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Search of human proteins with 66346728
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66346728 laforin isoform b [Homo sapiens]
(317 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66346728 laforin isoform b [Homo sapiens] 674 0.0
gi|11321613 laforin isoform a [Homo sapiens] 659 0.0
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 42 5e-04
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 42 7e-04
gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isofo... 41 0.002
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 40 0.004
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 37 0.023
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 37 0.030
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 36 0.039
gi|6005956 dual specificity phosphatase 12 [Homo sapiens] 36 0.051
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 36 0.051
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 36 0.051
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 36 0.051
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 35 0.067
gi|239743797 PREDICTED: similar to cell recognition molecule CAS... 35 0.067
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 35 0.067
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 35 0.067
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 35 0.067
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 34 0.15
gi|239582767 slingshot homolog 3 [Homo sapiens] 34 0.20
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 34 0.20
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 34 0.20
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 33 0.33
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 33 0.33
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 33 0.43
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 33 0.43
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 33 0.43
gi|214832050 dual specificity phosphatase 19 isoform 2 [Homo sap... 32 0.57
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 32 0.74
gi|37674210 slingshot 2 [Homo sapiens] 32 0.74
>gi|66346728 laforin isoform b [Homo sapiens]
Length = 317
Score = 674 bits (1740), Expect = 0.0
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLW 60
MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLW
Sbjct: 1 MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLW 60
Query: 61 LGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDG 120
LGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDG
Sbjct: 61 LGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDG 120
Query: 121 VYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKL 180
VYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKL
Sbjct: 121 VYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKL 180
Query: 181 KHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEG 240
KHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEG
Sbjct: 181 KHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEG 240
Query: 241 RVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
RVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR
Sbjct: 241 RVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
Query: 301 PAVYIDEEAASQDTFPL 317
PAVYIDEEAASQDTFPL
Sbjct: 301 PAVYIDEEAASQDTFPL 317
>gi|11321613 laforin isoform a [Homo sapiens]
Length = 331
Score = 659 bits (1701), Expect = 0.0
Identities = 312/318 (98%), Positives = 313/318 (98%), Gaps = 3/318 (0%)
Query: 1 MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLW 60
MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLW
Sbjct: 1 MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLW 60
Query: 61 LGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDG 120
LGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDG
Sbjct: 61 LGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDG 120
Query: 121 VYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKL 180
VYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKL
Sbjct: 121 VYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKL 180
Query: 181 KHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEG 240
KHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEG
Sbjct: 181 KHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEG 240
Query: 241 RVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
RVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR
Sbjct: 241 RVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
Query: 301 PAVYIDEEA---ASQDTF 315
PAVYIDEEA A +D F
Sbjct: 301 PAVYIDEEALARAQEDFF 318
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 42.4 bits (98), Expect = 5e-04
Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 26/147 (17%)
Query: 158 SRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEP-MTPDT 216
+RILPN++LG C R V + +L + GI V+N N P+P P++
Sbjct: 160 TRILPNLYLG-CQRDV--LNKELMQQNGIGYVLN------------ASNTCPKPDFIPES 204
Query: 217 MIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAA 276
++ +P D E + L ++V + V VHC AG+ RS
Sbjct: 205 H----------FLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATI 254
Query: 277 VCGWLQYVMGWNLRKVQYFLMAKRPAV 303
++ M +L + F+ KRP +
Sbjct: 255 AIAYIMKRMDMSLDEAYRFVKEKRPTI 281
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 42.0 bits (97), Expect = 7e-04
Identities = 22/78 (28%), Positives = 35/78 (44%)
Query: 226 LAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVM 285
L Y W+P D T +A+ + + EKG V VHC AG+ RS +L
Sbjct: 223 LHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTK 282
Query: 286 GWNLRKVQYFLMAKRPAV 303
+ L++ ++ +R V
Sbjct: 283 QFRLKEAFDYIKQRRSMV 300
>gi|148224884 protein tyrosine phosphatase, mitochondrial 1 isoform
1 [Homo sapiens]
Length = 201
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 15/132 (11%)
Query: 157 YSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDT 216
Y RI P + LG+ P + +T +L + + V+ E++ CN E
Sbjct: 38 YHRIDPTVLLGALP--LRSLTRQLVQDENVRGVITMNEEYE---TRFLCNSSQE------ 86
Query: 217 MIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAA 276
++ G+ + + T DM+ + L + V G VYVHC AG RS
Sbjct: 87 ----WKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQCVYVHCKAGRSRSATM 142
Query: 277 VCGWLQYVMGWN 288
V +L V W+
Sbjct: 143 VAAYLIQVHKWS 154
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 39.7 bits (91), Expect = 0.004
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 224 EGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQY 283
EG+ Y+ +P D ++ + +++ +H +G VHC AGV RS V ++
Sbjct: 46 EGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMT 105
Query: 284 V--MGW 287
V GW
Sbjct: 106 VTDFGW 111
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 37.0 bits (84), Expect = 0.023
Identities = 21/78 (26%), Positives = 33/78 (42%)
Query: 224 EGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQY 283
+ + Y+ +P D + + + +H G VHC AG+ RST V ++
Sbjct: 46 QDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMT 105
Query: 284 VMGWNLRKVQYFLMAKRP 301
V G R V + A RP
Sbjct: 106 VTGLGWRDVLEAIKATRP 123
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 36.6 bits (83), Expect = 0.030
Identities = 33/150 (22%), Positives = 59/150 (39%), Gaps = 23/150 (15%)
Query: 151 GHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPE 210
G +A +ILPN++LGS + ++ +LGI ++N
Sbjct: 198 GLRASFPVQILPNLYLGSAR---DSANLESLAKLGIRYILN------------------- 235
Query: 211 PMTPDTMIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGV 270
+TP+ + Y +P D ++ + P+A+ + L + V VHC AGV
Sbjct: 236 -VTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGV 294
Query: 271 GRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
RS +L + +L + K+
Sbjct: 295 SRSVTVTVAYLMQKLHLSLNDAYDLVKRKK 324
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 36.2 bits (82), Expect = 0.039
Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 23/142 (16%)
Query: 159 RILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMI 218
+ILP ++LG C + ++ + K+ GI ++N +TP+
Sbjct: 247 QILPYLYLG-CAKDSTNLDVLGKY--GIKYILN--------------------VTPNLPN 283
Query: 219 KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVC 278
Y +P D ++ Q P+A+ + K V VHC AG+ RS
Sbjct: 284 AFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTV 343
Query: 279 GWLQYVMGWNLRKVQYFLMAKR 300
+L M +L F+ K+
Sbjct: 344 AYLMQKMNLSLNDAYDFVKRKK 365
>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
Length = 340
Score = 35.8 bits (81), Expect = 0.051
Identities = 33/148 (22%), Positives = 54/148 (36%), Gaps = 21/148 (14%)
Query: 160 ILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIK 219
+ P ++ G E ++ E GITAV+ +E + G
Sbjct: 30 VQPGLYFGGAAAVAEPDHLR---EAGITAVLTVDSEEPSFKAGPGV-------------- 72
Query: 220 LYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCG 279
E L +++P D + L + V + +G V VHC+AGV RS A +
Sbjct: 73 ----EDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITA 128
Query: 280 WLQYVMGWNLRKVQYFLMAKRPAVYIDE 307
+L K L +P ++E
Sbjct: 129 FLMKTDQLPFEKAYEKLQILKPEAKMNE 156
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 35.8 bits (81), Expect = 0.051
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 216 TMIKLYR-EEGLA-YIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRS 273
T + LY E+GL Y +P D + + Q +A + + G + +HC AGV RS
Sbjct: 14 THLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRS 73
Query: 274 TAAVCGWLQYVMGWNLRKVQYFLMAKRPAV 303
V +L + F+ KRP +
Sbjct: 74 ATIVIAYLMKHTRMTMTDAYKFVKGKRPII 103
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 35.8 bits (81), Expect = 0.051
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 216 TMIKLYR-EEGLA-YIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRS 273
T + LY E+GL Y +P D + + Q +A + + G + +HC AGV RS
Sbjct: 14 THLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRS 73
Query: 274 TAAVCGWLQYVMGWNLRKVQYFLMAKRPAV 303
V +L + F+ KRP +
Sbjct: 74 ATIVIAYLMKHTRMTMTDAYKFVKGKRPII 103
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 35.8 bits (81), Expect = 0.051
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
Query: 216 TMIKLYR-EEGLA-YIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRS 273
T + LY E+GL Y +P D + + Q +A + + G + +HC AGV RS
Sbjct: 356 THLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRS 415
Query: 274 TAAVCGWLQYVMGWNLRKVQYFLMAKRPAV 303
V +L + F+ KRP +
Sbjct: 416 ATIVIAYLMKHTRMTMTDAYKFVKGKRPII 445
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 35.4 bits (80), Expect = 0.067
Identities = 19/73 (26%), Positives = 31/73 (42%)
Query: 228 YIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGW 287
Y+ + D E ++ P + L+ G V VH NAG+ RS A V ++ G
Sbjct: 82 YLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGM 141
Query: 288 NLRKVQYFLMAKR 300
R ++ +R
Sbjct: 142 KYRDAFAYVQERR 154
>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
[Homo sapiens]
Length = 944
Score = 35.4 bits (80), Expect = 0.067
Identities = 36/119 (30%), Positives = 44/119 (36%), Gaps = 28/119 (23%)
Query: 24 GSRPELGRWEPRGAVRLRPA---GTAAGDGALALQEPGLWLGEVELAAEEAAQDGAEPG- 79
G P +W P LR G AAG G EPG G + AA A +D A PG
Sbjct: 358 GDPPRCPQWAPALGCVLRVRSGRGAAAGRG-----EPG---GALRAAAGSALRDSAAPGL 409
Query: 80 ---RVDTFWYKFLKREPGG-------------ELSWEGNGPHHDRCCTYNENNLVDGVY 122
V + +K RE G SW G+ P +C E N +D Y
Sbjct: 410 TSLMVKSVTFKVAFREEYGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQY 468
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 35.4 bits (80), Expect = 0.067
Identities = 19/73 (26%), Positives = 31/73 (42%)
Query: 228 YIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGW 287
Y+ + D E ++ P + L+ G V VH NAG+ RS A V ++ G
Sbjct: 82 YLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGM 141
Query: 288 NLRKVQYFLMAKR 300
R ++ +R
Sbjct: 142 KYRDAFAYVQERR 154
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 35.4 bits (80), Expect = 0.067
Identities = 19/73 (26%), Positives = 31/73 (42%)
Query: 228 YIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGW 287
Y+ + D E ++ P + L+ G V VH NAG+ RS A V ++ G
Sbjct: 82 YLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGM 141
Query: 288 NLRKVQYFLMAKR 300
R ++ +R
Sbjct: 142 KYRDAFAYVQERR 154
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 35.4 bits (80), Expect = 0.067
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 158 SRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTM 217
+RILP+++LGS Q + + L + GI+ V+N S+ C + PD +
Sbjct: 162 TRILPHLYLGS---QKDVLNKDLMTQNGISYVLNA---------SNSCPK------PDFI 203
Query: 218 IKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAV 277
+ ++ +P D E + L +++ + V VHC AG+ RS
Sbjct: 204 CES------RFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIA 257
Query: 278 CGWLQYVMGWNLRKVQYFLMAKRPAV 303
++ MG + F+ +RP++
Sbjct: 258 IAYIMKTMGMSSDDAYRFVKDRRPSI 283
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 34.3 bits (77), Expect = 0.15
Identities = 36/126 (28%), Positives = 53/126 (42%), Gaps = 28/126 (22%)
Query: 160 ILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIK 219
ILP ++LGSC + ++ GITAV+N S+ C P+
Sbjct: 176 ILPYLFLGSCSHSSD---LQGLQACGITAVLNV---------SASC--------PNHFEG 215
Query: 220 LYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCG 279
L+R Y +P D +A+ + + G V VHC AG+ RS A +C
Sbjct: 216 LFR-----YKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRS-ATIC- 268
Query: 280 WLQYVM 285
L Y+M
Sbjct: 269 -LAYLM 273
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 33.9 bits (76), Expect = 0.20
Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 29/146 (19%)
Query: 158 SRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTM 217
SRI P+++LGS + ++ +T ++N E D N YPE T
Sbjct: 330 SRIFPHLYLGS---EWNAANLEELQRNRVTHILNMAREID--------NFYPERFTYHN- 377
Query: 218 IKLYREEGLAYI--WMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTA 275
++L+ EE + W T R Q G V VHC GV RS A
Sbjct: 378 VRLWDEESAQLLPHWKETHRFIEAARAQ---------------GTHVLVHCKMGVSRSAA 422
Query: 276 AVCGWLQYVMGWNLRKVQYFLMAKRP 301
V + +L + + RP
Sbjct: 423 TVLAYAMKQYECSLEQALRHVQELRP 448
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 33.9 bits (76), Expect = 0.20
Identities = 19/80 (23%), Positives = 32/80 (40%)
Query: 224 EGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQY 283
EG+ YI +P D L+H + + +HC AGV RS + +L
Sbjct: 64 EGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMK 123
Query: 284 VMGWNLRKVQYFLMAKRPAV 303
+L + ++RP +
Sbjct: 124 YHSMSLLDAHTWTKSRRPII 143
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 33.9 bits (76), Expect = 0.20
Identities = 16/47 (34%), Positives = 23/47 (48%)
Query: 235 DMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWL 281
D+ + P+ + K +V VHCNAGV R+ A V G+L
Sbjct: 119 DLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFL 165
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 33.1 bits (74), Expect = 0.33
Identities = 31/142 (21%), Positives = 56/142 (39%), Gaps = 25/142 (17%)
Query: 160 ILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIK 219
ILP ++LG C + + + + E GI ++N +TP+ +
Sbjct: 210 ILPFLYLG-CAK--DSTNLDVLEEFGIKYILN--------------------VTPN-LPN 245
Query: 220 LYREEG-LAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVC 278
L+ G Y +P D ++ Q P+A+ + K V VHC AG+ RS
Sbjct: 246 LFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTV 305
Query: 279 GWLQYVMGWNLRKVQYFLMAKR 300
+L + ++ + K+
Sbjct: 306 AYLMQKLNLSMNDAYDIVKMKK 327
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 33.1 bits (74), Expect = 0.33
Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 30/134 (22%)
Query: 160 ILPNIWLGSCPRQVEHVTIK-LKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMI 218
ILP ++LGS H + K + LGITA++N S+ C +
Sbjct: 177 ILPFLYLGSA----YHASRKDMLDALGITALINV---------SANCPNH---------- 213
Query: 219 KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVC 278
E Y +P D +A+ + ++ G V+VHC AG+ RS A +C
Sbjct: 214 ---FEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRS-ATIC 269
Query: 279 GWLQYVMGWNLRKV 292
L Y+M N K+
Sbjct: 270 --LAYLMRTNRVKL 281
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 32.7 bits (73), Expect = 0.43
Identities = 14/37 (37%), Positives = 18/37 (48%)
Query: 264 VHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
VHC GV RS + V + GW L K ++ KR
Sbjct: 391 VHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKR 427
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 32.7 bits (73), Expect = 0.43
Identities = 14/37 (37%), Positives = 18/37 (48%)
Query: 264 VHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
VHC GV RS + V + GW L K ++ KR
Sbjct: 402 VHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKR 438
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 32.7 bits (73), Expect = 0.43
Identities = 14/37 (37%), Positives = 18/37 (48%)
Query: 264 VHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
VHC GV RS + V + GW L K ++ KR
Sbjct: 391 VHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKR 427
>gi|214832050 dual specificity phosphatase 19 isoform 2 [Homo
sapiens]
Length = 166
Score = 32.3 bits (72), Expect = 0.57
Identities = 14/24 (58%), Positives = 17/24 (70%)
Query: 258 KGHIVYVHCNAGVGRSTAAVCGWL 281
K +V VHCNAGV R+ A V G+L
Sbjct: 91 KDGVVLVHCNAGVSRAAAIVIGFL 114
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 32.0 bits (71), Expect = 0.74
Identities = 21/80 (26%), Positives = 32/80 (40%)
Query: 222 REEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWL 281
R G+A + +P D E + L + A + G V+C G RS A +L
Sbjct: 59 RAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYL 118
Query: 282 QYVMGWNLRKVQYFLMAKRP 301
G +L K + + RP
Sbjct: 119 MRHRGLSLAKAFQMVKSARP 138
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 32.0 bits (71), Expect = 0.74
Identities = 13/37 (35%), Positives = 19/37 (51%)
Query: 264 VHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR 300
VHC GV RS + V + GWNL + ++ +R
Sbjct: 390 VHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERR 426
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.453
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,023,680
Number of Sequences: 37866
Number of extensions: 686691
Number of successful extensions: 1548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1513
Number of HSP's gapped (non-prelim): 60
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.