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Search of human proteins with 65301130
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|65301130 kazrin isoform B [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|65301130 kazrin isoform B [Homo sapiens] 826 0.0
gi|63147424 kazrin isoform A [Homo sapiens] 688 0.0
gi|157837985 kazrin isoform E [Homo sapiens] 656 0.0
gi|65301128 kazrin isoform C [Homo sapiens] 645 0.0
gi|63999741 kazrin isoform C [Homo sapiens] 645 0.0
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 62 7e-10
gi|203096856 kinesin family member 7 [Homo sapiens] 61 2e-09
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 60 3e-09
gi|45439327 periplakin [Homo sapiens] 59 6e-09
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 58 1e-08
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 57 2e-08
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 57 2e-08
gi|38044112 restin isoform b [Homo sapiens] 57 2e-08
gi|4506751 restin isoform a [Homo sapiens] 57 2e-08
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 57 3e-08
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 57 3e-08
gi|222537714 taxilin beta [Homo sapiens] 56 5e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 56 7e-08
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 56 7e-08
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 54 2e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 54 3e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 54 3e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 54 3e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 54 3e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 54 3e-07
gi|42794779 myosin 18A isoform b [Homo sapiens] 54 3e-07
gi|28416946 myosin 18A isoform a [Homo sapiens] 54 3e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 53 4e-07
gi|34577114 cytomatrix protein p110 [Homo sapiens] 53 4e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 53 4e-07
>gi|65301130 kazrin isoform B [Homo sapiens]
Length = 415
Score = 826 bits (2133), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MRAADSGSWERVRQLAAQGEPAPSCGAGAGPARPPGPAACEQCVDAAGPGDRPRAGVPRV 60
MRAADSGSWERVRQLAAQGEPAPSCGAGAGPARPPGPAACEQCVDAAGPGDRPRAGVPRV
Sbjct: 1 MRAADSGSWERVRQLAAQGEPAPSCGAGAGPARPPGPAACEQCVDAAGPGDRPRAGVPRV 60
Query: 61 RADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQ 120
RADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQ
Sbjct: 61 RADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQ 120
Query: 121 KEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE 180
KEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE
Sbjct: 121 KEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE 180
Query: 181 SEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQS 240
SEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQS
Sbjct: 181 SEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQS 240
Query: 241 LATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQA 300
LATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQA
Sbjct: 241 LATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQA 300
Query: 301 VRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQ 360
VRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQ
Sbjct: 301 VRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQ 360
Query: 361 SLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW 415
SLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 361 SLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW 415
>gi|63147424 kazrin isoform A [Homo sapiens]
Length = 421
Score = 688 bits (1775), Expect = 0.0
Identities = 360/402 (89%), Positives = 363/402 (90%), Gaps = 9/402 (2%)
Query: 14 QLAAQGEPAPSCGAGAGPARPPGPAACEQCVDAAGPGDRPRAGVPRVRADGDCSQPVLLR 73
+L A G GP PG AA AAG P++ A VLLR
Sbjct: 29 ELTATNRRLAELSGGGGPGPGPGAAAS---ASAAGDSAATNMENPQLGAQ------VLLR 79
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 133
EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ
Sbjct: 80 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 139
Query: 134 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD
Sbjct: 140 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD 199
Query: 194 LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 253
LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS
Sbjct: 200 LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 259
Query: 254 LAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSV 313
LAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSV
Sbjct: 260 LAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSV 319
Query: 314 ISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKK 373
ISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKK
Sbjct: 320 ISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKK 379
Query: 374 KEKMGFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW 415
KEKMGFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 380 KEKMGFGSISRVFARGKQRKSLDPGLFDGTAPDYYIEEDADW 421
>gi|157837985 kazrin isoform E [Homo sapiens]
Length = 775
Score = 656 bits (1692), Expect = 0.0
Identities = 346/388 (89%), Positives = 349/388 (89%), Gaps = 9/388 (2%)
Query: 14 QLAAQGEPAPSCGAGAGPARPPGPAACEQCVDAAGPGDRPRAGVPRVRADGDCSQPVLLR 73
+L A G GP PG AA AAG P++ A VLLR
Sbjct: 29 ELTATNRRLAELSGGGGPGPGPGAAAS---ASAAGDSAATNMENPQLGAQ------VLLR 79
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 133
EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ
Sbjct: 80 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 139
Query: 134 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD
Sbjct: 140 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD 199
Query: 194 LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 253
LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS
Sbjct: 200 LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 259
Query: 254 LAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSV 313
LAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSV
Sbjct: 260 LAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSV 319
Query: 314 ISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKK 373
ISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKK
Sbjct: 320 ISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKK 379
Query: 374 KEKMGFGSISRVFARGKQRKSLDPGLFD 401
KEKMGFGSISRVFARGKQRKSLDPGLFD
Sbjct: 380 KEKMGFGSISRVFARGKQRKSLDPGLFD 407
>gi|65301128 kazrin isoform C [Homo sapiens]
Length = 327
Score = 645 bits (1665), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 89 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 148
MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
Query: 149 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 208
LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
Query: 209 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 268
ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
Query: 269 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 328
VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
Query: 329 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 388
SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
Query: 389 GKQRKSLDPGLFDGTAPDYYIEEDADW 415
GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
>gi|63999741 kazrin isoform C [Homo sapiens]
Length = 327
Score = 645 bits (1665), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 89 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 148
MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
Query: 149 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 208
LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
Query: 209 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 268
ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
Query: 269 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 328
VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
Query: 329 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 388
SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
Query: 389 GKQRKSLDPGLFDGTAPDYYIEEDADW 415
GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 62.4 bits (150), Expect = 7e-10
Identities = 54/190 (28%), Positives = 92/190 (48%), Gaps = 25/190 (13%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA 131
L EE R+QE LL Q K+ LAK + + + + E L + RVQ + E+ LAR KE
Sbjct: 705 LEEERKRMQELESLLAQQKKALAKSITQEKN-RVKEALEEEQTRVQ--ELEERLARQKEV 761
Query: 132 LQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVK-ALAK 190
L++ A KR E LES + +++D + Q ++ SE + K
Sbjct: 762 LESSIAHEKRKAKE-------------ALESEKRKVQDLENHLTQQKEISESNIAYEKRK 808
Query: 191 EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNR----MKELEAELAMAKQSLATLTK 246
K+ +E+EK ++ ++ + T + +L+LK+ + +L LAM +++ T
Sbjct: 809 AKEAMEKEK----KKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKAT 864
Query: 247 DVPKRHSLAM 256
+ K SLA+
Sbjct: 865 ESLKAESLAL 874
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/180 (24%), Positives = 91/180 (50%), Gaps = 20/180 (11%)
Query: 70 VLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
+LL +EVSRL + + + K+++ +L+ S +V T R Q E+E+++
Sbjct: 231 LLLGKEVSRLSD-YEIESKYKDVIIANLQNEVAELSQKVSETTTSR----QNEKEISQKC 285
Query: 130 EAL-QAMKADRKRLKGEKTDLVSQMQQLYA-----TLESREEQLRDFIRNYEQHRKESED 183
+ L + + A +K ++ K+ +S +Q+ Y+ TL R ++ ++N ++ K
Sbjct: 286 QVLDEDIDAKQKEIQSLKSQ-ISALQKGYSKVLCQTLSERNSEITS-LKNEGENLKRDNA 343
Query: 184 AVKALAK--EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
+ +KD+L ++ E +Q KE H L+SQ KD++++ L + ++ K+ L
Sbjct: 344 ITSGMVSSLQKDILAKD--EQVQQLKEEVSH---LKSQNKDKDHQLEALGSRCSVLKEEL 398
Score = 39.7 bits (91), Expect = 0.005
Identities = 31/118 (26%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 123 QELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESE 182
QE RAKE L+ +RKR++ ++ L Q + L ++ + ++++ + + +E E
Sbjct: 696 QERNRAKETLEE---ERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELE 752
Query: 183 DAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKEL-EAELAMAKQ 239
+ LA++K++LE +R+AKEA + L+ + KE+ E+ +A K+
Sbjct: 753 ER---LARQKEVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKR 807
Score = 39.7 bits (91), Expect = 0.005
Identities = 55/237 (23%), Positives = 99/237 (41%), Gaps = 45/237 (18%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDL-------EESQGGKSSEVLSATELRVQLAQKEQE 124
L +++ +EE+ L Q +++L L EE+Q K++E L A L ++L + E
Sbjct: 823 LENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAE 882
Query: 125 LARAK-----------------EALQ-AMKADRKRLKGEKTDLVSQMQQLYATLESREEQ 166
L K +ALQ ++ R + E + Q++Q T+ S EE+
Sbjct: 883 LETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTIVSLEEK 942
Query: 167 LRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNR 226
L + QH K+ E + L K+ D +E + D A ++ KD
Sbjct: 943 L----QKVTQHHKKIEGEIATL-KDNDPAPKE--------ERPQDPLVAPMTESSAKDMA 989
Query: 227 MKELEAELAMAKQSLAT-------LTKDVPKRHSLAMPGETVLNGNQEWVVQADLPL 276
+ L +L A++ + + L KD+ + HS LN Q+ ++ ++ L
Sbjct: 990 YEHLIDDLLAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVL 1046
Score = 33.1 bits (74), Expect = 0.48
Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 12/105 (11%)
Query: 74 EEVSRLQEEV-HLLRQMKEMLAKDLE-ESQGGKSS---EVLSATELRVQLAQ-KEQELAR 127
E+V +L+EEV HL Q K+ KD + E+ G + S E L + +L + +E+EL
Sbjct: 361 EQVQQLKEEVSHLKSQNKD---KDHQLEALGSRCSVLKEELKQEDAHRELREAQEKELKL 417
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESR---EEQLRD 169
K +Q M+ + K+L+ E ++ + TL + EE+L++
Sbjct: 418 CKTQIQDMEKEMKKLRAELRKSCTEQSVISRTLREKSKVEEKLQE 462
Score = 32.7 bits (73), Expect = 0.62
Identities = 48/212 (22%), Positives = 82/212 (38%), Gaps = 33/212 (15%)
Query: 53 PRAGVPRVRADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLA---KDLEESQGGKSSEVL 109
P +G+ +V D +LR +S L+E LLR + + + KD + G S+
Sbjct: 597 PVSGLQKVVLD-------VLRHALSWLEEVEQLLRDLGILPSSPNKDQVQQFSGNSAVFT 649
Query: 110 SATELRVQLAQKEQEL--ARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL 167
+ + E E ARA+ Q+ +G K + Y T E +
Sbjct: 650 AGKAAGASGREGEAERGEARARGEAQSQNQATDGREGGKA------LEEYITQERNRAK- 702
Query: 168 RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 227
E+ RK ++ LA++K L AK T ++ L+ + R+
Sbjct: 703 ----ETLEEERKRMQELESLLAQQKKAL----------AKSITQEKNRVKEALEEEQTRV 748
Query: 228 KELEAELAMAKQSLATLTKDVPKRHSLAMPGE 259
+ELE LA K+ L + ++ A+ E
Sbjct: 749 QELEERLARQKEVLESSIAHEKRKAKEALESE 780
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 60.8 bits (146), Expect = 2e-09
Identities = 57/238 (23%), Positives = 117/238 (49%), Gaps = 20/238 (8%)
Query: 27 AGAGPARPP---GPAACEQCVDAAGPGDRPRAGVPRVRADGDCSQPVLLRE-EVSRLQEE 82
AGA P P GP C + +DAA PG R G + R P E +++ Q++
Sbjct: 651 AGARPGSLPERKGPELCLEELDAAIPGSRAVGG-SKARVQARQVPPATASEWRLAQAQQK 709
Query: 83 VHLLR---QMKEMLAKDLEESQGGKSSEVLSAT------ELRVQLAQKEQELARAKEALQ 133
+ L +MKE L +L + GK+++ L+ EL + Q EL+ + L+
Sbjct: 710 IRELAINIRMKEELIGELVRT--GKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLR 767
Query: 134 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQH---RKESEDAVKALAK 190
++ + GE++ L + ++ A +S+ + L++ + E+ +SE ++ L +
Sbjct: 768 ELEGKELQDAGERSRL-QEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELER 826
Query: 191 EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 248
L+ +++ +L+R+ +E T+ L +++ + +R+KELE + ++ L T+++
Sbjct: 827 NVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEI 884
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 60.5 bits (145), Expect = 3e-09
Identities = 89/342 (26%), Positives = 147/342 (42%), Gaps = 48/342 (14%)
Query: 2 RAADSGSWERVRQLAAQGEPAP----SCGAGAGPARPPGPAACEQCVDAA--GPGDRPRA 55
R AD+ + +R L+ Q P+P S G G P R P PA + A + +
Sbjct: 475 RTADASNGS-LRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQL 533
Query: 56 GVPRVRADGDCSQPVL--LREEVSRLQEEVHLLRQMKEML------AKDLEESQGGKSSE 107
V +R + SQ +L LR+++S + E L + + L A E +
Sbjct: 534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 593
Query: 108 VLSATEL----------RVQLAQKE-QELARAKEALQA----MKADRKRLKGEKTDLVSQ 152
+ SA EL +Q+AQ++ +EL + +E LQA ++ R RL+ E+ D V
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 153 MQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAK---EKDLLEREKWELRRQAKEA 209
++ LE QL KE + +AL++ ++D+L+ EK E+ EA
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEV----AEA 709
Query: 210 TDHATALRSQLDLKDNRMKELEA-------ELAMAKQSLATLTKDVPKRHSLAMPGETVL 262
A A R +L+L +++ EA +L+ +SLA D+ + + ++ L
Sbjct: 710 LTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSAL 769
Query: 263 NGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVS 304
G Q QA+ T A R+ Q+ L RQ + S
Sbjct: 770 QGRQR---QAEQEATVA-REEQERLEELRLEQEVARQGLEGS 807
Score = 48.9 bits (115), Expect = 8e-06
Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 24/183 (13%)
Query: 75 EVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEV------------LSATELRVQLAQKE 122
E R Q + L R+ +E+LA+ LE + S E+ L+ +E + L+ KE
Sbjct: 1010 EAERAQLQSQLQREQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKE 1068
Query: 123 QELARAKEALQAMKADRK----RLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHR 178
E E L + ++ +K D S+ +Q +T+ + +LRD R
Sbjct: 1069 SEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL-------R 1121
Query: 179 KESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAK 238
+ E+A A A+E L+ + +L +Q A LR+QL L ++ L EL A+
Sbjct: 1122 AQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQ 1181
Query: 239 QSL 241
+ L
Sbjct: 1182 RKL 1184
Score = 45.4 bits (106), Expect = 9e-05
Identities = 69/279 (24%), Positives = 115/279 (41%), Gaps = 54/279 (19%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKD----------LEES----QGGKSSEVLSATELRVQ 117
LR E + LQ+ + L + E LA+D LEE QG + AT R +
Sbjct: 727 LRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREE 786
Query: 118 LAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR----- 172
+ E+ + A Q ++ + + + L Q+ L +EQL R
Sbjct: 787 QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGR 846
Query: 173 --NYEQHRKESEDAVKAL---AKEKDLLEREKWEL-------RRQAKEATDHATALR--- 217
EQ R+E++ V+AL A+EK+ L +E L R+ + ++ AT LR
Sbjct: 847 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 906
Query: 218 -----------SQLDLKDNRMKELEAE---LAMAKQSLATLTKDVPKRHSLAMPGETVLN 263
QL + R ++LEAE L +AK+ TLT ++ + + +
Sbjct: 907 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKE---TLTGELAGLRQQIIATQEKAS 963
Query: 264 GNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVR 302
++E + Q L A R++Q +L H D Q ++
Sbjct: 964 LDKELMAQ---KLVQAEREAQASLREQRAAHEEDLQRLQ 999
Score = 45.4 bits (106), Expect = 9e-05
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 34/254 (13%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA 131
LR+++ QE+ L +++ E E +A E +Q Q+E+E A
Sbjct: 951 LRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKE-----AA 1005
Query: 132 LQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKES---------- 181
+ ++A+R +L+ + L + ++L A LE+ +E+L + I +Q R E
Sbjct: 1006 WRELEAERAQLQSQ---LQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQ 1062
Query: 182 ----EDAVKALAKEKDL----------LEREKWELRRQAKEATDHATALRSQLDLKDNRM 227
+++ K EK + LE E+ + Q+++ D +T +L+D R
Sbjct: 1063 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRA 1122
Query: 228 KELEAELAMAKQ--SLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 285
+ EA A A++ L +D+ K+ + L + A L + ++Q+
Sbjct: 1123 QREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQR 1182
Query: 286 TLYHSHPPHPADRQ 299
L S RQ
Sbjct: 1183 KLRESQEGREVQRQ 1196
Score = 43.5 bits (101), Expect = 4e-04
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 24/184 (13%)
Query: 75 EVSRLQEEVHLLRQMKEMLAKDL-------EESQGGKSSEVLSATELRVQL---AQKEQE 124
E L+ ++ LL ++ L ++L ESQ G+ + A ELR L A++ +
Sbjct: 1155 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA 1214
Query: 125 LARAKEALQA--MKADRKRL-----KGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQH 177
L R+ E L++ KA+ +R+ +K ++ +++ + +LR ++ E+
Sbjct: 1215 LRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1274
Query: 178 RKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMA 237
R E+ ++ L ++ +L+ E L R+ E L+ +L L + KE E
Sbjct: 1275 RLEARRELQELRRQMKMLDSENTRLGRELAE-------LQGRLALGERAEKESRRETLGL 1327
Query: 238 KQSL 241
+Q L
Sbjct: 1328 RQRL 1331
Score = 42.7 bits (99), Expect = 6e-04
Identities = 70/304 (23%), Positives = 119/304 (39%), Gaps = 53/304 (17%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSS---------EVLSATE-----LRVQ 117
L +++++E LR L + L +S +S + L+A E L+ +
Sbjct: 1710 LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQER 1769
Query: 118 LAQKEQELARAKEALQAMKADRKRLKGEKTDLV-------SQMQQLYATLESREE---QL 167
L Q L+ A++ ++ + L+GE DL Q+QQL L R+E
Sbjct: 1770 LDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAA 1829
Query: 168 RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLD------ 221
+ ++ + R+ ++ + +L + LE EK E+ R A ALR LD
Sbjct: 1830 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREK 1889
Query: 222 ---------------LKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQ 266
D + E ELA A++ + L V P + ++ Q
Sbjct: 1890 LRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQ 1949
Query: 267 EWV-VQADLP-LTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDR 324
+ + +Q ++ L +A Q+++TL H RQ VR Q S + E R
Sbjct: 1950 QQLELQQEVERLRSAQAQTERTLEARERAH---RQRVRGL---EEQVSTLKGQLQQELRR 2003
Query: 325 SSTP 328
SS P
Sbjct: 2004 SSAP 2007
Score = 40.8 bits (94), Expect = 0.002
Identities = 37/178 (20%), Positives = 76/178 (42%), Gaps = 11/178 (6%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 133
+EV RLQE+ L + ++ ++ EE + + LR +L + +++L ++E +
Sbjct: 1133 QEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGRE 1192
Query: 134 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHR-------KESEDAVK 186
+ + L+ + + + L E+LR ++ E R ++ E +
Sbjct: 1193 VQRQEAGELRRSLGEGAKERE----ALRRSNEELRSAVKKAESERISLKLANEDKEQKLA 1248
Query: 187 ALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 244
L + + + +E ELR +E R +L +MK L++E + LA L
Sbjct: 1249 LLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAEL 1306
Score = 39.7 bits (91), Expect = 0.005
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 9/196 (4%)
Query: 72 LREEVSRLQEEVH---LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARA 128
L EE++ LQ+E LL + ++ A L+ES+ SE L T R LA E+ R
Sbjct: 1038 LSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGT--RHSLATISLEMERQ 1095
Query: 129 KEALQA-MKADRKR---LKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDA 184
K Q+ + DR L E DL +Q ++ A +L++ R+ + R
Sbjct: 1096 KRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLRE 1155
Query: 185 VKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 244
+ L + LLE + LRR+ EA + +++ EL L + L
Sbjct: 1156 AEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Query: 245 TKDVPKRHSLAMPGET 260
+ + S E+
Sbjct: 1216 RRSNEELRSAVKKAES 1231
Score = 38.5 bits (88), Expect = 0.011
Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 19/193 (9%)
Query: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSAT-ELRVQLAQKEQEL 125
S+ L E++ + + + E +D + Q S V + T ELR AQ+E+
Sbjct: 1069 SEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1128
Query: 126 ARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATL---ESR-----------EEQLRDFI 171
A + ++ ++ + L ++ + + ++L L E + +LR+
Sbjct: 1129 AAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQ 1188
Query: 172 RNYEQHRKESEDAVKAL---AKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK 228
E R+E+ + ++L AKE++ L R ELR K+A +L+ + K+ ++
Sbjct: 1189 EGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLA 1248
Query: 229 EL-EAELAMAKQS 240
L EA A+ K++
Sbjct: 1249 LLEEARTAVGKEA 1261
Score = 34.3 bits (77), Expect = 0.21
Identities = 48/220 (21%), Positives = 90/220 (40%), Gaps = 48/220 (21%)
Query: 66 CSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKE--- 122
C + L ++++ + L ++E++ ++L + + S +L ATE+ L+ +E
Sbjct: 28 CQEKGLGARDLAQDAQITSLPALIREIVTRNLSQPE---SPVLLPATEMASLLSLQEENQ 84
Query: 123 ---QELARAKEALQAMKADRKRL-----------------------KGEKTDLVSQMQQL 156
QEL+R ++ L +A+R L E LV Q +L
Sbjct: 85 LLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVEL 144
Query: 157 YATLESREEQLRDFIRNYEQHRKESEDAVKAL------------AKEKDLLEREKWELRR 204
L+ + R ++ Y++ ++ V+ L E+ LLER EL +
Sbjct: 145 RRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLER-SGELEQ 203
Query: 205 QAKEATDHATALRS---QLDLKDNRMKELEAELAMAKQSL 241
Q T+H+ L S +L+ + R L AM ++ L
Sbjct: 204 QRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQL 243
Score = 33.5 bits (75), Expect = 0.36
Identities = 29/152 (19%), Positives = 66/152 (43%), Gaps = 4/152 (2%)
Query: 95 KDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 154
+ + S+ + + + L L E EL ++E + MKA+ +L+G+K +++
Sbjct: 1586 ESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDK----RRLK 1641
Query: 155 QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 214
++ ESR +L R+ E + S + + L+ L+RQ ++ A
Sbjct: 1642 EVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAG 1701
Query: 215 ALRSQLDLKDNRMKELEAELAMAKQSLATLTK 246
L+ ++ + + ++E + + LT+
Sbjct: 1702 TLQLTVERLNGALAKVEESEGALRDKVRGLTE 1733
Score = 29.3 bits (64), Expect = 6.9
Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 27/172 (15%)
Query: 88 QMKEMLAKDLEESQGGKSSEVL-------SATELRVQLAQKEQELARAKEALQAMKADRK 140
++++ +D E SQ +S+ + SA+ +V +EQ L +A A QA+ D +
Sbjct: 200 ELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQ-LDQAGSANQALSEDIR 258
Query: 141 RLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHR-----------KESEDAVKALA 189
++ + T +++ A EE + N E R + VK +
Sbjct: 259 KVTNDWTRCRKELEHREAAWRREEESFNAYFSN-EHSRLLLLWRQVVGFRRLVSEVK-MF 316
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
E+DLL+ EL R ++ + L + L R+ E AE A+ KQ+L
Sbjct: 317 TERDLLQL-GGELARTSRAVQEAGLGLSTGL-----RLAESRAEAALEKQAL 362
Score = 28.9 bits (63), Expect = 9.0
Identities = 29/120 (24%), Positives = 49/120 (40%), Gaps = 3/120 (2%)
Query: 52 RPRAGVPRVRADGDCSQPVLLRE---EVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEV 108
R G+ + G+ S V+ +E +LQE+ R + L LEE++G + ++
Sbjct: 1322 RETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQL 1381
Query: 109 LSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 168
A L ++L E A L A + + L+ E + Q + A L LR
Sbjct: 1382 DHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALR 1441
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 59.3 bits (142), Expect = 6e-09
Identities = 58/230 (25%), Positives = 106/230 (46%), Gaps = 37/230 (16%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA-- 131
+E+ + QE+ ++ + AK EE + E A++ Q+A+KE+EL+R KE
Sbjct: 1293 QEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQ-EEQIARKEEELSRVKERVV 1351
Query: 132 ------------------------------LQAMKADRKRLKGEKTDLVSQMQQLYATLE 161
+ ++A+ +RL+ +T+L Q+++L +
Sbjct: 1352 QQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQ 1411
Query: 162 SREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLD 221
+R E R+ R Q R + + +A A+EK + +K L++ ++A +HA LR QL+
Sbjct: 1412 ARREAEREVQR--LQQRLAALEQEEAEAREK-VTHTQKVVLQQDPQQAREHA-LLRLQLE 1467
Query: 222 LKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQ 271
+ +R + LE EL ++ LA L K K + V G+ E +Q
Sbjct: 1468 EEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQ 1517
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/187 (26%), Positives = 86/187 (45%), Gaps = 22/187 (11%)
Query: 71 LLREEVSRLQEEVHLLRQ----------MKEMLAKDLEESQGGKSSEVLSATE-LRVQLA 119
LL+EE+ LQ ++ L Q +KE+L + + +Q + ++ E LR Q
Sbjct: 966 LLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKG 1025
Query: 120 QKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRK 179
+E E+ ++ + A+ ++ R + + T+ Q LE+ +QL++ + +Q R+
Sbjct: 1026 AREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLRE 1085
Query: 180 ESE-------DAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 232
+ E D +K L KE+ + E K ++ K D AT R DL R E EA
Sbjct: 1086 KQEEELSFLQDKLKRLEKERAMAE-GKITVKEVLKVEKDAATE-REVSDL--TRQYEDEA 1141
Query: 233 ELAMAKQ 239
A A Q
Sbjct: 1142 AKARASQ 1148
Score = 35.0 bits (79), Expect = 0.13
Identities = 36/179 (20%), Positives = 78/179 (43%), Gaps = 16/179 (8%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA 131
L+ + + L E ++++++ A + Q K E L A +LR L + + +
Sbjct: 767 LKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYE-LEAEKLRSLLDLENGRSSHVSKR 825
Query: 132 LQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKE 191
+ +++ ++K E+ L ++ ++YA R + L +F N + + E E + L
Sbjct: 826 AR-LQSPATKVKEEEAALAAKFTEVYAINRQRLQNL-EFALNLLRQQPEVEVTHETLQ-- 881
Query: 192 KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK 250
R + + A +R +LD + R ++LE E+ ++ + TL P+
Sbjct: 882 -----------RNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQ 929
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/185 (25%), Positives = 87/185 (47%), Gaps = 15/185 (8%)
Query: 82 EVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKR 141
E L R + ++ E S+ + ++L +LR Q K Q LA ++ ++ K R+R
Sbjct: 349 ESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR 408
Query: 142 LKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE 201
L+ ++ +Q RE++ + + E+ RKE E+ +A +EK +ERE+
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEY 467
Query: 202 LRRQAKEATDHATALRSQL-------------DLKDNRMKE-LEAELAMAKQSLATLTKD 247
+RRQ +E H L+ QL +++++R E L+ +L + L +L D
Sbjct: 468 IRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHD 527
Query: 248 VPKRH 252
+ H
Sbjct: 528 HRRPH 532
Score = 36.6 bits (83), Expect = 0.043
Identities = 87/375 (23%), Positives = 136/375 (36%), Gaps = 70/375 (18%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 133
EE R +EE + + +E + + LEE Q + EVL L+ Q E +E Q
Sbjct: 449 EERRRAEEEKRRVEREQEYIRRQLEEEQ--RHLEVLQQQLLQEQAMLLECRWREMEEHRQ 506
Query: 134 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
A + R Q+QQ A L S + D R + QH ++
Sbjct: 507 AERLQR------------QLQQEQAYLLSLQ---HDHRRPHPQHSQQPPPP--------- 542
Query: 194 LLEREKWELRRQAKEATDHATALRSQLDLKDN-RMKELEAELAMAKQSLATLTKDVPKRH 252
++E+ + A E H +++D R + A +KQ+ L VP R
Sbjct: 543 --QQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSR- 599
Query: 253 SLAMPGETVLNGNQEWV---------VQADLPLTAAIRQSQQTLYHSH-----PPHPADR 298
E+ NGN E V Q A+++ + + SH P A
Sbjct: 600 -----SESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHH 654
Query: 299 QAVRVSPCHSRQPSVISDASAAEGDR--------SSTPSDINSPR------HRTHSLCNG 344
PC + V+S +S ++ + S + SD PR R+ L
Sbjct: 655 HLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRR 714
Query: 345 DSP--GPVQKNLHNPIVQSLEDLEDQKRKKKKEKM----GFGSISRVFARGKQRKSLDPG 398
DSP G Q+N S +E + ++ EK+ G GS S G Q S PG
Sbjct: 715 DSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGS-HPG 773
Query: 399 LFDGTAPDYYIEEDA 413
G+ + + +
Sbjct: 774 SQSGSGERFRVRSSS 788
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 57.4 bits (137), Expect = 2e-08
Identities = 49/207 (23%), Positives = 91/207 (43%), Gaps = 21/207 (10%)
Query: 71 LLREEVSRLQ---EEVHLLRQMKEMLAKDLEESQGGKSSEV------LSATELRV----- 116
+L+ EV L+ EE + K +D+ E +G ++ E+ L E +V
Sbjct: 519 ILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQK 578
Query: 117 -------QLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRD 169
QL KE++++ KE +++++AD T L + + T+E +EQ
Sbjct: 579 KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDR 638
Query: 170 FIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKE 229
R ++ + +K L ++ LL+ + E + +HA++L S KD+R+K
Sbjct: 639 DEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKT 698
Query: 230 LEAELAMAKQSLATLTKDVPKRHSLAM 256
LE L K+ + + K H A+
Sbjct: 699 LEIALEQKKEECLKMESQLKKAHEAAL 725
Score = 47.0 bits (110), Expect = 3e-05
Identities = 62/253 (24%), Positives = 111/253 (43%), Gaps = 39/253 (15%)
Query: 73 REEVSRLQEEVHLLR---QMKEMLAKDLEESQGGKSSEVLSATE----LRVQLAQKEQE- 124
++++ L+E+V LL+ KE DL+E +S L L + L QK++E
Sbjct: 651 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEEC 710
Query: 125 ------LARAKEA-------------LQAMKADRKRLKGEKTDLVSQMQQLYATLESREE 165
L +A EA +Q ++ + R K E + +++ +L L+ E
Sbjct: 711 LKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVEN 770
Query: 166 QLRDFIRNYEQHRKESEDAVKALA--KEKDLLEREKW-----ELRRQAKEATDHATALRS 218
+ D + + ++ +D K +A K K+ +E++K E RR+ D + L+
Sbjct: 771 EKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD 830
Query: 219 QLDLKDNRMKELEAELAMAKQSLA----TLTKDVPKRHSLAMPGETVLNGNQEWVVQADL 274
L KD+R++ELE L + Q A L ++ R + E +L E V Q
Sbjct: 831 SLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMA-MEKVKQELE 889
Query: 275 PLTAAIRQSQQTL 287
+ A + +QQ+L
Sbjct: 890 SMKAKLSSTQQSL 902
Score = 42.4 bits (98), Expect = 8e-04
Identities = 48/227 (21%), Positives = 89/227 (39%), Gaps = 29/227 (12%)
Query: 41 EQCVDAAGPGDRPRAGVPRVRADGDCSQPVL-LREEVSRLQEEVHLLRQMKEMLAKDLEE 99
E+C+ + RA + S + L E++R ++E + + L + L+E
Sbjct: 708 EECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKE 767
Query: 100 SQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA-------DRKRLKGEKTDLVSQ 152
+ K+ + EL Q+ + +++A K Q K + +R + D Q
Sbjct: 768 VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQ 827
Query: 153 MQQLYATLESREEQLRDFIRNYEQ------------------HRKESEDAVKALAKEKDL 194
+Q + R E+L + +R Q K+ E+ + A+ K K
Sbjct: 828 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 887
Query: 195 LEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
LE K +L + + T L +L+ R K LE L M +++L
Sbjct: 888 LESMKAKLSSTQQSLAEKETHL---TNLRAERRKHLEEVLEMKQEAL 931
Score = 38.5 bits (88), Expect = 0.011
Identities = 40/190 (21%), Positives = 88/190 (46%), Gaps = 18/190 (9%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQ---ELARAKEAL 132
+ LQ+E+ + R + ++ +D G L+ + A+ E+ EL ++ L
Sbjct: 229 IQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTL 288
Query: 133 QAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEK 192
+ M+ + K +++L L+S+ + ++E+ R+ +E + E
Sbjct: 289 EEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLES 348
Query: 193 DLLEREKW------ELRRQAKEATDHAT--ALRSQLDLKDNR-------MKELEAELAMA 237
L ++EK E+ R+ + A D A AL++ +++KD++ +++LE E+ M
Sbjct: 349 LLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQML 408
Query: 238 KQSLATLTKD 247
K + A T++
Sbjct: 409 KSNGALSTEE 418
Score = 38.1 bits (87), Expect = 0.015
Identities = 50/249 (20%), Positives = 106/249 (42%), Gaps = 26/249 (10%)
Query: 74 EEVSRLQEEVH-LLRQMKEMLAKD---LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
EE R ++ ++ +Q+++ L K +EE + V E + LAQ+E A+
Sbjct: 812 EEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAE 871
Query: 130 EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE----SEDAV 185
+ ++ + +++K E + +++ +L +E L + +H +E ++A+
Sbjct: 872 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEAL 931
Query: 186 KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLT 245
A EKD EL K+ + AL+ + KD +++L+ + + +A
Sbjct: 932 LAAISEKD-ANIALLELSSSKKKTQEEVAALKRE---KDRLVQQLKQQTQNRMKLMADNY 987
Query: 246 KDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSP 305
+D + S + +T + + ++Q L L +S+ LY H +
Sbjct: 988 EDDHFKSSHS--NQTNHKPSPDQIIQPLLELDQ--NRSKLKLYIGH----------LTTL 1033
Query: 306 CHSRQPSVI 314
CH R P ++
Sbjct: 1034 CHDRDPLIL 1042
Score = 35.8 bits (81), Expect = 0.073
Identities = 40/194 (20%), Positives = 76/194 (39%), Gaps = 17/194 (8%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKE---QELARA 128
L EE+ L+ L + +E K +E + +L+ +L+ KE +EL +
Sbjct: 401 LEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKK 460
Query: 129 KEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKAL 188
LQA K+ K + +Q TL ++ + I ++ E L
Sbjct: 461 AAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAIL 520
Query: 189 AKEKDL----LEREKWELRRQAKEATDHATA----------LRSQLDLKDNRMKELEAEL 234
E D LE ++ L ++ K+ D A L+ LD+K+ ++ L+ ++
Sbjct: 521 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKI 580
Query: 235 AMAKQSLATLTKDV 248
++ L K +
Sbjct: 581 ENLQEQLRDKEKQM 594
Score = 34.7 bits (78), Expect = 0.16
Identities = 44/190 (23%), Positives = 80/190 (42%), Gaps = 36/190 (18%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQ-----LAQKEQELARA 128
E + +L E + Q K + AK EE + + L+ E+ V L QKE+E +
Sbjct: 307 ESIKKLLE----MLQSKGLSAKATEEDH--ERTRRLAEAEMHVHHLESLLEQKEKENSML 360
Query: 129 KEALQAM---KADRKRLKGEKT-----------------DLVSQMQQLYA----TLESRE 164
+E + D + K +T DL ++Q L + + E RE
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 165 EQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKD 224
E+++ + Y H K ++ V+ L +E E + EL+++A ++ +L KD
Sbjct: 421 EEMKQ-MEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKD 479
Query: 225 NRMKELEAEL 234
+ L+ +L
Sbjct: 480 TELLALQTKL 489
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 57.4 bits (137), Expect = 2e-08
Identities = 49/207 (23%), Positives = 91/207 (43%), Gaps = 21/207 (10%)
Query: 71 LLREEVSRLQ---EEVHLLRQMKEMLAKDLEESQGGKSSEV------LSATELRV----- 116
+L+ EV L+ EE + K +D+ E +G ++ E+ L E +V
Sbjct: 491 ILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQK 550
Query: 117 -------QLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRD 169
QL KE++++ KE +++++AD T L + + T+E +EQ
Sbjct: 551 KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDR 610
Query: 170 FIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKE 229
R ++ + +K L ++ LL+ + E + +HA++L S KD+R+K
Sbjct: 611 DEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKT 670
Query: 230 LEAELAMAKQSLATLTKDVPKRHSLAM 256
LE L K+ + + K H A+
Sbjct: 671 LEIALEQKKEECLKMESQLKKAHEAAL 697
Score = 47.0 bits (110), Expect = 3e-05
Identities = 62/253 (24%), Positives = 111/253 (43%), Gaps = 39/253 (15%)
Query: 73 REEVSRLQEEVHLLR---QMKEMLAKDLEESQGGKSSEVLSATE----LRVQLAQKEQE- 124
++++ L+E+V LL+ KE DL+E +S L L + L QK++E
Sbjct: 623 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEEC 682
Query: 125 ------LARAKEA-------------LQAMKADRKRLKGEKTDLVSQMQQLYATLESREE 165
L +A EA +Q ++ + R K E + +++ +L L+ E
Sbjct: 683 LKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVEN 742
Query: 166 QLRDFIRNYEQHRKESEDAVKALA--KEKDLLEREKW-----ELRRQAKEATDHATALRS 218
+ D + + ++ +D K +A K K+ +E++K E RR+ D + L+
Sbjct: 743 EKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD 802
Query: 219 QLDLKDNRMKELEAELAMAKQSLA----TLTKDVPKRHSLAMPGETVLNGNQEWVVQADL 274
L KD+R++ELE L + Q A L ++ R + E +L E V Q
Sbjct: 803 SLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMA-MEKVKQELE 861
Query: 275 PLTAAIRQSQQTL 287
+ A + +QQ+L
Sbjct: 862 SMKAKLSSTQQSL 874
Score = 42.4 bits (98), Expect = 8e-04
Identities = 48/227 (21%), Positives = 89/227 (39%), Gaps = 29/227 (12%)
Query: 41 EQCVDAAGPGDRPRAGVPRVRADGDCSQPVL-LREEVSRLQEEVHLLRQMKEMLAKDLEE 99
E+C+ + RA + S + L E++R ++E + + L + L+E
Sbjct: 680 EECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKE 739
Query: 100 SQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA-------DRKRLKGEKTDLVSQ 152
+ K+ + EL Q+ + +++A K Q K + +R + D Q
Sbjct: 740 VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQ 799
Query: 153 MQQLYATLESREEQLRDFIRNYEQ------------------HRKESEDAVKALAKEKDL 194
+Q + R E+L + +R Q K+ E+ + A+ K K
Sbjct: 800 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 859
Query: 195 LEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
LE K +L + + T L +L+ R K LE L M +++L
Sbjct: 860 LESMKAKLSSTQQSLAEKETHL---TNLRAERRKHLEEVLEMKQEAL 903
Score = 38.5 bits (88), Expect = 0.011
Identities = 40/190 (21%), Positives = 88/190 (46%), Gaps = 18/190 (9%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQ---ELARAKEAL 132
+ LQ+E+ + R + ++ +D G L+ + A+ E+ EL ++ L
Sbjct: 229 IQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTL 288
Query: 133 QAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEK 192
+ M+ + K +++L L+S+ + ++E+ R+ +E + E
Sbjct: 289 EEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLES 348
Query: 193 DLLEREKW------ELRRQAKEATDHAT--ALRSQLDLKDNR-------MKELEAELAMA 237
L ++EK E+ R+ + A D A AL++ +++KD++ +++LE E+ M
Sbjct: 349 LLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQML 408
Query: 238 KQSLATLTKD 247
K + A T++
Sbjct: 409 KSNGALSTEE 418
Score = 38.1 bits (87), Expect = 0.015
Identities = 50/249 (20%), Positives = 106/249 (42%), Gaps = 26/249 (10%)
Query: 74 EEVSRLQEEVH-LLRQMKEMLAKD---LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
EE R ++ ++ +Q+++ L K +EE + V E + LAQ+E A+
Sbjct: 784 EEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAE 843
Query: 130 EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE----SEDAV 185
+ ++ + +++K E + +++ +L +E L + +H +E ++A+
Sbjct: 844 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEAL 903
Query: 186 KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLT 245
A EKD EL K+ + AL+ + KD +++L+ + + +A
Sbjct: 904 LAAISEKD-ANIALLELSSSKKKTQEEVAALKRE---KDRLVQQLKQQTQNRMKLMADNY 959
Query: 246 KDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSP 305
+D + S + +T + + ++Q L L +S+ LY H +
Sbjct: 960 EDDHFKSSHS--NQTNHKPSPDQIIQPLLELDQ--NRSKLKLYIGH----------LTTL 1005
Query: 306 CHSRQPSVI 314
CH R P ++
Sbjct: 1006 CHDRDPLIL 1014
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 57.4 bits (137), Expect = 2e-08
Identities = 44/193 (22%), Positives = 93/193 (48%), Gaps = 17/193 (8%)
Query: 73 REEVSRLQEEVHLL-RQMKEM-LAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAK 129
+ E+ +L++++ +Q+K + + K+ E S+ + L EL++ L + E+++ K
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 800
Query: 130 EAL----QAMKADRKRLKGEKTDLVSQMQQLYATLESREEQ----------LRDFIRNYE 175
E L Q +K E + MQ+ L +EEQ LR+ + + E
Sbjct: 801 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 860
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
+E ++ + L K K+ LE + E+ + + + + T + +L LK+ ++EL+ +L
Sbjct: 861 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLT 920
Query: 236 MAKQSLATLTKDV 248
A ++ + L K +
Sbjct: 921 KANENASFLQKSI 933
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Query: 75 EVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQA 134
+++++ +E+ L + E L L ++ S S ++ V+ Q +QE A+ E
Sbjct: 897 QLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE--- 953
Query: 135 MKADRKRLKGEKTDLVSQM-------QQLYATLESREEQLR----DFIRNYEQHRKESED 183
++K L+ + +DL +M Q+L A E + + + ++N ++ ++ED
Sbjct: 954 ---EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTED 1010
Query: 184 AVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLAT 243
+K +E L +E ELR+QA +A TA + + + KE LA + + T
Sbjct: 1011 KLKGAREENSGLLQELEELRKQADKAKAAQTA-EDAMQIMEQMTKEKTETLASLEDTKQT 1069
Query: 244 LTK 246
K
Sbjct: 1070 NAK 1072
Score = 42.7 bits (99), Expect = 6e-04
Identities = 42/179 (23%), Positives = 88/179 (49%), Gaps = 18/179 (10%)
Query: 79 LQEEVHLLRQMKE---MLAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEALQA 134
+QE V+ L Q +E ML+ DLE K E L+ E + + ++E++L +AKE L+
Sbjct: 828 MQETVNKLHQKEEQFNMLSSDLE-----KLRENLADMEAKFREKDEREEQLIKAKEKLEN 882
Query: 135 MKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQH----RKESED-AVKALA 189
A+ ++ G+ + +++M E E+L+ + ++ +K ED VKA
Sbjct: 883 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQ 942
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 248
+++ ++ + E + ++ +D L +++ N+ +EL+A A T +++
Sbjct: 943 SQQEAAKKHEEEKKELERKLSD----LEKKMETSHNQCQELKARYERATSETKTKHEEI 997
Score = 38.1 bits (87), Expect = 0.015
Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 9/157 (5%)
Query: 95 KDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 154
+D E + K E L A ++V + +KE L + L KA+ + L E D ++++Q
Sbjct: 635 QDSERAAHAKEMEALRAKLMKV-IKEKENSLEAIRSKLD--KAEDQHLV-EMEDTLNKLQ 690
Query: 155 QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 214
+ A ++ +E ++ N EQ + + A E+ LL+ + LR+ + E
Sbjct: 691 E--AEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDA--LRKASSEGKSEMK 745
Query: 215 ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKR 251
LR QL+ + ++K LE E +++T+++ R
Sbjct: 746 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR 782
Score = 37.0 bits (84), Expect = 0.033
Identities = 45/196 (22%), Positives = 84/196 (42%), Gaps = 28/196 (14%)
Query: 64 GDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGK----SSEVLSATELRVQLA 119
GD + L +E+S LQE++ + R + L+E G + E+ + +L+
Sbjct: 494 GDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLS 553
Query: 120 QKEQELARAKEALQAMKADRKRLKGEK--TDLVSQMQQL-----------------YATL 160
++ + L E +D L K T + S Q + +A L
Sbjct: 554 KENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAEL 613
Query: 161 ESREEQLR-DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ 219
+++ E++R D+ E + + + A AKE + L + +L + KE + A+RS+
Sbjct: 614 KTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEAL---RAKLMKVIKEKENSLEAIRSK 670
Query: 220 LD-LKDNRMKELEAEL 234
LD +D + E+E L
Sbjct: 671 LDKAEDQHLVEMEDTL 686
Score = 34.3 bits (77), Expect = 0.21
Identities = 31/140 (22%), Positives = 61/140 (43%)
Query: 112 TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFI 171
TE + A+K +EAL+ + ++L E+ +++ + + + E++L
Sbjct: 337 TETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR 396
Query: 172 RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 231
++QH E E + L + +REK EL Q +E L+ +++ + +LE
Sbjct: 397 DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE 456
Query: 232 AELAMAKQSLATLTKDVPKR 251
K + L KD+ R
Sbjct: 457 VATVSEKSRIMELEKDLALR 476
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 57.4 bits (137), Expect = 2e-08
Identities = 44/193 (22%), Positives = 93/193 (48%), Gaps = 17/193 (8%)
Query: 73 REEVSRLQEEVHLL-RQMKEM-LAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAK 129
+ E+ +L++++ +Q+K + + K+ E S+ + L EL++ L + E+++ K
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 835
Query: 130 EAL----QAMKADRKRLKGEKTDLVSQMQQLYATLESREEQ----------LRDFIRNYE 175
E L Q +K E + MQ+ L +EEQ LR+ + + E
Sbjct: 836 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 895
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
+E ++ + L K K+ LE + E+ + + + + T + +L LK+ ++EL+ +L
Sbjct: 896 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLT 955
Query: 236 MAKQSLATLTKDV 248
A ++ + L K +
Sbjct: 956 KANENASFLQKSI 968
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Query: 75 EVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQA 134
+++++ +E+ L + E L L ++ S S ++ V+ Q +QE A+ E
Sbjct: 932 QLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE--- 988
Query: 135 MKADRKRLKGEKTDLVSQM-------QQLYATLESREEQLR----DFIRNYEQHRKESED 183
++K L+ + +DL +M Q+L A E + + + ++N ++ ++ED
Sbjct: 989 ---EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTED 1045
Query: 184 AVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLAT 243
+K +E L +E ELR+QA +A TA + + + KE LA + + T
Sbjct: 1046 KLKGAREENSGLLQELEELRKQADKAKAAQTA-EDAMQIMEQMTKEKTETLASLEDTKQT 1104
Query: 244 LTK 246
K
Sbjct: 1105 NAK 1107
Score = 42.7 bits (99), Expect = 6e-04
Identities = 42/179 (23%), Positives = 88/179 (49%), Gaps = 18/179 (10%)
Query: 79 LQEEVHLLRQMKE---MLAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEALQA 134
+QE V+ L Q +E ML+ DLE K E L+ E + + ++E++L +AKE L+
Sbjct: 863 MQETVNKLHQKEEQFNMLSSDLE-----KLRENLADMEAKFREKDEREEQLIKAKEKLEN 917
Query: 135 MKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQH----RKESED-AVKALA 189
A+ ++ G+ + +++M E E+L+ + ++ +K ED VKA
Sbjct: 918 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQ 977
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 248
+++ ++ + E + ++ +D L +++ N+ +EL+A A T +++
Sbjct: 978 SQQEAAKKHEEEKKELERKLSD----LEKKMETSHNQCQELKARYERATSETKTKHEEI 1032
Score = 38.1 bits (87), Expect = 0.015
Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 9/157 (5%)
Query: 95 KDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 154
+D E + K E L A ++V + +KE L + L KA+ + L E D ++++Q
Sbjct: 670 QDSERAAHAKEMEALRAKLMKV-IKEKENSLEAIRSKLD--KAEDQHLV-EMEDTLNKLQ 725
Query: 155 QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 214
+ A ++ +E ++ N EQ + + A E+ LL+ + LR+ + E
Sbjct: 726 E--AEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDA--LRKASSEGKSEMK 780
Query: 215 ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKR 251
LR QL+ + ++K LE E +++T+++ R
Sbjct: 781 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR 817
Score = 37.7 bits (86), Expect = 0.019
Identities = 33/161 (20%), Positives = 69/161 (42%), Gaps = 6/161 (3%)
Query: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELA 126
+Q L + L++ + + + L ++LE+++ SE EL LA + QE+A
Sbjct: 457 TQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVA 516
Query: 127 RAKEALQAMK--ADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDA 184
+ L++ K D ++ S ++L T + ++ ++ + +
Sbjct: 517 ELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKE 576
Query: 185 VKALAKEKDLLERE----KWELRRQAKEATDHATALRSQLD 221
+KAL + L +E K +L KE +D +S+L+
Sbjct: 577 IKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLE 617
Score = 37.0 bits (84), Expect = 0.033
Identities = 45/196 (22%), Positives = 84/196 (42%), Gaps = 28/196 (14%)
Query: 64 GDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGK----SSEVLSATELRVQLA 119
GD + L +E+S LQE++ + R + L+E G + E+ + +L+
Sbjct: 529 GDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLS 588
Query: 120 QKEQELARAKEALQAMKADRKRLKGEK--TDLVSQMQQL-----------------YATL 160
++ + L E +D L K T + S Q + +A L
Sbjct: 589 KENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAEL 648
Query: 161 ESREEQLR-DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ 219
+++ E++R D+ E + + + A AKE + L + +L + KE + A+RS+
Sbjct: 649 KTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEAL---RAKLMKVIKEKENSLEAIRSK 705
Query: 220 LD-LKDNRMKELEAEL 234
LD +D + E+E L
Sbjct: 706 LDKAEDQHLVEMEDTL 721
Score = 32.0 bits (71), Expect = 1.1
Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 14/151 (9%)
Query: 112 TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFI 171
TE + A+K +EAL+ + ++L E+ +++ + + + E++L
Sbjct: 337 TETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR 396
Query: 172 RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR-------------- 217
++QH E E + L + +REK EL Q +E L+
Sbjct: 397 DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE 456
Query: 218 SQLDLKDNRMKELEAELAMAKQSLATLTKDV 248
+Q L+ R+KELE L K L +++
Sbjct: 457 TQTKLEHARIKELEQSLLFEKTKADKLQREL 487
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 57.0 bits (136), Expect = 3e-08
Identities = 39/139 (28%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 82 EVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKR 141
E L R + ++ E S+ + ++L +LR Q K Q LA ++ ++ K R+R
Sbjct: 349 ESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR 408
Query: 142 LKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE 201
L+ ++ +Q RE++ + + E+ RKE E+ +A +EK +ERE+
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEY 467
Query: 202 LRRQAKEATDHATALRSQL 220
+RRQ +E H L+ QL
Sbjct: 468 IRRQLEEEQRHLEVLQQQL 486
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 57.0 bits (136), Expect = 3e-08
Identities = 39/139 (28%), Positives = 69/139 (49%), Gaps = 1/139 (0%)
Query: 82 EVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKR 141
E L R + ++ E S+ + ++L +LR Q K Q LA ++ ++ K R+R
Sbjct: 349 ESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR 408
Query: 142 LKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE 201
L+ ++ +Q RE++ + + E+ RKE E+ +A +EK +ERE+
Sbjct: 409 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEY 467
Query: 202 LRRQAKEATDHATALRSQL 220
+RRQ +E H L+ QL
Sbjct: 468 IRRQLEEEQRHLEVLQQQL 486
>gi|222537714 taxilin beta [Homo sapiens]
Length = 684
Score = 56.2 bits (134), Expect = 5e-08
Identities = 47/207 (22%), Positives = 96/207 (46%), Gaps = 24/207 (11%)
Query: 50 GDRPRAGVPRVRADGDCSQ-----PVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGK 104
G+ RA + R + + C + L E + R +EE +++ L + QG
Sbjct: 202 GEHSRAILARSKLESLCRELQRHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQG-- 259
Query: 105 SSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATL-ESR 163
++ +E ++L Q+ ELA +++ D+ L+ E D + + ++L L +++
Sbjct: 260 --QIEQQSERNMKLCQENTELAEKLKSI----IDQYELREEHLDKIFKHRELQQKLVDAK 313
Query: 164 EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLK 223
EQ ++ ++ E+ K +EK+ L + E + QAK + T L++QL L
Sbjct: 314 LEQAQEMMKEAEERHK----------REKEYLLNQAAEWKLQAKVLKEQETVLQAQLTLY 363
Query: 224 DNRMKELEAELAMAKQSLATLTKDVPK 250
R +E ++ L + + AT +++ K
Sbjct: 364 SGRFEEFQSTLTKSNEVFATFKQEMDK 390
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 55.8 bits (133), Expect = 7e-08
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 16/187 (8%)
Query: 71 LLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKE 130
L REE R +E+ R+ E + DL + +++ EL++QLA+KE+EL A
Sbjct: 1036 LRREEKQR--QELEKTRRKLEGDSTDLSDQIAELQAQI---AELKMQLAKKEEELQAALA 1090
Query: 131 ALQAMKADRKRLKGEKTDLVSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESED 183
++ A + + +L SQ+ +L LES E+Q RD E + E ED
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
Query: 184 AVKALAKEKDLLEREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 239
+ + A +++L + + E+ + +EA H ++ ++EL +L K+
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
Query: 240 SLATLTK 246
A L K
Sbjct: 1211 VKANLEK 1217
Score = 50.1 bits (118), Expect = 4e-06
Identities = 40/196 (20%), Positives = 83/196 (42%), Gaps = 4/196 (2%)
Query: 68 QPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
+ ++L ++ +L +E LL +L E + S + + E+ L R
Sbjct: 979 EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKA 187
++ Q ++ R++L+G+ TDL Q+ +L A + + QL E+ + + V+
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQL----AKKEEELQAALARVEE 1094
Query: 188 LAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
A +K++ ++ EL Q E + + R+ + + + ++L EL K L
Sbjct: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
Query: 248 VPKRHSLAMPGETVLN 263
+ L E +N
Sbjct: 1155 TAAQQELRSKREQEVN 1170
Score = 44.3 bits (103), Expect = 2e-04
Identities = 40/173 (23%), Positives = 82/173 (47%), Gaps = 10/173 (5%)
Query: 57 VPRVRADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGG-KSSEVLSATELR 115
+ ++ D + + + E +R Q E RQ KE+ K L+E +G KS S T L
Sbjct: 1759 IDQINTDLNLERSHAQKNENARQQLE----RQNKELKVK-LQEMEGTVKSKYKASITALE 1813
Query: 116 VQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYE 175
++AQ E++L + QA +R + + D++ Q+ E ++Q +
Sbjct: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK 228
Q +++ E+A +E + +L+R+ ++AT+ A A+ ++ N+++
Sbjct: 1874 QLKRQLEEA----EEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 43.9 bits (102), Expect = 3e-04
Identities = 38/174 (21%), Positives = 80/174 (45%), Gaps = 25/174 (14%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 133
EE+ +EE+ +R+ K++ A++ TE+ +Q E + +E LQ
Sbjct: 845 EEMMAKEEELVKVRE-KQLAAEN-------------RLTEMETLQSQLMAEKLQLQEQLQ 890
Query: 134 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
A +T+L ++ ++L A L +++++L + + E +E E+ + L EK
Sbjct: 891 A-----------ETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKK 939
Query: 194 LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
+++ EL Q +E L+ + + ++K+LE E + + L K+
Sbjct: 940 KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKE 993
Score = 42.4 bits (98), Expect = 8e-04
Identities = 44/211 (20%), Positives = 90/211 (42%), Gaps = 41/211 (19%)
Query: 59 RVRADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQL 118
R + +GD + L ++++ LQ ++ ++K LAK EE Q + A + + L
Sbjct: 1050 RRKLEGDSTD---LSDQIAELQAQI---AELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103
Query: 119 A---QKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESR------------ 163
+ E +++ +E L++ +A R + + +K DL +++ L LE
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Query: 164 -------------EEQLRDFIRNYEQHRKESEDAVKALAKE-------KDLLEREKWELR 203
EE+ + ++ R++ AV+ LA++ K LE+ K L
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 204 RQAKEATDHATALRSQLDLKDNRMKELEAEL 234
+ E + L +++ K++EA+L
Sbjct: 1224 NERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/185 (25%), Positives = 75/185 (40%), Gaps = 17/185 (9%)
Query: 77 SRLQEEVHLLRQ-MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM 135
+RL E L Q M E L L+E ++ A ELR +L K+QEL L+A
Sbjct: 866 NRLTEMETLQSQLMAEKL--QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEAR 923
Query: 136 KADRKR----LKGEKTDLVSQMQQLYATLESREEQLRDF----------IRNYEQHRKES 181
+ + L+ EK + +Q+L LE E + ++ E+ +
Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983
Query: 182 EDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
ED LAKEK LLE E E + + +L + + + +LE L ++
Sbjct: 984 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043
Query: 242 ATLTK 246
L K
Sbjct: 1044 QELEK 1048
Score = 40.4 bits (93), Expect = 0.003
Identities = 51/259 (19%), Positives = 107/259 (41%), Gaps = 41/259 (15%)
Query: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELA 126
++ + L+EE++ + +Q ++ LA ++ S G + + L ++AQ E+EL
Sbjct: 1680 AEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELE 1739
Query: 127 -----------RAKEA-----------------LQAMKADRKRLKGEKTDLVSQMQQLYA 158
R K+A Q + R++L+ + +L ++Q++
Sbjct: 1740 EEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEG 1799
Query: 159 TLESR--------EEQLRDFIRNYEQHRKESEDAVKAL----AKEKDLLEREKWELRRQA 206
T++S+ E ++ + KE + A K + K KD+L + E RR A
Sbjct: 1800 TVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE-RRNA 1858
Query: 207 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQ 266
++ D A ++L +++E E E A S L +++ A ++ +
Sbjct: 1859 EQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLK 1918
Query: 267 EWVVQADLPLTAAIRQSQQ 285
+ + DLP R +++
Sbjct: 1919 NKLRRGDLPFVVPRRMARK 1937
Score = 37.7 bits (86), Expect = 0.019
Identities = 45/196 (22%), Positives = 83/196 (42%), Gaps = 21/196 (10%)
Query: 72 LREEVSRLQEEVHLLRQMKEM----LAKDLEESQG-----GKSSEVLS------ATELRV 116
L EE + ++ +RQ LA+ LE+++ K+ + L A E++V
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 117 QLAQK-EQELARAKEALQAMKADRKRLKGE--KTDLVSQMQQLYATLESREEQLRDFIRN 173
L K + E R K Q + K +GE +T+L ++ +L L++ L
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
Query: 174 YEQHRKESEDAVKALAKEKDLLE---REKWELRRQAKEATDHATALRSQLDLKDNRMKEL 230
+ K+ L ++LL+ R+K L + K+ D + R QL+ ++ L
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL 1355
Query: 231 EAELAMAKQSLATLTK 246
E ++A +A + K
Sbjct: 1356 EKQIATLHAQVADMKK 1371
Score = 36.2 bits (82), Expect = 0.056
Identities = 45/191 (23%), Positives = 81/191 (42%), Gaps = 28/191 (14%)
Query: 75 EVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQA 134
E ++L+ EV+L + MK +DL QG +L Q+ + E EL ++
Sbjct: 1552 EDAKLRLEVNL-QAMKAQFERDL---QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSM 1607
Query: 135 MKADRKRLKGEKTDL--------------VSQMQQLYATLESREEQLRDFIRNYEQ---H 177
A RK+L+ + DL + Q+++L A ++ +L D + E+
Sbjct: 1608 AVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQ 1667
Query: 178 RKESEDAVKA-------LAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKEL 230
KE+E +K+ L +E ER K + +++ E D + L + L
Sbjct: 1668 AKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRL 1727
Query: 231 EAELAMAKQSL 241
EA +A ++ L
Sbjct: 1728 EARIAQLEEEL 1738
Score = 35.4 bits (80), Expect = 0.096
Identities = 40/169 (23%), Positives = 74/169 (43%), Gaps = 25/169 (14%)
Query: 80 QEEVHLLRQMK-EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKAD 138
Q+E+ R+ + +L K LEE +++ E+R + +Q +ELA E + +KA+
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAKTHEAQI---QEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 139 RKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLERE 198
++ K TLE+ +L + ++ Q + +SE K + + L+ +
Sbjct: 1215 LEKAK--------------QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 199 KWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
E R E D T L+ +LD + L+ + + LTKD
Sbjct: 1261 FNEGERVRTELADKVTKLQVELD-------NVTGLLSQSDSKSSKLTKD 1302
Score = 34.7 bits (78), Expect = 0.16
Identities = 43/194 (22%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKE-QELARAKE 130
L ++V++LQ E L + +L++ +S+ K ++ SA E ++Q Q+ QE R K
Sbjct: 1271 LADKVTKLQVE---LDNVTGLLSQS--DSKSSKLTKDFSALESQLQDTQELLQEENRQKL 1325
Query: 131 ALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAK 190
+L K+++ EK Q+++ + E+Q+ +K+ ED+V L
Sbjct: 1326 SLSTKL---KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLET 1382
Query: 191 EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE---AELAMAKQSLATLTKD 247
+++ + + +L ++ + A K +EL+ +L +QS L K
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 248 VPKRHSLAMPGETV 261
K L +T+
Sbjct: 1443 QKKFDQLLAEEKTI 1456
Score = 32.7 bits (73), Expect = 0.62
Identities = 37/197 (18%), Positives = 84/197 (42%), Gaps = 23/197 (11%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 133
EE++ E+ ++ E + LE +G ++EV + + K +++ + LQ
Sbjct: 1199 EELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQ 1258
Query: 134 AMKADRKRLKGEKTDLVSQMQ---------------------QLYATLESREEQLRDFIR 172
+ +R++ E D V+++Q + ++ LES+ + ++ ++
Sbjct: 1259 VKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQ 1318
Query: 173 NYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATA-LRSQLDLKDNRMKELE 231
+ + +K + EK+ RE+ E +AK + A L +Q+ +M++
Sbjct: 1319 EENRQKLSLSTKLKQVEDEKNSF-REQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV 1377
Query: 232 AELAMAKQSLATLTKDV 248
L A++ L KD+
Sbjct: 1378 GCLETAEEVKRKLQKDL 1394
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 55.8 bits (133), Expect = 7e-08
Identities = 47/161 (29%), Positives = 73/161 (45%), Gaps = 17/161 (10%)
Query: 104 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 156
K +L + E ++A ++E R KEAL+ +A RK L+ EK DL Q+Q
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 894
Query: 157 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 206
L EE+ I+N Q R E E+ + A L +K LE E EL+R
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 207 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
+ + + +N++K L E+A + +A LTK+
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/209 (26%), Positives = 94/209 (44%), Gaps = 32/209 (15%)
Query: 54 RAGVPRVRAD-----GDCSQPVLLREEVSRLQEEVHLLRQMK-EMLAKDLEESQGGKSSE 107
RA V ++R+D + S+ + + +Q E++ R+ + + + +DLEE+
Sbjct: 1129 RAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT---LQH 1185
Query: 108 VLSATELRVQLAQKEQELARAKEALQAMKA----DRKRLKGEKTDLVSQMQQLY---ATL 160
+A LR + A EL + LQ +K ++ K E D+ S M+Q+ A L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 161 ESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQL 220
E L D + + +E++ +V L ++ L+ E EL RQ D AL SQL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQ----LDEKEALISQL 1301
Query: 221 ------------DLKDNRMKELEAELAMA 237
DLK +E++A+ A+A
Sbjct: 1302 TRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQA 134
+S+L Q E L + LEE K+ A +Q A+ + +L R + E
Sbjct: 1298 ISQLTRGKLTYTQQLEDLKRQLEEEVKAKN-----ALAHALQSARHDCDLLREQYEEETE 1352
Query: 135 MKADRKRLKGEKTDLVSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
KA+ +R+ + V+Q + Y T R E+L + + Q +E+E+AV+A+ +
Sbjct: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCS 1412
Query: 194 LLEREKWELRRQAKEA---TDHATALRSQLDLKDNRMKELEAE 233
LE+ K L+ + ++ + + A + LD K ++ AE
Sbjct: 1413 SLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 8/157 (5%)
Query: 98 EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 157
EESQ S A L +L + + + E L+ K + K L+ E +DL Q+
Sbjct: 1461 EESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSG 1520
Query: 158 ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL--------RRQAKEA 209
T+ E+ + + + E+A +L E+ + R + E R+ A++
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 210 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 246
+ A R+ L + D+ L+AE ++L K
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617
Score = 40.4 bits (93), Expect = 0.003
Identities = 47/204 (23%), Positives = 91/204 (44%), Gaps = 41/204 (20%)
Query: 65 DCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSAT-------ELRVQ 117
DC LLRE+ +EE +++ +L+K E ++ A E + +
Sbjct: 1339 DCD---LLREQY---EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1392
Query: 118 LAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDF--- 170
LAQ+ QE A EA+ A ++ + RL+ E DL+ +++ A + +++ R+F
Sbjct: 1393 LAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452
Query: 171 IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ--------LDL 222
+ ++Q +ES+ +++ KE L E ++L+ +E+ +H + + DL
Sbjct: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 223 KDNR-------------MKELEAE 233
+ K+LEAE
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAE 1536
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/171 (16%), Positives = 71/171 (41%), Gaps = 3/171 (1%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA 131
L E++ L +E + L+ + +L +++ + + +L ++ + + L +E
Sbjct: 873 LEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 932
Query: 132 LQAMKADRKRLKGEKTDLVSQMQQLYATL---ESREEQLRDFIRNYEQHRKESEDAVKAL 188
+ A +++L+ E ++L + L TL E + + ++N + ++ + L
Sbjct: 933 NAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 992
Query: 189 AKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 239
KEK L+ + + D L + ++ +LE L K+
Sbjct: 993 TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKK 1043
Score = 34.7 bits (78), Expect = 0.16
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 10/184 (5%)
Query: 61 RADGDCSQPVLLREEVSRLQEEVHLLRQMK-EMLAKDLE-ESQGGKSSEVLSATELRVQL 118
R D + L +V + E + +M E+ AK + E + + + EL +
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK 963
Query: 119 AQKEQELARAK-----EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 173
+KE+ K E + + +L EK L QQ L++ E+++ +
Sbjct: 964 VEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 174 YEQHRKESEDAVKALAKEKDL---LEREKWELRRQAKEATDHATALRSQLDLKDNRMKEL 230
+ ++ +D +L +EK + LER K +L K + L + D R+K+
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 231 EAEL 234
+ EL
Sbjct: 1084 DFEL 1087
Score = 32.3 bits (72), Expect = 0.81
Identities = 37/195 (18%), Positives = 86/195 (44%), Gaps = 14/195 (7%)
Query: 61 RADGDCSQPVLLREEVSRLQEEVHLLRQMKE-------MLAKDLEESQGGKSSEVLSATE 113
+ D D SQ L+ EV +E + + M+A++L++ Q +
Sbjct: 1729 KMDADLSQ---LQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1785
Query: 114 LRVQLAQKEQELARAKE-ALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 172
+ + + L A++ AL+ K ++L+ +L ++++ + +R R
Sbjct: 1786 MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSER 1845
Query: 173 NYEQHRKESEDAVKALAKEKDLLEREKWEL---RRQAKEATDHATALRSQLDLKDNRMKE 229
++ ++E+ K L + +DL+++ + ++ +RQA+EA + A S+ + + E
Sbjct: 1846 RIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 1905
Query: 230 LEAELAMAKQSLATL 244
E +A+ + L
Sbjct: 1906 AEERADIAESQVNKL 1920
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/254 (20%), Positives = 117/254 (46%), Gaps = 32/254 (12%)
Query: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQ----LAQKE 122
SQ L E+S L++++ + + L ++L+ ++ + T L + L +
Sbjct: 839 SQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQ 898
Query: 123 QELARAKEALQAMKADRKRLKGEKT------------DLVSQMQQLYATLESREEQLRDF 170
+E+A K+ L M+ ++T DLVSQ++Q + +E+L+
Sbjct: 899 KEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTS 958
Query: 171 IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQL--------DL 222
N EQ++ ++L KEK + E + + + KE+ + T L +L +L
Sbjct: 959 TSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQEL 1018
Query: 223 KDNR---MKELEAELAMAKQSLATLTKDVP---KRHSLAMPGETVLNGNQEWVVQADLPL 276
+D++ ++ +E +L+ K++L+++ +V +R S A+ E ++ QA + +
Sbjct: 1019 QDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQ--QARRDCQEQAKIAV 1076
Query: 277 TAAIRQSQQTLYHS 290
A + ++ + H+
Sbjct: 1077 EAQNKYERELMLHA 1090
Score = 51.2 bits (121), Expect = 2e-06
Identities = 67/288 (23%), Positives = 115/288 (39%), Gaps = 18/288 (6%)
Query: 81 EEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRK 140
+E H+ Q + L + L +++ S L+ L++KE E +E ++++
Sbjct: 1467 QEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELS 1526
Query: 141 RLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKW 200
RL+ + D +Q +QL + +EE+ R I + L KE + L++
Sbjct: 1527 RLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNG 1586
Query: 201 ELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE- 259
L +Q E TAL+SQ + R+ LE EL Q +D P+ S +P +
Sbjct: 1587 ALDQQKDELDVRITALKSQY---EGRISRLEREL-REHQERHLEQRDEPQEPSNKVPEQQ 1642
Query: 260 ------TVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSV 313
T + + P TA I+ + S A + +P S +P V
Sbjct: 1643 RQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSKVT-AAAMAGNKSTPRASIRPMV 1701
Query: 314 ISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQS 361
A + ++TP+ P + S S GPV+ H P+ S
Sbjct: 1702 ---TPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVE---HVPVFGS 1743
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/300 (20%), Positives = 125/300 (41%), Gaps = 18/300 (6%)
Query: 87 RQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEK 146
RQ E+L ++L+E Q ++E +AQ E EL + E + + K L+ EK
Sbjct: 1225 RQRVELLERELQELQDSLNAEREKVQVTAKTMAQHE-ELMKKTETMNVVMETNKMLREEK 1283
Query: 147 TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLERE--KWELR- 203
L +QQ+ A + E D + E + + SE + L EK LLE + +W+ R
Sbjct: 1284 ERLEQDLQQMQAKVRKLE---LDILPLQEANAELSEKS-GMLQAEKKLLEEDVKRWKARN 1339
Query: 204 -----RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPG 258
+Q T+ L S+ ++ R+++L E+ K +A + +L
Sbjct: 1340 QHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSL 1399
Query: 259 ETVLN--GNQEWVVQADLPLTAA-IRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVIS 315
+ LN ++ +Q DL I++ +T+ + R + ++Q V+
Sbjct: 1400 KEDLNKVRTEKETIQKDLDAKIIDIQEKVKTI--TQVKKIGRRYKTQYEELKAQQDKVME 1457
Query: 316 DASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKE 375
++ + GD + + +L ++ ++ + ++L + E + R +++
Sbjct: 1458 TSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQ 1517
Score = 45.8 bits (107), Expect = 7e-05
Identities = 42/206 (20%), Positives = 91/206 (44%), Gaps = 13/206 (6%)
Query: 56 GVPRVRADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGG-------KSSEV 108
G +++ D + V ++ RL++E LL L +L+ K +E+
Sbjct: 160 GELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEI 219
Query: 109 LSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 168
L EL+ L K++E++R +E + +K + L+ DL++++++ S EE+
Sbjct: 220 L---ELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH 276
Query: 169 DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK 228
+ + + + + A + + L R EL + KEA + A++ L +
Sbjct: 277 NELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKD 336
Query: 229 ELEAELAMAKQSLATLTKDVPKRHSL 254
++E E+ + + L K++ + L
Sbjct: 337 QMEKEML---EKIGRLEKELENANDL 359
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 12/176 (6%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSS---EVLSATELRVQLAQKEQELARAKE 130
E ++ + E +LR+ KE L +DL++ Q ++L E +L++K L K+
Sbjct: 1267 ETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKK 1326
Query: 131 ALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAK 190
L+ D KR K LVSQ + + E+ R + E H K + + + +
Sbjct: 1327 LLE---EDVKRWKARNQHLVSQQK------DPDTEEYRKLLSEKEVHTKRIQQLTEEIGR 1377
Query: 191 EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 246
K + R L L K+ K+L+A++ ++ + T+T+
Sbjct: 1378 LKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQ 1433
Score = 37.0 bits (84), Expect = 0.033
Identities = 31/157 (19%), Positives = 66/157 (42%), Gaps = 3/157 (1%)
Query: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELA 126
SQ L++ +S + E L++ L +L + +LR Q+ +KE+
Sbjct: 1495 SQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEE--- 1551
Query: 127 RAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVK 186
+ ++A+ A K+ L G K L + ++L + ++Q + + + E +
Sbjct: 1552 KTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRIS 1611
Query: 187 ALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLK 223
L +E + E R + +E ++ + Q+ LK
Sbjct: 1612 RLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLK 1648
Score = 35.0 bits (79), Expect = 0.13
Identities = 41/194 (21%), Positives = 80/194 (41%), Gaps = 22/194 (11%)
Query: 73 REEVSRLQEEVHLLR---QMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
R E++ L E L Q +E + + + G ++E L+ E+R + +KE+E+ +
Sbjct: 736 RREITSLHERNQKLTATTQKQEQIINTMTQDLRG-ANEKLAVAEVRAENLKKEKEMLKLS 794
Query: 130 EALQAMKADRKRLKGEKTD---LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVK 186
E + R+ L E+ L++ +Q + LE E + + ++ + E
Sbjct: 795 EV--RLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETK------QRLSSQIEKLEH 846
Query: 187 ALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN-------RMKELEAELAMAKQ 239
++ K LE E + + + QLD + N +K + E+A KQ
Sbjct: 847 EISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQ 906
Query: 240 SLATLTKDVPKRHS 253
L+ + V + S
Sbjct: 907 HLSNMEVQVASQSS 920
Score = 33.9 bits (76), Expect = 0.28
Identities = 36/177 (20%), Positives = 78/177 (44%), Gaps = 33/177 (18%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM 135
V+ L+E ++ +Q+ E + K++E + + E + QL +K E+ + K+ LQ
Sbjct: 969 VTSLEESLNKEKQVTEEVRKNIEV-------RLKESAEFQTQLEKKLMEVEKEKQELQD- 1020
Query: 136 KADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 195
D++R +ES E+QL + + + E ++A++ +
Sbjct: 1021 --DKRR-----------------AIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061
Query: 196 EREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA------ELAMAKQSLATLTK 246
++ + + + QAK A + +L L ++ L+A ++A +Q L T+
Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQ 1118
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 53.9 bits (128), Expect = 3e-07
Identities = 40/171 (23%), Positives = 88/171 (51%), Gaps = 9/171 (5%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMK 136
++++ + + RQ +EM AK+ +E Q K + + EL+ +L QK +L K LQ
Sbjct: 839 TKVKPLLQVTRQEEEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ--- 893
Query: 137 ADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLE 196
++L+ E T+L ++ +++ L +++++L + + E +E ED + L E+ +
Sbjct: 894 ---EQLQAE-TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 949
Query: 197 REKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
++ +L Q +E L+ + + ++K+LE E+ + L+K+
Sbjct: 950 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/202 (25%), Positives = 91/202 (45%), Gaps = 24/202 (11%)
Query: 55 AGVPRVRADGDCSQPVLLREEVSRL------QEEVHLLRQMKEMLAKDLEESQG---GKS 105
A R R D + L E S L Q+E L L ++LEE QG S
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 106 SEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESR-- 163
V AT+ Q Q ELA + Q ++ R++L+ + +L S++ ++ ++S+
Sbjct: 1757 DRVRKATQ---QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1813
Query: 164 ------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 217
E ++ EQ +E + A K+L K+KD ++ E+ Q ++ A +
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSL-KQKD---KKLKEILLQVEDERKMAEQYK 1869
Query: 218 SQLDLKDNRMKELEAELAMAKQ 239
Q + + R+K+L+ +L A++
Sbjct: 1870 EQAEKGNARVKQLKRQLEEAEE 1891
Score = 51.6 bits (122), Expect = 1e-06
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKD---LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
+E + + E+ L Q L ++ L+E ++ A E+RV+LA K+QEL
Sbjct: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 924
Query: 130 EALQA-----------MKADRKRLKGEKTDLVSQMQQLYAT---LESREEQLRDFIRNYE 175
++A ++A+RK++ + DL Q+++ A L+ + I+ E
Sbjct: 925 HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
+D L+KE+ LLE +L E + A L + ++ + ELE L
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 236 MAKQSLATLTK 246
++S L K
Sbjct: 1045 KEEKSRQELEK 1055
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/190 (21%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM 135
+S L+ + + ++ L K + +G S +L+ Q+A+ + +LA+ +E LQA
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 136 KA--------------DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKES 181
A + L+G +DL + A E+Q RD E + E
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 182 EDAVKALAKEKDLLEREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMA 237
ED + + A +++L + + E+ + +E H ++ ++EL +L
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1215
Query: 238 KQSLATLTKD 247
K++ A L K+
Sbjct: 1216 KRAKANLDKN 1225
Score = 43.9 bits (102), Expect = 3e-04
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 28/198 (14%)
Query: 71 LLREEVSRLQEEVHLLRQMKE---MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
LL+EE + LRQ++E L L+E K + + L +QL+ +++L
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESRE-------EQLRDFIRNYEQHR-- 178
++A++ +KR + E +L Q ++ A + E ++L D + + + R
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQL 1442
Query: 179 -----KESEDAVKALAKEK-------DLLEREKWELRRQAKEATDHATALRSQLDLKDNR 226
K+ + LA+EK D +R + E R + +A A AL L+ K+
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE-- 1500
Query: 227 MKELEAELAMAKQSLATL 244
ELE M K + L
Sbjct: 1501 --ELERTNKMLKAEMEDL 1516
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/179 (24%), Positives = 77/179 (43%), Gaps = 19/179 (10%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE--------LRVQLAQKEQ 123
++ ++ L++E+ K L +++ +G ++ + E L+ QL + E
Sbjct: 1544 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1603
Query: 124 ELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREEQLRDFIRNYEQ 176
EL ++ A +K+L+G+ DL + ++ L + Q++DF R E
Sbjct: 1604 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663
Query: 177 HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
R S D + A AKE + + Q +E A R Q DL+ +EL ELA
Sbjct: 1664 AR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE---KEELAEELA 1718
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAM 135
++ QE +L +M+ L ++ + Q ++ A + L ++ +E+E AR K L+ +
Sbjct: 915 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 974
Query: 136 KADRKRLKGEKTDLVSQMQQLYATLESR--EEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
A+ K K E LV Q + E + EE++ D N + +++++ K K +
Sbjct: 975 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034
Query: 194 LLEREKWELRRQAKEATDHATALRS-QLDLKD--NRMKELEAELAMAKQSLA 242
++ + L+++ K + R + D D ++ +L+A++A K LA
Sbjct: 1035 MISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 84/180 (46%), Gaps = 16/180 (8%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAK 129
E+ ++E+ + E AK LE ++ +A R Q +KE+ ELA +
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 130 EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
A++ +++RL+ L ++++ +E+ +++R + EQ +E A +
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERST 1779
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 248
+K+ E + +L RQ KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1780 AQKN--ESARQQLERQNKE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830
Score = 36.2 bits (82), Expect = 0.056
Identities = 40/176 (22%), Positives = 83/176 (47%), Gaps = 8/176 (4%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEAL 132
R +++QE Q E L + LE+ + K++ + L + A EL +A
Sbjct: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1247
Query: 133 QAMKADRKRLKGEKTDLVSQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
Q ++ +K+L+ + +L S+ ++ A L + +L++ + + E+E LA
Sbjct: 1248 QEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1307
Query: 190 KEKDLLEREKWE----LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
K+ L + + L+ + ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1308 KDVASLSSQLQDTQELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1362
Score = 33.9 bits (76), Expect = 0.28
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 34/205 (16%)
Query: 71 LLREEVSRLQEEVHLLRQM---KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
+L E +RL+EE +Q+ ++ +A+ + + + E + +L+++ E ++ +
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE-SEDAVK 186
++ + M +L E+ L ++ L L EE+ ++ + +H SE V+
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 187 ALAKEKDLLEREKW-----------------------ELRRQAKEATDHATALRSQLD-- 221
+EK E EK EL+ Q + + A ++LD
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 222 --LKDNRMK---ELEAELAMAKQSL 241
K+N +K ELE ++ ++ L
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDL 1127
Score = 30.8 bits (68), Expect = 2.4
Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 32/202 (15%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSA--TELRVQL--AQKEQELAR 127
L +S LQE++ E A++ E Q E L A TEL L +QEL
Sbjct: 1116 LEGHISDLQEDLD-----SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA 1170
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHR--------- 178
+E Q + +K L E +Q+Q++ E+L + + +++ +
Sbjct: 1171 KRE--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1228
Query: 179 --KESED---AVKALAKEKDLLEREKWELRRQAKEATDHAT-ALRSQLDLKD------NR 226
KE+ D ++ L + K +E +K +L Q +E + R++ +L D N
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1288
Query: 227 MKELEAELAMAKQSLATLTKDV 248
++ + L A+ L KDV
Sbjct: 1289 VESVTGMLNEAEGKAIKLAKDV 1310
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 53.9 bits (128), Expect = 3e-07
Identities = 40/171 (23%), Positives = 88/171 (51%), Gaps = 9/171 (5%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMK 136
++++ + + RQ +EM AK+ +E Q K + + EL+ +L QK +L K LQ
Sbjct: 846 TKVKPLLQVTRQEEEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ--- 900
Query: 137 ADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLE 196
++L+ E T+L ++ +++ L +++++L + + E +E ED + L E+ +
Sbjct: 901 ---EQLQAE-TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 956
Query: 197 REKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
++ +L Q +E L+ + + ++K+LE E+ + L+K+
Sbjct: 957 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/202 (25%), Positives = 91/202 (45%), Gaps = 24/202 (11%)
Query: 55 AGVPRVRADGDCSQPVLLREEVSRL------QEEVHLLRQMKEMLAKDLEESQG---GKS 105
A R R D + L E S L Q+E L L ++LEE QG S
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 106 SEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESR-- 163
V AT+ Q Q ELA + Q ++ R++L+ + +L S++ ++ ++S+
Sbjct: 1764 DRVRKATQ---QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820
Query: 164 ------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 217
E ++ EQ +E + A K+L K+KD ++ E+ Q ++ A +
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSL-KQKD---KKLKEILLQVEDERKMAEQYK 1876
Query: 218 SQLDLKDNRMKELEAELAMAKQ 239
Q + + R+K+L+ +L A++
Sbjct: 1877 EQAEKGNARVKQLKRQLEEAEE 1898
Score = 51.6 bits (122), Expect = 1e-06
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKD---LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
+E + + E+ L Q L ++ L+E ++ A E+RV+LA K+QEL
Sbjct: 872 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 931
Query: 130 EALQA-----------MKADRKRLKGEKTDLVSQMQQLYAT---LESREEQLRDFIRNYE 175
++A ++A+RK++ + DL Q+++ A L+ + I+ E
Sbjct: 932 HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
+D L+KE+ LLE +L E + A L + ++ + ELE L
Sbjct: 992 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1051
Query: 236 MAKQSLATLTK 246
++S L K
Sbjct: 1052 KEEKSRQELEK 1062
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/190 (21%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM 135
+S L+ + + ++ L K + +G S +L+ Q+A+ + +LA+ +E LQA
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 136 KA--------------DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKES 181
A + L+G +DL + A E+Q RD E + E
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 182 EDAVKALAKEKDLLEREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMA 237
ED + + A +++L + + E+ + +E H ++ ++EL +L
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1222
Query: 238 KQSLATLTKD 247
K++ A L K+
Sbjct: 1223 KRAKANLDKN 1232
Score = 43.9 bits (102), Expect = 3e-04
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 28/198 (14%)
Query: 71 LLREEVSRLQEEVHLLRQMKE---MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
LL+EE + LRQ++E L L+E K + + L +QL+ +++L
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESRE-------EQLRDFIRNYEQHR-- 178
++A++ +KR + E +L Q ++ A + E ++L D + + + R
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQL 1449
Query: 179 -----KESEDAVKALAKEK-------DLLEREKWELRRQAKEATDHATALRSQLDLKDNR 226
K+ + LA+EK D +R + E R + +A A AL L+ K+
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE-- 1507
Query: 227 MKELEAELAMAKQSLATL 244
ELE M K + L
Sbjct: 1508 --ELERTNKMLKAEMEDL 1523
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/179 (24%), Positives = 77/179 (43%), Gaps = 19/179 (10%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE--------LRVQLAQKEQ 123
++ ++ L++E+ K L +++ +G ++ + E L+ QL + E
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1610
Query: 124 ELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREEQLRDFIRNYEQ 176
EL ++ A +K+L+G+ DL + ++ L + Q++DF R E
Sbjct: 1611 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Query: 177 HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
R S D + A AKE + + Q +E A R Q DL+ +EL ELA
Sbjct: 1671 AR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE---KEELAEELA 1725
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAM 135
++ QE +L +M+ L ++ + Q ++ A + L ++ +E+E AR K L+ +
Sbjct: 922 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 981
Query: 136 KADRKRLKGEKTDLVSQMQQLYATLESR--EEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
A+ K K E LV Q + E + EE++ D N + +++++ K K +
Sbjct: 982 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1041
Query: 194 LLEREKWELRRQAKEATDHATALRS-QLDLKD--NRMKELEAELAMAKQSLA 242
++ + L+++ K + R + D D ++ +L+A++A K LA
Sbjct: 1042 MISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 84/180 (46%), Gaps = 16/180 (8%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAK 129
E+ ++E+ + E AK LE ++ +A R Q +KE+ ELA +
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 130 EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
A++ +++RL+ L ++++ +E+ +++R + EQ +E A +
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERST 1786
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 248
+K+ E + +L RQ KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1787 AQKN--ESARQQLERQNKE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837
Score = 36.2 bits (82), Expect = 0.056
Identities = 40/176 (22%), Positives = 83/176 (47%), Gaps = 8/176 (4%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEAL 132
R +++QE Q E L + LE+ + K++ + L + A EL +A
Sbjct: 1195 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1254
Query: 133 QAMKADRKRLKGEKTDLVSQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
Q ++ +K+L+ + +L S+ ++ A L + +L++ + + E+E LA
Sbjct: 1255 QEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1314
Query: 190 KEKDLLEREKWE----LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
K+ L + + L+ + ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1315 KDVASLSSQLQDTQELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1369
Score = 33.9 bits (76), Expect = 0.28
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 34/205 (16%)
Query: 71 LLREEVSRLQEEVHLLRQM---KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
+L E +RL+EE +Q+ ++ +A+ + + + E + +L+++ E ++ +
Sbjct: 930 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE-SEDAVK 186
++ + M +L E+ L ++ L L EE+ ++ + +H SE V+
Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049
Query: 187 ALAKEKDLLEREKW-----------------------ELRRQAKEATDHATALRSQLD-- 221
+EK E EK EL+ Q + + A ++LD
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 222 --LKDNRMK---ELEAELAMAKQSL 241
K+N +K ELE ++ ++ L
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDL 1134
Score = 30.8 bits (68), Expect = 2.4
Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 32/202 (15%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSA--TELRVQL--AQKEQELAR 127
L +S LQE++ E A++ E Q E L A TEL L +QEL
Sbjct: 1123 LEGHISDLQEDLD-----SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA 1177
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHR--------- 178
+E Q + +K L E +Q+Q++ E+L + + +++ +
Sbjct: 1178 KRE--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1235
Query: 179 --KESED---AVKALAKEKDLLEREKWELRRQAKEATDHAT-ALRSQLDLKD------NR 226
KE+ D ++ L + K +E +K +L Q +E + R++ +L D N
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1295
Query: 227 MKELEAELAMAKQSLATLTKDV 248
++ + L A+ L KDV
Sbjct: 1296 VESVTGMLNEAEGKAIKLAKDV 1317
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 53.9 bits (128), Expect = 3e-07
Identities = 40/171 (23%), Positives = 88/171 (51%), Gaps = 9/171 (5%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMK 136
++++ + + RQ +EM AK+ +E Q K + + EL+ +L QK +L K LQ
Sbjct: 846 TKVKPLLQVTRQEEEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ--- 900
Query: 137 ADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLE 196
++L+ E T+L ++ +++ L +++++L + + E +E ED + L E+ +
Sbjct: 901 ---EQLQAE-TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 956
Query: 197 REKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
++ +L Q +E L+ + + ++K+LE E+ + L+K+
Sbjct: 957 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/202 (25%), Positives = 91/202 (45%), Gaps = 24/202 (11%)
Query: 55 AGVPRVRADGDCSQPVLLREEVSRL------QEEVHLLRQMKEMLAKDLEESQG---GKS 105
A R R D + L E S L Q+E L L ++LEE QG S
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 106 SEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESR-- 163
V AT+ Q Q ELA + Q ++ R++L+ + +L S++ ++ ++S+
Sbjct: 1764 DRVRKATQ---QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820
Query: 164 ------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 217
E ++ EQ +E + A K+L K+KD ++ E+ Q ++ A +
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSL-KQKD---KKLKEILLQVEDERKMAEQYK 1876
Query: 218 SQLDLKDNRMKELEAELAMAKQ 239
Q + + R+K+L+ +L A++
Sbjct: 1877 EQAEKGNARVKQLKRQLEEAEE 1898
Score = 51.6 bits (122), Expect = 1e-06
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKD---LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
+E + + E+ L Q L ++ L+E ++ A E+RV+LA K+QEL
Sbjct: 872 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 931
Query: 130 EALQA-----------MKADRKRLKGEKTDLVSQMQQLYAT---LESREEQLRDFIRNYE 175
++A ++A+RK++ + DL Q+++ A L+ + I+ E
Sbjct: 932 HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
+D L+KE+ LLE +L E + A L + ++ + ELE L
Sbjct: 992 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1051
Query: 236 MAKQSLATLTK 246
++S L K
Sbjct: 1052 KEEKSRQELEK 1062
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/190 (21%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM 135
+S L+ + + ++ L K + +G S +L+ Q+A+ + +LA+ +E LQA
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 136 KA--------------DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKES 181
A + L+G +DL + A E+Q RD E + E
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 182 EDAVKALAKEKDLLEREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMA 237
ED + + A +++L + + E+ + +E H ++ ++EL +L
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1222
Query: 238 KQSLATLTKD 247
K++ A L K+
Sbjct: 1223 KRAKANLDKN 1232
Score = 43.9 bits (102), Expect = 3e-04
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 28/198 (14%)
Query: 71 LLREEVSRLQEEVHLLRQMKE---MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
LL+EE + LRQ++E L L+E K + + L +QL+ +++L
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESRE-------EQLRDFIRNYEQHR-- 178
++A++ +KR + E +L Q ++ A + E ++L D + + + R
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQL 1449
Query: 179 -----KESEDAVKALAKEK-------DLLEREKWELRRQAKEATDHATALRSQLDLKDNR 226
K+ + LA+EK D +R + E R + +A A AL L+ K+
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE-- 1507
Query: 227 MKELEAELAMAKQSLATL 244
ELE M K + L
Sbjct: 1508 --ELERTNKMLKAEMEDL 1523
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/179 (24%), Positives = 77/179 (43%), Gaps = 19/179 (10%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE--------LRVQLAQKEQ 123
++ ++ L++E+ K L +++ +G ++ + E L+ QL + E
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1610
Query: 124 ELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREEQLRDFIRNYEQ 176
EL ++ A +K+L+G+ DL + ++ L + Q++DF R E
Sbjct: 1611 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Query: 177 HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
R S D + A AKE + + Q +E A R Q DL+ +EL ELA
Sbjct: 1671 AR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE---KEELAEELA 1725
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAM 135
++ QE +L +M+ L ++ + Q ++ A + L ++ +E+E AR K L+ +
Sbjct: 922 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 981
Query: 136 KADRKRLKGEKTDLVSQMQQLYATLESR--EEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
A+ K K E LV Q + E + EE++ D N + +++++ K K +
Sbjct: 982 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1041
Query: 194 LLEREKWELRRQAKEATDHATALRS-QLDLKD--NRMKELEAELAMAKQSLA 242
++ + L+++ K + R + D D ++ +L+A++A K LA
Sbjct: 1042 MISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 84/180 (46%), Gaps = 16/180 (8%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAK 129
E+ ++E+ + E AK LE ++ +A R Q +KE+ ELA +
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1728
Query: 130 EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
A++ +++RL+ L ++++ +E+ +++R + EQ +E A +
Sbjct: 1729 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERST 1786
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 248
+K+ E + +L RQ KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1787 AQKN--ESARQQLERQNKE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837
Score = 36.2 bits (82), Expect = 0.056
Identities = 40/176 (22%), Positives = 83/176 (47%), Gaps = 8/176 (4%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEAL 132
R +++QE Q E L + LE+ + K++ + L + A EL +A
Sbjct: 1195 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1254
Query: 133 QAMKADRKRLKGEKTDLVSQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
Q ++ +K+L+ + +L S+ ++ A L + +L++ + + E+E LA
Sbjct: 1255 QEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1314
Query: 190 KEKDLLEREKWE----LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
K+ L + + L+ + ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1315 KDVASLSSQLQDTQELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1369
Score = 33.9 bits (76), Expect = 0.28
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 34/205 (16%)
Query: 71 LLREEVSRLQEEVHLLRQM---KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
+L E +RL+EE +Q+ ++ +A+ + + + E + +L+++ E ++ +
Sbjct: 930 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE-SEDAVK 186
++ + M +L E+ L ++ L L EE+ ++ + +H SE V+
Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049
Query: 187 ALAKEKDLLEREKW-----------------------ELRRQAKEATDHATALRSQLD-- 221
+EK E EK EL+ Q + + A ++LD
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Query: 222 --LKDNRMK---ELEAELAMAKQSL 241
K+N +K ELE ++ ++ L
Sbjct: 1110 IAQKNNALKKIRELEGHISDLQEDL 1134
Score = 30.8 bits (68), Expect = 2.4
Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 32/202 (15%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSA--TELRVQL--AQKEQELAR 127
L +S LQE++ E A++ E Q E L A TEL L +QEL
Sbjct: 1123 LEGHISDLQEDLD-----SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA 1177
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHR--------- 178
+E Q + +K L E +Q+Q++ E+L + + +++ +
Sbjct: 1178 KRE--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1235
Query: 179 --KESED---AVKALAKEKDLLEREKWELRRQAKEATDHAT-ALRSQLDLKD------NR 226
KE+ D ++ L + K +E +K +L Q +E + R++ +L D N
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1295
Query: 227 MKELEAELAMAKQSLATLTKDV 248
++ + L A+ L KDV
Sbjct: 1296 VESVTGMLNEAEGKAIKLAKDV 1317
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 53.9 bits (128), Expect = 3e-07
Identities = 40/171 (23%), Positives = 88/171 (51%), Gaps = 9/171 (5%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMK 136
++++ + + RQ +EM AK+ +E Q K + + EL+ +L QK +L K LQ
Sbjct: 839 TKVKPLLQVTRQEEEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ--- 893
Query: 137 ADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLE 196
++L+ E T+L ++ +++ L +++++L + + E +E ED + L E+ +
Sbjct: 894 ---EQLQAE-TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 949
Query: 197 REKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
++ +L Q +E L+ + + ++K+LE E+ + L+K+
Sbjct: 950 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/202 (25%), Positives = 91/202 (45%), Gaps = 24/202 (11%)
Query: 55 AGVPRVRADGDCSQPVLLREEVSRL------QEEVHLLRQMKEMLAKDLEESQG---GKS 105
A R R D + L E S L Q+E L L ++LEE QG S
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 106 SEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESR-- 163
V AT+ Q Q ELA + Q ++ R++L+ + +L S++ ++ ++S+
Sbjct: 1757 DRVRKATQ---QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1813
Query: 164 ------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 217
E ++ EQ +E + A K+L K+KD ++ E+ Q ++ A +
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSL-KQKD---KKLKEILLQVEDERKMAEQYK 1869
Query: 218 SQLDLKDNRMKELEAELAMAKQ 239
Q + + R+K+L+ +L A++
Sbjct: 1870 EQAEKGNARVKQLKRQLEEAEE 1891
Score = 51.6 bits (122), Expect = 1e-06
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKD---LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
+E + + E+ L Q L ++ L+E ++ A E+RV+LA K+QEL
Sbjct: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 924
Query: 130 EALQA-----------MKADRKRLKGEKTDLVSQMQQLYAT---LESREEQLRDFIRNYE 175
++A ++A+RK++ + DL Q+++ A L+ + I+ E
Sbjct: 925 HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
+D L+KE+ LLE +L E + A L + ++ + ELE L
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 236 MAKQSLATLTK 246
++S L K
Sbjct: 1045 KEEKSRQELEK 1055
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/190 (21%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 76 VSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM 135
+S L+ + + ++ L K + +G S +L+ Q+A+ + +LA+ +E LQA
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 136 KA--------------DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKES 181
A + L+G +DL + A E+Q RD E + E
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 182 EDAVKALAKEKDLLEREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMA 237
ED + + A +++L + + E+ + +E H ++ ++EL +L
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1215
Query: 238 KQSLATLTKD 247
K++ A L K+
Sbjct: 1216 KRAKANLDKN 1225
Score = 43.9 bits (102), Expect = 3e-04
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 28/198 (14%)
Query: 71 LLREEVSRLQEEVHLLRQMKE---MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
LL+EE + LRQ++E L L+E K + + L +QL+ +++L
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESRE-------EQLRDFIRNYEQHR-- 178
++A++ +KR + E +L Q ++ A + E ++L D + + + R
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQL 1442
Query: 179 -----KESEDAVKALAKEK-------DLLEREKWELRRQAKEATDHATALRSQLDLKDNR 226
K+ + LA+EK D +R + E R + +A A AL L+ K+
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE-- 1500
Query: 227 MKELEAELAMAKQSLATL 244
ELE M K + L
Sbjct: 1501 --ELERTNKMLKAEMEDL 1516
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/179 (24%), Positives = 77/179 (43%), Gaps = 19/179 (10%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE--------LRVQLAQKEQ 123
++ ++ L++E+ K L +++ +G ++ + E L+ QL + E
Sbjct: 1544 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1603
Query: 124 ELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREEQLRDFIRNYEQ 176
EL ++ A +K+L+G+ DL + ++ L + Q++DF R E
Sbjct: 1604 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663
Query: 177 HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
R S D + A AKE + + Q +E A R Q DL+ +EL ELA
Sbjct: 1664 AR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE---KEELAEELA 1718
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAM 135
++ QE +L +M+ L ++ + Q ++ A + L ++ +E+E AR K L+ +
Sbjct: 915 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 974
Query: 136 KADRKRLKGEKTDLVSQMQQLYATLESR--EEQLRDFIRNYEQHRKESEDAVKALAKEKD 193
A+ K K E LV Q + E + EE++ D N + +++++ K K +
Sbjct: 975 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034
Query: 194 LLEREKWELRRQAKEATDHATALRS-QLDLKD--NRMKELEAELAMAKQSLA 242
++ + L+++ K + R + D D ++ +L+A++A K LA
Sbjct: 1035 MISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/180 (22%), Positives = 84/180 (46%), Gaps = 16/180 (8%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAK 129
E+ ++E+ + E AK LE ++ +A R Q +KE+ ELA +
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL 1721
Query: 130 EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
A++ +++RL+ L ++++ +E+ +++R + EQ +E A +
Sbjct: 1722 SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERST 1779
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 248
+K+ E + +L RQ KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1780 AQKN--ESARQQLERQNKE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830
Score = 36.2 bits (82), Expect = 0.056
Identities = 40/176 (22%), Positives = 83/176 (47%), Gaps = 8/176 (4%)
Query: 73 REEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEAL 132
R +++QE Q E L + LE+ + K++ + L + A EL +A
Sbjct: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1247
Query: 133 QAMKADRKRLKGEKTDLVSQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
Q ++ +K+L+ + +L S+ ++ A L + +L++ + + E+E LA
Sbjct: 1248 QEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1307
Query: 190 KEKDLLEREKWE----LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
K+ L + + L+ + ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1308 KDVASLSSQLQDTQELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1362
Score = 33.9 bits (76), Expect = 0.28
Identities = 41/205 (20%), Positives = 86/205 (41%), Gaps = 34/205 (16%)
Query: 71 LLREEVSRLQEEVHLLRQM---KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELAR 127
+L E +RL+EE +Q+ ++ +A+ + + + E + +L+++ E ++ +
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKE-SEDAVK 186
++ + M +L E+ L ++ L L EE+ ++ + +H SE V+
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 187 ALAKEKDLLEREKW-----------------------ELRRQAKEATDHATALRSQLD-- 221
+EK E EK EL+ Q + + A ++LD
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 222 --LKDNRMK---ELEAELAMAKQSL 241
K+N +K ELE ++ ++ L
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDL 1127
Score = 30.8 bits (68), Expect = 2.4
Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 32/202 (15%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSA--TELRVQL--AQKEQELAR 127
L +S LQE++ E A++ E Q E L A TEL L +QEL
Sbjct: 1116 LEGHISDLQEDLD-----SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA 1170
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHR--------- 178
+E Q + +K L E +Q+Q++ E+L + + +++ +
Sbjct: 1171 KRE--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1228
Query: 179 --KESED---AVKALAKEKDLLEREKWELRRQAKEATDHAT-ALRSQLDLKD------NR 226
KE+ D ++ L + K +E +K +L Q +E + R++ +L D N
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1288
Query: 227 MKELEAELAMAKQSLATLTKDV 248
++ + L A+ L KDV
Sbjct: 1289 VESVTGMLNEAEGKAIKLAKDV 1310
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 53.5 bits (127), Expect = 3e-07
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 17/161 (10%)
Query: 104 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 156
K +L + E ++A ++E R KE L+ +A RK L+ EK DL Q+Q
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 896
Query: 157 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 206
L EE+ I+N Q R E E+ + A L +K LE E EL++
Sbjct: 897 QDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
Query: 207 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
+ + + +N++K L E+A + +A LTK+
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 997
Score = 42.7 bits (99), Expect = 6e-04
Identities = 64/300 (21%), Positives = 123/300 (41%), Gaps = 24/300 (8%)
Query: 54 RAGVPRVRAD-----GDCSQPVLLREEVSRLQEEVHLLRQMK-EMLAKDLEESQGGKSSE 107
RA V ++R+D + S+ + + +Q E++ R+ + + + +DLEE+
Sbjct: 1131 RAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEAT---LQH 1187
Query: 108 VLSATELRVQLAQKEQELARAKEALQAMKA----DRKRLKGEKTDLVSQMQQLY---ATL 160
+A LR + A EL + LQ +K ++ K E D+ S M+Q+ A L
Sbjct: 1188 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1247
Query: 161 ESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQL 220
E L D Y +E++ ++ ++ L+ E EL RQ +E + L
Sbjct: 1248 EKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGK 1307
Query: 221 DLKDNRMKELEAEL---AMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLT 277
+M++L+ +L AK +LA + RH + E +E +A+L
Sbjct: 1308 LSYTQQMEDLKRQLEEEGKAKNALAHALQSA--RHDCDLLREQY---EEETEAKAELQRV 1362
Query: 278 AAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHR 337
+ S+ + + A ++ + + + DA A ++ S + +HR
Sbjct: 1363 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHR 1422
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/151 (25%), Positives = 73/151 (48%), Gaps = 10/151 (6%)
Query: 88 QMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEK 146
Q E L + LEE GK+ L+ +Q A+ + +L R + E KA+ +R+ +
Sbjct: 1312 QQMEDLKRQLEEE--GKAKNALAHA---LQSARHDCDLLREQYEEETEAKAELQRVLSKA 1366
Query: 147 TDLVSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQ 205
V+Q + Y T R E+L + + Q +++E+AV+A+ + LE+ K L+ +
Sbjct: 1367 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNE 1426
Query: 206 AKEA---TDHATALRSQLDLKDNRMKELEAE 233
++ + + A + LD K ++ AE
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAE 1457
Score = 36.2 bits (82), Expect = 0.056
Identities = 29/171 (16%), Positives = 72/171 (42%), Gaps = 3/171 (1%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA 131
L E++ L +E + L+ + +L +++ + + +L ++ + + L +E
Sbjct: 875 LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 934
Query: 132 LQAMKADRKRLKGEKTDLVSQMQQLYATL---ESREEQLRDFIRNYEQHRKESEDAVKAL 188
+ A +++L+ E ++L + L TL E + + ++N + ++ + L
Sbjct: 935 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 994
Query: 189 AKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 239
KEK L+ + + D +L + ++ +LE L K+
Sbjct: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKK 1045
Score = 33.1 bits (74), Expect = 0.48
Identities = 41/204 (20%), Positives = 89/204 (43%), Gaps = 41/204 (20%)
Query: 65 DCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQE 124
DC LLRE+ +EE +++ +L+K E ++ A + +L + +++
Sbjct: 1341 DCD---LLREQY---EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1394
Query: 125 LAR----AKEALQAMKAD-------RKRLKGEKTDLVSQMQQLYATLESREEQLRDF--- 170
LA+ A+EA++A+ A + RL+ E DL+ +++ A + +++ R+F
Sbjct: 1395 LAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1454
Query: 171 IRNYEQHRKESEDAVKALAKEK---------------------DLLEREKWELRRQAKEA 209
+ ++Q +ES+ +++ KE + +RE L+ + +
Sbjct: 1455 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1514
Query: 210 TDHATALRSQLDLKDNRMKELEAE 233
T+ + + K+LE E
Sbjct: 1515 TEQLGEGGKNVHELEKVRKQLEVE 1538
Score = 32.7 bits (73), Expect = 0.62
Identities = 35/183 (19%), Positives = 87/183 (47%), Gaps = 16/183 (8%)
Query: 77 SRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM- 135
S ++E V R +E K + ++ + E+ + L + ++ + + + LQ
Sbjct: 1741 SEVEEAVQECRNAEEKAKKAITDA-AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1799
Query: 136 -KADRKRLKGEKTDLV---SQMQQLYATLESREEQLRDFIRNYEQHRK-------ESEDA 184
+A++ LKG K L +++++L LE+ +++ + ++ + + ++E+
Sbjct: 1800 DEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEED 1859
Query: 185 VKALAKEKDLLEREKWEL---RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
K L + +DL+++ + ++ +RQA+EA + A S+ + + E E +A+ +
Sbjct: 1860 KKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV 1919
Query: 242 ATL 244
L
Sbjct: 1920 NKL 1922
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 53.5 bits (127), Expect = 3e-07
Identities = 58/214 (27%), Positives = 97/214 (45%), Gaps = 28/214 (13%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSAT-------ELRVQLAQKEQE 124
L E++SRLQ E + ++ E +D+ E + V A+ +L+ QL + +E
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1789
Query: 125 LARAKEALQAMKADRKRLKGEKTD--LVSQMQQLYATLESREEQLRDFIRNYEQHRKESE 182
+E LQA+++ + L+ D LVS+ + LE+R E R ++ E +
Sbjct: 1790 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLK 1849
Query: 183 DAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLA 242
+ ++ L +E+D +R A E + R Q L+D KE ELA + +
Sbjct: 1850 ENMEKLTEERD---------QRIAAENREKEQNKRLQRQLRDT--KEEMGELARKEAEAS 1898
Query: 243 TLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPL 276
K+H L M E++ NQ +QADL L
Sbjct: 1899 R------KKHELEMDLESLEAANQS--LQADLKL 1924
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/178 (24%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKD----LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
+E+ EEV RQ + K LEE K + EL +LA ++ R
Sbjct: 1588 KEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRD 1647
Query: 130 -EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKAL 188
E+ + ++ D KR K D + L + S+ E I + +ESE A
Sbjct: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-----IAQLKNQLEESEFTCAAA 1702
Query: 189 AKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 246
K + +E E +L Q + TAL QL E++ L ++ + L K
Sbjct: 1703 VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1760
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 28/211 (13%)
Query: 73 REEVSR--LQEEVHLLRQMKEMLAKDLEESQ---GGKSSEVLS----ATELRVQLAQKEQ 123
RE++ R LQ E +L L + LEE G + +V+S ++ Q ++ E
Sbjct: 1476 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEA 1535
Query: 124 ELARAKEALQAMKA---DRKRLKGEKTDLVSQMQQLYATLESREEQLRD-FIRNYEQHRK 179
LA+ K+ L+ ++A D++ E+ + ++Q LE E++R + E +
Sbjct: 1536 SLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDE 1595
Query: 180 ESEDAVKALAKEKDLLE-------REKWELRRQAKEATDHATALRSQLDLKD-------- 224
E E+A ++ K+ +E +K ++ R+ +E L Q++ +D
Sbjct: 1596 EVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLR 1655
Query: 225 NRMKELEAELAMAKQSLATLTKDVPKRHSLA 255
+K +A LA A+ L L P + +A
Sbjct: 1656 KDLKRTKALLADAQLMLDHLKNSAPSKREIA 1686
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/193 (20%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Query: 113 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 172
+L +L + + ++ ALQ +K +RL E D ++ E++ R F
Sbjct: 1406 QLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1465
Query: 173 NYEQHRKESEDAV---KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKE 229
Q +E++ + L +EKD+L E + L++Q +E ++ + +++
Sbjct: 1466 ELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQD 1525
Query: 230 LEAELAMAKQSLATLTKDVPKRHSLAMPGETVLN---GNQEWVVQADLPLTAAIRQSQQT 286
+ ++ + + SLA + K + + E L+ G + + QA L L + + +QT
Sbjct: 1526 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQT 1585
Query: 287 LYHSHPPHPADRQ 299
HS D +
Sbjct: 1586 --HSKEMESRDEE 1596
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 53.5 bits (127), Expect = 3e-07
Identities = 58/214 (27%), Positives = 97/214 (45%), Gaps = 28/214 (13%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSAT-------ELRVQLAQKEQE 124
L E++SRLQ E + ++ E +D+ E + V A+ +L+ QL + +E
Sbjct: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1789
Query: 125 LARAKEALQAMKADRKRLKGEKTD--LVSQMQQLYATLESREEQLRDFIRNYEQHRKESE 182
+E LQA+++ + L+ D LVS+ + LE+R E R ++ E +
Sbjct: 1790 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLK 1849
Query: 183 DAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLA 242
+ ++ L +E+D +R A E + R Q L+D KE ELA + +
Sbjct: 1850 ENMEKLTEERD---------QRIAAENREKEQNKRLQRQLRDT--KEEMGELARKEAEAS 1898
Query: 243 TLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPL 276
K+H L M E++ NQ +QADL L
Sbjct: 1899 R------KKHELEMDLESLEAANQS--LQADLKL 1924
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/178 (24%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKD----LEESQGGKSSEVLSATELRVQLAQKEQELARAK 129
+E+ EEV RQ + K LEE K + EL +LA ++ R
Sbjct: 1588 KEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRD 1647
Query: 130 -EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKAL 188
E+ + ++ D KR K D + L + S+ E I + +ESE A
Sbjct: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-----IAQLKNQLEESEFTCAAA 1702
Query: 189 AKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 246
K + +E E +L Q + TAL QL E++ L ++ + L K
Sbjct: 1703 VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1760
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 28/211 (13%)
Query: 73 REEVSR--LQEEVHLLRQMKEMLAKDLEESQ---GGKSSEVLS----ATELRVQLAQKEQ 123
RE++ R LQ E +L L + LEE G + +V+S ++ Q ++ E
Sbjct: 1476 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEA 1535
Query: 124 ELARAKEALQAMKA---DRKRLKGEKTDLVSQMQQLYATLESREEQLRD-FIRNYEQHRK 179
LA+ K+ L+ ++A D++ E+ + ++Q LE E++R + E +
Sbjct: 1536 SLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDE 1595
Query: 180 ESEDAVKALAKEKDLLE-------REKWELRRQAKEATDHATALRSQLDLKD-------- 224
E E+A ++ K+ +E +K ++ R+ +E L Q++ +D
Sbjct: 1596 EVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLR 1655
Query: 225 NRMKELEAELAMAKQSLATLTKDVPKRHSLA 255
+K +A LA A+ L L P + +A
Sbjct: 1656 KDLKRTKALLADAQLMLDHLKNSAPSKREIA 1686
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/193 (20%), Positives = 83/193 (43%), Gaps = 8/193 (4%)
Query: 113 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 172
+L +L + + ++ ALQ +K +RL E D ++ E++ R F
Sbjct: 1406 QLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1465
Query: 173 NYEQHRKESEDAV---KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKE 229
Q +E++ + L +EKD+L E + L++Q +E ++ + +++
Sbjct: 1466 ELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQD 1525
Query: 230 LEAELAMAKQSLATLTKDVPKRHSLAMPGETVLN---GNQEWVVQADLPLTAAIRQSQQT 286
+ ++ + + SLA + K + + E L+ G + + QA L L + + +QT
Sbjct: 1526 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQT 1585
Query: 287 LYHSHPPHPADRQ 299
HS D +
Sbjct: 1586 --HSKEMESRDEE 1596
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 53.1 bits (126), Expect = 4e-07
Identities = 54/201 (26%), Positives = 100/201 (49%), Gaps = 14/201 (6%)
Query: 72 LREEVSRLQEEV-HLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKE 130
L+EE+S ++ + HL + K++ + E+ Q G + +L +L + E++L A
Sbjct: 377 LKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQS-EINQLHSKLLETERQLGEAHG 435
Query: 131 ALQAMKADRKRLKGEKT-DLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 189
L+ ++++L EK D Q+ L L EEQL++ + N + + + D K
Sbjct: 436 RLK----EQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQL-DKTKQQH 490
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVP 249
+E+ L++ R+A+ D LR Q+ KD +++ LEA L +K++++ L K+
Sbjct: 491 QEQQALQQSTTAKLREAQN--DLEQVLR-QIGDKDQKIQNLEALLQKSKENISLLEKERE 547
Query: 250 KRHSLAMPGE---TVLNGNQE 267
++ GE VLN QE
Sbjct: 548 DLYAKIQAGEGETAVLNQLQE 568
Score = 49.7 bits (117), Expect = 5e-06
Identities = 51/233 (21%), Positives = 100/233 (42%), Gaps = 23/233 (9%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQ-------E 124
L ++ +L+ + ++ KE +DL++ + + L ATEL QL +++ +
Sbjct: 728 LEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLD 787
Query: 125 LARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR----NYEQHRKE 180
L + EAL+++K + + EK L + L + + E+L + I+ ++ + E
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKME 847
Query: 181 SEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQL--------DLKDNRMKELEA 232
E + L+ KD L + L+ E ++ + +LK ++E
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMEN 907
Query: 233 ELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 285
L K+ +L K+ H L + LN QE ++QA L ++ QQ
Sbjct: 908 TLKEQKELKKSLEKEKEASHQLKLE----LNSMQEQLIQAQNTLKQNEKEEQQ 956
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/256 (23%), Positives = 101/256 (39%), Gaps = 45/256 (17%)
Query: 40 CEQCVDAAGPGDRPRAGVPRVRADGDCS-------------QPVLLREEVSRLQEEVHLL 86
C QC+ + G D V G+ S LLR+EV LQ +
Sbjct: 43 CPQCMKSLGSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEE 102
Query: 87 RQMKEMLAKDLEESQGGKSSEVLS---ATELRVQLAQKEQELARA-------KEALQAMK 136
+ E L K+LE+ QG + E T+ +L EQ+L A K+ +
Sbjct: 103 KWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFE 162
Query: 137 ADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKES--------------- 181
+L E D+ S+ + + E+ E+++ R E+ KE+
Sbjct: 163 QKAAQLATEIADIKSKYDEERSLREAAEQKV---TRLTEELNKEATVIQDLKTELLQRPG 219
Query: 182 -EDAV---KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMA 237
ED K L + + L++ E R++++ D L+SQ + + +L +ELA
Sbjct: 220 IEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKG 279
Query: 238 KQSLATLTKDVPKRHS 253
Q +A +++ K S
Sbjct: 280 PQEVAVYVQELQKLKS 295
Score = 43.5 bits (101), Expect = 4e-04
Identities = 42/204 (20%), Positives = 89/204 (43%), Gaps = 33/204 (16%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKD--LEESQGGKSSEVLSATELRV-QLAQKEQELARA 128
L+E+V+ E H L + K+ + L++S K E + E + Q+ K+Q++
Sbjct: 469 LKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNL 528
Query: 129 KEALQAMKADRKRLKGEKTDL-------------VSQMQQLYATLESREEQLRDFIRNYE 175
+ LQ K + L+ E+ DL ++Q+Q+ TL+ + QL + ++N
Sbjct: 529 EALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQS 588
Query: 176 QHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELA 235
+ K++++ L Q +E H A + ++ + + EL ++L
Sbjct: 589 ESHKQAQE-----------------NLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLN 631
Query: 236 MAKQSLATLTKDVPKRHSLAMPGE 259
+K+ ++ L + + L + E
Sbjct: 632 ESKEKVSQLDIQIKAKTELLLSAE 655
Score = 42.4 bits (98), Expect = 8e-04
Identities = 41/190 (21%), Positives = 83/190 (43%), Gaps = 20/190 (10%)
Query: 80 QEEVHLLRQMKEMLAKDLE----ESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAM 135
+++ HL +L+ + SQ +S E +S +L +Q+ K + L A+ A A
Sbjct: 604 EQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVS--QLDIQIKAKTELLLSAEAAKTAQ 661
Query: 136 KADRKR-----------LKGEKTDLVSQMQQLYATLESREE---QLRDFIRNYEQHRKES 181
+AD + + E + +Q+ Q+ A L+ ++E QL ++ Y++
Sbjct: 662 RADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSL 721
Query: 182 EDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
E + L + LE + E++ ++A R + R EL +L M K+ +
Sbjct: 722 EQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIV 781
Query: 242 ATLTKDVPKR 251
++ D+ K+
Sbjct: 782 SSTRLDLQKK 791
Score = 41.6 bits (96), Expect = 0.001
Identities = 67/320 (20%), Positives = 131/320 (40%), Gaps = 36/320 (11%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEV-LSATELRVQLAQKE---QELAR 127
+++++++ +EE +L+Q E L+++ + ++ + + TEL+ +KE EL+
Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELST 857
Query: 128 AKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR-NYEQHRKESEDAVK 186
K+ L + K K E + + LE ++L+ ++ E KE ++ K
Sbjct: 858 VKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKK 917
Query: 187 ALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKE--LEAELAMAKQSLATL 244
+L KEK+ + K EL ++ +++Q LK N +E L+ + KQS
Sbjct: 918 SLEKEKEASHQLKLELNSMQEQ------LIQAQNTLKQNEKEEQQLQGNINELKQS---- 967
Query: 245 TKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRV- 303
+ K+ A+ GE + A L T + QQ L + A+++ + V
Sbjct: 968 -SEQKKKQIEALQGELKI---------AVLQKTELENKLQQQLTQAAQELAAEKEKISVL 1017
Query: 304 ----SPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIV 359
+ SD E + +T D+ S + Q N ++
Sbjct: 1018 QNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLI 1077
Query: 360 QSLE----DLEDQKRKKKKE 375
Q L+ LE KK+++
Sbjct: 1078 QELKTAKATLEQDSAKKEQQ 1097
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/170 (22%), Positives = 83/170 (48%), Gaps = 9/170 (5%)
Query: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATE--LRVQLAQKEQE 124
S+ + R+++ ++E++ L ++ ++++ + K + L + L A+KEQ+
Sbjct: 1040 SELLATRQDLKSVEEKLSLAQE--DLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQ 1097
Query: 125 LARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDA 184
L +ALQ ++ ++ + E + S++ ++ +E+++ + H+ ES
Sbjct: 1098 LQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKE 1157
Query: 185 VKALAKEKDLLEREKWELRRQA---KEATDHATALRSQLDLKDNRMKELE 231
+ L K LL ++K EL+ +A K A + R+Q LKD KE E
Sbjct: 1158 ITNLKDAKQLLIQQKLELQGKADSLKAAVEQEK--RNQQILKDQVKKEEE 1205
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/197 (18%), Positives = 86/197 (43%), Gaps = 8/197 (4%)
Query: 59 RVRADGDCSQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQL 118
+V+ + + L++ + + +E H L+ + + L ++Q +L+ +
Sbjct: 902 QVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNI 961
Query: 119 AQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYA----TLESREEQLRDFIRNY 174
+ +Q + K+ ++A++ + K +KT+L +++QQ L + +E++ NY
Sbjct: 962 NELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNY 1021
Query: 175 EQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAEL 234
E +S++ K L + E E R+ K + + + L N++ +
Sbjct: 1022 E----KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLI 1077
Query: 235 AMAKQSLATLTKDVPKR 251
K + ATL +D K+
Sbjct: 1078 QELKTAKATLEQDSAKK 1094
Score = 36.6 bits (83), Expect = 0.043
Identities = 42/182 (23%), Positives = 82/182 (45%), Gaps = 26/182 (14%)
Query: 74 EEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ 133
++V+RL EE++ + + L +L + G + VL ++VQ L R +E+
Sbjct: 191 QKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERES-- 248
Query: 134 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN-------YEQHRKESEDAVK 186
++LK E L SQ YA+ E+ QLR + Y Q ++ + +V
Sbjct: 249 ------EKLKDECKKLQSQ----YASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVN 298
Query: 187 ALAKEKDLL-------EREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 239
L ++ L E++ +L + E + +++ L KD ++L++ L+ ++
Sbjct: 299 ELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASET 358
Query: 240 SL 241
SL
Sbjct: 359 SL 360
Score = 35.8 bits (81), Expect = 0.073
Identities = 36/174 (20%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 96 DLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 154
++EE + + E+ E L+ + +E+ K+A Q + + L+G+ L + ++
Sbjct: 1128 EIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVE 1187
Query: 155 QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 214
Q E R +Q+ +Q +KE E+ K +++ L E E K+ ++
Sbjct: 1188 Q-----EKRNQQILK-----DQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEA 1237
Query: 215 ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK-RHSLAMPGETVLNGNQE 267
L Q+ + + ++ E +++ ++ L K R +A+ TV N E
Sbjct: 1238 KLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDE 1291
Score = 33.9 bits (76), Expect = 0.28
Identities = 43/199 (21%), Positives = 83/199 (41%), Gaps = 13/199 (6%)
Query: 80 QEEVHLLRQMKEMLAK--DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA 137
QE + Q+ ++ AK D +E S + E + L QK +EL + ++ ++A
Sbjct: 681 QELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEEL---EGQIKKLEA 737
Query: 138 DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLER 197
D +K K + +QQ E + + + E ++ L K+ + LE
Sbjct: 738 DSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797
Query: 198 EKWELRRQAKE----ATDHAT---ALRSQLDLKDNRMKELEAELAMAK-QSLATLTKDVP 249
K +L +Q +E D T + Q + +NR++ EL K + A +T+
Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELST 857
Query: 250 KRHSLAMPGETVLNGNQEW 268
+ L+ +++ N E+
Sbjct: 858 VKDKLSKVSDSLKNSKSEF 876
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 53.1 bits (126), Expect = 4e-07
Identities = 45/187 (24%), Positives = 88/187 (47%), Gaps = 15/187 (8%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA 131
L EE L E+ ++ M E+ + + Q K E L+ QL K+++L K+
Sbjct: 516 LTEEKGTLAGEIRDMKDMLEVKERKINVLQ--KKIE-----NLQEQLRDKDKQLTNLKDR 568
Query: 132 LQAMKADRKRLKGEKTDL---VSQMQQLYATL-ESREEQLRDFIRNYEQHRKESEDAVKA 187
+++++ D L +S+ +++ L E RE R+ + E RKE++D
Sbjct: 569 VKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD---- 624
Query: 188 LAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 247
L ++ + L+ E E + +HA++L S +D+++K LE + K+ + L
Sbjct: 625 LKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQ 684
Query: 248 VPKRHSL 254
+ K H++
Sbjct: 685 LKKAHNI 691
Score = 46.6 bits (109), Expect = 4e-05
Identities = 53/227 (23%), Positives = 105/227 (46%), Gaps = 37/227 (16%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKD----------LEESQGGKSSEV-LSATE---LRVQ 117
L++E+S+ + E+ L+ E L+ L+ES K + TE LR++
Sbjct: 439 LKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLR 498
Query: 118 LAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ-------LYATLESREEQLRDF 170
L +KE L + + LQ + ++ L GE D+ ++ L +E+ +EQLRD
Sbjct: 499 LEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDK 558
Query: 171 ----------IRNYEQHRKESEDAV----KALAKEKDLLEREKWELRRQAKEATDHATAL 216
+++ + ++ A+ +AL++++ ++ER K + R +E + +
Sbjct: 559 DKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESF 618
Query: 217 RSQ-LDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVL 262
R + DLK+ ++ L+AEL + SL L + S + ++ L
Sbjct: 619 RKENKDLKE-KVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKL 664
Score = 34.3 bits (77), Expect = 0.21
Identities = 44/196 (22%), Positives = 85/196 (43%), Gaps = 22/196 (11%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKE-----QELA 126
L+ + LQ+E+ R + +L + E G + TE + Q E +EL
Sbjct: 221 LQLTIQALQDELRTQRDLNHLLQQ--ESGNRGAEHFTIELTEENFRRLQAEHDRQAKELF 278
Query: 127 RAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRK--ESEDA 184
++ L+ M+ + K +++L L+S+ + + E+ R+ E+E
Sbjct: 279 LLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQ 338
Query: 185 VKALA-----KEKDLLE-REKWELRRQAKEATDHATALRSQLDLKDNR-------MKELE 231
V L KEK+ + RE+ R Q + AL++ +++KD + +++LE
Sbjct: 339 VSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLE 398
Query: 232 AELAMAKQSLATLTKD 247
E+ M K + T+D
Sbjct: 399 DEIQMLKANGVLNTED 414
Score = 33.1 bits (74), Expect = 0.48
Identities = 41/197 (20%), Positives = 85/197 (43%), Gaps = 28/197 (14%)
Query: 79 LQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKAD 138
LQ ++ L++ ++L K+L+ S + S +KE+ L + + A ++ +
Sbjct: 150 LQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKE 209
Query: 139 RKRLKGEKTDLVSQMQQLYATLESREEQLR-----DFIRNYEQHRKESEDAVKALAKEKD 193
+ R+ E+ Q L T+++ +++LR + + E + +E L +E
Sbjct: 210 QMRVSHEEN------QHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEEN- 262
Query: 194 LLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK--- 250
R + E RQAKE L L ++E+E + KQ+L + + K
Sbjct: 263 -FRRLQAEHDRQAKE-----------LFLLRKTLEEMELRIETQKQTLNARDESIKKLLE 310
Query: 251 -RHSLAMPGETVLNGNQ 266
S +P +++ + N+
Sbjct: 311 MLQSKGLPSKSLEDDNE 327
Score = 32.7 bits (73), Expect = 0.62
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 9/163 (5%)
Query: 79 LQEEVHLLRQMKEMLAKD----LEESQG-GKSSEVLS--ATELRVQLAQKEQELARAKEA 131
L E+ ++ ++KE +D LEE + K ++ L L+ +L +KE L KE
Sbjct: 590 LSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEH 649
Query: 132 LQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDF--IRNYEQHRKESEDAVKALA 189
++ + + + L ++Q E QL+ I + + E D +K L
Sbjct: 650 ASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLD 709
Query: 190 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 232
KE E + + + + + ++ + KD ++ ELE+
Sbjct: 710 KEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES 752
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 53.1 bits (126), Expect = 4e-07
Identities = 50/264 (18%), Positives = 110/264 (41%), Gaps = 20/264 (7%)
Query: 41 EQCVDAAGPGDRPRAGVPRVRADGDCSQPVL----LREEVSRLQEEVHLLRQMKEMLAKD 96
E+C AA D R V + G Q + +EE+S++++E+ L++ E A
Sbjct: 962 EKCESAAHEADLKRQKV--IELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMH 1019
Query: 97 L-------EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 149
L ++++ + + EL E EL A + + ++ + + GE
Sbjct: 1020 LSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKST 1079
Query: 150 VSQMQQL-------YATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL 202
+ Q+Q+L +LE + ++D + + E ED + L + L+ WEL
Sbjct: 1080 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 1139
Query: 203 RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVL 262
+++A + T +R + ++ +LE L ++ L K + + + L
Sbjct: 1140 KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQL 1199
Query: 263 NGNQEWVVQADLPLTAAIRQSQQT 286
+ ++Q + ++ ++ ++T
Sbjct: 1200 REKEFIMLQNEQEISQLKKEIERT 1223
Score = 45.4 bits (106), Expect = 9e-05
Identities = 42/225 (18%), Positives = 94/225 (41%), Gaps = 48/225 (21%)
Query: 71 LLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKE 130
+L E++ L+ EV ++ LE+SQ + +KEQ L +KE
Sbjct: 288 ILEEQIINLEAEVSAQDKVLREAENKLEQSQ--------------KMVIEKEQSLQESKE 333
Query: 131 ALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKA 187
+ K DL+ Q +Q R E L + + ++Q++K+ + ++
Sbjct: 334 ECIKL----------KVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEK 383
Query: 188 LAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE---------------- 231
+ E+++LER ++ K + +S+L++ ++++L+
Sbjct: 384 VQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVK 443
Query: 232 -----AELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQ 271
A+L ++QS+ L ++ + + +++N N+E V+
Sbjct: 444 NSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVR 488
Score = 38.9 bits (89), Expect = 0.009
Identities = 52/229 (22%), Positives = 100/229 (43%), Gaps = 45/229 (19%)
Query: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKD-----------LEESQGGKSSE------VL 109
+Q +LRE ++L++ ++ + ++ L + LE+++ GK +E +
Sbjct: 302 AQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALY 361
Query: 110 SATELRVQLAQKEQELARAKEALQA-----------MKADRKRL-------KGEKTDLVS 151
+A EL Q ++++A E +QA + + KRL K E L
Sbjct: 362 NAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKE 421
Query: 152 QMQQLYATLESREEQLRDF-IRNYEQHRK--ESEDAVKALAKE---KDLLEREKWELRRQ 205
+++QL + +E+LR ++N E + ES ++ L E KD + R+K+ L +
Sbjct: 422 KLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNE 481
Query: 206 AKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSL 254
+E A +LDL ++ EL +SL + +P + L
Sbjct: 482 NRELKVRVAAQNERLDLCQQEIESSRVEL----RSLEKIISQLPLKREL 526
Score = 38.9 bits (89), Expect = 0.009
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 11/141 (7%)
Query: 112 TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFI 171
++L+V +A + + +E L ++ +L+ E T SQ+ L LE +
Sbjct: 658 SDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIA 717
Query: 172 RN---YEQHRKESEDAVKALAK------EKDLLEREKWEL--RRQAKEATDHATALRSQL 220
EQ E + +++L EK L EK + Q KE L +QL
Sbjct: 718 AKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQL 777
Query: 221 DLKDNRMKELEAELAMAKQSL 241
+ KD + KE E ++M +Q +
Sbjct: 778 EKKDQQFKEQEKTMSMLQQDI 798
Score = 37.0 bits (84), Expect = 0.033
Identities = 39/224 (17%), Positives = 91/224 (40%), Gaps = 12/224 (5%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEA 131
+RE +++++ L E +L+E S + QL +KE + + ++
Sbjct: 1153 IREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQE 1212
Query: 132 LQAMKADRKRLKGEKTDLVSQM--QQLYATLESRE--------EQLRDFIRNYEQHRKES 181
+ +K + +R + ++ S M Q+ Y + +E R+ ++N E+
Sbjct: 1213 ISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEA 1272
Query: 182 EDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 241
+E + L E ++++ +KE H L +L R LEA + + L
Sbjct: 1273 RHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKL 1332
Query: 242 ATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 285
+ + + + + + M + +W + AD ++ + ++Q
Sbjct: 1333 SAEVESLKEAYHMEMISHQ--ENHAKWKISADSQKSSVQQLNEQ 1374
Score = 36.2 bits (82), Expect = 0.056
Identities = 59/276 (21%), Positives = 117/276 (42%), Gaps = 58/276 (21%)
Query: 72 LREEVSRLQEEVHLLRQMKEMLAK---DLEESQGGKSSEVLSATELRVQLAQKEQELARA 128
L+ L+ + L++++++L K LEE E ++++ K+QEL
Sbjct: 1069 LQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEM 1128
Query: 129 KEALQAMKADRK-------------------------RLKG--EKTDLV-----SQMQQL 156
+AL+ + K +L+G EK++L Q++ L
Sbjct: 1129 DQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESL 1188
Query: 157 YATLESREEQLRD--FI-----RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 209
L++ +EQLR+ FI + Q +KE E + + + + +++ ++ + Q KEA
Sbjct: 1189 NDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEA 1248
Query: 210 TDHATALR--------SQLDLKDNRMKELEAE-----LAMAKQSLATLT--KDVPKRHSL 254
D LR S +L + R ++++A+ L+ + + L+ KD H
Sbjct: 1249 IDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLA 1308
Query: 255 AMPGET-VLNGNQEWVVQADLPLTAAIRQSQQTLYH 289
G + V + E +QA++ +A +S + YH
Sbjct: 1309 EELGASKVREAHLEARMQAEIKKLSAEVESLKEAYH 1344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,517,706
Number of Sequences: 37866
Number of extensions: 918936
Number of successful extensions: 10128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 369
Number of HSP's successfully gapped in prelim test: 844
Number of HSP's that attempted gapping in prelim test: 5995
Number of HSP's gapped (non-prelim): 3568
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.