Guide to the Human Genome
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Search of human proteins with 6681762

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6681762 general transcription factor IIH, polypeptide 2,
44kD subunit [Homo sapiens]
         (395 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6681762 general transcription factor IIH, polypeptide 2, 44kD...   821   0.0  
gi|148922900 general transcription factor IIH, polypeptide 2B [H...   818   0.0  
gi|148922852 general transcription factor IIH, polypeptide 2C [H...   817   0.0  
gi|109809737 general transcription factor IIH, polypeptide 2D [H...   817   0.0  
gi|5292161 proteasome 26S non-ATPase subunit 4 [Homo sapiens]          42   0.001
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    34   0.26 
gi|7662424 zinc finger protein 510 [Homo sapiens]                      33   0.45 
gi|32698748 zinc finger protein 248 [Homo sapiens]                     33   0.59 
gi|7705495 zinc finger protein 581 [Homo sapiens]                      32   0.76 
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              32   1.00 
gi|194018469 zinc finger protein 546 [Homo sapiens]                    32   1.00 
gi|11968019 p53 target zinc finger protein isoform 1 [Homo sapiens]    32   1.3  
gi|23199978 p53 target zinc finger protein isoform 2 [Homo sapiens]    32   1.3  
gi|208431793 dynactin 4 (p62) isoform a [Homo sapiens]                 32   1.3  
gi|7705893 dynactin 4 (p62) isoform b [Homo sapiens]                   32   1.3  
gi|124301196 sodium channel, nonvoltage-gated 1, beta [Homo sapi...    31   1.7  
gi|190194429 zinc finger protein 267 [Homo sapiens]                    31   2.2  
gi|28274686 zinc finger protein 82 homolog [Homo sapiens]              30   2.9  
gi|29788755 SET binding factor 2 [Homo sapiens]                        30   2.9  
gi|24308227 zinc finger protein 687 [Homo sapiens]                     30   2.9  
gi|55741659 zinc finger protein 14-like [Homo sapiens]                 30   2.9  
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    30   3.8  
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...    30   3.8  
gi|158186614 transmembrane protein 118 isoform 1 [Homo sapiens]        30   5.0  
gi|5032281 dystrophin Dp427c isoform [Homo sapiens]                    29   6.5  
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]                   29   6.5  
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]                   29   6.5  
gi|208431815 protein tyrosine phosphatase, receptor type, K isof...    29   6.5  
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo...    29   6.5  
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                   29   6.5  

>gi|6681762 general transcription factor IIH, polypeptide 2, 44kD
           subunit [Homo sapiens]
          Length = 395

 Score =  821 bits (2120), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60
           MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH
Sbjct: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60

Query: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120
           LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL
Sbjct: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120

Query: 121 SGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180
           SGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPS
Sbjct: 121 SGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180

Query: 181 NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP 240
           NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP
Sbjct: 181 NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP 240

Query: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300
           ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE
Sbjct: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300

Query: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360
           LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC
Sbjct: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360

Query: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395
           AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV
Sbjct: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395


>gi|148922900 general transcription factor IIH, polypeptide 2B [Homo
           sapiens]
          Length = 395

 Score =  818 bits (2112), Expect = 0.0
 Identities = 393/395 (99%), Positives = 394/395 (99%)

Query: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60
           MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH
Sbjct: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60

Query: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120
           LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL
Sbjct: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120

Query: 121 SGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180
           SGNPRKHITSLKKAVDMTCHGEPSLYNSLS+AMQTLKHMPGHTSREVLIIFSSLTTCDPS
Sbjct: 121 SGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180

Query: 181 NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP 240
           NIYDLIKTLKAAKIRVSV GLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP
Sbjct: 181 NIYDLIKTLKAAKIRVSVTGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP 240

Query: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300
           ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE
Sbjct: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300

Query: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360
           LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC
Sbjct: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360

Query: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395
           AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV
Sbjct: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395


>gi|148922852 general transcription factor IIH, polypeptide 2C [Homo
           sapiens]
          Length = 395

 Score =  817 bits (2110), Expect = 0.0
 Identities = 392/395 (99%), Positives = 395/395 (100%)

Query: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60
           MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH
Sbjct: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60

Query: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120
           LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL
Sbjct: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120

Query: 121 SGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180
           SGNPRKHITSLK+AVDMTCHGEPSLYNSLS+AMQTLKHMPGHTSREVLIIFSSLTTCDPS
Sbjct: 121 SGNPRKHITSLKEAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180

Query: 181 NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP 240
           NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHH+SPPP
Sbjct: 181 NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHLSPPP 240

Query: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300
           ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE
Sbjct: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300

Query: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360
           LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC
Sbjct: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360

Query: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395
           AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV
Sbjct: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395


>gi|109809737 general transcription factor IIH, polypeptide 2D [Homo
           sapiens]
          Length = 395

 Score =  817 bits (2110), Expect = 0.0
 Identities = 392/395 (99%), Positives = 395/395 (100%)

Query: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60
           MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH
Sbjct: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRH 60

Query: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120
           LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL
Sbjct: 61  LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120

Query: 121 SGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180
           SGNPRKHITSLK+AVDMTCHGEPSLYNSLS+AMQTLKHMPGHTSREVLIIFSSLTTCDPS
Sbjct: 121 SGNPRKHITSLKEAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPS 180

Query: 181 NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHVSPPP 240
           NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHH+SPPP
Sbjct: 181 NIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDESHYKELLTHHLSPPP 240

Query: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300
           ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE
Sbjct: 241 ASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCE 300

Query: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360
           LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC
Sbjct: 301 LPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELKDQHVYVC 360

Query: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395
           AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV
Sbjct: 361 AVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPSGV 395


>gi|5292161 proteasome 26S non-ATPase subunit 4 [Homo sapiens]
          Length = 377

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 5/143 (3%)

Query: 63  VVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSG 122
           V VD S  M + D  P RL      +          NP + +G+I T +   E LT L+ 
Sbjct: 8   VCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLI-TLANDCEVLTTLTP 66

Query: 123 NPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKHMPGHTSREVLIIF-SSLTTCDPSN 181
           +  +    L K   +   G+ +    + +A   LKH  G   +  +I F  S    +  +
Sbjct: 67  DTGR---ILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKD 123

Query: 182 IYDLIKTLKAAKIRVSVIGLSAE 204
           +  L K LK  K+ V +I    E
Sbjct: 124 LVKLAKRLKKEKVNVDIINFGEE 146


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
           sapiens]
          Length = 4911

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 40/181 (22%), Positives = 59/181 (32%), Gaps = 23/181 (12%)

Query: 224 DESHYKELLTHHVSPPPASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPG 283
           D SH   L   H+   P  S  + +      P   +           +    LD    P 
Sbjct: 319 DFSHIFLLCPEHIDQAPERSKEDANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTP- 377

Query: 284 LTLGGYFCPQCRAKYCELPVECKICG--LTLVSAPHLARSYHHLFPLDAFQEIPLEEYNG 341
           L   G+ CP+C  K C+    CK  G    ++      + YH        + +P   +  
Sbjct: 378 LKRAGWQCPEC--KVCQ---NCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKC 432

Query: 342 E--RFCYGCQGELKDQHVYVCAVCQNVF------CVDCDVFVH-----DSLHC--CPGCI 386
           +  R C  C      Q  + C +C N +      C  C    H     D LHC  C   +
Sbjct: 433 KNCRICIECGTRSSSQWHHNCLICDNCYQQQDNLCPFCGKCYHPELQKDMLHCNMCKRWV 492

Query: 387 H 387
           H
Sbjct: 493 H 493


>gi|7662424 zinc finger protein 510 [Homo sapiens]
          Length = 683

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 37/179 (20%), Positives = 58/179 (32%), Gaps = 15/179 (8%)

Query: 156 LKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKAAK-IRVSVIGLSAEVRVCTVLARE 214
           +KH   HT             CD   ++D  +T    K + ++  G S E        + 
Sbjct: 270 VKHNSSHTGETSSKDDEFRKNCDKKTLFDHRRTGTGKKHLHLNQCGKSFEKSTVEEYNKL 329

Query: 215 TGGTYHVILDESHYKELLTHHVSPPPASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMA 274
             G  H  L+ S        H++ P  +   E  L+     Q  + S    + K S+  +
Sbjct: 330 NMGIKHYELNPSGNNFNRKAHLTDPQTAVIEENPLVSNDRTQTWVKSSEYHENKKSYQTS 389

Query: 275 HLDGNTEPGLTLGGYFCPQCRAKYC--------------ELPVECKICGLTLVSAPHLA 319
                      +  Y C +C   +C              E P EC  CG T     HL+
Sbjct: 390 VHRVRRRSHSMMKPYKCNECGKSFCQKGHLIQHQRTHTGEKPFECSECGKTFSQKSHLS 448


>gi|32698748 zinc finger protein 248 [Homo sapiens]
          Length = 579

 Score = 32.7 bits (73), Expect = 0.59
 Identities = 28/112 (25%), Positives = 38/112 (33%), Gaps = 25/112 (22%)

Query: 289 YFCPQCRAKYC--------------ELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEI 334
           Y C +C   +C              E P ECK CG T     +L              E 
Sbjct: 408 YECTECGKAFCQKPHLTNHQRTHTGEKPYECKQCGKTFCVKSNLTEHQR-----THTGEK 462

Query: 335 PLE-EYNGERFCYGC-----QGELKDQHVYVCAVCQNVFCVDCDVFVHDSLH 380
           P E    G+ FC+       Q     +  ++C  C   FCV  ++ VH   H
Sbjct: 463 PYECNACGKSFCHRSALTVHQRTHTGEKPFICNECGKSFCVKSNLIVHQRTH 514


>gi|7705495 zinc finger protein 581 [Homo sapiens]
          Length = 197

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 21/107 (19%)

Query: 237 SPPPASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGG-----YFC 291
           SP P  SSS  S      P+     L D    P   +   +   EPG +        Y C
Sbjct: 30  SPEPGPSSSIGSPQASSPPRPNHYLLIDTQGVPYTVLVDEESQREPGASGAPGQKKCYSC 89

Query: 292 PQCRAKYCEL--------------PVECKICGLTLVSAPHLARSYHH 324
           P C   +  +              P EC ICG     A HLAR  HH
Sbjct: 90  PVCSRVFEYMSYLQRHSITHSEVKPFECDICGKAFKRASHLAR--HH 134


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 32.0 bits (71), Expect = 1.00
 Identities = 24/80 (30%), Positives = 26/80 (32%)

Query: 289 YFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGC 348
           Y CPQCRA Y   P   K   L  V    L        P D +                C
Sbjct: 48  YLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVAC 107

Query: 349 QGELKDQHVYVCAVCQNVFC 368
              LK+  V  C VC   FC
Sbjct: 108 DHCLKEAAVKTCLVCMASFC 127


>gi|194018469 zinc finger protein 546 [Homo sapiens]
          Length = 836

 Score = 32.0 bits (71), Expect = 1.00
 Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 29/96 (30%)

Query: 300 ELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGER--FCYGC------QGE 351
           E+P ECK CG T  S  HL + Y                + GE+   C  C      QGE
Sbjct: 494 EIPYECKECGKTFSSRYHLTQHY--------------RIHTGEKPYICNECGKAFRLQGE 539

Query: 352 LKDQH-------VYVCAVCQNVFCVDCDVFVHDSLH 380
           L   H        Y C  C   F        H  +H
Sbjct: 540 LTRHHRIHTCEKPYECKECGKAFIHSNQFISHQRIH 575



 Score = 32.0 bits (71), Expect = 1.00
 Identities = 26/96 (27%), Positives = 35/96 (36%), Gaps = 29/96 (30%)

Query: 300 ELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGER--FCYGC------QGE 351
           ELP ECK CG T     HL + +                + GE+   C  C      Q E
Sbjct: 718 ELPYECKECGKTFSRRYHLTQHF--------------RLHTGEKPYSCKECGNAFRLQAE 763

Query: 352 LKDQHV-------YVCAVCQNVFCVDCDVFVHDSLH 380
           L   H+       Y C  C   F V+ ++  H  +H
Sbjct: 764 LTRHHIVHTGEKPYKCKECGKAFSVNSELTRHHRIH 799


>gi|11968019 p53 target zinc finger protein isoform 1 [Homo sapiens]
          Length = 289

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 5/92 (5%)

Query: 231 LLTHHVSPPPASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYF 290
           LL H V PPP   S       M     +  +L     KP    A L    E  L+ GG  
Sbjct: 3   LLQHAVLPPPKQPSPSPP---MSVATRSTGTLQLPPQKPFGQEASLPLAGEEELSKGGE- 58

Query: 291 CPQCRAKYCELPVECKICGLTLVSAPHLARSY 322
              C  +    P+ CK+C +TL SA      Y
Sbjct: 59  -QDCALEELCKPLYCKLCNVTLNSAQQAQAHY 89


>gi|23199978 p53 target zinc finger protein isoform 2 [Homo sapiens]
          Length = 288

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 5/92 (5%)

Query: 231 LLTHHVSPPPASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYF 290
           LL H V PPP   S       M     +  +L     KP    A L    E  L+ GG  
Sbjct: 3   LLQHAVLPPPKQPSPSPP---MSVATRSTGTLQLPPQKPFGQEASLPLAGEEELSKGGE- 58

Query: 291 CPQCRAKYCELPVECKICGLTLVSAPHLARSY 322
              C  +    P+ CK+C +TL SA      Y
Sbjct: 59  -QDCALEELCKPLYCKLCNVTLNSAQQAQAHY 89


>gi|208431793 dynactin 4 (p62) isoform a [Homo sapiens]
          Length = 467

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 5/54 (9%)

Query: 342 ERFCYGCQGELKDQ----HVYVCAVCQNVFCVDCDVFVHDSLHCCPGCIHKIPA 391
           +R  Y  QGE K +     +Y C  C  +  ++C     DS H CP C+  +P+
Sbjct: 8   DRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDS-HYCPSCLENMPS 60


>gi|7705893 dynactin 4 (p62) isoform b [Homo sapiens]
          Length = 460

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 5/54 (9%)

Query: 342 ERFCYGCQGELKDQ----HVYVCAVCQNVFCVDCDVFVHDSLHCCPGCIHKIPA 391
           +R  Y  QGE K +     +Y C  C  +  ++C     DS H CP C+  +P+
Sbjct: 8   DRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDS-HYCPSCLENMPS 60


>gi|124301196 sodium channel, nonvoltage-gated 1, beta [Homo
           sapiens]
          Length = 640

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 31/157 (19%), Positives = 55/157 (35%), Gaps = 15/157 (9%)

Query: 205 VRVCTVLARETGGTYHVILDESHYKELLTHHVSPPPASSSSECSLIRMGFPQHTIASLSD 264
           V +C     +     H++ D     E +   +  P  S ++    +      HT   L D
Sbjct: 95  VTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLID 154

Query: 265 QDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCELPVECKICGL--------TLVSAP 316
           +       +  L G+   GLT        C A  C++ +  ++C L           SA 
Sbjct: 155 ERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAM--RLCSLNRTQCTFRNFTSAT 212

Query: 317 HLARSYHHLFPLDAFQEIPLEE-----YNGERFCYGC 348
                ++ L   + F ++P +E     Y GE+    C
Sbjct: 213 QALTEWYILQATNIFAQVPQQELVEMSYPGEQMILAC 249


>gi|190194429 zinc finger protein 267 [Homo sapiens]
          Length = 743

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 13/89 (14%)

Query: 300 ELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLE-EYNGERFCYGCQGELKDQ--- 355
           E P +C+ CG +L  + HL +  H + P +   E P + +  G+ F   C   L  Q   
Sbjct: 319 EKPYKCEKCGDSLNHSLHLTQ--HQIIPTE---EKPYKWKECGKVFNLNCSLYLTKQQQI 373

Query: 356 ----HVYVCAVCQNVFCVDCDVFVHDSLH 380
               ++Y C  C   F    ++ VH  +H
Sbjct: 374 DTGENLYKCKACSKSFTRSSNLIVHQRIH 402



 Score = 29.3 bits (64), Expect = 6.5
 Identities = 24/96 (25%), Positives = 30/96 (31%), Gaps = 29/96 (30%)

Query: 300 ELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGER--FCYGCQGELKD--- 354
           E P +CK CG     + HL R  HH              + GE+   C  C     D   
Sbjct: 545 EKPYKCKECGKAFPYSSHLIR--HHRI------------HTGEKPYKCKACSKSFSDSSG 590

Query: 355 ----------QHVYVCAVCQNVFCVDCDVFVHDSLH 380
                     +  Y C  C   F    DV  H  +H
Sbjct: 591 LTVHRRTHTGEKPYTCKECGKAFSYSSDVIQHRRIH 626


>gi|28274686 zinc finger protein 82 homolog [Homo sapiens]
          Length = 532

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 9/86 (10%)

Query: 300 ELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGEL-KDQHV- 357
           E P ECK CG+      HL R       L + +++   +  GE F  G    + +  H+ 
Sbjct: 195 EKPYECKECGMAFRQTAHLTRHQR----LHSGEKLYECKECGEAFICGADLRVHQKMHIG 250

Query: 358 ---YVCAVCQNVFCVDCDVFVHDSLH 380
              Y C  C   F V   + +H  +H
Sbjct: 251 EKPYECKECGKAFRVRGQLTLHQRIH 276


>gi|29788755 SET binding factor 2 [Homo sapiens]
          Length = 1849

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 71   MEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSG--NPRKHI 128
            +E + LKPN    +LK  +Y++EE     P S   +++T      + ++L+G   PR   
Sbjct: 1563 LEIEALKPNVNVSSLKKWDYYIEETLSTGP-SYDWMMLTPKHFPSEDSDLAGEAGPRSQR 1621

Query: 129  TSLKKAVDMTCHGEPSLYNSLSIAMQTLKH 158
             ++    D     +P    SL   ++ L+H
Sbjct: 1622 RTVWPCYDDVSCTQPDALTSLFSEIEKLEH 1651


>gi|24308227 zinc finger protein 687 [Homo sapiens]
          Length = 1237

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 26/120 (21%), Positives = 37/120 (30%), Gaps = 34/120 (28%)

Query: 288 GYFCPQC--------------RAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQE 333
           GY CP C              +  +CE+  +C IC +   S P      +   P    Q+
Sbjct: 763 GYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQ 822

Query: 334 IPLEEYNGERFCYGCQGELKDQHVYVCAVCQNVFCVDCDVFVHDSLHCCPGCIHKIPAPS 393
             L                    +Y CA+C  VF     +  H   H  P  +     PS
Sbjct: 823 AKL--------------------IYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPS 862


>gi|55741659 zinc finger protein 14-like [Homo sapiens]
          Length = 533

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 13/88 (14%)

Query: 300 ELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEYNGERFCYGCQGELK------ 353
           E P ECK CG T     HL R +  L   +   E    +  G+ F   C  +L+      
Sbjct: 281 EKPYECKDCGKTFRQCTHLTR-HQRLHTAEKLYEC---KECGKAFV--CGPDLRVHQKIH 334

Query: 354 -DQHVYVCAVCQNVFCVDCDVFVHDSLH 380
             +  Y C  C   F +   + VH S+H
Sbjct: 335 FGEKPYECKECGKAFRICQQLTVHQSIH 362


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 28/128 (21%), Positives = 44/128 (34%), Gaps = 30/128 (23%)

Query: 287 GGYFCPQCRAKYCELP-------VECKICGLTLVSAP-----HLARSYHHLFPLDAFQEI 334
           G  FC  C  +YCE+P         C +C              LA    ++  L     +
Sbjct: 32  GHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTL 91

Query: 335 PLEE-----YNGERFCYGCQGELKDQHVYVCAVCQNV---------FCVDCDVFVHDSLH 380
            L E      +GE+  + C+    D  + +C VC+           F  D      + +H
Sbjct: 92  GLGEEDVCQEHGEKIYFFCE----DDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIH 147

Query: 381 CCPGCIHK 388
            C  C+ K
Sbjct: 148 KCLKCLRK 155


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 28/128 (21%), Positives = 44/128 (34%), Gaps = 30/128 (23%)

Query: 287 GGYFCPQCRAKYCELP-------VECKICGLTLVSAP-----HLARSYHHLFPLDAFQEI 334
           G  FC  C  +YCE+P         C +C              LA    ++  L     +
Sbjct: 32  GHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTL 91

Query: 335 PLEE-----YNGERFCYGCQGELKDQHVYVCAVCQNV---------FCVDCDVFVHDSLH 380
            L E      +GE+  + C+    D  + +C VC+           F  D      + +H
Sbjct: 92  GLGEEDVCQEHGEKIYFFCE----DDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIH 147

Query: 381 CCPGCIHK 388
            C  C+ K
Sbjct: 148 KCLKCLRK 155


>gi|158186614 transmembrane protein 118 isoform 1 [Homo sapiens]
          Length = 444

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 345 CYGCQGELKDQHVYVCAVCQNVFCVDCDVFVHDSLHCCPGC 385
           C  CQ E ++  + +C   Q+VFC +C     D    CP C
Sbjct: 384 CAICQAEFREPLILLC---QHVFCEECLCLWLDRERTCPLC 421


>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
          Length = 3677

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 3/71 (4%)

Query: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEH---HGQVRLGM 57
           MD + ++ K       +T E  ++ E   L   +ED+  + ++ +V +      QVR+  
Sbjct: 442 MDLQNQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNS 501

Query: 58  MRHLYVVVDGS 68
           + H+ VVVD S
Sbjct: 502 LTHMVVVVDES 512


>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
          Length = 3562

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 3/71 (4%)

Query: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEH---HGQVRLGM 57
           MD + ++ K       +T E  ++ E   L   +ED+  + ++ +V +      QVR+  
Sbjct: 327 MDLQNQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNS 386

Query: 58  MRHLYVVVDGS 68
           + H+ VVVD S
Sbjct: 387 LTHMVVVVDES 397


>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
          Length = 3681

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 3/71 (4%)

Query: 1   MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEH---HGQVRLGM 57
           MD + ++ K       +T E  ++ E   L   +ED+  + ++ +V +      QVR+  
Sbjct: 446 MDLQNQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNS 505

Query: 58  MRHLYVVVDGS 68
           + H+ VVVD S
Sbjct: 506 LTHMVVVVDES 516


>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform
           a [Homo sapiens]
          Length = 1446

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 14/41 (34%), Positives = 25/41 (60%)

Query: 106 IIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLY 146
           +IV KSK A+K  +  GN R+ +T +  A+D +   + +L+
Sbjct: 773 LIVKKSKLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLH 813


>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform
           b [Homo sapiens]
          Length = 1440

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 14/41 (34%), Positives = 25/41 (60%)

Query: 106 IIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLY 146
           +IV KSK A+K  +  GN R+ +T +  A+D +   + +L+
Sbjct: 773 LIVKKSKLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLH 813


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 36/169 (21%), Positives = 68/169 (40%), Gaps = 10/169 (5%)

Query: 61   LYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTEL 120
            L   +D SR + +Q+ +  +      + +  V E  +  P+     I++ +  A  L   
Sbjct: 1758 LVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRE--NSCPVGAHIAILSYNSHARHLVRF 1815

Query: 121  SGNPRKHITSLKKAVDMTCHGEPSLYNSLSIAMQTLKH------MPGHTSREVLIIFSSL 174
            S   +K  + L + ++   +   S    +  AM+ +        +PG  +R++   FSS 
Sbjct: 1816 SDAYKK--SQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSG 1873

Query: 175  TTCDPSNIYDLIKTLKAAKIRVSVIGLSAEVRVCTVLARETGGTYHVIL 223
             + D  +I        A +I   VI  S    V    A +  GT+ VI+
Sbjct: 1874 QSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIV 1922


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,783,461
Number of Sequences: 37866
Number of extensions: 779999
Number of successful extensions: 3680
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 3619
Number of HSP's gapped (non-prelim): 91
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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