Guide to the Human Genome
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Search of human proteins with 65301128

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|65301128 kazrin isoform C [Homo sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|65301128 kazrin isoform C [Homo sapiens]                           645   0.0  
gi|65301130 kazrin isoform B [Homo sapiens]                           645   0.0  
gi|63999741 kazrin isoform C [Homo sapiens]                           645   0.0  
gi|63147424 kazrin isoform A [Homo sapiens]                           645   0.0  
gi|157837985 kazrin isoform E [Homo sapiens]                          613   e-176
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    56   4e-08
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    56   5e-08
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    55   9e-08
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    55   9e-08
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    54   1e-07
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    54   1e-07
gi|38044112 restin isoform b [Homo sapiens]                            54   2e-07
gi|4506751 restin isoform a [Homo sapiens]                             54   2e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       54   2e-07
gi|45439327 periplakin [Homo sapiens]                                  54   2e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    52   6e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    52   9e-07
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    51   1e-06
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     51   2e-06
gi|92091575 coiled-coil domain containing 57 [Homo sapiens]            51   2e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    51   2e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     50   2e-06
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    50   3e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    50   3e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    50   3e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    50   3e-06
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               50   4e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     50   4e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    49   5e-06
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    49   5e-06

>gi|65301128 kazrin isoform C [Homo sapiens]
          Length = 327

 Score =  645 bits (1665), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
           MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60

Query: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
           LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120

Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
           ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180

Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
           VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240

Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
           SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300

Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
           GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327


>gi|65301130 kazrin isoform B [Homo sapiens]
          Length = 415

 Score =  645 bits (1665), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
           MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 89  MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 148

Query: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
           LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 149 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 208

Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
           ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 209 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 268

Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
           VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 269 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 328

Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
           SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 329 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 388

Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
           GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 389 GKQRKSLDPGLFDGTAPDYYIEEDADW 415


>gi|63999741 kazrin isoform C [Homo sapiens]
          Length = 327

 Score =  645 bits (1665), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
           MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60

Query: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
           LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120

Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
           ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180

Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
           VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240

Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
           SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300

Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
           GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327


>gi|63147424 kazrin isoform A [Homo sapiens]
          Length = 421

 Score =  645 bits (1665), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
           MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 95  MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 154

Query: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
           LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 155 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 214

Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
           ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 215 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 274

Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
           VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 275 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 334

Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
           SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 335 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 394

Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
           GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 395 GKQRKSLDPGLFDGTAPDYYIEEDADW 421


>gi|157837985 kazrin isoform E [Homo sapiens]
          Length = 775

 Score =  613 bits (1582), Expect = e-176
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
           MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 95  MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 154

Query: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
           LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 155 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 214

Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
           ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 215 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 274

Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
           VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 275 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 334

Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
           SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 335 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 394

Query: 301 GKQRKSLDPGLFD 313
           GKQRKSLDPGLFD
Sbjct: 395 GKQRKSLDPGLFD 407


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 44/169 (26%), Positives = 81/169 (47%), Gaps = 15/169 (8%)

Query: 10  EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
           E S+  +  ++L   +LR Q   K Q LA  ++ ++  K  R+RL+ ++       +Q  
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424

Query: 70  ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
                RE++ +  +   E+ RKE E+  +A  +EK  +ERE+  +RRQ +E   H   L+
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483

Query: 130 SQL-------------DLKDNRMKE-LEAELAMAKQSLATLTKDVPKRH 164
            QL             +++++R  E L+ +L   +  L +L  D  + H
Sbjct: 484 QQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPH 532


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
           sapiens]
          Length = 1935

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 47/161 (29%), Positives = 73/161 (45%), Gaps = 17/161 (10%)

Query: 16  KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
           K   +L + E   ++A  ++E  R KEAL+  +A RK L+        EK DL  Q+Q  
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 894

Query: 69  YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
              L   EE+    I+N  Q          R E E+ + A L  +K  LE E  EL+R  
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954

Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
            +       +  +    +N++K L  E+A   + +A LTK+
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 46/166 (27%), Positives = 73/166 (43%), Gaps = 26/166 (15%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA----DRKRLKGEK 58
            + + +DLEE+         +A  LR + A    EL    + LQ +K     ++   K E 
Sbjct: 1172 QKMRRDLEEAT---LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 59   TDLVSQMQQLY---ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
             D+ S M+Q+    A LE     L D +  +    +E++ +V  L  ++  L+ E  EL 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 116  RQAKEATDHATALRSQL------------DLKDNRMKELEAELAMA 149
            RQ     D   AL SQL            DLK    +E++A+ A+A
Sbjct: 1289 RQ----LDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 8/157 (5%)

Query: 10   EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
            EESQ    S    A  L  +L + +     + E L+  K + K L+ E +DL  Q+    
Sbjct: 1461 EESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSG 1520

Query: 70   ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL--------RRQAKEA 121
             T+   E+  +       + +   E+A  +L  E+  + R + E         R+ A++ 
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580

Query: 122  TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
             +   A R+ L + D+    L+AE     ++L    K
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 10/148 (6%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
            E L + LEE    K+     A    +Q A+ + +L R + E     KA+ +R+  +    
Sbjct: 1313 EDLKRQLEEEVKAKN-----ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1367

Query: 62   VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            V+Q +  Y T    R E+L +  +   Q  +E+E+AV+A+  +   LE+ K  L+ + ++
Sbjct: 1368 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIED 1427

Query: 121  A---TDHATALRSQLDLKDNRMKELEAE 145
                 + + A  + LD K     ++ AE
Sbjct: 1428 LMVDVERSNAAAAALDKKQRNFDKILAE 1455



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 35/149 (23%), Positives = 70/149 (46%), Gaps = 28/149 (18%)

Query: 25   ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
            E + +LAQ+ QE   A EA+ A    ++  + RL+ E  DL+  +++  A   + +++ R
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1447

Query: 81   DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ------ 131
            +F   +  ++Q  +ES+  +++  KE   L  E ++L+   +E+ +H    + +      
Sbjct: 1448 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1507

Query: 132  --LDLKDNR-------------MKELEAE 145
               DL +                K+LEAE
Sbjct: 1508 EISDLTEQLGSSGKTIHELEKVRKQLEAE 1536



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 7/132 (5%)

Query: 27   RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
            ++QL  K +E+    E  + M A+    +++L+ E ++L   +  L  TL   E  +   
Sbjct: 912  KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971

Query: 80   RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
             + ++N  +     ++ +  L KEK  L+    +     +   D    L       + ++
Sbjct: 972  ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031

Query: 140  KELEAELAMAKQ 151
             +LE  L   K+
Sbjct: 1032 DDLEGSLEQEKK 1043



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 8/130 (6%)

Query: 25   ELRVQLAQKEQELARAK-----EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL 79
            EL +   +KE+     K     E +  +     +L  EK  L    QQ    L++ E+++
Sbjct: 958  ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017

Query: 80   RDFIRNYEQHRKESEDAVKALAKEKDL---LEREKWELRRQAKEATDHATALRSQLDLKD 136
                +   +  ++ +D   +L +EK +   LER K +L    K   +    L +     D
Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077

Query: 137  NRMKELEAEL 146
             R+K+ + EL
Sbjct: 1078 ERLKKKDFEL 1087



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 29/157 (18%), Positives = 73/157 (46%), Gaps = 4/157 (2%)

Query: 4    MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKE-ALQAMKADRKRLKGEKTDLV 62
            M+A++L++ Q   +        +   +   +  L  A++ AL+  K   ++L+    +L 
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823

Query: 63   SQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL---RRQAK 119
            ++++          + +R   R  ++   ++E+  K L + +DL+++ + ++   +RQA+
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883

Query: 120  EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
            EA + A    S+     + + E E    +A+  +  L
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1920


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 1/123 (0%)

Query: 10  EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
           E S+  +  ++L   +LR Q   K Q LA  ++ ++  K  R+RL+ ++       +Q  
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424

Query: 70  ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
                RE++ +  +   E+ RKE E+  +A  +EK  +ERE+  +RRQ +E   H   L+
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483

Query: 130 SQL 132
            QL
Sbjct: 484 QQL 486


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 1/123 (0%)

Query: 10  EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
           E S+  +  ++L   +LR Q   K Q LA  ++ ++  K  R+RL+ ++       +Q  
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424

Query: 70  ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
                RE++ +  +   E+ RKE E+  +A  +EK  +ERE+  +RRQ +E   H   L+
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483

Query: 130 SQL 132
            QL
Sbjct: 484 QQL 486


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/143 (25%), Positives = 68/143 (47%)

Query: 26  LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
           L+ QL  KE++++  KE +++++AD        T L   + +   T+E  +EQ     R 
Sbjct: 583 LQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE 642

Query: 86  YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAE 145
            ++     +  +K L ++  LL+ +  E      +  +HA++L S    KD+R+K LE  
Sbjct: 643 KQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIA 702

Query: 146 LAMAKQSLATLTKDVPKRHSLAM 168
           L   K+    +   + K H  A+
Sbjct: 703 LEQKKEECLKMESQLKKAHEAAL 725



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 53/213 (24%), Positives = 96/213 (45%), Gaps = 17/213 (7%)

Query: 2   KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK----EALQAMKADRKRLKGE 57
           K+   K LE +   K  E L   E +++ A +    ARA     + +Q ++ +  R K E
Sbjct: 692 KDSRLKTLEIALEQKKEECLKM-ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDE 750

Query: 58  KTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA--KEKDLLEREKW--- 112
            +   +++ +L   L+  E +  D  +   +  ++ +D  K +A  K K+ +E++K    
Sbjct: 751 SSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQM 810

Query: 113 --ELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLA----TLTKDVPKRHSL 166
             E RR+     D +  L+  L  KD+R++ELE  L  + Q  A     L ++   R + 
Sbjct: 811 LEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNA 870

Query: 167 AMPGETVLNGNQEWVVQADLPLTAAIRQSQQTL 199
               E +L    E V Q    + A +  +QQ+L
Sbjct: 871 EKQVEELLMA-MEKVKQELESMKAKLSSTQQSL 902



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 35/185 (18%), Positives = 77/185 (41%), Gaps = 24/185 (12%)

Query: 3   EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
           E L ++L   +         A  L+ ++ Q +QEL+R    L A++   + L  + +D  
Sbjct: 441 EQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 500

Query: 63  SQMQQLYATLESREEQ----------LRDFIRNYEQHRKESEDAVKALAKEK-------- 104
             ++ L  +L ++E++          LR  +   E    +    ++ +A+EK        
Sbjct: 501 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 560

Query: 105 ------DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
                 D+ ER+   L+++ +   +       Q+     R+K L+A+      +L TL +
Sbjct: 561 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 620

Query: 159 DVPKR 163
            + ++
Sbjct: 621 ALAEK 625



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 44/222 (19%), Positives = 92/222 (41%), Gaps = 22/222 (9%)

Query: 9    LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQL 68
            +EE +      V    E  + LAQ+E     A++ ++ +    +++K E   + +++   
Sbjct: 839  IEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSST 898

Query: 69   YATLESREEQLRDFIRNYEQHRKE----SEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
              +L  +E  L +      +H +E     ++A+ A   EKD       EL    K+  + 
Sbjct: 899  QQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD-ANIALLELSSSKKKTQEE 957

Query: 125  ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQA 184
              AL+ +   KD  +++L+ +     + +A   +D   + S +   +T    + + ++Q 
Sbjct: 958  VAALKRE---KDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHS--NQTNHKPSPDQIIQP 1012

Query: 185  DLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVI 226
             L L     +S+  LY  H            + CH R P ++
Sbjct: 1013 LLELDQ--NRSKLKLYIGH----------LTTLCHDRDPLIL 1042



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 17/143 (11%)

Query: 26  LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
           LR  L + E  +   K+ L A     K+L      L S+     AT E  E   R  +  
Sbjct: 284 LRKTLEEMELRIETQKQTLNARDESIKKLLEM---LQSKGLSAKATEEDHERTRR--LAE 338

Query: 86  YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT--ALRSQLDLKDNR----- 138
            E H    E  ++   KE  +L  E   + R+ + A D A   AL++ +++KD++     
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREE---MHRRFENAPDSAKTKALQTVIEMKDSKISSME 395

Query: 139 --MKELEAELAMAKQSLATLTKD 159
             +++LE E+ M K + A  T++
Sbjct: 396 RGLRDLEEEIQMLKSNGALSTEE 418



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 39/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)

Query: 3   EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA-------DRKRLK 55
           + L + L+E +  K+ +     EL  Q+  + +++A  K   Q  K        + +R +
Sbjct: 759 DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE 818

Query: 56  GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQ------------------HRKESEDAV 97
               D   Q+Q      + R E+L + +R   Q                    K+ E+ +
Sbjct: 819 DNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELL 878

Query: 98  KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
            A+ K K  LE  K +L    +   +  T L    +L+  R K LE  L M +++L
Sbjct: 879 MAMEKVKQELESMKAKLSSTQQSLAEKETHL---TNLRAERRKHLEEVLEMKQEAL 931



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 60  DLVSQMQQLYA----TLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
           DL  ++Q L +    + E REE+++  +  Y  H K  ++ V+ L +E    E +  EL+
Sbjct: 400 DLEEEIQMLKSNGALSTEEREEEMKQ-MEVYRSHSKFMKNKVEQLKEELSSKEAQWEELK 458

Query: 116 RQAKEATDHATALRSQLDLKDNRMKELEAEL 146
           ++A         ++ +L  KD  +  L+ +L
Sbjct: 459 KKAAGLQAEIGQVKQELSRKDTELLALQTKL 489


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/143 (25%), Positives = 68/143 (47%)

Query: 26  LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
           L+ QL  KE++++  KE +++++AD        T L   + +   T+E  +EQ     R 
Sbjct: 555 LQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE 614

Query: 86  YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAE 145
            ++     +  +K L ++  LL+ +  E      +  +HA++L S    KD+R+K LE  
Sbjct: 615 KQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIA 674

Query: 146 LAMAKQSLATLTKDVPKRHSLAM 168
           L   K+    +   + K H  A+
Sbjct: 675 LEQKKEECLKMESQLKKAHEAAL 697



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 53/213 (24%), Positives = 96/213 (45%), Gaps = 17/213 (7%)

Query: 2   KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK----EALQAMKADRKRLKGE 57
           K+   K LE +   K  E L   E +++ A +    ARA     + +Q ++ +  R K E
Sbjct: 664 KDSRLKTLEIALEQKKEECLKM-ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDE 722

Query: 58  KTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA--KEKDLLEREKW--- 112
            +   +++ +L   L+  E +  D  +   +  ++ +D  K +A  K K+ +E++K    
Sbjct: 723 SSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQM 782

Query: 113 --ELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLA----TLTKDVPKRHSL 166
             E RR+     D +  L+  L  KD+R++ELE  L  + Q  A     L ++   R + 
Sbjct: 783 LEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNA 842

Query: 167 AMPGETVLNGNQEWVVQADLPLTAAIRQSQQTL 199
               E +L    E V Q    + A +  +QQ+L
Sbjct: 843 EKQVEELLMA-MEKVKQELESMKAKLSSTQQSL 874



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 44/222 (19%), Positives = 92/222 (41%), Gaps = 22/222 (9%)

Query: 9    LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQL 68
            +EE +      V    E  + LAQ+E     A++ ++ +    +++K E   + +++   
Sbjct: 811  IEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSST 870

Query: 69   YATLESREEQLRDFIRNYEQHRKE----SEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
              +L  +E  L +      +H +E     ++A+ A   EKD       EL    K+  + 
Sbjct: 871  QQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD-ANIALLELSSSKKKTQEE 929

Query: 125  ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQA 184
              AL+ +   KD  +++L+ +     + +A   +D   + S +   +T    + + ++Q 
Sbjct: 930  VAALKRE---KDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHS--NQTNHKPSPDQIIQP 984

Query: 185  DLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVI 226
             L L     +S+  LY  H            + CH R P ++
Sbjct: 985  LLELDQ--NRSKLKLYIGH----------LTTLCHDRDPLIL 1014



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 17/143 (11%)

Query: 26  LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
           LR  L + E  +   K+ L A     K+L      L S+     AT E  E   R  +  
Sbjct: 284 LRKTLEEMELRIETQKQTLNARDESIKKLLEM---LQSKGLSAKATEEDHERTRR--LAE 338

Query: 86  YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT--ALRSQLDLKDNR----- 138
            E H    E  ++   KE  +L  E   + R+ + A D A   AL++ +++KD++     
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREE---MHRRFENAPDSAKTKALQTVIEMKDSKISSME 395

Query: 139 --MKELEAELAMAKQSLATLTKD 159
             +++LE E+ M K + A  T++
Sbjct: 396 RGLRDLEEEIQMLKSNGALSTEE 418



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 39/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)

Query: 3   EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA-------DRKRLK 55
           + L + L+E +  K+ +     EL  Q+  + +++A  K   Q  K        + +R +
Sbjct: 731 DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE 790

Query: 56  GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQ------------------HRKESEDAV 97
               D   Q+Q      + R E+L + +R   Q                    K+ E+ +
Sbjct: 791 DNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELL 850

Query: 98  KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
            A+ K K  LE  K +L    +   +  T L    +L+  R K LE  L M +++L
Sbjct: 851 MAMEKVKQELESMKAKLSSTQQSLAEKETHL---TNLRAERRKHLEEVLEMKQEAL 903



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 27/135 (20%), Positives = 57/135 (42%), Gaps = 4/135 (2%)

Query: 29  QLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQ 88
           Q +  +Q +   KE+L A +     L+ E   L  ++++    L  + +Q++D       
Sbjct: 467 QFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGT 526

Query: 89  HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM 148
              E  D    L    D+ ER+   L+++ +   +       Q+     R+K L+A+   
Sbjct: 527 QAGEIHDLKDML----DVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 582

Query: 149 AKQSLATLTKDVPKR 163
              +L TL + + ++
Sbjct: 583 TDTALTTLEEALAEK 597


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 40/171 (23%), Positives = 79/171 (46%), Gaps = 15/171 (8%)

Query: 5   LAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEAL----QAMKADRKRLKGEKT 59
           + K+ E S+    +  L   EL++  L +   E+++ KE L    Q +K        E  
Sbjct: 763 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAV 822

Query: 60  DLVSQMQQLYATLESREEQ----------LRDFIRNYEQHRKESEDAVKALAKEKDLLER 109
            +   MQ+    L  +EEQ          LR+ + + E   +E ++  + L K K+ LE 
Sbjct: 823 SVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEN 882

Query: 110 EKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
           +  E+ + + + +   T +  +L LK+  ++EL+ +L  A ++ + L K +
Sbjct: 883 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSI 933



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)

Query: 22   SATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQM-------QQLYATLES 74
            S  ++ V+  Q +QE A+  E       ++K L+ + +DL  +M       Q+L A  E 
Sbjct: 932  SIEDMTVKAEQSQQEAAKKHEE------EKKELERKLSDLEKKMETSHNQCQELKARYER 985

Query: 75   REEQLR----DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRS 130
               + +    + ++N ++   ++ED +K   +E   L +E  ELR+QA +A    TA   
Sbjct: 986  ATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTA-ED 1044

Query: 131  QLDLKDNRMKELEAELAMAKQSLATLTK 158
             + + +   KE    LA  + +  T  K
Sbjct: 1045 AMQIMEQMTKEKTETLASLEDTKQTNAK 1072



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 9/157 (5%)

Query: 7   KDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 66
           +D E +   K  E L A  ++V + +KE  L   +  L   KA+ + L  E  D ++++Q
Sbjct: 635 QDSERAAHAKEMEALRAKLMKV-IKEKENSLEAIRSKLD--KAEDQHLV-EMEDTLNKLQ 690

Query: 67  QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 126
           +  A ++ +E ++     N EQ +       +  A E+ LL+ +   LR+ + E      
Sbjct: 691 E--AEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDA--LRKASSEGKSEMK 745

Query: 127 ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKR 163
            LR QL+  + ++K LE E        +++T+++  R
Sbjct: 746 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR 782



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 36/163 (22%), Positives = 79/163 (48%), Gaps = 15/163 (9%)

Query: 4   MLAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
           ML+ DLE     K  E L+  E +  +  ++E++L +AKE L+   A+  ++ G+ +  +
Sbjct: 844 MLSSDLE-----KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQL 898

Query: 63  SQMQQLYATLESREEQLRDFIRNYEQH----RKESED-AVKALAKEKDLLEREKWELRRQ 117
           ++M       E   E+L+  +    ++    +K  ED  VKA   +++  ++ + E +  
Sbjct: 899 TKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKEL 958

Query: 118 AKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
            ++ +D    L  +++   N+ +EL+A    A     T  +++
Sbjct: 959 ERKLSD----LEKKMETSHNQCQELKARYERATSETKTKHEEI 997



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 31/140 (22%), Positives = 61/140 (43%)

Query: 24  TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFI 83
           TE   + A+K       +EAL+  +   ++L  E+    +++ +  + +   E++L    
Sbjct: 337 TETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR 396

Query: 84  RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
             ++QH  E E  +  L    +  +REK EL  Q +E       L+ +++ +     +LE
Sbjct: 397 DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE 456

Query: 144 AELAMAKQSLATLTKDVPKR 163
                 K  +  L KD+  R
Sbjct: 457 VATVSEKSRIMELEKDLALR 476


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 40/171 (23%), Positives = 79/171 (46%), Gaps = 15/171 (8%)

Query: 5   LAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEAL----QAMKADRKRLKGEKT 59
           + K+ E S+    +  L   EL++  L +   E+++ KE L    Q +K        E  
Sbjct: 798 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAV 857

Query: 60  DLVSQMQQLYATLESREEQ----------LRDFIRNYEQHRKESEDAVKALAKEKDLLER 109
            +   MQ+    L  +EEQ          LR+ + + E   +E ++  + L K K+ LE 
Sbjct: 858 SVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEN 917

Query: 110 EKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
           +  E+ + + + +   T +  +L LK+  ++EL+ +L  A ++ + L K +
Sbjct: 918 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSI 968



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)

Query: 22   SATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQM-------QQLYATLES 74
            S  ++ V+  Q +QE A+  E       ++K L+ + +DL  +M       Q+L A  E 
Sbjct: 967  SIEDMTVKAEQSQQEAAKKHEE------EKKELERKLSDLEKKMETSHNQCQELKARYER 1020

Query: 75   REEQLR----DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRS 130
               + +    + ++N ++   ++ED +K   +E   L +E  ELR+QA +A    TA   
Sbjct: 1021 ATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTA-ED 1079

Query: 131  QLDLKDNRMKELEAELAMAKQSLATLTK 158
             + + +   KE    LA  + +  T  K
Sbjct: 1080 AMQIMEQMTKEKTETLASLEDTKQTNAK 1107



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 9/157 (5%)

Query: 7   KDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 66
           +D E +   K  E L A  ++V + +KE  L   +  L   KA+ + L  E  D ++++Q
Sbjct: 670 QDSERAAHAKEMEALRAKLMKV-IKEKENSLEAIRSKLD--KAEDQHLV-EMEDTLNKLQ 725

Query: 67  QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 126
           +  A ++ +E ++     N EQ +       +  A E+ LL+ +   LR+ + E      
Sbjct: 726 E--AEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDA--LRKASSEGKSEMK 780

Query: 127 ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKR 163
            LR QL+  + ++K LE E        +++T+++  R
Sbjct: 781 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR 817



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 36/163 (22%), Positives = 79/163 (48%), Gaps = 15/163 (9%)

Query: 4    MLAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            ML+ DLE     K  E L+  E +  +  ++E++L +AKE L+   A+  ++ G+ +  +
Sbjct: 879  MLSSDLE-----KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQL 933

Query: 63   SQMQQLYATLESREEQLRDFIRNYEQH----RKESED-AVKALAKEKDLLEREKWELRRQ 117
            ++M       E   E+L+  +    ++    +K  ED  VKA   +++  ++ + E +  
Sbjct: 934  TKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKEL 993

Query: 118  AKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
             ++ +D    L  +++   N+ +EL+A    A     T  +++
Sbjct: 994  ERKLSD----LEKKMETSHNQCQELKARYERATSETKTKHEEI 1032



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 30/137 (21%), Positives = 60/137 (43%), Gaps = 6/137 (4%)

Query: 3   EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMK--ADRKRLKGEKTD 60
           + L ++LE+++    SE     EL   LA + QE+A  +  L++ K   D         +
Sbjct: 481 DKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQE 540

Query: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLERE----KWELRR 116
           + S  ++L  T    + ++     ++    +  +  +KAL    + L +E    K +L  
Sbjct: 541 ISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 600

Query: 117 QAKEATDHATALRSQLD 133
             KE +D     +S+L+
Sbjct: 601 ANKENSDVIALWKSKLE 617



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 14/151 (9%)

Query: 24  TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFI 83
           TE   + A+K       +EAL+  +   ++L  E+    +++ +  + +   E++L    
Sbjct: 337 TETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR 396

Query: 84  RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR-------------- 129
             ++QH  E E  +  L    +  +REK EL  Q +E       L+              
Sbjct: 397 DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE 456

Query: 130 SQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
           +Q  L+  R+KELE  L   K     L +++
Sbjct: 457 TQTKLEHARIKELEQSLLFEKTKADKLQREL 487


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 17/161 (10%)

Query: 16  KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
           K   +L + E   ++A  ++E  R KE L+  +A RK L+        EK DL  Q+Q  
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 896

Query: 69  YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
              L   EE+    I+N  Q          R E E+ + A L  +K  LE E  EL++  
Sbjct: 897 QDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956

Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
            +       +  +    +N++K L  E+A   + +A LTK+
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 997



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 31/141 (21%), Positives = 71/141 (50%), Gaps = 7/141 (4%)

Query: 25   ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
            E + +LAQ+ Q+   A EA+ A    ++  + RL+ E  DL+  +++  A   + +++ R
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449

Query: 81   DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            +F   +  ++Q  +ES+  +++  KE   L  E ++L+   +E+ +H    + +      
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509

Query: 138  RMKELEAELAMAKQSLATLTK 158
             + +L  +L    +++  L K
Sbjct: 1510 EISDLTEQLGEGGKNVHELEK 1530



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 55/257 (21%), Positives = 102/257 (39%), Gaps = 18/257 (7%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA----DRKRLKGEK 58
            + + +DLEE+         +A  LR + A    EL    + LQ +K     ++   K E 
Sbjct: 1174 QKMRRDLEEAT---LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1230

Query: 59   TDLVSQMQQLY---ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
             D+ S M+Q+    A LE     L D    Y    +E++ ++     ++  L+ E  EL 
Sbjct: 1231 DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELA 1290

Query: 116  RQAKEATDHATALRSQLDLKDNRMKELEAEL---AMAKQSLATLTKDVPKRHSLAMPGET 172
            RQ +E     + L         +M++L+ +L     AK +LA   +    RH   +  E 
Sbjct: 1291 RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSA--RHDCDLLREQ 1348

Query: 173  VLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAA 232
                 +E   +A+L    +   S+   + +     A ++   +     +    + DA  A
Sbjct: 1349 Y---EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEA 1405

Query: 233  EGDRSSTPSDINSPRHR 249
                ++  S +   +HR
Sbjct: 1406 VEAVNAKCSSLEKTKHR 1422



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 38/148 (25%), Positives = 72/148 (48%), Gaps = 10/148 (6%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
            E L + LEE   GK+   L+     +Q A+ + +L R + E     KA+ +R+  +    
Sbjct: 1315 EDLKRQLEEE--GKAKNALAHA---LQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1369

Query: 62   VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            V+Q +  Y T    R E+L +  +   Q  +++E+AV+A+  +   LE+ K  L+ + ++
Sbjct: 1370 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIED 1429

Query: 121  A---TDHATALRSQLDLKDNRMKELEAE 145
                 + + A  + LD K     ++ AE
Sbjct: 1430 LMVDVERSNAAAAALDKKQRNFDKILAE 1457



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 26/132 (19%), Positives = 56/132 (42%), Gaps = 7/132 (5%)

Query: 27   RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
            ++QL  K +E+    E  + M A+    +++L+ E ++L   +  L  TL   E  +   
Sbjct: 914  KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 973

Query: 80   RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
             + ++N  +     ++ +  L KEK  L+    +     +   D   +L       + ++
Sbjct: 974  ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQV 1033

Query: 140  KELEAELAMAKQ 151
             +LE  L   K+
Sbjct: 1034 DDLEGSLEQEKK 1045



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 30/163 (18%), Positives = 79/163 (48%), Gaps = 16/163 (9%)

Query: 4    MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVS 63
            M+A++L++ Q   +        +   +   +  L  A++   A+K  +K+L+     L +
Sbjct: 1766 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQI--ALKGGKKQLQ----KLEA 1819

Query: 64   QMQQLYATLESREEQLRDFIRNYEQHRK-------ESEDAVKALAKEKDLLEREKWEL-- 114
            ++++L   LE+ +++  + ++   +  +       ++E+  K L + +DL+++ + ++  
Sbjct: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879

Query: 115  -RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
             +RQA+EA + A    S+     + + E E    +A+  +  L
Sbjct: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1922


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 49/187 (26%), Positives = 87/187 (46%), Gaps = 36/187 (19%)

Query: 29   QLAQKEQELARAKEA--------------------------------LQAMKADRKRLKG 56
            Q+A+KE+EL+R KE                                 +  ++A+ +RL+ 
Sbjct: 1335 QIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQR 1394

Query: 57   EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR 116
             +T+L  Q+++L    ++R E  R+  R   Q R  + +  +A A+EK +   +K  L++
Sbjct: 1395 RRTELERQLEELERERQARREAEREVQR--LQQRLAALEQEEAEAREK-VTHTQKVVLQQ 1451

Query: 117  QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG 176
              ++A +HA  LR QL+ + +R + LE EL   ++ LA L K   K   +      V  G
Sbjct: 1452 DPQQAREHA-LLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1510

Query: 177  NQEWVVQ 183
            + E  +Q
Sbjct: 1511 DTEQEIQ 1517



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 12/159 (7%)

Query: 1    MKEMLAKDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAMKADRKRLKGEKT 59
            +KE+L  + + +Q  +  ++    E LR Q   +E E+   ++ + A+  ++ R + + T
Sbjct: 994  VKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVT 1053

Query: 60   DLVSQMQQLYATLESREEQLRDFIRNYEQHRKESE-------DAVKALAKEKDLLEREKW 112
            +      Q    LE+  +QL++  +  +Q R++ E       D +K L KE+ + E  K 
Sbjct: 1054 EKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAE-GKI 1112

Query: 113  ELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 151
             ++   K   D AT  R   DL   R  E EA  A A Q
Sbjct: 1113 TVKEVLKVEKDAATE-REVSDL--TRQYEDEAAKARASQ 1148



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 33/162 (20%), Positives = 70/162 (43%), Gaps = 16/162 (9%)

Query: 1   MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
           ++++ A   +  Q  K  E L A +LR  L  +    +   +  + +++   ++K E+  
Sbjct: 784 VQKICANSQQYQQAVKDYE-LEAEKLRSLLDLENGRSSHVSKRAR-LQSPATKVKEEEAA 841

Query: 61  LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
           L ++  ++YA    R + L +F  N  + + E E   + L              R +   
Sbjct: 842 LAAKFTEVYAINRQRLQNL-EFALNLLRQQPEVEVTHETLQ-------------RNRPDS 887

Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK 162
             + A  +R +LD +  R ++LE E+   ++ + TL    P+
Sbjct: 888 GVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQ 929



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 24/163 (14%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E   ++LE  +  +         L+ +LA  EQE A A+E         K    +K  L 
Sbjct: 1400 ERQLEELERERQARREAEREVQRLQQRLAALEQEEAEARE---------KVTHTQKVVLQ 1450

Query: 63   SQMQQLYATLESREEQLRDFIRNYEQHRKE-SEDAVKALAKEKDLLE----REKWELRRQ 117
               QQ      +RE  L       EQHR++  E  ++ L ++   LE    +EK  L   
Sbjct: 1451 QDPQQ------AREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSES 1504

Query: 118  AK----EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
             +    +       L+S L+ +    +EL+ E++  +  L+ L
Sbjct: 1505 VQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSEL 1547


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 63/308 (20%), Positives = 127/308 (41%), Gaps = 63/308 (20%)

Query: 22   SATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRD 81
            +A  L VQ+ + ++  A   + L+A K  +++   E    V+++++L   L+  ++QL+ 
Sbjct: 1081 NAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQK 1140

Query: 82   FIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKE 141
             ++  E  +K+        A++  L+  E  +  R  KE       L  +L  K+N++++
Sbjct: 1141 TMQELELVKKD--------AQQTTLMNMEIADYERLMKE-------LNQKLTNKNNKIED 1185

Query: 142  LEAELAMAKQSLATLTKDVPKRHS---------------LAMPGETVLNGNQ----EWVV 182
            LE E+ + KQ   TL +++    S               L    + + +  Q      ++
Sbjct: 1186 LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLIL 1245

Query: 183  QADLPLTAAIRQSQQTLY--------------HSHPPHPADRQAVRVSPCHSRQPSVISD 228
            QA L       Q Q  +Y              H H    A++    +S    R  ++  +
Sbjct: 1246 QASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEE 1305

Query: 229  ASAAEGDRSSTPSDINSPRHRTH---------SLCNGDSPGPVQKNLHNPIVQSLEDLED 279
              AA+ ++++  S+  S + R H         S+   ++ G  Q+  H      LE L D
Sbjct: 1306 CRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREH------LEMLID 1359

Query: 280  QKRKKKKE 287
            Q + K ++
Sbjct: 1360 QLKIKLQD 1367



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 12/162 (7%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E L K+ +E +   +   L A + + +L    +E    KE L+++++++ +L     DL+
Sbjct: 954  ENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLI 1013

Query: 63   ---SQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR 116
                  + L    E + EQL   ++   N+E   ++    ++    + + +  +  +L  
Sbjct: 1014 QGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLA 1073

Query: 117  QAKEATDHATALRSQLDLKDNRM-----KELEAELAMAKQSL 153
            + +    +A  L  Q+ L+  R      KELEAE    +Q +
Sbjct: 1074 RIETLQSNAKLLEVQI-LEVQRAKAMVDKELEAEKLQKEQKI 1114



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 37/178 (20%), Positives = 76/178 (42%), Gaps = 22/178 (12%)

Query: 4    MLAKDLEESQGGKSSEVLSATEL--RVQLAQKE-------------------QELARAKE 42
            +L   L +S   K+  + S  EL  +++  +KE                   +EL  +++
Sbjct: 927  LLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRK 986

Query: 43   ALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAK 102
              Q +K + + L+ EK  L + M+ L    ES +  L ++ +  EQ   E E A     +
Sbjct: 987  ETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHR 1046

Query: 103  EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
             +D L R+      Q +        L ++++   +  K LE ++   +++ A + K++
Sbjct: 1047 IED-LTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKEL 1103



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 25/169 (14%)

Query: 16  KSSEVLSATELRVQLAQKEQ----------ELARAKEALQA----MKADRKRLKGEKTDL 61
           +   V+   EL+  L   EQ          E+   KEALQ+    MK   ++ + E  +L
Sbjct: 819 QEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNL 878

Query: 62  VSQMQQLYATLESRE---EQLRDFIRNYEQ-----HRKESEDAVKALAKEKDLLERE--- 110
           + Q++++  T    E   E+ + FI+ +E       +KE  D    L   KD L +    
Sbjct: 879 LIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSV 938

Query: 111 KWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
           K +     KE  +    L  +   K+ ++ +++     AK+ L +  K+
Sbjct: 939 KNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKE 987



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 12/90 (13%)

Query: 44  LQAMKADRKRLKGEKTDLVSQMQQLYATLESRE-----------EQLRDFIRNYEQHRKE 92
           LQA+     ++  EK +L  Q  +    LE              E+L+  +R+YEQ +  
Sbjct: 783 LQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVL 842

Query: 93  SEDAVKALAKEKDLLEREKWELRRQAKEAT 122
               ++ +  EK+ L+ +  E+ + A E T
Sbjct: 843 LRKELEEIQSEKEALQSDLLEM-KNANEKT 871


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
           [Homo sapiens]
          Length = 1937

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 17/161 (10%)

Query: 16  KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
           K   +L + E   ++A  ++E  + K+ L   +A RK L+        EK DL  Q+Q  
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897

Query: 69  YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
             +L   EE+    I+N  Q          R E E+ + A L  +K  LE E  EL++  
Sbjct: 898 ADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI 957

Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
            +       +  +    +N++K L  E+A   +++A L+K+
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKE 998



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 32/141 (22%), Positives = 71/141 (50%), Gaps = 7/141 (4%)

Query: 25   ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
            E + +LAQ+ QE     EA+ A    ++  ++RL+ E  DL+  +++  A   + +++ R
Sbjct: 1391 EAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQR 1450

Query: 81   DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            +F   +  ++Q  +E++  ++A  KE   L  E ++++   +E+ D    LR +      
Sbjct: 1451 NFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQ 1510

Query: 138  RMKELEAELAMAKQSLATLTK 158
             + +L  ++A   + +  L K
Sbjct: 1511 EISDLTEQIAEGGKQIHELEK 1531



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 42/188 (22%), Positives = 84/188 (44%), Gaps = 39/188 (20%)

Query: 2    KEMLAKDLEESQGGKS---SEVLSATELRVQLAQKEQEL-ARAKEA---LQAMKADRKRL 54
            K+ L + LE+ +   S   S++     + +QL +K +EL AR +E    ++A +A R + 
Sbjct: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135

Query: 55   KGEKTDLVSQMQQLYATLES--------------REEQLRDFIRNYEQHRKESEDAVKAL 100
            + +++DL  +++++   LE               RE + +   R+ E+   + E  V AL
Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAAL 1195

Query: 101  AKE------------------KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKEL 142
             K+                  K  LE+EK EL+ +  + + +A A+       +   + L
Sbjct: 1196 RKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL 1255

Query: 143  EAELAMAK 150
            E +++  K
Sbjct: 1256 EDQVSELK 1263



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 44/193 (22%), Positives = 86/193 (44%), Gaps = 13/193 (6%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            K  L  DL+ +Q           +L  +L +KE E++     ++  +A   +L+ +  +L
Sbjct: 1055 KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL 1114

Query: 62   VSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE- 113
             +++++L   +E+        E+Q  D  R  E+  +  E+A  A + + +L ++ + E 
Sbjct: 1115 QARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEF 1174

Query: 114  --LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE 171
              LRR  +EAT    A+ + L  K     +  AEL     +L  + + + K  S      
Sbjct: 1175 QKLRRDLEEATLQHEAMVAALRKKH---ADSMAELGEQIDNLQRVKQKLEKEKSELKMET 1231

Query: 172  TVLNGNQEWVVQA 184
              L+ N E + +A
Sbjct: 1232 DDLSSNAEAISKA 1244



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/176 (23%), Positives = 80/176 (45%), Gaps = 21/176 (11%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
            E L   LEE    K+     A    +Q ++ + +L R + E  Q  KA+ +R   +    
Sbjct: 1316 EELKHQLEEETKAKN-----ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSE 1370

Query: 62   VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            V+Q +  Y T    R E+L +  +   Q  +E+E+ V+A+  +   LE+ K  L+ + ++
Sbjct: 1371 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVED 1430

Query: 121  A---TDHATALRSQLDLKD-----------NRMKELEAELAMAKQSLATLTKDVPK 162
                 + + A  + LD K             + +E +AEL  +++   +L+ ++ K
Sbjct: 1431 LMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFK 1486



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 34/164 (20%), Positives = 79/164 (48%), Gaps = 18/164 (10%)

Query: 4    MLAKDLEESQGG-------KSSEVLSATELRVQLAQKEQ-ELARAKEALQAMKADRKRLK 55
            M+A++L++ Q         K +   +  +L+ +L + EQ  L   K+ +Q ++A  + L+
Sbjct: 1767 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1826

Query: 56   GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL- 114
            GE  +   +  +    L   E ++++     E+ RK        + + +DL+++ + ++ 
Sbjct: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN-------VLRLQDLVDKLQAKVK 1879

Query: 115  --RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
              +RQA+EA + + A  S+     + ++E E    +A+  +  L
Sbjct: 1880 SYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKL 1923



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 25/132 (18%), Positives = 56/132 (42%), Gaps = 7/132 (5%)

Query: 27   RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
            ++QL  K +E+    E  + + A+    +++L+ E ++L   +  L  TL   E  +   
Sbjct: 915  KIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 974

Query: 80   RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
             + ++N  +     ++ +  L+KEK  L+    +     +   D    L       + ++
Sbjct: 975  ENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQV 1034

Query: 140  KELEAELAMAKQ 151
             +LE  L   K+
Sbjct: 1035 DDLEGSLEQEKK 1046



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 32/179 (17%), Positives = 70/179 (39%), Gaps = 14/179 (7%)

Query: 1    MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            M   L K   +S      ++ +   ++ +L +++ EL    + L +      + KG    
Sbjct: 1191 MVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEK 1250

Query: 61   LVSQMQQLYATLESREEQLRDFIRN--------------YEQHRKESEDAVKALAKEKDL 106
            +   ++   + L+++EE+ +  I +              Y +   E +  V  L++ K  
Sbjct: 1251 MCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQA 1310

Query: 107  LEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
              ++  EL+ Q +E T    AL   L    +    L  +    ++  A L + + K +S
Sbjct: 1311 STQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
           sapiens]
          Length = 1939

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 17/161 (10%)

Query: 16  KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
           K   +L + E   ++A  ++E  + KE L   +A RK L+        EK DL  Q+Q  
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 69  YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
             +L   EE+    I+   Q          R E E+ + A L  +K  LE E  EL++  
Sbjct: 899 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958

Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
            +       +  +    +N++K L  E+A   +++A LTK+
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 999



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 39/184 (21%), Positives = 87/184 (47%), Gaps = 25/184 (13%)

Query: 25   ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
            E + +LAQ+ Q+     EA+ A    ++  ++RL+ E  DL+  +++  A   + +++ R
Sbjct: 1392 EAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQR 1451

Query: 81   DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            +F   +  ++Q  +E+   ++A  KE   L  E ++++   +E+ D       QL+    
Sbjct: 1452 NFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD-------QLETLKR 1504

Query: 138  RMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 197
              K L+ E++   + +A   K + +   +           ++ V Q    L AA+ +++ 
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKRIHELEKI-----------KKQVEQEKSELQAALEEAEA 1553

Query: 198  TLYH 201
            +L H
Sbjct: 1554 SLEH 1557



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 29/166 (17%)

Query: 7    KDLEESQGGKSSEVLSATELRVQLAQKEQELA----RAKEALQAMKADRKRLKGEKTDLV 62
            K  E    G  S++     L +QL +K +EL       +E ++A +A R + + +++DL 
Sbjct: 1085 KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144

Query: 63   SQMQQLYATLES--------------REEQLRDFIRNYE----QH-------RKESEDAV 97
             +++++   LE               RE + +   R+ E    QH       RK+  D+V
Sbjct: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1204

Query: 98   KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
              L ++ D L+R K +L ++  E       L S ++        LE
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLE 1250



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 10/148 (6%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
            E L + LEE    KS     A    +Q ++ + +L R + E  Q  KA+ +R   +    
Sbjct: 1317 EELKRQLEEEIKAKS-----ALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSE 1371

Query: 62   VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            V+Q +  Y T    R E+L +  +   Q  +++E+ V+A+  +   LE+ K  L+ + ++
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVED 1431

Query: 121  A---TDHATALRSQLDLKDNRMKELEAE 145
                 +   A  + LD K     ++ AE
Sbjct: 1432 LMIDVERTNAACAALDKKQRNFDKILAE 1459



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 15/158 (9%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            +LE SQ  K S  LS    +++ A +E     + + L+ +K + K L+ E +DL  Q+  
Sbjct: 1470 ELEASQ--KESRSLSTELFKIKNAYEE-----SLDQLETLKRENKNLQQEISDLTEQI-- 1520

Query: 68   LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATA 127
              A    R  +L    +  EQ + E +    AL + +  LE E+ ++ R   E     + 
Sbjct: 1521 --AEGGKRIHELEKIKKQVEQEKSELQ---AALEEAEASLEHEEGKILRIQLELNQVKSE 1575

Query: 128  LRSQLDLKDNRMKELEA-ELAMAKQSLATLTKDVPKRH 164
            +  ++  KD  + +++   + + +   +TL  ++  R+
Sbjct: 1576 VDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRN 1613



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 25/184 (13%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            K  L  DL+ +Q           +L  +L +KE E++  +  ++  +A   +L+ +  +L
Sbjct: 1056 KRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKEL 1115

Query: 62   VSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDL---LEREK 111
             +++++L   +E+        E+Q  D  R  E+  +  E+A  A + + ++    E E 
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1175

Query: 112  WELRRQAKEAT---------------DHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
             ++RR  +EAT               D    L  Q+D      ++LE E +  K  +  L
Sbjct: 1176 QKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235

Query: 157  TKDV 160
              ++
Sbjct: 1236 ASNM 1239



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 28/136 (20%), Positives = 59/136 (43%), Gaps = 5/136 (3%)

Query: 21   LSATELRVQLAQKE-QELARAKEALQA-MKADRKRLKGEKTDLVSQMQQLYATL---ESR 75
            L  T+++++   KE  E A  +E + A + A +++L+ E ++L   +  L  TL   E  
Sbjct: 912  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 971

Query: 76   EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLK 135
            +    + ++N  +     ++ +  L KEK  L+    +     +   D    L       
Sbjct: 972  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1031

Query: 136  DNRMKELEAELAMAKQ 151
            + ++ +LE  L   K+
Sbjct: 1032 EQQVDDLEGSLEQEKK 1047



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 37/197 (18%), Positives = 79/197 (40%), Gaps = 36/197 (18%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELR------VQLAQKEQELARAKEALQAMKADRK---- 52
            + + +DLEE+      E  +AT  +       +L ++   L R K+ L+  K++ K    
Sbjct: 1176 QKMRRDLEEAT--LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233

Query: 53   ----------RLKGEKTDLVSQMQQLYATLESREEQLRDFIRN--------------YEQ 88
                      + KG    +   ++   + ++++EE+ +  I +              Y +
Sbjct: 1234 DLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSR 1293

Query: 89   HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM 148
               E +  V  L++ K    ++  EL+RQ +E     +AL   L    +    L  +   
Sbjct: 1294 QLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353

Query: 149  AKQSLATLTKDVPKRHS 165
             +++ A L + + K +S
Sbjct: 1354 EQEAKAELQRAMSKANS 1370


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/165 (24%), Positives = 81/165 (49%), Gaps = 9/165 (5%)

Query: 7   KDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL---V 62
           KD+ E +  K + +    E L+ QL  K+++L   K+ +++++ D          L   +
Sbjct: 531 KDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAL 590

Query: 63  SQMQQLYATL-ESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
           S+ +++   L E RE   R+ +   E  RKE++D    L ++ + L+ E  E      + 
Sbjct: 591 SEKERIIERLKEQRERDDRERLEEIESFRKENKD----LKEKVNALQAELTEKESSLIDL 646

Query: 122 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSL 166
            +HA++L S    +D+++K LE  +   K+  + L   + K H++
Sbjct: 647 KEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNI 691



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 40/171 (23%), Positives = 82/171 (47%), Gaps = 23/171 (13%)

Query: 26  LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ-------LYATLESREEQ 78
           LR++L +KE  L +  + LQ +  ++  L GE  D+   ++        L   +E+ +EQ
Sbjct: 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554

Query: 79  LRDF----------IRNYEQHRKESEDAV----KALAKEKDLLEREKWELRRQAKEATDH 124
           LRD           +++ +     ++ A+    +AL++++ ++ER K +  R  +E  + 
Sbjct: 555 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEE 614

Query: 125 ATALRSQ-LDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVL 174
             + R +  DLK+ ++  L+AEL   + SL  L +      S  +  ++ L
Sbjct: 615 IESFRKENKDLKE-KVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKL 664



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 39/173 (22%), Positives = 77/173 (44%), Gaps = 22/173 (12%)

Query: 9   LEESQGGKSSE--VLSATELRVQLAQKE-----QELARAKEALQAMKADRKRLKGEKTDL 61
           L++  G + +E   +  TE   +  Q E     +EL   ++ L+ M+   +  K      
Sbjct: 242 LQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNAR 301

Query: 62  VSQMQQLYATLESREEQLRDFIRNYEQHRK--ESEDAVKALA-----KEKDLLE-REKWE 113
              +++L   L+S+    +    + E+ R+  E+E  V  L      KEK+ +  RE+  
Sbjct: 302 DESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH 361

Query: 114 LRRQAKEATDHATALRSQLDLKDNR-------MKELEAELAMAKQSLATLTKD 159
            R Q +       AL++ +++KD +       +++LE E+ M K +    T+D
Sbjct: 362 RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTED 414



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 25/121 (20%), Positives = 50/121 (41%), Gaps = 2/121 (1%)

Query: 26  LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDF--I 83
           L+ +L +KE  L   KE   ++ +   +   +   L   ++Q        E QL+    I
Sbjct: 632 LQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNI 691

Query: 84  RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
            +  +   E  D +K L KE      E  + + +     +    + ++ + KD ++ ELE
Sbjct: 692 EDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE 751

Query: 144 A 144
           +
Sbjct: 752 S 752


>gi|92091575 coiled-coil domain containing 57 [Homo sapiens]
          Length = 915

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 53/212 (25%), Positives = 90/212 (42%), Gaps = 26/212 (12%)

Query: 13  QGGKSSEVLSATELRVQLAQKEQEL-----ARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
           Q    S    + EL+V+L  KE E      A+A E+LQ  +A    L+ +      ++Q 
Sbjct: 192 QADNMSNTALSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELERKLQSRAGELQD 251

Query: 68  LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK---------------W 112
           L A   +R + L D + + +  RK+ E+  K   +E D L REK                
Sbjct: 252 LEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLVAVKGAHVEQLQ 311

Query: 113 ELRRQAKEATDHATALRSQLDLKDNRM----KELEAELAMAKQSLATLTKDVPKRHSLAM 168
           EL+ +  E   H   L +QL   + R     KE +A +   ++  +T+ K         +
Sbjct: 312 ELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAIDQLREDASTV-KSAWDAQIAQL 370

Query: 169 PGETVLNGNQ-EWVVQADLPLTAAIRQSQQTL 199
             E V    Q + + + ++ L A + +SQQ +
Sbjct: 371 SKEMVSRDLQIQTLQEEEVKLKAQVARSQQDI 402



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 28/133 (21%)

Query: 25  ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
           E  ++L + +   A+A+E  +A +A+   LK E   L   + +    +E  ++Q +    
Sbjct: 66  ERDLELERYDAAFAQAREWEEARRAEVSELKIEAAKLRQALAREARKVEELQQQQQ---L 122

Query: 85  NYEQHRKESE----DAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK 140
            +++HR E E    D    +   ++  E  KW L R                     +++
Sbjct: 123 AFQEHRLELERVHSDKNGEIDHHREQYENLKWTLER---------------------KLE 161

Query: 141 ELEAELAMAKQSL 153
           EL+ ELA+ +Q L
Sbjct: 162 ELDGELALQRQEL 174


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
           sapiens]
          Length = 1939

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 43/161 (26%), Positives = 71/161 (44%), Gaps = 17/161 (10%)

Query: 16  KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
           K   +L + E   ++A  ++E  + KE L   +A RK L+        EK DL  Q+Q  
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 69  YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
              L   EE+    I+   Q          R E E+ + A L  +K  LE E  EL++  
Sbjct: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958

Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
            +       +  +    +N++K L  E+A   +++A LTK+
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 999



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 30/141 (21%), Positives = 72/141 (51%), Gaps = 7/141 (4%)

Query: 25   ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
            E + +LAQ+ Q+     EA+ +    ++  ++RL+ E  DL+  +++  A   + +++ R
Sbjct: 1392 EAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQR 1451

Query: 81   DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            +F   +  ++Q  +E++  ++A  KE   L  E ++++   +E+ DH   L+ +      
Sbjct: 1452 NFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQ 1511

Query: 138  RMKELEAELAMAKQSLATLTK 158
             + +L  ++A   + +  L K
Sbjct: 1512 EISDLTEQIAEGGKHIHELEK 1532



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 35/175 (20%), Positives = 75/175 (42%), Gaps = 32/175 (18%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            ++   QG    E   A +L+ ++ + +  +   +E ++A +A R + + +++DL  ++++
Sbjct: 1090 EMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149

Query: 68   LYATLES--------------REEQLRDFIRNYE----QH-------RKESEDAVKALAK 102
            +   LE               RE + +   R+ E    QH       RK+  D+V  L +
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGE 1209

Query: 103  E-------KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAK 150
            +       K  LE+EK EL+ +  +   +   +       +   + LE +L+  K
Sbjct: 1210 QIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIK 1264



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 10/158 (6%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            + + +DLEES         +A  LR + A    EL    ++LQ +K   ++L+ EK++L 
Sbjct: 1176 QKMRRDLEEST---LQHEATAAALRKKHADSVAELGEQIDSLQRVK---QKLEKEKSELK 1229

Query: 63   SQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEAT 122
             ++  L + +E+  +       N+E+  +  ED +  +  +++  +R   EL  Q     
Sbjct: 1230 MEINDLASNMETVSKAKA----NFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLH 1285

Query: 123  DHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
              +     QLD KD  + +L        Q +  L + +
Sbjct: 1286 TESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 10/148 (6%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
            E L + LEE    KS+   +     +Q A+ + +L R + E  Q  KA+ +R   +    
Sbjct: 1317 EELKRQLEEETKAKSTLAHA-----LQSARHDCDLLREQYEEEQEAKAELQRGMSKANSE 1371

Query: 62   VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            V+Q +  Y T    R E+L +  +   Q  +++E+ V+A+  +   LE+ K  L+ + ++
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVED 1431

Query: 121  A---TDHATALRSQLDLKDNRMKELEAE 145
                 + + A    LD K     ++ AE
Sbjct: 1432 LMIDVERSNAACIALDKKQRNFDKVLAE 1459



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 8/138 (5%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            +LE SQ  K S  LS    +V+ A +E     + + L+ +K + K L+ E +DL  Q+ +
Sbjct: 1470 ELEASQ--KESRSLSTELFKVKNAYEE-----SLDHLETLKRENKNLQQEISDLTEQIAE 1522

Query: 68   LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATA 127
                +   E+  +       + +   E+A  +L  E+  + R + EL +   E       
Sbjct: 1523 GGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAE 1582

Query: 128  LRSQLD-LKDNRMKELEA 144
               +LD LK N ++ +E+
Sbjct: 1583 KDEELDQLKRNHLRVVES 1600



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 38/184 (20%), Positives = 79/184 (42%), Gaps = 25/184 (13%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            K  L  DL+ +Q           +L  +L +KE E++  +  ++  +A   +L+ +  +L
Sbjct: 1056 KRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKEL 1115

Query: 62   VSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDL---LEREK 111
             +++++L   +E+        E+Q  D  R  E+  +  E+A  A + + ++    E E 
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1175

Query: 112  WELRRQAKEAT---------------DHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
             ++RR  +E+T               D    L  Q+D      ++LE E +  K  +  L
Sbjct: 1176 QKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDL 1235

Query: 157  TKDV 160
              ++
Sbjct: 1236 ASNM 1239



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 28/136 (20%), Positives = 59/136 (43%), Gaps = 5/136 (3%)

Query: 21   LSATELRVQLAQKE-QELARAKEALQA-MKADRKRLKGEKTDLVSQMQQLYATL---ESR 75
            L  T+++++   KE  E A  +E + A + A +++L+ E ++L   +  L  TL   E  
Sbjct: 912  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 971

Query: 76   EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLK 135
            +    + ++N  +     ++ +  L KEK  L+    +     +   D    L       
Sbjct: 972  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKL 1031

Query: 136  DNRMKELEAELAMAKQ 151
            + ++ +LE  L   K+
Sbjct: 1032 EQQVDDLEGSLEQEKK 1047



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 20/172 (11%)

Query: 5    LAKDLEESQGGKSSEVLSATELRVQLAQ---KEQELARAKEALQAMKA-------DRKRL 54
            LA ++E     K++       L  QL++   KE+E  R    L A KA       +  R 
Sbjct: 1235 LASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQ 1294

Query: 55   KGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLERE---- 110
              EK  +VSQ+ +       + E+L+  +    + +     A+++   + DLL  +    
Sbjct: 1295 LDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEE 1354

Query: 111  ---KWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
               K EL+R   +A       R++ +    +  E   EL  AK+ LA   +D
Sbjct: 1355 QEAKAELQRGMSKANSEVAQWRTKYETDAIQRTE---ELEEAKKKLAQRLQD 1403


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 18/175 (10%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKT-- 59
            ++ L K   + +G  +       EL+ Q+A+ + +LA+ +E LQA  A  +    +K   
Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMA 1102

Query: 60   -----DLVSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
                 +L SQ+ +L   LES        E+Q RD     E  + E ED + + A +++L 
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162

Query: 108  EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
             + + E+    +   +EA  H   ++         ++EL  +L   K+  A L K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK 1217



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 5/166 (3%)

Query: 10   EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
            EE +  KS   L   +    +   E+ L R ++  Q ++  R++L+G+ TDL  Q+ +L 
Sbjct: 1010 EEEEKSKSLAKLK-NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQ 1068

Query: 70   ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
            A +   + QL       E+  + +   V+  A +K++  ++  EL  Q  E  +   + R
Sbjct: 1069 AQIAELKMQL----AKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124

Query: 130  SQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLN 175
            +  +  + + ++L  EL   K  L         +  L    E  +N
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 14/164 (8%)

Query: 9    LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKR----LKGEKTDLVSQ 64
            L+E    ++     A ELR +L  K+QEL      L+A   + +     L+ EK  +   
Sbjct: 885  LQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQN 944

Query: 65   MQQLYATLESREEQLRDF----------IRNYEQHRKESEDAVKALAKEKDLLEREKWEL 114
            +Q+L   LE  E   +            ++  E+ +   ED    LAKEK LLE    E 
Sbjct: 945  IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004

Query: 115  RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
                 E  + + +L    +  +  + +LE  L   ++    L K
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEK 1048



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 6/140 (4%)

Query: 2    KEMLAKDLEESQGG-KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            KE+  K L+E +G  KS    S T L  ++AQ E++L    +  QA     +R + +  D
Sbjct: 1788 KELKVK-LQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846

Query: 61   LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            ++ Q+       E  ++Q        +Q +++ E+A     +E       + +L+R+ ++
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA----EEEAQRANASRRKLQRELED 1902

Query: 121  ATDHATALRSQLDLKDNRMK 140
            AT+ A A+  ++    N+++
Sbjct: 1903 ATETADAMNREVSSLKNKLR 1922



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 38/181 (20%), Positives = 74/181 (40%), Gaps = 35/181 (19%)

Query: 1    MKEMLAKDLEESQGGKSSEVLSATELRVQLA---QKEQELARAKEALQAMKADRKRLKGE 57
            +K  LAK  EE Q   +     A +  + L    + E +++  +E L++ +A R + + +
Sbjct: 1074 LKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQ 1133

Query: 58   KTDLVSQMQQLYATLESR-------------------------EEQLRDFIRNYEQHRKE 92
            K DL  +++ L   LE                           EE+ +      ++ R++
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193

Query: 93   SEDAVKALAKE-------KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAE 145
               AV+ LA++       K  LE+ K  L  +  E  +    L       +++ K++EA+
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQ 1253

Query: 146  L 146
            L
Sbjct: 1254 L 1254



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 24/156 (15%)

Query: 4    MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVS 63
            +L K LEE      +++    E+R + +Q  +ELA   E  + +KA+ ++ K        
Sbjct: 1171 ILKKTLEEEAKTHEAQI---QEMRQKHSQAVEELAEQLEQTKRVKANLEKAK-------- 1219

Query: 64   QMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATD 123
                   TLE+   +L + ++   Q + +SE   K +  +   L+ +  E  R   E  D
Sbjct: 1220 ------QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD 1273

Query: 124  HATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
              T L+ +LD        +   L+ +    + LTKD
Sbjct: 1274 KVTKLQVELD-------NVTGLLSQSDSKSSKLTKD 1302



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 40/177 (22%), Positives = 71/177 (40%), Gaps = 27/177 (15%)

Query: 1    MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            MK    +DL   QG          +L  Q+ + E EL   ++      A RK+L+ +  D
Sbjct: 1565 MKAQFERDL---QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKD 1621

Query: 61   L--------------VSQMQQLYATLESREEQLRDFIRNYEQ---HRKESEDAVKA---- 99
            L              + Q+++L A ++    +L D   + E+     KE+E  +K+    
Sbjct: 1622 LEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAE 1681

Query: 100  ---LAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
               L +E    ER K + +++  E  D       +  L     + LEA +A  ++ L
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEEL 1738



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 36/167 (21%), Positives = 71/167 (42%), Gaps = 7/167 (4%)

Query: 11   ESQGGKSSEVLSATELRVQLAQKE-QELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
            +S+  K ++  SA E ++Q  Q+  QE  R K +L       K+++ EK     Q+++  
Sbjct: 1293 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL---KQVEDEKNSFREQLEEEE 1349

Query: 70   ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
                + E+Q+          +K+ ED+V  L   +++  + + +L   ++   +   A  
Sbjct: 1350 EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYD 1409

Query: 130  SQLDLKDNRMKELE---AELAMAKQSLATLTKDVPKRHSLAMPGETV 173
                 K    +EL+    +L   +QS   L K   K   L    +T+
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI 1456



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 34/180 (18%), Positives = 76/180 (42%), Gaps = 23/180 (12%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E   + LE  +G  ++EV    + +     K +++    + LQ    + +R++ E  D V
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 1275

Query: 63   SQMQ---------------------QLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 101
            +++Q                     + ++ LES+ +  ++ ++   + +      +K + 
Sbjct: 1276 TKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVE 1335

Query: 102  KEKDLLEREKWELRRQAKEATDHATA-LRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
             EK+   RE+ E   +AK   +   A L +Q+     +M++    L  A++    L KD+
Sbjct: 1336 DEKNSF-REQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL 1394


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +EM AK+ +E Q  K  +  +  EL+ +L QK  +L   K  LQ      ++L+ E T+L
Sbjct: 852  EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 902

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
             ++ +++   L +++++L + +   E   +E ED  + L  E+  + ++  +L  Q +E 
Sbjct: 903  YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962

Query: 122  TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
                  L+ +    + ++K+LE E+ +       L+K+
Sbjct: 963  EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            KE LA++L  S  G+++       L  ++AQ E+EL   +  ++AM    ++   +   L
Sbjct: 1710 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
             +++    +T +  E   +   R  ++ R    E E AVK+  K     LE +  +L  Q
Sbjct: 1770 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829

Query: 118  AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
             ++      A    L  KD ++KE+    E E  MA+Q
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
            ++ L K   + +G  S       +L+ Q+A+ + +LA+ +E LQA  A            
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1109

Query: 50   --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
                + L+G  +DL   +    A     E+Q RD     E  + E ED + + A +++L 
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169

Query: 108  EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
             + + E+    +   +E   H   ++         ++EL  +L   K++ A L K+
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)

Query: 25   ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
            +L+ QL + E EL   ++      A +K+L+G+  DL       +   ++    L   + 
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1652

Query: 78   QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            Q++DF R  E  R  S D + A AKE +   +       Q +E    A   R Q DL+  
Sbjct: 1653 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1709

Query: 138  RMKELEAELA 147
              +EL  ELA
Sbjct: 1710 -KEELAEELA 1718



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +  L   L+E    K +     + L +QL+  +++L      ++A++  +KR + E  +L
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404

Query: 62   VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
              Q ++  A  +  E       ++L D + + +  R       K+     + LA+EK   
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464

Query: 105  ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
                D  +R + E R +  +A   A AL   L+ K+    ELE    M K  +  L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1516



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            DLEE       E  +  +L+++    E ++ + ++ +  M     +L  E+  L  ++  
Sbjct: 954  DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010

Query: 68   LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
            L   L   EE+ ++  +   +H     E E  +K   K +  LE+ K +L   A +  + 
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070

Query: 125  ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
               L++Q+     ++ + E EL  A   LA L  ++ ++++
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1108



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
            E  AK LE        ++ +A   R Q   +KE+   ELA +     A++ +++RL+   
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738

Query: 59   TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
              L  ++++    +E+  +++R   +  EQ    +E A +    +K+  E  + +L RQ 
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1794

Query: 119  KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
            KE       LRS+L   +  +K + ++ +A  +  +A L + V
Sbjct: 1795 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)

Query: 2    KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            KE+ +K L E +G   S+  S    L  ++AQ E+++ +     QA     K+   +  +
Sbjct: 1795 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853

Query: 61   LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            ++ Q++      E  +EQ        +Q +++ E+A     +E   +   + +L+R+  E
Sbjct: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1909

Query: 121  ATDHATALRSQLDLKDNRMK 140
            AT+   A+  +++   ++++
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E L + LE+ +  K++   +   L  + A    EL    +A Q ++  +K+L+ +  +L 
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265

Query: 63   SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
            S+    ++  A L  +  +L++ + +      E+E     LAK+   L  +  +    L+
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325

Query: 116  RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
             + ++  + +T LR QL+ + N +++   E   AKQ+L
Sbjct: 1326 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1362



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)

Query: 9   LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
           LEE +  K ++V+ A +   +     +  A+ ++ L AMK  ++                
Sbjct: 778 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 837

Query: 57  -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
             K   + Q+ +    ++++E++L   ++  +  E   KE E     L +EK+LL     
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897

Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
                  E E+  +R  AK  E  +    + ++L+ +++R ++L+AE     Q +  L +
Sbjct: 898 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 957

Query: 159 DVPKRHS 165
            + +  +
Sbjct: 958 QLEEEEA 964



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E    +L +      +EV S T +  +   K  +LA+   +L +   D + L  E+T   
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331

Query: 63   SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
              +      LE     L+D +       +N E+H           +K+ +D    V+AL 
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391

Query: 102  KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
            + K   ++E   L +Q +E       L    +     + +L  +L   +Q ++ L K
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +EM AK+ +E Q  K  +  +  EL+ +L QK  +L   K  LQ      ++L+ E T+L
Sbjct: 859  EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 909

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
             ++ +++   L +++++L + +   E   +E ED  + L  E+  + ++  +L  Q +E 
Sbjct: 910  YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969

Query: 122  TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
                  L+ +    + ++K+LE E+ +       L+K+
Sbjct: 970  EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            KE LA++L  S  G+++       L  ++AQ E+EL   +  ++AM    ++   +   L
Sbjct: 1717 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
             +++    +T +  E   +   R  ++ R    E E AVK+  K     LE +  +L  Q
Sbjct: 1777 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836

Query: 118  AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
             ++      A    L  KD ++KE+    E E  MA+Q
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
            ++ L K   + +G  S       +L+ Q+A+ + +LA+ +E LQA  A            
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1116

Query: 50   --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
                + L+G  +DL   +    A     E+Q RD     E  + E ED + + A +++L 
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176

Query: 108  EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
             + + E+    +   +E   H   ++         ++EL  +L   K++ A L K+
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)

Query: 25   ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
            +L+ QL + E EL   ++      A +K+L+G+  DL       +   ++    L   + 
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1659

Query: 78   QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            Q++DF R  E  R  S D + A AKE +   +       Q +E    A   R Q DL+  
Sbjct: 1660 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1716

Query: 138  RMKELEAELA 147
              +EL  ELA
Sbjct: 1717 -KEELAEELA 1725



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +  L   L+E    K +     + L +QL+  +++L      ++A++  +KR + E  +L
Sbjct: 1352 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411

Query: 62   VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
              Q ++  A  +  E       ++L D + + +  R       K+     + LA+EK   
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471

Query: 105  ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
                D  +R + E R +  +A   A AL   L+ K+    ELE    M K  +  L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1523



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            DLEE       E  +  +L+++    E ++ + ++ +  M     +L  E+  L  ++  
Sbjct: 961  DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017

Query: 68   LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
            L   L   EE+ ++  +   +H     E E  +K   K +  LE+ K +L   A +  + 
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077

Query: 125  ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
               L++Q+     ++ + E EL  A   LA L  ++ ++++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1115



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
            E  AK LE        ++ +A   R Q   +KE+   ELA +     A++ +++RL+   
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745

Query: 59   TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
              L  ++++    +E+  +++R   +  EQ    +E A +    +K+  E  + +L RQ 
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1801

Query: 119  KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
            KE       LRS+L   +  +K + ++ +A  +  +A L + V
Sbjct: 1802 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)

Query: 2    KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            KE+ +K L E +G   S+  S    L  ++AQ E+++ +     QA     K+   +  +
Sbjct: 1802 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860

Query: 61   LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            ++ Q++      E  +EQ        +Q +++ E+A     +E   +   + +L+R+  E
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1916

Query: 121  ATDHATALRSQLDLKDNRMK 140
            AT+   A+  +++   ++++
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E L + LE+ +  K++   +   L  + A    EL    +A Q ++  +K+L+ +  +L 
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272

Query: 63   SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
            S+    ++  A L  +  +L++ + +      E+E     LAK+   L  +  +    L+
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332

Query: 116  RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
             + ++  + +T LR QL+ + N +++   E   AKQ+L
Sbjct: 1333 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1369



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)

Query: 9   LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
           LEE +  K ++V+ A +   +     +  A+ ++ L AMK  ++                
Sbjct: 785 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 844

Query: 57  -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
             K   + Q+ +    ++++E++L   ++  +  E   KE E     L +EK+LL     
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 904

Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
                  E E+  +R  AK  E  +    + ++L+ +++R ++L+AE     Q +  L +
Sbjct: 905 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 964

Query: 159 DVPKRHS 165
            + +  +
Sbjct: 965 QLEEEEA 971



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E    +L +      +EV S T +  +   K  +LA+   +L +   D + L  E+T   
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338

Query: 63   SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
              +      LE     L+D +       +N E+H           +K+ +D    V+AL 
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398

Query: 102  KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
            + K   ++E   L +Q +E       L    +     + +L  +L   +Q ++ L K
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +EM AK+ +E Q  K  +  +  EL+ +L QK  +L   K  LQ      ++L+ E T+L
Sbjct: 859  EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 909

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
             ++ +++   L +++++L + +   E   +E ED  + L  E+  + ++  +L  Q +E 
Sbjct: 910  YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969

Query: 122  TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
                  L+ +    + ++K+LE E+ +       L+K+
Sbjct: 970  EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            KE LA++L  S  G+++       L  ++AQ E+EL   +  ++AM    ++   +   L
Sbjct: 1717 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
             +++    +T +  E   +   R  ++ R    E E AVK+  K     LE +  +L  Q
Sbjct: 1777 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836

Query: 118  AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
             ++      A    L  KD ++KE+    E E  MA+Q
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
            ++ L K   + +G  S       +L+ Q+A+ + +LA+ +E LQA  A            
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1116

Query: 50   --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
                + L+G  +DL   +    A     E+Q RD     E  + E ED + + A +++L 
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176

Query: 108  EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
             + + E+    +   +E   H   ++         ++EL  +L   K++ A L K+
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)

Query: 25   ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
            +L+ QL + E EL   ++      A +K+L+G+  DL       +   ++    L   + 
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1659

Query: 78   QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            Q++DF R  E  R  S D + A AKE +   +       Q +E    A   R Q DL+  
Sbjct: 1660 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1716

Query: 138  RMKELEAELA 147
              +EL  ELA
Sbjct: 1717 -KEELAEELA 1725



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +  L   L+E    K +     + L +QL+  +++L      ++A++  +KR + E  +L
Sbjct: 1352 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411

Query: 62   VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
              Q ++  A  +  E       ++L D + + +  R       K+     + LA+EK   
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471

Query: 105  ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
                D  +R + E R +  +A   A AL   L+ K+    ELE    M K  +  L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1523



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            DLEE       E  +  +L+++    E ++ + ++ +  M     +L  E+  L  ++  
Sbjct: 961  DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017

Query: 68   LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
            L   L   EE+ ++  +   +H     E E  +K   K +  LE+ K +L   A +  + 
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077

Query: 125  ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
               L++Q+     ++ + E EL  A   LA L  ++ ++++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1115



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
            E  AK LE        ++ +A   R Q   +KE+   ELA +     A++ +++RL+   
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745

Query: 59   TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
              L  ++++    +E+  +++R   +  EQ    +E A +    +K+  E  + +L RQ 
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1801

Query: 119  KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
            KE       LRS+L   +  +K + ++ +A  +  +A L + V
Sbjct: 1802 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)

Query: 2    KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            KE+ +K L E +G   S+  S    L  ++AQ E+++ +     QA     K+   +  +
Sbjct: 1802 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860

Query: 61   LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            ++ Q++      E  +EQ        +Q +++ E+A     +E   +   + +L+R+  E
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1916

Query: 121  ATDHATALRSQLDLKDNRMK 140
            AT+   A+  +++   ++++
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E L + LE+ +  K++   +   L  + A    EL    +A Q ++  +K+L+ +  +L 
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272

Query: 63   SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
            S+    ++  A L  +  +L++ + +      E+E     LAK+   L  +  +    L+
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332

Query: 116  RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
             + ++  + +T LR QL+ + N +++   E   AKQ+L
Sbjct: 1333 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1369



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)

Query: 9   LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
           LEE +  K ++V+ A +   +     +  A+ ++ L AMK  ++                
Sbjct: 785 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 844

Query: 57  -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
             K   + Q+ +    ++++E++L   ++  +  E   KE E     L +EK+LL     
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 904

Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
                  E E+  +R  AK  E  +    + ++L+ +++R ++L+AE     Q +  L +
Sbjct: 905 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 964

Query: 159 DVPKRHS 165
            + +  +
Sbjct: 965 QLEEEEA 971



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E    +L +      +EV S T +  +   K  +LA+   +L +   D + L  E+T   
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338

Query: 63   SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
              +      LE     L+D +       +N E+H           +K+ +D    V+AL 
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398

Query: 102  KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
            + K   ++E   L +Q +E       L    +     + +L  +L   +Q ++ L K
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +EM AK+ +E Q  K  +  +  EL+ +L QK  +L   K  LQ      ++L+ E T+L
Sbjct: 852  EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 902

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
             ++ +++   L +++++L + +   E   +E ED  + L  E+  + ++  +L  Q +E 
Sbjct: 903  YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962

Query: 122  TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
                  L+ +    + ++K+LE E+ +       L+K+
Sbjct: 963  EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            KE LA++L  S  G+++       L  ++AQ E+EL   +  ++AM    ++   +   L
Sbjct: 1710 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
             +++    +T +  E   +   R  ++ R    E E AVK+  K     LE +  +L  Q
Sbjct: 1770 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829

Query: 118  AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
             ++      A    L  KD ++KE+    E E  MA+Q
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
            ++ L K   + +G  S       +L+ Q+A+ + +LA+ +E LQA  A            
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1109

Query: 50   --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
                + L+G  +DL   +    A     E+Q RD     E  + E ED + + A +++L 
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169

Query: 108  EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
             + + E+    +   +E   H   ++         ++EL  +L   K++ A L K+
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)

Query: 25   ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
            +L+ QL + E EL   ++      A +K+L+G+  DL       +   ++    L   + 
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1652

Query: 78   QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            Q++DF R  E  R  S D + A AKE +   +       Q +E    A   R Q DL+  
Sbjct: 1653 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1709

Query: 138  RMKELEAELA 147
              +EL  ELA
Sbjct: 1710 -KEELAEELA 1718



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +  L   L+E    K +     + L +QL+  +++L      ++A++  +KR + E  +L
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404

Query: 62   VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
              Q ++  A  +  E       ++L D + + +  R       K+     + LA+EK   
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464

Query: 105  ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
                D  +R + E R +  +A   A AL   L+ K+    ELE    M K  +  L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1516



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            DLEE       E  +  +L+++    E ++ + ++ +  M     +L  E+  L  ++  
Sbjct: 954  DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010

Query: 68   LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
            L   L   EE+ ++  +   +H     E E  +K   K +  LE+ K +L   A +  + 
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070

Query: 125  ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
               L++Q+     ++ + E EL  A   LA L  ++ ++++
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1108



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
            E  AK LE        ++ +A   R Q   +KE+   ELA +     A++ +++RL+   
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738

Query: 59   TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
              L  ++++    +E+  +++R   +  EQ    +E A +    +K+  E  + +L RQ 
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1794

Query: 119  KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
            KE       LRS+L   +  +K + ++ +A  +  +A L + V
Sbjct: 1795 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)

Query: 2    KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            KE+ +K L E +G   S+  S    L  ++AQ E+++ +     QA     K+   +  +
Sbjct: 1795 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853

Query: 61   LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
            ++ Q++      E  +EQ        +Q +++ E+A     +E   +   + +L+R+  E
Sbjct: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1909

Query: 121  ATDHATALRSQLDLKDNRMK 140
            AT+   A+  +++   ++++
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E L + LE+ +  K++   +   L  + A    EL    +A Q ++  +K+L+ +  +L 
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265

Query: 63   SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
            S+    ++  A L  +  +L++ + +      E+E     LAK+   L  +  +    L+
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325

Query: 116  RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
             + ++  + +T LR QL+ + N +++   E   AKQ+L
Sbjct: 1326 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1362



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)

Query: 9   LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
           LEE +  K ++V+ A +   +     +  A+ ++ L AMK  ++                
Sbjct: 778 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 837

Query: 57  -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
             K   + Q+ +    ++++E++L   ++  +  E   KE E     L +EK+LL     
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897

Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
                  E E+  +R  AK  E  +    + ++L+ +++R ++L+AE     Q +  L +
Sbjct: 898 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 957

Query: 159 DVPKRHS 165
            + +  +
Sbjct: 958 QLEEEEA 964



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
            E    +L +      +EV S T +  +   K  +LA+   +L +   D + L  E+T   
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331

Query: 63   SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
              +      LE     L+D +       +N E+H           +K+ +D    V+AL 
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391

Query: 102  KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
            + K   ++E   L +Q +E       L    +     + +L  +L   +Q ++ L K
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 39/146 (26%), Positives = 72/146 (49%), Gaps = 5/146 (3%)

Query: 16  KSSEV-LSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLES 74
           KSSEV      L+ + AQ ++ L +++   + +KA +  L  EK DL+ Q+Q    TL +
Sbjct: 853 KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912

Query: 75  REEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDL 134
            EEQ    I++    + + E  VK L++  +  E    EL  + ++  D    L+ ++D 
Sbjct: 913 VEEQCEWLIKS----KIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDD 968

Query: 135 KDNRMKELEAELAMAKQSLATLTKDV 160
            +  + + E E    +  +  LT++V
Sbjct: 969 LETMLVKSEKEKRTTEHKVKNLTEEV 994



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 35/171 (20%), Positives = 81/171 (47%), Gaps = 13/171 (7%)

Query: 5    LAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQ 64
            + K+ EE      +    A +  ++ A   +EL + ++ +  ++  R+ ++   TDL  +
Sbjct: 1749 MQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKR 1808

Query: 65   MQQL--YATLESR------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR 116
            + +    A + SR      E ++R+     E   + S +A +   +    LER   EL  
Sbjct: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARR----LERCIKELTY 1864

Query: 117  QAKEATDHATALRSQLDLKDNRMKELEAELAMAK-QSLATLTKDVPKRHSL 166
            QA+E   + + +++Q+D    +++  + ++ +A+ Q+   L+K   ++H L
Sbjct: 1865 QAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHEL 1915



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 13/133 (9%)

Query: 1    MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
            +K+ L KD       KS   L   +L  ++ Q  +  A A E L  +  +R      K D
Sbjct: 1225 VKQKLEKD-------KSDLQLEVDDLLTRVEQMTRAKANA-EKLCTLYEERLHEATAKLD 1276

Query: 61   LVSQMQQLYATLESRE-EQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAK 119
             V+Q+    A  +++   +  +F+R  E    E E  +  L++EK    R+  +LR Q +
Sbjct: 1277 KVTQLANDLAAQKTKLWSESGEFLRRLE----EKEALINQLSREKSNFTRQIEDLRGQLE 1332

Query: 120  EATDHATALRSQL 132
            + T   +AL   L
Sbjct: 1333 KETKSQSALAHAL 1345



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 39/168 (23%), Positives = 64/168 (38%), Gaps = 21/168 (12%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            KE L   L      KS+      +LR QL ++ +  +    ALQ  + D   L+ +  + 
Sbjct: 1306 KEALINQLSRE---KSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEE 1362

Query: 62   VSQMQQLYATLESREEQLRDFIRNYE----QHRKESEDAVKALA--------------KE 103
                 +L+ TL     ++  +   YE    Q  ++ EDA K LA                
Sbjct: 1363 QEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANAR 1422

Query: 104  KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 151
               LER + +L+ +  +A      +RS     D +  +    LA  KQ
Sbjct: 1423 NASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 30/145 (20%), Positives = 64/145 (44%), Gaps = 15/145 (10%)

Query: 16   KSSEVLSATELRVQLAQKE-QELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLES 74
            K  E L+  EL++  A ++  E  ++   LQ    D +    + T L S +++  A  E 
Sbjct: 1629 KMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAER 1688

Query: 75   REEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDL 134
            R   L+  + +    ++++E   +    E++LLE            AT+      +Q   
Sbjct: 1689 RNSLLQSELEDLRSLQEQTERGRRL--SEEELLE------------ATERINLFYTQNTS 1734

Query: 135  KDNRMKELEAELAMAKQSLATLTKD 159
              ++ K+LEA++A  ++    + ++
Sbjct: 1735 LLSQKKKLEADVARMQKEAEEVVQE 1759


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 41/170 (24%), Positives = 75/170 (44%), Gaps = 19/170 (11%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            KE L K+    Q   S +    T+L+ +L++    +   KE L+  K +   L  + TDL
Sbjct: 1320 KEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDL 1379

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK---------- 111
              Q+Q    +L  +E  +    + Y++ + E  D V+ L+ + D L +EK          
Sbjct: 1380 NVQLQN-SISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDW 1438

Query: 112  ------WELRRQAKEATDHATA--LRSQLDLKDNRMKELEAELAMAKQSL 153
                  W+ + Q++      T   L+ QL+LK     E + ++ + K+ L
Sbjct: 1439 SNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEEL 1488



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 10/136 (7%)

Query: 28   VQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRD---FIR 84
            +QL +KEQE+A  K+ +     +++ +  E T L  +  +   TL   +EQL+     + 
Sbjct: 1064 IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVN 1123

Query: 85   NYEQ-------HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            +  Q       H ++ E  +    KE   L+ +  EL+  A+E     + L S+L   D 
Sbjct: 1124 SLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDE 1183

Query: 138  RMKELEAELAMAKQSL 153
              + L++    + +SL
Sbjct: 1184 EFQSLKSSHEKSNKSL 1199



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 33/143 (23%), Positives = 65/143 (45%), Gaps = 10/143 (6%)

Query: 25   ELRVQLAQKEQELARAKEALQAMKAD----RKR---LKGEKTDLVSQMQQLYATLESREE 77
            EL++QL  K +E     E +  +K +     KR   LKGE  D  S+M++  + LE+  +
Sbjct: 1462 ELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELK 1521

Query: 78   QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
                 I   E H  +    +++L    ++L+    +   + KE        +   + KDN
Sbjct: 1522 SQTARIMELEDHITQKTIEIESL---NEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN 1578

Query: 138  RMKELEAELAMAKQSLATLTKDV 160
            R+KE E ++   +  + ++  ++
Sbjct: 1579 RVKEAEEKILTLENQVYSMKAEL 1601



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 28/134 (20%), Positives = 65/134 (48%), Gaps = 7/134 (5%)

Query: 25  ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
           +L + L ++++ L   +  ++ ++AD KR +GE    + Q        +S +    +  +
Sbjct: 760 QLELLLKERDKHLKEHQAHVENLEADIKRSEGE----LQQASAKLDVFQSYQSATHEQTK 815

Query: 85  NYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 144
            YE+   + +  +  L  E+ LL ++  E+  Q K+      A + Q+    + M++LE 
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV---QDLMQQLEK 872

Query: 145 ELAMAKQSLATLTK 158
           + +  +Q + +LT+
Sbjct: 873 QNSEMEQKVKSLTQ 886



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 20/151 (13%)

Query: 7    KDLEESQGGKSSEVLSATELRVQLAQKEQELARA-KEAL-QAMKADRKRLKGEKTDLVSQ 64
            +DLE        +++   E   QLAQKEQEL    KE + +A + + + L+  +     +
Sbjct: 1984 EDLELKHNSTLKQLMR--EFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQ----EE 2037

Query: 65   MQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKE-----KDLLEREKWELRRQAK 119
              QL   +  +++ L+   + YE+     E+ + A  ++     ++L ++ + +L ++  
Sbjct: 2038 TNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2097

Query: 120  EATDHATALRSQLDL-------KDNRMKELE 143
               D+ T +  Q  L        D+++KE E
Sbjct: 2098 PGNDNVTIMELQTQLAQKTTLISDSKLKEQE 2128



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 41/184 (22%), Positives = 76/184 (41%), Gaps = 31/184 (16%)

Query: 2   KEMLAKDLEESQGGKSSEVLSATE---LRVQLAQKEQELARAKEALQAMKADRKRLKGEK 58
           + +L +  E  Q  K    L  +E   L+ QL ++ QEL + K+   A K        + 
Sbjct: 292 ENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 351

Query: 59  TDLVSQMQQ------------LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDL 106
            +L+ Q++Q            ++ TLE +EE++       +Q   + E+    L ++K+ 
Sbjct: 352 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEE----LREQKEK 407

Query: 107 LEREKWELRRQAKEATDHATALRSQLDLK-DNRMK-----------ELEAELAMAKQSLA 154
            ER  +E   +A          R +L  + D ++K            L+ EL+  KQ + 
Sbjct: 408 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 467

Query: 155 TLTK 158
            + K
Sbjct: 468 DVMK 471



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 31/194 (15%)

Query: 3   EMLAKDLEESQGGKSSEVLSATELRVQLAQKE----QELARAKEALQAMKADRKRLKGEK 58
           EM  +++ + +           ELR Q  + E    +EL +A    Q  +  R++LK E 
Sbjct: 378 EMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAE- 436

Query: 59  TDLVSQMQQLYATLESREEQLRDFIRN---------YEQHRKESEDAVKALAK--EKDLL 107
                 M +   T+E   E+ R  ++           +  +K SE+ +  L K  EK+L 
Sbjct: 437 ------MDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELA 490

Query: 108 ERE-----KWELRRQAKEATDHATALRSQLD-LKDNRMKELEAELAMAK---QSLATLTK 158
            +E     K + R +  +        +SQ + LK ++ KE +  LA+ +   Q  A LT+
Sbjct: 491 RKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTE 550

Query: 159 DVPKRHSLAMPGET 172
              K   L    ET
Sbjct: 551 SENKLRDLQQEAET 564



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 41/171 (23%), Positives = 77/171 (45%), Gaps = 14/171 (8%)

Query: 2   KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
           KE L KD E        E+   T  ++ + Q E E + + E  + +KA R +L+ E + L
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELE-SLSSELSEVLKA-RHKLEEELSVL 710

Query: 62  VSQMQQLYATLESR--------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE 113
             Q  ++   LE++        ++Q+   I+ +E   + +E   KAL  + + LE    E
Sbjct: 711 KDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTE---KALKDQINQLELLLKE 767

Query: 114 LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRH 164
             +  KE   H   L + +   +  +++  A+L +  QS  + T +  K +
Sbjct: 768 RDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF-QSYQSATHEQTKAY 817



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 27/132 (20%), Positives = 59/132 (44%), Gaps = 16/132 (12%)

Query: 32   QKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRK 91
            +K+  +  A+E +  ++     +K E      +++ +  +++S+EE+L+       + R 
Sbjct: 1575 EKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL-----EDRL 1629

Query: 92   ESEDAV-----------KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK 140
            ESE A            K  A +K LL + + +  +  K    H + L ++L  ++  + 
Sbjct: 1630 ESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVH 1689

Query: 141  ELEAELAMAKQS 152
             LE +L   + S
Sbjct: 1690 ILEEKLKSVESS 1701


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 33/135 (24%), Positives = 68/135 (50%), Gaps = 5/135 (3%)

Query: 27   RVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY---ATLESREEQLRDFI 83
            R+Q A++  E A +K A  +++  ++RL+GE  DL+  +++ +   ATL+ ++      +
Sbjct: 1400 RLQEAEENTETANSKCA--SLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVL 1457

Query: 84   RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
              ++Q   ES+  ++A  KE   L  E +++R   +E  D    LR +       + +L 
Sbjct: 1458 AEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLT 1517

Query: 144  AELAMAKQSLATLTK 158
             ++A   ++L    K
Sbjct: 1518 EQIAETGKNLQEAEK 1532



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 17/161 (10%)

Query: 16  KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
           K   +L + E   ++A  +++  R KE L   +A RK L+        EK DL  Q+Q  
Sbjct: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898

Query: 69  YATLESREEQLRDFIRN----------YEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
              L   EE+    I++            +  +E E+    L  +K  LE +   L+R  
Sbjct: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958

Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
            +     T +  +    +N++K L  E+   +++++ LTK+
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKE 999



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 49/180 (27%), Positives = 81/180 (45%), Gaps = 22/180 (12%)

Query: 1    MKEMLAKDLEESQGGKSSEVLSATELRVQLAQ-------KEQELARAKEALQAMKADRKR 53
            +KE LA  + E + G   E L   E++V L Q        EQEL  A + +Q + +    
Sbjct: 1671 LKEQLA--IVERRNGLLLEELE--EMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTS 1726

Query: 54   LKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDL---LERE 110
            L   K  L + + Q  A +E+  ++ R+     ++   ++    + L KE+D    LER 
Sbjct: 1727 LINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1786

Query: 111  KWELRRQAKEAT---DHATAL-----RSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK 162
            K  L +  K+     D A  L     + Q+   +NR++ELE EL + ++  A   K   K
Sbjct: 1787 KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHK 1846



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 40/205 (19%), Positives = 84/205 (40%), Gaps = 49/205 (23%)

Query: 8    DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
            +L + Q     E + + + + ++ + +  +   +E ++A    R +++ +++DL  ++++
Sbjct: 1090 ELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEE 1149

Query: 68   LYATLES--------------REEQLRDFIRNYE----QH-------RKESEDAVKALAK 102
            +   LE               RE + +   R+ E    QH       RK+  D+V  L +
Sbjct: 1150 ISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGE 1209

Query: 103  E-------KDLLEREKWELRRQAKEATDHATALR-----------------SQLDLKDNR 138
            +       K  LE+EK EL+ +  +   +  AL                  S++  KD +
Sbjct: 1210 QIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQ 1269

Query: 139  MKELEAELAMAKQSLATLTKDVPKR 163
              +L  +L M K  L T   ++  R
Sbjct: 1270 QTQLIHDLNMQKARLQTQNGELSHR 1294



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 9/142 (6%)

Query: 18   SEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREE 77
            SE+ +  E + QL     +L   K  LQ    +      EK  L+SQ+ +    L  + E
Sbjct: 1261 SEIKAKDEQQTQLIH---DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLE 1317

Query: 78   QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
            +L+  +    + +     A+++   + DLL RE++E  ++AK     A +  +    +  
Sbjct: 1318 ELKRQMEEETKAKNAMAHALQSSRHDCDLL-REQYEEEQEAKAELQRALSKANSEVAQWR 1376

Query: 138  RMKELEA-----ELAMAKQSLA 154
               E +A     EL  AK+ LA
Sbjct: 1377 TKYETDAIQRTEELEEAKKKLA 1398



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 25/134 (18%), Positives = 56/134 (41%), Gaps = 3/134 (2%)

Query: 25   ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
            EL  ++ +KE  +++  ++ QA+    + LK +  +       +   L+S          
Sbjct: 1290 ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349

Query: 85   NYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 144
             YE+ ++   +  +AL+K    + + + +    A + T+     + +L     R++E E 
Sbjct: 1350 QYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL---AQRLQEAEE 1406

Query: 145  ELAMAKQSLATLTK 158
                A    A+L K
Sbjct: 1407 NTETANSKCASLEK 1420



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 29/126 (23%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 25   ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
            E+ +QL    +++A  ++ L+ ++       G+  D    +     + E  +EQL    R
Sbjct: 1628 EMEIQLGHSNRQMAETQKHLRTVQ-------GQLKDSQLHLDDALRSNEDLKEQLAIVER 1680

Query: 85   NYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 144
                  +E E+   AL +     ER +    ++  +A+D    L SQ     N  K+LEA
Sbjct: 1681 RNGLLLEELEEMKVALEQT----ERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEA 1736

Query: 145  ELAMAK 150
            ++A  +
Sbjct: 1737 DIAQCQ 1742


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 17/161 (10%)

Query: 16   KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
            K   +L + +   +LA    EL   + AL A +A R+ L+        EK DL  Q+Q  
Sbjct: 884  KMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943

Query: 69   YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
               L   EE+    I++  Q          R E E+ V A LA  +  LE E  EL++  
Sbjct: 944  QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003

Query: 119  KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
             +          +    +N++K L  E+A   +S+A LTK+
Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 1044



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 45/170 (26%), Positives = 75/170 (44%), Gaps = 18/170 (10%)

Query: 4    MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVS 63
            +LA +LEE +       L   E   +LA  EQEL  A E L  + +    L  +K  L +
Sbjct: 1729 LLAAELEELRAA-----LEQGERSRRLA--EQELLEATERLNLLHSQNTGLLNQKKKLEA 1781

Query: 64   QMQQLYATLESREEQLRDFIRNYE----------QHRKESEDAVKALAKEKDLLEREKWE 113
             + QL   +E   ++ R+     +          +  K+ +D    L + K  LE+   E
Sbjct: 1782 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1841

Query: 114  LRRQAKEATDHAT-ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK 162
            L+ + +EA   A    + Q+   + +++ELEAEL   ++  A   K V K
Sbjct: 1842 LQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRK 1891



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 7/132 (5%)

Query: 27   RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
            +VQL  K +EL+   E  + + AD    R++L+ E T+L   +  L  TL   E  ++  
Sbjct: 961  KVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQAT 1020

Query: 80   RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
             + ++N  +     +++V  L KEK  L+    +     +   D  +AL       + ++
Sbjct: 1021 ENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQV 1080

Query: 140  KELEAELAMAKQ 151
            ++LE  L   K+
Sbjct: 1081 EDLECSLEQEKK 1092



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 7/146 (4%)

Query: 2    KEMLAKDLEE--SQGGKSSEVLSATELRVQLAQKEQELARAKEALQA-MKADRKRLKGEK 58
            K + A+ LEE   Q  + S+  SA    VQ  + + +L R +   +A  +A+ +RL  + 
Sbjct: 1354 KALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKA 1413

Query: 59   TDLVSQMQQLY-ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQ 117
               V+Q +  Y A    R E+L +  +      +E+E+ V+A   +   LE+ K  L+ +
Sbjct: 1414 NAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTE 1473

Query: 118  AKEAT---DHATALRSQLDLKDNRMK 140
            +++ T   + AT+  + LD K   ++
Sbjct: 1474 SEDVTLELERATSAAAALDKKQRHLE 1499



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 37/159 (23%), Positives = 72/159 (45%), Gaps = 11/159 (6%)

Query: 2    KEMLAKDLEESQGGKSS-----EVLSATELRVQLAQKEQ--ELARAKEALQAMKADRKRL 54
            K+ LA  L+E++ G  +       L   +LR+Q   ++   EL RA  A  A+   ++ L
Sbjct: 1439 KKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHL 1498

Query: 55   KGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL 114
            +    +   Q +++   LE+ + + R       + R   E+A++AL    + L+RE   L
Sbjct: 1499 ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL----ETLKRENKNL 1554

Query: 115  RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
            + +  + TD  +     +   +   K LE E +  + +L
Sbjct: 1555 QEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAAL 1593



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 62/296 (20%), Positives = 113/296 (38%), Gaps = 30/296 (10%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ-------AMKADRKRL 54
            K  L  DL+ +Q   +       +L  +L +K+ EL++    ++        M+   K L
Sbjct: 1101 KRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKEL 1160

Query: 55   KGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL 114
            +    +L  +++   A     E+Q  +  R  E+  +  E+A  A A +++   + + EL
Sbjct: 1161 QARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAEL 1220

Query: 115  RRQAKEATDHATALRSQLDLKDNRMKELE--AELAMAKQSLATLTKDVPKRHSLAMPGET 172
             R  +E  +   ALR +  +   R K+ E  AEL     SL  + + + K  S       
Sbjct: 1221 GRLRRELEE--AALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVD 1278

Query: 173  VLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAA 232
             L  N E + +A        R  +  L             ++V     +    ++DAS  
Sbjct: 1279 DLAANVETLTRAKASAEKLCRTYEDQL---------SEAKIKVEELQRQ----LADASTQ 1325

Query: 233  EGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEK 288
             G   +   +++        L +  S G           QSLE+L  Q  ++ K K
Sbjct: 1326 RGRLQTESGELSRLLEEKECLISQLSRGKAL------AAQSLEELRRQLEEESKAK 1375



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 13/141 (9%)

Query: 24   TELRVQLAQKEQELARA---KEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
            +E ++++ + +++LA A   +  LQ    +  RL  EK  L+SQ+ +  A      E+LR
Sbjct: 1306 SEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELR 1365

Query: 81   DFIRNYEQHRKESEDAVKALAKEKDLLERE-------KWELRRQAKEATDHATALRSQLD 133
              +    + +     AV+AL  + DLL  +       + EL+R   +A       RS+ +
Sbjct: 1366 RQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYE 1425

Query: 134  LKDNRMKELEAELAMAKQSLA 154
                +  E   EL  AK+ LA
Sbjct: 1426 ADAIQRTE---ELEEAKKKLA 1443



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 53/188 (28%), Positives = 86/188 (45%), Gaps = 48/188 (25%)

Query: 6    AKDLEESQGGKSSEVLSATELRV--QLAQKEQELA-------RAKEALQA-MKAD----- 50
            A +LEE++  +    LS  +  V  +LA+K++E A       RA E+LQA + A+     
Sbjct: 1599 ALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARN 1658

Query: 51   -----RKRLKGEKTDLVSQMQQLYATLESREEQLRDFI-----------RNYEQH-RKES 93
                 +K+++G+  DL  ++Q  +AT ++ E Q    +           R+ EQ    E 
Sbjct: 1659 EALRLKKKMEGDLNDL--ELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAEL 1716

Query: 94   EDAVKALAKEKDLLEREKWELR--------------RQAKEATDHATALRSQLDLKDNRM 139
             +  +AL +   LL  E  ELR              ++  EAT+    L SQ     N+ 
Sbjct: 1717 HEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQK 1776

Query: 140  KELEAELA 147
            K+LEA+LA
Sbjct: 1777 KKLEADLA 1784



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 40/163 (24%), Positives = 70/163 (42%), Gaps = 38/163 (23%)

Query: 2    KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
            +E + ++LE +Q  + S  L     R++   +E     A EAL+ +K + K L+ E +DL
Sbjct: 1509 EEEMQRELEAAQ--RESRGLGTELFRLRHGHEE-----ALEALETLKRENKNLQEEISDL 1561

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
              Q+                           S  +++ L K K  LE EK E++   +EA
Sbjct: 1562 TDQVSL-------------------------SGKSIQELEKTKKALEGEKSEIQAALEEA 1596

Query: 122  -----TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
                  +    LR QL+L   +  E++ +LA   +  A L ++
Sbjct: 1597 EGALELEETKTLRIQLELSQVK-AEVDRKLAEKDEECANLRRN 1638



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 7/136 (5%)

Query: 1    MKEMLAKDLEESQ-----GGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLK 55
            ++E+ A+ LEE++     GGK        ++R   A+ + E  +  EAL+ ++   +R+K
Sbjct: 1839 VRELQAR-LEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVK 1897

Query: 56   GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
             E      + ++  A ++   ++L+  +++Y++  +E+E        +    + E  +  
Sbjct: 1898 -ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAE 1956

Query: 116  RQAKEATDHATALRSQ 131
             +A  A   A  LR++
Sbjct: 1957 ERADMAETQANKLRAR 1972



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 25/128 (19%), Positives = 60/128 (46%), Gaps = 4/128 (3%)

Query: 26   LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
            L+ +++    +++ + +++Q ++  +K L+GEK+++ + +++    LE  E +       
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613

Query: 86   YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ-LDLK---DNRMKE 141
              Q + E +  +    +E   L R         + + D  T  R++ L LK   +  + +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1673

Query: 142  LEAELAMA 149
            LE +L  A
Sbjct: 1674 LELQLGHA 1681



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 11/168 (6%)

Query: 3    EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADR-KRLKGEKTDL 61
            + L  D +  +     E  +  EL+  L++   E+A+ +   +A    R + L+  K  L
Sbjct: 1383 QALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKL 1442

Query: 62   VSQMQQLYATLESREEQLRDFIRNYEQHRKESED----------AVKALAKEKDLLEREK 111
              ++Q+    +E+   +     +   + + ESED          A  AL K++  LER  
Sbjct: 1443 ALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERAL 1502

Query: 112  WELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
             E RRQ +E      A + +       +  L      A ++L TL ++
Sbjct: 1503 EERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRE 1550


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,368,889
Number of Sequences: 37866
Number of extensions: 569306
Number of successful extensions: 6645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 349
Number of HSP's successfully gapped in prelim test: 661
Number of HSP's that attempted gapping in prelim test: 3481
Number of HSP's gapped (non-prelim): 3002
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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