67
gi|207447703 solute carrier family 2 (facilitated glucose/fructo...   179   5e-45
gi|21361449 solute carrier family 2 (facilitated glucose transpo...   125   1e-28
gi|223029432 solute carrier family 2 (facilitated glucose transp...   123   4e-28
gi|223029430 solute carrier family 2 (facilitated glucose transp...   117   3e-26
gi|203098995 solute carrier family 2 (facilitated glucose transp...    93   5e-19
gi|21553331 solute carrier family 2 (facilitated glucose transpo...    87   4e-17
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]           84   2e-16
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    61   2e-09
gi|170650643 solute carrier family 22, member 23 isoform a [Homo...    56   7e-08
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        55   1e-07
gi|166064021 solute carrier family 22 (organic anion transporter...    54   3e-07
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            54   3e-07
gi|4507005 solute carrier family 22 member 5 [Homo sapiens]            53   7e-07
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]          53   7e-07
gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]            52   1e-06
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa...    52   2e-06
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    52   2e-06
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]            49   1e-05

>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score =  989 bits (2557), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MLHALLRSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 60
           MLHALLRSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP
Sbjct: 1   MLHALLRSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 60

Query: 61  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 120
           LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK
Sbjct: 61  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 120

Query: 121 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 180
           AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG
Sbjct: 121 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 180

Query: 181 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 240
           LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG
Sbjct: 181 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 240

Query: 241 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 300
           DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS
Sbjct: 241 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 300

Query: 301 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 360
           SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV
Sbjct: 301 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 360

Query: 361 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 420
           ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI
Sbjct: 361 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 420

Query: 421 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 480
           MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP
Sbjct: 421 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 480

Query: 481 RRAQGPTWRSLEVIQSTEL 499
           RRAQGPTWRSLEVIQSTEL
Sbjct: 481 RRAQGPTWRSLEVIQSTEL 499


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score =  973 bits (2516), Expect = 0.0
 Identities = 490/491 (99%), Positives = 491/491 (100%)

Query: 9   RMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL 68
           R+IQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL
Sbjct: 6   RLIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL 65

Query: 69  MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 128
           MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM
Sbjct: 66  MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 125

Query: 129 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 188
           LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP
Sbjct: 126 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 185

Query: 189 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 248
           QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE
Sbjct: 186 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 245

Query: 249 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 308
           LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV
Sbjct: 246 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 305

Query: 309 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 368
           PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF
Sbjct: 306 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 365

Query: 369 PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLG 428
           PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLG
Sbjct: 366 PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLG 425

Query: 429 FPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTW 488
           FPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTW
Sbjct: 426 FPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTW 485

Query: 489 RSLEVIQSTEL 499
           RSLEVIQSTEL
Sbjct: 486 RSLEVIQSTEL 496


>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score =  971 bits (2511), Expect = 0.0
 Identities = 493/499 (98%), Positives = 493/499 (98%), Gaps = 1/499 (0%)

Query: 2   LHALLRSR-MIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 60
           L   LR R  IQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP
Sbjct: 5   LEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64

Query: 61  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 120
           LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK
Sbjct: 65  LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK 124

Query: 121 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 180
           AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG
Sbjct: 125 AGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG 184

Query: 181 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 240
           LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG
Sbjct: 185 LRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG 244

Query: 241 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 300
           DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS
Sbjct: 245 DLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYAS 304

Query: 301 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 360
           SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV
Sbjct: 305 SVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV 364

Query: 361 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 420
           ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI
Sbjct: 365 ALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWI 424

Query: 421 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 480
           MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP
Sbjct: 425 MLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFP 484

Query: 481 RRAQGPTWRSLEVIQSTEL 499
           RRAQGPTWRSLEVIQSTEL
Sbjct: 485 RRAQGPTWRSLEVIQSTEL 503


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score =  389 bits (1000), Expect = e-108
 Identities = 195/463 (42%), Positives = 289/463 (62%)

Query: 16  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
           LL+   A   G +F +GYNLS++NAPT +I+ F NE+W+ R G P+    + L+WS+ VS
Sbjct: 27  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 86

Query: 76  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
           ++ +GGL G L+   +   LGRK +LL NN F +SAA+L   S +AG+FEM+++GR ++G
Sbjct: 87  IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 146

Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
           ++ GV++++ PMYL E +PKE+RG++   +AIF  +G+  GQ++GL ELLG    WP L 
Sbjct: 147 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 206

Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
              +VP  +QL SLP LP+SPRYLL++  +    + A +   G  D++ E+EE+  E   
Sbjct: 207 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 266

Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315
            +  R     EL +   +R QV +++V  +  +LCG ++++ Y +S+F KAG+P AKI Y
Sbjct: 267 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 326

Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375
             + TG  E L AV S +VIE +GRR LLIGG+ LM  +    T+ L LQ   PW  YL+
Sbjct: 327 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 386

Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435
           +  I A I SF  GP G+  IL  E F Q  RPAA ++ G + W+    VGL FPFI ++
Sbjct: 387 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 446

Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478
           L  + ++ F  +C+ GAIY    LPETK +T+ EIS+   + N
Sbjct: 447 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489


>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score =  389 bits (1000), Expect = e-108
 Identities = 195/463 (42%), Positives = 289/463 (62%)

Query: 16  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
           LL+   A   G +F +GYNLS++NAPT +I+ F NE+W+ R G P+    + L+WS+ VS
Sbjct: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115

Query: 76  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
           ++ +GGL G L+   +   LGRK +LL NN F +SAA+L   S +AG+FEM+++GR ++G
Sbjct: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175

Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
           ++ GV++++ PMYL E +PKE+RG++   +AIF  +G+  GQ++GL ELLG    WP L 
Sbjct: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235

Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
              +VP  +QL SLP LP+SPRYLL++  +    + A +   G  D++ E+EE+  E   
Sbjct: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295

Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315
            +  R     EL +   +R QV +++V  +  +LCG ++++ Y +S+F KAG+P AKI Y
Sbjct: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355

Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375
             + TG  E L AV S +VIE +GRR LLIGG+ LM  +    T+ L LQ   PW  YL+
Sbjct: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415

Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435
           +  I A I SF  GP G+  IL  E F Q  RPAA ++ G + W+    VGL FPFI ++
Sbjct: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475

Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478
           L  + ++ F  +C+ GAIY    LPETK +T+ EIS+   + N
Sbjct: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518


>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score =  389 bits (999), Expect = e-108
 Identities = 202/472 (42%), Positives = 295/472 (62%), Gaps = 3/472 (0%)

Query: 10  MIQGRILLLTICA---AGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66
           M +GR+ L+   A   A  G +FQ+GYN++ +N+P L +Q+F NET+  RTGE + D  +
Sbjct: 8   MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPL 67

Query: 67  LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126
            L+WS+ VS++P GG  G+LL GPL    GRK +LL NNIF +  AIL G SR A SFE+
Sbjct: 68  TLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 127

Query: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186
           I++ RLLVG+ AGVS N+ PMYLGE APK LRGA+ +   +F  +GI++ Q+ GLR LL 
Sbjct: 128 IIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLA 187

Query: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGEL 246
               WP+LL    VP ALQL  LP  PESPRYLLI   D  A   AL+ LRG   +  E+
Sbjct: 188 NVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREV 247

Query: 247 EELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKA 306
            E+ +E  A +        +LF+ R+LR Q+ S++VL    +L G +++Y YA  ++  A
Sbjct: 248 AEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSA 307

Query: 307 GVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQS 366
           GVPE  +QY   GTG+  ++    +  V+E +GRR+LL+ G+S+      + T AL LQ 
Sbjct: 308 GVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQD 367

Query: 367 SFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVG 426
           +  W  Y+++ C+ ++++   +GP+ +  +L TE+F Q +RP+A MV G++ W+    VG
Sbjct: 368 TVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVG 427

Query: 427 LGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478
           L FPFI E L  + ++ F  +C+   IY  L +PETK KTF EI++   ++N
Sbjct: 428 LIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479


>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
           sapiens]
          Length = 512

 Score =  374 bits (959), Expect = e-103
 Identities = 199/472 (42%), Positives = 287/472 (60%), Gaps = 1/472 (0%)

Query: 7   RSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66
           R   +Q  +LL T+ AA  G  FQ+GYNLS++N P    + F NET+  R    +   L+
Sbjct: 15  REGRLQPTLLLATLSAA-FGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLM 73

Query: 67  LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126
           LL+WS  VS++PLGGL G+LL G L  + GRK +LL+NNIF +  AIL G S+ A +FE+
Sbjct: 74  LLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFEL 133

Query: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186
           I+  R+++GV AG+S +  PMYLGE APK LRG V   + +F  +G+ + Q+  L+ +LG
Sbjct: 134 IVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILG 193

Query: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGEL 246
            P  WP+LLA   VP  LQL +LP  PESPRY LI  GD      ALRRLRG  D+  EL
Sbjct: 194 NPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAEL 253

Query: 247 EELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKA 306
           E++  E  A +         L   R+LR Q+ S++VL +  +L G +++  YA +++  A
Sbjct: 254 EDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSA 313

Query: 307 GVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQS 366
           GV  A  QY  +G+G   ++  + S V++ER+GRR LL+ GY +      + TV L  Q+
Sbjct: 314 GVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQN 373

Query: 367 SFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVG 426
             P   YL + C+FA+I    IGP+ V  ++ TE+F Q +R AA MV GA+ W+   ++G
Sbjct: 374 RVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIG 433

Query: 427 LGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478
             FP I EA+  + ++ F G+C+  AIY  + +PETKGKTF EI++   + N
Sbjct: 434 FLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRN 485


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score =  320 bits (819), Expect = 2e-87
 Identities = 171/464 (36%), Positives = 264/464 (56%), Gaps = 4/464 (0%)

Query: 8   SRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVL 67
           S+ + GR++L       + G+ QFGYN  +INAP   I+EF N+TW  R GE +    + 
Sbjct: 5   SKKLTGRLMLAV--GGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLT 62

Query: 68  LMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 127
            +WSL V+++ +GG+ G+   G      GR+ S+L+ N+    +A+L GFS+   SFEM+
Sbjct: 63  TLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEML 122

Query: 128 MLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGG 187
           +LGR ++GV  G++    PMY+GE +P  LRGA+     +   +GI++ QV GL  ++G 
Sbjct: 123 ILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGN 182

Query: 188 PQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELE 247
              WPLLL+   +P  LQ   LP  PESPR+LLI+  +     + L++LRG+ D+  +L+
Sbjct: 183 KDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQ 242

Query: 248 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 307
           E++EE       +     ELF+  A R+ +   VVL  + +L G ++V+ Y++S+F KAG
Sbjct: 243 EMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAG 302

Query: 308 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSS 367
           V +    YA IG+G       VVS  V+ER GRR L + G + M     + T+AL L   
Sbjct: 303 VQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360

Query: 368 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 427
            PW  YL++  IF F+  F +GP  +   +  ELF Q  RPAA  V G   W    +VG+
Sbjct: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420

Query: 428 GFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEIS 471
            F ++ +    ++++ F  + V   I+T   +PETKG+TF EI+
Sbjct: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score =  312 bits (800), Expect = 4e-85
 Identities = 180/488 (36%), Positives = 276/488 (56%), Gaps = 15/488 (3%)

Query: 16  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTG----EPLPDHLVLLMWS 71
           L+L + +A +G + QFGYN+ +INAP   I++  NETW  R G      +P   +  +W+
Sbjct: 24  LVLAVFSAVLG-SLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWA 82

Query: 72  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131
           L V+++ +GG+  + L G ++  LGRK+++LVNN+  V    L G +  A S+EM++LGR
Sbjct: 83  LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142

Query: 132 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 191
            L+G  +G++  + PMY+GE AP  LRGA+   + +   +GI++ QV+GL  LLG    W
Sbjct: 143 FLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLW 202

Query: 192 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEE 251
           PLLL   ++P  LQL  LP  PESPRYL I          +L+RL G  D++G L EL++
Sbjct: 203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKD 262

Query: 252 ERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 311
           E+   +  R     +L   R  R+ +   VVL  + +L G ++V+ Y++S+F  AGV + 
Sbjct: 263 EKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQP 322

Query: 312 KIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWT 371
              YA IG G    +  +VS +++ER GRR L + G + M     + TVAL L    P  
Sbjct: 323 --AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAM 380

Query: 372 LYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPF 431
            Y+++  IF F+  F IGP  +   +  ELF Q  RPAA  V G   W    ++G+GF +
Sbjct: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440

Query: 432 IMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTWRSL 491
           + EA+  ++++ F  + +   I+T L +PET+G+TF +IS   HR         P+    
Sbjct: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRT--------PSLLEQ 492

Query: 492 EVIQSTEL 499
           EV  STEL
Sbjct: 493 EVKPSTEL 500


>gi|5902090 solute carrier family 2 (facilitated glucose
           transporter), member 3 [Homo sapiens]
          Length = 496

 Score =  292 bits (747), Expect = 6e-79
 Identities = 161/457 (35%), Positives = 258/457 (56%), Gaps = 3/457 (0%)

Query: 16  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
           L+  I  A IG +FQFGYN  +INAP   I+EF N+T   +   P  + L+  +WSL V+
Sbjct: 10  LIFAITVATIG-SFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVA 68

Query: 76  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
           ++ +GG+ G+   G      GR+ S+L+ N+  V+     G  + A S EM++LGRL++G
Sbjct: 69  IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128

Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
           +  G+     PMY+GE +P  LRGA    + +   +GI++ Q+ GL  +LG  + WPLLL
Sbjct: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188

Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
              ++P  LQ A+LP  PESPR+LLI+  + E     L+RL G+ D++ +++E+++E A 
Sbjct: 189 GFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESAR 248

Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315
               +     ELF+  + R+ +   +VL  + +L G ++V+ Y++ +F+ AGV E    Y
Sbjct: 249 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IY 306

Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375
           A IG G    +  VVS  ++ER GRR L + G   M    ++ TV+L L+ ++    ++ 
Sbjct: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366

Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435
           +  I  F+  F IGP  +   +  ELF Q  RPAA  V G   W    LVGL FP     
Sbjct: 367 IGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHY 426

Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 472
           L  ++++ F G  +    +T   +PET+G+TF++I++
Sbjct: 427 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 463


>gi|23592238 glucose transporter 14 [Homo sapiens]
          Length = 520

 Score =  284 bits (726), Expect = 1e-76
 Identities = 156/457 (34%), Positives = 256/457 (56%), Gaps = 3/457 (0%)

Query: 16  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
           L+  I  A IG +FQFGYN  +INAP   I+EF N+T   +   P  + L+  +WSL V+
Sbjct: 34  LIFAITVATIG-SFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVA 92

Query: 76  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
           ++ +GG+ G+   G      GR+ S+L+ N+   +   L G  + A S EM++LGRL++G
Sbjct: 93  IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIG 152

Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
           +  G+     PMY+GE +P  LRGA    + +   +GI++ Q+ GL  +LG  + WP+LL
Sbjct: 153 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLL 212

Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
              ++P  LQ A+LP  PESPR+LLI+    E     L+RL G+ D++ +++E+++E A 
Sbjct: 213 GFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESAR 272

Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315
               +     ELF+  + R+ +   +VL  + +L G ++V+ Y++ +F+ AGV +    Y
Sbjct: 273 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQP--IY 330

Query: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375
           A I  G    +  ++S  ++ER GRR L + G   M    ++ TV+L L++ +    ++ 
Sbjct: 331 ATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVC 390

Query: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435
           +  I  F+  F IGP  +   +  ELF Q  RPAA  V G   W    LVGL FP     
Sbjct: 391 IGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYY 450

Query: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 472
           L  ++++ F G  +    +T   +PET+G+TF++I++
Sbjct: 451 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 487


>gi|4557851 solute carrier family 2 (facilitated glucose
           transporter), member 2 [Homo sapiens]
          Length = 524

 Score =  253 bits (647), Expect = 2e-67
 Identities = 157/499 (31%), Positives = 249/499 (49%), Gaps = 45/499 (9%)

Query: 16  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDH----------- 64
           L+ T+  A +G +FQFGY++ +INAP    Q+     ++   G PL D            
Sbjct: 10  LVFTVITAVLG-SFQFGYDIGVINAP----QQVIISHYRHVLGVPLDDRKAINNYVINST 64

Query: 65  ---------------------------LVLLMWSLIVSLYPLGGLFGALLAGPLAITLGR 97
                                      L+ ++WSL VS + +GG+  +   G L  TLGR
Sbjct: 65  DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124

Query: 98  KKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKEL 157
            K++LV NI  +  A+L GFS+   S  +I+ GR + G+  G+   + PMY+GE AP  L
Sbjct: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184

Query: 158 RGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPR 217
           RGA+     +    GI++ Q++GL  +LG    W +LL    V   LQ   L   PESPR
Sbjct: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244

Query: 218 YLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQV 277
           YL I   +      +L+RLRG  D+  ++ E+ +ER      +     +LF + + R+ +
Sbjct: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304

Query: 278 TSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIER 337
              ++L  A +  G + ++ Y++S+F+ AG+  +K  YA IG G+  ++   VS  ++E+
Sbjct: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVEK 362

Query: 338 VGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGIL 397
            GRR L + G S M       +V L L + F W  Y++M  IF F+  F IGP  +   +
Sbjct: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422

Query: 398 ATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGL 457
             E F Q  RPAA  +     W    +V L F +I +    +++  F GV +   ++T  
Sbjct: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482

Query: 458 FLPETKGKTFQEISKELHR 476
            +PETKGK+F+EI+ E  +
Sbjct: 483 KVPETKGKSFEEIAAEFQK 501


>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 244

 Score =  179 bits (454), Expect = 5e-45
 Identities = 91/179 (50%), Positives = 124/179 (69%), Gaps = 3/179 (1%)

Query: 10  MIQGRILLLTICA---AGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66
           M +GR+ L+   A   A  G +FQ+GYN++ +N+P L +Q+F NET+  RTGE + D  +
Sbjct: 8   MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPL 67

Query: 67  LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126
            L+WS+ VS++P GG  G+LL GPL    GRK +LL NNIF +  AIL G SR A SFE+
Sbjct: 68  TLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 127

Query: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELL 185
           I++ RLLVG+ AGVS N+ PMYLGE APK LRGA+ +   +F  +GI++ Q+ GLR LL
Sbjct: 128 IIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLL 186


>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score =  125 bits (313), Expect = 1e-28
 Identities = 129/491 (26%), Positives = 213/491 (43%), Gaps = 72/491 (14%)

Query: 12  QGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLP--DHLVLLM 69
           +GR + L   AA +G    FG+ L   +     +Q         R   P P  D      
Sbjct: 22  RGRRVFLAAFAAALG-PLSFGFALGYSSPAIPSLQ---------RAAPPAPRLDDAAASW 71

Query: 70  WSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNI-FVVSAAILFGFSRKAGSFEMIM 128
           +  +V+L   G   G +L G L    GRK SLL+ ++ FV   A++      A    M++
Sbjct: 72  FGAVVTL---GAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA----AQDVWMLL 124

Query: 129 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 188
            GRLL G+  GV+  + P+Y+ E A   +RG +     +   +GI+      L  L G  
Sbjct: 125 GGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL------LAYLAGWV 178

Query: 189 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 248
             W  L     VP +L L  +  +PE+PR+LL      EA +AALR L GS +   E   
Sbjct: 179 LEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA-MAALRFLWGS-EQGWEDPP 236

Query: 249 LEEERAACQGCRARRPWELFQHRALRRQ--VTSLVVLGSAM----ELCGNDSVYAYASSV 302
           +  E++               H AL RQ  +    ++G ++    +L G ++V  YA ++
Sbjct: 237 IGAEQSF--------------HLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETI 282

Query: 303 FRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVAL 362
           F +A   ++ +   ++G    ++L   V+ ++++R GRR+LL+    +M    S F    
Sbjct: 283 FEEAKFKDSSLASVVVGV--IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYF 340

Query: 363 CLQSSFPWT---------------------LYLAMACIFAFILSFGIGPAGVTGILATEL 401
            L    P                        +LA+  +  FI  F +G   +  +L +E+
Sbjct: 341 KLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEI 400

Query: 402 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLP 460
           F    +  A  +C    W+M  LV   F  +ME L  +  +      C+   ++T   +P
Sbjct: 401 FPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVP 460

Query: 461 ETKGKTFQEIS 471
           ETKGKT ++I+
Sbjct: 461 ETKGKTLEQIT 471


>gi|223029432 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 1 [Homo sapiens]
          Length = 507

 Score =  123 bits (308), Expect = 4e-28
 Identities = 128/492 (26%), Positives = 215/492 (43%), Gaps = 69/492 (14%)

Query: 14  RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 72
           R+ L T  A  + G F FGY L +  +P +   E + +          PD HL     S 
Sbjct: 37  RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83

Query: 73  IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 130
             S++ LG   G L A  L   LGRK S++ +   V SAA   G++  AG+    M++LG
Sbjct: 84  FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138

Query: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 190
           R L G   G++    P+Y+ E AP  +RGA+  +  +    G +    +GL  LL     
Sbjct: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192

Query: 191 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 249
           W  L  +   P  + +  L  +P SPR+LL    D EA L AL  LRG+  D+  E E++
Sbjct: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251

Query: 250 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 309
           ++     +   +R  W   +   + R +T  +++    +L G   +  Y  S+F    V 
Sbjct: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308

Query: 310 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM------------------ 351
                 A I  G+  LL+ +++ + ++  GR+VLL    ++M                  
Sbjct: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPL 367

Query: 352 ----------TCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATEL 401
                       WG +   A  L +   +   + +     FI+ + +G   +T +L +E+
Sbjct: 368 SPNSTAGLESESWGDL---AQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEV 424

Query: 402 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFL---GVCVCGAIYTGLF 458
               AR  A  +C    W+   ++   F  ++      L VPF     +C+   ++TG  
Sbjct: 425 LPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFG--LQVPFFFFAAICLVSLVFTGCC 482

Query: 459 LPETKGKTFQEI 470
           +PETKG++ ++I
Sbjct: 483 VPETKGRSLEQI 494


>gi|223029430 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 2 [Homo sapiens]
          Length = 445

 Score =  117 bits (292), Expect = 3e-26
 Identities = 122/464 (26%), Positives = 202/464 (43%), Gaps = 75/464 (16%)

Query: 14  RILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPD-HLVLLMWSL 72
           R+ L T  A  + G F FGY L +  +P +   E + +          PD HL     S 
Sbjct: 37  RVFLATFAA--VLGNFSFGYAL-VYTSPVIPALERSLD----------PDLHLTKSQASW 83

Query: 73  IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFE--MIMLG 130
             S++ LG   G L A  L   LGRK S++ +   V SAA   G++  AG+    M++LG
Sbjct: 84  FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSA--VPSAA---GYALMAGAHGLWMLLLG 138

Query: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQA 190
           R L G   G++    P+Y+ E AP  +RGA+  +  +    G +    +GL  LL     
Sbjct: 139 RTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----P 192

Query: 191 WPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELEEL 249
           W  L  +   P  + +  L  +P SPR+LL    D EA L AL  LRG+  D+  E E++
Sbjct: 193 WRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEA-LRALAWLRGTDVDVHWEFEQI 251

Query: 250 EEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVP 309
           ++     +   +R  W   +   + R +T  +++    +L G   +  Y  S+F    V 
Sbjct: 252 QDN---VRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVL 308

Query: 310 EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFP 369
                 A I  G+  LL+ +++ + ++  GR+VLL                         
Sbjct: 309 LPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL------------------------- 342

Query: 370 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 429
                       F+  + +G   +T +L +E+    AR  A  +C    W+   ++   F
Sbjct: 343 ------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390

Query: 430 PFIMEALSHFLYVPFL---GVCVCGAIYTGLFLPETKGKTFQEI 470
             ++      L VPF     +C+   ++TG  +PETKG++ ++I
Sbjct: 391 LPVVSTFG--LQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432


>gi|203098995 solute carrier family 2 (facilitated glucose
           transporter), member 13 [Homo sapiens]
          Length = 648

 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 80/325 (24%), Positives = 140/325 (43%), Gaps = 24/325 (7%)

Query: 27  GTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVSLYPLGGLFGAL 86
           G F FGY+  +++   L ++   +              L  L   L+VS         AL
Sbjct: 91  GGFLFGYDTGVVSGAMLLLKRQLS--------------LDALWQELLVSSTVGAAAVSAL 136

Query: 87  LAGPLAITLGRKKS-LLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQ 145
             G L    GR+ + LL + +F   +A+L   + K    E ++ GRL+VG+  G++    
Sbjct: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVGLGIGIASMTV 192

Query: 146 PMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQ 205
           P+Y+ E +P  LRG +   + +F   G     VV           W  +L    VP  +Q
Sbjct: 193 PVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQ 252

Query: 206 LASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELE---EERAACQGCRAR 262
                 LPESPR+ LI  G T+     L ++RG+  +  E + ++   EE     G    
Sbjct: 253 FFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP 311

Query: 263 RPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIG-TG 321
               +  +   RR +     L    +L G +++  Y++++ + +GV + ++   +   T 
Sbjct: 312 VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTA 371

Query: 322 SCELLTAVVSCVVIERVGRRVLLIG 346
               +  +V   ++E+VGRR L  G
Sbjct: 372 FTNFIFTLVGVWLVEKVGRRKLTFG 396



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 368 FPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGL 427
           + WT  L +     F    G+GP   T  + +E++   AR         + WI  +LV L
Sbjct: 505 YSWTALLGLILYLVFFAP-GMGPMPWT--VNSEIYPLWARSTGNACSSGINWIFNVLVSL 561

Query: 428 GFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLPETKGKTFQEI 470
            F    E L+++  +  + G    G ++    LPETKGK  +EI
Sbjct: 562 TFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 75/341 (21%), Positives = 152/341 (44%), Gaps = 25/341 (7%)

Query: 13  GRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSL 72
           G    L+   A + G    GY L II+   L I+     +   +               +
Sbjct: 37  GMFTFLSSVTAAVSGLL-VGYELGIISGALLQIKTLLALSCHEQ--------------EM 81

Query: 73  IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRL 132
           +VS   +G L  +L  G L    GR+ ++++++  +   +++   S    S+ ++++GR+
Sbjct: 82  VVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRI 138

Query: 133 LVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWP 192
            +GV+  +S     +Y+ E AP+  RG +   + +   +GI+   +            W 
Sbjct: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWK 197

Query: 193 LLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEE 252
            +    +  G LQ  ++  LP SPR+L++  G   A    L RLR   D     EEL   
Sbjct: 198 YMFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTT---EELTVI 253

Query: 253 RAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 311
           +++ +       W+LF+ +  +R ++   + L   +++ G  ++  YAS+V +  G    
Sbjct: 254 KSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSN 313

Query: 312 K-IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 351
           +    A  G G  ++++ + + ++++ VG +  L  G S+M
Sbjct: 314 EAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM 354



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 7/111 (6%)

Query: 373 YLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFI 432
           +L++A +  ++ +F IG   +  ++ +E+F    R  A  +  ++ W + +L+ L F  +
Sbjct: 462 WLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTV 521

Query: 433 MEALSH----FLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479
            + +      F+Y     + +   ++  +F+PETKG + ++IS EL ++N+
Sbjct: 522 TDLIGLPWVCFIYTI---MSLASLLFVVMFIPETKGCSLEQISMELAKVNY 569


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 90/339 (26%), Positives = 145/339 (42%), Gaps = 42/339 (12%)

Query: 17  LLTICAA-GIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
           +L +CA+  + G   FGY L++I+   L +Q              L   L  L    +V 
Sbjct: 7   VLPLCASVSLLGGLTFGYELAVISGALLPLQ--------------LDFGLSCLEQEFLVG 52

Query: 76  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
              LG L  +L+ G L    GRK+++L +N+ +++ ++  G    AGS   ++LGR +VG
Sbjct: 53  SLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVVG 109

Query: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
               +S     +Y+ E      RG +         +GI++   +    L G P  W  + 
Sbjct: 110 FAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRHMF 168

Query: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
                P  LQ  SL  LP           D  A    L  L+G     GE  +L   R  
Sbjct: 169 GWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG-----GEAPKLGPGRPR 215

Query: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAM--ELCGNDSVYAYASSVFRKAGVPE-AK 312
                     +LF+ R   R  T+ V LG  +  +L G  +V  YAS++F   G    + 
Sbjct: 216 YSFL------DLFRARDNMRGRTT-VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSS 268

Query: 313 IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 351
              A +G G+ ++   + +  +++R GRR LL+ G +LM
Sbjct: 269 AVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 8/113 (7%)

Query: 370 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 429
           WT   A+ C+  F+ +F  G   VT ++ +E++    R  A   C +  W   + + L F
Sbjct: 410 WT---ALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSF 466

Query: 430 PFIMEALS---HFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479
             ++  +     FL      V   G IY  LF+PETKG++  EI ++  +  F
Sbjct: 467 LDLIGTIGLSWTFLLYGLTAVLGLGFIY--LFVPETKGQSLAEIDQQFQKRRF 517


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 103/410 (25%), Positives = 167/410 (40%), Gaps = 32/410 (7%)

Query: 72  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131
           L  S    G LFG+L  G  A   GRK  LL   +    + +L  FS    ++  ++L R
Sbjct: 150 LFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSMLLFR 206

Query: 132 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 191
           LL G+ +  +       + E      R  VA+   +   +G+V   + GL   L     W
Sbjct: 207 LLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLV--ALTGLAYAL---PHW 261

Query: 192 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDL-AGELEELE 250
             L  +  +P  L L     +PESPR+LL    +TEA        + +G L   +L+ L 
Sbjct: 262 RWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLS 321

Query: 251 EERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPE 310
            E    +        +LF+   LR++   L      M L   DSV      +    G   
Sbjct: 322 LEEDVTEKLSPSFA-DLFRTPRLRKRTFIL------MYLWFTDSV--LYQGLILHMGATS 372

Query: 311 AKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPW 370
             +    + +   E+  A ++ + I+RVG R+  +   +L+   G+   V + +     W
Sbjct: 373 GNLYLDFLYSALVEIPGAFIALITIDRVG-RIYPMAMSNLLA--GAACLVMIFISPDLHW 429

Query: 371 TLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFP 430
            L + + C+    ++  I    +  ++  EL+    R    MVC +L  I     G+  P
Sbjct: 430 -LNIIIMCVGRMGITIAI---QMICLVNAELYPTFVRNLGVMVCSSLCDI----GGIITP 481

Query: 431 FIMEALSH-FLYVPFLGVCVCGAIYTG--LFLPETKGKTFQEISKELHRL 477
           FI+  L   +  +P +   V G +  G  L LPETKG    E  K+   L
Sbjct: 482 FIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENL 531


>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
           sapiens]
          Length = 686

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 99/431 (22%), Positives = 172/431 (39%), Gaps = 60/431 (13%)

Query: 70  WSLIVSLYPL--GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMI 127
           W + ++ + L  G +FG L+ G +A  +GR+  LL + IF++   +    S     F  +
Sbjct: 227 WKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTL 286

Query: 128 MLGRLLVG-VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186
              R   G   AG+ + +  + + E  P   R  + M ++     G  +  + GL  L  
Sbjct: 287 ---RFFEGFCLAGIILTLYALRI-ELCPPGKRFMITMVASFVAMAGQFL--MPGLAALC- 339

Query: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL-----RRLRGSGD 241
             + W +L A  + P  L L    + PES R+L+       A    L      R+   GD
Sbjct: 340 --RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD 397

Query: 242 LAGELEELEEERAACQGCRARRPWELFQHRAL-RRQVTSLVVLGSAMELCGNDSVYAYAS 300
           + G + ELE+E        +RRP ++   + +  R +   +V+     L G    + +A 
Sbjct: 398 IKGVIPELEKE-------LSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFAR 450

Query: 301 SVF-RKAGVPEAKIQYA-IIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIF 358
           S+   +  VP  +  YA    T S  L++ +  CVV+  +GRR  L+  + ++T   S+ 
Sbjct: 451 SMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLL-LFMILTALASLL 509

Query: 359 TVALC-------------LQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQM 405
            + L              +  S      +A + +  F  S  +G   V      E+   +
Sbjct: 510 QLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMF-ASHAVGSLSV--FFCAEITPTV 566

Query: 406 ARPAACMVCGALMWIMLILVGLGFPFIMEAL-------SHFLYVPFLGVCVCGAIYTGLF 458
            R      CG L    L+L   GF  +   +        +FL+      C    I   L 
Sbjct: 567 IR------CGGL---GLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILL 617

Query: 459 LPETKGKTFQE 469
           LPE++ +   E
Sbjct: 618 LPESRDQNLPE 628


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 46/167 (27%), Positives = 84/167 (50%), Gaps = 9/167 (5%)

Query: 71  SLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLG 130
           +L+ ++   G +  ++L G LA   GR K LL++ ++    ++L  F   A S+   +  
Sbjct: 87  ALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSF---APSYIWFVFL 143

Query: 131 RLLVGVNAGVSMNIQPMYLG-ESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQ 189
           R +VG   GVS + Q + +  E  P + RG +   S +F   G ++  ++GL  ++    
Sbjct: 144 RTMVG--CGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTI 199

Query: 190 AWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRL 236
            W  L+    +PG + + +   +PES R+  +  G+T A LA L R+
Sbjct: 200 GWRWLIRVASIPGIILIVAFKFIPESARF-NVSTGNTRAALATLERV 245


>gi|166064021 solute carrier family 22 (organic anion transporter),
           member 13 [Homo sapiens]
          Length = 551

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 101/422 (23%), Positives = 172/422 (40%), Gaps = 57/422 (13%)

Query: 75  SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 134
           S++  G L G L+ GPL   +GRK ++L   +      +   F     SFE+ M  R  V
Sbjct: 142 SVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAF---VPSFELYMALRFAV 198

Query: 135 GVN-AGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPL 193
               AG+S +   +      P     AV ++   F+     +GQ+V L  L  G + W L
Sbjct: 199 ATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFS-----LGQMV-LAGLAYGFRNWRL 252

Query: 194 LLASCLVPGALQLASLPLLPESPRYLLIDCGDTEAC-----LAALRRLRGSGDLAGELEE 248
           L  +   PG L       LPES R+LL      EA       A++ R + S +L   + +
Sbjct: 253 LQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPEL---MNQ 309

Query: 249 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 308
           L  E+    G       +LF+H  LR+ VT ++       +   DS+  Y  S+  + G 
Sbjct: 310 LVPEKTGPSG----NALDLFRHPQLRK-VTLIIFC-----VWFVDSLGYYGLSL--QVGD 357

Query: 309 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 368
               +    +  G+ E+     S  +++R GR+   +G    +   G +  + + + +  
Sbjct: 358 FGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLG---TLVLGGLMCIIIIFIPADL 414

Query: 369 PWTLYL-----AMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLI 423
           P  + +      MA   AF +S+         + + ELF  + R         L+ I   
Sbjct: 415 PVVVTMLAVVGKMATAAAFTISY---------VYSAELFPTILRQTGM----GLVGIFSR 461

Query: 424 LVGLGFPFIMEALSHFLYVPFLGV----CVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479
           + G+  P ++    +   +P L       V G + T   LPET G+  ++  ++L     
Sbjct: 462 IGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCT--LLPETHGQGLKDTLQDLELGPH 519

Query: 480 PR 481
           PR
Sbjct: 520 PR 521


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 88/420 (20%), Positives = 168/420 (40%), Gaps = 36/420 (8%)

Query: 69  MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 128
           M  L  S   +G   G++  G +A   GRK  LL   +   +A +L   S    ++  ++
Sbjct: 148 MLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISP---TYTWML 204

Query: 129 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 188
           + RL+ G+ +     I  + + E   +  R  V +   +   +G+++  + G+   L   
Sbjct: 205 IFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLV--LAGVAYAL--- 259

Query: 189 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSG-DLAGELE 247
             W  L  +  +P    L     +PESPR+L+    + EA        + +G  L   L+
Sbjct: 260 PHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQ 319

Query: 248 ELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAG 307
            L  E    +  +   P  L   R  + +  +++++ +        S   Y   +    G
Sbjct: 320 RLRLEE---ETGKKLNPSFLDLVRTPQIRKHTMILMYNWFT-----SSVLYQGLIMHM-G 370

Query: 308 VPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM--TCWGSIFTVALCLQ 365
           +    I      +   E   A +  + I+R+GRR        +    C  S+F     + 
Sbjct: 371 LAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVF-----IP 425

Query: 366 SSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILV 425
               W L + ++C+    ++       +  ++  EL+    R     +C +    M  + 
Sbjct: 426 GDLQW-LKIIISCLGRMGITMAYE---IVCLVNAELYPTFIRNLGVHICSS----MCDIG 477

Query: 426 GLGFPFIMEALSH-FLYVPFLGVCVCGAIYTGL--FLPETKGKTFQEISKELHRLNFPRR 482
           G+  PF++  L++ +L +P +   V G +  GL   LPETKGK   E  +E   +  PR+
Sbjct: 478 GIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRK 537


>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
          Length = 557

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 100/435 (22%), Positives = 181/435 (41%), Gaps = 60/435 (13%)

Query: 72  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131
           L +SL+ +G L G+ ++G L+   GRK  L V        + L  FS+   +FEM ++  
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSK---NFEMFVVLF 200

Query: 132 LLVGVNAGVSMNIQPMYLG-ESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP-- 188
           +LVG+   +S  +    LG E   K +R        IF+ LG+ +    G   L   P  
Sbjct: 201 VLVGMGQ-ISNYVAAFVLGTEILGKSVR-------IIFSTLGVCIFYAFGYMVL---PLF 249

Query: 189 ----QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLA- 243
               + W +LL +  +PG L +A    +PESPR+L+      EA +   +  + +G +  
Sbjct: 250 AYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVP 309

Query: 244 ------GELEELEEERAACQG-CRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVY 296
                  EL++L  ++          R W +       R VT + ++     L    SV 
Sbjct: 310 STIFDPSELQDLSSKKQQSHNILDLLRTWNI-------RMVTIMSIM-----LWMTISVG 357

Query: 297 AYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGS 356
            +  S+          I      +   E+   V++ ++++ + RR      YS+ T    
Sbjct: 358 YFGLSL--DTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRR------YSMATALFL 409

Query: 357 IFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPA-GVTGILATELFDQMARPAACMVCG 415
             +V L +Q   P   YL  A +   +  FG+  A  +  +   EL+  + R     V  
Sbjct: 410 GGSVLLFMQLVPPDLYYL--ATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSS 467

Query: 416 ALMWIMLILVGLGFPFIMEALSHFLYVPFL---GVCVCGAIYTGLFLPETKGKTFQEISK 472
               +  IL     P+ +   ++  ++P++    + +  AI T LFLPE+ G    +   
Sbjct: 468 TASRLGSIL----SPYFVYLGAYDRFLPYILMGSLTILTAILT-LFLPESFGTPLPDTID 522

Query: 473 ELHRLNFPRRAQGPT 487
           ++ R+   +  + P+
Sbjct: 523 QMLRVKGMKHRKTPS 537


>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
          Length = 683

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 14/153 (9%)

Query: 79  LGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNA 138
           LG + GA + G LA  LGRK+ L ++     S A L  F +  G+F   +  RL+ G+  
Sbjct: 156 LGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAF---LFCRLISGIGI 212

Query: 139 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLRELLGGP-- 188
           G ++ I   Y  E   +E RG       IF   G +    +        G    +G    
Sbjct: 213 GGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYH 272

Query: 189 -QAWPLLLASCLVPGALQLASLPLLPESPRYLL 220
             +W + +  C +P  + + +L  +PESPR+LL
Sbjct: 273 FHSWRVFVIVCALPCTVSMVALKFMPESPRFLL 305


>gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]
          Length = 742

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 47/157 (29%), Positives = 70/157 (44%), Gaps = 22/157 (14%)

Query: 79  LGGLFGALLAGPLAITLGRKKSLL----VNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 134
           LG + GA L G LA  LGR++ LL    VN++F   ++ + G+    G+F   +  RLL 
Sbjct: 213 LGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGY----GTF---LFCRLLS 265

Query: 135 GVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLRELLG 186
           GV  G S+ I   Y  E   +E RG       +F  +G V    +        G    +G
Sbjct: 266 GVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMG 325

Query: 187 GP---QAWPLLLASCLVPGALQLASLPLLPESPRYLL 220
                 +W + +  C  P    + +L   PESPR+ L
Sbjct: 326 SAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFL 362


>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
           sapiens]
          Length = 548

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 103/423 (24%), Positives = 164/423 (38%), Gaps = 57/423 (13%)

Query: 80  GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG-VNA 138
           G L GA+  G L+   GR++ LLV     VS  +L   S  + S+ M  + R L G   A
Sbjct: 154 GVLVGAVAFGYLSDRFGRRRLLLVA---YVSTLVLGLASAASVSYVMFAITRTLTGSALA 210

Query: 139 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG--LRELLGGPQAWPLLLA 196
           G ++ + P+ L E    E R    + S+ F   G+++  +VG  +R+       W  LL 
Sbjct: 211 GFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD-------WRWLLL 262

Query: 197 SCLVPGALQLASLPLLPESPRYLLIDCGDTEA--CLAALRRLRGSGDLAGELEELEEERA 254
           +  +P A  + SL  +PES R+LL      EA   L    RL G         +    + 
Sbjct: 263 AVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKV 322

Query: 255 ACQGCRARRP--WELFQHRALRRQVTSLVVL---------GSAMELCGNDSVYAYASSVF 303
           A      RRP   +LF+   LR      VV+         G ++++ G          +F
Sbjct: 323 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLF 382

Query: 304 RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV-AL 362
               +P   + Y  +      L  A          G R+L+    S M  W ++  V   
Sbjct: 383 GAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLV---SSDMKSWSTVLAVMGK 439

Query: 363 CLQSSFPWTLYLAMACIFAFIL-SFGIGPAGVTGILATELFDQMARPAACMVCGALMWIM 421
               +   T YL  + ++  +L   G+G   + G L   L      P A ++ G  +W+ 
Sbjct: 440 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSL-----APLAALLDG--VWLS 492

Query: 422 LILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPR 481
           L  +  G                 G+ +  A  T L LPET+     E  +++ R + P 
Sbjct: 493 LPKLTYG-----------------GIALLAA-GTALLLPETRQAQLPETIQDVERKSAPT 534

Query: 482 RAQ 484
             Q
Sbjct: 535 SLQ 537


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 103/423 (24%), Positives = 164/423 (38%), Gaps = 57/423 (13%)

Query: 80  GGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG-VNA 138
           G L GA+  G L+   GR++ LLV     VS  +L   S  + S+ M  + R L G   A
Sbjct: 152 GVLVGAVAFGYLSDRFGRRRLLLVA---YVSTLVLGLASAASVSYVMFAITRTLTGSALA 208

Query: 139 GVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG--LRELLGGPQAWPLLLA 196
           G ++ + P+ L E    E R    + S+ F   G+++  +VG  +R+       W  LL 
Sbjct: 209 GFTIIVMPLEL-EWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRD-------WRWLLL 260

Query: 197 SCLVPGALQLASLPLLPESPRYLLIDCGDTEA--CLAALRRLRGSGDLAGELEELEEERA 254
           +  +P A  + SL  +PES R+LL      EA   L    RL G         +    + 
Sbjct: 261 AVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKV 320

Query: 255 ACQGCRARRP--WELFQHRALRRQVTSLVVL---------GSAMELCGNDSVYAYASSVF 303
           A      RRP   +LF+   LR      VV+         G ++++ G          +F
Sbjct: 321 AAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLF 380

Query: 304 RKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTV-AL 362
               +P   + Y  +      L  A          G R+L+    S M  W ++  V   
Sbjct: 381 GAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLV---SSDMKSWSTVLAVMGK 437

Query: 363 CLQSSFPWTLYLAMACIFAFIL-SFGIGPAGVTGILATELFDQMARPAACMVCGALMWIM 421
               +   T YL  + ++  +L   G+G   + G L   L      P A ++ G  +W+ 
Sbjct: 438 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSL-----APLAALLDG--VWLS 490

Query: 422 LILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPR 481
           L  +  G                 G+ +  A  T L LPET+     E  +++ R + P 
Sbjct: 491 LPKLTYG-----------------GIALLAA-GTALLLPETRQAQLPETIQDVERKSAPT 532

Query: 482 RAQ 484
             Q
Sbjct: 533 SLQ 535


>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
          Length = 727

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 22/161 (13%)

Query: 75  SLYPLGGLFGALLAGPLAITLGRKKSLL----VNNIFVVSAAILFGFSRKAGSFEMIMLG 130
           S+  LG + GA   G LA  +GRK+SLL    VN  F   ++ + G+          +  
Sbjct: 195 SIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYG-------FFLFC 247

Query: 131 RLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVV--------GLR 182
           RLL G   G ++     Y  E   +E RG       +F  +G +    +        G  
Sbjct: 248 RLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWS 307

Query: 183 ELLGGP---QAWPLLLASCLVPGALQLASLPLLPESPRYLL 220
             +G      +W + +  C +P    + +L  +PESPR+LL
Sbjct: 308 FSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLL 348


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,291,089
Number of Sequences: 37866
Number of extensions: 807405
Number of successful extensions: 2498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2391
Number of HSP's gapped (non-prelim): 73
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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